• Outcomes After Transcervical Thymectomy for Ocular Myasthenia Gravis: A Retrospective Cohort Study With Inverse Probability Weighting

  Background: The benefit of thymectomy in reducing requirement for corticosteroids, symptom severity, need for immunosuppression, and hospitalization rates in patients with seropositive generalized myasthenia has recently been established. It is unclear whether this benefit applies to patients with myasthenia and purely ocular manifestations (ocular myasthenia gravis [OMG]). Methods: We conducted a retrospective single-center cohort study

  North American Neuro-Ophthalmology Society

  Wed Aug 21, 2019 17:00
• Hereditary Angiopathy With Nephropathy, Aneurysm, and Muscle Cramps (HANAC) Syndrome Presenting to Neuro-Ophthalmology With Metamorphopsia

  No abstract available

  North American Neuro-Ophthalmology Society

  Wed Aug 21, 2019 17:00
• Neurocognitive Assessment and Retinal Thickness Alterations in Alzheimer Disease: Is There a Correlation?

  Background: The relation of retinal thickness to neuropsychological indexes of cognitive impairment in patients with Alzheimer disease (AD) remains an area of investigation. The scope of this investigation was to compare volume and thickness changes of neuronal retinal layers in subjects with AD with those of age-matched healthy controls and to estimate the relation between cognitive functioning evaluated by neuropsychological assessment and t

  North American Neuro-Ophthalmology Society

  Wed Aug 21, 2019 17:00
• A Reliability and Comparative Analysis of the New Randomized King-Devick Test

  Objective: The King-Devick (K-D) test is a rapid visual screening tool that can assess underlying brain trauma such as concussion via impairments in saccadic rhythm. A new tablet version of the K-D test using randomized numbers is now available, but reliability for this new version and comparison to the traditional K-D test has not yet been reported. Known for learning effects in the test, the aim of this study was to determine test–retest rel

  North American Neuro-Ophthalmology Society

  Wed Aug 21, 2019 17:00
• Asymmetric Inferior Predilection of Lisch Nodules With Unilateral Ptosis

  Abstract: Lisch nodules are melanocytic hamartomas that have been hypothesized to grow larger in the presence of sunlight. A 17-year-old boy with neurofibromatosis Type 1 and congenital ptosis in one eye presented and was found to have a distinct asymmetry of Lisch nodules between eyes with less under the ptotic lid. This case supports the theory that Lisch nodules form at least partially due to a direct trophic effect of sunlight. Address c

  North American Neuro-Ophthalmology Society

  Wed Aug 21, 2019 17:00
• Recurrent Optic Perineuritis as the First Manifestation of Relapsing Polychondritis

  No abstract available

  North American Neuro-Ophthalmology Society

  Wed Aug 21, 2019 17:00
• Orbicularis Oculi Morphological Alterations in Affected and Nonaffected Sides in Hemifacial Spasm

  Background: Although the nonaffected side appears to be clinically normal in hemifacial spasm (HFS), it is not known whether this side can be considered normal regarding histopathological findings. The purpose of this study was to objectively evaluate and compare orbicularis oculi samples of patients with HFS (not previously treated with botulinum toxin) and control patients undergoing cosmetic upper eyelid blepharoplasty. Methods: Orbicu

  North American Neuro-Ophthalmology Society

  Wed Aug 21, 2019 17:00
• Intravitreal Triamcinolone Acetonide Injection in a Rodent Model of Anterior Ischemic Optic Neuropathy: Response

  No abstract available

  North American Neuro-Ophthalmology Society

  Wed Aug 21, 2019 17:00
• Third Nerve Palsy Due to a Malignant Oculomotor Nerve Sheath Tumor

  No abstract available

  North American Neuro-Ophthalmology Society

  Wed Aug 21, 2019 17:00
• The current status of non-radiologist-performed abdominal ultrasonography in paediatrics – a scoping literature review protocol

  Abstract In recent years as a result of decreasing prices and the increasing availability of portable systems, ultrasonography (US), which historically has primarily been the domain of radiologists, has become more widely available to non-radiologists as well. This has increased the use of point-of-care paediatric US performed by non-radiologists. With this scoping review, focused on abdominal imaging, we aim to gain an overv

  Pediatric Radiology

  Mon Aug 26, 2019 20:25
• Pediatric Radiology continuing medical education activity

  Pediatric Radiology

  Mon Aug 26, 2019 20:25
• Hermes

  Pediatric Radiology

  Mon Aug 26, 2019 20:25
• Three-dimensional ocular endoscope system for vitrectomy

  Clinical Ophthalmology

  Mon Aug 26, 2019 20:23
• Extended depth of focus lens implantation after radial keratotomy [Response to Letter]

  Clinical Ophthalmology

  Mon Aug 26, 2019 19:18
• Extended depth of focus lens implantation after radial keratotomy [Letter]

  Clinical Ophthalmology

  Mon Aug 26, 2019 19:13
• Efficacy and safety of tafluprost 0.0015% – retrospective analysis of real-world data from the Philippines

  Clinical Ophthalmology

  Mon Aug 26, 2019 19:06
• Dual-Plane Undermining and Galeal Stitch for Dermal Tension Relief in High-Tension Defects, Hemostats for High-Tension Knot Placement, and Debeveling for Exact Dermal Approximation: A Video Walk-Through

  No abstract available

  Dermatologic Surgery - Current Issue

  Mon Aug 26, 2019 20:20
• Repair of a Large Sternal Notch Defect

  No abstract available

  Dermatologic Surgery - Current Issue

  Mon Aug 26, 2019 20:20
• Stratification of Poor Outcomes for Cutaneous Squamous Cell Carcinoma in Immunosuppressed Patients Using the American Joint Committee on Cancer Eighth Edition and Brigham and Women's Hospital Staging Systems

  BACKGROUND Staging systems for cutaneous squamous cell carcinoma (CSCC) include Brigham and Women's Hospital (BWH) and American Joint Committee on Cancer staging system, eighth edition (AJCC-8). OBJECTIVE To evaluate and compare AJCC-8 and BWH staging systems for CSCC in immunosuppressed patients. MATERIALS AND METHODS A retrospective cohort study of immunosuppressed patients diagnosed with primary CSCC from 2012 to 2016. The main e

  Dermatologic Surgery - Current Issue

  Mon Aug 26, 2019 20:20
• Successful Surgical Treatment of Bilateral Congenital Malalignment of the Great Toenail and Hypertrophic Lateral Nail Folds

  No abstract available

  Dermatologic Surgery - Current Issue

  Mon Aug 26, 2019 20:20
• Comparison of Mohs Surgery and Surgical Excision in the Treatment of Localized Sebaceous Carcinoma

  BACKGROUND It remains controversial if Mohs surgery is superior to surgical excision in treating localized sebaceous carcinoma. OBJECTIVE To compare Mohs surgery and surgical excision for treating patients with localized sebaceous carcinoma. MATERIALS AND METHODS The US National Cancer Database was used to identify patients with histologically confirmed Stage 0 to 2 sebaceous carcinoma from 2004 to 2014. Clinicopathologic and socioe

  Dermatologic Surgery - Current Issue

  Mon Aug 26, 2019 20:20
• In the Crosshairs: Loss of Vellus Hair Follicles in Basal Cell Carcinoma. A Clue to Clinical Margin

  No abstract available

  Dermatologic Surgery - Current Issue

  Mon Aug 26, 2019 20:20
• Mechanical Strain of the Nasal Bilobed Transposition Flap—Graduated Changes in Skin Thickness Superiorly Displace the Location of the Pivot Point

  BACKGROUND The bilobed transposition flap recruits the relatively thinner and laxer skin of the nasal dorsum and sidewall to reconstruct defects of the more sebaceous nasal tip and alae. There have been no studies performed to quantify how the material properties of skin alter the bilobed flap's performance during nasal reconstruction. OBJECTIVE To determine the effects of skin thickness and stiffness on bilobed flap mechanics to help gu

  Dermatologic Surgery - Current Issue

  Mon Aug 26, 2019 20:20
• Intralesional Steroids and Compression Devices for Keloids

  No abstract available

  Dermatologic Surgery - Current Issue

  Mon Aug 26, 2019 20:20
• Comparison of Surgical Outcomes of Rectangular Lid Excision Versus Elliptical Excision for the Treatment of Epidermal Cysts

  BACKGROUND Elliptical excision (EE) has been the standard surgical technique for the removal of epidermal cysts. However, it produces to create a long, linear wound causing cosmetic concerns. OBJECTIVE The purpose of the study was to evaluate the cosmetic outcomes and postoperative complications of rectangular lid excision (LE) compared with EE in epidermal cyst removals. METHODS Medical records of patients who received surgical exc

  Dermatologic Surgery - Current Issue

  Mon Aug 26, 2019 20:20
• Outcomes of Adjuvant Radiotherapy Following Negative Surgical Margins for Cutaneous Squamous Cell Carcinoma

  BACKGROUND The role of adjuvant radiotherapy (ART) for cutaneous squamous cell carcinoma (cSCC) following negative surgical margins is unclear. OBJECTIVE To retrospectively examine the clinical outcomes in a cohort of patients with cSCC who completed ART after Mohs micrographic surgery or wide local excision with negative margins. METHODS AND MATERIALS After the institutional review board approval, a retrospective review was conduct

  Dermatologic Surgery - Current Issue

  Mon Aug 26, 2019 20:20
• A Novel Combined Light-Based Treatment of Acne Vulgaris With 1,450-nm Diode Laser and 450-nm Blue Light

  BACKGROUND Nonablative 1,450-nm diode laser (DL) and visible blue light (BL) have been effectively used for acne with superior safety profiles. OBJECTIVE To evaluate synergistic effects of sequential DL and BL application for acne. METHODS A 20-week, randomized split-face study was conducted to compare clinical courses between 2 facial sides either receiving sequential application of DL and BL or BL alone in 24 patients with mild to

  Dermatologic Surgery - Current Issue

  Mon Aug 26, 2019 20:20
• Recognition of Alkaptonuria During Mohs Micrographic Surgery

  No abstract available

  Dermatologic Surgery - Current Issue

  Mon Aug 26, 2019 20:20
• Assessment of Skin Physiology Change and Safety After Intradermal Injections With Botulinum Toxin: A Randomized, Double-Blind, Placebo-Controlled, Split-Face Pilot Study in Rosacea Patients With Facial Erythema

  BACKGROUND Botulinum toxin (BTX) has been used cosmetically with good clinical efficacy and tolerable safety. OBJECTIVE This randomized, double-blind, split-face clinical study aimed to investigate the efficacy and safety of intradermal BTX in patients with rosacea. MATERIALS AND METHODS Twenty-four participants were enrolled and randomly given intradermal injections of BTX and normal saline in both cheeks. Clinician Erythema Assess

  Dermatologic Surgery - Current Issue

  Mon Aug 26, 2019 20:20
• A Wrong-Site Surgery Protocol for Dermatological Surgery

  No abstract available

  Dermatologic Surgery - Current Issue

  Mon Aug 26, 2019 20:20
• Crescentic Modification to Island Pedicle Rotation Flaps for Defects of the Distal Nose

  BACKGROUND Island pedicle flaps based on a lateral sling of the nasalis have difficulty reaching distal nasal defects due to tethering of the muscle to its insertion point. The authors hypothesized that reach could be improved by modifying a crescentic flap to rotate around a pivot point equidistant to the flap and the defect. OBJECTIVE To describe the design, execution, and results with a modified crescentic island pedicle rotation flap

  Dermatologic Surgery - Current Issue

  Mon Aug 26, 2019 20:20
• The Use of Human Amnion/Chorion Membrane and Umbilical Cord Grafts for Treatment of a Scalp Wound With Exposed Bone

  No abstract available

  Dermatologic Surgery - Current Issue

  Mon Aug 26, 2019 20:20
• Cellulite: Patient Selection and Combination Treatments for Optimal Results—A Review and Our Experience

  BACKGROUND More than 90% of women have reported concerns of cellulite on their skin. Both commercially advertised creams and topical pharmacological agents have shown limited improvement. Thus far, there has been a paucity of thorough review articles on how to address and treat this condition. OBJECTIVE To investigate how the etiology and pathogenesis of cellulite can help guide treatment combinations and provide a more algorithmic appro

  Dermatologic Surgery - Current Issue

  Mon Aug 26, 2019 20:20
• Methods of Standardizing Photography for Cellulite in the Buttocks and Thighs

  No abstract available

  Dermatologic Surgery - Current Issue

  Mon Aug 26, 2019 20:20
• Cryolipolysis for Noninvasive Contouring of the Periumbilical Abdomen With a Nonvacuum Conformable-Surface Applicator

  BACKGROUND Although most cryolipolysis treatments are performed with vacuum applicators, some patients may have areas of fibrous, nonpinchable fat or find vacuum suction to be uncomfortable. OBJECTIVE This study evaluates a nonvacuum conformable-surface applicator for cryolipolysis of the periumbilical abdomen. METHODS/MATERIALS Twenty subjects with periumbilical subcutaneous fat were treated with a nonvacuum cryolipolysis applicato

  Dermatologic Surgery - Current Issue

  Mon Aug 26, 2019 20:20
• Stability of Hyaluronic Acid Fillers After Insulated Microneedle Radiofrequency Treatment

  No abstract available

  Dermatologic Surgery - Current Issue

  Mon Aug 26, 2019 20:20
• Quantification of 18F-DCFPyL Uptake: TBR versus Patlaks Analysis.

  The Journal of Nuclear Medicine (JNM)

  Mon Aug 26, 2019 11:19
• Is the "VISION" of Radioligand Therapy for Prostate Cancer becoming reality?An Overview of the Phase III trial and the Importance for the Future of Theranostics

  The Journal of Nuclear Medicine (JNM)

  Mon Aug 26, 2019 11:19
• 131I-IITM and 211At-AITM: Two Novel Small-molecule Radiopharmaceuticals Targeting Oncoprotein Metabotropic Glutamate Receptor 1

  Targeted radionuclide therapy (TRT) targeting oncoproteins facilitates the delivery of therapeutic radionuclides to tumor tissues with high precision. Herein, we developed two new radiopharmaceuticals, 4-131I-iodo- and 4-211At-astato-N-[4-(6-(isopropylamino)pyridine-4-yl)-1,3-thiazol-2-yl]-N-methylbenzamide (131I-IITM and 211At-AITM), targeting the ectopic metabotropic glutamate receptor 1 (mGluR1) in melanomas for TRT studies. Methods: 131I-II

  The Journal of Nuclear Medicine (JNM)

  Mon Aug 26, 2019 11:19
• FDG-PET/CT AS A NON-INVASIVE BIOMARKER FOR ASSESSING ADEQUACY OF TREATMENT AND PREDICTING RELAPSE IN PATIENTS TREATED FOR PULMONARY TUBERCULOSIS

  Background: Microbial culture is the gold standard for determining the effectiveness of tuberculosis treatment. End-of-treatment (EOT) FDG-PET/CT findings are variable among patients with negative microbial culture after completing standard regimen of anti-tuberculous treatment (ATT) with some patients having a complete metabolic response to treatment while others have residual metabolic activity (RMA). We herein determine the impact of findings

  The Journal of Nuclear Medicine (JNM)

  Mon Aug 26, 2019 11:19
• Nationwide survey of implementation of 2011 Nuclear Regulatory Commission policy on release of patients after 131I therapy

  The objective of this nationwide survey was to evaluate whether there has been a change in the practice regarding hospital release of differentiated thyroid cancer patients treated with 131I since the publication of Nuclear Regulatory Commission Regulatory Issue Summary 2011-01 addressing patient release. Methods: A survey was emailed to ~25,000 members of ThyCa: Thyroid Cancer Survivors’ Association, Inc. and was available online from March-

  The Journal of Nuclear Medicine (JNM)

  Mon Aug 26, 2019 11:19
• Comparative Prognostic and Diagnostic Value of Myocardial Blood Flow and Myocardial Flow Reserve After Cardiac Transplant

  Rationale: Cardiac allograft vasculopathy (CAV) is a major cause of graft failure after cardiac transplantation. CAV is characterized by diffuse involvement of epicardial coronary arteries and the microvasculature. Positron emission tomography (PET) allows quantification of absolute myocardial blood flow (MBF) and myocardial flow reserve (MFR), which may be accurate markers of CAV severity. We compared the diagnostic and prognostic utility of str

  The Journal of Nuclear Medicine (JNM)

  Mon Aug 26, 2019 11:19
• Prospective Comparison of PET Imaging with PSMA-targeted 18F-DCFPyL versus Na18F for Bone Lesion Detection in Patients with Metastatic Prostate Cancer

  Purpose: Bone metastases in prostate cancer (PCa) have important prognostic significance and imaging modalities used for PCa staging should have high sensitivity for detecting such lesions. Prostate-specific membrane antigen (PSMA)-targeted positron emission tomography (PET) radiotracers are promising new agents for imaging PCa. We undertook a head-to-head comparison of PSMA-targeted 18F-DCFPyL PET to Na18F PET to determine which modality was mor

  The Journal of Nuclear Medicine (JNM)

  Mon Aug 26, 2019 11:19
• Reply to: Quantification of 18F-DCFPyL Uptake: TBR versus Patlaks Analysis

  The Journal of Nuclear Medicine (JNM)

  Mon Aug 26, 2019 11:19
• Exon 3 of the NUMB Gene Emerged in the Chordate Lineage Coopting the NUMB Protein to the Regulation of MDM2

  MDM2 regulates a variety of cellular processes through its dual protein:protein interaction and ubiquitin ligase activities. One major function of MDM2 is to bind and ubiquitinate P53, thereby regulating its proteasomal degradation. This function is in turn controlled by the cell fate determinant NUMB, which binds to and inhibits MDM2 via a short stretch of 11 amino acids, contained in its phosphotyrosine-binding (PTB) domain, encoded by exon 3 o

  G3: .Genes, Genomes, Genetics Mission - Online First Articles

  Mon Aug 26, 2019 13:44
• Stevens–Johnson syndrome and acute vanishing bile duct syndrome after the use of amoxicillin...

  Stevens–Johnson syndrome and acute vanishing bile duct syndrome after the use of amoxicillin and naproxen in a childJournal of International Medical Research, Ahead of Print.SAGE Publications Ltd: Journal of International Medical Research: Table of ContentsMon Aug 26, 2019 03:28Recurrence of a symptomatic spinal intradural arachnoid cyst 29 years after fenestrationJournal of International Medical Research, Ahead of Print.SAGE Publications

  Αλέξανδρος Γ. Σφακιανάκης

  Mon Aug 26, 2019 23:43
• Destabilization of the Tumor-Inducing Plasmid from an Octopine-Type Agrobacterium tumefaciens Lineage Drives a Large Deletion in the Co-resident at Megaplasmid

  Bacteria with multi-replicon genome organizations, including members of the family Rhizobiaceae, often carry a variety of niche-associated functions on large plasmids. While evidence exists for cross-replicon interactions and co-evolution between replicons in many of these systems, remarkable strain-to-strain variation is observed within secondary replicons, suggesting environment-dependent fitness benefits of the accessory genome. Here, we show

  G3: .Genes, Genomes, Genetics Mission - Online First Articles

  Mon Aug 26, 2019 13:44
• Study of Vitamin D Level and Vitamin D Receptor Polymorphism in Hypothyroid Egyptian Patients

  Purpose. The current study aimed at assessing vitamin D level and vitamin D receptor polymorphism in hypothyroid Egyptian patients and its effect on hypothyroidism and thyroid morphology, also to find a causal relation between vitamin D and hypothyroidism. Methods. This case-control study was conducted on 35 hypothyroid patients and 35 matched unrelated healthy controls. Total serum 25-hydroxyvitamin D3 and thyroid antibodies were measured using

  Journal of Thyroid Research

  Mon Aug 26, 2019 02:05
• Emphysematous Aortitis due to Clostridium septicum in an 89-Year-Old Female with Ileus

  Emphysematous aortitis is a rare but lethal form of infectious vasculitis. This condition was found incidentally on computed tomography of the chest during the evaluation of a patient presenting with pneumonia coincident with adynamic ileus. The patient did not have a history of malignancy. While colon cancer could not be ruled out, it is possible that ileus may have contributed to or resulted in bacterial translocation in this case. Appropriate

  Case Reports in Infectious Diseases

  Mon Aug 26, 2019 17:05
• Experimental and Finite Element Method Studies for Femtomolar Cobalt Ions Detection by a DHI Modified Nanochannel

  Analyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN01344J, PaperXuye Liu, Qiang Zeng, Cheng Liu, Jie Yang, Lishi WangIn this work, a sensing nanochannel basing on N-[3-(triethoxysilyl)propyl]-4,5-dihydroimidazole (DHI) modified nanopipette was prepared and characterized for the ultrasensitive detection of cobalt ions (Co2+) in aqueous solutions. By both experimental...The content of this RSS Feed (c) The Royal Society of Chemistry

  Royal Society of Chemistry (Great Britain) Society for Analytical Chemistry Society of Public Analysts (Great Britain)

  Mon Aug 26, 2019 16:00
• Short and long-term effects of CDK4/6 inhibition on early stage breast cancer

  CDK4/6 inhibitors are used in the treatment of advanced estrogen receptor (ER)(+) breast cancer (BC). Their efficacy in ER(-) and early stage BC is currently under investigation. Here, we show that palbociclib, a CDK4/6 inhibitor, can inhibit both progression of ductal carcinoma in situ (DCIS) and growth of invasive disease in both an ER(-) basal BC model (MCFDCIS) and an ER(+) luminal model (MCF7 intraductal injection). In MCFDCIS cells palbocic

  Molecular Cancer Therapeutics Online First Articles

  Mon Aug 26, 2019 07:57
• Microvesicle-mediated delivery of minicircle DNA results in effective gene-directed enzyme prodrug cancer therapy

  An emerging approach for cancer treatment employs the use of extracellular vesicles (EVs), specifically exosomes and microvesicles, as delivery vehicles. We previously demonstrated that microvesicles can functionally deliver plasmid DNA to cells and showed that plasmid size and sequence, in part, determine the delivery efficiency. In this study, delivery vehicles comprised of microvesicles loaded with engineered minicircle (MC) DNA that encodes p

  Molecular Cancer Therapeutics Online First Articles

  Mon Aug 26, 2019 07:57
• Sentinel lymph node biopsy for melanoma of the head and neck: a multicentre study to examine safety, efficacy, and prognostic value

  Sentinel lymph node biopsy (SLNB) is an accurate staging procedure for malignant melanoma but its use in patients with melanoma of the head and neck has been questioned in the past because of a perceived record of poor safety and accuracy. Technical improvements have sought to redress this.Vital structures and variable lymphatic pathways can make its use in the head and neck challenging. In our study we have examined the data and the experiences

  Oral and Maxillofacial Surgery

  Sun Aug 25, 2019 17:00