Related ArticlesManagement of epidural hematomas in pediatric patients presenting with a GCS of 14 or better. J Clin Neurosci. 2019 Aug 14;: Authors: Bounajem MT, Samples DC, Wallace DJ, Tavakoli S, Liao L, Tarasiewicz I Abstract OBJECT: Guidelines for the management of pediatric epidural hematoma (PEDH) remain poorly defined. Here we seek to characterize the disease course of PEDH in patients with presenting Glasgow Coma Scale (GCS) of 14+, and suggest...
Related ArticlesPotential predictors of quality of life in Parkinson's Disease: Sleep and mood disorders. J Clin Neurosci. 2019 Aug 14;: Authors: Palmeri R, Lo Buono V, Bonanno L, Sorbera C, Cimino V, Bramanti P, Di Lorenzo G, Marino S Abstract Sleep Disturbances are a non motor symptom very common in Parkinson's Disease characterized by insomnia, worse quality of sleep and Excessive Daytime Sleepiness. Several factors have been associated with these...
Related ArticlesClinical observations on the release of tethered spinal cord in children with intra-operative neurophysiological monitoring: A retrospective study. J Clin Neurosci. 2019 Aug 14;: Authors: Jiang J, Zhang S, Dai C, Jiang X, Niu X, Chen X, Tang F Abstract To study the utility of neurophysiological monitoring in the micro-surgical treatments on children with Tethered Cord Syndrome (TCS). A total of 100 patients were included in this study....
Related ArticlesEfficacy of combining home-based transcranial direct current stimulation with mindfulness-based meditation for pain in older adults with knee osteoarthritis: A randomized controlled pilot study. J Clin Neurosci. 2019 Aug 14;: Authors: Ahn H, Zhong C, Miao H, Chaoul A, Park L, Yen IH, Vila MA, Sorkpor S, Abdi S Abstract Transcranial direct current stimulation (tDCS) has been shown to be effective for reducing pain, and a growing body of...
Related ArticlesSerum lactate level upon admission to the neuro-intensive care unit and 90-day mortality: A retrospective study. J Clin Neurosci. 2019 Aug 13;: Authors: Oh TK, Song IA, Bae HJ, Jeon YT Abstract The serum lactate level is a useful predictor of mortality in critically ill patients. However, little is known about the association between the serum lactate level and mortality in patients admitted to neuro-intensive care units (NCUs). The present...
Related ArticlesNeck disability in patients with cervical spondylosis is associated with altered brain functional connectivity. J Clin Neurosci. 2019 Aug 13;: Authors: Holly LT, Wang C, Woodworth DC, Salamon N, Ellingson BM Abstract Cervical degenerative disease is a major cause of neck disability, but it has been understudied in patients with cervical spondylotic (CS), largely due to the fact that the neurological impairment associated with this condition...
Related ArticlesPrediction of the extent of thrombus formation in the parent artery after endovascular occlusion of a distal anterior cerebral artery aneurysm using computational fluid dynamics. J Clin Neurosci. 2019 Aug 13;: Authors: Tanioka S, Ishida F, Kishimoto T, Tanaka K, Shimosaka S, Suzuki H Abstract Endovascular coiling of a cerebral aneurysm and coil occlusion of the parent artery have been occasionally performed to treat cerebral aneurysms;...
Related ArticlesThe effect of uric acid on sleep quality after acute ischemic stroke. J Clin Neurosci. 2019 Aug 13;: Authors: He W, Qiu H, Zhu J, Feng W, Lin Y, Shu M, He J Abstract Sleep disturbance is a common psychiatric complication after stroke. Oxidative stress has been an important pathophysiological mechanism of sleep disturbance. However, no study has explored the relationship between uric acid (UA) and post-stroke sleep quality. This prospective...
Related ArticlesGraph theory and network topological metrics may be the potential biomarker in Parkinson's disease. J Clin Neurosci. 2019 Aug 13;: Authors: Huang LC, Wu PA, Lin SZ, Pang CY, Chen SY Abstract This study used Voxel-based morphometry (VBM) and resting-state functional magnetic resonance imaging (rs-fMRI) to investigate changes in brain structure and networks functional connectivity, respectively. We tried to identify the potential biomarkers...
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Related ArticlesIdentification of LCN1 as a Potential Biomarker for Breast Cancer by Bioinformatic Analysis. DNA Cell Biol. 2019 Aug 19;: Authors: Yang Y, Li F, Luo X, Jia B, Zhao X, Liu B, Gao R, Yang L, Wei W, He J Abstract The biological functions of lipocalin-1 (LCN1) are involved in innate immune responses and act as a physiological scavenger of potentially harmful lipophilic molecules. However, the relevance of LCN1 with cancer is rarely concerned...
Related ArticlesHER2 heterogeneity is a poor prognosticator for HER2-positive gastric cancer. World J Clin Cases. 2019 Aug 06;7(15):1964-1977 Authors: Kaito A, Kuwata T, Tokunaga M, Shitara K, Sato R, Akimoto T, Kinoshita T Abstract BACKGROUND: The clinical significance of intratumoral human epidermal growth factor receptor 2 (HER2) heterogeneity is unclear for HER2-positive gastric cancer, although it has been reported to be a significant prognosticator...
Related ArticlesA Phase Ib Trial of Durvalumab in Combination with Trastuzumab in HER2-Positive Metastatic Breast Cancer (CCTG IND.229). Oncologist. 2019 Aug 16;: Authors: Chia S, Bedard PL, Hilton J, Amir E, Gelmon K, Goodwin R, Villa D, Cabanero M, Tu D, Tsao M, Seymour L Abstract BACKGROUND: Immune checkpoint inhibitors are active in a broad range of cancers, including programmed death ligand 1 (PD-L1)-positive, triple-negative, metastatic breast...
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Publication date: September 2019Source: International Journal of Psychophysiology, Volume 143Author(s):
Publication date: September 2019Source: International Journal of Psychophysiology, Volume 143Author(s):
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Journal Name: Journal of Pediatric Endocrinology and MetabolismIssue: Ahead of print
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Publication date: 18 November 2019Source: Behavioural Brain Research, Volume 374Author(s):
Publication date: Available online 19 August 2019Source: Behavioural Brain ResearchAuthor(s): Risto Halonen, Liisa Kuula, Jari Lahti, Tommi Makkonen, Katri Räikkönen, Anu-Katriina PesonenAbstractA common single nucleotide polymorphism (SNP) of the brain-derived neurotrophic factor (BDNF) gene, Val66Met, has been reported to impair BDNF secretion and memory function. However, few studies have investigated the interaction of BDNF genotype and sleep characteristics, such as sleep spindles, that promote...
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Related ArticlesEvaluation of the masticatory muscle function, physiological sleep variables, and salivary parameters after electromechanical therapeutic approaches in adult patients with Down syndrome: a randomized controlled clinical trial. Trials. 2019 Apr 11;20(1):215 Authors: Giannasi LC, Dutra MTS, Tenguan VLS, Mancilha GP, Silva GRC, Fillietaz-Bacigalupo E, da Silva DB, Politti F, Nacif SR, de Oliveira EF, da Rocha JC, Rocha CT, Romero MM, de Oliveira CS, de...
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4291 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2019/08/20PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Related ArticlesFunctionalized selenium nanoparticles enhance the anti-EV71 activity of oseltamivir in human astrocytoma cell model. Artif Cells Nanomed Biotechnol. 2019 Dec;47(1):3485-3491 Authors: Zhong J, Xia Y, Hua L, Liu X, Xiao M, Xu T, Zhu B, Cao H Abstract Enterovirus 71 (EV71) which commonly caused the hand-foot-mouth disease (HFMD) has become one of public health challenges worldwide. However, no effective vaccines or drugs for this disease...
Related ArticlesIntegrated metabolomics and 16S rRNA sequencing to investigate the regulation of Chinese yam on antibiotic-induced intestinal dysbiosis in rats. Artif Cells Nanomed Biotechnol. 2019 Dec;47(1):3382-3390 Authors: Sun Y, Liu T, Si Y, Cao B, Zhang Y, Zheng X, Feng W Abstract Objective: Antibiotics have saved hundreds of millions of patient's lives, but there are also many side effects. This paper mainly studies the regulation of Chinese yam...
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Related ArticlesClinical efficacy of herbal extracts in treatment of mild to moderate acne vulgaris: A 8-week, double-blinded, randomized, controlled trial. J Dermatolog Treat. 2019 Aug 19;:1-16 Authors: Yang JH, Moon J, Yoon JY, Kim JW, Choi S, Cho SI, Hwang EJ, Suh DH Abstract Background: Herbal extracts with fewer adverse effects can be an alternative to these drugs because they can target various molecular pathways of acne pathogenesis. Objectives:...
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58 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human homeostasis These pubmed results were generated on 2019/08/20PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Publication date: Available online 20 August 2019Source: Human PathologyAuthor(s): Josephine Kamtai Dermawan, Sanjay Mukhopadhyay, Akeesha Alia ShahSummaryThe absence of cytokeratin expression in paraganglioma helps to differentiate it from other neuroendocrine neoplasms such as carcinoid tumor. Although rare cytokeratin positive paragangliomas have been reported, there are no large systematic studies of this phenomenon. The aim of this study was to determine the frequency and extent of cytokeratin...
Publication date: Available online 20 August 2019Source: Human PathologyAuthor(s): Marion Beaumont, Frédéric Dugay, Solène-Florence Kammerer-Jacquet, Sylvie Jaillard, Florian Cabillic, Romain Mathieu, Gregory Verhoest, Karim Bensalah, Nathalie Rioux-Leclercq, Marc-Antoine Belaud-Rotureau, the members of CARARE french network Rare Renal Carcinoma in Adults of the INCa National Institut of Cancer, FranceSummaryRenal cell carcinomas (RCC) are divided in several subtypes, characterized by morphological...
Publication date: Available online 20 August 2019Source: Human PathologyAuthor(s): Pooja Navale, Lisa M. Rooper, Justin A. Bishop, William H. WestraSummaryThe designation “mucoepidermoid tumor” is a historic one used in reference to a form of mucoepidermoid carcinoma (MEC) that was believed to be benign. This bygone notion was based on the observation that the vast majority of MECs arising from the intraoral minor salivary glands behave in a benign fashion, particularly when they do not exhibit high...
Publication date: Available online 19 August 2019Source: Human PathologyAuthor(s): Deyin Xing, Yuehua Liu, Hyeon Jin Park, Inji Baek, Hung Tran, Gloria Cheang, Jorge Novo, Jessica Dillon, Andres Matoso, Emily Farmer, Max A. Cheng, Ya-Chea Tsai, Kara Lombardo, Michael G. Conner, Russell Vang, Chien-Fu Hung, T.-C. Wu, Wei SongUsing a comprehensive next-generation sequencing pipeline (143 genes), Oncomine Comprehensive v.2, we analyzed genetic alterations on a set of vulvar squamous cell carcinomas...
Publication date: Available online 19 August 2019Source: Human PathologyAuthor(s): Maryam Shahi, Stephen J. Bloechl, Rachel I. Vogel, Rupendra Shrestha, Hannah R. Krigman, Maria Evasovich, Lynn A Burmeister, Khalid AminAbstractMolecular diagnostics increasingly direct the management of thyroid nodules with an indeterminate cytologic diagnosis. This study was undertaken to correlate cytomorphologic features with the molecular profiles in an effort to identify features predictive of molecular aberrations....
Publication date: Available online 19 August 2019Source: Human PathologyAuthor(s): Thalita Santana, Andrle Pavel, Petr Martinek, Petr Steiner, Petr Grossmann, Martina Baněčková, Alena SkalovaSummarySalivary duct carcinoma (SDC) is one of the most aggressive salivary gland tumors and prognosis remains poor for most patients. The aim of this study was to investigate the prognostic implications of biomarker immunoprofile in a cohort of SDC and to identify molecular characteristics through next-generation...
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Related ArticlesImpact of Intermittent Pringle Maneuver on Long-Term Survival After Hepatectomy for Hepatocellular Carcinoma: Result from Two Combined Randomized Controlled Trials. World J Surg. 2019 Aug 16;: Authors: Lee KF, Chong CCN, Cheung SYS, Wong J, Fung AKY, Lok HT, Lai PBS Abstract BACKGROUND: Hepatectomy remains an important curative treatment for hepatocellular carcinoma (HCC). Intermittent Pringle maneuver (IPM) is commonly applied during...
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Related ArticlesContribution of adenosine and ATP to the carotid body chemosensory activity in ageing. J Physiol. 2019 Aug 19;: Authors: Sacramento JF, Olea E, Ribeiro MJ, Prieto-Lloret J, Melo BF, Gonzalez C, Martins FO, Monteiro EC, Conde SV Abstract KEY POINTS: Adenosine and ATP are excitatory neurotransmitters involved in the carotid body (CB) response to hypoxia. During ageing the CB exhibits a decline in its functionality, demonstrated by decreased...
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27 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "BMJ Open"[jour] These pubmed results were generated on 2019/08/20PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Related ArticlesBrain oxidative stress in rat with chronic iron or copper overload. J Inorg Biochem. 2019 Aug 06;199:110799 Authors: Sebio RM, Ferrarotti N, Lairion F, Magriñá CS, Fuda J, Torti H, Boveris A, Repetto MG Abstract Male rats of 80-90 g that were fed 42 days with a commercial rodent diet of 2780 kcal/100 g and received chronic overloads of either Fe(II) or Cu(II) in the drinking water. The two metals produced brain oxidative stress and damage...
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Publication date: Available online 19 August 2019Source: Hearing ResearchAuthor(s): Krishna Bommakanti, Janani S. Iyer, Konstantina M. StankovicAbstractSensorineural hearing loss (SNHL) is an extraordinarily common disability, affecting 466 million people across the globe. Half of these incidents are attributed to genetic mutations that disrupt the structure and function of the cochlea. The human cochlea’s interior cannot be imaged or biopsied without damaging hearing; thus, everything known about...
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Related ArticlesPetrous apex non-secretory plasma cell myeloma with aberrant cytokeratin expression. J Histotechnol. 2019 Aug 19;:1-4 Authors: Badr-El-Dine M, Abdelzaher E, Eid M, Elshennawy R Abstract Multiple myeloma is a monoclonal proliferation of plasma cells with common involvement of vertebrae, ribs and skull vault. However, involvement of skull base is relatively uncommon and myeloma manifesting initially as a petrous apex mass is distinctly...
Related Articles[Tumors of glomus vagale: diagnostics and therapy]. Orv Hetil. 2019 Aug;160(34):1358-1362 Authors: Iszlai Z, Szövördi É, Karosi T Abstract Introducing the diagnostic protocol and therapy of a rare disease reviewing the worldwide literature named as vagal paraganglioma is our main target. This type is specific for women of middle age, and it is appearing as a unilateral neck mass, with or without Fontaine's sign. Giving a heavy aspect...
Related ArticlesEsthesioneuroblastoma: Summary of Single-center Experiences with Focus on Adjuvant Therapy and Overall Survival. Cureus. 2019 Jun 13;11(6):e4897 Authors: Alotaibi HA, Priola SM, Bernat AL, Farrash F Abstract Esthesioneuroblastoma (ENB) is a rare malignant tumor of the nasal cavity. The genetic basis of its development is still under study and has not been fully delineated. It has varying symptoms depending on the lesion's location within...
Related ArticlesNasogastric Tube Feeding into the Brain After Endoscopic Endonasal Transsphenoidal Surgery. World Neurosurg. 2019 Aug 14;: Authors: Zhang X, Ji T, Chen L, Yang J, Huang G Abstract Endoscopic endonasal transsphenoidal (EET) approach for skull base tumors has become increasingly popular. We know that bone defects in the skull base can cause cerebrospinal fluid rhinorrhea, but for patients who need to be intubated through the nose, the tube...
Related ArticlesClinical efficacy of optical coherence tomography to predict the visual outcome after endoscopic endonasal surgery for suprasellar tumors. World Neurosurg. 2019 Aug 14;: Authors: Jeon C, Park KA, Hong SD, Choi JW, Seol HJ, Nam DH, Lee JI, Shin HJ, Kong DS Abstract OBJECTIVE: Prediction of visual outcome following endoscopic endonasal tumor resection still remains a challenge. We investigated the prognostic value of preoperative peripapillary...
Related ArticlesSimplified Dural Reconstruction Procedure Using Biocompatible Polyglycolic Acid Felt with Autologous Abdominal Fat Grafts after a Transpetrosal Approach. World Neurosurg. 2019 Aug 14;: Authors: Yamaguchi S, Terasaka S, Okamoto M, Ishi Y, Motegi H, Kobayashi H, Houkin K Abstract OBJECTIVE: Dural reconstruction after transpetrosal approaches is complicated because complete primary closure of presidmoid dura mater is difficult to achieve....
Related ArticlesEffect of rapid maxillary expansion on the morphology of spheno-occipital synchondrosis in rats : A micro-CT study. J Orofac Orthop. 2019 Aug 16;: Authors: Strzecki A, Osiewacz S, Szczepańska J, Pawłowska E Abstract PURPOSE: Spheno-occipital synchondrosis (SOS) plays a significant role in the anterior growth of the midface. Orthopaedic forces acting during rapid maxillary expansion (RME) are transferred to the skull base and thus could...
Related ArticlesEstablishment of normative values for the fetal posterior fossa by magnetic resonance imaging. Prenat Diagn. 2018 12;38(13):1035-1041 Authors: Chapman T, Menashe SJ, Zare M, Alessio AM, Ishak GE Abstract OBJECTIVE: Suspected Dandy-Walker continuum anomalies constitute a significant percentage of prenatal cases evaluated by magnetic resonance imaging (MRI). To unify the description of posterior fossa malformations, we sought to establish...
Related ArticlesNovel technique of a multifunctional electrosurgical system for minimally invasive surgery. J Neurosurg. 2017 Mar;126(3):997-1002 Authors: Mittelstein D, Deng J, Kohan R, Sadeghi M, Maarek JM, Zada G Abstract Bipolar electrosurgery in the minimally invasive endoscopic surgery theater has been traditionally limited to the use of standard bipolar forceps, which are minimally versatile, have a limited range of motion, and are associated...
Related ArticlesStatPearls Book. 2019 01 Authors: Abstract The middle cranial fossa, also known as the central skull base, is an intricate intracranial area that contains many structures susceptible to pathology, making it an area directly pertinent to neurosurgeons, neurologists, otolaryngologists, ophthalmologists, radiologists, and endocrinologists.[1][2] The middle cranial fossa can be divided into medial and lateral portions, each containing many nerves, vessels,...
Related ArticlesStatPearls Book. 2019 01 Authors: Abstract The spinal cord is a cylindrical well-organized structure. It begins at the foramen magnum as a continuation of the medulla oblongata at the base of the skull. It located within the vertebral or spinal canal. In men, it extends up to 45 cm and in women up to 43 cm. The spinal cord divides into 31 segments: cervical 8, thoracic 12, lumbar 5, sacral 5, and coccygeal 1. These segments consist of 31 pairs of spinal...
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Journal Name: Clinical Chemistry and Laboratory Medicine (CCLM)Issue: Ahead of print
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Publication date: Available online 19 August 2019Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Jennifer A. Brooks, Michael J. Cunningham, Jeffrey A. Koempel, Kosuke Kawai, Jonathan K. Huang, Rachel E. Weitzman, Beth Osterbauer, Amy L. HughesAbstractIntroductionA Sistrunk procedure is the standard operative management of patients with thyroglossal duct cysts. Drain placement is commonly employed with the goal of reducing postoperative complications. This study investigates...
Publication date: Available online 19 August 2019Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Ying Chen, Yun Li, Yan Ren, Haifeng Li, Meiping Huang, Huan Jia, Tao Yang, Zhaoyan Wang, Zhiwu Huang, Hao Wu
Publication date: Available online 19 August 2019Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Steven M. Andreoli, Brooke L. Wilson, Catherine SwansonAbstractObjectivesNeuromuscular electrical stimulation (NMES) therapy in the head and neck has been effectively used to rehabilitate swallowing in adult patients with acquired dysphagia. Limited data is available for the effectiveness of NMES in medically complex children with dysphagia and aspiration. This study intends to...
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Publication date: Available online 19 August 2019Source: Clinical Neurology and NeurosurgeryAuthor(s): Tomáš Krejčí, Petr Vacek, Ondřej Krejčí, Martin Chlachula, Silvia Szathmaryová, Lipina RadimABSTRACTObjectiveCysts of the Cavum septi pellucidi (CSP), cavum vergae (CV) and cavum veli interpositi (CVI) are anterior midline intracranial findings which are typically incidental – only rarely do we encounter symptomatic cysts of this type. Only a quite small number of these cysts series have been published,...
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Publication date: Available online 19 August 2019Source: Journal of Cranio-Maxillofacial SurgeryAuthor(s): Mohammad Zandi, Arash Dehghan, Ideh Talimkhani, Leila Rezaeian, Naser Mohammad Gholi MezerjiAbstractObjectiveThis study aims to evaluate the healing process of autografted mandibular bone defects in rats treated with zoledronate (ZOL).Subjectsand methods: A total of 180 Wistar rats were divided into four groups: group L received intravenous infusion of two doses of 0.06 mg/kg ZOL, nine weeks...
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Publication date: Available online 19 August 2019Source: Pathology - Research and PracticeAuthor(s): Ping Wang, Yangyang Du, Jingfen WangAbstractBackgroundBreast cancer is the most frequent carcinoma in females, which could be classified to 4 subtypes and the current treatment is still far from satisfactory. In this study, we explored the effects of autophagy inhibition on certain subtypes of breast cancer and the molecular mechanism underlying the different response for breast cancer subtypes initially.MethodsAutophagy...
Publication date: Available online 19 August 2019Source: Pathology - Research and PracticeAuthor(s): Hui Wang, Rani KanthanAbstractAmoebiasis, caused by the intestinal protozoan Entamoeba histolytica, though a relatively common parasitic disease in the tropical and subtropical regions, is uncommon in the developed countries. In these countries, as amoebic colitis shares similar clinical symptoms and endoscopic features with inflammatory bowel disease (IBD), these cases can be easily unrecognized...
Publication date: Available online 19 August 2019Source: Pathology - Research and PracticeAuthor(s): Juliana Mançano Melhado Brod, Patricia Lourenção, Flávia Pedreira Pereira, Icléia Siqueira Barreto, Marcelo Sperandio, Vera C. Araújo, Andresa B. Soares, Ana Cláudia Garcia Rosa
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Related Articles3D Kinematic Gait Analysis for Preclinical Studies in Rodents. J Vis Exp. 2019 Aug 03;(150): Authors: Wong J, Shah PK Abstract The utility of three-dimensional (3D) kinematic motion analysis systems is limited in rodents. Part of the reason for this inadequacy is the use of complex algorithms and mathematical modeling that accompany 3D data collection and analysis procedures. This work provides a simple, user-friendly, step-by-step detailed...
Related ArticlesPresynapse Formation Assay Using Presynapse Organizer Beads and "Neuron Ball" Culture. J Vis Exp. 2019 Aug 02;(150): Authors: Parvin S, Takeda R, Sasaki Y Abstract During neuronal development, synapse formation is an important step to establish neural circuits. To form synapses, synaptic proteins must be supplied in appropriate order by transport from cell bodies and/or local translation in immature synapses. However, it is not fully...
Related ArticlesAn In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota. J Vis Exp. 2019 Jul 31;(149): Authors: Ahmadi S, Wang S, Nagpal R, Mainali R, Soleimanian-Zad S, Kitzman D, Yadav H Abstract The emerging role of the gut microbiome in several human diseases demands a breakthrough of new tools, techniques and technologies. Such improvements are needed to decipher the utilization of microbiome...
Related ArticlesIn Vivo Surface Electrocardiography for Adult Zebrafish. J Vis Exp. 2019 Aug 01;(150): Authors: Zhao Y, Yun M, Nguyen SA, Tran M, Nguyen TP Abstract The electrocardiogram waveforms of adult zebrafish and those of humans are remarkably similar. These electrocardiogram similarities enhance the value of zebrafish not only as a research model for human cardiac electrophysiology and myopathies but also as a surrogate model in high throughput...
Related ArticlesAn Antibody Feeding Approach to Study Glutamate Receptor Trafficking in Dissociated Primary Hippocampal Cultures. J Vis Exp. 2019 Aug 02;(150): Authors: Chiu AM, Barse L, Hubalkova P, Sanz-Clemente A Abstract Cellular responses to external stimuli heavily rely on the set of receptors expressed at the cell surface at a given moment. Accordingly, the population of surface-expressed receptors is constantly adapting and subject to strict...
Related ArticlesDual Bioluminescence Imaging of Tumor Progression and Angiogenesis. J Vis Exp. 2019 Aug 01;(150): Authors: Zhang K, Wang C, Wang R, Chen S, Li Z Abstract Angiogenesis, as a crucial process of tumor progression, has become a research hotspot and target of anti-tumor therapy. However, there is no reliable model for tracing tumor progression and angiogenesis simultaneously in a visual and sensitive manner. Bioluminescence imaging displays...
Related ArticlesIn Vitro Assay to Study Tumor-macrophage Interaction. J Vis Exp. 2019 Aug 01;(150): Authors: An Z, Weiss WA Abstract Tumor associated macrophages (TAMs) account for a large percentage of cells in the tumor mass for different types of cancers. Glioblastoma (GBM), a malignant brain tumor with no cure, has up to a half the tumor mass TAMs. TAMs can be pro-tumoral or anti-tumoral, depending on the activation of specific genes in the cells....
Related ArticlesFabrication of Microscope Stage for Vertical Observation with Temperature Control Function. J Vis Exp. 2019 Jul 31;(149): Authors: Matsukawa Y, Ide Y, Umemura K Abstract Samples are usually placed onto a horizontal microscope stage for microscopic observation. However, to observe the influence of gravity on a sample or study afloat behavior, it is necessary to make the microscope stage vertical. To accomplish this, a sideways inverted...
Related ArticlesPre-clinical Model of Cardiac Donation after Circulatory Death. J Vis Exp. 2019 Aug 02;(150): Authors: Aceros H, Joulali L, Borie M, Ribeiro RVP, Badiwala MV, Der Sarkissian S, Noiseux N Abstract Cardiac transplantation demand is on the rise; nevertheless, organ availability is limited due to a paucity of suitable donors. Organ donation after circulatory death (DCD) is a solution to address this limited availability, but due to a period...
Related ArticlesImproving the Accuracy of Flow Cytometric Assessment of Mitochondrial Membrane Potential in Hematopoietic Stem and Progenitor Cells Through the Inhibition of Efflux Pumps. J Vis Exp. 2019 Jul 30;(149): Authors: Morganti C, Bonora M, Ito K Abstract As cellular metabolism is a key regulator of hematopoietic stem cell (HSC) self-renewal, the various roles played by the mitochondria in hematopoietic homeostasis have been extensively studied...
Related ArticlesYeast As a Chassis for Developing Functional Assays to Study Human P53. J Vis Exp. 2019 Aug 04;(150): Authors: Monti P, Bosco B, Gomes S, Saraiva L, Fronza G, Inga A Abstract The finding that the well-known mammalian P53 protein can act as a transcription factor (TF) in the yeast S. cerevisiae has allowed for the development of different functional assays to study the impacts of 1) binding site [i.e., response element (RE)] sequence variants...
Related ArticlesModeling the Size Spectrum for Macroinvertebrates and Fishes in Stream Ecosystems. J Vis Exp. 2019 Jul 30;(149): Authors: McGarvey DJ, Woods TE, Kirk AJ Abstract The size spectrum is an inverse, allometric scaling relationship between average body mass (M) and the density (D) of individuals within an ecological community or food web. Importantly, the size spectrum assumes that individual size, rather than species' behavioral or life history...
Related ArticlesRabies Necropsy Techniques in Large and Small Animals. J Vis Exp. 2019 Jul 30;(149): Authors: Jarvis JA, Brown KT, Appler KA, Fitzgerald DP, Davis AD Abstract The New York State Department of Health (NYSDOH) Rabies Laboratory receives between 6,000 to 9,000 specimens annually and performs rabies testing for the entire state, with the exception of New York City. The Rabies laboratory necropsies a variety of animals ranging in size from...
Related ArticlesElectrophysiological Recordings of Single-cell Ion Currents Under Well-defined Shear Stress. J Vis Exp. 2019 Aug 02;(150): Authors: Fancher IS, Levitan I Abstract Fluid shear stress is well known to play a major role in endothelial function. In most vascular beds, elevated shear stress from acute increases in blood flow triggers a signaling cascade resulting in vasodilation thereby alleviating mechanical stress on the vascular wall. The...
Related ArticlesIntroducing a Gene Knockout Directly Into the Amastigote Stage of Trypanosoma cruzi Using the CRISPR/Cas9 System. J Vis Exp. 2019 Jul 31;(149): Authors: Akutsu Y, Doi M, Furukawa K, Takagi Y Abstract Trypanosoma cruzi is a pathogenic protozoan parasite that causes Chagas' disease mainly in Latin America. In order to identify a novel drug target against T. cruzi, it is important to validate the essentiality of the target gene in the mammalian...
Related ArticlesE-Patient Counseling Trial (E-PACO): Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy. J Vis Exp. 2019 Aug 01;(150): Authors: Veldhuijzen G, van Esch AA, Klemt-Kropp M, Terhaar Sive Droste JS, Drenth JPH Abstract Improving patient education focusing on bowel preparation before a colonoscopy leads to cleaner colons. Endoscopy units must obtain informed consent and perform a risk assessment for sedative...
Related ArticlesEvaluation of Hemisphere Lateralization with Bilateral Local Field Potential Recording in Secondary Motor Cortex of Mice. J Vis Exp. 2019 Jul 31;(149): Authors: Chen Y, Li M, Zheng Y, Yang L Abstract This article demonstrates complete, detailed procedures for both in vivo bilateral recording and analysis of local field potential (LFP) in the cortical areas of mice, which are useful for evaluating possible laterality deficits, as well...
Related ArticlesScalable Quantum Integrated Circuits on Superconducting Two-Dimensional Electron Gas Platform. J Vis Exp. 2019 Aug 02;(150): Authors: Delfanazari K, Ma P, Puddy R, Yi T, Cao M, Gul Y, Richardson CL, Farrer I, Ritchie D, Joyce HJ, Kelly MJ, Smith CG Abstract To form a coherent quantum transport in hybrid superconductor-semiconductor (S-Sm) junctions, the formation of a homogeneous and barrier-free interface between two different materials...
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Publication date: Available online 19 August 2019Source: World NeurosurgeryAuthor(s): Taketoshi Maehara, Kazuko Kamiya, Takamitsu Fujimaki, Akira Matsumura, Kazuhiro Hongo, Satoshi Kuroda, Mitsunori Matsumae, Hideo Takeshima, Nobuo Sugo, Naoyuki Nakao, Nobuhito Saito, Fusao Ikawa, Noriko Tamura, Kaori Sakurada, Shoko Shimokawa, Hajime Arai, Kaoru Tamura, Kazutaka Sumita, Shoko Hara, Yoko KatoAbstractObjectiveTo analyze why women quit full-time employment as neurosurgeons and to discuss the conditions...
Publication date: Available online 19 August 2019Source: World NeurosurgeryAuthor(s): Charles A. Miller, John J. Delaney, A. Jesse Schuette
Publication date: Available online 19 August 2019Source: World NeurosurgeryAuthor(s): Nicola Romano, Aldo Fischetti, Margherita Federici, Antonio Castaldi
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134 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: head and neck These pubmed results were generated on 2019/08/20PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
134 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: head and neck These pubmed results were generated on 2019/08/20PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Publication date: Available online 19 August 2019Source: Academic RadiologyAuthor(s): Andreu F. Costa, Kris Peet, Mohamed AbdolellRationale and ObjectivesTo compare the magnitude and interpatient variability in normalized mean hepatic enhancement (MHE) indices when dosing contrast media (CM) according to total body weight (TBW) and lean body weight (LBW).Materials and MethodsThis ethics-approved stratified randomized controlled study allocated 280 outpatients for abdominal Computed Tomography (CT)...
Publication date: Available online 19 August 2019Source: Academic RadiologyAuthor(s): Maryam Ghadimi Mahani
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Related ArticlesDifferential response of SHH-expressing adult medulloblastomas to the sonic hedgehog inhibitor vismodegib: whole-genome analysis. Cancer Biol Ther. 2019 Aug 18;:1-5 Authors: Lou E, Nelson AC, Kool M Abstract Medulloblastoma is an aggressive primitive neuroectodermal tumor of the cerebellum that is more common in children than in adults. In the past decade, advances in understanding the molecular drivers of medulloblastoma have identified...
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