Related ArticlesPharmacogenetics of medication-related osteonecrosis of the jaw: a systematic review and meta-analysis. Int J Oral Maxillofac Surg. 2019 Aug 21;: Authors: Guo Z, Cui W, Que L, Li C, Tang X, Liu J Abstract Medication-related osteonecrosis of the jaw (MRONJ) is a severe complication that can develop in patients treated with anti-resorptive drugs. Although the pathogenesis of MRONJ is still unclear, genetic factors have a demonstrated important...
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Related ArticlesDown-regulation of hsa_circ_0092125 is related to the occurrence and development of oral squamous cell carcinoma. Int J Oral Maxillofac Surg. 2019 Aug 16;: Authors: Gao L, Wang QB, Zhi Y, Ren WH, Li SM, Zhao CY, Xing XM, Dou ZC, Liu JC, Jiang CM, Zhi KQ Abstract Circular RNA plays an important role in regulating tumour development and progression and can serve as a biomarker for cancer. This study was performed to investigate the clinical...
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Related ArticlesLetter to editor: Misleading conclusions in the recently published study by Taito et al. "Voice rehabilitation for laryngeal cancer after radiotherapy: a systematic review and meta-analysis". Eur Arch Otorhinolaryngol. 2019 Aug 24;: Authors: Karlsson T, Johansson M, Andrell P, Finizia C PMID: 31446469 [PubMed - as supplied by publisher]
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Related ArticlesIs voice rehabilitation not necessary for patients with laryngeal cancer after radiotherapy? Eur Arch Otorhinolaryngol. 2019 Aug 24;: Authors: Huang GJ, Yang BB PMID: 31446468 [PubMed - as supplied by publisher]
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Related ArticlesWireless inertial measurement unit (IMU)-based posturography. Eur Arch Otorhinolaryngol. 2019 Aug 23;: Authors: Valldeperes A, Altuna X, Martinez-Basterra Z, Rossi-Izquierdo M, Benitez-Rosario J, Perez-Fernandez N, Rey-Martinez J Abstract BACKGROUND: Classical posturography techniques have been recently enhanced by the use of different motion tracking devices, but for technical reasons they are not used to track directly the body spatial...
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Related ArticlesImmunohistochemical analysis of MMP-13 and EMMPRIN in epithelial odontogenic lesions. Eur Arch Otorhinolaryngol. 2019 Aug 22;: Authors: de Andrade Santos PP, Nonaka CFW, Barboza CAG, Pereira Pinto L, de Souza LB Abstract PURPOSE: To investigate the contribution of MMP-13 in tumor aggressiveness, by acting on the reorganization of the extracellular matrix, regulating the biological activity of cytokines in odontogenic epithelial lesions,...
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Related ArticlesClinical characteristics of acinic cell carcinoma and secretory carcinoma of the parotid gland. Eur Arch Otorhinolaryngol. 2019 Aug 22;: Authors: Terada T, Kawata R, Noro K, Higashino M, Nishikawa S, Haginomori SI, Kurisu Y, Kuwabara H, Hirose Y Abstract PURPOSE: Mammary analogue secretory carcinoma (SC) of the parotid gland is a relatively uncommon cancer associated with the ETV6-NTRK3 fusion product similar to breast cancer. The clinical...
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Related ArticlesMorphometric examination of the styloid process by 3D-CT in patients with Eagle syndrome. Eur Arch Otorhinolaryngol. 2019 Aug 21;: Authors: Ayyildiz VA, Senel FA, Dursun A, Ozturk K Abstract PURPOSE: This study aimed to obtain the length, medial-anterior angulation and basis-apex coordinates of the styloid process in patients with Eagle syndrome by three-dimensional computed tomography. METHODS: This study was performed on three-dimensional...
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Related ArticlesStapes surgery leads to significant improvement in quality of life, independently from the surgical method: evaluation of stapes surgery using different prostheses and different quality of life measurements. Eur Arch Otorhinolaryngol. 2019 Aug 19;: Authors: Weiss NM, Schuldt S, Großmann W, Oberhoffner T, Ginzkey C, Schraven SP, Mlynski R Abstract OBJECTIVES: To compare quality-of-life (QoL) measurements with audiological results after...
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Related ArticlesEffects of pentoxifylline and tocopherol on a rat-irradiated jaw model using micro-CT cortical bone analysis. Eur Arch Otorhinolaryngol. 2019 Aug 14;: Authors: Nguyen TTH, Eo MY, Seo MH, Myoung H, Kim SM, Lee JH Abstract PURPOSE: A combination of pentoxifylline (PTX) and tocopherol (TP) is believed to reduce chronic fibrosis and induce bone healing in osteoradionecrosis (ORN) of the mandible, but evidence of its therapeutic effectiveness...
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Related ArticlesExploring stimulation patterns for electrical stimulation of the larynx using surface electrodes. Eur Arch Otorhinolaryngol. 2019 Aug 14;: Authors: Feiner M, Gerstenberger C, Mayr W, Hortobagyi D, Gugatschka M Abstract PURPOSE: Functional electrical stimulation (FES) is considered an upcoming treatment modality for a number of laryngeal diseases. However, sound data are scarce when it comes to surface FES to treat voice disorders. Aim...
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Related ArticlesDysphagia following uncomplicated thyroidectomy: a systematic review. Eur Arch Otorhinolaryngol. 2019 Aug 14;: Authors: Galluzzi F, Garavello W Abstract OBJECTIVE: Dysphagia after uncomplicated thyroidectomy is commonly reported and it includes a broad spectrum of swallowing complaints. Though various causes have been hypothesized, it remains not completely understood. METHODS: A systematic review was performed to identify studies...
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Related ArticlesEfficacy of hemithyroidectomy in papillary thyroid carcinoma with minimal extrathyroidal extension. Eur Arch Otorhinolaryngol. 2019 Aug 14;: Authors: Ji YB, Song CM, Kim D, Sung ES, Lee DW, Chung MS, Tae K Abstract PURPOSE: This study aimed to compare the oncologic outcomes of hemithyroidectomy with total thyroidectomy in clinically node-negative (cN0) papillary thyroid carcinoma (PTC) with minimal extrathyroidal extension (ETE). ...
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Related ArticlesIs there a relation between sudden sensorineural hearing loss and white matter lesions? Eur Arch Otorhinolaryngol. 2019 Aug 13;: Authors: Fusconi M, Attanasio G, Capitani F, Di Porto E, Diacinto D, Musy I, Ralli M, Ralli G, Greco A, de Vincentiis M, Colonnese C Abstract PURPOSE: Sudden sensorineural hearing loss (SSNHL) has similarities to conditions with vascular etiologies such as myocardial infarction and cerebral stroke. Thus, it...
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Related ArticlesPretreatment low prognostic nutritional index and low albumin-globulin ratio are predictive for overall survival in nasopharyngeal cancer. Eur Arch Otorhinolaryngol. 2019 Aug 10;: Authors: Gundog M, Basaran H Abstract PURPOSE: We designed this retrospective study to identify predictive value of prognostic nutritional index (PNI) and albumin-globulin ratio (AGR) in nasopharyngeal cancer patients (NPC). METHODS: 95 non-metastatic...
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Related ArticlesComparison of prognostic implications between the 7th and 8th edition of AJCC TNM staging system for head and neck soft-tissue sarcoma in adult patients. Eur Arch Otorhinolaryngol. 2019 Aug 09;: Authors: Kim H, Choi N, Baek CH, Son YI, Jeong HS, Chung MK Abstract PURPOSE: This study aimed to investigate the prognostic factors for head and neck soft-tissue sarcoma (HNSTS) in adults, with the comparisons between the 7th and 8th edition...
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Publication date: Available online 26 August 2019Source: Materials & DesignAuthor(s): Ting-Ting Li, Wenna Dai, Shih-Yu Huang, Hongyang Wang, Qi Lin, Ching-Wen Lou, Jia-Horng LinAbstractThis study constructs a flexible gradient foaming structure by changes the maleic anhydride-grafted styrene-ethylene/butylene-styrene (SEBS-g-MAH) content on the basis of a two-step foaming technique. The effects of SEBS-g-MAH content and its ratio in the first and second foaming steps on microstructure, compression,...
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Publication date: Available online 26 August 2019Source: Materials & DesignAuthor(s): Jerzy SmardzewskiAbstractWood consumption is constantly being rationalized by the production of modern wood-based materials, especially honeycomb plates. Due to the beneficial properties of the auxetics, wooden honeycomb panels with auxetic cores can be used as structural elements. In particularly as walls and partitions in wooden houses, as well as shelves and bodies for cabinet furniture. Thus the aim of this...
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Publication date: Available online 26 August 2019Source: Materials & DesignAuthor(s): Qinghua Wei, Xianxuan Cai, Yuhong Guo, Guowei Wang, Ying Guo, Mingju Lei, Yao Song, Zhang Yingfeng, Yanen WangAbstractAs one of the most promising biodegradable material, poly(lactic acid) (PLA) is widely used for 3D printing bone scaffolds. However, the inflammation resulted by the intermediate product (lactic acid) of PLA degradation and poor cell affinity still pose a challenge. Blending PLA with o-carboxymethyl...
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Publication date: Available online 26 August 2019Source: Materials & DesignAuthor(s): Maria Wątroba, Wiktor Bednarczyk, Jakub Kawałko, Krzysztof Mech, Marianna Marciszko, Gabriela Boelter, Manuel Banzhaf, Piotr BałaAbstractIn this study, a new biodegradable alloy from the Zn-Ag-Zr system was investigated. Most importantly, mechanical properties and ductility were significantly improved in designed Zn1Ag0.05Zr alloy in comparison to binary Zn1Ag and previously investigated Zn0.05Zr alloys (wt%)....
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Publication date: 22 August 2019Source: Cell, Volume 178, Issue 5Author(s): Matthew B. Dong, Guangchuan Wang, Ryan D. Chow, Lupeng Ye, Lvyun Zhu, Xiaoyun Dai, Jonathan J. Park, Hyunu R. Kim, Youssef Errami, Christopher D. Guzman, Xiaoyu Zhou, Krista Y. Chen, Paul A. Renauer, Yaying Du, Johanna Shen, Stanley Z. Lam, Jingjia J. Zhou, Donald R. Lannin, Roy S. Herbst, Sidi ChenSummaryCD8 T cells play essential roles in anti-tumor immune responses. Here, we performed genome-scale CRISPR screens in CD8...
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Publication date: 22 August 2019Source: Cell, Volume 178, Issue 5Author(s): Kathrin Jaeger, Steffen Bruenle, Tobias Weinert, Wolfgang Guba, Jonas Muehle, Takuya Miyazaki, Martin Weber, Antonia Furrer, Noemi Haenggi, Tim Tetaz, Chia-Ying Huang, Daniel Mattle, Jean-Marie Vonach, Alain Gast, Andreas Kuglstatter, Markus G. Rudolph, Przemyslaw Nogly, Joerg Benz, Roger J.P. Dawson, Joerg StandfussSummaryThe CC chemokine receptor 7 (CCR7) balances immunity and tolerance by homeostatic trafficking of immune...
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Publication date: 22 August 2019Source: Cell, Volume 178, Issue 5Author(s): Roberta Buono, Valter D. LongoCycles of fasting reduce autoimmunity and activate lymphocyte-dependent killing of cancer cells, but the mechanisms remain poorly understood. Three studies in this issue of Cell begin to reveal the drastic and complex effects of fasting and severe calorie restriction on the levels and localization of different immune cells and the mechanisms responsible for them. (Source: Cell)
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Publication date: Available online 23 August 2019Source: CytotherapyAuthor(s): SOO JI kim, GIRAK KIM, NARAE KIM, HYUK CHU, BYUNG-CHUL PARK, JAE SEUNG YANG, SEUNG HYUN HAN, CHEOL-HEUI YUNAbstractHuman CD141+ dendritic cells (DCs), specialized for cross-presentation, have been extensively studied in the development of DC-based therapy against cancer. A series of attempts was made to generate CD141+ DCs from cord blood CD34+ hematopoietic progenitors to overcome the practical limitation of in vivo rareness....
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Publication date: Available online 22 August 2019Source: Journal of Clinical NeuroscienceAuthor(s): Shih-Ying Chen, Jun-Jun Lee, Chun-Chih Chien, Wan-Chen Tsai, Cheng-Hsien Lu, Wen-Neng Chang, Chia-Yi LienAbstractThe clinical characteristics and therapeutic outcomes of adult Listeria monocytogenes meningitis are not commonly examined in isolation in the literature. During a study period of 19 years (2000–2018), 366 patients with culture-proven adult bacterial meningitis (ABM) were identified in the...
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ConclusionsEven when whole tumor uptakes in patients with T3/T4 tumors markedly decreases after induction chemoradiotherapy, surgical treatment is still be indicated because of possible residual tumors. Tumor remission at extrapulmonary involvement sites could be predicted by extrapulmonary uptake values. Both whole- and extrapulmonary uptake values after induction chemoradiotherapy could be used to predict prognosis. (Source: The Annals of Thoracic Surgery)MedWorm Message: If you are looking to...
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ConclusionsOpioid dependence in the over 65-year old population after lung resection is high but was significantly lower among those who received minimally invasive surgery, in addition to other factors. (Source: The Annals of Thoracic Surgery)
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Publication date: Available online 22 August 2019Source: Journal of Food Composition and AnalysisAuthor(s): Sherif M. Elgammal, Mona A. Khorshed, Eman H. IsmailAbstractWhey protein is a by-product obtained from cheese manufacturing, contains high amounts of essential metals and amino acids. We assessed levels and health risk of Co, Ni, Sn, Cr, Cu, Mn, Zn, Fe, Al, Na, Ca, Mg, Pb, Cd, and Hg in different whey protein samples collected in Egypt using inductively coupled plasma optical emission spectrometry...
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CONCLUSION: This first randomized resistance training trial in pancreatic cancer patients indicated clinically relevant improve- ments in QoL after 3 but not after 6 months. Given the severity of pancreatic cancer, exercise recommendations may already commence at surgery. PMID: 31431236 [PubMed - in process] (Source: Deutsches Arzteblatt International)MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
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Authors: Ahlawat S, Singh D, Virdi JS, Sharma KK Abstract Synthetic dyes are toxic and carcinogenic in nature, which also causes environmental pollution. The present study was aimed to decolorize various commercial dyes using purified recombinant bacterial laccases. Laccase gene from Yersinia enterocolitica strain 8081 (yacK), Y. enterocolitica strain 7 (yacK) and Bacillus pumilus DSKK1 was cloned in vector pET28a and overproduced in host Escherichia coli BL21. The high yield of recombinant...
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In conclusion, the PRPF4 gene plays an important role in the growth of breast cancer cells and is therefore a potential therapeutic target. (Source: Molecular and Cellular Probes)MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm running.
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Publication date: 15 December 2019Source: Journal of Molecular Structure, Volume 1198Author(s): Lei Wang, Gui-Bin XueAbstractSolvothermal reactions of 1, 3, 5-tris (4-carboxyphenyl)-benzene (H3BTB) with Gd(NO3)·6H2O gave rise to a new highly porous coordination polymer {[Gd(BTB)(H2O)](DMF)(H2O)}n (1) having three dimensional structure. In light of its highly rigid framework as well as the large one-dimensional triangular channel configuration that has abundant open metal sites, we can utilize the...
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Publication date: 15 December 2019Source: Journal of Molecular Structure, Volume 1198Author(s): Liji John, Arish Dasan, R. Selwin Joseyphus, I. Hubert JoeAbstractCo(II), Ni(II), Cu(II) and Zn(II) complexes of Schiff base ligand (thio-L-his) derived from thiophene-2-carboxaldehyde (thio) with l-histidine (L-his) were synthesised. The thio-L-his and its metal complexes have been optimized and quantum chemical parameters are calculated using density functional theory. Despite several donor sites in...
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Publication date: Available online 20 August 2019Source: Journal of Molecular LiquidsAuthor(s): Sadegh Farhadian, Behzad Shareghi, Farhang Tirgir, Somayeh Reiisi, Neda Gholamian Dehkordi, Lida Momeni, Ehsan HeidariAbstractOver the past decades, anti-cancer drugs consist of cytotoxic drugs have been interested and developed. Despite the great advances in chemotherapy, there is still no certain medical treatment for cancer. During this investigation, a novel 2,5-diketopiperazine derivative 3(R),6(S)-bis...
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In this study, we performed RNA-sequencing analysis of MCF10A cells and identified 1166 genes that were upregulated and 861 genes that were downregulated by TGF-β. Gene set enrichment analysis revealed that focal adhesion and metabolic pathways were the top enriched pathways of the up- and downregulated genes, respectively. Genes in these pathways also possess significant predictive value for renal cancers. Moreover, we confirmed that TGF-β induced expression of MICAL1 and 2, and the histone demethylase,...
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Publication date: Available online 22 August 2019Source: Life SciencesAuthor(s): Yang Ge, Bao-lin Liu, Jun-peng Cui, Shu-qiang LiAbstractLivin is an important member of the human inhibitor of apoptosis proteins (IAPs) family. IAPs are proteins with antiapoptotic abilities, and their functions are different from the Bcl-2 (B-cell lymphoma-2) family proteins. However, the precise role of Livin in colon cancer progression remains unclear. The purpose of this study is to assess the effect of overexpression...
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Publication date: Available online 20 August 2019Source: Carbohydrate PolymersAuthor(s): Xin Xie, Lingman Ma, Yiran Zhou, Wen Shen, Duiyue Xu, Jie Dou, Baiyong Shen, Changlin ZhouAbstractA polysaccharide isolated from Strongylocentrotus nudus eggs (SEP) reportedly displays immune activity in vivo. Here, its effect and underlying mechanism in the treatment of pancreatic cancer were investigated. SEP obviously inhibited pancreatic cancer growth by activating NK cells in vitro/vivo via TLR4/MAPKs/NF-κB...
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Publication date: 1 December 2019Source: Carbohydrate Polymers, Volume 225Author(s): Ecaterina Stela Dragan, Maria Valentina DinuAbstractMacromolecular drugs, such as proteins and peptides, are lately readily available and used in the treatment of diseases including diabetes and cancer, as well as in therapies such as gene therapy, wound dressing, and tissue engineering. However, the bioavailability, the extent and the rate at which these drugs reach the target tissue are highly dependent on the...
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Publication date: Available online 15 August 2019Source: Carbohydrate PolymersAuthor(s): Yaping Wang, Junmin Qian, Ming Yang, Weijun Xu, Jinlei Wang, Guanghui Hou, Lijie Ji, Aili SuoAbstractCombination chemotherapy has attracted more and more attention in the field of anticancer treatment. Herein, a synergetic targeted combination chemotherapy of doxorubicin (DOX) and cisplatin in breast cancer was realized by HER2 antibody-decorated nanoparticles assembled from aldehyde hyaluronic acid (AHA) and...
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