Publication date: Available online 22 August 2019Source: Data in BriefAuthor(s): James Donohue, Edward Kerwin, Sanjay Sethi, Brett Haumann, Srikanth Pendyala, Lorna Dean, Chris N. Barnes, Edmund J. Moran, Glenn CraterAbstractThis article contains information on the experimental design and methods on how the safety and tolerability data concerning patients with moderate to very severe chronic obstructive pulmonary disease (COPD) were obtained. This is in addition to our original research article....
Publication date: Available online 22 August 2019Source: Data in BriefAuthor(s): Praveen Kolar, John Classen, Steven G. HallAbstractThere is a renewed interest in treating odorous contaminants such as butyric acid, p-cresol, and ammonia that are emitted from animal farming operations. However, developing newer treatment technologies require quantitative information regarding the properties of the target pollutants. Therefore, in this communication, baseline data related to physicochemical and thermodynamic...
Publication date: Available online 22 August 2019Source: Data in BriefAuthor(s): Carlos S. Osorio-González, Krishnamoorthy Hegde, Satinder K. Brar, Azadeh Kermanshahipour, Antonio Avalos-RamírezAbstractLignocellulosic biomass is a promising alternative for the replacement of limited fossil resources to produce various chemical compounds, such as 5-hydroxymethylfurfural, furfural, vanillin, vanillic acid, ferulic acid, syringaldehyde, and 4-aminobenzoic acid. However, the complex biomass structure...
Publication date: Available online 22 August 2019Source: Data in BriefAuthor(s): Theo Lynn, Patricia Takako Endo, Pierangelo Rosati, Ivanovitch Silva, Guto Leoni Santos, Debbie GingAbstractThe data set is composed of 2,285 definitions posted on the Urban Dictionary platform from 1999 to May 2016. The data was classified as misogynistic and non- misogynistic by three independent researchers with domain knowledge. The data set is available in public repository in a table containing two columns: the...
Publication date: Available online 22 August 2019Source: Data in BriefAuthor(s): Hafiz Tayyab Rauf, Basharat Ali Saleem, M. Ikram Ullah Lali, Muhammad Attique Khan, Muhammad Sharif, Syed Ahmad Chan BukhariAbstractPlants are as vulnerable by diseases as animals. Citrus is a major plant grown mainly in the tropical areas of the world due to its richness in vitamin C and other important nutrients. The production of the citrus fruit has been widely affected by citrus diseases which ultimately degrades...
Publication date: Available online 22 August 2019Source: Data in BriefAuthor(s): Giulia Petroni, Matteo Stefanini, Serena Pillozzi, Olivia Crociani, Andrea Becchetti, Annarosa ArcangeliAbstractMacrolide antibiotics, such as Clarithromycin (Cla), have been proven to exert anti-tumour activity in several preclinical models of different types of cancer. Cla can exert its anti-tumour effects through different mechanisms, e.g. by blocking the autophagic flux, inducing apoptosis or inhibiting tumour-induced...
Publication date: Available online 22 August 2019Source: Data in BriefAuthor(s): Huazhi Chen, Yu Du, Cuiling Xiong, Yanzhen Zheng, Dafu Chen, Rui GuoAbstractHoneybees are pivotal pollinators of crops and wild flora, and of great importance in supporting critical ecosystem balance. Nosema ceranae, a unicellular fungal parasite that infects midgut epithelial cells of honeybees, can dramatically reduce honeybee population and productivity. Here, midguts of Apis mellifera ligustica workers at 7 d and...
Publication date: Available online 22 August 2019Source: Data in BriefAuthor(s): Adam Souid, Mohamed Esaker, David Elliott, Omar HamzaAbstractThe provision of suitable incubation environments is vital for successful implementation of bio self-healing concrete (bio-concrete). We investigated the effect of soil incubation to examine if the self-healing process can be activated in comparison with the conventional incubation environment (water). The data was collected from laboratory-scale experiments...
Publication date: Available online 22 August 2019Source: Data in BriefAuthor(s): Joseane Bortolanza de Oliveira, Flavio Santana Michels, Elaine Silva de Pádua Melo, Carlos Eduardo Domingues Nazário, Anderson Rodrigues Lima Caires, Daniel Araujo Gonçalves, Claudia Andrea Lima Cardoso, Valter Aragão do NascimentoAbstractDersani® and sunflower® oils are used by the Brazilian population as a cicatrizing agent. However, data on physical and chemical properties of these oils are scarce. In this data article...
Publication date: Available online 22 August 2019Source: Data in BriefAuthor(s): Golan Yeganeh, Bahman Ramavandi, Hossein Esmaeili, Sajad TamjidiAbstractIn this dataset, the removal of ammonia from synthetic and real wastewater was studied using the Ziziphus spina-christi activated carbon (ZSAC) and the biochar of Sargassum oligocystum (BSO). Several analyses such as FTIR, SEM, EDS, XRD, and BET were used to determine the physical and surface properties of the adsorbents. The BET analysis showed...
Publication date: Available online 22 August 2019Source: Data in BriefAuthor(s): Devangana Bhuyan, George Warren Greene, Ratul Kumar DasAbstractThe dataset presents the synthesis and physicochemical characterization of blank and curcumin encapsulated sericin protein nanoparticles obtained from Philosamia ricini (also known as Ahimsa silk or Peace silk or Eri). Reports on application of sericin protein obtained from P. ricini are scanty at best. Sericin was extracted from the cocoons by high temperature...
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- Jennifer Middleton, MD, MPHA compelling Close-Ups in the August 15 issue of AFP shares the story of "DN," a patient recently released from prison with hepatitis C. DN reports excellent treatment outcomes after his family doctor treated his hepatitis C. He was able to avoid "going to see an expensive subspecialist I didn't know," and the persistence of his family physician and her office team helped DN overcome his struggles with keeping appointments and adhering to his medication regimen. Recent...
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Cancers, Vol. 11, Pages 1247: Multifaceted Regulation of PTEN Subcellular Distributions and Biological Functions Cancers doi: 10.3390/cancers11091247 Authors: Tian Liu Yiwei Wang Yubing Wang Andrew M. Chan Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) is a tumor suppressor gene frequently found to be inactivated in over 30% of human cancers. PTEN encodes a 54-kDa lipid phosphatase that serves as a gatekeeper of the phosphoinositide 3-kinase pathway involved...
Cancers, Vol. 11, Pages 1246: A Multi-Center Study of BRCA1 and BRCA2 Germline Mutations in Mexican-Mestizo Breast Cancer Families Reveals Mutations Unreported in Latin American Population Cancers doi: 10.3390/cancers11091246 Authors: Oliver Millan Catalan Alma D. Campos-Parra Rafael Vázquez-Romo David Cantú de León Nadia Jacobo-Herrera Fermín Morales-González César López-Camarillo Mauricio Rodríguez-Dorantes Eduardo López-Urrutia Carlos Pérez-Plasencia The...
Cancers, Vol. 11, Pages 1244: Review and Comparison of Cancer Biomarker Trends in Urine as a Basis for New Diagnostic Pathways Cancers doi: 10.3390/cancers11091244 Authors: Bax Lotesoriere Sironi Capelli Cancer is one of the major causes of mortality worldwide and its already large burden is projected to increase significantly in the near future with a predicted 22 million new cancer cases and 13 million cancer-related deaths occurring annually by 2030. Unfortunately, current...
Cancers, Vol. 11, Pages 1245: Novel Carbazole-Piperazine Hybrid Small Molecule Induces Apoptosis by Targeting BCL-2 and Inhibits Tumor Progression in Lung Adenocarcinoma in Vitro and Xenograft Mice Model Cancers doi: 10.3390/cancers11091245 Authors: Mongre Mishra Prakash Jung Lee Kumari Hong Lee Lung cancer is a type of deadly cancer and a leading cause of cancer associated death worldwide. BCL-2 protein is considered as an imperative target for the treatment...
Cancers, Vol. 11, Pages 1243: Lactate Dehydrogenase (LDH) Response to First-Line Treatment Predicts Survival in Metastatic Breast Cancer: First Clues for A Cost-Effective and Dynamic Biomarker Cancers doi: 10.3390/cancers11091243 Authors: Giacomo Pelizzari Debora Basile Silvia Zago Camilla Lisanti Michele Bartoletti Lucia Bortot Maria Grazia Vitale Valentina Fanotto Serena Barban Marika Cinausero Marta Bonotto Lorenzo Gerratana Mauro Mansutti Francesco...
Cancers, Vol. 11, Pages 1242: The PI3K/AKT/mTOR and CDK4/6 Pathways in Endocrine Resistant HR+/HER2− Metastatic Breast Cancer: Biological Mechanisms and New Treatments Cancers doi: 10.3390/cancers11091242 Authors: Daniele Presti Erica Quaquarini Endocrine-based treatments are the normal standard-of-care in women with hormone receptor-positive/Human Epidermal growth factor Receptor 2-negative metastatic breast cancer. Despite the well-known efficacy of these drugs as first-line therapies,...
Cancers, Vol. 11, Pages 1240: Role of the Microenvironment in Regulating Normal and Cancer Stem Cell Activity: Implications for Breast Cancer Progression and Therapy Response Cancers doi: 10.3390/cancers11091240 Authors: Vasudeva Bhat Alison L. Allan Afshin Raouf The epithelial cells in an adult woman’s breast tissue are continuously replaced throughout their reproductive life during pregnancy and estrus cycles. Such extensive epithelial cell turnover is governed by the...
Cancers, Vol. 11, Pages 1241: The Diverse Contributions of Fucose Linkages in Cancer Cancers doi: 10.3390/cancers11091241 Authors: Tyler S. Keeley Shengyu Yang Eric Lau Fucosylation is a post-translational modification of glycans, proteins, and lipids that is responsible for many biological processes. Fucose conjugation via α(1,2), α(1,3), α(1,4), α(1,6), and O’- linkages to glycans, and variations in fucosylation linkages, has...
Cancers, Vol. 11, Pages 1238: Enrichment of Aldolase C Correlates with Low Non-Mutated IDH1 Expression and Predicts a Favorable Prognosis in Glioblastomas Cancers doi: 10.3390/cancers11091238 Authors: Chang Tsai Huang Chen Hsiao Tsai The aldolases family is one of the main enzymes involved in the process of glycolysis. Aldolase C (ALDOC), which belongs to the aldolase family, is found in normal brain tissue and is responsible for the repair of injured tissue. However,...
Cancers, Vol. 11, Pages 1237: Risk Assessment of kINPen Plasma Treatment of Four Human Pancreatic Cancer Cell Lines with Respect to Metastasis Cancers doi: 10.3390/cancers11091237 Authors: Sander Bekeschus Eric Freund Chiara Spadola Angela Privat-Maldonado Christine Hackbarth Annemie Bogaerts Anke Schmidt Kristian Wende Klaus-Dieter Weltmann Thomas von Woedtke Claus-Dieter Heidecke Lars-Ivo Partecke André Käding Cold physical plasma has limited tumor...
Cancers, Vol. 11, Pages 1239: Trends in Overall Survival and Treatment Patterns in Two Large Population-Based Cohorts of Patients with Breast and Colorectal Cancer Cancers doi: 10.3390/cancers11091239 Authors: Abbema Vissers Vos-Geelen Lemmens Janssen-Heijnen Tjan-Heijnen Previous studies showed substantial improvement of survival rates in patients with cancer in the last two decades. However, lower survival rates have been reported for older patients compared to...
Cancers, Vol. 11, Pages 1234: Involvement of the Anterior Commissure in Early Glottic Cancer (Tis-T2): A Review of the Literature Cancers doi: 10.3390/cancers11091234 Authors: Martine Hendriksma Elisabeth V. Sjögren Background: The impact of the anterior commissure (AC) involvement on prognosis in laryngeal cancer remains a topic of discussion with inconsistent results in the literature. This review examines AC involvement as a prognostic factor in patients with early glottic cancer...
Cancers, Vol. 11, Pages 1235: Cancer Diagnosis Using Deep Learning: A Bibliographic Review Cancers doi: 10.3390/cancers11091235 Authors: Khushboo Munir Hassan Elahi Afsheen Ayub Fabrizio Frezza Antonello Rizzi In this paper, we first describe the basics of the field of cancer diagnosis, which includes steps of cancer diagnosis followed by the typical classification methods used by doctors, providing a historical idea of cancer classification techniques to the readers. These...
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