IJERPH, Vol. 16, Pages 3150: A Citizen Science Approach to Determine Physical Activity Patterns and Demographics of Greenway Users in Winston-Salem, North Carolina International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16173150 Authors: Joshua R. Dilley Justin B. Moore Phillip Summers Amanda A. Price Matthew Burczyk Lynn Byrd Patricia J. Sisson Alain G. Bertoni Citizen science is a growing method of scientific discovery and community...
Thu Aug 29, 2019 03:00
IJERPH, Vol. 16, Pages 3151: Healthy or Unhealthy? The Cocktail of Health-Related Behavior Profiles in Spanish Adolescents International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16173151 Authors: Javier Sevil-Serrano Alberto Aibar-Solana Ángel Abós José Antonio Julián Luis García-González The aim of this study was to identify the prevalence and clustering of health-related behaviors in Spanish adolescents and to examine their association with...
Thu Aug 29, 2019 03:00
IJERPH, Vol. 16, Pages 3152: Enablers and Barriers to the Utilization of Antenatal Care Services in India International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16173152 Authors: Felix Akpojene Ogbo Mansi Vijaybhai Dhami Ebere Maureen Ude Praween Senanayake Uchechukwu L. Osuagwu Akorede O. Awosemo Pascal Ogeleka Blessing Jaka Akombi Osita Kingsley Ezeh Kingsley E. Agho Antenatal care (ANC) reduces adverse health outcomes for both...
Thu Aug 29, 2019 03:00
IJMS, Vol. 20, Pages 4248: Parameters for Optoperforation-Induced Killing of Cancer Cells Using Gold Nanoparticles Functionalized With the C-terminal Fragment of Clostridium Perfringens Enterotoxin International Journal of Molecular Sciences doi: 10.3390/ijms20174248 Authors: Annegret Becker Tina Lehrich Stefan Kalies Alexander Heisterkamp Anaclet Ngezahayo Recently, we used a recombinant produced C-terminus (D194-F319) of the Clostridium perfringens enterotoxin (C-CPE) to...
03:00
IJMS, Vol. 20, Pages 4246: Preeclampsia: Maternal Systemic Vascular Disorder Caused by Generalized Endothelial Dysfunction Due to Placental Antiangiogenic Factors International Journal of Molecular Sciences doi: 10.3390/ijms20174246 Authors: Takuji Tomimatsu Kazuya Mimura Shinya Matsuzaki Masayuki Endo Keiichi Kumasawa Tadashi Kimura Preeclampsia, a systemic vascular disorder characterized by new-onset hypertension and proteinuria after 20 weeks of gestation, is the leading...
03:00
IJMS, Vol. 20, Pages 4247: Fluoxetine Suppresses Glutamate- and GABA-Mediated Neurotransmission by Altering SNARE Complex International Journal of Molecular Sciences doi: 10.3390/ijms20174247 Authors: Vesna Lazarevic Ioannis Mantas Ivana Flais Per Svenningsson Major depressive disorder is one of the most common neuropsychiatric disorders worldwide. The treatment of choice that shows good efficacy in mood stabilization is based on selective serotonin reuptake inhibitors (SSRIs)....
03:00
IJMS, Vol. 20, Pages 4244: Karyotypes and Sex Chromosomes in Two Australian Native Freshwater Fishes, Golden Perch (Macquaria ambigua) and Murray Cod (Maccullochella peelii) (Percichthyidae) International Journal of Molecular Sciences doi: 10.3390/ijms20174244 Authors: Foyez Shams Fiona Dyer Ross Thompson Richard P. Duncan Jason D. Thiem Zuzana Majtánová Tariq Ezaz Karyotypic data from Australian native freshwater fishes are scarce, having been described from relatively...
03:00
IJMS, Vol. 20, Pages 4239: Vine Waste Valorisation: Integrated Approach for the Prospection of Bioactive Lipophilic Phytochemicals International Journal of Molecular Sciences doi: 10.3390/ijms20174239 Authors: Ângelo C. Salvador Mário M. Q. Simões Artur M. S. Silva Sónia A. O. Santos Sílvia M. Rocha Armando J. D. Silvestre Substantial amounts of vine wastes are produced during vineyard management, and the chemical profiling of high-value lipophilic phytochemicals is becoming...
03:00
IJMS, Vol. 20, Pages 4245: Structural Insights into the Interaction of Cytochrome P450 3A4 with Suicide Substrates: Mibefradil, Azamulin and 6′,7′-Dihydroxybergamottin International Journal of Molecular Sciences doi: 10.3390/ijms20174245 Authors: Irina F. Sevrioukova Human cytochrome P450 3A4 (CYP3A4) is the most important drug-metabolizing enzyme. Some drugs and natural compounds can act as suicide (mechanism-based) inactivators of CYP3A4, leading to unanticipated drug-drug interactions,...
03:00
IJMS, Vol. 20, Pages 4242: Wnt/β-Catenin Signaling: The Culprit in Pancreatic Carcinogenesis and Therapeutic Resistance International Journal of Molecular Sciences doi: 10.3390/ijms20174242 Authors: Monish Ram Makena Himavanth Gatla Dattesh Verlekar Sahithi Sukhavasi Manoj K. Pandey Kartick C. Pramanik Pancreatic ductal adenocarcinoma (PDAC) is responsible for 7.3% of all cancer deaths. Even though there is a steady increase in patient survival for most cancers over the...
03:00
IJMS, Vol. 20, Pages 4241: Mast Cell Responses to Viruses and Pathogen Products International Journal of Molecular Sciences doi: 10.3390/ijms20174241 Authors: Jean S. Marshall Liliana Portales-Cervantes Edwin Leong Mast cells are well accepted as important sentinel cells for host defence against selected pathogens. Their location at mucosal surfaces and ability to mobilize multiple aspects of early immune responses makes them critical contributors to effective immunity in several...
03:00
IJMS, Vol. 20, Pages 4238: Cafestol and Kahweol: A Review on Their Bioactivities and Pharmacological Properties International Journal of Molecular Sciences doi: 10.3390/ijms20174238 Authors: Yaqi Ren Chunlan Wang Jiakun Xu Shuaiyu Wang Cafestol and kahweol are natural diterpenes extracted from coffee beans. In addition to the effect of raising serum lipid, in vitro and in vivo experimental results have revealed that the two diterpenes demonstrate multiple potential pharmacological...
03:00
IJMS, Vol. 20, Pages 4240: Omega-3 Docosahexaenoic Acid Is a Mediator of Fate-Decision of Adult Neural Stem Cells International Journal of Molecular Sciences doi: 10.3390/ijms20174240 Authors: Amanda Lo Van Mayssa Hachem Michel Lagarde Nathalie Bernoud-Hubac The mammalian brain is enriched with lipids that serve as energy catalyzers or secondary messengers of essential signaling pathways. Docosahexaenoic acid (DHA) is an omega-3 fatty acid synthesized de novo at low levels in...
03:00
IJMS, Vol. 20, Pages 4236: Cyclin–CDK Complexes are Key Controllers of Capacitation-Dependent Actin Dynamics in Mammalian Spermatozoa International Journal of Molecular Sciences doi: 10.3390/ijms20174236 Authors: Bernabò Ramal-Sanchez Valbonetti Machado-Simoes Ordinelli Capacchietti Taraschi Barboni Mammalian spermatozoa are infertile immediately after ejaculation and need to undergo a functional maturation process to acquire the competence to fertilize the...
Thu Aug 29, 2019 03:00
IJMS, Vol. 20, Pages 4237: Recent Insights from Molecular Dynamics Simulations for G Protein-Coupled Receptor Drug Discovery International Journal of Molecular Sciences doi: 10.3390/ijms20174237 Authors: Zou Ewalt Ng G protein-coupled receptors (GPCRs) are critical drug targets. GPCRs convey signals from the extracellular to the intracellular environment through G proteins. Some ligands that bind to GPCRs activate different downstream signaling pathways. G protein activation,...
Thu Aug 29, 2019 03:00
IJMS, Vol. 20, Pages 4235: Effective Treatment of Metastatic Melanoma by Combining MAPK and PI3K Signaling Pathway Inhibitors International Journal of Molecular Sciences doi: 10.3390/ijms20174235 Authors: Aasen Parajuli Hoang Feng Stokke Wang Roy Bjerkvig Knappskog Thorsen Malignant melanoma is the most aggressive type of skin cancer and is closely associated with the development of brain metastases. Despite aggressive treatment, the prognosis has...
Thu Aug 29, 2019 03:00
IJMS, Vol. 20, Pages 4233: Immunotherapy-Based Targeting and Elimination of Leukemic Stem Cells in AML and CML International Journal of Molecular Sciences doi: 10.3390/ijms20174233 Authors: Peter Valent Irina Sadovnik Gregor Eisenwort Karin Bauer Harald Herrmann Karoline V. Gleixner Axel Schulenburg Werner Rabitsch Wolfgang R. Sperr Dominik Wolf The concept of leukemic stem cells (LSC) has been developed with the idea to explain the clonal hierarchies and architectures...
Thu Aug 29, 2019 03:00
IJMS, Vol. 20, Pages 4234: Xenobiotic Receptors and Their Mates in Atopic Dermatitis International Journal of Molecular Sciences doi: 10.3390/ijms20174234 Authors: Minzaghi Pavel Dubrac Atopic dermatitis (AD) is the most common inflammatory skin disease worldwide. It is a chronic, relapsing and pruritic skin disorder which results from epidermal barrier abnormalities and immune dysregulation, both modulated by environmental factors. AD is strongly associated with asthma and...
Thu Aug 29, 2019 03:00
IJMS, Vol. 20, Pages 4232: New Aspects of Magnesium Function: A Key Regulator in Nucleosome Self-Assembly, Chromatin Folding and Phase Separation International Journal of Molecular Sciences doi: 10.3390/ijms20174232 Authors: Takashi Ohyama Metal cations are associated with many biological processes. The effects of these cations on nucleic acids and chromatin were extensively studied in the early stages of nucleic acid and chromatin research. The results revealed that some monovalent...
Thu Aug 29, 2019 03:00
IJMS, Vol. 20, Pages 4231: Machine Learning to Understand the Immune-Inflammatory Pathways in Fibromyalgia International Journal of Molecular Sciences doi: 10.3390/ijms20174231 Authors: Laura Andrés-Rodríguez Xavier Borràs Albert Feliu-Soler Adrián Pérez-Aranda Antoni Rozadilla-Sacanell Belén Arranz Jesús Montero-Marin Javier García-Campayo Natalia Angarita-Osorio Michael Maes Juan V. Luciano Fibromyalgia (FM) is a chronic syndrome characterized by widespread...
Thu Aug 29, 2019 03:00
IJMS, Vol. 20, Pages 4230: Mechanism of Action of Inhaled Insulin on Whole Body Glucose Metabolism in Subjects with Type 2 Diabetes Mellitus International Journal of Molecular Sciences doi: 10.3390/ijms20174230 Authors: Rucha J. Mehta Amalia Gastaldelli Bogdana Balas Andrea Ricotti Ralph A. DeFronzo Devjit Tripathy In the current study we investigate the mechanisms of action of short acting inhaled insulin Exubera®, on hepatic glucose production (HGP), plasma glucose...
Thu Aug 29, 2019 03:00
IJMS, Vol. 20, Pages 4229: Comparative Quantitative Analysis of Porcine Optic Nerve Head and Retina Subproteomes International Journal of Molecular Sciences doi: 10.3390/ijms20174229 Authors: Sebastian Funke Carsten Schmelter Sascha D. Markowitsch Natarajan Perumal Janis C. Heyne Katharina Bell Norbert Pfeiffer Franz H. Grus Optic nerve head (ONH) and retina (RET) are the main sites of damage in neurodegenerative optic neuropathies including glaucoma. Up to date,...
Thu Aug 29, 2019 03:00
IJMS, Vol. 20, Pages 4228: Development of SpyTag/SpyCatcher-Bacmid Expression Vector System (SpyBEVS) for Protein Bioconjugations Inside of Silkworms International Journal of Molecular Sciences doi: 10.3390/ijms20174228 Authors: Jian Xu Tatsuya Kato Enoch Y. Park Protein conjugations at post-translational levels are known to be essential to protein stability and function. Recently, it has been proven that the split protein CnaB2 (SpyTag/SpyCatcher, ST/SC) from Streptococcus pyogenes...
Thu Aug 29, 2019 03:00
IJMS, Vol. 20, Pages 4227: The Reason for Growth Inhibition of Ulmus pumila ‘Jinye’: Lower Resistance and Abnormal Development of Chloroplasts Slow Down the Accumulation of Energy International Journal of Molecular Sciences doi: 10.3390/ijms20174227 Authors: Lihui Zuo Shuang Zhang Yichao Liu Yinran Huang Minsheng Yang Jinmao Wang Ulmus pumila ‘Jinye’, the colorful leaf mutant of Ulmus pumila L., is widely used in landscaping. In common with most leaf...
Thu Aug 29, 2019 03:00
JCM, Vol. 8, Pages 1346: Physical Activity and Sedentary Behaviour Patterns in 326 Persons with COPD before Starting a Pulmonary Rehabilitation: A Cluster Analysis Journal of Clinical Medicine doi: 10.3390/jcm8091346 Authors: Geidl Carl Cassar Lehbert Mino Wittmann Wagner Schultz Pfeifer This study applies a cluster analysis to identify typical physical activity (PA) and sedentary behaviour (SB) patterns in people with chronic obstructive pulmonary disease...
Thu Aug 29, 2019 03:00
JCM, Vol. 8, Pages 1345: Exosomal miRNAs in Lung Diseases: From Biologic Function to Therapeutic Targets Journal of Clinical Medicine doi: 10.3390/jcm8091345 Authors: Julien Guiot Ingrid Struman Edouard Louis Renaud Louis Michel Malaise Makon-Sébastien Njock Increasing evidence suggests the potential role of extracellular vesicles (EVs) in many lung diseases. According to their subcellular origin, secretion mechanism, and size, EVs are currently classified into three subpopulations:...
Thu Aug 29, 2019 03:00
JCM, Vol. 8, Pages 1342: Inappropriateness of Repeated Laboratory and Radiological Tests for Transferred Emergency Department Patients Journal of Clinical Medicine doi: 10.3390/jcm8091342 Authors: Jérôme Bertrand Christophe Fehlmann Olivier Grosgurin François Sarasin Omar Kherad Background: Laboratory and radiographic tests are often repeated during inter-hospital transfers from secondary to tertiary emergency departments (ED), despite available data from the sending structure....
Thu Aug 29, 2019 03:00
JCM, Vol. 8, Pages 1343: Synovial Cytokines Significantly Correlate with Osteoarthritis-Related Knee Pain and Disability: Inflammatory Mediators of Potential Clinical Relevance Journal of Clinical Medicine doi: 10.3390/jcm8091343 Authors: Timo A. Nees Nils Rosshirt Jiji A. Zhang Tobias Reiner Reza Sorbi Elena Tripel Tilman Walker Marcus Schiltenwolf Sébastien Hagmann Babak Moradi The aim of this study was to identify inflammatory mediators of potential clinical...
Thu Aug 29, 2019 03:00
JCM, Vol. 8, Pages 1340: Podocyte Injury in Lupus Nephritis Journal of Clinical Medicine doi: 10.3390/jcm8091340 Authors: Hamza Sakhi Anissa Moktefi Khedidja Bouachi Vincent Audard Carole Hénique Philippe Remy Mario Ollero Khalil El Karoui Systemic lupus erythematosus (SLE) is characterized by a broad spectrum of renal lesions. In lupus glomerulonephritis, histological classifications are based on immune-complex (IC) deposits and hypercellularity lesions (mesangial...
Thu Aug 29, 2019 03:00
JCM, Vol. 8, Pages 1341: Alpha-1-Antitrypsin Ameliorates Pristane Induced Diffuse Alveolar Hemorrhage in Mice Journal of Clinical Medicine doi: 10.3390/jcm8091341 Authors: Ahmed S. Elshikha Georges Abboud Lonneke van der Meijden-Erkelens Yuanqing Lu Mong-Jen Chen Ye Yuan Godelieva Ponjee Leilani Zeumer Minoru Satoh Laurence Morel Sihong Song Diffuse alveolar hemorrhage (DAH) is a fatal complication in patients with lupus. DAH can be induced in B6 mice by...
Thu Aug 29, 2019 03:00
JCM, Vol. 8, Pages 1338: Platelet-Activating Factor (PAF) in Allergic Rhinitis: Clinical and Therapeutic Implications Journal of Clinical Medicine doi: 10.3390/jcm8091338 Authors: Rosa M. Muñoz-Cano Rocio Casas-Saucedo Antonio Valero Santiago Irina Bobolea Paula Ribó Joaquim Mullol Platelet-activating factor (PAF) is a lipid mediator involved in several allergic reactions. It is released from multiple cells of the immune system, such as eosinophils, neutrophils, and mast...
Thu Aug 29, 2019 03:00
JCM, Vol. 8, Pages 1344: Correlation between Sleep Bruxism, Stress, and Depression—A Polysomnographic Study Journal of Clinical Medicine doi: 10.3390/jcm8091344 Authors: Joanna Smardz Helena Martynowicz Anna Wojakowska Monika Michalek-Zrabkowska Grzegorz Mazur Mieszko Wieckiewicz Background and objectives: Sleep bruxism is a common phenomenon that can affect approximately 13% of adult population. It is estimated that bruxism can be caused by three types of factors: biological,...
Thu Aug 29, 2019 03:00
JCM, Vol. 8, Pages 1337: Real World Patterns of Antimicrobial Use and Microbiology Investigations in Patients with Sepsis outside the Critical Care Unit: Secondary Analysis of Three Nation-Wide Point Prevalence Studies Journal of Clinical Medicine doi: 10.3390/jcm8091337 Authors: Maja Kopczynska Ben Sharif Harry Unwin John Lynch Andrew Forrester Claudia Zeicu Sian Cleaver Svetlana Kulikouskaya Tom Chandy Eshen Ang Emily Murphy Umair Asim Bethany Payne Jessica...
Thu Aug 29, 2019 03:00
JCM, Vol. 8, Pages 1339: Importance of Virulence Factors for the Persistence of Oral Bacteria in the Inflamed Gingival Crevice and in the Pathogenesis of Periodontal Disease Journal of Clinical Medicine doi: 10.3390/jcm8091339 Authors: Gunnar Dahlen Amina Basic Johan Bylund Periodontitis is a chronic inflammation that develops due to a destructive tissue response to prolonged inflammation and a disturbed homeostasis (dysbiosis) in the interplay between the microorganisms of the...
Thu Aug 29, 2019 03:00
JCM, Vol. 8, Pages 1336: Predicting Cardiac Arrest and Respiratory Failure Using Feasible Artificial Intelligence with Simple Trajectories of Patient Data Journal of Clinical Medicine doi: 10.3390/jcm8091336 Authors: Jeongmin Kim Myunghun Chae Hyuk-Jae Chang Young-Ah Kim Eunjeong Park We introduce a Feasible Artificial Intelligence with Simple Trajectories for Predicting Adverse Catastrophic Events (FAST-PACE) solution for preparing immediate intervention in emergency situations....
Thu Aug 29, 2019 03:00
J. Imaging, Vol. 5, Pages 72: Improvement of the Non-Destructive Testing of Heritage Mural Paintings Using Stimulated Infrared Thermography and Frequency Image Processing Journal of Imaging doi: 10.3390/jimaging5090072 Authors: Kamel Mouhoubi Vincent Detalle Jean-Marc Vallet Jean-Luc Bodnar Within the framework of conservation and assistance for the restoration of cultural property, a method of analysis assistance has been developed to help in the restoration of cultural heritage....
Thu Aug 29, 2019 03:00
Medical Sciences, Vol. 7, Pages 91: A Review of Current and Emerging Therapeutic Options for Erectile Dysfunction Medical Sciences doi: 10.3390/medsci7090091 Authors: Chung Contemporary treatment algorithms for erectile dysfunction (ED) involve the use of medical therapies such as phosphodiesterase type 5 (PDE5) inhibitors and intracavernosal injection therapy of vasoactive agents, as well as vacuum erection devices and penile prosthesis implants in medically refractory cases. However,...
Thu Aug 29, 2019 03:00
Medical Sciences, Vol. 7, Pages 90: Erectile Dysfunction: A Primer for in Office Management Medical Sciences doi: 10.3390/medsci7090090 Authors: Samir Sami Noah Stern Andrew Di Pierdomenico Brandon Katz Gerald Brock Introduction: Optimizing erectile dysfunction (ED) remains a clinically significant endeavor as insufficient outcomes from oral, injectable and even surgical approaches to treatment remain less than ideal. In this report, we integrate evolving knowledge and provide...
Thu Aug 29, 2019 03:00
Medicina, Vol. 55, Pages 547: Total Serum Magnesium Levels and Calcium-To-Magnesium Ratio in Sickle Cell Disease Medicina doi: 10.3390/medicina55090547 Authors: Antwi-Boasiako Kusi-Mensah Hayfron-Benjamin Aryee Dankwah Kwawukume Darkwa Background and objectives: Imbalance of calcium/magnesium ratio could lead to clinical complications in sickle cell disease (SCD). Low levels of magnesium have been associated with sickling, increased polymerization and vaso-occlusion...
Thu Aug 29, 2019 03:00
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου