Related ArticlesUpper GI biopsies for adenocarcinoma - how many biopsies should endoscopists take? Histopathology. 2019 May;74(6):959-963 Authors: Kaye P, Lindsay D, Madhusudan S, Vohra R, Catton J, Platt C, Ragunath K Abstract AIMS: There is evidence that four or five gastric cancer biopsies are required for accurate HER2 interpretation. However, the number of biopsies that need to be taken to reach this number of viable cancer biopsies is without...
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Related ArticlesBarrett's Esophagus. Mo Med. 2018 May-Jun;115(3):211-213 Authors: Bujanda DE, Hachem C Abstract The prevalence of Barrett's esophagus is increasing in the United States and is a major risk factor for esophageal adenocarcinoma. This review serves to help primary care physicians and family practitioners better understand who should be screened for Barrett's esophagus, know the appropriate surveillance intervals for repeat endoscopy, and...
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Related ArticlesResponse to: "Colonic Interposition After Adult Oesophagectomy: Systematic Review and Meta-analysis of Conduit Choice and Outcome". J Gastrointest Surg. 2018 11;22(11):2002 Authors: Fisher RA, Gossage J, Griffiths E AbstractPMID: 30076590 [PubMed - indexed for MEDLINE]
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Related ArticlesVenous Malformation of the Esophagus. Ann Thorac Surg. 2018 08;106(2):e69-e71 Authors: Cano Busnelli V, Medici J, Duro A, Castellaro P, Wright F, Cavadas D, Beskow A Abstract Venous malformations are an extremely infrequent condition in the gastrointestinal tract, particularly in the esophagus. We report a rare case of an adult with an asymptomatic mass located in the mediastinum and in whom the diagnosis and treatment of a venous malformation...
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Related ArticlesVerrucous carcinoma of the esophagus: A rare entity with a difficult diagnosis. Cir Esp. 2018 Aug - Sep;96(7):453-455 Authors: Paseiro Crespo G, Nebreda MG, Barceló López M, Marqués Medina E, Gimeno Aranguez M PMID: 29452967 [PubMed - indexed for MEDLINE]
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Related ArticlesNovel variant p.E269K confirms causative role of PLS1 mutations in autosomal dominant hearing loss. Clin Genet. 2019 Aug 21;: Authors: Diaz-Horta O, Bademci G, Tokgoz-Yilmaz S, Guo S, Zafeer F, Sineni CJ, Duman D, Farooq A, Tekin M Abstract Auditory reception relies on the perception of mechanical stimuli by stereocilia and its conversion to electrochemical signal. Mechanosensory stereocilia are abundant in actin, which provides them...
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Related ArticlesA unique case of vision loss in a patient with hypotrichosis and juvenile macular dystrophy and primary ciliary dyskinesia. Am J Ophthalmol Case Rep. 2019 Sep;15:100486 Authors: Fan KC, Patel NA, Yannuzzi NA, Prakhunhungsit S, Negron CI, Basora E, Colin AA, Tekin M, Berrocal AM Abstract Purpose: We describe a unique case of CDH3-related hypotrichosis with juvenile macular dystrophy (HJMD) and DNAH5-related primary ciliary dyskinesia (PCD)...
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Related ArticlesPublic health round-up. Bull World Health Organ. 2019 Apr 01;97(4):248-249 Authors: PMID: 30940979 [PubMed - indexed for MEDLINE]
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Related ArticlesModelling high pathogenic avian influenza outbreaks in the commercial poultry industry. Theor Popul Biol. 2019 04;126:59-71 Authors: Barnes B, Scott A, Hernandez-Jover M, Toribio JA, Moloney B, Glass K Abstract Highly pathogenic avian influenza (HPAI) outbreaks are devastating to poultry industries and pose a risk to human health. There is concern that demand for free-range poultry products could increase the number of HPAI outbreaks...
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Related ArticlesModelling the outbreak of infectious disease following mutation from a non-transmissible strain. Theor Popul Biol. 2019 04;126:1-18 Authors: Chen CY, Ward JP, Xie WB Abstract In-host mutation of a cross-species infectious disease to a form that is transmissible between humans has resulted with devastating global pandemics in the past. We use simple mathematical models to describe this process with the aim to better understand the emergence...
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Related ArticlesEnhanced Safety Surveillance of Seasonal Quadrivalent Influenza Vaccines in English Primary Care: Interim Analysis. Adv Ther. 2018 Aug;35(8):1199-1214 Authors: de Lusignan S, Dos Santos G, Byford R, Schuind A, Damaso S, Shende V, McGee C, Yonova I, Ferreira F Abstract INTRODUCTION: The European Medicines Agency (EMA) requires vaccine manufacturers to conduct enhanced safety surveillance (ESS) of seasonal influenza vaccines including...
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Related Articles[New frontiers in the fight against cancer]. Biol Aujourdhui. 2018;212(3-4):61-67 Authors: Chiossone L, Vivier E Abstract After many years of research, recent advances shed a new light on the role of the immune system in cancer. New therapeutic antibodies, such as anti-PD-1/L1, that block the interactions of inhibitory receptors (immune checkpoint inhibitors, ICI) with their ligands, have revolutionized the management of cancer patients....
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Pembrolizumab in lung cancer: current evidence and future perspectives. Future Oncol. 2019 Aug 21;: Authors: Palumbo G, Carillio G, Manzo A, Montanino A, Sforza V, Costanzo R, Sandomenico C, Manna C, Luca G, Piccirillo MC, Daniele G, Cecio R, Botti G, Totaro G, Muto P, Picone C, Esposito G, Normanno N, Morabito A Abstract Pembrolizumab is a humanized monoclonal antibody against PD-1 capable of enhancing antitumor immune activity. The KEYNOTE-001 study...
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Glasdegib in the treatment of acute myeloid leukemia. Future Oncol. 2019 Aug 21;: Authors: Wolska-Washer A, Robak T Abstract Pharmacologic inhibition of the Hedgehog pathway significantly enhanced the sensitivity of leukemic cells to cytotoxic drugs. Glasdegib (PF-04449913; DAURISMO™) is a potent and selective oral inhibitor of the Hedgehog signaling pathway with clinical activity in patients with acute myeloid leukemia (AML) and myelodysplastic syndrome...
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Neratinib-based therapy in patients with metastatic HER2-positive breast cancer from Asia. Future Oncol. 2019 Aug 21;: Authors: Xu B, Kim SB, Inoue K, Lee J, Zhang B, Bryce R, Chow LW Abstract Aim: To evaluate the safety and efficacy of neratinib-based therapy in Asian patients with HER2-positive metastatic breast cancer (MBC). Patients & methods: We performed a pooled analysis of seven early-phase studies of neratinib given either as monotherapy...
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Related ArticlesSignificance of FLT3-tyrosine kinase domain mutation as a prognostic factor for acute myeloid leukemia. Int J Hematol. 2019 Aug 20;: Authors: Sakaguchi M, Yamaguchi H, Kuboyama M, Najima Y, Usuki K, Ueki T, Oh I, Mori S, Kawata E, Uoshima N, Kobayashi Y, Kako S, Tajika K, Shono K, Kayamori K, Hagihara M, Kanda J, Uchiyama H, Kuroda J, Uchida N, Kubota Y, Kimura S, Kurosawa S, Date K, Nakajima N, Marumo A, Omori I, Fujiwara Y, Terada K, Yui S, Wakita S,...
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Related ArticlesHaploidentical hematopoietic stem cell transplantation with αβTCR+/CD19+ depletion in pediatric patients with malignant and non-malignant disorders. Bone Marrow Transplant. 2019 Aug;54(Suppl 2):694-697 Authors: Bielorai B, Jacoby E, Varda-Bloom N, Hutt D, Churi C, Vernitsky H, Toren A Abstract Haploidntical hematopoietic stem cell transplantation has been increasingly used in recent years for patients without a matched donor. The αβTCR+/CD19+...
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Related ArticlesPseudoprogression after radiation therapies for low grade glioma in children and adults: A systematic review and meta-analysis. Radiother Oncol. 2019 Aug 17;: Authors: Lu VM, Welby JP, Laack NN, Mahajan A, Daniels DJ Abstract BACKGROUND: Pseudoprogression (PsP) following radiation therapy (RT) for low grade glioma (LGG, WHO grade I and II), including both photon-based intensity-modulated RT (IMRT) and proton beam therapy (PBT), has been...
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