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Τετάρτη 21 Αυγούστου 2019

Enhanced recovery after head and neck cancer reconstruction with a free flap – what is next?
Publication date: Available online 20 August 2019Source: Journal of Oral and Maxillofacial SurgeryAuthor(s): Jens H. Højvig, Henrik Kehlet, Christian T. Bonde
Oral and Maxillofacial Surgery
18h
The Growth Mindset. A contextualization of faculty development
Publication date: Available online 20 August 2019Source: Journal of Oral and Maxillofacial SurgeryAuthor(s): Eric R. Carlson, R. John Tannyhill
Oral and Maxillofacial Surgery
18h
Stereotactic ablative radiotherapy for pulmonary recurrence-based oligometastatic non-small cell lung cancer: survival and prognostic value of regulatory T cells
Publication date: Available online 19 August 2019Source: International Journal of Radiation Oncology*Biology*PhysicsAuthor(s): Chao Liu, Bing Sun, Xiaoyu Hu, Yun Zhang, Qian Wang, Jinbo Yue, Jinming YuAbstractPurposeWe evaluated survival of patients with pulmonary recurrence-based oligometastatic non-small cell lung cancer (NSCLC) whose lesions were all treated with stereotactic ablative radiotherapy (SABR) and the prognostic value of peripheral immune cells.Methods and MaterialsIn this prospective...
Radiation Molecular Biology.
18h
Defining the Dorsal STN Border Using 7.0-T MRI: A Comparison to Microelectrode Recordings and Lower Field Strength MRI
Background: 7.0-T T2-weighted MRI offers excellent visibility of the subthalamic nucleus (STN), which is used as a target for deep brain stimulation (DBS) in Parkinson’s disease (PD). A comparison of 7.0-T MRI to microelectrode recordings (MER) for STN border identification has not been performed. Objective: To compare representation of STN borders on 7.0-T T2 MRI with the borders identified during MER in patients undergoing DBS for PD and to evaluate whether STN identification on 7.0-T T2 MRI leads...
American Society for Stereotactic and Functional Neurosurgery
18h
DNA damage enhancement by radiotherapy-activated hafnium oxide nanoparticles improves cGAS-STING pathway activation in human colorectal cancer cells
Publication date: Available online 19 August 2019Source: Radiotherapy and OncologyAuthor(s): Julie Marill, Naeemunnisa Mohamed Anesary, Sébastien ParisAbstractThe cGAS-STING pathway can be activated by radiation induced DNA damage and because of its important role in anti-cancer immunity activation, methods to increase its activation in cancer cells could provide significant therapeutic benefits for patients. We explored the impact of hafnium oxide nanoparticles (NBTXR3) activated by radiotherapy...
Radiotherapy and Oncology
19h
<sup>18</sup>F-FDG-PET/CT-based treatment planning for definitive (chemo)radiotherapy in patients with head and neck squamous cell carcinoma improves regional control and survival
Publication date: Available online 19 August 2019Source: Radiotherapy and OncologyAuthor(s): Sven van den Bosch, Patricia A.H. Doornaert, Tim Dijkema, Ellen M. Zwijnenburg, Lia C.G. Verhoef, Bianca A.W. Hoeben, Nicolien Kasperts, Ernst J. Smid, Chris H.J. Terhaard, Johannes H.A.M. KaandersAbstractBackground and purposeMultimodality imaging including 18F-FDG-PET has improved the detection threshold of nodal metastases in head and neck squamous cell carcinoma (HNSCC). The aim of this retrospective...
Radiotherapy and Oncology
19h
Chemoradiotherapy of locally-advanced non-small cell lung cancer: Analysis of radiation dose–response, chemotherapy and survival-limiting toxicity effects indicates a low α/β ratio
Publication date: Available online 19 August 2019Source: Radiotherapy and OncologyAuthor(s): Michael G. Nix, Carl G. Rowbottom, Sindu Vivekanandan, Maria A. Hawkins, John D. FenwickAbstractPurposeTo analyse changes in 2-year overall survival (OS2yr) with radiotherapy (RT) dose, dose-per-fraction, treatment duration and chemotherapy use, in data compiled from prospective trials of RT and chemo-RT (CRT) for locally-advanced non-small cell lung cancer (LA-NSCLC).Material and methodsOS2yr data was analysed...
Radiotherapy and Oncology
19h
Dosimetric parameters predictive of nasolacrimal duct obstruction after carbon-ion radiotherapy for head and neck carcinoma
Publication date: Available online 19 August 2019Source: Radiotherapy and OncologyAuthor(s): Nobuteru Kubo, Yoshiki Kubota, Hidemasa Kawamura, Takahiro Oike, Makoto Sakai, Takuya Kumazawa, Yuhei Miyasaka, Shohei Okazaki, Daijiro Kobayashi, Hiro Sato, Tatsuji Mizukami, Atsushi Musha, Katsuyuki Shirai, Jun-ichi Saitoh, Satoshi Yokoo, Kazuaki Chikamatsu, Tatsuya Ohno, Takashi NakanoAbstractBackground and purposeLittle information is available on the risk factors for nasolacrimal duct obstruction after...
Radiotherapy and Oncology
19h
An adenosine derivative (IFC-305) reduced the risk of radiation-induced intestinal toxicity in the treatment of colon cancer by suppressing the methylation of PPAR-r promoter
Publication date: October 2019Source: Biomedicine & Pharmacotherapy, Volume 118Author(s): Bo Lian, Yupeng Ren, Hao Zhang, Tao Lin, Yongpeng WangAbstractBackgroundIFC-305, an adenosine derivative, has been proved to exert a therapeutic effect on radiation-induced intestinal toxicity in colon cancer (CC). The aim of the present study was to investigate the underlying molecular mechanism of protective role of IFC-305 in CC by modifying the methylation of peroxisome proliferator-activated receptor...
Biomedicine & Pharmacotherapy
19h
Absorption and utilisation of epimedin C and icariin from <em>Epimedii</em> herba, and the regulatory mechanism via the BMP2/ Runx2 signalling pathway
Publication date: October 2019Source: Biomedicine & Pharmacotherapy, Volume 118Author(s): Xiaowen Huang, Xuping Wang, Yang Zhang, Lifeng Shen, Nani Wang, Xuefeng Xiong, Li Zhang, Xiaobin Cai, Dan ShouAbstractBone nonunion remains a challenge during the treatment of bone defect accompanied with infection. Epimedii herba is a widely used medicine in clinic to enhance bone healing. Epimedin C and icariin are the major flavonoid glycosides from Epimedii herba. Although the effects of these compounds...
Biomedicine & Pharmacotherapy
19h
FAM83H-AS1 is upregulated and predicts poor prognosis in colon cancer
Publication date: October 2019Source: Biomedicine & Pharmacotherapy, Volume 118Author(s): Lei Yang, Jinpeng Cui, Yakun Wang, Jinjing TanAbstractLong noncoding RNAs (LncRNAs) have been proven to participate in many principal pathways during colonic mucosa tumourigenesis. FAM83H-AS1 has been identified as one of the LncRNAs that is dysregulated in multi-type cancers. Here, our purpose was to determine the expression pattern and clinical significance of FAM83H-AS1 and further analyse its prognostic...
Biomedicine & Pharmacotherapy
19h
The lncRNA EGFR-AS1 is linked to migration, invasion and apoptosis in glioma cells by targeting miR-133b/RACK1
Publication date: October 2019Source: Biomedicine & Pharmacotherapy, Volume 118Author(s): Zhi-Qiang Dong, Zhao-Yu Guo, Jun XieAbstractGlioblastoma multiforme (GBM) is the most common in situ neoplasms in central nervous system (CNS). However, the pathogenesis of GBM is poorly understood. Long noncoding RNAs (lncRNAs) have been implicated in GBM progression. In this study, we attempted to identify the biological role of the EGFR-AS1 in glioma cells and tissues, as well as reveal the molecular...
Biomedicine & Pharmacotherapy
19h
Quantitative and qualitative features of executive dysfunction in frontotemporal and Alzheimer's dementia.
Related ArticlesQuantitative and qualitative features of executive dysfunction in frontotemporal and Alzheimer's dementia. Appl Neuropsychol Adult. 2019 Aug 19;:1-15 Authors: Kiselica AM, Benge JF Abstract Behavioral variant fronto-temporal degeneration (bvFTD) is typically distinguished from Alzheimer's disease (AD) by early, prominent dysexecutive findings, in addition to other clinical features. However, differences in executive functioning between...
pubmed: misdiagnosis of alzh...
19h
Utilizing semantic intrusions to identify amyloid positivity in mild cognitive impairment.
Related ArticlesUtilizing semantic intrusions to identify amyloid positivity in mild cognitive impairment. Neurology. 2018 09 04;91(10):e976-e984 Authors: Loewenstein DA, Curiel RE, DeKosky S, Bauer RM, Rosselli M, Guinjoan SM, Adjouadi M, Peñate A, Barker WW, Goenaga S, Golde T, Greig-Custo MT, Hanson KS, Li C, Lizarraga G, Marsiske M, Duara R Abstract OBJECTIVE: Semantic intrusion (SI) errors may highlight specific breakdowns in memory associated...
pubmed: misdiagnosis of alzh...
19h
The Potential Role of Seminal Plasma in the Fertilization Outcomes
For human infertility both male and female factors may be equally important. Searching for molecular biomarkers of male infertility, neglected for decades, and the attempts to explain regulatory mechanisms of fertilization become thus extremely important. Apart from examination of the structure and function of male gametes, also the possible importance of seminal plasma components should be considered. In this article we discuss data that indicate for the substantial significance of active seminal...
BioMed Research International
19h
Pro-Con Debate: Nitrous Oxide for Labor Analgesia
This Pro-Con debate will provide the practitioner with an evidence-based knowledge approach to assist the clinician in determining whether to employ (Pro) or not to employ (Con) this technique in the obstetrical suite for labor analgesia. Nitrous oxide has been used safely in dentistry and medicine for many centuries. However, accumulating preclinical and clinical evidence increasingly suggests previously unrecognized adverse maternal and fetal effects of nitrous oxide, which warrants reconsideration...
BioMed Research International
19h
An Economic Analysis of the Systematic Use of Mapping Systems during Catheter Ablation Procedures: Single Center Experience
Introduction. In this study we estimated the cost-effectiveness of adopting 3D Nonfluoroscopic Mapping Systems (NMSs) for catheter ablation (CA). Methods. This study includes patients who underwent supraventricular tachycardia (SVT) CA and atrial fibrillation (AF) CA from 2007 to 2016. A comparison was conducted between a reference year (2007) and the respective years for the two types of procedure in which the maximum optimization of patients’ exposure using NMSs was obtained. We compared the data...
BioMed Research International
19h
A 6-Gene Risk Signature Predicts Survival of Glioblastoma Multiforme
Background. This study aims to develop novel signatures for glioblastoma multiforme (GBM). Methods. GBM expression profiles from The Cancer Genome Atlas (TCGA) were downloaded and DEGs between tumor and normal samples were identified by differential expression analysis (DEA). A risk signature was developed by applying weighted gene coexpression network analysis (WGCNA) and Cox regression analysis. Patients were divided into high and low risk group, followed by evaluating the performance of the signature...
BioMed Research International
19h
Quercetin Inhibits Inflammatory Response Induced by LPS from Porphyromonas gingivalis in Human Gingival Fibroblasts via Suppressing NF-κB Signaling Pathway
Quercetin, a natural flavonol existing in many food resources, has been reported to be an effective antimicrobial and anti-inflammatory agent for restricting the inflammation in periodontitis. In this study, we aimed to investigate the anti-inflammatory effects of quercetin on Porphyromonas gingivalis (P. gingivalis) lipopolysaccharide- (LPS-) stimulated human gingival fibroblasts (HGFs). HGFs were pretreated with quercetin prior to LPS stimulation. Cell viability was evaluated by 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium...
BioMed Research International
20h
The Diagnostic Performance of Afirma Gene Expression Classifier for the Indeterminate Thyroid Nodules: A Meta-Analysis
Background. Approximately 15 to 30% of thyroid nodules evaluated by fine-needle aspiration (FNA) were classified as indeterminate; the accurate diagnostic molecular tests of these nodules remain a challenge. We aimed to evaluate the diagnostic performance of Afirma gene expression classifier (GEC) for the indeterminate thyroid nodules (ITNs). Methods. Studies published from January 2005 to December 2018 were systematically reviewed. The gold reference standard relied on the histopathologic results...
BioMed Research International
23h
High Public-Health Impact in an Influenza-B-Mismatch Season in Southern Italy, 2017-2018
Background. Yearly influenza epidemics have considerable effects on public health worldwide. The 2017-2018 influenza season in Italy was of greater severity than previous seasons. The aim of this study was to describe the 2017-2018 influenza season in Southern Italy and the molecular characteristics of the circulating viral strains. Methods. The incidence of influenza-like illness (ILI) was analysed. Nasopharyngeal swabs collected from patients with ILI from week 46/2017 to week 17/2018 were tested...
BioMed Research International
1d
A Comparison between Primary and Secondary Flap Coverage in Ridge Preservation Procedures: A Pilot Randomized Controlled Clinical Trial
Aims. To assess the bone dimensional changes after extraction and alveolar ridge preservation (ARP) using primary coverage (closed flap technique, CFT) or healing by secondary intention (open flap technique, OFT). Materials and Methods. Ten patients (split mouth design) were planned for extraction and ARP. All sites received ARP with freeze-dried bone allograft (FDBA) and nonresorbable membrane after extraction. Clinical standardized measurements were used to assess the dimensional alterations of...
BioMed Research International
1d
Optimization and Identification of Antioxidant Peptide from Underutilized Dunaliella salina Protein: Extraction, In Vitro Gastrointestinal Digestion, and Fractionation
DPPH• scavenging peptides (
BioMed Research International
1d
An Overview of Tuberculosis-Designated Hospitals in China, 2009-2015: A Longitudinal Analysis of National Survey Data
Design. A national tuberculosis- (TB-) designated hospital survey was conducted in 2015 to identify significant changes since 2009 in implementation of TB-testing services within hospitals of various types and administrative levels in various regions in China. Methods. In 2015, all TB-designated hospitals were required to complete questionnaires designed by the National Clinical Center for TB. Community hospitals also completed simplified questionnaires as part of the study. Results. Overall, in...
BioMed Research International
1d
Prevalence of potential candidates for electric-acoustic stimulation implant in a hearing-impaired population
Publication date: Available online 20 August 2019Source: Auris Nasus LarynxAuthor(s): Kazuya Saito, Takeshi Fujita, Yasuhiro Osaki, Hajime Koyama, Ko Shiraishi, Takaaki Kobayashi, Mitsuo Sato, Toru Seo, Katsumi DoiAbstractObjectiveTo estimate the prevalence of potential electric-acoustic stimulation (EAS) implant candidates in a hearing-impaired population through a review of auditory examinations.MethodsIn total, 7356 patients underwent audiometric examination in our department between 2011 and...
Auris Nasus Larynx
19h
The cheek expander enables tonsillectomy with a wide view and working space
Publication date: Available online 20 August 2019Source: Auris Nasus LarynxAuthor(s): Takashi Anzai, Atsunobu Tsunoda, Shori Tajima, Shin Ito, Katsuhisa IkedaAbstractObjectiveTonsillectomy is the most commonly performed otolaryngological surgeries.Although a surgical method had been established, obtaining a clear surgical field still remains problematic, and injury to the corners of the mouth may occur. For safer tonsillectomy, we use a cheek expander coupled with a Davis mouth gag. The devise retract...
Auris Nasus Larynx
19h
Immunoinflammatory responses to febrile lower respiratory infections in infants display uniquely complex/intense transcriptomic profiles
Publication date: Available online 19 August 2019Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Anya C. Jones, Denise Anderson, Sally Galbraith, Emmanuelle Fantino, Diana Gutierrez Cardenas, James F. Read, Michael Serralha, Barbara J. Holt, Deborah H. Strickland, Peter D. Sly, Anthony Bosco, Patrick G. Holt
Allergy and Clinical Immunology
19h
Prenatal Oxidative Balance and Risk of Asthma and Allergic Disease in Adolescence
Publication date: Available online 19 August 2019Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Joanne E. Sordillo, Sheryl L. Rifas-Shiman, Karen Switkowski, Brent Coull, Heike Gibson, Mary Rice, Thomas Platts-Mills, Itai Kloog, Augusto A. Litonjua, Diane R. Gold, Emily OkenAbstractBackgroundFetal oxidative balance (achieved when protective prenatal factors counteract sources of oxidative stress), may be critical for preventing asthma and allergic disease.ObjectiveWe examined prenatal...
Allergy and Clinical Immunology
19h
CD23 provides a non-inflammatory pathway for IgE-allergen complexes
Publication date: Available online 19 August 2019Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Paul Engeroff, Flurin Caviezel, David Mueller, Franziska Thoms, Martin F. Bachmann, Monique VogelAbstractBackgroundType I hypersensitivity is mediated by allergen-specific IgE which sensitizes the high-affinity IgE receptor FcεRI on mast cells and basophils which drive allergic inflammation upon secondary allergen contact. CD23/FcεRII, the low affinity receptor for IgE is constitutively expressed...
Allergy and Clinical Immunology
19h
Immune checkpoint inhibitors: a new era for esophageal cancer.
Related ArticlesImmune checkpoint inhibitors: a new era for esophageal cancer. Expert Rev Anticancer Ther. 2019 Aug 19;:1-8 Authors: Zou LQ, Yang X, Li YD, Zhu ZF Abstract Introduction: The poor prognosis for patients with esophageal cancer (EC) requires evolving current treatment regimens. Immune checkpoint inhibitors show clinical efficacy and a great safety profile in multiple tumors. And the monoclonal antibodies that target programmed death receptor-1/programmed...
pubmed: expert review of ant...
19h
Hedgehog pathway inhibition as a therapeutic target in acute myeloid leukemia.
Related ArticlesHedgehog pathway inhibition as a therapeutic target in acute myeloid leukemia. Expert Rev Anticancer Ther. 2019 Aug 17;:1-13 Authors: Shallis RM, Bewersdorf JP, Boddu PC, Zeidan AM Abstract Introduction: The Hedgehog (HH) pathway constitutes a collection of signaling molecules which critically influence embryogenesis. In adults, however, the HH pathway remains integral to the proliferation, maintenance, and apoptosis of adult stem cells...
pubmed: expert review of ant...
19h
Pathophysiologie der obstruktiven Schlafapnoe
Zusammenfassung Die Prävalenz der obstruktiven Schlafapnoe (OSA) wird in den westlichen Industrieländern als sehr hoch angenommen. Für die Behandlung des OSA gibt es konservative und operative Therapien. Die Pathophysiologie ist dennoch weitestgehend ungeklärt und lässt sich nicht allein durch anatomische Auffälligkeiten erklären. So konnte in den letzten Jahren eine Reihe nichtanatomischer Faktoren identifiziert werden, die die Entstehung einer OSA begünstigen. Hierunter fallen...
HNO
20h
Angiotensin-(1-7) oral treatment after experimental myocardial infarction leads to downregulation of CXCR4
Publication date: Available online 19 August 2019Source: Journal of ProteomicsAuthor(s): Diana Paola Gómez-Mendoza, Fúlvia Dias Marques, Marcella Nunes Melo-Bragaa, Richard R. Sprenger, Rubén Dario Sinisterra, Frank Kjeldsen, Robson Augusto Santos, Thiago Verano-BragaAbstractMyocardial infarction triggers cellular events that starts with the activation of inflammatory response and fibrogenic pathways involved in cardiac tissue remodeling. Angiotensin-(1–7) (Ang-(1–7)) is an endogenous heptapeptide...
ScienceDirect Publication: Journal of Proteomics
20h
Recovery of <em>Curvularia</em> mold from a duodenoscope after reprocessing in accordance with the manufacturer's cleaning protocol
Publication date: Available online 20 August 2019Source: American Journal of Infection ControlAuthor(s): Deena Schuman, Scott Brown, Susan M. Mistretta, John Delano, Nicole M. IovineIn 2018, the Food and Drug Administration/Centers for Disease Control and Prevention revised protocols for surveillance sampling and cultures of duodenoscopes. We describe the recovery of the mold Curvularia from a duodenoscope processed according to the manufacturer's instructions using this revised sampling process....
ScienceDirect Publication: American Journal of Infection Control
20h
Does systemic antibiotic prophylaxis prior to the placement of totally implantable venous access devices reduce early infection? A retrospective study of 1,485 cases at a large academic institution
Publication date: Available online 20 August 2019Source: American Journal of Infection ControlAuthor(s): Ankur Choksi, Karen Finnegan, Vahid EtezadiBackgroundTo determine if ending the practice of administering prophylactic antibiotics prior to the placement of totally implantable venous access devices (TIVADs) is correlated with an increase in 30-day bloodstream infection–related TIVADs removals.MethodsThe practice of administering prophylactic antibiotics prior to the placement of TIVADs ended...
ScienceDirect Publication: American Journal of Infection Control
20h
[POLO study].
Related Articles[POLO study]. Bull Cancer. 2019 Aug 13;: Authors: Hammel P PMID: 31420091 [PubMed - as supplied by publisher]
Association française pour l'étude du cancer
20h
Future Oncology; +56 new citations
56 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2019/08/20PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
pubmed: future oncology
20h
Future Oncology; +56 new citations
56 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2019/08/20PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
pubmed: future oncology
22h

The protective effect of Stevia rebaudiana Bertoni on serum hormone levels, key steroidogenesis enzymes, and testicular damage in testes of diabetic rats.
Related ArticlesThe protective effect of Stevia rebaudiana Bertoni on serum hormone levels, key steroidogenesis enzymes, and testicular damage in testes of diabetic rats. Acta Histochem. 2019 Aug 13;: Authors: Gholizadeh F, Dastghaib S, Koohpeyma F, Bayat E, Mokarram P Abstract Diabetes Mellitus (DM) is a kind of metabolic endocrine diseases, which has various effects on the gonadal system. The current study aimed to examine the effect of Stevia rebaudiana...
histochem
20h
« Définition des volumes cibles : quand et comment l’oncologue radiothérapeute peut-il utiliser la TEP ? »
Publication date: Available online 19 August 2019Source: Cancer/RadiothérapieAuthor(s): S. Thureau, E. Texte, P. Decazes, D. Gensanne, P. Gouel, R. Modzelewski, S. Hapdey, P. VeraRésuméLa TEP/tomodensitométrie est devenue un examen standard en cancérologie mais reste probablement sous-utilisée pour la planification de la radiothérapie. Pourtant en dehors des données de recherche clinique qui montre l’intérêt de cet examen pour envisager une radiothérapie personnalisée et adaptative, elle est également...
Cancer/Radiothérapie
20h
ALCOHOL; +184 new citations
184 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: ALCOHOL These pubmed results were generated on 2019/08/20PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Alcohol
20h
ALCOHOL; +184 new citations
184 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: ALCOHOL These pubmed results were generated on 2019/08/20PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Alcohol
22h
Comparison of Early and Late Post-operative Outcomes after Supra-inguinal Bypass for Aortoiliac Occlusive Disease
Publication date: Available online 19 August 2019Source: European Journal of Vascular and Endovascular SurgeryAuthor(s): Zein M. Saadeddin, Denis V. Rybin, Gheorghe Doros, Jefferey J. Siracuse, Alik Farber, Mohammad H. EslamiObjectiveThe choice for surgical revascularisation for aortoiliac occlusive disease is often tempered by patient comorbidities. This study compares peri-operative outcomes and the association between choice of operation and one year major adverse limb event (MALE) free survival...
ScienceDirect Publication: European Journal of Vascular and Endovascular Surgery
20h
Encorafenib and Binimetinib With or Without Nivolumab in Treating Patients With Metastatic Radioiodine Refractory BRAF V600 Mutant Thyroid Cancer
Conditions:   BRAF NP_004324.2:p.V600M;   BRAF V600E Mutation Present;   Metastatic Thyroid Gland Carcinoma;   Refractory Thyroid Gland Carcinoma;   Stage IV Differentiated Thyroid Gland Carcinoma AJCC v8;   Stage IVA Differentiated Thyroid Gland Carcinoma AJCC v8;   Stage IVB Differentiated Thyroid Gland Carcinoma AJCC v8Interventions:   Drug: Binimetinib;   Drug: Encorafenib;   Biological: NivolumabSponsors:   OHSU Knight Cancer Institute;   National Cancer Institute (NCI)Not yet recruiting
ClinicalTrials
21h
Perioperative Chemotherapy vs Immunotherapy vs. Chemo-immunotherapy in Patients With Advanced GC and AEG
Conditions:   Gastric Cancer;   Adenocarcinoma of the Esophagogastric JunctionInterventions:   Drug: Nivolumab;   Drug: Ipilimumab;   Drug: Relatlimab;   Drug: Oxaliplatin;   Drug: Docetaxel;   Drug: 5-Fluorouracil;   Drug: Folic acidSponsors:   Jan Ellermeier;   GWT-TUD GmbHNot yet recruiting
ClinicalTrials
21h
Inhibitory effect of <em>Acer tegmentosum</em> maxim extracts on <em>P. gingivalis</em> LPS-induced periodontitis
Publication date: Available online 19 August 2019Source: Archives of Oral BiologyAuthor(s): Go-Eun Choi, Kyung-Yae HyunAbstractObjectivePeriodontitis disease is a chronic inflammation, and the prevention or treatment of periodontal disease is important for improving oral health and averting systemic diseases.Acer tegmentosum Maxim (ATM) is a type of deciduous tree in Korea. ATM extracts have been traditionally used to treat various dieases. This study investigated the effects of ATM extract on mitigation...
Oral Biology
21h
Lymphoid Neoplasms of the Oral Cavity with Plasmablastic Morphology – A Case Series and Review of the Literature
Publication date: Available online 19 August 2019Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologyAuthor(s): S. Bhattacharyya, A. Bains, D.L. Sykes, B.R. Iverson, R. Sibgatullah, R.M. KuklaniAbstractPlasmablastic Lymphoma (PBL) is a rare aggressive variant of large B-cell lymphoma defined as a proliferation of large neoplastic plasmablasts/immunoblasts. PBL was first described as a distinct entity in a group of 16 patients with lymphoma of the oral cavity. The majority of patients...
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
21h
Tumor Depth of Invasion versus Tumor Thickness in Guiding Regional Nodal Treatment in Early Oral Tongue Squamous Cell Carcinoma
Publication date: Available online 19 August 2019Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologyAuthor(s): Brendan Liu, Rajith Amaratunga, Michael Veness, Eva Wong, Muzib Abdul Razak, Hedley Coleman, Val Gebski, Puma SundaresanAbstractObjectivesTumor thickness (TT) and tumor depth of invasion (DOI) correlate with the risk of regional lymph node metastases in early oral tongue squamous cell carcinoma (OTSCC). We aimed to determine optimal cut-points to guide elective nodal treatment...
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
21h
human physiology; +198 new citations
198 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human physiology These pubmed results were generated on 2019/08/20PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Human physiology
21h
human physiology; +198 new citations
198 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human physiology These pubmed results were generated on 2019/08/20PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Human physiology
23h
Probabilistic neuroanatomical assignment of intracranial electrodes using the ELAS toolbox
Publication date: Available online 19 August 2019Source: Journal of Neuroscience MethodsAuthor(s): Joos Behncke, Markus Kern, Johanna Ruescher, Andreas Schulze-Bonhage, Tonio BallAbstractBackgroundIntracranial electroencephalography (iEEG) is increasingly used in neuroscientific research. However, the position of the implanted electrodes varies greatly between patients, which makes group analyses particularly difficult. Therefore, an assignment procedure is needed that enables the neuroanatomical...
Journal of Neuroscience Methods
21h
High-frequency oscillations in a spectrum of pediatric epilepsies characterized by sleep-activated spikes in scalp EEG
Publication date: Available online 19 August 2019Source: Clinical NeurophysiologyAuthor(s): Yuji Ohuchi, Tomoyuki Akiyama, Masao Matsuhashi, Katsuhiro KobayashiAbstractObjectiveWe studied ripple-band (80–200 Hz) high-frequency oscillations in scalp electroencephalogram (EEG) in various pediatric epilepsies featuring sleep-activated spikes, such as epileptic encephalopathy with continuous spike-and-wave during sleep (CSWS) and investigated their characteristics.MethodsThe subjects were 94 children...
Clinical Neurophysiology
21h
Best abstract award. Development of CTS SCORE for rapid assessment of carpal tunnel syndrome diagnosis and severity
Publication date: Available online 6 August 2019Source: Clinical NeurophysiologyAuthor(s): Mark Anthony Sta. Maria, Jose Paciano Reyes
Clinical Neurophysiology
21h
upper respiratory tract infection; +64 new citations
64 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: upper respiratory tract infection These pubmed results were generated on 2019/08/20PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Upper respiratory tract infection
21h
upper respiratory tract infection; +64 new citations
64 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: upper respiratory tract infection These pubmed results were generated on 2019/08/20PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Upper respiratory tract infection
23h
Harvesting the ‘SEAD’: Long-Term Follow-Up of the Surgical Exploration and Discovery Program
Publication date: Available online 19 August 2019Source: Journal of Surgical EducationAuthor(s): Linden K. Head, Brittany Greene, Nada Gawad, Stanley J. Hamstra, Tim BrandysObjectiveThe Surgical Exploration and Discovery (SEAD) program was established to facilitate career decision-making by providing preclerkship students with comprehensive exposure to surgical specialties. Our short-term findings demonstrated that, compared to a control group, SEAD participants showed significantly greater career-related...
Journal of Surgical Education
21h
Cortical auditory evoked potentials in mild cognitive impairment: Evidence from a temporal-spatial principal component analysis.
Related ArticlesCortical auditory evoked potentials in mild cognitive impairment: Evidence from a temporal-spatial principal component analysis. Psychophysiology. 2019 Aug 17;:e13466 Authors: Buján A, Lister JJ, O'Brien JL, Edwards JD Abstract Mild cognitive impairment (MCI) is considered an intermediate transitional stage for the development of dementia, especially Alzheimer's disease. The identification of neurophysiological biomarkers for MCI will...
cortical auditory
21h
Large-Scale Cortical Networks for Hierarchical Prediction and Prediction Error in the Primate Brain.
Related ArticlesLarge-Scale Cortical Networks for Hierarchical Prediction and Prediction Error in the Primate Brain. Neuron. 2018 12 05;100(5):1252-1266.e3 Authors: Chao ZC, Takaura K, Wang L, Fujii N, Dehaene S Abstract According to predictive-coding theory, cortical areas continuously generate and update predictions of sensory inputs at different hierarchical levels and emit prediction errors when the predicted and actual inputs differ. However, predictions...
cortical auditory
21h
How might financial pressures have impacted brachytherapy? A proposed narrative to explain the declines in cervical and prostate brachytherapy utilization
Publication date: Available online 19 August 2019Source: BrachytherapyAuthor(s): Michael Schad, Roman Kowalchuk, Sushil Beriwal, Timothy N. ShowalterAbstractRates of brachytherapy administration in the United States have declined for both cervical and prostate cancers, and we argue that the available facts suggest financial considerations are a major contributor to this issue. In this narrative, we discuss financial pressures that have existed for cervical and prostate brachytherapy and how they...
Brachytherapy
21h
Treatment trends in oropharyngeal carcinoma: Surgical technology meets the epidemic.
Related ArticlesTreatment trends in oropharyngeal carcinoma: Surgical technology meets the epidemic. Oral Oncol. 2019 Aug 14;97:62-68 Authors: Gal TJ, Slezak JA, Kejner AE, Chen Q, Huang B Abstract OBJECTIVE: To characterize temporal trends in treatment patterns for oropharyngeal carcinoma, and to evaluate the emerging role of surgical therapy in the era of transoral robotic surgery (TORS). METHODS: Patients with oropharynx cancer between 2004...
Technologies in Treatment of Head & Neck
21h
[Effects of an Acupoint Intervention on Improving Fatigue and Heart Rate Variability in Head and Neck Cancer Patients Receiving Concurrent Chemoradiotherapy].
Related Articles[Effects of an Acupoint Intervention on Improving Fatigue and Heart Rate Variability in Head and Neck Cancer Patients Receiving Concurrent Chemoradiotherapy]. Hu Li Za Zhi. 2019 Jun;66(3):46-58 Authors: Chou YH, Wang YJ, Yeh ML, Lin CY Abstract BACKGROUND: Fatigue is the most common symptom in head and neck cancer patients who receive concurrent chemoradiotherapy (CCRT). However, evidence of the effects of acupoint interventions on fatigue...
Technologies in Treatment of Head & Neck
21h
The Anterior Ethmoidal "Genu": A Newly Appreciated Anatomic Landmark for Endoscopic Sinus Surgery.
Related ArticlesThe Anterior Ethmoidal "Genu": A Newly Appreciated Anatomic Landmark for Endoscopic Sinus Surgery. Clin Anat. 2019 May;32(4):534-540 Authors: Bolger WE, Stammberger H, Ishii M, Ponikau J, Solaiyappan M, Zinreich SJ Abstract Human sinonasal anatomy varies widely between patients, challenging surgeons operating in the sinuses. Ethmoid sinus anatomy is so variable it has been referred to as a labyrinth. Accordingly, reliable, consistent...
Technologies in Treatment of Head & Neck
21h
Anatomic Landmarks in Transoral Oropharyngeal Surgery.
Related ArticlesAnatomic Landmarks in Transoral Oropharyngeal Surgery. J Craniofac Surg. 2019 Mar/Apr;30(2):e101-e106 Authors: Mirapeix RM, Tobed Secall M, Pollán Guisasola C, Garcia Lorenzo J, Lluansí Planella J, Viña Soria C, Palau Viarnès M, Virós Porcuna D Abstract INTRODUCTION: Minimally invasive transoral surgery for oropharyngeal cancer is a challenge for head and neck surgeons because of the inside-out anatomic presentation and the confined...
Technologies in Treatment of Head & Neck
21h
Comparison the clinical outcomes with altered versus conventional fractionated radiotherapy plus concurrent chemotherapy for advanced nasopharyngeal carcinoma.
Related ArticlesComparison the clinical outcomes with altered versus conventional fractionated radiotherapy plus concurrent chemotherapy for advanced nasopharyngeal carcinoma. Head Neck. 2018 06;40(6):1156-1163 Authors: Lin PJ, Twu CW, Liu YC, Lin TY, Wang WY, Lin JC Abstract BACKGROUND: The purpose of this study was to compare the long-term survivals between altered fractionated and conventional fractionated radiotherapy with the same concurrent chemoradiotherapy...
Technologies in Treatment of Head & Neck
21h
Safety and efficacy of immunotherapy with the recombinant B-cell epitope-based grass pollen vaccine BM32.
Related ArticlesSafety and efficacy of immunotherapy with the recombinant B-cell epitope-based grass pollen vaccine BM32. J Allergy Clin Immunol. 2018 08;142(2):497-509.e9 Authors: Niederberger V, Neubauer A, Gevaert P, Zidarn M, Worm M, Aberer W, Malling HJ, Pfaar O, Klimek L, Pfützner W, Ring J, Darsow U, Novak N, Gerth van Wijk R, Eckl-Dorna J, Focke-Tejkl M, Weber M, Müller HH, Klinger J, Stolz F, Breit N, Henning R, Valenta R Abstract BACKGROUND:...
Technologies in Treatment of Head & Neck
21h
Parotid carcinoma and adjunct radiation therapy and the case for combined approach in paediatric antrochoanal surgery.
Related ArticlesParotid carcinoma and adjunct radiation therapy and the case for combined approach in paediatric antrochoanal surgery. J Laryngol Otol. 2019 Jul;133(7):545 Authors: Hussain M, Fishman J, Fisher E PMID: 31423960 [PubMed - in process]
The Journal of laryngology and otology http://goo.gl/Tl02xD
21h
Primary laryngeal lymphoma in China: a retrospective study of the last 25 years.
Related ArticlesPrimary laryngeal lymphoma in China: a retrospective study of the last 25 years. J Laryngol Otol. 2019 Aug 19;:1-4 Authors: Zhao P, Zhou Y, Li J Abstract OBJECTIVE: To retrospectively study the primary laryngeal lymphoma cases in China reported in Chinese-language literature. METHOD: Chinese-language literature was searched for papers on primary laryngeal lymphoma published in the last 25 years. RESULTS: The selected...
The Journal of laryngology and otology http://goo.gl/Tl02xD
21h
A study on modelling cochlear duct mid-scalar length based on high-resolution computed tomography, and its effect on peri-modiolar and mid-scalar implant selection.
Related ArticlesA study on modelling cochlear duct mid-scalar length based on high-resolution computed tomography, and its effect on peri-modiolar and mid-scalar implant selection. J Laryngol Otol. 2019 Aug 19;:1-6 Authors: Pamuk G, Pamuk AE, Akgöz A, Öztürk E, Bajin MD, Sennaroğlu L Abstract OBJECTIVE: To determine cochlear duct mid-scalar length in normal cochleae and its role in selecting the correct peri-modiolar and mid-scalar implant length. ...
The Journal of laryngology and otology http://goo.gl/Tl02xD
21h
Pain scores and recovery post tonsillectomy: intracapsular versus extracapsular coblation.
Related ArticlesPain scores and recovery post tonsillectomy: intracapsular versus extracapsular coblation. J Laryngol Otol. 2019 Aug 19;:1-7 Authors: Junaid M, Sood S, Walijee H, Dorgham J, De S Abstract OBJECTIVE: This study compared post-tonsillectomy pain scores and recovery using the coblation-only technique, comparing extracapsular versus intracapsular approaches. METHODS: A prospective study was performed in our paediatric ENT department....
The Journal of laryngology and otology http://goo.gl/Tl02xD
21h
Revisiting the sternocleidomastoid flap as a reconstructive option in head and neck surgery.
Related ArticlesRevisiting the sternocleidomastoid flap as a reconstructive option in head and neck surgery. J Laryngol Otol. 2019 Aug 19;:1-5 Authors: Jones LF, Farrar EM, Roberts DJH, Moor JW Abstract BACKGROUND: The sternocleidomastoid can be used as a pedicled flap in head and neck reconstruction. It has previously been associated with high complication rates, likely due in part to the variable nature of its blood supply. OBJECTIVE: To provide...
The Journal of laryngology and otology http://goo.gl/Tl02xD
21h
Management of epidural hematomas in pediatric patients presenting with a GCS of 14 or better.
Related ArticlesManagement of epidural hematomas in pediatric patients presenting with a GCS of 14 or better. J Clin Neurosci. 2019 Aug 14;: Authors: Bounajem MT, Samples DC, Wallace DJ, Tavakoli S, Liao L, Tarasiewicz I Abstract OBJECT: Guidelines for the management of pediatric epidural hematoma (PEDH) remain poorly defined. Here we seek to characterize the disease course of PEDH in patients with presenting Glasgow Coma Scale (GCS) of 14+, and suggest...
J Clin Neurosci
21h
Potential predictors of quality of life in Parkinson's Disease: Sleep and mood disorders.
Related ArticlesPotential predictors of quality of life in Parkinson's Disease: Sleep and mood disorders. J Clin Neurosci. 2019 Aug 14;: Authors: Palmeri R, Lo Buono V, Bonanno L, Sorbera C, Cimino V, Bramanti P, Di Lorenzo G, Marino S Abstract Sleep Disturbances are a non motor symptom very common in Parkinson's Disease characterized by insomnia, worse quality of sleep and Excessive Daytime Sleepiness. Several factors have been associated with these...
J Clin Neurosci
21h
Clinical observations on the release of tethered spinal cord in children with intra-operative neurophysiological monitoring: A retrospective study.
Related ArticlesClinical observations on the release of tethered spinal cord in children with intra-operative neurophysiological monitoring: A retrospective study. J Clin Neurosci. 2019 Aug 14;: Authors: Jiang J, Zhang S, Dai C, Jiang X, Niu X, Chen X, Tang F Abstract To study the utility of neurophysiological monitoring in the micro-surgical treatments on children with Tethered Cord Syndrome (TCS). A total of 100 patients were included in this study....
J Clin Neurosci
21h
Efficacy of combining home-based transcranial direct current stimulation with mindfulness-based meditation for pain in older adults with knee osteoarthritis: A randomized controlled pilot study.
Related ArticlesEfficacy of combining home-based transcranial direct current stimulation with mindfulness-based meditation for pain in older adults with knee osteoarthritis: A randomized controlled pilot study. J Clin Neurosci. 2019 Aug 14;: Authors: Ahn H, Zhong C, Miao H, Chaoul A, Park L, Yen IH, Vila MA, Sorkpor S, Abdi S Abstract Transcranial direct current stimulation (tDCS) has been shown to be effective for reducing pain, and a growing body of...
J Clin Neurosci
21h

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