Authors: Roviello G, Nobili S, Mini E PMID: 31432747 [PubMed - as supplied by publisher] (Source: Journal of Chemotherapy)MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm running.
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Hello, fellow Pythonistas! I have been creating some notebooks for a Python beginner sessions series that I'm conducting at my company. I wanted to share these with the community here as well for a two-fold purpose. For the benefit of any other fellow learners out there who might find these useful. To get a feedback from the community both on the quality of the content, and the content covered. Here is the link for the notebooks on Github (there will be a few more added soon): https://www.github.com/sethips/python_basic_lessons...
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I need to present complaints per 100 residents using the NYC OpenData - 311 Service Requests dataset Below is a head of the data Created Date Complaint Type Descriptor Location Type Incident Zip Street Name Cross Street 1 Cross Street 2 City Status Community Board Borough 0 2010-01-01 00:00:00 HEATING HEAT RESIDENTIAL BUILDING 10468 RESERVOIR AVENUE WEST 195 STREET GOULDEN AVENUE BRONX Open 08 BRONX BRONX 1 2010-01-01 00:00:00 GENERAL CONSTRUCTION DOORS RESIDENTIAL BUILDING 10468 RESERVOIR AVENUE...
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CONCLUSIONS: The preliminary results of the present phase II trial, using HT for moderate hypofractionation in localized prostate cancer, are optimal. In fact, HT guaranteed an acceptable tolerability profile with low rates of GU and GI side effects and, more specifically, no acute severe adverse events were recorded. Long-term findings are warranted. PMID: 31432765 [PubMed - as supplied by publisher] (Source: Tumori)
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Related ArticlesThe N-terminal peptide of the transglutaminase-activating metalloprotease inhibitor from Streptomyces mobaraensis accommodates both inhibition and glutamine cross-linking sites. FEBS J. 2019 Aug 17;: Authors: Juettner NE, Schmelz S, Anderl A, Colin F, Classen M, Pfeifer F, Scrima A, Fuchsbauer HL Abstract Streptomyces mobaraensis is a key player for the industrial production of the protein cross-linking enzyme microbial transglutaminase...
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Related ArticlesBiochemical and biophysical comparison of human and mouse beta-2 microglobulin reveals the molecular determinants of low amyloid propensity. FEBS J. 2019 Aug 17;: Authors: Achour A, Broggini L, Han X, Sun R, Santambrogio C, Buratto J, Visentin C, Barbiroli A, De Luca CMG, Sormanni P, Moda F, De Simone A, Sandalova T, Grandori R, Camilloni C, Ricagno S Abstract The molecular bases of amyloid aggregation propensity are still poorly understood,...
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Related ArticlesA guide to Mycobacterium mutagenesis. FEBS J. 2019 Aug 16;: Authors: Borgers K, Vandewalle K, Festjens N, Callewaert N Abstract The genus Mycobacterium includes several pathogens that cause severe disease in humans, like Mycobacterium tuberculosis (M. tb), the infectious agent causing tuberculosis. Genetic tools to engineer mycobacterial genomes, in a targeted or random fashion, have provided opportunities to investigate M. tb infection...
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Related ArticlesKettin, the large actin-binding protein with multiple immunoglobulin domains, is essential for sarcomeric actin assembly and larval development in Caenorhabditis elegans. FEBS J. 2019 Aug 14;: Authors: Ono K, Qin Z, Johnsen RC, Baillie DL, Ono S Abstract Among many essential genes in the nematode Caenorhabditis elegans, let-330 is located on the left arm of chromosome V and was identified as the largest target of a mutagen in this region....
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Related ArticlesMROH7-TTC4 read-through lncRNA suppresses vascular endothelial cell apoptosis and is upregulated by inhibition of ANXA7 GTPase activity. FEBS J. 2019 Aug 13;: Authors: He X, Zhao X, Su L, Zhao B, Miao J Abstract Apoptosis of vascular endothelial cells (VEC) is the main form of vascular injury that is closely linked to numerous cardiovascular diseases. Therefore, it is important to find new factors that can suppress VEC apoptosis. By...
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Related ArticlesProteolytic and Nonproteolytic Activation Mechanisms Result in Conformationally and Functionally Different Forms of Coagulation Factor XIII A. FEBS J. 2019 Aug 13;: Authors: Anokhin BA, Dean WL, Smith KA, Flick MJ, Ariëns RAS, Philippou H, Maurer MC Abstract Factor XIIIA (FXIIIA) is a transglutaminase that crosslinks intra- and extracellular protein substrates. FXIIIA is expressed as an inactive zymogen, and during blood coagulation,...
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Related ArticlesNew oncogenic signalling pathway: EWS-Oct4 mediates bone and soft tissue tumourigenesis by activating fibroblast growth factor-4. FEBS J. 2019 Aug 09;: Authors: Chen D, Lee TH Abstract Chromosomal translocations involving the interchange of parts between two nonhomologous chromosomes can often lead to cancer by creating new fusion proteins. Here, Kim and co-workers show that a chimeric protein, Ewing's sarcoma-octamer-binding transcription...
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Related ArticlesA new mechanism for translational control in plants. FEBS J. 2019 Aug 09;: Authors: Miller WA, Dinesh-Kumar SP Abstract In unstressed conditions, the cap-binding protein, eIF4E, binds the 5' cap structure (m7G) on mRNA and recruits other translation initiation factors to bring the ribosome to the mRNA. Bruns et al. show that, in plants, phosphorylation of eIF4E by the master metabolic regulatory protein, sucrose nonfermenting-related...
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Atmosphere, Vol. 10, Pages 492: Characterising Particulate Organic Nitrogen at A Savannah-Grassland Region in South Africa Atmosphere doi: 10.3390/atmos10090492 Authors: Wanda Booyens Pieter G. Van Zyl Johan P. Beukes Jose Ruiz-Jimenez Matias Kopperi Marja-Liisa Riekkola Ville Vakkari Miroslav Josipovic Markku Kulmala Lauri Laakso Although atmospheric organic N compounds are considered to be important, especially in new particle formation and their contribution...
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Atmosphere, Vol. 10, Pages 490: Spatial Predictability of Heavy Rainfall Events in East China and the Application of Spatial-Based Methods of Probabilistic Forecasting Atmosphere doi: 10.3390/atmos10090490 Authors: Xiaoran Zhuang Haonan Zhu Jinzhong Min Liu Zhang Naigen Wu Zhipeng Wu Shiqi Wang One of the major issues in developing convective-scale ensemble forecasts is what is widely known as under-dispersion. This can be addressed through the consideration of spatial...
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Atmosphere, Vol. 10, Pages 489: Water Pathways for the Hindu-Kush-Himalaya and an Analysis of Three Flood Events Atmosphere doi: 10.3390/atmos10090489 Authors: Robert Boschi Valerio Lucarini The climatology of major sources and pathways of moisture for three locales along the Hindu-Kush-Himalayan region are examined, by use of Lagrangian methods applied to the ERA-Interim dataset, over the period from 1980 to 2016 for both summer (JJA) and winter (NDJ) periods. We also investigate...
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Atmosphere, Vol. 10, Pages 488: VAPOR: A Visualization Package Tailored to Analyze Simulation Data in Earth System Science Atmosphere doi: 10.3390/atmos10090488 Authors: Shaomeng Li Stanislaw Jaroszynski Scott Pearse Leigh Orf John Clyne Visualization is an essential tool for analysis of data and communication of findings in the sciences, and the Earth System Sciences (ESS) are no exception. However, within ESS, specialized visualization requirements and data models, particularly...
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Atmosphere, Vol. 10, Pages 487: Measuring Regional Atmospheric CO2 Concentrations in the Lower Troposphere with a Non-Dispersive Infrared Analyzer Mounted on a UAV, Ogata Village, Akita, Japan Atmosphere doi: 10.3390/atmos10090487 Authors: Takashi Chiba Yumi Haga Makoto Inoue Osamu Kiguchi Takeshi Nagayoshi Hirokazu Madokoro Isamu Morino We have developed a simple measuring system prototype that uses an unmanned aerial vehicle (UAV) and a non-dispersive infrared (NDIR)...
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Related ArticlesNeuropathologic basis of in vivo cortical atrophy in the aphasic variant of alzheimer's disease. Brain Pathol. 2019 Aug 25;: Authors: Ohm DT, Fought AJ, Rademaker A, Kim G, Sridhar J, Coventry C, Gefen T, Weintraub S, Bigio E, Mesulam MM, Rogalski E, Geula C Abstract The neuropathologic basis of in vivo cortical atrophy in clinical dementia syndromes remains poorly understood. This includes primary progressive aphasia (PPA), a language-based...
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Related ArticlesNeuropathology of dementia in patients with Parkinson's disease: a systematic review of autopsy studies. J Neurol Neurosurg Psychiatry. 2019 Aug 23;: Authors: Smith C, Malek N, Grosset K, Cullen B, Gentleman S, Grosset DG Abstract BACKGROUND: Dementia is a common, debilitating feature of late Parkinson's disease (PD). PD dementia (PDD) is associated with α-synuclein propagation, but coexistent Alzheimer's disease (AD) pathology may coexist....
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Related ArticlesIdentification of prognostic factors to predict cognitive decline of patients with early Alzheimer's disease in the Japanese Alzheimer's Disease Neuroimaging Initiative study. Alzheimers Dement (N Y). 2019;5:364-373 Authors: Yagi T, Kanekiyo M, Ito J, Ihara R, Suzuki K, Iwata A, Iwatsubo T, Aoshima K, Alzheimer's Disease Neuroimaging Initiative, Japanese Alzheimer's Disease Neuroimaging Initiative Abstract Introduction: The objective...
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