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Τετάρτη 7 Αυγούστου 2019

Daily step counts: A new prognostic factor in locally advanced non-small cell lung cancer?
Publication date: Available online 7 August 2019Source: International Journal of Radiation Oncology*Biology*PhysicsAuthor(s): Nitin Ohri, Balazs Halmos, William R. Bodner, Haiying Cheng, Chandan Guha, Shalom Kalnicki, Madhur GargABSTRACTIntroductionHere we explore the prognostic value of baseline step count data captured using wearable devices for patients treated with definitive chemoradiotherapy for locally advanced non-small cell lung cancer (NSCLC).MethodsLocally advanced NSCLC patients wore...
Radiation Molecular Biology.
17h
Development of genomic simple sequence repeat markers for Glycyrrhiza lepidota and cross-amplification of other Glycyrrhiza species
Background Licorice (Glycyrrhiza spp. L.) is used as a natural sweetener and medicinal herb in European and Asian countries. Molecular studies have been conducted to find differences between wild and cultivated species because most wild species are highly resistant to abiotic and biotic stresses compared with their cultivated species. However, few molecular markers have been developed for studying the genetic diversity and population structure of licorice species and to identify...
PeerJ Computer Science
21h
Gaining insights in the nutritional metabolism of amphibians: analyzing body nutrient profiles of the African clawed frog, Xenopus laevis
Whole bodies of Xenopus laevis (n = 19) were analysed for chemical composition and morphometrics. The nutrient profile (macronutrients, amino acids, fatty acids and minerals) was evaluated by sex; interactions among variables with body weights and lengths, and comparisons made with different species of marine and fresh water fish. Significant differences were found in morphometric measurements, water content, several minerals and fatty acids between sexes of X. laevis. Amino acid profiles differed...
PeerJ Computer Science
21h
Validity of the iLOAD® app for resistance training monitoring
Background This study aimed (I) to assess the inter-rater agreement for measuring the mean velocity (MV) of the barbell with the iLOAD® app, and (II) to compare the magnitude of the MV and total work of a training session between the iLOAD® app and a linear encoder (reference method). Method Sixteen young healthy individuals (four women and 12 men) were tested in two sessions separated by 48 h. The 10 repetition maximum...
PeerJ Computer Science
21h
Patient-reported outcomes measured with and without dizziness associated with non-specific chronic neck pain: implications for primary care
Background The aim of this study was to compare health-related quality of life (HRQoL) and disability and fear of movement in patients with non-specific chronic neck pain (NSCNP) associated with dizziness with respect to patients with isolated NSCNP in primary care settings. Methods A cross-sectional study was carried out in a primary care center. A total of 120 patients were divided into two groups and analyzed in this study....
PeerJ Computer Science
21h
The clinical value of carcinoembryonic antigen for tumor metastasis assessment in lung cancer
Background Carcinoembryonic antigen (CEA) as a diagnostic or prognostic marker has been widely studied in patients with lung cancer. However, the relationship between serum CEA and tumor metastasis in lung cancer remains controversial. This study aimed to investigate the ability of serum CEA to assess tumor metastasis in lung cancer patients. Methods We performed a retrospective analysis of 238 patients diagnosed with...
PeerJ Computer Science
21h
Muscle quality index and isometric strength in older adults with hip osteoarthritis
Background Older adults with hip osteoarthritis (OA) suffer a progressive loss of muscle quality and strength, affecting their daily activities and quality of life. The purpose of this study is to compare the levels of isometric strength among older adults with and without hip OA and healthy young adults, and to determine the relationship between muscle quality index (MQI) and isometric strength. Methods Fourteen subjects...
PeerJ Computer Science
21h
Acute net stress of young adult zebrafish (Danio rerio) is not sufficient to increase anxiety-like behavior and whole-body cortisol
In recent years, the zebrafish (Danio rerio) has become a popular model to study the mechanisms of physiological and behavioral effects of stress, due to the similarity in neural structures and biochemical pathways between zebrafish and mammals. Previous research in this vertebrate animal model has demonstrated an increase in whole-body cortisol resulting from an acute (30-second) net handling stress, but it remains unclear whether such a stressor will concomitantly increase anxiety-like behavior....
PeerJ Computer Science
21h
Analysis of Expression and Single Nucleotide Polymorphisms of INHA Gene Associated with Reproductive Traits in Chickens
Inhibin α (INHA) is a candidate gene controlling ovulation in poultry. As the functional center of inhibin, INHA is a molecular marker associated with egg-laying performance. The objective of the current study was to analyze the expression differences of INHA in reproductive system and single nucleotide polymorphisms (SNPs) associations with reproductive traits in chickens. A total of 260 LuHua chickens (barred-feather chicken) were adopted. Twelve SNPs were detected in INHA gene. Among the exonic...
BioMed Research International
4h
Aortic Arch Calcification Is a Strong Predictor of the Severity of Coronary Artery Disease in Patients with Acute Coronary Syndrome
Background. The purpose of this study was to investigate the correlation of the extent of aortic arch calcification (AAC) detectable on chest X-rays with the severity of coronary artery disease (CAD) as evaluated by the SYNTAX score (SS) in patients with acute coronary syndrome (ACS). Methods. A total of 1,418 patients (344 women; 59 ± 10 years) who underwent coronary angiography for ACS and were treated with coronary revascularization were included in the present study; chest X-rays were performed...
BioMed Research International
18h
Different Mechanistic Association of Myopia with Rhegmatogenous Retinal Detachment between Young and Elderly Patients
Objectives. To investigate the mechanism of rhegmatogenous retinal detachment (RRD) in young and elderly Korean patients based on the results of axial length distribution. Subjects/Methods. We retrospectively reviewed the medical records of 1599 patients with RRD who had bilateral axial length data examined at one center between 2003 and 2018. Axial lengths were measured using ultrasound or IOLMaster500. The frequency of RRD and axial length distribution according to age groups were investigated....
BioMed Research International
20h
Identification of Potential Biomarkers and Survival Analysis for Head and Neck Squamous Cell Carcinoma Using Bioinformatics Strategy: A Study Based on TCGA and GEO Datasets
The mechanism and gene markers of head and neck squamous cell carcinoma (HNSCC), a common malignant tumor, have not yet been identified. The aim of this study was to identify the key genes and pathways associated with HNSCC and to further analyze its molecular mechanism and prognostic significance. In this study, the expression profile chip data GSE6631 from Gene Expression Omnibus (GEO) included paired HNSCC tumor and normal samples from 22 patients; the RNAseq tertiary dataset of HNSCC and corresponding...
BioMed Research International
21h

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