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Τετάρτη 7 Αυγούστου 2019


Efficacy and safety of pembrolizumab as first-line therapy in advanced non-small cell lung cancer with at least 50% PD-L1 positivity: a multicenter retrospective cohort study (HOPE-001)
Summary Objectives As first line therapy, pembrolizumab provides longer progression free survival (PFS) and overall survival (OS) than platinum doublets in programmed death ligand 1 (PD-L1)-positive non-small cell lung cancer (NSCLC) with tumor propensity scores (TPS) ≥50%. However, clinical trials do not represent real-world patients. Materials and Methods This multicenter retrospective study conducted across 11 medical centers in Japan analyzed clinical data from patients receiving...
Latest Results for Investigational New Drugs
11h
Correction to: Inhibitory effects of tea polyphenols by targeting cyclooxygenase-2 through regulation of nuclear factor kappa B, Akt and p53 in rat mammary tumors
The authors regret to inform that there were unknowing errors in figures. The corrected images are given below. These figures are not affecting the results and conclusion of the manuscript. Hence, the text in original paper remains unchanged.
Latest Results for Investigational New Drugs
17h
Targeted Temperature Management: Quantifying the Extent of Serum Electrolyte and Blood Glucose Shifts in Postcardiac Arrest Patients
Therapeutic Hypothermia and Temperature Management, Ahead of Print.
Therapeutic Hypothermia and Temperature Management
9m
Treatment of Bowen’s disease with photodynamic therapy. Observational study in 171 patients with 5-aminolaevulinic acid (BF-200 ALA) and methyl aminolaevulinate (MAL)
Publication date: Available online 6 August 2019Source: Photodiagnosis and Photodynamic TherapyAuthor(s): Sergio Alique-García, Daniel Alique, Jaime Company-Quiroga, Alberto Sánchez, Almudena Hernández Núñez, J. BorbujoAbstractAn observational study was carried out in the photodynamic therapy (PDT) section of Fuenlabrada’s hospital (Madrid, Spain). Our goal was to investigate the efficacy and safety of PDT in Bowen’s disease (BD). Between June 2011-June 2017 171 patients (191 lesions) with diagnosis...
ScienceDirect Publication: Photodiagnosis and Photodynamic Therapy
19h
Hand motor functions on the presence of red fluorescent dental biofilm in older community-dwelling Koreans
Publication date: Available online 6 August 2019Source: Photodiagnosis and Photodynamic TherapyAuthor(s): Na-Ri Shin, Yeo-Jin Yi, Jun-Seon ChoiAbstractBackgroundThe Quantitative Light-induced Fluorescence-Digital (QLF-D) system visualizes old and mature dental biofilm as red fluorescence. Risk factors for poor oral hygiene have been identified, however, few studies have evaluated the relationship between mature dental biofilm and hand motor functions. This study aimed to investigate the effects of...
ScienceDirect Publication: Photodiagnosis and Photodynamic Therapy
19h
Continuous infusion of physostigmine in patients with perioperative septic shock: A pharmacokinetic/pharmacodynamic study with population pharmacokinetic modeling
Publication date: October 2019Source: Biomedicine & Pharmacotherapy, Volume 118Author(s): Nadine Pinder, Johannes B. Zimmermann, Silke Gastine, Gudrun Würthwein, Georg Hempel, Thomas Bruckner, Torsten Hoppe-Tichy, Markus A. Weigand, Stefanie SwobodaAbstractBackgroundIn the context of the cholinergic anti-inflammatory pathway, the clinical trial Anticholium® per Se (EudraCT Number: 2012-001650-26, ClinicalTrials.gov NCT03013322) addressed the possibility of taking adjunctive physostigmine salicylate...
Biomedicine & Pharmacotherapy
16h
MiR-150 attenuates LPS-induced acute lung injury via targeting AKT3
Publication date: October 2019Source: International Immunopharmacology, Volume 75Author(s): Pibao Li, Yanfen Yao, Yuezhen Ma, Yanbin ChenAbstractAcute lung injury (ALI) and its severe manifestation of acute respiratory distress syndrome (ARDS) in human lung are induced by inflammatory cytokines and endogenous factors such as miRNAs. However, the role of miR-150 in lipopolysaccharide (LPS)-induced ALI is not clear. Here, we found miR-150 expression was significantly reduced in the serum of patients...
ScienceDirect Publication: International Immunopharmacology
17h
Regulating Osteogenic Differentiation by Suppression of Exosomal MicroRNAs
Tissue Engineering Part A, Volume 25, Issue 15-16, Page 1146-1154, August 2019.
Tissue Engineering
12m
Correction to: Biological and Mechanical Factors Promote the Osteogenesis of Rabbit Artificial Vertebral Laminae: A Comparison Study by Li L, Chen X, He Y, Dong Y. Tissue Eng Part A 2018;24(13-14):1082–1090. DOI: 10.1089/ten.tea.2017.0426
Tissue Engineering Part A, Volume 25, Issue 15-16, Page 1189-1189, August 2019.
Tissue Engineering
12m
Multisite Injection of Bioengineered Hepatic Units from Collagen Hydrogel and Neonatal Liver Cells in Parenchyma Improves Liver Cirrhosis
Tissue Engineering Part A, Volume 25, Issue 15-16, Page 1167-1174, August 2019.
Tissue Engineering
12m
Correction to: NELL-1, HMGB1, and CCN2 Enhance Migration and Vasculogenesis, But Not Osteogenic Differentiation Compared to BMP2 by Fahmy-Garcia S, van Driel M, Witte-Buoma J, Walles H, van Leeuwen JPTM, van Osch GJVM, and Farrell E. Tissue Eng Part A 2018;24(3-4):207-218. DOI: 10.1089/ten.tea.2016.0537
Tissue Engineering Part A, Volume 25, Issue 15-16, Page 1188-1188, August 2019.
Tissue Engineering
12m
Correction to: The Role of Continuous Cerebrospinal Fluid Pulsation Stress in the Remodeling of Artificial Vertebral Laminae: A Comparison Experiment by Li L, He Y, Chen X, Dong Y. Tissue Eng Part A 2019;25(3–4):203–213. DOI: 10.1089/ten.tea.2018.0100
Tissue Engineering Part A, Volume 25, Issue 15-16, Page 1190-1190, August 2019.
Tissue Engineering
12m
Regenerative Medicine: “Are We There Yet?”
Tissue Engineering Part A, Volume 25, Issue 15-16, Page 1067-1071, August 2019.
Tissue Engineering
12m

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