As a leading cause of loss of functional movement, stroke often makes it difficult for patients to walk. Interventions to aid motor recovery in stroke patients should be carried out as a matter of urgency. However, muscle activity in the knee is usually too weak to generate overt movements, which poses a challenge for early post-stroke rehabilitation training. Although electromyography (EMG)-controlled exoskeletons have the potential to solve this problem, most existing robotic devices in rehabilitation...
now
Myocontrol is control of a prosthetic device by a disabled user using data obtained non- or minimally-invasively from (residual) muscle activity. In most myocontrol prosthetic systems, such biological data also denote the subject’s intent: reliably interpreting what the user wants to do, exactly and only when she wants, is paramount to avoid instability, potentially leading to accidents, humiliation and trauma. Indeed, instability manifests itself as a failure of the myocontrol in interpreting the...
now
Abstract Background Whole-body MRI is used for staging paediatric Hodgkin lymphoma, commonly using size thresholds, which fail to detect disease in normal-size lymph nodes. Objective To investigate quantitative whole-body MRI metrics for nodal characterisation. Materials and...
now
Abstract In recent years as a result of decreasing prices and the increasing availability of portable systems, ultrasonography (US), which historically has primarily been the domain of radiologists, has become more widely available to non-radiologists as well. This has increased the use of point-of-care paediatric US performed by non-radiologists. With this scoping review, focused on abdominal imaging, we aim to gain an overview of the current practices in the paediatric setting...
now
Abstract Background Knowledge of ovarian volume is important for diagnostic evaluations; however, normal ovarian volume studies on children and adolescents are lacking. Objective This study aimed to analyze age-specific ovarian volume and identify the diverse factors that contribute to ovarian diagnoses. ...
now
Abstract Hepatocyte-specific contrast agents (HSCAs) are a group of intravenous gadolinium-based MRI contrast agents that can be used to characterize hepatobiliary pathology. The mechanism by which these agents are taken up by hepatocytes and partially excreted into the biliary tree improves characterization of hepatic lesions and biliary abnormalities relative to conventional extracellular gadolinium-based contrast agents (GBCAs). This manuscript presents an overview of HSCA...
now
ConclusionsOur results suggested that TNBG ‐5602 might exert potent anticancer activity through increasing the expression of PPARγ. (Source: Journal of Pharmacy and Pharmacology)
15h
ConclusionOur findings revealed the lack of systematic approach towards purchasing agreements, and a limited use of potentially powerful mechanisms such as joint negotiations. Furthermore, a large majority of patient representatives (79%) and providers (66%) indicated that the drug cost issue is likely to influence treatments decisions. Access issues and coverage delays seem to be present in all countries regardless of level of GDP. (Source: Journal of Cancer Policy)MedWorm Message: If you are looking...
16h
(Source: Cancer Management and Research)
16h
(Source: OncoTargets and Therapy)MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
16h
(Source: Cancer Management and Research)
16h
(Source: Cancer Management and Research)
16h
AbstractIt is well recognized that CD4+ T cells may play an important role in immunosurveillance and immunotherapy against cancer. However, the details of how these cells recognize and eliminate the tumor cells remain incompletely understood. For the past 25 years, we have focused on how CD4+ T cells reject multiple myeloma cells in a murine model (MOPC315). In our experimental system, the secreted tumor-specific antigen is taken up by tumor-infiltrating macrophages that process it and present a...
16h
Authors: Tian Liu Yiwei Wang Yubing Wang Andrew M. Chan Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) is a tumor suppressor gene frequently found to be inactivated in over 30% of human cancers. PTEN encodes a 54-kDa lipid phosphatase that serves as a gatekeeper of the phosphoinositide 3-kinase pathway involved in the promotion of multiple pro-tumorigenic phenotypes. Although the PTEN protein plays a pivotal role in carcinogenesis, cumulative evidence has implicated...
16h
ConclusionOur findings provide the proof-of-concept rationale and previously undiscovered mechanisms for co-targeting sMIC to enable and enhance the response to PD1/PD-L1 blockade therapy in sMIC+ cancer patients. (Source: Journal for Immunotherapy of Cancer)
16h
ConclusionsThe present cohort study suggests a protective effect of green tea against hematologic neoplasms, especially acute myeloid leukemias. (Source: Cancer Causes and Control)
16h
ConclusionsFor intermediate-risk as well as early stage high-risk BC patients, the DEGRO Breast Cancer Expert Panel recommends the use of PMRT following SSME and NSME when a 10-year locoregional recurrence risk is likely to be greater than 10%, as estimated by clinical and biological risk factors. Subvolume-only radiation is discouraged outside of trials. The impact of adequate systemic treatment and the value of radiotherapy on optimal locoregional tumor control, wit h the goal of less than 5%...
16h
. (Source: Nutrition and Cancer)
16h
Authors: Oliver Millan Catalan Alma D. Campos-Parra Rafael Vázquez-Romo David Cantú de León Nadia Jacobo-Herrera Fermín Morales-González César López-Camarillo Mauricio Rodríguez-Dorantes Eduardo López-Urrutia Carlos Pérez-Plasencia The presence of germline and somatic deleterious mutations in the BRCA1 and BRCA2 genes has important clinical consequences for breast cancer (BC) patients. Analysis of the mutational status in BRCA genes is not yet common in public...
16h
The etiology of adenocarcinoma of the cardia and the gastroesophageal junction (GEJ) is not known and is doubted. It is thought that cardia gastric adenocarcinoma (CGA) is distinct from adenocarcinomas located in the esophagus or distal stomach, both epidemiologically and biologically. Moreover, CGA is often identified in the advanced stage having a poor prognosis. In this paper, we would like to ascertain the possible role of GC family history, lifestyle, demographics, gastroesophageal reflux disease,Helicobacter...
16h
ConclusionsOur results suggested that there exists at least a selective group of stage IV gastric SRCC patients, who could benefit from palliative gastrectomy followed by chemotherapy compared to chemotherapy alone. Further prospective trials are needed to support our conclusion. (Source: Cancer Medicine)MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps...
16h
ConclusionsThe present study demonstrated that miR ‐181 could be a promising biomarker with predictive value for prognosis for CRC patients. However, future studies comprising large cohorts from multicenter are warranted to further investigate the biomarker value of miR‐181. (Source: Cancer Medicine)
16h
Nature genetics
1h
Nature climate change
1h
Nature metabolism
1h
Nature human behaviour
1h
Nature genetics
1h
The International Journal of Behavioral Nutrition and Physical Activity
1h
1h
1h
1h
1h
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου