MONDAY, Aug. 26, 2019 -- The treatments that childhood cancer patients receive often save their lives, but they also make survivors prone to heart troubles, a new study finds. For the study, researchers examined heart disease rates in nearly 7,300... (Source: Drugs.com - Daily MedNews)
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Background: Microbial culture is the gold standard for determining the effectiveness of tuberculosis treatment. End-of-treatment (EOT) FDG-PET/CT findings are variable among patients with negative microbial culture after completing standard regimen of anti-tuberculous treatment (ATT) with some patients having a complete metabolic response to treatment while others have residual metabolic activity (RMA). We herein determine the impact of findings on EOT FDG-PET/CT on tuberculosis relapse in patients...
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The objective of this nationwide survey was to evaluate whether there has been a change in the practice regarding hospital release of differentiated thyroid cancer patients treated with 131I since the publication of Nuclear Regulatory Commission Regulatory Issue Summary 2011-01 addressing patient release. Methods: A survey was emailed to ~25,000 members of ThyCa: Thyroid Cancer Survivors’ Association, Inc. and was available online from March-August 2018. Responses were included from adult patients...
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Rationale: Cardiac allograft vasculopathy (CAV) is a major cause of graft failure after cardiac transplantation. CAV is characterized by diffuse involvement of epicardial coronary arteries and the microvasculature. Positron emission tomography (PET) allows quantification of absolute myocardial blood flow (MBF) and myocardial flow reserve (MFR), which may be accurate markers of CAV severity. We compared the diagnostic and prognostic utility of stress MBF and MFR following cardiac transplantation....
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Purpose: Bone metastases in prostate cancer (PCa) have important prognostic significance and imaging modalities used for PCa staging should have high sensitivity for detecting such lesions. Prostate-specific membrane antigen (PSMA)-targeted positron emission tomography (PET) radiotracers are promising new agents for imaging PCa. We undertook a head-to-head comparison of PSMA-targeted 18F-DCFPyL PET to Na18F PET to determine which modality was more sensitive for the detection of lesions suspicious...
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Background. Pueraria lobata is used in traditional Asian medicine to treat cardiovascular diseases, diarrhea, diabetes mellitus, and diabetic complications such as diabetic retinopathy. Oxidative stress in retinal pigment epithelial cells is implicated in the pathogenesis of retinopathy and age-related macular degeneration (AMD). Here, we evaluated whether the P. lobata extract can prevent cell death and decrease membrane permeability in oxidative stress-induced human retinal pigment epithelial cells....
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Contemporary Topics in Radiation Medicine, Part I: Current Issues and Techniques
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Related ArticlesTRPM7 mediates kidney injury, endothelial hyperpermeability and mortality during endotoxemia. Lab Invest. 2019 Aug 23;: Authors: Gatica S, Villegas V, Vallejos A, Olivares P, Aballai V, Lagos-Meza F, Echeverria C, Cabello-Verrugio C, Varela D, Simon F Abstract Sepsis is the main cause of mortality in patients admitted to intensive care units. During sepsis, endothelial permeability is severely augmented, contributing to renal dysfunction...
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Related ArticlesBlockade of MDM2 with inactive Cas9 prevents epithelial to mesenchymal transition in retinal pigment epithelial cells. Lab Invest. 2019 Aug 22;: Authors: Liu B, Song J, Han H, Hu Z, Chen N, Cui J, Matsubara JA, Zhong J, Lei H Abstract Epithelial to mesenchymal transition (EMT) plays an important role in the pathogenesis of proliferative vitreoretinopathy (PVR). We aimed to demonstrate the role of mouse double minute 2 (MDM2) in transforming...
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Related ArticlesCorrection: Micheliolide ameliorates renal fibrosis by suppressing the Mtdh/BMP/MAPK pathway. Lab Invest. 2019 Aug 16;: Authors: Peng F, Li H, Li S, Wang Y, Liu W, Gong W, Yin B, Chen S, Zhang Y, Luo C, Zhou W, Chen Y, Li P, Huang Q, Xu Z, Long H Abstract An amendment to this paper has been published and can be accessed via a link at the top of the paper.PMID: 31420584 [PubMed - as supplied by publisher]
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Related ArticlesTRPV4 is dispensable for the development of airway allergic asthma. Lab Invest. 2019 Aug 15;: Authors: Palaniyandi S, Rajendrakumar AM, Periasamy S, Goswami R, Tuo W, Zhu X, Rahaman SO Abstract Allergic asthma is one of the most common immune-mediated disorders affecting the lungs. It is characterized clinically by airway hyperresponsiveness, eosinophilia, enhanced IL-4 and IL-13, peribronchial inflammation with mononuclear cell infiltration,...
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Related ArticlesSelective Ah receptor modulators attenuate NPC1L1-mediated cholesterol uptake through repression of SREBP-2 transcriptional activity. Lab Invest. 2019 Aug 15;: Authors: Muku GE, Kusnadi A, Kuzu G, Tanos R, Murray IA, Gowda K, Amin S, Perdew GH Abstract The ability of the aryl hydrocarbon receptor (AHR) to alter hepatic expression of cholesterol synthesis genes in a DRE-independent manner in mice and humans has been reported. We have...
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Related ArticlesLipid droplet velocity is a microenvironmental sensor of aggressive tumors regulated by V-ATPase and PEDF. Lab Invest. 2019 Aug 13;: Authors: Nardi F, Fitchev P, Brooks KM, Franco OE, Cheng K, Hayward SW, Welte MA, Crawford SE Abstract Lipid droplets (LDs) utilize microtubules (MTs) to participate in intracellular trafficking of cargo proteins. Cancer cells accumulate LDs and acidify their tumor microenvironment (TME) by increasing the...
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Related ArticlesDevelopment of a simple osteoarthritis model useful to predict in vitro the anti-hypertrophic action of drugs. Lab Invest. 2019 Aug 13;: Authors: Allas L, Rochoux Q, Leclercq S, Boumédiene K, Baugé C Abstract Osteoarthritis (OA) is characterized by cartilage degradation, inflammation, and hypertrophy. Therapies are mainly symptomatic and aim to manage pain. Consequently, medical community is waiting for new treatments able to reduce...
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Related ArticlesSnoN residue (1-366) attenuates hypertrophic scars through resistance to transforming growth factor-β1-induced degradation. Lab Invest. 2019 Aug 13;: Authors: Sun GF, Li HC, Zhan YP, Zhang XF, Pan LY, Chen YF, Xu K, Feng DX Abstract Hypertrophic scars (HSs) are characterized by fibroblast hyperproliferation and excessive matrix deposition. During wound healing, transforming growth factor (TGF)-β1/Smad signaling acts as a key regulator....
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Related ArticlesRetinoid-related orphan nuclear receptor alpha (RORα)-deficient mice display morphological testicular defects. Lab Invest. 2019 Aug 13;: Authors: Sayed RKA, Mokhtar DM, Fernández-Ortiz M, Escames G, Acuña-Castroviejo D Abstract The role of retinoid-related orphan receptor, one of the transcription factors reported in testis, in testicular function is unclear, so this study was performed to evaluate the qualitative and quantitative changes...
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Related ArticlesMouse pancreatic ductal organoid culture as a relevant model to study exocrine pancreatic ion secretion. Lab Invest. 2019 Aug 13;: Authors: Molnár R, Madácsy T, Varga Á, Németh M, Katona X, Görög M, Molnár B, Fanczal J, Rakonczay Z, Hegyi P, Pallagi P, Maléth J Abstract Pancreatic exocrine secretory processes are challenging to investigate on primary epithelial cells. Pancreatic organoid cultures may help to overcome shortcomings of...
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Related ArticlesMurine neuroblastoma cell lines developed by conditional reprogramming preserve heterogeneous phenotypes observed in vivo. Lab Invest. 2019 Aug 13;: Authors: Krawczyk E, Hong SH, Galli S, Trinh E, Wietlisbach L, Misiukiewicz SF, Tilan JU, Chen YS, Schlegel R, Kitlinska J Abstract Neuroblastoma (NB) is a pediatric tumor of the peripheral nervous system. Treatment of the disease represents an unsolved clinical problem, as survival of patients...
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Related ArticlesInhibiting the Notch signaling pathway suppresses Th17-associated airway hyperresponsiveness in obese asthmatic mice. Lab Invest. 2019 Aug 13;: Authors: Zeng Z, Wang L, Ma W, Zheng R, Zhang H, Zeng X, Zhang H, Zhang W Abstract Notch signaling is crucial for the regulation of asthma and obesity. The interleukin (IL)-17-expressing CD4+ T cell (Th17 cell) response and airway hyperresponsiveness (AHR) are critical features of both asthma...
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Related ArticlesNSG mice as hosts for oncological precision medicine. Lab Invest. 2019 Aug 13;: Authors: Maletzki C, Bock S, Fruh P, Macius K, Witt A, Prall F, Linnebacher M Abstract Patient-derived xenograft (PDX) models have been rediscovered as meaningful research tool. By using severely immunodeficient mice, high-engraftment rates can be theoretically achieved, permitting clinical stratification strategies. Apart from engraftment efficacy, tolerability...
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Related ArticlesQuantitative assessment of PD-L1 as an analyte in immunohistochemistry diagnostic assays using a standardized cell line tissue microarray. Lab Invest. 2019 Aug 13;: Authors: Martinez-Morilla S, McGuire J, Gaule P, Moore L, Acs B, Cougot D, Gown AM, Yaziji H, Wang WL, Cartun RW, Hornick JL, Sholl LM, Qiu J, Mino-Kenudson M, Yi ES, Beasley MB, Merrick DT, Ambaye AB, Zhang ZJ, Walker J, Rimm DL Abstract Programmed death 1 ligand 1 (PD-L1)...
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Related ArticlesMuc5ac null mice are predisposed to spontaneous gastric antro-pyloric hyperplasia and adenomas coupled with attenuated H. pylori-induced corpus mucous metaplasia. Lab Invest. 2019 Aug 09;: Authors: Muthupalani S, Ge Z, Joy J, Feng Y, Dobey C, Cho HY, Langenbach R, Wang TC, Hagen SJ, Fox JG Abstract Gastric cancer (GC) is the third leading cause of cancer-related deaths worldwide and is strongly associated with chronic Helicobacter pylori...
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Related ArticlesSpace-like 56Fe irradiation manifests mild, early sex-specific behavioral and neuropathological changes in wildtype and Alzheimer's-like transgenic mice. Sci Rep. 2019 Aug 20;9(1):12118 Authors: Liu B, Hinshaw RG, Le KX, Park MA, Wang S, Belanger AP, Dubey S, Frost JL, Shi Q, Holton P, Trojanczyk L, Reiser V, Jones PA, Trigg W, Di Carli MF, Lorello P, Caldarone BJ, Williams JP, O'Banion MK, Lemere CA Abstract Space travel will expose...
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18 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi"[jour] These pubmed results were generated on 2019/08/26PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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68 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "MMW Fortschr Med"[jour] These pubmed results were generated on 2019/08/26PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Related ArticlesReconstruction of mandibular defects using vascularized fibular osteomyocutaneous flap combined with nonvascularized fibular flap. Med Oral Patol Oral Cir Bucal. 2019 Aug 19;: Authors: Wang W, Zhu J, Xu B, Xia B, Liu Y, Shao S Abstract BACKGROUND: The height of single-layer fibular flap is not long enough to return to the ideal height of the mandible. While the double-layer vascularized fibular osteomyocutaneous flap(VFF) is more complicated...
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Related ArticlesAssessment of the capacity of a pyrophosphate-based mouth rinse to inhibit the formation of supragingival dental calculus. a randomized double-blind placebo-controlled clinical trial. Med Oral Patol Oral Cir Bucal. 2019 Aug 19;: Authors: Fons-Badal C, Agustín-Panadero R, Solá-Ruíz MF, Alpiste-Illueca F, Font-Fons A Abstract BACKGROUND: This study aimed to analyze the efficacy of an anti-calculus mouth rinse and its possible adverse effects...
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Related ArticlesValidation of microRNA expression profile in Oral Lichenoid Disease through cytological samples. Med Oral Patol Oral Cir Bucal. 2019 Aug 19;: Authors: Setién-Olarra A, Marichalar-Mendia X, Fernández-Pacheco JA, Fernández-Barriales-López M, Gainza-Cirauqui ML, Aguirre-Urizar JM Abstract BACKGROUND: To validate oral exfoliative cytology in the analysis of the microRNA expression profile in Oral Lichenoid Disease (OLD). MATERIAL...
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Related ArticlesOral and dental health status in patients with eating disorders in Madrid, Spain. Med Oral Patol Oral Cir Bucal. 2019 Aug 19;: Authors: Garrido-Martínez P, Domínguez-Gordillo A, Cerero-Lapiedra R, Burgueño-García M, Martínez-Ramírez MJ, Gómez-Candela C, Cebrián-Carretero JL, Esparza-Gómez G Abstract BACKGROUND: The aim of the present study was to describe and compare the oral and dental health status of two groups, one diagnosed with...
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Related ArticlesThe accuracy of three-dimensional rapid prototyped surgical template guided anterior segmental osteotomy. Med Oral Patol Oral Cir Bucal. 2019 Aug 19;: Authors: Qu M, Zhu S, Hu Z, Li Y, Abotaleb B, Bi R, Jiang N Abstract BACKGROUND: Surgical guiding templates provided a reliable way to transfer the simulation to the actual operation. However, there was no template designed for anterior segmental osteotomy so far. The study aimed to introduce...
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Related ArticlesEpigenetics and periodontics: A systematic review. Med Oral Patol Oral Cir Bucal. 2019 Aug 19;: Authors: Almiñana-Pastor PJ, Boronat-Catalá M, Micó-Martinez P, Bellot-Arcís C, Lopez-Rolda A, Alpiste-Illueca FM Abstract BACKGROUND: Despite decades of research, our knowledge of several important aspects of periodontal pathogenesis remains incomplete. Epigenetics allows to perform dynamic analysis of different variations in gene expression,...
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Related ArticlesImpact of crestal and subcrestal implant placement upon changes in marginal peri-implant bone level. A systematic review. Med Oral Patol Oral Cir Bucal. 2019 Aug 19;: Authors: Pellicer-Chover H, Díaz-Sanchez M, Soto-Peñaloza D, Peñarrocha-Diago MA, Canullo L, Peñarrocha-Oltra D Abstract BACKGROUND: To systematically assess studies analyzing peri-implant bone loss in implants placed in crestal and subcrestal position. MATERIAL...
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Related ArticlesTrends of maxillofacial trauma: An update from the prospective register of a multicenter study in emergency services of Chile. Med Oral Patol Oral Cir Bucal. 2019 Aug 19;: Authors: Werlinger F, Villalón M, Duarte V, Acevedo R, Aguilera R, Alcocer D, Badillo O, Briones R, Condal C, Del Río M, García R, Herrera M, Jaramillo J, Merchan F, Nasi M, Osbén R, Rivera A, Riviello S, Rojas P, Vidal C, Rodríguez G, Schild S, Arroyo E, Alvarado MJ, Sepúlveda P, Cortés...
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Related ArticlesOrofacial features and medical profile of eight individuals with Kabuki syndrome. Med Oral Patol Oral Cir Bucal. 2019 Aug 19;: Authors: Silva-Andrade N, López-Ortega S, Gallottini M Abstract BACKGROUND: To evaluate oral, craniofacial and systemic characteristics of eight patients with Kabuki syndrome (KS), aged between 3 and 16 years old. MATERIAL AND METHODS: in this retrospective study, medical records of all patients were...
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