Related ArticlesRadiomic analysis of multiparametric magnetic resonance imaging for differentiating skull base chordoma and chondrosarcoma. Eur J Radiol. 2019 Sep;118:81-87 Authors: Li L, Wang K, Ma X, Liu Z, Wang S, Du J, Tian K, Zhou X, Wei W, Sun K, Lin Y, Wu Z, Tian J Abstract PURPOSE: Patients with skull base chordoma and chondrosarcoma have different prognoses and are not readily differentiated preoperatively on imaging. Multiparametric magnetic...
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Related ArticlesRoadmap for a competency-based educational curriculum in epileptology: report of the Epilepsy Education Task Force of the International League Against Epilepsy. Epileptic Disord. 2019 Apr 01;21(2):129-140 Authors: Blümcke I, Arzimanoglou A, Beniczky S, Wiebe S Abstract Teaching competency in the diagnosis and clinical management of epilepsy is of utmost importance for the ILAE. To achieve this mission, the Task Force for Epilepsy Education...
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Related ArticlesCognitive function and neuropathological outcomes: a forward-looking approach. J Neurol. 2019 Aug 21;: Authors: Munoz E, Filshtein T, Bettcher BM, McLaren D, Hedden T, Tommet D, Mungas D, Therneau T Abstract OBJECTIVE: To evaluate the risk of Alzheimer's disease-related neuropathology burden at autopsy given older adults' current cognitive state. METHOD: Participants included 1,303 individuals who enrolled in the Religious Orders...
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Related ArticlesPrognostic and Clinicopathological Correlations of Cell Cycle Marker Expressions before and after the Primary Systemic Therapy of Breast Cancer. Pathol Oncol Res. 2019 Aug 24;: Authors: Tőkés T, Tőkés AM, Szentmártoni G, Kiszner G, Mühl D, Molnár BÁ, Kulka J, Krenács T, Dank M Abstract We aimed to analyze the expression of cell-cycle regulation markers - minichromosome maintenance protein 2 (MCM2), Ki-67, Cyclin-A and phosphohistone-H3...
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Related ArticlesExpression Levels of 4 Genes in Colon Tissue Might be Used to Predict Which Patients Will Enter Endoscopic Remission After Vedolizumab Therapy for Inflammatory Bowel Diseases. Clin Gastroenterol Hepatol. 2019 Aug 22;: Authors: Verstockt B, Verstockt S, Veny M, Dehairs J, Arnauts K, Van Assche G, De Hertogh G, Vermeire S, Salas A, Ferrante M Abstract BACKGROUND & AIMS: We aimed to identify biomarkers that might be used to predict responses...
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Related ArticlesGenomic Landscape and Immune Microenvironment Features of Preinvasive and Early-Invasive Lung Adenocarcinoma. J Thorac Oncol. 2019 Aug 22;: Authors: Zhang C, Zhang J, Xu FP, Wang YG, Xie Z, Su J, Dong S, Nie Q, Shao Y, Zhou Q, Yang JJ, Yang XN, Zhang XC, Li Z, Wu YL, Zhong WZ Abstract BACKGROUND: Understanding the genomic landscape and immune microenvironment features of preinvasive and early-invasive lung adenocarcinoma may provide critical...
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Related ArticlesDesign of an immunohistochemistry biomarker panel for diagnosis of pancreatic adenocarcinoma. Pancreatology. 2019 Aug 13;: Authors: Burnett AS, Quinn PL, Ajibade DV, Peters SR, Ahlawat SK, Mahmoud OM, Chokshi RJ Abstract BACKGROUND: Challenges still exist in differentiating pancreatic adenocarcinoma from benign disease. The use of adjuvant testing of tissue biopsies has demonstrated potential diagnostic value. We designed a proof of concept...
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Related ArticlesCorrelation between maximum standardized uptake values on FDG-PET and microenvironmental factors in patients with clinical stage IA radiologic pure-solid lung adenocarcinoma. Lung Cancer. 2019 Aug 09;136:57-64 Authors: Ichikawa T, Aokage K, Miyoshi T, Tane K, Suzuki K, Makinoshima H, Tsuboi M, Ishii G Abstract OBJECTIVES: The purpose of this study was to investigate whether fluorodeoxyglucose (FDG) accumulation is associated with the...
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Related ArticlesA Novel Next-Generation Sequencing Approach to Detecting Microsatellite Instability (MSI) and Pan-Tumor Characterization of One Thousand MSI-High Cases in 67,000 Patient Samples. J Mol Diagn. 2019 Aug 21;: Authors: Trabucco SE, Gowen K, Maund SL, Sanford E, Fabrizio DA, Hall MJ, Yakirevich E, Gregg JP, Stephens PJ, Frampton GM, Hegde PS, Miller VA, Ross JS, Hartmaier RJ, Huang SA, Sun JX Abstract Microsatellite instability (MSI) is an...
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Related ArticlesMicro-RNA 205-5p is Involved in the Progression of Gastric Cancer and Targets Phosphatase and Tensin Homolog (PTEN) in SGC-7901 Human Gastric Cancer Cells. Med Sci Monit. 2019 Aug 24;25:6367-6377 Authors: Yao L, Shi W, Gu J Abstract BACKGROUND This study aimed to investigate the role of micro-RNA 205-5p (miR-205-5p) in the progression of gastric cancer, and the target of miR-205-5p in human gastric cancer cells in vitro. MATERIAL AND...
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Related ArticlesBAG3 expression correlates with the grade of dysplasia in squamous intraepithelial lesions of the uterine cervix. Acta Obstet Gynecol Scand. 2019 Aug 23;: Authors: Raffone A, Travaglino A, D' Antonio A, De Marco M, Caccese M, Mascolo M, Insabato L, Zeppa P, Rosati A, Mollo A, Zullo F, Guida M Abstract INTRODUCTION: Bcl-2-associated athanogene 3 (BAG3) is a protein involved in apoptosis and stress response, which is overexpressed in invasive...
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Related ArticlesRenal cell tumors with an entrapped papillary component: a collision with predilection for oncocytic tumors. Virchows Arch. 2019 Aug 23;: Authors: Williamson SR, Cheng L, Gadde R, Giannico GA, Wasco MJ, Taylor Smith PJ, Gupta NS, Grignon DJ, Jorda M, Kryvenko ON Abstract Renal cell tumors with mixed morphology resembling multiple renal cell carcinoma (RCC) subtypes are generally regarded as unclassified RCC. However, occasionally, papillary...
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Related ArticlesA co-expressed gene status of adenylate kinase 1/4 reveals prognostic gene signature associated with prognosis and sensitivity to EGFR targeted therapy in lung adenocarcinoma. Sci Rep. 2019 Aug 23;9(1):12329 Authors: Jan YH, Lai TC, Yang CJ, Huang MS, Hsiao M Abstract Cancer cells utilize altered bioenergetics to fuel uncontrolled proliferation and progression. At the core of bioenergetics, adenine nucleotides are the building blocks...
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Related ArticlesGrb2-associated binding protein-1 as a biomarker in bone and soft tissue sarcomas. Pathology. 2019 Aug 20;: Authors: Al-Husseinawi E, Bui MM, Ahmed AA Abstract The Grb2-associated binding proteins are a family of platform proteins involved in signalling transduction pathways. A major family member, Gab1, modulates the effect of growth factor receptors and intracellular signalling pathways, including the phosphatidylinositol 3-kinase and...
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Related ArticlesHigh nuclear NADPH oxidase 4 expression levels are correlated with cancer development and poor prognosis in hepatocellular carcinoma. Pathology. 2019 Aug 20;: Authors: Eun HS, Chun K, Song IS, Oh CH, Seong IO, Yeo MK, Kim KH Abstract NADPH oxidase (NOX) is a key source of reactive oxygen species (ROS). This study aimed to verify NOX2 and NOX4 expression levels in hepatocellular carcinoma (HCC). A total of 134 matched pairs of HCC cells...
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Related ArticlesDoes a polarization state exist for mast cells in cancer? Med Hypotheses. 2019 Oct;131:109281 Authors: Presta I, Donato A, Zaffino P, Spadea MF, Mancuso T, Malara N, Chiefari E, Donato G Abstract The data of literature are discordant about the role of mast cells in different types of neoplasms. In this paper the authors propose the hypothesis that tumor-associated mast cells may switch to different polarization states, conditioning the...
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Related ArticlesPrognostic value of biomarkers EpCAM and αB-crystallin associated with lymphatic metastasis in breast cancer by iTRAQ analysis. BMC Cancer. 2019 Aug 23;19(1):831 Authors: Zeng L, Deng X, Zhong J, Yuan L, Tao X, Zhang S, Zeng Y, He G, Tan P, Tao Y Abstract BACKGROUND: Metastasis is responsible for the majority of deaths in a variety of cancer types, including breast cancer. Although several factors or biomarkers have been identified to...
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Related ArticlesDisulfiram Overcomes Cisplatin Resistance in Human Embryonal Carcinoma Cells. Cancers (Basel). 2019 Aug 22;11(9): Authors: Schmidtova S, Kalavska K, Gercakova K, Cierna Z, Miklikova S, Smolkova B, Buocikova V, Miskovska V, Durinikova E, Burikova M, Chovanec M, Matuskova M, Mego M, Kucerova L Abstract Cisplatin resistance in testicular germ cell tumors (TGCTs) is a clinical challenge. We investigated the underlying mechanisms associated...
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Related ArticlesImproved Survival in Hepatocellular Carcinoma Patients with Cardiac Arrhythmia by Amiodarone Treatment through Autophagy. Int J Mol Sci. 2019 Aug 15;20(16): Authors: Huang ST, Hsu WF, Huang HS, Yen JH, Lin MC, Peng CY, Yen HR Abstract Hepatocellular carcinoma (HCC) is a primary malignancy of the liver. In basic studies, the regulation of autophagy has offered promising results for HCC treatment. This study aimed to address the question...
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326 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: cancer immunohistochemistry These pubmed results were generated on 2019/08/24PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Related ArticlesImmunoglobulin treatment for hospitalised infants and young children with respiratory syncytial virus infection. Cochrane Database Syst Rev. 2019 Aug 26;8:CD009417 Authors: Sanders SL, Agwan S, Hassan M, van Driel ML, Del Mar CB Abstract BACKGROUND: Millions of children are hospitalised due to respiratory syncytial virus (RSV) infection every year. Treatment is supportive, and current therapies (e.g. inhaled bronchodilators, epinephrine,...
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Related ArticlesAcupuncture for chronic hepatitis B. Cochrane Database Syst Rev. 2019 Aug 22;8:CD013107 Authors: Kong Z, Liang N, Yang GL, Zhang Z, Liu Y, Yang Y, Liu YX, Wang QG, Zhang F, Zhang HY, Nikolova D, Jakobsen JC, Gluud C, Liu JP Abstract BACKGROUND: Chronic hepatitis B is a liver disease associated with high morbidity and mortality. Chronic hepatitis B requires long-term management aiming to reduce the risks of hepatocellular inflammatory...
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Related ArticlesTo eat is to practice-managing eating problems after head and neck cancer. J Cancer Surviv. 2019 Aug 24;: Authors: Kristensen MB, Mikkelsen TB, Beck AM, Zwisler AD, Wessel I, Dieperink KB Abstract PURPOSE: The purpose of this qualitative study was twofold: (1) to explore head and neck cancer (HNC) survivors' experiences of everyday life with eating problems after cancer treatment and (2) to explore their experiences of participating in...
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Related ArticlesCardiovascular Effects of Androgen Deprivation Therapy in Prostate Cancer. Curr Oncol Rep. 2019 Aug 24;21(10):91 Authors: Agarwal M, Canan T, Glover G, Thareja N, Akhondi A, Rosenberg J Abstract PURPOSE OF THE REVIEW: This review paper is a comprehensive look at the cardiovascular disease (CVD) risk that is associated with the use of androgen deprivation therapy in prostate cancer. It summarizes when certain cancer therapies are indicated...
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Related ArticlesPilot Study of Bortezomib and Dexamethasone Pre- and Post-Risk-Adapted Autologous Stem Cell Transplantation in AL Amyloidosis. Biol Blood Marrow Transplant. 2019 Aug 22;: Authors: Landau H, Lahoud O, Devlin S, Lendvai N, Chung DJ, Dogan A, Landgren CO, Giralt S, Hassoun H Abstract Treatment for AL amyloidosis aims to eradicate clonal plasma cells, thereby disrupting the amyloid deposition causing organ damage. Risk-adapted high-dose melphalan...
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Related ArticlesCommercial Insurance Coverage of Advanced Radiotherapy Techniques Compared to American Society for Radiation Oncology Model Policies. Pract Radiat Oncol. 2019 Aug 22;: Authors: Verma V, Ludmir EB, Mesko SM, Brooks ED, Augustyn A, Milano MT, Lin SH, Chang JY, Welsh JW Abstract BACKGROUND: To compare and contrast the American Society for Radiation Oncology (ASTRO) Model Policies (MPs) for intensity-modulated radiation therapy (IMRT), stereotactic...
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Related ArticlesCurrent Methods of Maxillofacial Tissue Engineering. Oral Maxillofac Surg Clin North Am. 2019 Aug 21;: Authors: Melville JC, Mañón VA, Blackburn C, Young S Abstract For several decades, the multidisciplinary field of tissue engineering has striven to improve conventional methods of dental, oral, and craniofacial rehabilitation for millions of people annually. Several bone tissue engineering strategies are now readily available in the...
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Related ArticlesGastric cancer: Translating novels concepts into clinical practice. Cancer Treat Rev. 2019 Aug 14;79:101889 Authors: Salati M, Orsi G, Smyth E, Beretta G, De Vita F, Di Bartolomeo M, Fanotto V, Lonardi S, Morano F, Pietrantonio F, Pinto C, Rimassa L, Vasile E, Vivaldi C, Zaniboni A, Ziranu P, Cascinu S Abstract The overall 5-year survival of gastric cancer (GC) has change only little in the last decades and it remains the fifth leading...
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Related ArticlesThe adjuvant treatment revolution for high-risk melanoma patients. Semin Cancer Biol. 2019 Aug 21;: Authors: Spagnolo F, Boutros A, Tanda E, Queirolo P Abstract The past 5 years have witnessed the results of many practice-changing studies that have dramatically improved the landscape of adjuvant therapy in patients with resected, high-risk melanoma. After a 20-year era of adjuvant interferon, the anti-CTLA-4 and anti-PD-1 immune-checkpoint...
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Related ArticlesThe Dichotomous Role of the Glycolytic Metabolism Pathway in Cancer Metastasis: Interplay with the Complex Tumor Microenvironment and Novel Therapeutic Strategies. Semin Cancer Biol. 2019 Aug 21;: Authors: El Hassouni B, Granchi C, Vallés-Martí A, Supadmanaba IGP, Bononi G, Tuccinardi T, Funel N, Jimenez CR, Peters GJ, Giovannetti E, Minutolo F Abstract Cancer metastasis to distant organs is initiated by tumor cells that disseminate from...
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Related ArticlesUmbrella and basket trials in oncology: ethical challenges. BMC Med Ethics. 2019 Aug 23;20(1):58 Authors: Strzebonska K, Waligora M Abstract BACKGROUND: Novel precision oncology trial designs, such as basket and umbrella trials, are designed to test new anticancer agents in more effective and affordable ways. However, they present some ethical concerns referred to scientific validity, risk-benefit balance and informed consent. Our aim...
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Related ArticlesNeoantigen vaccine: an emerging tumor immunotherapy. Mol Cancer. 2019 Aug 23;18(1):128 Authors: Peng M, Mo Y, Wang Y, Wu P, Zhang Y, Xiong F, Guo C, Wu X, Li Y, Li X, Li G, Xiong W, Zeng Z Abstract Genetic instability of tumor cells often leads to the occurrence of a large number of mutations, and expression of non-synonymous mutations can produce tumor-specific antigens called neoantigens. Neoantigens are highly immunogenic as they are...
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