MéthotrexateScienceDirect Publication: Annales de De.. - 16m ago AUTO POST SAVE TO EVERNOTEPublication date: Available online 14 June 2019Source: Annales de Dermatologie et de VénéréologieAuthor(s): M. Beylot-Barry, M. Le Maitre, C. Goujon, Groupe de recherche sur le psoriasis de la Société française de dermatologieRead Full Article Visit websiteShow original. Share. Favorite. Email . BrodalumabScienceDirect Publication: Annales de De.. - 16m ago AUTO POST SAVE TO EVERNOTEPublication date: Available...
Identification of novel oligopeptides from the simulated digestion of sea cucumber (Stichopus japonicus) to alleviate Aβ aggregation progressionFunctional Foods - 15m ago Preview AUTO POST SAVE TO EVERNOTEPublication date: September 2019Source: Journal of Functional Foods, Volume 60Author(s): Xiaoling Lin, Maojin Yao, Jia-Hong Lu, Yi Wang, Xiquan Yin, Ming Liang, Erdong Yuan, Jiaoyan RenAbstractThe aim of this study was to isolate and identify peptides from sea cucumber hydrolysates prepared...
Markerless pancreatic tumor target localization enabled by deep learningScienceDirect Publication: International.. - 13m ago Preview AUTO POST SAVE TO EVERNOTEPublication date: Available online 13 June 2019Source: International Journal of Radiation Oncology*Biology*PhysicsAuthor(s): Wei Zhao, Liyue Shen, Bin Han, Yong Yang, Kai Cheng, Diego AS. Toesca, Albert C. Koong, Daniel T. Chang, Lei XingAbstractPurposeTo estimate the impact of radiotherapy (RT) on non-breast second malignant neoplasms...
SécukinumabScienceDirect Publication: Annales de De.. - 13m ago Preview AUTO POST SAVE TO EVERNOTEPublication date: Available online 14 June 2019Source: Annales de Dermatologie et de VénéréologieAuthor(s): L. Meunier, Groupe de recherche sur le psoriasis de la Société française de dermatologieRead Full Article Visit website
Polysaccharides from Poria cocos (PCP) inhibits ox-LDL-induced vascular smooth muscle cells proliferation and migration by suppressing TLR4/NF-κB p65 signaling pathwayFunctional Foods - 13m ago Preview AUTO POST SAVE TO EVERNOTEPublication date: September 2019Source: Journal of Functional Foods, Volume 60Author(s): Weifeng Li, Jinmeng Zhao, Qing Yao, Wenqi Li, Wenbing Zhi, Lulu Zang, Fang Liu, Xiaofeng NiuAbstractVascular smooth muscle cells (VSMCs) proliferation and migration causes the tunica...
CiclosporineScienceDirect Publication: Annales de De.. - 13m ago Preview AUTO POST SAVE TO EVERNOTEPublication date: Available online 14 June 2019Source: Annales de Dermatologie et de VénéréologieAuthor(s): Carle Paul, Groupe de recherche sur le psoriasis de la Société française de dermatologieRead Full Article Visit website
Small black bean (Rhynchosia volubilis) extract ameliorates gut microbial and metabolic perturbation in ovariectomized miceFunctional Foods - 13m ago Preview AUTO POST SAVE TO EVERNOTEPublication date: September 2019Source: Journal of Functional Foods, Volume 60Author(s): Kwang Hyun Cha, Kyung-A Kim, Suk Woo Kang, Seemi Tasnim Alam, Jong Beom Jin, Gyhye Yoo, Sang Hoon Jung, Cheol-Ho Pan, Kyungsu KangAbstractPhytoestrogen is considered a promising natural remedy for various postmenopausal symptoms....
Chromosome Mapping of H1 and H4 Histones in Parodontidae (Actinopterygii: Characiformes): Dispersed and/or Co-Opted Transposable Elements?CGR : Last 20 articles by S.karger Ag - 13m ago Preview AUTO POST SAVE TO EVERNOTEThe karyotypes of the family Parodontidae consist of 2n = 54 chromosomes. The main chromosomal evolutionary changes of its species are attributed to chromosome rearrangements in repetitive DNA regions in their genomes. Physical mapping of the H1 and H4 histones was performed in...
Unravelling the Role of MAPKs (ERK1/2) in Venous Reflux in Patients with Chronic Venous DisorderCTO : Last 20 articles by S.karger Ag - 13m ago Preview AUTO POST SAVE TO EVERNOTEChronic venous disorder (CVeD), is a disorder in which there is a modification in the conditions of blood return to the heart. The disorder may arise from incompetent valves and the resultant venous reflux (chronic venous insufficiency, CVI). The economic burden of CVeD on health systems is high, and research efforts...
Primary Hypertrophic Osteoarthropathy Mimicking Juvenile Idiopathic Arthritis: A Novel SLCO2A1 Mutation and Imaging FindingsCGR : Last 20 articles by S.karger Ag - 13m ago Preview AUTO POST SAVE TO EVERNOTEPrimary hypertrophic osteoarthropathy (PHO), also known as pachydermoperiostosis, is a rare, multisystemic, autosomal recessive condition typically presenting with digital clubbing, osteoarthropathy, and various skin manifestations. Radiographs show distinctive periosteal reaction and thickening...
Assessment of the methodological quality of local clinical practice guidelines on the identification and management of gestational diabetesBMJ Open Current Issue by Daley, B., Hitman, G., Fenton, N., .. - 16m ago Preview AUTO POST SAVE TO EVERNOTEObjectiveGestational diabetes is the most common metabolic disorder of pregnancy, and it is important that well-written clinical practice guidelines (CPGs) are used to optimise healthcare delivery and improve patient outcomes. The aim of the study was...
Synchronous splenic metastasis of endometrial carcinomaBMJ Case Reports by Pissarra, A. P., Cunha, T. M., Mata.. - 16m ago Preview AUTO POST SAVE TO EVERNOTERead Full Article Visit website
Altered Levels of Proteins and Phosphoproteins, in the Absence of Early Causative Transcriptional...
Altered Levels of Proteins and Phosphoproteins, in the Absence of Early Causative Transcriptional Changes, Shape the Molecular Pathogenesis in the Brain of Young Presymptomatic Ki91 SCA3/MJD MouseLatest Results for Molecular Neurobiolog.. - 16m ago Preview AUTO POST SAVE TO EVERNOTEAbstractSpinocerebellar ataxia type 3 (SCA3/MJD) is a polyQ neurodegenerative disease where the presymptomatic phase of pathogenesis is unknown. Therefore, we investigated the molecular network of transcriptomic and...
Modeling Alzheimer's disease with human iPS cells: advancements, lessons, and applicationsNeurobiology of Disease - 16m ago Preview AUTO POST SAVE TO EVERNOTEPublication date: Available online 13 June 2019Source: Neurobiology of DiseaseAuthor(s): Sofia Essayan-Perez, Bo Zhou, Amber M. Nabet, Marius Wernig, Yu-Wen Alvin HuangAbstractOne in three people will develop Alzheimer's disease (AD) or another dementia and, despite intense research efforts, treatment options remain inadequate. Understanding...
Adults Who Played Pokémon Extensively In Childhood Have A Pokémon-Sensitive Region In Their Visual Cortexpsychology by /u/dwaxe - 16m ago Preview AUTO POST SAVE TO EVERNOTEsubmitted by /u/dwaxe [visit reddit] [comments]Read Full Article Visit website
Limiting radiotherapy field to ipsilateral side only in unresected lateralised HPV positive N2b squamous cell carcinoma of the tonsilOral Oncology - 16m ago Preview AUTO POST SAVE TO EVERNOTEPublication date: Available online 12 June 2019Source: Oral OncologyAuthor(s): Muhammad Shahid Iqbal, Josef Kovarik, Charles KellyRead Full Article Visit website
Enlarged anterior cranial fossa and restricted posterior cranial fossa, the disproportionate growth of basicranium in Crouzon syndromeScienceDirect Publication Journal of Cra.. - 16m ago Preview AUTO POST SAVE TO EVERNOTEPublication date: Available online 14 June 2019Source: Journal of Cranio-Maxillofacial SurgeryAuthor(s): Xiaona Lu, Antonio Jorge Forte, Derek M. Steinbacher, Michael Alperovich, Nivaldo Alonso, John A. PersingSummaryCrouzon syndrome patients develop normal intracranial volume...
Hypothyroidism manifesting as multiple cranial neuropathies: a case reportJournal of Medical Case Reports - Latest.. by Matthias Hepprich, Johannes Lorsche.. - 14m ago Preview AUTO POST SAVE TO EVERNOTEThe clinical picture of hypothyroidism, including neurological symptoms, can be multiform, which may delay or hamper the correct diagnosis.Read Full ArticleVisit websiteIntroductionThe clinical picture of hypothyroidism, including neurological symptoms, can be multiform, which may delay or hamper...
Leiomyosarcoma: Prognostic outline of a rare head and neck malignancyOral Oncology - 14m ago Preview AUTO POST SAVE TO EVERNOTEPublication date: August 2019Source: Oral Oncology, Volume 95Author(s): Tajindra Singh Saluja, Janaki Iyer, Satyendra Kumar SinghAbstractSoft tissue sarcomas (STS) are mesenchymal malignant neoplasms with a broad spectrum of biologic behaviour. Most STS show predilection for extremities with rarity in head and neck. Leiomyosarcoma (LMS) is an extremely rare STS in head...
Preparation, characterization, in vitro bioactivity and protein loading/release property of mesoporous bioactive glass microspheres with different compositionsPowder Technology - 14m ago Preview AUTO POST SAVE TO EVERNOTEPublication date: Available online 13 June 2019Source: Advanced Powder TechnologyAuthor(s): Guohou Miao, Zhengmao Li, Yongchun Meng, Jingwen Wu, Yuli Li, Qing Hu, Xiaofeng Chen, Xuechao Yang, Xiaoming ChenAbstractMesoporous bioactive glass microspheres (MBGMs) with large mesopores...
Particle dynamics in a multi-staged fluidized bed: Particle transport behavior on micro-scale by discrete particle modellingPowder Technology - 14m ago Preview AUTO POST SAVE TO EVERNOTEPublication date: Available online 13 June 2019Source: Advanced Powder TechnologyAuthor(s): E. Diez, P. Kieckhefen, K. Meyer, A. Bück, E. Tsotsas, S. HeinrichAbstractThis work studies the particle exchange rates in horizontal fluidized beds equipped with different weir designs between compartments. These particle...
Antitumor activity of dual blockade of PD-L1 and MEK in NSCLC patients derived three-dimensional spheroid culturesLatest Results for Journal of Ex... - 14m ago Preview AUTO POST SAVE TO EVERNOTEAbstract BackgroundAnti-PD-1/PD-L1 drugs are effective as monotherapy in a proportion of NSCLC patients and there is a strong rationale for combining them with targeted therapy. Inhibition of MAPK pathway may have pleiotropic effects on the microenvironment. This work investigates the efficacy of combining...
Curcumin overcome primary gefitinib resistance in non-small-cell lung cancer cells through inducing autophagy-related cell deathLatest Results for Journal of Ex... - 14m ago Preview AUTO POST SAVE TO EVERNOTEAbstract BackgroundEpidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are being wildly used as target therapy in non-small-cell lung cancer (NSCLC). However, NSCLC patients with wild-type EGFR and KRAS mutation are primary resistant to EGFR-TKIs such as gefitinib. Curcumin...
Hepatic pathology and altered gene transcription in a murine model of acid ceramidase deficiency....
Hepatic pathology and altered gene transcription in a murine model of acid ceramidase deficiency.pubmed lab invest [jour].. - 14m ago Preview AUTO POST SAVE TO EVERNOTERelated ArticlesHepatic pathology and altered gene transcription in a murine model of acid ceramidase deficiency.Lab Invest. 2019 Jun 11;:Authors: Yu FPS, Molino S, Sikora J, Rasmussen S, Rybova J, Tate E, Geurts AM, Turner PV, Mckillop WM, Medin JAAbstractFarber disease (FD) is a rare lysosomal storage disorder (LSD) characterized...
Combination of CTLA-4 and PD-1 blockers for treatment of cancerLatest Results for Journal of Ex... - 14m ago Preview AUTO POST SAVE TO EVERNOTEAbstractTargeting checkpoints of immune cell activation has been demonstrated to be the most effective approach for activation of anti-tumor immune responses. Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and programmed cell death protein 1 (PD-1), both inhibitory checkpoints commonly seen on activated T-cells have been found to be the most reliable...
Co-staining of microRNAs and their target proteins by miRNA in situ hybridization and immunohistofluorescence on prostate cancer tissue microarrays.pubmed lab invest [jour].. - 14m ago Preview AUTO POST SAVE TO EVERNOTERelated ArticlesCo-staining of microRNAs and their target proteins by miRNA in situ hybridization and immunohistofluorescence on prostate cancer tissue microarrays.Lab Invest. 2019 Jun 11;:Authors: Eckstein M, Sailer V, Nielsen BS, Wittenberg T, Wiesmann V, Lieb V, Nolte E, Hartmann...
PTENP1/miR-20a/PTEN axis contributes to breast cancer progression by regulating PTEN via PI3K/AKT...
PTENP1/miR-20a/PTEN axis contributes to breast cancer progression by regulating PTEN via PI3K/AKT pathwayLatest Results for Journal of Ex... - 14m ago Preview AUTO POST SAVE TO EVERNOTEAbstract BackgroundLong non-coding RNA PTENP1, the pseudogene of PTEN tumor suppressor, has been reported to exert its tumor suppressive function via modulation of PTEN expression in many malignancies, including breast cancer (BC). However, whether the PTENP1/miR-20a/PTEN axis exists and how it functions in BC...
SIRT7 regulates hepatocellular carcinoma response to therapy by altering the p53-dependent cell death pathwayLatest Results for Journal of Ex... - 11m ago Preview AUTO POST SAVE TO EVERNOTEAbstract BackgroundOptimal therapeutic strategies for hepatocellular carcinoma (HCC) patients are still challenging due to the high recurrence rate after surgical resection and chemotherapy resistance. Growing evidence shows that genetic and epigenetic alterations are involved in HCC progression and resistance...
Fractional CO2 laser treatment for post-surgical lip scars in cleft lip and palate patients.pubmed lasers med sci [jou..... - 11m ago Preview AUTO POST SAVE TO EVERNOTERelated ArticlesFractional CO2 laser treatment for post-surgical lip scars in cleft lip and palate patients.Lasers Med Sci. 2019 Jun 11;:Authors: Jahanbin A, Eslami N, Layegh P, Saeidi M, Kazemi M, Shahabi M, Raisolsadat SMAAbstractPost-surgical scars of cleft lip patients can lead to abnormal lip activity, which causes deficient...
Colorectal cancer-derived extracellular vesicles induce transformation of fibroblasts into colon carcinoma cellsLatest Results for Journal of Ex... - 11m ago Preview AUTO POST SAVE TO EVERNOTEAbstract BackgroundWe reported that horizontal transfer of malignant traits to target cells is a potential pathway to explain cancer dissemination. Although these results were encouraging, they were never corroborated by data showing the molecular mechanisms responsible for the observed phenomenon.MethodsIn...
Constraints and opportunities in gender relations: Sugarcane outgrower schemes in MalawiWorld Development - 11m ago Preview AUTO POST SAVE TO EVERNOTEPublication date: October 2019Source: World Development, Volume 122Author(s): Timothy Adams, Jean-David Gerber, Michèle AmackerAbstractContract farming (CF) is always and inherently a gendered process. This paper unveils the gender dynamics in resource access, use and labour control to show how outgrower CF induces changes, often contradictory engendering...
Obstructive sleep apnoea syndrome and endothelial function: potential impact of different treatment strategies—meta-analysis of prospective studiesLatest Results for European Arch... - 11m ago Preview AUTO POST SAVE TO EVERNOTEAbstract PurposePrevious studies have shown an association between obstructive sleep apnoea syndrome (OSAS) and cardiovascular events. Whether this association is mediated by an impairment of endothelial function, which is itself a driver of elevated cardiovascular risk,...
Multiplex quantitative analysis of stroma-mediated cancer cell invasion, matrix remodeling, and drug response in a 3D co-culture model of pancreatic tumor spheroids and stellate cellsLatest Results for Journal of Ex... - 11m ago Preview AUTO POST SAVE TO EVERNOTEAbstract BackgroundPancreatic ductal adenocarcinoma (PDAC) is a stroma-rich carcinoma, and pancreatic stellate cells (PSCs) are a major component of this dense stroma. PSCs play significant roles in metastatic progression and chemoresistance...
Temporary blood–brain barrier disruption by low intensity pulsed ultrasound increases carboplatin...
Temporary blood–brain barrier disruption by low intensity pulsed ultrasound increases carboplatin delivery and efficacy in preclinical models of glioblastomaLatest Results for Journal of Neuro-Onco.. - 10m ago Preview AUTO POST SAVE TO EVERNOTEAbstract IntroductionGlioblastoma (GBM) is the most common and aggressive primary brain cancer in adults. Few cytotoxic chemotherapies have been shown to be effective against GBM, due in part to the presence of the blood–brain barrier (BBB), which reduces...
Parthenogenesis as a solution to hybrid sterility: the mechanistic basis of meiotic distortions in clonal and sterile hybrids ,bioRxiv Subject Collection: Evolutionary.. by Dedukh, D., Majtanova, Z., Marta, A.. - 10m ago Preview AUTO POST SAVE TO EVERNOTEFormation of species generally occurs in a continuum from potentially intermixing populations to independent entities isolated from other species by pre- and postzygotic barriers. Especially the establishment of hybrid sterility (HS) is a hallmark...
Protein structure from experimental evolution,bioRxiv Subject Collection: Evolutionary.. by Stiffler, M. A., Poelwijk, F. J., B.. - 8m ago Preview AUTO POST SAVE TO EVERNOTENatural evolution encodes rich information about the structure and function of biomolecules in the genetic record. Previously, statistical analysis of co-variation patterns in natural protein families has enabled the accurate computation of 3D structures. Here, we explored whether similar information can be generated by laboratory...
Premeiotic and meiotic failures lead to hybrid male sterility in the Anopheles gambiae complex ,bioRxiv Subject Collection: Evolutionary.. by Liang, J., Sharakhov, I. V. - 8m ago Preview AUTO POST SAVE TO EVERNOTEHybrid male sterility contributes to speciation by restricting gene flow between related taxa. Detailed cytological characterizations of reproductive organs in hybrid males is important for identifying phenotypes that can help guide searches of speciation genes. To investigate possible...
Κενά παιδιά»: Το άρθρο του ψυχιάτρου Λουίς Ρόχας ΜάρκοςΥπάρχει μια σιωπηλή τραγωδία που εκτυλίσσεται σήμερα στα σπίτια μας και αφορά στα πιο πολύτιμα «κοσμήματά» μας: τα παιδιά μας. Τα παιδιά μας βρίσκονται σε μια συναισθηματική κατάσταση καταστροφική!Τα τελευταία 15 χρόνια, οι ερευνητές μας πρόσφεραν στατιστικές κάθε φορά και πιο ανησυχητικές σχετικά με την οξυμένη και επίμονη αύξησης παιδικής ψυχασθένειας που τώρα έχει φτάσει αναλογίες επιδημίας:Οι στατιστικές δεν ψεύδονται:• 1 κάθε 5 παιδιά έχει...
Evolutionary games with environmental feedbacks ,bioRxiv Subject Collection: Evolutionary.. by Tilman, A. R., Plotkin, J., Akcay, .. - 8m ago Preview AUTO POST SAVE TO EVERNOTEStrategic interactions form the basis for evolutionary game theory and often occur in dynamic environments. The various strategies employed in a population may alter the quality or state of the environment, which may in turn feedback to change the incentive structure of strategic interactions. This type of feedback is common...
Mannitol triggers mast cell-dependent contractions of human small bronchi and prostacyclin bronchoprotectionJournal of Allergy and Clinical Immunolo.. - 8m ago Preview AUTO POST SAVE TO EVERNOTEPublication date: Available online 14 June 2019Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Jesper Säfholm, Martijn L. Manson, Johan Bood, Mamdoh Al-Ameri, Ann-Charlotte Orre, Johan Raud, Sven-Erik Dahlén, Mikael AdnerAbstractBackgroundClinical research supports that exercise-induced bronchoconstriction...
Effect of single-dose intravenous tranexamic acid on postoperative nasal bleed in septoplastyEuropean Annals of Otorhinolaryngology, .. - 8m ago Preview AUTO POST SAVE TO EVERNOTEPublication date: Available online 14 June 2019Source: European Annals of Otorhinolaryngology, Head and Neck DiseasesAuthor(s): S.U. Zaman, I. Zakir, Q. Faraz, S. Akhtar, A. Nawaz, M. AdeelAbstractObjectivePostoperative nasal bleeding is a common complication of septoplasty and may lead to painful procedure of nasal...
Microbleeds after Carotid Artery Stenting: Small Embolism May Induce Cerebral MicrobleedsCEE : Last 20 articles by S.karger Ag - 8m ago Preview AUTO POST SAVE TO EVERNOTEBackground: Since the advent of magnetic resonance imaging technology, cerebral microbleeds can be diagnosed in vivo. However, the underlying mechanism of cerebral microbleed formation is not fully understood. Objectives: This study aimed to identify the factors associated with cerebral microbleeds after carotid artery stenting...
Business Wire Health: Clinic..Global Muscle Spasticity Clinical Trial Pipeline Highlights, 2019 - Analysis on Clinical Trial Stages, Drug Mechanism Classes, Short-term Launch Highlights, and Companies - ResearchAndMarkets.com DUBLIN--(BUSINESS WIRE)--The "Global Muscle Spasticity Clinical Trial Pipeline Highlights, 2019" report has been added to ResearchAndMarkets.com's offering. This report provides most up-to-date..2m Business Wire Health: Clinic..Global Actinic Keratosis Clinical Trial Pipeline...
Global Genital Warts Clinical Trial Pipeline Highlights, 2019 - Analysis on Clinical Trial Stages, Drug Mechanism Classes, Short-term Launch Highlights, and Companies - ResearchAndMarkets.comDUBLIN--(BUSINESS WIRE)--The "Global Genital Warts Clinical Trial Pipeline Highlights, 2019" report has been added to ResearchAndMarkets.com's offering. This report provides most up-to-date information on key pipeline products in the global Genital Warts market. It covers emerging therapies for Genital Warts...
Gout - Global Clinical Trial Pipeline Highlights, 2019: Track Competition, Identify Partners, Evaluate Opportunities, Formulate Business Development Strategies - ResearchAndMarkets.comBusiness Wire Health: Clinical Trials Ne.. - 1h ago Preview AUTO POST SAVE TO EVERNOTEDUBLIN--(BUSINESS WIRE)--The "Gout - Global Clinical Trial Pipeline Highlights, 2019" report has been added to ResearchAndMarkets.com's offering. This report provides most up-to-date information on key pipeline products in the...
Female Sexual Dysfunction - Global Clinical Trial Pipeline Highlights, 2019: Track Competition, Identify Partners, Evaluate Opportunities, Formulate Business Development Strategies - ResearchAndMarkets.comBusiness Wire Health: Clinical Trials Ne.. - 1h ago Preview AUTO POST SAVE TO EVERNOTEDUBLIN--(BUSINESS WIRE)--The "Female Sexual Dysfunction - Global Clinical Trial Pipeline Highlights, 2019" report has been added to ResearchAndMarkets.com's offering. This report provides most up-to-date information...
Hyperparathyroidism - Global Clinical Trial Pipeline Highlights, 2019: Track Competition, Identify Partners, Evaluate Opportunities, Formulate Business Development Strategies - ResearchAndMarkets.comBusiness Wire Health: Clinical Trials Ne.. - 1h ago Preview AUTO POST SAVE TO EVERNOTEDUBLIN--(BUSINESS WIRE)--The "Hyperparathyroidism - Global Clinical Trial Pipeline Highlights, 2019" report has been added to ResearchAndMarkets.com's offering. This report provides most up-to-date information on...
Liver Transplantation - Global Clinical Trial Pipeline Highlights, 2019: Track Competition, Identify Partners, Evaluate Opportunities, Formulate Business Development Strategies - ResearchAndMarkets.comBusiness Wire Health: Clinical Trials Ne.. - 1h ago Preview AUTO POST SAVE TO EVERNOTEDUBLIN--(BUSINESS WIRE)--The "Liver Transplantation - Global Clinical Trial Pipeline Highlights, 2019" report has been added to ResearchAndMarkets.com's offering. This report provides most up-to-date information...
Zika Virus - Global Clinical Trial Pipeline Highlights, 2019: Track Competition, Identify Partners, Evaluate Opportunities, Formulate Business Development Strategies - ResearchAndMarkets.comBusiness Wire Health: Clinical Trials Ne.. - 1h ago Preview AUTO POST SAVE TO EVERNOTEDUBLIN--(BUSINESS WIRE)--The "Zika Virus - Global Clinical Trial Pipeline Highlights, 2019" report has been added to ResearchAndMarkets.com's offering. This report provides most up-to-date information on key pipeline products...
Gonorrhea - Global Clinical Trial Pipeline Highlights, 2019: Track Competition, Identify Partners, Evaluate Opportunities, Formulate Business Development Strategies - ResearchAndMarkets.comBusiness Wire Health: Clinical Trials Ne.. - 1h ago Preview AUTO POST SAVE TO EVERNOTEDUBLIN--(BUSINESS WIRE)--The "Gonorrhea - Global Clinical Trial Pipeline Highlights, 2019" report has been added to ResearchAndMarkets.com's offering. This report provides most up-to-date information on key pipeline products...
LentiGlobin® Gene Therapy for Transfusion-Dependent β-Thalassemia (TDT) at 24th European Hematology Association (EHA) CongressBusiness Wire Health: Clinical Trials Ne.. - 1h ago Preview AUTO POST SAVE TO EVERNOTECAMBRIDGE, Mass.--(BUSINESS WIRE)--bluebird bio, Inc. (Nasdaq:BLUE) announced updated results from the completed Phase 1/2 Northstar (HGB-204) study, and new data from the Phase 3 Northstar-2 (HGB-207) and Phase 3 Northstar-3 (HGB-212) clinical studies of its LentiGlobin® gene therapy...
Whooping Cough - Global Clinical Trial Pipeline Highlights, 2019: Track Competition, Identify Partners, Evaluate Opportunities, Formulate Business Development Strategies - ResearchAndMarkets.comBusiness Wire Health: Clinical Trials Ne.. - 1h ago Preview AUTO POST SAVE TO EVERNOTEDUBLIN--(BUSINESS WIRE)--The "Whooping Cough - Global Clinical Trial Pipeline Highlights, 2019" report has been added to ResearchAndMarkets.com's offering. This report provides most up-to-date information on key pipeline...
Chikungunya Fever - Global Clinical Trial Pipeline Highlights, 2019: Track Competition, Identify Partners, Evaluate Opportunities, Formulate Business Development Strategies - ResearchAndMarkets.comBusiness Wire Health: Clinical Trials Ne.. - 1h ago Preview AUTO POST SAVE TO EVERNOTEDUBLIN--(BUSINESS WIRE)--The "Chikungunya Fever - Global Clinical Trial Pipeline Highlights, 2019" report has been added to ResearchAndMarkets.com's offering. This report provides most up-to-date information on key...
Star Trek's Starfleet logo spotted on Mars,News RSS : Today by Rt - 55m ago Preview AUTO POST SAVE TO EVERNOTE On the Red Planet's Hellas Planitia expanse, the Mars Reconnaissance Orbiter has spotted a rather conspicuous logo that will have trekkies jumping for joy, while rekindling old rivalries with the Star Wars fandom in the process. Read Full Article at RT.comRead Full Article Visit website
Μητρότητα. H δύναμη στην αδυναμία,Ψυχο-γραφήματα by Ρεβέκκα Τσοχαντάρη - 17m ago Preview AUTO POST SAVE TO EVERNOTE«Μητρότητα. H δύναμη στην αδυναμία»Συγγραφείς: Γεωργία Τσούμπα & Κατερίνα Τζωρτζακάκη(…) Μπορούμε όλοι μας, γυναίκες και άντρες, να αξιοποιήσουμε την παραδοσιακή ευκολία των γυναικών στην επικοινωνία μέσα από την αναγνώριση των συναισθημάτων μας και την κατάθεση των βιωμάτων μας, χωρίς αντιπαραθέσεις και μομφές προς τον σύντροφό μας, με σεβασμό στη διαφορετική αντίληψη, με τη...
Inflammatory chorioretinopathies (White Dot Syndromes), diagnosis and management: A review of the literatureBassey Fiebai, Safinatu Wada MohammedPort Harcourt Medical Journal 2019 13(1):1-6Background: The white dot syndromes or inflammatory chorioretinopathies are a heterogenous group of diseases of unknown aetiology, characterized by the appearance of white dots on the fundus. These group of disorders include, acute posterior multifocal placoid pigment epitheliopathy (APMPPE), serpiginous choroiditis,...
Post-adenotonsillectomy analgesia in children: The place of non-steroidal anti-inflammatory drugsUju Matilda Ibekwe, Ediriverere OghenekaroPort Harcourt Medical Journal 2019 13(1):41-45Background: Adenotonsillectomy and tonsillectomy are common surgeries carried out in children under 15 years of age with associated significant pains; therefore, adequate post-operative pain management is mandatory to ensure full recovery. Non-steroidal anti-inflammatory drugs (NSAIDs), being cheap and readily available,...
Compliance and effectiveness of syndromic approach in females with reproductive tract infectionsHarmanjeet Kaur, Divya GoelPort Harcourt Medical Journal 2019 13(1):37-40Background: India has strengthened its fight against sexually transmitted infections (STIs) and reproductive tract infections (RTIs) by implementing syndromic approach at peripheral health centres. However, effective control of STIs and RTIs still remains a huge challenge. One of the biggest hurdles could be patient compliance towards...
Clinical profile of patients with uterine rupture at a tertiary facility in North Central NigeriaFolorunsho B Adewale, Abiodun S Adeniran, Munirdeen A IjaiyaPort Harcourt Medical Journal 2019 13(1):32-36Background: Uterine rupture is a major obstetric emergency and an important cause of maternal and perinatal morbidity and mortality. Aim: To determine the prevalence, clinical presentation, management options and pregnancy outcomes following uterine rupture. Methods: It is a 5-year, descriptive, retrospective...
Fasting blood glucose profile of tuberculosis patients in Port Harcourt, NigeriaInumanye N Ojule, Arinze I OparaPort Harcourt Medical Journal 2019 13(1):26-31Background: The inter-relationship between tuberculosis (TB) and diabetes mellitus (DM) continues to trigger global interest, especially due to increasing prevalence of TB, propelled largely by the HIV epidemic and almost on an equal scale by the increasing incidence of diabetes worldwide, especially in the developing countries. Aim: The aim...
Knowledge, attitude and practice of home management of diarrhoea among mothers of under-fives in Samaru, Kaduna State, NigeriaVictoria Nanben Omole, Teyil Mary Wamyil-Mshelia, Grace Awawu Nmadu, Nafisat Ohunene Usman, Emmanuel Ayuba Andeyantso, Farouk AdiriPort Harcourt Medical Journal 2019 13(1):19-25Background: Diseases associated with diarrhoea rank second among the top five diseases which account for childhood morbidities and mortalities in developing countries. Home-based management of diarrhoea...
Analgesia for procedural pain: Current practice among Nigerian paediatriciansZakari Aliyu Suleiman, Israel Kayode Kolawole, Kazeem Adewale Adegboye, Muhammed Akanbi Adeboye, Chuma Everestus Onuchukwu, Surajudeen Bello, Aminudeen AbdulrahmanPort Harcourt Medical Journal 2019 13(1):13-18Background: Minor procedures such as venepuncture and lumbar puncture among others are routinely performed in the neonatal intensive care units (NICUs) and paediatric wards. These procedures are accompanied by varying...
Evaluation of the psychological distress experienced by spouses of women undergoing anaesthesia for caesarean sectionSotonye Fyneface-Ogan, Chukwuma Okeafor, Alfred Tamunoigbanibo AggoPort Harcourt Medical Journal 2019 13(1):7-12Background: Caesarean section (CS) could serve a challenging situation to spouses and family of women, more so as these women are meant to undergo anaesthesia. Little evidence exists with regard to the psychological impact of this on these families. Aim: The study was aimed...
Inflammatory chorioretinopathies (White Dot Syndromes), diagnosis and management: A review of the literatureBassey Fiebai, Safinatu Wada MohammedPort Harcourt Medical Journal 2019 13(1):1-6Background: The white dot syndromes or inflammatory chorioretinopathies are a heterogenous group of diseases of unknown aetiology, characterized by the appearance of white dots on the fundus. These group of disorders include, acute posterior multifocal placoid pigment epitheliopathy (APMPPE), serpiginous choroiditis,...
Appraisal of healthcare-seeking behavior and prevalence of workplace injury among artisans in automobile site in Abakaliki, Southeast NigeriaBenedict Ndubueze Azuogu, Nelson Chibueze Eze, Victoria Chioma Azuogu, Cosmas Kenan Onah, Edmund Ndudi Ossai, Adaoha Pearl AguNigerian Medical Journal 2018 59(5):45-49Background: Healthcare-seeking behavior is a decision-making process governed by an individual's conduct, community norms, and expectations, as well as provider-related characteristics and manners....
Qualitative assessment of cervical cancer awareness among primary health-care providers in Zaria, NigeriaAnisah Yahya, Aliyu Tambaya MandeNigerian Medical Journal 2018 59(5):50-54Background: Cervical cancer is a major cause of cancer morbidity and mortality, especially in the developing countries. Preventive measures have helped in curbing the morbidity and mortality associated with the disease in the developed countries. Primary health-care centers provide opportunity for the primary prevention...
Evaluation of the hearing test pro application as a screening tool for hearing loss assessmentShuaib Kayode AremuNigerian Medical Journal 2018 59(5):55-58Background: Disabling hearing loss is considered a significant health problem globally with high incidence in developing countries. In Africa, different studies have shown that one in five Africans uses smartphones. This dispositive can be used to screen hearing loss. Aim: The study aims to appraise the effectiveness of Hearing Test Pro, an Android-based...
Radiation-induced Amplification of TGFB1-induced Mesenchymal Stem Cell-mediated Sodium Iodide Symporter (NIS) Gene 131 I TherapyClinical Cancer Research Online First Ar.. by Schug, C., Kitzberger, C., Sievert,.. - 33m ago Preview AUTO POST SAVE TO EVERNOTEPurpose: The innate tumor homing potential of mesenchymal stem cells (MSC) has been used for a targeted delivery of the theranostic sodium iodide symporter (NIS) transgene into solid tumors. We have previously shown that external beam radiation...
Loss of ARID1A in tumor cells renders selective vulnerability to combined ionizing radiation and PARP inhibitor therapyClinical Cancer Research Online First Ar.. by Park, Y., Chui, M. H., Suryo Rahman.. - 33m ago Preview AUTO POST SAVE TO EVERNOTEPurpose: Somatic inactivating mutations in ARID1A, a component of the SWI/SNF chromatin remodeling complex, are detected in various types of human malignancies. Loss of ARID1A compromises DNA damage repairs, and induced DNA damage burdens may increase...
Auranofin Protects Intestine against Radiation Injury by Modulating p53/p21 Pathway and Radiosensitizes Human Colon TumorClinical Cancer Research Online First Ar.. by Nag, D., Bhanja, P., Riha, R., Sanc.. - 33m ago Preview AUTO POST SAVE TO EVERNOTEPurpose: The radiosensitivity of the normal intestinal epithelium is the major limiting factor for definitive radiotherapy against abdominal malignancies. Radiosensitizers, which can be used without augmenting radiation toxicity to normal tissue, are...
Polo-like Kinase 1 Inhibition as a Therapeutic Approach to Selectively Target BRCA1-Deficient Cancer Cells by Synthetic Lethality InductionClinical Cancer Research Online First Ar.. by Carbajosa, S., Pansa, M. F., Paviol.. - 33m ago Preview AUTO POST SAVE TO EVERNOTEPurpose: BRCA1 and BRCA2 deficiencies are widespread drivers of human cancers that await the development of targeted therapies. We aimed to identify novel synthetic lethal relationships with therapeutic potential using BRCA-deficient...
Macroevolutionary effects on primate trophic evolution and their implications for reconstructing primate originsPublication date: August 2019Source: Journal of Human Evolution, Volume 133Author(s): Jeremiah E. ScottAbstractThe visual-predation hypothesis proposes that certain derived features shared by crown primates reflect an insectivorous ancestry. Critics of this idea have argued that because insectivory is uncommon among extant primates it is unlikely to have been a major influence on early...
Clinical and microbiological effects of multiple applications of antibacterial photodynamic therapy in periodontal maintenance patients. A randomized controlled clinical studyPublication date: September 2019Source: Photodiagnosis and Photodynamic Therapy, Volume 27Author(s): K. Grzech-Leśniak, B. Gaspirc, A. SculeanAbstractBackgroundAt present, very limited data are available on the clinical and microbiological outcomes obtained following repeated application of aPDT following one single mechanical...
Advantages and disadvantages of implant navigation surgery. A systematic reviewPublication date: September 2019Source: Annals of Anatomy - Anatomischer Anzeiger, Volume 225Author(s): Jordi Gargallo-Albiol, Shayan Barootchi, Oscar Salomó-Coll, Hom-lay WangAbstractThis review elucidates the advantages and disadvantages of the different implant navigation methods to assist the precise surgical placement of dental implants. Implant navigation surgery can be classified into: dynamic and static navigation,...
The neglected aspect of applied biomaterials in medicine!Mahdi EbrahimiAnnals of Maxillofacial Surgery 2019 9(1):1-2Evidence-based maxillofacial surgerySM BalajiAnnals of Maxillofacial Surgery 2019 9(1):3-3Orthopantomography and cone-beam computed tomography for the relation of inferior alveolar nerve to the impacted mandibular third molarsNirmalendu Saha, NS Kedarnath, Madhumati SinghAnnals of Maxillofacial Surgery 2019 9(1):4-9Context: Relation of inferior alveolar nerve to the impacted mandibular...
Cocaine Abuse: An Attack to the Cardiovascular System—Insights from Cardiovascular MRIGianluca De Rubeis, Federica Catapano, Giulia Cundari, Andrea Ascione, Nicola Galea, Carlo Catalano, Marco Francone Author AffiliationsFrom the Department of Radiological, Oncological and Anatomopathological Sciences, Sapienza University of Rome, Viale Regina Elena 324, 00161 Rome, Italy.Address correspondence to M.F. (e-mail: marco.francone@uniroma1.it).Published Online:Jun 13 2019https://doi.org/10.1148/ryct.2019180031SectionsPDFToolsShareAbstractCocaine...
Comment & ResponseIncidence of Thyroid Cancer Among Children and Young Adults in Fukushima, JapanKazuyo Suzuki, MD, PhD; Hiroshi Toki, PhD; Takahiro Wada, PhDAbstract Full TextJAMA Otolaryngol Head Neck Surg. Published online June 13, 2019. doi:10.1001/jamaoto.2019.1099Invited CommentaryWhy the Data From the Fukushima Health Management Survey After the Daiichi Nuclear Power Station Accident Are ImportantAndrew J. Bauer, MD; Louise Davies, MD, MSIncidence of Thyroid Cancer Among Children and Young...
Massive Scalp Cylindromas Treated With Staged Resection and Split-Thickness Skin GraftingA. Eliot Shearer, MD, PhD1; Aditi Vidholia, MD2; Christopher S Jensen, MD2; et al Rodrigo Bayon, MD1Author Affiliations1Department of Otolaryngology–Head and Neck Surgery, University of Iowa Carver College of Medicine, Iowa City2Department of Pathology, University of Iowa Carver College of Medicine, Iowa CityJAMA Otolaryngol Head Neck Surg. Published online June 13, 2019. doi:10.1001/jamaoto.2019.1234FullTextA...
Characterization of Malignant Head and Neck Paragangliomas at a Single Institution Across Multiple DecadesHilary C. McCrary, MD, MPH1; Eric Babajanian, MD1; Matias Calquin, BS2; et al Patrick Carpenter, MD1; Geoffrey Casazza, MD1; Anne Naumer, MS3; Samantha Greenberg, MS, MPH3; Wendy Kohlmann, MS3; Richard Cannon, MD1; Marcus M. Monroe, MD1; Jason P. Hunt, MD1; Luke Buchmann, MD1Author AffiliationsJAMA Otolaryngol Head Neck Surg. Published online June 13, 2019. doi:10.1001/jamaoto.2019.1110Key PointsQuestion ...
Low Awareness of Scammers' Tactics Linked to Dementia Risk in Cognitively Normal PeopleRita Rubin, MAJAMA. Published online June 12, 2019. doi:10.1001/jama.2019.5765multimedia icon MultimediaAudio (17:29)Low Awareness of Scammers' Tactics Linked to Dementia Risk in Cognitively Normal PeopleStudies have shown that susceptibility to scams, such as fake IRS agents who demand payment of back taxes or a fake lottery that requires money up front before distributing winnings, has been associated with progression...
Primary Prevention of Sudden Cardiac DeathAndrew D. Beaser, MD1; Adam S. Cifu, MD1; Hemal M. Nayak, MD1Author Affiliations Article InformationJAMA. Published online June 13, 2019. doi:10.1001/jama.2019.7662Guideline title 2017 AHA/ACC/HRS Guideline for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac DeathRelease date September 25, 2018Prior versions 2008 ACC/AHA/HRS Guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities (specifically sections...
Characterization of Malignant Head and Neck Paragangliomas at a Single Institution Across Multiple DecadesHilary C. McCrary, MD, MPH1; Eric Babajanian, MD1; Matias Calquin, BS2; et al Patrick Carpenter, MD1; Geoffrey Casazza, MD1; Anne Naumer, MS3; Samantha Greenberg, MS, MPH3; Wendy Kohlmann, MS3; Richard Cannon, MD1; Marcus M. Monroe, MD1; Jason P. Hunt, MD1; Luke Buchmann, MD1Author Affiliations Article InformationJAMA Otolaryngol Head Neck Surg. Published online June 13, 2019. doi:10.1001/jamaoto.2019.1110Key...
Accuracy and reliability of enamel and dentin thickness measurements on micro-computed tomography and digital periapical radiographs#Publication date: Available online 4 June 2019Source: Journal of Forensic Radiology and ImagingAuthor(s): Ceren Aktuna Belgın, Gozde Serindere, Kaan OrhanAbstractIn the application of scientific human skeletal variation in medico-legal matters, virtual anthropology is the current technique performed to examine skeleton and its body parts. Digital imaging techniques...
Alexandros Sfakianakis
Anapafseos 5 . Agios Nikolaos
Crete.Greece.72100
2841026182
Anapafseos 5 . Agios Nikolaos
Crete.Greece.72100
2841026182
6948891480
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