• Repurposing approved drugs on the pathway to novel therapies.

  Related ArticlesRepurposing approved drugs on the pathway to novel therapies. Med Res Rev. 2019 Aug 20;: Authors: Schein CH Abstract The time and cost of developing new drugs have led many groups to limit their search for therapeutics to compounds that have previously been approved for human use. Many "repurposed" drugs, such as derivatives of thalidomide, antibiotics, and antivirals have had clinica

  !@ Rare Cancers

  Thu Aug 22, 2019 06:21
• Metachronous or synchronous male breast and prostate cancers a duality to lookout for.

  Related ArticlesMetachronous or synchronous male breast and prostate cancers a duality to lookout for. F1000Res. 2018;7:1825 Authors: Mukendi AM, Van Den Berg E, Pather S, Padayachee RS Abstract Introduction: Breast cancer is well known as the stereotypical women's cancer, and prostate cancer represents the well-known stereotypical male counterpart. While prostate cancer carries the potential to meta

  !@ Rare Cancers

  Thu Aug 22, 2019 06:21
• Incidence and patterns of retropharyngeal lymph node involvement in oropharyngeal carcinoma.

  Related ArticlesIncidence and patterns of retropharyngeal lymph node involvement in oropharyngeal carcinoma. Radiother Oncol. 2019 Aug 17;: Authors: Iyizoba-Ebozue Z, Murray LJ, Arunsingh M, Vaidyanathan S, Scarsbrook AF, Prestwich RJD Abstract INTRODUCTION: The aim was to evaluate in oropharyngeal carcinoma the: (1) incidence and predictors of retropharyngeal (RP) lymph node (LN) involvement, (2) pa

  !@ Rare Cancers

  Thu Aug 22, 2019 06:21
• Surgical treatment of intraperitoneal metastases from lung cancer: two case reports and a review of the literature.

  Related ArticlesSurgical treatment of intraperitoneal metastases from lung cancer: two case reports and a review of the literature. J Med Case Rep. 2019 Aug 21;13(1):262 Authors: Sibio S, Sica GS, Di Carlo S, Cardi M, Di Giorgio A, Sollazzo BM, Sammartino P Abstract BACKGROUND: Peritoneal metastases are often reported in several abdominal tumors. Peritoneal diffusion from extra-abdominal tumors is th

  !@ Rare Cancers

  Thu Aug 22, 2019 06:21
• [Recurrent ataxia and respiratory failure with probable paraneoplastic syndrome responsive to plasma exchange therapy].

  Related Articles[Recurrent ataxia and respiratory failure with probable paraneoplastic syndrome responsive to plasma exchange therapy]. Rinsho Shinkeigaku. 2019 Jun 22;59(6):339-344 Authors: Kondo T, Igari R, Sato H, Iseki C, Ishizawa K, Suzuki K Abstract An 80-year-old male with prostatic adenocarcinoma who was treated with orchiectomy presented dysarthria and difficulty in walking. His symptoms s

  !@ Rare Cancers

  Thu Aug 22, 2019 06:21
• Bilateral pseudocyst of the auricles in a 4-week neonate-case report and world literature review.

  Related ArticlesBilateral pseudocyst of the auricles in a 4-week neonate-case report and world literature review. Int J Pediatr Otorhinolaryngol. 2019 Jul;122:1-5 Authors: Dutsch-Wicherek M, Trzebuniak I, Szymońska I, Młynarski D, Kobos J, Wicherek Ł, Kwinta P Abstract Pseudocyst of the auricle is a rare, idiopathic disease clinically manifesting as a painless edema of the upper-late

  !@ Rare Cancers

  Thu Aug 22, 2019 06:21
• Transudative myelomatous pleurisy revealing pleural localization of primary plasma cell leukemia.

  Related ArticlesTransudative myelomatous pleurisy revealing pleural localization of primary plasma cell leukemia. Ann Biol Clin (Paris). 2019 Apr 01;77(2):187-190 Authors: Bouayadi O, Id M'barek A, Lyagoubi A, Taghlaoui R, Aarab A, Kouismi H, Seddik R Abstract Primary plasma cell leukemia (PPCL) is an aggressive and rare variant of multiple myeloma (MM), with frequent extramedullary involvement, ma

  !@ Rare Cancers

  Thu Aug 22, 2019 06:21
• Urachal cancer-current concepts of a rare cancer.

  Related ArticlesUrachal cancer-current concepts of a rare cancer. Pathologe. 2019 Jun;40(Suppl 1):31-39 Authors: Reis H, Szarvas T Abstract Urachal cancer is a rare but aggressive disease. In addition to the non-glandular tumors, non-cystic urachal adenocarcinomas are nowadays distinguished from the primary cystic variant. (Immunohistochemical) markers are only of minor differential diagn

  !@ Rare Cancers

  Thu Aug 22, 2019 06:21
• Gallbladder carcinoma. Surgical management of gallblad-der carcinoma. An analysis of 37 cases.

  Related ArticlesGallbladder carcinoma. Surgical management of gallblad-der carcinoma. An analysis of 37 cases. Ann Ital Chir. 2018;89:501-506 Authors: Graur F, Mois E, Margarit S, Hagiu C, Al Hajjar N Abstract BACKGROUND & AIMS: Gallbladder carcinoma is a rare yet very aggressive cancer. In this study we evaluate the presentation, staging, procedures, complications and survival of patients with g

  !@ Rare Cancers

  Thu Aug 22, 2019 06:21
• DNA damage repair alterations are frequent in prostatic adenocarcinomas with focal pleomorphic giant-cell features.

  Related ArticlesDNA damage repair alterations are frequent in prostatic adenocarcinomas with focal pleomorphic giant-cell features. Histopathology. 2019 May;74(6):836-843 Authors: Lotan TL, Kaur HB, Alharbi AM, Pritchard CC, Epstein JI Abstract AIMS: Prostatic adenocarcinomas with focal pleomorphic giant-cell features constitute a rare tumour subtype with abysmal clinical outcomes. More than one-th

  !@ Rare Cancers

  Thu Aug 22, 2019 06:21
• ALK and EGFR expression by immunohistochemistry are associated with Merkel cell polyomavirus status in Merkel cell carcinoma.

  Related ArticlesALK and EGFR expression by immunohistochemistry are associated with Merkel cell polyomavirus status in Merkel cell carcinoma. Histopathology. 2019 May;74(6):829-835 Authors: Veija T, Kero M, Koljonen V, Böhling T Abstract AIMS: Merkel cell carcinoma, a rare cutaneous neuroendocrine tumour of the skin, can be categorised into two groups according to Merkel cell polyomavirus (MCV

  !@ Rare Cancers

  Thu Aug 22, 2019 06:21
• Maxillary Sinus Mass as First Presentation of Silent Metastatic Renal Cell Carcinoma.

  Related ArticlesMaxillary Sinus Mass as First Presentation of Silent Metastatic Renal Cell Carcinoma. J Craniofac Surg. 2019 Mar/Apr;30(2):e135-e137 Authors: Moffa A, Casale M, Moffa AP, Grilli G, Grilli G, Macarini L, Cassano M Abstract Renal cell carcinoma accounts for more than 3% of all malignant diseases. Metastatic disease to the head and neck ranges from 15% to 30%. The 5-year survival rate

  !@ Rare Cancers

  Thu Aug 22, 2019 06:21
• Inferior survival for patients with malignant peripheral nerve sheath tumors defined by aberrant TP53.

  Related ArticlesInferior survival for patients with malignant peripheral nerve sheath tumors defined by aberrant TP53. Mod Pathol. 2018 11;31(11):1694-1707 Authors: Høland M, Kolberg M, Danielsen SA, Bjerkehagen B, Eilertsen IA, Hektoen M, Mandahl N, van den Berg E, Smeland S, Mertens F, Sundby Hall K, Picci P, Sveen A, Lothe RA Abstract Malignant peripheral nerve sheath tumor is a rare and

  !@ Rare Cancers

  Thu Aug 22, 2019 06:21
• Clinicopathological description of 43 oncocytic adrenocortical tumors: importance of Ki-67 in histoprognostic evaluation.

  Related ArticlesClinicopathological description of 43 oncocytic adrenocortical tumors: importance of Ki-67 in histoprognostic evaluation. Mod Pathol. 2018 11;31(11):1708-1716 Authors: Renaudin K, Smati S, Wargny M, Al Ghuzlan A, Aubert S, Leteurtre E, Patey M, Sibony M, Sturm N, Tissier F, Amar L, Bertherat J, Berthozat C, Chabre O, Do Cao C, Haissaguerre M, Pierre P, Briet C, Vezzosi D, Lifante JC, Pattou F, Mirall

  !@ Rare Cancers

  Thu Aug 22, 2019 06:21
• Treatment Approaches and Outcomes for Primary Mediastinal Sarcoma: Analysis of 976 Patients.

  Related ArticlesTreatment Approaches and Outcomes for Primary Mediastinal Sarcoma: Analysis of 976 Patients. Ann Thorac Surg. 2018 08;106(2):333-339 Authors: Engelhardt KE, DeCamp MM, Yang AD, Bilimoria KY, Odell DD Abstract BACKGROUND: Primary mediastinal sarcomas are rare and deadly. Our objective was to describe the clinicopathological features, treatment strategies, and overall survival outcome

  !@ Rare Cancers

  Thu Aug 22, 2019 06:21
• Prothrombin complex concentrate and fatal thrombotic adverse events: A complication to keep in mind.

  Related ArticlesProthrombin complex concentrate and fatal thrombotic adverse events: A complication to keep in mind. Drug Discov Ther. 2018 May 13;12(2):104-107 Authors: Tabet R, Shammaa Y, Karam B, Yacoub H, Lafferty J Abstract Thromboembolic events such as deep vein thrombosis and pulmonary embolism are well-known complications that can occur after prothrombin complex concentrate therapy. However

  !@ Rare Cancers

  Thu Aug 22, 2019 06:21
• Venous Malformation of the Esophagus.

  Related ArticlesVenous Malformation of the Esophagus. Ann Thorac Surg. 2018 08;106(2):e69-e71 Authors: Cano Busnelli V, Medici J, Duro A, Castellaro P, Wright F, Cavadas D, Beskow A Abstract Venous malformations are an extremely infrequent condition in the gastrointestinal tract, particularly in the esophagus. We report a rare case of an adult with an asymptomatic mass located in the medi

  !@ Rare Cancers

  Thu Aug 22, 2019 06:21
• Giant Cell Tumor of Bone Presenting as Left Posteromedial Chest Wall Tumor.

  Related ArticlesGiant Cell Tumor of Bone Presenting as Left Posteromedial Chest Wall Tumor. Ann Thorac Surg. 2018 08;106(2):e89-e91 Authors: Nasser H, Dhanekula A, Abdulhak M, Mott M, Hammoud ZT Abstract Giant cell tumor is a relatively uncommon bone tumor rarely originating from the chest wall. Given its proximity to vital structures in the thoracic cavity, treatment options may be challenging. We

  !@ Rare Cancers

  Thu Aug 22, 2019 06:21
• Primary cutaneous peripheral T-cell lymphoma not otherwise specified a rare and aggressive lymphoma.

  Related ArticlesPrimary cutaneous peripheral T-cell lymphoma not otherwise specified a rare and aggressive lymphoma. J Eur Acad Dermatol Venereol. 2018 Oct;32(10):e373-e376 Authors: Pileri A, Agostinelli C, Fuligni F, Broccoli A, Gunnella S, Sabattini E, Grandi V, Guglielmo A, Zinzani PL, Patrizi A, Pimpinelli N PMID: 29573477 [PubMed - indexed for MEDLINE]

  !@ Rare Cancers

  Thu Aug 22, 2019 06:21
• Synchronous Presentation of Pheochromocytoma and Epidermoid Lung Carcinoma.

  Related ArticlesSynchronous Presentation of Pheochromocytoma and Epidermoid Lung Carcinoma. Ann Thorac Surg. 2018 08;106(2):e99 Authors: Gregory J, Bennani S, Freche G, Mansuet-Lupo A, Revel MP, Chassagnon G PMID: 29551630 [PubMed - indexed for MEDLINE]

  !@ Rare Cancers

  Thu Aug 22, 2019 06:21
• Verrucous carcinoma of the esophagus: A rare entity with a difficult diagnosis.

  Related ArticlesVerrucous carcinoma of the esophagus: A rare entity with a difficult diagnosis. Cir Esp. 2018 Aug - Sep;96(7):453-455 Authors: Paseiro Crespo G, Nebreda MG, Barceló López M, Marqués Medina E, Gimeno Aranguez M PMID: 29452967 [PubMed - indexed for MEDLINE]

  !@ Rare Cancers

  Thu Aug 22, 2019 06:21
• [Vascular Cutaneous Abnormalities in Togo: a 120-Case Study].

  Related Articles[Vascular Cutaneous Abnormalities in Togo: a 120-Case Study]. Bull Soc Pathol Exot. 2018;111(5):278-282 Authors: Akakpo AS, Saka B, Téclessou JN, Djalogue L, Mahamadou G, Mouhari-Touré A, Gottara WS, Kombaté K, Tchangai-Walla K, Pitché P Abstract The purpose of this study was to describe the epidemio-clinical profile, and treatment of vascular cutaneous abnormalities in Togo. It was a

  !@ Rare Cancers

  Thu Aug 22, 2019 06:21
• A Retrospective Multicentric Study of Ewing Sarcoma Family of Tumors in Patients Older Than 50: Management and Outcome.

  Related ArticlesA Retrospective Multicentric Study of Ewing Sarcoma Family of Tumors in Patients Older Than 50: Management and Outcome. Sci Rep. 2017 12 20;7(1):17917 Authors: Rochefort P, Italiano A, Laurence V, Penel N, Lardy-Cleaud A, Mir O, Chevreau C, Bertucci F, Bompas E, Chaigneau L, Levy D, Ryckewaert T, Dumont S, Meeus P, Ranchere D, Blay JY, Cassier PA Abstract Ewing's sarcoma family of

  !@ Rare Cancers

  Thu Aug 22, 2019 06:21
• Quantifying the effects of data augmentation and stain color normalization in convolutional neural networks for computational pathology

  Publication date: Available online 21 August 2019Source: Medical Image AnalysisAuthor(s): David Tellez, Geert Litjens, Péter Bándi, Wouter Bulten, John-Melle Bokhorst, Francesco Ciompi, Jeroen van der LaakAbstractStain variation is a phenomenon observed when distinct pathology laboratories stain tissue slides that exhibit similar but not identical color appearance. Due to this color shift between laboratories, convolutional neural

  Medical Image Analysis

  Thu Aug 22, 2019 06:20
• ALCOHOL; +66 new citations

  66 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: ALCOHOL These pubmed results were generated on 2019/08/22PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.

  Alcohol

  Thu Aug 22, 2019 06:19
• Duration of use of proton pump inhibitors and the risk of gastric and oesophageal cancer

  Publication date: October 2019Source: Cancer Epidemiology, Volume 62Author(s): Nele Brusselaers, Jesper Lagergren, Lars EngstrandAbstractBackgroundThere is increasing interest in the potential association between proton pump inhibitors (PPIs) and the risk of gastric and oesophageal cancer, yet the effect of duration of treatment needs clarification.MethodsThis Swedish population-based cohort study assessed the influence of time since initiation o

  ScienceDirect Publication: Cancer Epidemiology (open access)

  Thu Aug 22, 2019 06:08
• Molecularly imprinted polymer modified glassy carbon electrodes for the electrochemical analysis of isoproturon in water

  Publication date: 15 January 2020Source: Talanta, Volume 207Author(s): Imer Sadriu, Sarra Bouden, Jimmy Nicolle, Fetah I. Podvorica, Valérie Bertagna, Catherine Berho, Laurence Amalric, Christine Vautrin-UlAbstractIsoproturon-imprinted polypyrrole films were electrochemically synthesized onto glassy carbon (GC) electrodes in an ethanol/aqueous solution of pyrrole as a monomer, isoproturon as a template molecule and LiClO4 as supporting el

  ScienceDirect Publication: Talanta

  Thu Aug 22, 2019 06:03
• Efficient separation of tumor cells from untreated whole blood using a novel multistage hydrodynamic focusing microfluidics

  Publication date: 15 January 2020Source: Talanta, Volume 207Author(s): Rongke Gao, Lei Cheng, Shiyi Wang, Xiaobai Bi, Xueli Wang, Rui Wang, Xinyu Chen, Zhengbao Zha, Feng Wang, Xiaofeng Xu, Gang Zhao, Liandong YuAbstractSignificant progress on circulating tumor cells (CTCs) has profound impact for noninvasive tumor profiling including early diagnosis, treatment monitoring, and metastasis recognition. Therefore, CTCs based liquid biopsy technolog

  ScienceDirect Publication: Talanta

  Thu Aug 22, 2019 06:03
• A spatial-confinement hairpin cascade reaction-based DNA tetrahedral amplifier for mRNA imaging in live cells

  Publication date: Available online 22 August 2019Source: TalantaAuthor(s): Manman He, Mengyun He, Juan Zhang, Chang Liu, Qingshan Pan, Jintao Yi, Tingting ChenAbstractThe three-dimensional (3D) DNA nanostructure has been got much attention due to its excellent biocompatibility, enhanced structural stability, highly programmable and perfect cell-delivery performance. Here, a novel 3D DNA tetrahedron amplifier (DTA) has been developed for rapid an

  ScienceDirect Publication: Talanta

  Thu Aug 22, 2019 06:03
• Fluorescence resonance energy transfer between NH₂–NaYF₄:Yb,Er/NaYF₄@SiO₂ upconversion nanoparticles and gold nanoparticles for the detection of glutathione and cadmium ions

  Publication date: Available online 21 August 2019Source: TalantaAuthor(s): Leilei Sun, Tao Wang, Yuzhen Sun, Zexin Li, Haining Song, Bin Zhang, Guangjun Zhou, Haifeng Zhou, Jifan HuAbstractDual-functional nanosensors based on small molecule regulation can be widely used due to their simplicity, high sensitivity and selectivity. Herein, glutathione (GSH) calibrated dual-functional system for GSH and cadmium ions (Cd2+) detection based on fluoresc

  ScienceDirect Publication: Talanta

  Thu Aug 22, 2019 06:03
• A rapid sequential chromatographic separation of U- and Th-decay series radionuclides in water samples

  Publication date: Available online 21 August 2019Source: TalantaAuthor(s): Claire Dalencourt, Mohamed Nait Chabane, Jean-Christophe Tremblay-Cantin, Dominic LarivièreAbstractA new sequential protocol for the separation and preconcentration of U, Th, Ra, Po and Pb for the same sample aliquot has been designed. The optimized stacking of chromatographic resins, [TRU, Sr and a new hybrid Ra resin (composed of Analig Ra-01 and cation exchange

  ScienceDirect Publication: Talanta

  Thu Aug 22, 2019 06:03
• Corrigendum to “Renoprotective Effects of Aldose Reductase Inhibitor Epalrestat against High Glucose-Induced Cellular Injury”

  BioMed Research International

  Thu Aug 22, 2019 05:05
• לזכרו של ישראל בן־דוד

  כ"א בכסלו תרפ"ה – י"ט באב תשע"ט | 18 בדצמבר 1924 – 20 באוגוסט 2019 בי"ט באב, 20 באוגוסט, הלך לעולמו ח

  האקדמיה ללשון העברית

  Thu Aug 22, 2019 05:04
• חוזרים לבית הספר

  The post חוזרים לבית הספר appeared first on האקדמיה ללשון העברית.

  האקדמיה ללשון העברית

  Thu Aug 22, 2019 04:54
• Carcinoma ex pleomorphic adenoma: A review of incidence, demographics, risk factors, and survival

  Publication date: Available online 21 August 2019Source: American Journal of OtolaryngologyAuthor(s): Avigeet Gupta, Sina Koochakzadeh, David M. Neskey, Shaun A. Nguyen, Eric J. LentschAbstractPurposeIdentify variables that are independent predictors of survival in carcinoma ex pleomorphic adenoma (CXPA) of the major salivary glands using a population-based database and evaluate the incidence and management strategies for this rare malignancy.Ma

  American Journal of Otolaryngology

  Thu Aug 22, 2019 05:35
• Pembrolizumab in lung cancer: current evidence and future perspectives. Pembrolizumab in lung...

  Pembrolizumab in lung cancer: current evidence and future perspectives.Pembrolizumab in lung cancer: current evidence and future perspectives. Future Oncol. 2019 Aug 21;: Authors: Palumbo G, Carillio G, Manzo A, Montanino A, Sforza V, Costanzo R, Sandomenico C, Manna C, Luca G, Piccirillo MC, Daniele G, Cecio R, Botti G, Totaro G, Muto P, Picone C, Esposito G, Normanno N, Morabito A Abstract Pembrolizumab is a humanized monoclonal anti

  Αλέξανδρος Γ. Σφακιανάκης

  Thu Aug 22, 2019 23:02
• Can the Jankovic-assessment be used as an alternative to electromyography? A cross-sectional study on facial dystonia patients treated with Botulinum toxin

  Publication date: Available online 21 August 2019Source: American Journal of OtolaryngologyAuthor(s): Di Stadio Arianna, Dipietro Laura, Gambacorta Valeria, Cristi Maria Cristina, Mario Faralli, Antonio della Volpe, Ricci GiampietroAbstractPurposeThis study aims to quantitatively compare the Jankovic assessment (JA) with electromyography (EMG)-based measures for assessing changes in facial movements in patients with facial dystonia.Materials and

  American Journal of Otolaryngology

  Thu Aug 22, 2019 05:35
• Parallel Evolution in the Emergence of Highly Pathogenic Avian Influenza A Viruses [NEW RESULTS]

  Parallel molecular evolution and adaptation are important phenomena commonly observed in viruses. Here we exploit parallel molecular evolution to understand virulence evolution in avian influenza viruses (AIV). Highly-pathogenic AIVs independently evolve from low-pathogenic ancestors via acquisition of a polybasic cleavage sites (pCS). Why some AIV lineages but not others evolve in this way is unknown. We hypothesise that the parallel emergence o

  bioRxiv Subject Collection: Evolutionary Biology

  Wed Aug 21, 2019 17:00
• Sintilimab to Prevent High-risk Oral Premalignant Lesions Cancerization

  Conditions:   Oral Cavity Cancer;   Mouth Neoplasm;   Precancerous ConditionsIntervention:   Drug: SintilimabSponsor:   Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong UniversityNot yet recruiting

  ClinicalTrials

  Thu Aug 22, 2019 05:32
• Individual Patient Expanded Access IND of Autologous HB-adMSC for Chronic Spinal Cord Injury With HB-adMSCs

  Condition:   Spinal Cord InjuriesIntervention:   Drug: HB-adMSCsSponsor:   Hope BiosciencesAvailable

  ClinicalTrials

  Thu Aug 22, 2019 05:32
• Intratumoral Microdosing of TAK-981 in Head and Neck Cancer

  Condition:   Head and Neck CancerIntervention:   Drug: TAK-981Sponsors:   Presage Biosciences;   TakedaNot yet recruiting

  ClinicalTrials

  Thu Aug 22, 2019 05:32
• FLASH radiotherapy International Workshop

  Publication date: Available online 21 August 2019Source: Radiotherapy and OncologyAuthor(s): Marie-Catherine Vozenin, Michael Baumann, Rob P. Coppes, Jean Bourhis

  Radiotherapy and Oncology

  Thu Aug 22, 2019 05:32
• Comparable radiation response of <em>ex vivo</em> and <em>in vivo</em> irradiated tumor samples determined by residual γH2AX

  Publication date: Available online 21 August 2019Source: Radiotherapy and OncologyAuthor(s): Treewut Rassamegevanon, Steffen Löck, Michael Baumann, Mechthild Krause, Cläre von NeubeckAbstractPurposea) To investigate if an ex vivo cultured and irradiated tumor biopsy reflects and predicts the radiation response of the corresponding in vivo irradiated tumor measured with the DNA double strand break marker γH2AX foci.Materials and m

  Radiotherapy and Oncology

  Thu Aug 22, 2019 05:32
• A single-blind, randomised controlled trial of StrataXRT® – A silicone-based film-forming gel dressing for prophylaxis and management of radiation dermatitis in patients with head and neck cancer

  Publication date: Available online 21 August 2019Source: Radiotherapy and OncologyAuthor(s): Raymond J. Chan, Rae Blades, Lee Jones, Tai-Rae Downer, Samuel C. Peet, Elise Button, David Wyld, Steven McPhail, Melissa Doolan, Patsy YatesAbstractAimInvestigate the effects of StrataXRT® versus 10% Glycerine (Sorbolene cream) for preventing and managing radiation dermatitis in patients with head and neck cancer receiving radical radiotherapy (≥

  Radiotherapy and Oncology

  Thu Aug 22, 2019 05:32
• Single vs multiple fraction palliative radiation therapy for bone metastases: Cumulative meta-analysis

  Publication date: Available online 21 August 2019Source: Radiotherapy and OncologyAuthor(s): Ronald Chow, Peter Hoskin, Steven E. Schild, Srinivas Raman, James Im, Daniel Zhang, Stephanie Chan, Nicholas Chiu, Leonard Chiu, Henry Lam, Edward Chow, Michael LockAbstractIntroductionThere has been a long-standing debate regarding the efficacy of single fraction radiotherapy (SFRT) compared to multiple fraction radiotherapy (MFRT); many systematic rev

  Radiotherapy and Oncology

  Thu Aug 22, 2019 05:32
• Expression patterns of natriuretic peptides in pre-hibernating and hibernating anatolian ground squirrel (<em>Spermophilus xanthoprymnus</em>) lung

  Publication date: Available online 22 August 2019Source: Acta HistochemicaAuthor(s): Mustafa Öztop, Mehmet Özbek, Narin Liman, Feyzullah Beyaz, Emel Ergün, Levent Ergün, Ural Kemal Kavraal, Ergül ErgenAbstractAnatolian ground squirrel (Spermophilus xanthoprymnus) is a true hibernator. This animal transiently reduces pulmonary function during hibernation. Continuance of pulmonary function is very important to survive grou

  Acta Histochemica

  Thu Aug 22, 2019 05:28
• Prognostic Significance of CIP2A in Esophagogastric Junction Adenocarcinoma: A Study of 65 Patients and a Meta-Analysis

  Background. The expression of the cancerous inhibitor protein phosphatase 2A (CIP2A) appears to be predictive of the prognosis of various solid tumors. However, the association between this protein and the risk of esophagogastric junction adenocarcinoma (EGJA) remains unclear. We investigated CIP2A expression and its clinical significance in EGJA and conducted a meta-analysis to explore the relationship between CIP2A and the prognosis of patients

  Disease Markers

  Thu Aug 22, 2019 04:05
• Human Epididymis Protein 4 (HE4) Reference Limits in Polish Population of Healthy Women, Pregnant Women, and Women with Benign Ovarian Tumors

  Objectives. Defining precisely the normal range of HE4 protein is crucial for the proper interpretation of tumor marker results and for a more efficient diagnosis of ovarian malignancy. The aim of our study was to evaluate a reference limit of HE4 protein in a population to promote and facilitate the common use of HE4 protein assays. We also tried to identify potential association of HE4 levels with other conditions such as smoking, age, BMI, and

  Disease Markers

  Thu Aug 22, 2019 04:05
• ΠΟΥ: Τα μικροπλαστικά σωματίδια στο νερό δεν είναι επικίνδυνα για την υγεία

  Τα πλαστικά μικροσωματίδια (διαστάσεων μικρότερων των (5 mm) που καταπίνουμε μέσω της τροφής, του νερού και της αναπνοής, τελικά δεν φαίνεται να ενέχουν κινδύνους για την υγεία μας, αποφαίνεται ο Παγκόσμιος Οργανισμός Υγείας (ΠΟΥ), μετά τον σάλο που προκάλεσε πρόσφατη καναδική μελέτη. Συγκεκριμένα, έρευνα που δημοσιεύθηκε στο Environmental Science and Technology, υποστήριζε ότι ο μέσος ενήλικας καταπίνει και εισπνέει 74.000 έως 121.000 μικροσκοπ

  Επιστημονικές Εξελίξεις – ygeiamou | Το αξιόπιστο site για την Υγεία, τη Διατροφή και την Ευεξία

  Thu Aug 22, 2019 03:07
• Ωμέγα-3 λιπαρά οξέα: Να πάρω ή όχι;

  Τα άτομα με διαβήτη τύπου 2 «δεν θα πρέπει να ενθαρρύνονται» να παίρνουν συμπληρώματα ιχθυελαίου πλούσιου σε ωμέγα-3 λιπαρά οξέα, υποστηρίζουν ερευνητές από το Πανεπιστήμιο της Ανατολικής Αγγλίας. Κατά καιρούς έχουν διατυπωθεί ανησυχίες σχετικά με την επίδραση των ωμέγα-3 στα άτομα με σακχαρώδη διαβήτη τύπου 2. Οι ερευνητές στην ανασκόπηση που δημοσιεύουν στο BMJ εξέτασαν δεδομένα πάνω από 80 ήδη δημοσιευμένες μελέτες και απέτυχαν να βρουν κάπο

  Επιστημονικές Εξελίξεις – ygeiamou | Το αξιόπιστο site για την Υγεία, τη Διατροφή και την Ευεξία

  Thu Aug 22, 2019 02:11
• Training simulation for oral and maxillofacial surgeons based on the techniques of arthroscopy in the temporomandibular joint

  Publication date: Available online 22 August 2019Source: British Journal of Oral and Maxillofacial SurgeryAuthor(s): P. Peserico-DalFarra, A.F. Gagliardi-LugoAbstractArthroscopy is a diagnostic-therapeutic technique used in the treatment of disorders of the temporomandibular joint (TMJ). The difficulties of arthroscopy lie in the manipulation of the tools, which is why training in the technique of triangulation in artificial models is essential.

  British Journal of Oral and Maxillofacial Surgery

  Thu Aug 22, 2019 05:19
• Discriminating association of a common telomerase reverse transcriptase promoter polymorphism with telomere parameters in non-small cell lung cancer with or without epidermal growth factor receptor mutation

  Publication date: October 2019Source: European Journal of Cancer, Volume 120Author(s): Ping Yuan, Sha Huang, Fei-Chao Bao, Jin-Lin Cao, Hong-Xu Sheng, Liang Shi, Wang Lv, Jian HuAbstractBackgroundThe role of epidermal growth factor receptor (EGFR) pathways in regulating telomerase is increasingly being recognised. We analysed the impact of rs2853669 single nucleotide polymorphism (SNP) on telomere parameters and its prognostic value for non-small

  European Journal of Cancer

  Thu Aug 22, 2019 05:04
• Three-year follow-up from a phase 3 study of SB3 (a trastuzumab biosimilar) versus reference trastuzumab in the neoadjuvant setting for human epidermal growth factor receptor 2–positive breast cancer

  Publication date: October 2019Source: European Journal of Cancer, Volume 120Author(s): Xavier Pivot, Mark Pegram, Javier Cortes, Diana Lüftner, Gary H. Lyman, Giuseppe Curigliano, Igor Bondarenko, Ye Chan Yoon, Younsoo Kim, Chul KimAbstractBackgroundWe assessed long-term cardiac safety and efficacy in patients with human epidermal growth factor receptor 2–positive early breast cancer treated with a trastuzumab biosimilar (SB3) or its reference pr

  European Journal of Cancer

  Thu Aug 22, 2019 05:04
• Safety and efficacy of nivolumab in patients with rare melanoma subtypes who progressed on or after ipilimumab treatment: a single-arm, open-label, phase II study (CheckMate 172)

  Publication date: September 2019Source: European Journal of Cancer, Volume 119Author(s): Paul Nathan, Paolo A. Ascierto, John Haanen, Enrique Espinosa, Lev Demidov, Claus Garbe, Michele Guida, Paul Lorigan, Vanna Chiarion-Sileni, Helen Gogas, Michele Maio, Maria Teresa Fierro, Christoph Hoeller, Patrick Terheyden, Ralf Gutzmer, Tormod K. Guren, Dimitrios Bafaloukos, Piotr Rutkowski, Ruth Plummer, Ashita WaterstonAbstractBackgroundNivolumab has be

  European Journal of Cancer

  Thu Aug 22, 2019 05:04
• Retracted: Treatment of Acute Pulmonary Embolism: Update on Newer Pharmacologic and Interventional Strategies

  BioMed Research International

  Thu Aug 22, 2019 04:05
• Cancers, Vol. 11, Pages 1227: The Changing Therapeutic Landscape of Metastatic Renal Cancer

  Cancers, Vol. 11, Pages 1227: The Changing Therapeutic Landscape of Metastatic Renal Cancer Cancers doi: 10.3390/cancers11091227 Authors: Javier C. Angulo Oleg Shapiro The practising clinician treating a patient with metastatic clear cell renal cell carcinoma (CCRCC) faces a difficult task of choosing the most appropriate therapeutic regimen in a rapidly developing field with recommendations derived from clinical trials. NCCN guid

  Cancers

  Wed Aug 21, 2019 17:00
• Cancers, Vol. 11, Pages 1226: A Mouse Model to Assess STAT3 and STAT5A/B Combined Inhibition in Health and Disease Conditions

  Cancers, Vol. 11, Pages 1226: A Mouse Model to Assess STAT3 and STAT5A/B Combined Inhibition in Health and Disease Conditions Cancers doi: 10.3390/cancers11091226 Authors: Herwig P. Moll Julian Mohrherr Leander Blaas Monica Musteanu Patricia Stiedl Beatrice Grabner Katalin Zboray Margit König Dagmar Stoiber Thomas Rülicke Sabine Strehl Robert Eferl Emilio Casanova Genetically-engineered mouse model

  Cancers

  Wed Aug 21, 2019 17:00
• Cancers, Vol. 11, Pages 1228: Keratin-14 (KRT14) Positive Leader Cells Mediate Mesothelial Clearance and Invasion by Ovarian Cancer Cells

  Cancers, Vol. 11, Pages 1228: Keratin-14 (KRT14) Positive Leader Cells Mediate Mesothelial Clearance and Invasion by Ovarian Cancer Cells Cancers doi: 10.3390/cancers11091228 Authors: Maree Bilandzic Adam Rainczuk Emma Green Nicole Fairweather Thomas W. Jobling Magdalena Plebanski Andrew N. Stephens Epithelial ovarian cancer metastasis is driven by spheroids, which are heterogeneous cancer cell aggregates released f

  Cancers

  Wed Aug 21, 2019 17:00
• Pseudogene Associated Recurrent Gene Fusion in Prostate Cancer

  Publication date: October 2019Source: Neoplasia, Volume 21, Issue 10Author(s): Balabhadrapatruni VSK Chakravarthi, Pavithra Dedigama-Arachchige, Shannon Carskadon, Shanker Kalyana Sundaram, Jia Li, Kuan-Han Hank Wu, Darshan Shimoga Chandrashekar, James O Peabody, Hans Stricker, Clara Hwang, Dhananjay A Chitale, Sean R Williamson, Nilesh S Gupta, Nora M Navone, Craig Rogers, Mani Menon, Sooryanarayana Varambally, Nallasivam PalanisamyAbstractWe pr

  Neoplasia

  Thu Aug 22, 2019 04:39
• Reversine inhibits MMP-3, IL-6 and IL-8 expression through suppression of ROS and JNK/AP-1 activation in interleukin-1β-stimulated human gingival fibroblasts

  Publication date: Available online 21 August 2019Source: Archives of Oral BiologyAuthor(s): Hyun-Kyung Song, Eun-Mi Noh, Jeong-Mi Kim, Yong-Ouk You, Kang-Beom Kwon, Young-Rae LeeAbstractObjectivePeriodontitis is an inflammatory disease of the supporting tissue around teeth commonly caused by gram-negative bacterial infections. Interleukin (IL)-1β, a cytokine involved in host immune and inflammatory responses, is known to induce the activati

  Oral Biology

  Thu Aug 22, 2019 04:36
• Oncologic Accuracy of Image-guided Percutaneous Core-Needle Biopsy of Peripheral Nerve Sheath Tumors at a High-volume Sarcoma Center

  Objectives: Peripheral nerve sheath tumors (PNSTs) are clinically heterogenous, comprising benign (BPNST) and malignant (MPNST) variants. BPNSTs can be managed with nerve-sparing excision or observation. MPNSTs require radical resection and multidisciplinary oncologic management (1, 15). Image-guided core-needle biopsy (IGCNBx) is the well-established standard to obtain preoperative tissue diagnosis of soft tissue tumors. However, there has be

  American Journal of Clinical Oncology - Published Ahead-of-Print

  Mon Aug 19, 2019 17:00
• Extraskeletal Myxoid Chondrosarcomas: Combined Modality Therapy With Both Radiation and Surgery Improves Local Control

  Objective: We evaluated our experience treating patients with localized extraskeletal myxoid chondrosarcomas (EMCs) to evaluate outcomes and relapse rates in order to better inform treatment decisions for these rare soft tissue sarcomas. Materials and Methods: We reviewed the records of 41 consecutive patients with localized EMC treated at our institution from 1990 to 2016. Most patients (n=33, 80%) received combined modality therapy with

  American Journal of Clinical Oncology - Published Ahead-of-Print

  Mon Aug 19, 2019 17:00
• The Role of Partial Breast Radiation in the Previously Radiated Breast

  Objectives: The aim of this study was to analyze breast cancer patients who previously had mantle-field or breast radiation (RT) followed by retreatment with external beam partial breast irradiation (EB PBI). Materials and Methods: We retrospectively reviewed all women with newly diagnosed early-stage breast cancer treated with lumpectomy and partial breast irradiation between 2007 and 2017 who had undergone prior chest or breast RT. Re

  American Journal of Clinical Oncology - Published Ahead-of-Print

  Mon Aug 19, 2019 17:00
• Modern Outcomes Following Treatment of Hepatocellular Carcinoma in Hereditary Hemochromatosis: A Matched Cohort Study

  Objective: Hepatocellular carcinoma (HCC) is a complication of the common genetic condition hereditary hemochromatosis (HH). It is unknown whether HH as an etiology of liver disease impacts the outcome. We compared the results of liver transplantation (LT), surgical resection and locoregional therapies in a matched cohort study and investigated whether HH as an etiology has an impact on survival. Materials and Methods: Consecutive patient

  American Journal of Clinical Oncology - Published Ahead-of-Print

  Mon Aug 19, 2019 17:00
• Sublingual immunotherapy and omalizumab cured allergic chronic rhinosinusitis and asthma: coincidence or synergistic effect?

  Publication date: Available online 21 August 2019Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): George N. Konstantinou, Elisavet Kaitalidou, Nikos Skoulikaris

  ScienceDirect Publication: Annals of Allergy, Asthma & Immunology

  Thu Aug 22, 2019 04:17
• Efficacy and tolerability of intravenous immunoglobulin and subcutaneous immunoglobulin in neurologic diseases

  Publication date: Available online 21 August 2019Source: Clinical TherapeuticsAuthor(s): Yun Chen, Chunyu Wang, Fanxi Xu, Fengyu Ming, Hainan ZhangAbstractPurposeIV immunoglobulin (Ig) therapy has been widely used for the treatment of neurologic disorders, autoimmune diseases, immunodeficiency-related diseases, blood system diseases, and cancers. In this review, we summarize the efficacy and tolerability of IVIg and SCIg therapy in neurologic di

  Clinical Therapeutics

  Thu Aug 22, 2019 04:15
• Antidepressants upregulate c-Fos expression in the lateral entorhinal cortex and hippocampal dorsal subiculum: study in rats

  Publication date: Available online 21 August 2019Source: Brain Research BulletinAuthor(s): Ilya D. Ionov, Irina I. Pushinskaya, Niсholas P. Gorev, David D. FrenkelAbstractNeural circuits involved in the development of depression are currently poorlyunderstood. To provide insight into this issue, we evaluated the influence of seven clinically effective antidepressants on neuronal activity in thirty rat brain areas. Drugs belonging to all ma

  ScienceDirect Publication: Brain Research Bulletin

  Thu Aug 22, 2019 04:03
• Hippocampal PPARα is involved in the antidepressant-like effects of venlafaxine in mice

  Publication date: Available online 21 August 2019Source: Brain Research BulletinAuthor(s): Cheng Chen, Jian-Hong Shen, Hui Xu, Peng Chen, Fei Chen, Yi-Xiang Guan, Bo Jiang, Zhong-Hua WuAbstractAlthough thought as a serotonin and norepinephrine reuptake inhibitor (SNRI), the antidepressant mechanisms of venlafaxine remain unknown. Previous reports have shown the role of peroxisome proliferator activated receptor α (PPARα) in depressio

  ScienceDirect Publication: Brain Research Bulletin

  Thu Aug 22, 2019 04:03
• Switchable magnetic bulk photovoltaic effect in the two-dimensional magnet CrI₃

  Nature Communications, Published online: 22 August 2019; doi:10.1038/s41467-019-11832-3Two dimensional (2D) material with intriguing physical properties promises advanced electronic and spintronic technologies. Here the authors predict a magnetic photo-galvanic effect (MPGE) in bilayer 2D CrI3 due to the magnetism-induced asymmetry of the carrier velocity in the band-structure topology.

  Nature Communications - current - nature.com science feeds

  Wed Aug 21, 2019 17:00
• Quantifying the nonclassicality of pure dephasing

  Nature Communications, Published online: 22 August 2019; doi:10.1038/s41467-019-11502-4The presence of processes that cannot be simulated classically in open quantum system dynamics is acknowledged, but an exact quantifier for this non-classical character is still missing. Here, the authors provide a quantitative measure of non-classicality for purely dephasing evolutions.

  Nature Communications - current - nature.com science feeds

  Wed Aug 21, 2019 17:00