Medicina, Vol. 55, Pages 526: Hepatocellular Carcinoma: Molecular Mechanisms and Targeted Therapies Medicina doi: 10.3390/medicina55090526 Authors: Alqahtani Khan Alloghbi Said Ahmed Ashraf Hammouda Hepatocellular carcinoma (HCC) is one of the most common and lethal malignant tumors worldwide. HCC is a complex process that is associated with several etiological factors, which in turn result in aberrant activation of different cellular and molecular pathways and the...
Fri Aug 23, 2019 03:00
Medicina, Vol. 55, Pages 527: The Significance of Endometrial Scratching for Clinical Pregnancy Rate in Long Agonist and Antagonist Protocols Medicina doi: 10.3390/medicina55090527 Authors: Rimantas Gricius Greta Balciuniene Lina Jakubauskiene Diana Ramasauskaite Background and Objectives: Assisted reproductive techniques today have helped many infertile couples achieve their desired pregnancy. However, unsuccessful implantation is usually the key failure in in vitro fertilization...
Fri Aug 23, 2019 03:00
Medicina, Vol. 55, Pages 525: Use of Medicinal Cannabis and Synthetic Cannabinoids in Post-Traumatic Stress Disorder (PTSD): A Systematic Review Medicina doi: 10.3390/medicina55090525 Authors: Orsolini Chiappini Volpe Berardis Latini Papanti Corkery Background and Objectives: Post-traumatic stress disorder (PTSD) is a common psychiatric disorder resulting from a traumatic event, is manifested through hyperarousal, anxiety, depressive symptoms, and sleep disturbances....
Fri Aug 23, 2019 03:00
Medicina, Vol. 55, Pages 524: Somatosensory and Motor Differences between Physically Active Patients with Chronic Low Back Pain and Asymptomatic Individuals Medicina doi: 10.3390/medicina55090524 Authors: Juan Nieto-García Luis Suso-Martí Roy La Touche Mónica Grande-Alonso Background and Objectives: Chronic low back pain (CLBP) is the most common occupational disorder due to its associated disability and high risk of recurrence and chronicity. However, the mechanisms underlying...
Fri Aug 23, 2019 03:00
Medicina, Vol. 55, Pages 523: Pancreatic Polypeptide-Secreting Tumour of the Proximal Pancreas (PPoma)—Ultra Rare Pancreatic Tumour: Clinically Malign, Histologically Benign Medicina doi: 10.3390/medicina55090523 Authors: Ivan Ilić Vuka Katić Pavle Randjelović Nikola Stojanović Aleksandra Antovic Ratko Ilić Background and objectives: Here we report a rare case of a pancreatic polypeptide-secreting tumour (PPoma) discovered by accident during an autopsy. These PPomas occur...
Fri Aug 23, 2019 03:00
Medicina, Vol. 55, Pages 522: Opioids Preconditioning Upon Renal Function and Ischemia-Reperfusion Injury: A Narrative Review Medicina doi: 10.3390/medicina55090522 Authors: Julio Palomino Raquel Echavarria Adriana Franco-Acevedo Bibiana Moreno-Carranza Zesergio Melo Kidneys have an important role in regulating water volume, blood pressure, secretion of hormones and acid-base and electrolyte balance. Kidney dysfunction derived from acute injury can, under certain conditions,...
Fri Aug 23, 2019 03:00
Membranes, Vol. 9, Pages 108: Ceria-Based Dual-Phase Membranes for High-Temperature Carbon Dioxide Separation: Effect of Iron Doping and Pore Generation with MgO Template Membranes doi: 10.3390/membranes9090108 Authors: Gili Bischoff Simon Schmidt Kober Görke Bekheet Gurlo Dual-phase membranes for high-temperature carbon dioxide separation have emerged as promising technology to mitigate anthropogenic greenhouse gases emissions, especially as a pre- and post-combustion...
Mon Aug 26, 2019 03:00
MPs, Vol. 2, Pages 74: An Assay to Study Intra-Chromosomal Deletions in Yeast Methods and Protocols doi: 10.3390/mps2030074 Authors: Bailey E. Lucas Matthew T. McPherson Tila M. Hawk Lexia N. Wilson Jacob M. Kroh Kyle G. Hickman Sean R. Fitzgerald W. Miguel Disbennett P. Daniel Rollins Hannah M. Hylton Mohammed A. Baseer Paige N. Montgomery Jian-Qiu Wu Ruben C. Petreaca An accurate DNA damage response pathway is critical for the repair of DNA double-strand...
Mon Aug 26, 2019 03:00
Microorganisms, Vol. 7, Pages 292: A Coordinated Response at The Transcriptome and Interactome Level is Required to Ensure Uropathogenic Escherichia coli Survival during Bacteremia Microorganisms doi: 10.3390/microorganisms7090292 Authors: Natalia Sanchez de Groot Marc Torrent Burgas Localized infections or disruption of the skin barrier can enable the entry of bacteria into the bloodstream, possibly leading to acute inflammation and sepsis. There is currently no holistic view on...
Sun Aug 25, 2019 03:00
Microorganisms, Vol. 7, Pages 291: Polyphasic, Including MALDI-TOF MS, Evaluation of Freeze-Drying Long-Term Preservation on Aspergillus (Section Nigri) Strains Microorganisms doi: 10.3390/microorganisms7090291 Authors: Rodrigo Rodriguez Carla Santos Marta F. Simões Célia Soares Cledir Santos Nelson Lima This study aims to evaluate the effect of freeze-drying and long-term storage on the biotechnological potential of Aspergillus section Nigri strains. Twelve selected strains...
Sun Aug 25, 2019 03:00
Microorganisms, Vol. 7, Pages 290: A Transcriptional Activator of Ascorbic Acid Transport in Streptococcus pneumoniae Is Required for Optimal Growth in Endophthalmitis in a Strain-Dependent Manner Microorganisms doi: 10.3390/microorganisms7090290 Authors: Angela H. Benton Mary Darby Jackson Sandy M. Wong Justine L. Dees Brian J. Akerley Mary E. Marquart Streptococcus pneumoniae is among the top causes of bacterial endophthalmitis, an infectious disease of the intraocular...
Sat Aug 24, 2019 03:00
Microorganisms, Vol. 7, Pages 289: Arbuscular Mycorrhiza Enhances Biomass Production and Salt Tolerance of Sweet Sorghum Microorganisms doi: 10.3390/microorganisms7090289 Authors: Wang Sun Shi Arbuscular mycorrhizal (AM) fungi (AMF) are widely known to form a symbiosis with most higher plants and enhance plant adaptation to a series of environmental stresses. Sweet sorghum (Sorghum bicolor (L.) Moench) is considered a promising alternative feedstock for bioalcohol production...
Fri Aug 23, 2019 03:00
Microorganisms, Vol. 7, Pages 288: Omics Analysis for Dinoflagellates Biology Research Microorganisms doi: 10.3390/microorganisms7090288 Authors: Bi Wang Zhang Dinoflagellates are important primary producers for marine ecosystems and are also responsible for certain essential components in human foods. However, they are also notorious for their ability to form harmful algal blooms, and cause shellfish poisoning. Although much work has been devoted to dinoflagellates in recent...
Fri Aug 23, 2019 03:00
Microorganisms, Vol. 7, Pages 287: Does Soil Contribute to the Human Gut Microbiome? Microorganisms doi: 10.3390/microorganisms7090287 Authors: Winfried E.H. Blum Sophie Zechmeister-Boltenstern Katharina M. Keiblinger Soil and the human gut contain approximately the same number of active microorganisms, while human gut microbiome diversity is only 10% that of soil biodiversity and has decreased dramatically with the modern lifestyle. We tracked relationships between the soil microbiome...
Fri Aug 23, 2019 03:00
Microorganisms, Vol. 7, Pages 286: Efficiency of Phage φ6 for Biocontrol of Pseudomonas syringae pv. syringae: An in Vitro Preliminary Study Microorganisms doi: 10.3390/microorganisms7090286 Authors: Larindja A. M. Pinheiro Carla Pereira Carolina Frazão Victor M. Balcão Adelaide Almeida Pseudomonas syringae is a plant-associated bacterial species that has been divided into more than 60 pathovars, with the Pseudomonas syringae pv. syringae being the main causative agent of...
Fri Aug 23, 2019 03:00
Molecules, Vol. 24, Pages 3105: The Influence of Essential Oil Compounds on Antibacterial Activity of Mupirocin-Susceptible and Induced Low-Level Mupirocin-Resistant MRSA Strains Molecules doi: 10.3390/molecules24173105 Authors: Paweł Kwiatkowski Agata Pruss Bartosz Wojciuk Barbara Dołęgowska Anna Wajs-Bonikowska Monika Sienkiewicz Monika Mężyńska Łukasz Łopusiewicz Because of the bacterial drug resistance development, it is reasonable to investigate chemical compounds...
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Molecules, Vol. 24, Pages 3104: Levels of Furaneol in Msalais Wines: A Comprehensive Overview of Multiple Stages and Pathways of Its Formation during Msalais Winemaking Molecules doi: 10.3390/molecules24173104 Authors: Li-Xia Zhu Meng-Meng Zhang Zheng Liu Yin Shi Chang-Qing Duan 4-Hydroxy-2,5-dimethyl-3(2H)-furanone (furaneol) is present in food. It has a caramel-like flavor, which affects the quality of food, and is formed via multiple pathways. Msalais is a traditional...
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Molecules, Vol. 24, Pages 3103: Hypoglycemic, Antiglycation, and Cytoprotective Properties of a Phenol-Rich Extract From Waste Peel of Punica granatum L. var. Dente di Cavallo DC2 Molecules doi: 10.3390/molecules24173103 Authors: Antonella Di Sotto Marcello Locatelli Alberto Macone Chiara Toniolo Stefania Cesa Simone Carradori Margherita Eufemi Gabriela Mazzanti Silvia Di Giacomo Pomegranate peel is a natural source of phenolics, claimed to possess healing properties,...
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Molecules, Vol. 24, Pages 3102: A 7-Hydroxybenzoxazinone-Containing Fluorescence Turn-On Probe for Biothiols and Its Bioimaging Applications Molecules doi: 10.3390/molecules24173102 Authors: Bin Li Datong Zhang Ruibing An Yaling Zhu In this work, a novel 7-hydroxybenzoxazinone-based fluorescent probe (PBD) for the selective sensing of biothiols is reported. Upon treatment with biothiols, PBD shows a strong fluorescence enhancement (up to 70-fold) and a large Stokes shift (155...
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Molecules, Vol. 24, Pages 3100: A Green Water-Soluble Cyclophosphazene as a Flame Retardant Finish for Textiles Molecules doi: 10.3390/molecules24173100 Authors: Mayer-Gall Plohl Derksen Lauer Neldner Ali Fuchs Gutmann Opwis Poly- and cyclophosphazenes are excellent flame retardants but currently, are not used as textile finishing agents because water-soluble and permanent washing systems are missing. Here, we demonstrate for the first time, the successful...
Mon Aug 26, 2019 03:00
Molecules, Vol. 24, Pages 3099: Prediction of Disease-related microRNAs through Integrating Attributes of microRNA Nodes and Multiple Kinds of Connecting Edges Molecules doi: 10.3390/molecules24173099 Authors: Xuan Li Zhang Zhang Song Identifying disease-associated microRNAs (disease miRNAs) contributes to the understanding of disease pathogenesis. Most previous computational biology studies focused on multiple kinds of connecting edges of miRNAs and diseases, including...
Mon Aug 26, 2019 03:00
Molecules, Vol. 24, Pages 3101: Phytochemical Profile and Antimicrobial Potential of Extracts Obtained from Thymus marschallianus Willd Molecules doi: 10.3390/molecules24173101 Authors: Niculae Hanganu Oniga Benedec Ielciu Giupana Sandru Ciocârlan Spinu Thymus marschallianus Willd. is a Lamiaceae species spread in a large variety of habitats worldwide. The aim of the present research was to analyse two different samples belonging to this species, one...
Mon Aug 26, 2019 03:00
Molecules, Vol. 24, Pages 3097: Optimization of Membrane Electrode Assembly of PEM Fuel Cell by Response Surface Method Molecules doi: 10.3390/molecules24173097 Authors: Vuppala Chedir Jiang Chen Aziz Sasmito The membrane electrode assembly (MEA) plays an important role in the proton exchange membrane fuel cell (PEMFC) performance. Typically, the structure comprises of a polymer electrolyte membrane sandwiched by agglomerate catalyst layers at the anode and cathode....
Mon Aug 26, 2019 03:00
Molecules, Vol. 24, Pages 3096: SAR by Space: Enriching Hit Sets from the Chemical Space Molecules doi: 10.3390/molecules24173096 Authors: Klingler Gastreich Grygorenko Savych Borysko Griniukova Gubina Lemmen Moroz We introduce SAR-by-Space, a concept to drastically accelerate structure-activity relationship (SAR) elucidation by synthesizing neighboring compounds that originate from vast chemical spaces. The space navigation is accomplished within minutes...
Mon Aug 26, 2019 03:00
Molecules, Vol. 24, Pages 3098: Synthesis, Structure, and Reactivity of Binaphthyl Supported Dihydro[1,6]diazecines Molecules doi: 10.3390/molecules24173098 Authors: Lemmerer Abraham Brutiu Roller Widhalm A short approach to chiral diaza-olefines from protected 2,2′-diamino-1,1′-binaphthyl is presented. Cis- and trans-olefines can be selectively obtained by twofold N-allylation followed by RCM or by bridging a 2,2′-diamino-1,1′-binaphthyl...
Mon Aug 26, 2019 03:00
Molecules, Vol. 24, Pages 3094: Anti-Inflammatory Effects of Phenolic Compounds Isolated from Quercus Mongolica Fisch. ex Ledeb. on UVB-Irradiated Human Skin Cells Molecules doi: 10.3390/molecules24173094 Authors: Jun Yin Han Hyuk Kim In Hyeok Hwang Dong Hee Kim Min Won Lee Quercus mongolica Fisch. ex Ledeb. (QM) has been used as an oriental traditional medicine to relieve hemorrhoids, fever, and enteritis. We screened the inhibitory activities of the extracts and compounds...
Mon Aug 26, 2019 03:00
Molecules, Vol. 24, Pages 3093: A New Fluorescent Chemosensor for Cobalt(II) Ions in Living Cells Based on 1,8-Naphthalimide Molecules doi: 10.3390/molecules24173093 Authors: Yu-Long Liu Liu Yang Lu Li You-Quan Guo Xiao-Xiao Pang Ping Li Fei Ye Ying Fu In this work, a highly selective fluorescent chemosensor N-(2-(2-butyl-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinolin-6-yl)hydrazine-1-carbonothioyl)benzamide (L) was prepared and characterized. An assay to detect the...
Mon Aug 26, 2019 03:00
Molecules, Vol. 24, Pages 3095: Antibacterial and Antispore Activities of Isolated Compounds from Piper cubeba L. Molecules doi: 10.3390/molecules24173095 Authors: Alqadeeri Rukayadi Abbas Shaari Piper cubeba L. is the berry of a shrub that is indigenous to Java, Southern Borneo, Sumatra, and other islands in the Indian Ocean. The plant is usually used in folk traditional medicine and is an important ingredient in cooking. The purpose of this study was to isolate and purify...
Mon Aug 26, 2019 03:00
Molecules, Vol. 24, Pages 3092: The Effect of Tartary Buckwheat Flavonoids in Inhibiting the Proliferation of MGC80-3 Cells during Seed Germination Molecules doi: 10.3390/molecules24173092 Authors: Xiao-Li Zhou Zhi-Dong Chen Yi-Ming Zhou Rong-Hua Shi Zong-Jie Li Tartary buckwheat (Fagopyrum tataricum (L.) Gaertn) is rich in functional compounds such as rutin, quercetin, d-chiro-inositol, dietary fiber, and essential amino acids. Electric field (EF) treatment before sprout...
Mon Aug 26, 2019 03:00
Molecules, Vol. 24, Pages 3091: Determination of Volatile Compounds in Nut-Based Milk Alternative Beverages by HS-SPME Prior to GC-MS Analysis Molecules doi: 10.3390/molecules24173091 Authors: Natalia Manousi George A. Zachariadis A reliable Headspace-Solid Phase Microextraction (HS-SPME) method was developed for the determination of polar volatile components of commercial nut-based milk alternative drinks prior to Gas Chromatography–Mass Spectrometry (GC-MS) analysis. Under...
Mon Aug 26, 2019 03:00
Molecules, Vol. 24, Pages 3090: Characterization of Polysulfides, Polysulfanes, and Other Unique Species in the Reaction between GSNO and H2S Molecules doi: 10.3390/molecules24173090 Authors: Murugaeson R Kumar Patrick J Farmer Glutathione-based products, GSnX, of the reaction of hydrogen sulfide, H2S, S-nitroso glutathione, and GSNO, at varied stoichiometries have been analyzed by liquid chromatography high-resolution mass spectrometry (LC-HRMS) and chemical trapping experiments....
Mon Aug 26, 2019 03:00
Molecules, Vol. 24, Pages 3089: Editorial to the Special Issue—“Recent Advances in Self-Assembled Peptides” Molecules doi: 10.3390/molecules24173089 Authors: He Dong Peptide self-assembly is an interdisciplinary research area involving chemistry, life science, and materials science [...]
Mon Aug 26, 2019 03:00
Molecules, Vol. 24, Pages 3088: Evaluation of Tryptic Podocin Peptide in Urine Sediment Using LC-MS-MRM Method as a Potential Biomarker of Glomerular Injury in Dogs with Clinical Signs of Renal and Cardiac Disorders Molecules doi: 10.3390/molecules24173088 Authors: Barbara Szczepankiewicz Remigiusz Bąchor Robert Pasławski Natalia Siwińska Urszula Pasławska Andrzej Konieczny Zbigniew Szewczuk The early asymptomatic stage of glomerular injury is a diagnostic challenge...
Mon Aug 26, 2019 03:00
Molecules, Vol. 24, Pages 3087: Romanian Wormwood (Artemisia absinthium L.): Physicochemical and Nutraceutical Screening Molecules doi: 10.3390/molecules24173087 Authors: Moacă Pavel Danciu Crăiniceanu Minda Ardelean Antal Ghiulai Cioca Derban Simu Chioibaş Szuhanek Dehelean Artemisia species are used worldwide for their antioxidant, antimicrobial and anti-inflammatory properties. This research was designed to investigate the phytochemical...
Sun Aug 25, 2019 03:00
Molecules, Vol. 24, Pages 3085: The Entrapment of Somatostatin in a Lipid Formulation: Retarded Release and Free Radical Reactivity Molecules doi: 10.3390/molecules24173085 Authors: Anna Larocca Gianluca Toniolo Silvia Tortorella Marios Krokidis Georgia Menounou Giuseppe Di Bella Chryssostomos Chatgilialoglu Carla Ferreri The natural peptide somatostatin has hormonal and cytostatic effects exerted by the binding to specific receptors in various tissues. Therapeutic...
Sun Aug 25, 2019 03:00
Molecules, Vol. 24, Pages 3086: Synthesis of Novel 2-(Het)arylpyrrolidine Derivatives and Evaluation of Their Anticancer and Anti-Biofilm Activity Molecules doi: 10.3390/molecules24173086 Authors: Andrey Smolobochkin Almir Gazizov Marina Sazykina Nurgali Akylbekov Elena Chugunova Ivan Sazykin Anastasiya Gildebrant Julia Voronina Alexander Burilov Shorena Karchava Maria Klimova Alexandra Voloshina Anastasia Sapunova Elena Klimanova Tatyana Sashenkova...
Sun Aug 25, 2019 03:00
Molecules, Vol. 24, Pages 3083: Chemical Composition, Antioxidant and Cytotoxicity Activities of Leaves, Bark, Twigs and Oleo-Resin of Dipterocarpus alatus Molecules doi: 10.3390/molecules24173083 Authors: Chawalit Yongram Bunleu Sungthong Ploenthip Puthongking Natthida Weerapreeyakul Dipterocarpus alatus (Dipterocarpaceae) is a medicinal plant whose use is well known for the treatment of genito-urinary diseases. However, there is no report of its cytotoxic potential. In this...
Sun Aug 25, 2019 03:00
Molecules, Vol. 24, Pages 3084: Melatonin Inhibits Apoptosis and Oxidative Stress of Mouse Leydig Cells via a SIRT1-Dependent Mechanism Molecules doi: 10.3390/molecules24173084 Authors: Gaoqing Xu Jing Zhao Hongyu Liu Jun Wang Wenfa Lu The purpose of the present study is to examine the effects of melatonin on apoptosis and oxidative stress in mouse Leydig cells and to elucidate the mechanisms responsible for these effects. Our results indicated that 10 ng/mL of melatonin...
Sun Aug 25, 2019 03:00
Molecules, Vol. 24, Pages 3081: Plant Leucine-Rich Repeat Receptor Kinase (LRR-RK): Structure, Ligand Perception, and Activation Mechanism Molecules doi: 10.3390/molecules24173081 Authors: Sayan Chakraborty Brian Nguyen Syed Danyal Wasti Guozhou Xu In recent years, secreted peptides have been recognized as essential mediators of intercellular communication which governs plant growth, development, environmental interactions, and other mediated biological responses, such as stem...
Sun Aug 25, 2019 03:00
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