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Τετάρτη, 21 Αυγούστου 2019

Kaposi sarcoma of the upper eyelid: a rare occurrence.
Related ArticlesKaposi sarcoma of the upper eyelid: a rare occurrence. Clin Exp Ophthalmol. 2018 12;46(9):1097-1098 Authors: Curragh DS, Chang S, Selva D PMID: 29888854 [PubMed - indexed for MEDLINE]
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Management of thyroid cytological material, preanalytical procedures and bio-banking.
Related ArticlesManagement of thyroid cytological material, preanalytical procedures and bio-banking. Cytopathology. 2019 01;30(1):7-16 Authors: Bode-Lesniewska B, Cochand-Priollet B, Straccia P, Fadda G, Bongiovanni M Abstract Thyroid nodules are common and are increasingly detected due to recent advances in imaging techniques. However, clinically relevant thyroid cancer is rare and the mortality from aggressive thyroid cancer remains constant. Fine...
!@ Rare Cancers
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Abdominal lymphatic malformations.
Related ArticlesAbdominal lymphatic malformations. Radiologe. 2018 Nov;58(Suppl 1):29-33 Authors: Wohlgemuth WA, Brill R, Dendl LM, Stangl F, Stoevesandt D, Schreyer AG Abstract BACKGROUND: Abdominal lymphatic malformations (LM) are relatively rare findings in the differential diagnosis of focal abdominal lesions; however, they represent a challenge especially in younger patients. The aim of this review article is to provide up-to-date information about...
!@ Rare Cancers
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The added value of chemical shift MRI in the preoperative diagnosis of thymolipoma.
Related ArticlesThe added value of chemical shift MRI in the preoperative diagnosis of thymolipoma. Tumori. 2018 Dec;104(6):NP57-NP60 Authors: Calandriello L, Larici AR, Sica G, Ciliberto M, Manfredi R Abstract Thymolipoma is a rare tumor of the thymus. Classic radiologic findings of thymolipoma include fatty masses of the anterior mediastinum in conjunction with the thymus. Differential diagnosis with other more aggressive entities like liposarcoma...
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Localized morphea after breast implant for breast cancer: A case report.
Related ArticlesLocalized morphea after breast implant for breast cancer: A case report. Tumori. 2018 Dec;104(6):NP25-NP28 Authors: Moretti A, Bianchi F, Abbate IV, Gherardi G, Bonavita M, Passoni E, Nazzaro G, Bramati A, Dazzani MC, Piva S, Paternò E, Frungillo N, Farina G, La Verde N Abstract PURPOSE: Early breast cancer follow-up guidelines for patients who underwent surgery suggest a regular and accurate clinical examination of the breast area,...
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Hypereosinophilic syndrome preceding a diagnosis of B-cell lymphoma.
Related ArticlesHypereosinophilic syndrome preceding a diagnosis of B-cell lymphoma. Tumori. 2018 Dec;104(6):NP22-NP24 Authors: Samarghandi A, Ahuja S, Jindal V, Gupta S, Fulger I Abstract INTRODUCTION: Hypereosinophilic syndrome (HES) is a rare condition characterized by eosinophilia and organ destruction secondary to eosinophilic infiltration. The coexistence of primary B-cell lymphoma and hypereosinophilic syndrome is extremely rare. We present a...
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Retrospective Analysis of Outcome of Patients with Metastatic Leiomyosarcoma in a Tertiary Referral Center.
Related ArticlesRetrospective Analysis of Outcome of Patients with Metastatic Leiomyosarcoma in a Tertiary Referral Center. Oncol Res Treat. 2018;41(4):206-213 Authors: van Cann T, Cornillie J, Wozniak A, Debiec-Rychter M, Sciot R, Hompes D, Vergote I, Schöffski P Abstract BACKGROUND: Leiomyosarcoma is a common subtype of soft tissue sarcoma originating from smooth muscle. We evaluated the clinical course and treatment outcome of patients with metastatic...
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Thoracolithiasis: A Rare Cause of Multiple Nodules.
Related ArticlesThoracolithiasis: A Rare Cause of Multiple Nodules. Am J Respir Crit Care Med. 2018 05 01;197(9):1212-1213 Authors: Hochhegger B, Camargo SM, Nascimento D, Zanetti G, Marchiori E PMID: 29490153 [PubMed - indexed for MEDLINE]
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Sarcomas of the sinonasal tract.
Related ArticlesSarcomas of the sinonasal tract. Head Neck. 2018 06;40(6):1279-1286 Authors: Kauke M, Safi AF, Grandoch A, Nickenig HJ, Zöller J, Kreppel M Abstract BACKGROUND: Sinonasal sarcomas are rare and heterogeneous in nature. Continuously collecting data influencing the prognosis is fundamental for optimizing therapeutic assessment of this highly destructive neoplasm. METHODS: We conducted a single-institution retrospective cohort study...
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Intraoperative cardiac arrest etiologies in head and neck surgery: A comprehensive review.
Related ArticlesIntraoperative cardiac arrest etiologies in head and neck surgery: A comprehensive review. Head Neck. 2018 06;40(6):1299-1304 Authors: Tarabanis C, Abt NB, Osborn HA Abstract BACKGROUND: The etiologies of intraoperative cardiac arrest within otolaryngology are not well understood as they are rare events. METHODS: A comprehensive review of the etiologies and corresponding pathophysiologic neural mechanisms of intraoperative cardiac...
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Isolated Scapular Metastasis in a Patient with Malignant Struma Ovarii: A Case Report.
Related ArticlesIsolated Scapular Metastasis in a Patient with Malignant Struma Ovarii: A Case Report. JBJS Case Connect. 2017 Oct-Dec;7(4):e82 Authors: Comunello J, Eloi Pinto FF, Nakagawa SA, Tu Chung W, D'Almeida Costa F, Brilhante AD Abstract CASE: We report the case of a 38-year-old woman who presented with a lytic bone lesion in the left scapula. A biopsy showed a tumor with the histologic appearance of thyroid tissue. She also was found to have...
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Coordinated repression of BIM and PUMA by Epstein-Barr virus latent genes maintains the survival of Burkitt lymphoma cells.
Related ArticlesCoordinated repression of BIM and PUMA by Epstein-Barr virus latent genes maintains the survival of Burkitt lymphoma cells. Cell Death Differ. 2018 02;25(2):241-254 Authors: Fitzsimmons L, Boyce AJ, Wei W, Chang C, Croom-Carter D, Tierney RJ, Herold MJ, Bell AI, Strasser A, Kelly GL, Rowe M Abstract While the association of Epstein-Barr virus (EBV) with Burkitt lymphoma (BL) has long been recognised, the precise role of the virus in...
!@ Rare Cancers
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Genomic profiling reveals mutational landscape in parathyroid carcinomas.
Related ArticlesGenomic profiling reveals mutational landscape in parathyroid carcinomas. JCI Insight. 2017 03 23;2(6):e92061 Authors: Pandya C, Uzilov AV, Bellizzi J, Lau CY, Moe AS, Strahl M, Hamou W, Newman LC, Fink MY, Antipin Y, Yu W, Stevenson M, Cavaco BM, Teh BT, Thakker RV, Morreau H, Schadt EE, Sebra R, Li SD, Arnold A, Chen R Abstract Parathyroid carcinoma (PC) is an extremely rare malignancy lacking effective therapeutic intervention. We...
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Cardiac leiomyosarcoma: a rare cause of acute and progressive dyspnoea.
Related ArticlesCardiac leiomyosarcoma: a rare cause of acute and progressive dyspnoea. Eur Heart J. 2017 05 21;38(20):1614-1615 Authors: Bigalke B, Lohneis P, Blohmer JU, Jacobs S, Landmesser U PMID: 28201560 [PubMed - indexed for MEDLINE]
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A new pattern of lipomatosis of nerve: case report.
Related ArticlesA new pattern of lipomatosis of nerve: case report. J Neurosurg. 2017 Mar;126(3):933-937 Authors: Prasad NK, Mahan MA, Howe BM, Amrami KK, Spinner RJ Abstract Lipomatosis of nerve (LN) is a rare disorder of peripheral nerves that produces proliferation of interfascicular adipose tissue. It may be associated with soft-tissue and bony overgrowth within the affected nerve territory. LN has been almost exclusively reported in appendicular...
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Stereotactic radiosurgery for intracranial hemangiopericytomas: a multicenter study.
Related ArticlesStereotactic radiosurgery for intracranial hemangiopericytomas: a multicenter study. J Neurosurg. 2017 Mar;126(3):744-754 Authors: Cohen-Inbar O, Lee CC, Mousavi SH, Kano H, Mathieu D, Meola A, Nakaji P, Honea N, Johnson M, Abbassy M, Mohammadi AM, Silva D, Yang HC, Grills I, Kondziolka D, Barnett GH, Lunsford LD, Sheehan J Abstract OBJECTIVE Hemangiopericytomas (HPCs) are rare tumors widely recognized for their aggressive clinical behavior,...
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Comments about the article "A Crouzon syndrome from the classic period of Maya civilization?" The art historian's point of view.
Related ArticlesComments about the article "A Crouzon syndrome from the classic period of Maya civilization?" The art historian's point of view. Surg Radiol Anat. 2019 Aug 16;: Authors: Trost O, Micoud S, Duparc F PMID: 31420723 [PubMed - as supplied by publisher]
radiol anat
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Neglected orbitozygomaticomaxillary fractures with complications: A case report.
Related ArticlesNeglected orbitozygomaticomaxillary fractures with complications: A case report. Int J Surg Case Rep. 2019 Jul 26;62:35-39 Authors: Isya Wahdini S, Dachlan I, Seswandhana R, Hutagalung MR, Putri IL, Afandy D Abstract INTRODUCTION: Zygomatic complex fracture is one of the most frequently occuring injuries to facial structures and often involves damage to the surrounding structures, including the orbital floor and/or medial orbital wall....
pubmed: "int j surg case rep...
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Complex upper limb reconstruction using dorsoepigastric flap. Case report of a convenient resource.
Related ArticlesComplex upper limb reconstruction using dorsoepigastric flap. Case report of a convenient resource. Int J Surg Case Rep. 2019 Aug 09;62:31-34 Authors: Jimenez Muñoz-Ledo G, Melgosa-Juárez M, Palacios-Júárez J, Morales-Maza J, Rodríguez-Quintero JH Abstract INTRODUCTION: Dorsoepigastric flap (DF), first described by. Haddad and Jimenez, is a variant of the classic lattisimus dorsi musculocutaneous flap that only utilizes a minimum quantity...
pubmed: "int j surg case rep...
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Laparoscopic excision of a retroperitoneal mucinous cystic neoplasm: A case report.
Related ArticlesLaparoscopic excision of a retroperitoneal mucinous cystic neoplasm: A case report. Int J Surg Case Rep. 2019 Jul 19;62:27-30 Authors: Lung J, Gracey A, Rosales A, Bashover E, Sbar A, Nazim MH, Rico F Abstract INTRODUCTION: A 22-year-old female presented with a large abdominal mass that was revealed to be a primary retroperitoneal mucinous cystadenoma. PRESENTATION OF CASE: A 22-year-old female presented with a two day history...
pubmed: "int j surg case rep...
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Histological evaluation of the healing process of autografted mandibular bone defects in rats under treatment with zoledronate
Publication date: Available online 19 August 2019Source: Journal of Cranio-Maxillofacial SurgeryAuthor(s): Mohammad Zandi, Arash Dehghan, Ideh Talimkhani, Leila Rezaeian, Naser Mohammad Gholi MezerjiAbstractObjectiveThis study aims to evaluate the healing process of autografted mandibular bone defects in rats treated with zoledronate (ZOL).Subjectsand methods: A total of 180 Wistar rats were divided into four groups: group L received intravenous infusion of two doses of 0.06 mg/kg ZOL, nine weeks...
Cranio-Maxillofacial Surgery
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An oral 2-hydroxypropyl-β-cyclodextrin-loaded spirooxindole-pyrrolizidine derivative restores p53 activity via targeting MDM2 and JNK1/2 in hepatocellular carcinoma.
Related ArticlesAn oral 2-hydroxypropyl-β-cyclodextrin-loaded spirooxindole-pyrrolizidine derivative restores p53 activity via targeting MDM2 and JNK1/2 in hepatocellular carcinoma. Pharmacol Res. 2019 Aug 16;:104400 Authors: Gao X, Wei M, Shan W, Liu Q, Gao J, Liu Y, Zhu S, Yao H Abstract Validation of a small molecular compound targeting the oncogenic pathways is the primary approach for the development of the anti-cancer drugs. In the present study,...
pubmed: cell cycle arrest
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Astragalin induced selective kidney cancer cell death and these effects are mediated via mitochondrial mediated cell apoptosis, cell cycle arrest, and modulation of key tumor-suppressive miRNAs.
Related ArticlesAstragalin induced selective kidney cancer cell death and these effects are mediated via mitochondrial mediated cell apoptosis, cell cycle arrest, and modulation of key tumor-suppressive miRNAs. J BUON. 2019 May-Jun;24(3):1245-1251 Authors: Zhu L, Zhu L, Chen J, Cui T, Liao W Abstract PURPOSE: Kidney cancer is responsible for a significant number of deaths worldwide. This cancer is often diagnosed at advanced stages and there are frequent...
pubmed: cell cycle arrest
22h
In vitro and in vivo growth inhibition of human leukemia cells by Nodakenetin are mediated via mitochondrial apoptosis, cell cycle arrest and inhibition of cell migration and invasion.
Related ArticlesIn vitro and in vivo growth inhibition of human leukemia cells by Nodakenetin are mediated via mitochondrial apoptosis, cell cycle arrest and inhibition of cell migration and invasion. J BUON. 2019 May-Jun;24(3):1219-1224 Authors: Lei P, Liao C, Chen J, Zhou M Abstract PURPOSE: To study the anticancer potential of a plant-derived coumarin, Nodakenetin, against acute lymphocytic leukemia HL-60 cells. METHODS: The proliferation...
pubmed: cell cycle arrest
22h
Antitumor activity of Cedrelone in temozolomide-resistant human glioma cells is accompanied by mitochondrial mediated apoptosis, inhibition of angiogenesis, cell cycle disruption and modulation of ERK/MAPK signalling pathway.
Related ArticlesAntitumor activity of Cedrelone in temozolomide-resistant human glioma cells is accompanied by mitochondrial mediated apoptosis, inhibition of angiogenesis, cell cycle disruption and modulation of ERK/MAPK signalling pathway. J BUON. 2019 May-Jun;24(3):1204-1209 Authors: Cao Y, Zhang L, Wang Y Abstract PURPOSE: Glioma is one of the most aggressive types of human cancers and responsible for considerable mortality across the globe. Moreover,...
pubmed: cell cycle arrest
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A flavone, Wogonin from Scutellaria baicalensis inhibits the proliferation of human colorectal cancer cells by inducing of autophagy, apoptosis and G2/M cell cycle arrest via modulating the PI3K/AKT and STAT3 signalling pathways.
Related ArticlesA flavone, Wogonin from Scutellaria baicalensis inhibits the proliferation of human colorectal cancer cells by inducing of autophagy, apoptosis and G2/M cell cycle arrest via modulating the PI3K/AKT and STAT3 signalling pathways. J BUON. 2019 May-Jun;24(3):1143-1149 Authors: Tan H, Li X, Yang WH, Kang Y Abstract PURPOSE: The purpose of this study was to examine the anticancer effects of a flavone from Scutellaria baicalensis wogonin against...
pubmed: cell cycle arrest
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In vitro and in vivo human gastric cancer inhibition by Trifolirhizin is facilitated via autophagy, mitochondrial mediated programmed cell death, G2/M phase cell cycle arrest and inhibition of m-TOR/PI3K/AKT signalling pathway.
Related ArticlesIn vitro and in vivo human gastric cancer inhibition by Trifolirhizin is facilitated via autophagy, mitochondrial mediated programmed cell death, G2/M phase cell cycle arrest and inhibition of m-TOR/PI3K/AKT signalling pathway. J BUON. 2019 May-Jun;24(3):1100-1105 Authors: Zhang K, Liu W, Qu Z, Liu Q, Chen J, Tao R, Deng Y, Zhang Y Abstract PURPOSE: To investigate the anticancer effects of Trifolirhizin in SNU-5 human gastric cancer cells...
pubmed: cell cycle arrest
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MicroRNA-155regulates the proliferation and metastasis of human breast cancers by targeting MAPK7.
Related ArticlesMicroRNA-155regulates the proliferation and metastasis of human breast cancers by targeting MAPK7. J BUON. 2019 May-Jun;24(3):1075-1080 Authors: Liu JH, Yang Y, Song Q, Li JB Abstract PURPOSE: Breast cancer causes significant mortality in women world over. The lack of efficient and reliable biomarkers and therapeutic targets impedes the treatment of breast cancer. Herein, the role and therapeutic potential of miR-155 was investigated...
pubmed: cell cycle arrest
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MicroRNA-204 inhibits the proliferation and metastasis of breast cancer cells by targeting PI3K/AKT pathway.
Related ArticlesMicroRNA-204 inhibits the proliferation and metastasis of breast cancer cells by targeting PI3K/AKT pathway. J BUON. 2019 May-Jun;24(3):1054-1059 Authors: Fan X, Fang X, Liu G, Xiong Q, Li Z, Zhou W Abstract PURPOSE: Breast cancer is one of the deadliest malignancies in women. Lack of biomarkers and the unavailability of reliable therapeutic targets are main hurdles in the treatment of breast cancer. The present study was therefore designed...
pubmed: cell cycle arrest
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Scopoletin exerts anticancer effects on human cervical cancer cell lines by triggering apoptosis, cell cycle arrest, inhibition of cell invasion and PI3K/AKT signalling pathway.
Related ArticlesScopoletin exerts anticancer effects on human cervical cancer cell lines by triggering apoptosis, cell cycle arrest, inhibition of cell invasion and PI3K/AKT signalling pathway. J BUON. 2019 May-Jun;24(3):997-1002 Authors: Tian Q, Wang L, Sun X, Zeng F, Pan Q, Xue M Abstract PURPOSE: Cervical cancer causes considerable mortality in women world over and the current treatment options create severe adverse effects. Hence, there is an urgent...
pubmed: cell cycle arrest
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Kaempferol exerts anti-proliferative effects on human ovarian cancer cells by inducing apoptosis, G0/G1 cell cycle arrest and modulation of MEK/ERK and STAT3 pathways.
Related ArticlesKaempferol exerts anti-proliferative effects on human ovarian cancer cells by inducing apoptosis, G0/G1 cell cycle arrest and modulation of MEK/ERK and STAT3 pathways. J BUON. 2019 May-Jun;24(3):975-981 Authors: Yang S, Si L, Jia Y, Jian W, Yu Q, Wang M, Lin R Abstract PURPOSE: Ovarian cancer causes significant mortality in women and is one of the most prevalent types of gynaecological cancer world over. Ovarian cancer is often diagnosed...
pubmed: cell cycle arrest
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In vitro and in vivo cytotoxic effects of chrysoeriol in human lung carcinoma are facilitated through activation of autophagy, sub-G1/G0 cell cycle arrest, cell migration and invasion inhibition and modulation of MAPK/ERK signalling pathway.
Related ArticlesIn vitro and in vivo cytotoxic effects of chrysoeriol in human lung carcinoma are facilitated through activation of autophagy, sub-G1/G0 cell cycle arrest, cell migration and invasion inhibition and modulation of MAPK/ERK signalling pathway. J BUON. 2019 May-Jun;24(3):936-942 Authors: Wei W, He J, Ruan H, Wang Y Abstract PURPOSE: Lung cancer is a malignancy that imposes huge health, psychological and financial burden on patients and their...
pubmed: cell cycle arrest
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E2F1 proteolysis via SCF-cyclin F underlies synthetic lethality between cyclin F loss and Chk1 inhibition.
Related ArticlesE2F1 proteolysis via SCF-cyclin F underlies synthetic lethality between cyclin F loss and Chk1 inhibition. EMBO J. 2019 Aug 19;:e101443 Authors: Burdova K, Yang H, Faedda R, Hume S, Chauhan J, Ebner D, Kessler BM, Vendrell I, Drewry DH, Wells CI, Hatch SB, Dianov GL, Buffa FM, D'Angiolella V Abstract Cyclins are central engines of cell cycle progression in conjunction with cyclin-dependent kinases (CDKs). Among the different cyclins controlling...
pubmed: cell cycle arrest
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Chaetocin induces caspase-dependent apoptosis in ovarian cancer cells via the generation of reactive oxygen species.
Related ArticlesChaetocin induces caspase-dependent apoptosis in ovarian cancer cells via the generation of reactive oxygen species. Oncol Lett. 2019 Aug;18(2):1915-1921 Authors: Li Z, Huang L, Wei L, Hou Z, Ye W, Huang S Abstract Ovarian cancer (OC) is one of the most common types of cancer among women worldwide. The majority of patients with OC respond to current chemotherapy approaches initially; however, patients are likely to experience cancer recurrence...
pubmed: cell cycle arrest
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CDS-1548 induces apoptosis in HeLa cells by activating caspase 3.
Related ArticlesCDS-1548 induces apoptosis in HeLa cells by activating caspase 3. Oncol Lett. 2019 Aug;18(2):1881-1887 Authors: Zhang Y, Ge Y, Shi W, Hu C, Bai X, Rong J, Yu M Abstract Cervical cancer continues to be a threat to female health globally. In the present study, the potential anticancer activity of 2-[2-hydroxyl-1-(4-methoxy phenyl) ethyl]-3-(4-benzyloxy phenyl) isoindolin-1-one (CDS-1548), was evaluated in HeLa cells. CDS-1548 is an organic...
pubmed: cell cycle arrest
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Pterostilbene inhibits lung squamous cell carcinoma growth in vitro and in vivo by inducing S phase arrest and apoptosis.
Related ArticlesPterostilbene inhibits lung squamous cell carcinoma growth in vitro and in vivo by inducing S phase arrest and apoptosis. Oncol Lett. 2019 Aug;18(2):1631-1640 Authors: Tan KT, Chen PW, Li S, Ke TM, Lin SH, Yang CC Abstract Natural dietary components have become the subject of an increasing amount of interest due to the side effects of anticancer treatment. Pterostilbene, an analog of resveratrol, is primarily found in grapes, and has...
pubmed: cell cycle arrest
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Novel tumor-suppressor FOXN3 is downregulated in adult acute myeloid leukemia.
Related ArticlesNovel tumor-suppressor FOXN3 is downregulated in adult acute myeloid leukemia. Oncol Lett. 2019 Aug;18(2):1521-1529 Authors: He H, Zhang J, Qu Y, Wang Y, Zhang Y, Yan X, Li Y, Zhang R Abstract Forkhead box protein N3 (FOXN3) is a transcriptional repressor involved in cell cycle regulation and tumorigenesis. Abnormalities in gene structure and epigenetics of FOXN3 are closely associated with the occurrence of hematological malignancies;...
pubmed: cell cycle arrest
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Antiproliferative and antimigratory activities of bisphosphonates in human breast cancer cell line MCF-7.
Related ArticlesAntiproliferative and antimigratory activities of bisphosphonates in human breast cancer cell line MCF-7. Oncol Lett. 2019 Aug;18(2):1246-1258 Authors: Buranrat B, Bootha S Abstract Bisphosphonates (BPs) are antiresorptive drugs that act as effective inhibitors of cancer cell proliferation. However, not all bisphosphonates are equally effective against breast cancer cells in vitro. The present study investigated the extent to which three...
pubmed: cell cycle arrest
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Knockdown of long non-coding RNA PVT1 inhibits the proliferation of Raji cells through cell cycle regulation.
Related ArticlesKnockdown of long non-coding RNA PVT1 inhibits the proliferation of Raji cells through cell cycle regulation. Oncol Lett. 2019 Aug;18(2):1225-1234 Authors: Zheng C, Xiao Y, Li Y, He D Abstract Long non-coding RNA plasmacytoma variant translocation 1 (PVT1) has been reported to be associated with oncogenesis. However, the functional role of PVT1 in Burkitt lymphoma has not yet been addressed. The purpose of the present study was to investigate...
pubmed: cell cycle arrest
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OPCML: A Promising Biomarker and Therapeutic Avenue.
Related ArticlesOPCML: A Promising Biomarker and Therapeutic Avenue. Trends Cancer. 2019 Aug;5(8):463-466 Authors: Simovic I, Castaño-Rodríguez N, Kaakoush NO Abstract Opioid-binding protein/cell adhesion molecule (OPCML) is expressed in many tissues and localizes to the plasma membrane. It is a putative tumor suppressor that acts on receptor tyrosine kinases (RTKs), influencing cell cycle arrest, apoptosis, and migration. Its expression is silenced...
pubmed: cell cycle arrest
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Mitochondrial metabolic reprograming via BRAF inhibition ameliorates senescence.
Related ArticlesMitochondrial metabolic reprograming via BRAF inhibition ameliorates senescence. Exp Gerontol. 2019 Aug 14;:110691 Authors: Kim JW, Kuk MU, Choy HE, Park SC, Park JT Abstract Senescence is defined as irreversible cell cycle arrest and constitutes a major driving force in diseases related to aging or premature aging. Recent studies indicate that activation of the serine/threonine protein kinase B-raf (BRAF) plays important roles in oncogene-induced...
pubmed: cell cycle arrest
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Nano-Co-Delivery of Berberine and Anticancer Drug Using PLGA Nanoparticles: Exploration of Better Anticancer Activity and In Vivo Kinetics.
Related ArticlesNano-Co-Delivery of Berberine and Anticancer Drug Using PLGA Nanoparticles: Exploration of Better Anticancer Activity and In Vivo Kinetics. Pharm Res. 2019 Aug 16;36(10):149 Authors: Khan I, Joshi G, Nakhate KT, Ajazuddin, Kumar R, Gupta U Abstract PURPOSE: Combinatorial approach can be beneficial for cancer treatment with better patient recovery. Co-delivery of natural and synthetic anticancer drug not only valuable to achieve better...
pubmed: cell cycle arrest
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Acetyl-macrocalin B suppresses tumor growth in esophageal squamous cell carcinoma and exhibits synergistic anti-cancer effects with the Chk1/2 inhibitor AZD7762.
Related ArticlesAcetyl-macrocalin B suppresses tumor growth in esophageal squamous cell carcinoma and exhibits synergistic anti-cancer effects with the Chk1/2 inhibitor AZD7762. Toxicol Appl Pharmacol. 2019 02 15;365:71-83 Authors: Wang JN, Che Y, Yuan ZY, Lu ZL, Li Y, Zhang ZR, Li N, Li RD, Wan J, Sun HD, Sun N, Puno PT, He J Abstract Natural products derived from herbal medicines have become a major focus of anti-cancer drug discovery studies. Acetyl-macrocalin...
pubmed: cell cycle arrest
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DNA binding, cleavage and cytotoxicity studies of three mononuclear Cu(II) chloro-complexes containing N-S donor Schiff base ligands.
Related ArticlesDNA binding, cleavage and cytotoxicity studies of three mononuclear Cu(II) chloro-complexes containing N-S donor Schiff base ligands. J Biol Inorg Chem. 2018 12;23(8):1331-1349 Authors: Parsekar SU, Fernandes J, Banerjee A, Chouhan OP, Biswas S, Singh M, Mishra DP, Kumar M Abstract We report the biological activity of three Cu(II) complexes [Cu(pabt)Cl] (1), [Cu(pma)Cl] (2), and [Cu(pdta)Cl]Cl (3) (pabt = N-(2-mercaptophenyl)-2'-pyridylmethylenimine,...
pubmed: cell cycle arrest
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Improved anticancer effects of epigallocatechin gallate using RGD-containing nanostructured lipid carriers.
Related ArticlesImproved anticancer effects of epigallocatechin gallate using RGD-containing nanostructured lipid carriers. Artif Cells Nanomed Biotechnol. 2018;46(sup1):283-292 Authors: Hajipour H, Hamishehkar H, Nazari Soltan Ahmad S, Barghi S, Maroufi NF, Taheri RA Abstract The global burden of cancer have encouraged oncologists to develop novel strategies for treatment. Present study was proposed to develop Arginyl-glycyl-aspartic acid (RGD)-containing...
pubmed: cell cycle arrest
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Age, thyroglobulin levels and ATA risk stratification predict 10-year survival rate of differentiated thyroid cancer patients.
Related ArticlesAge, thyroglobulin levels and ATA risk stratification predict 10-year survival rate of differentiated thyroid cancer patients. PLoS One. 2019;14(8):e0221298 Authors: Kelly A, Barres B, Kwiatkowski F, Batisse-Lignier M, Aubert B, Valla C, Somda F, Cachin F, Tauveron I, Maqdasy S Abstract INTRODUCTION: Differentiated thyroid cancer (DTC) is the most common of endocrine cancers. Many studies have focused on recurrence-free survival of DTC...
radioactive iodine
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Predictive value of LN metastasis detected by 18F-FDG PET/CT in patients with papillary thyroid cancer receiving iodine-131 radiotherapy.
Related ArticlesPredictive value of LN metastasis detected by 18F-FDG PET/CT in patients with papillary thyroid cancer receiving iodine-131 radiotherapy. Oncol Lett. 2019 Aug;18(2):1641-1648 Authors: Li C, Zhang J, Wang H Abstract The aim of the present study was to predict the prognostic value of 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) in the metastatic lymph nodes (mLNs) of patients with papillary thyroid...
radioactive iodine
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Squamous cell carcinoma of the lung and pulmonary metastasis of papillary thyroid carcinoma: a case report.
Related ArticlesSquamous cell carcinoma of the lung and pulmonary metastasis of papillary thyroid carcinoma: a case report. J Med Case Rep. 2019 Aug 19;13(1):259 Authors: Aminorroaya A, Khoshniatnikoo M, Farrokhpour H, Vafaeimanesh J, Bagherzadeh M Abstract BACKGROUND: The coexistence of malignancies in a patient may be explained by the tumor-to-tumor metastasis phenomenon or multiple primary malignant tumors, both of which are not common findings. Here,...
radioactive iodine
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Iodate and nitrate transformation by Agrobacterium/Rhizobium related strain DVZ35 isolated from contaminated Hanford groundwater.
Related ArticlesIodate and nitrate transformation by Agrobacterium/Rhizobium related strain DVZ35 isolated from contaminated Hanford groundwater. J Hazard Mater. 2018 05 15;350:19-26 Authors: Lee BD, Ellis JT, Dodwell A, Eisenhauer EER, Saunders DL, Lee MH Abstract Nitrate and radioiodine (129I) contamination is widespread in groundwater underneath the Central Plateau of the Hanford Site. 129I, a byproduct of nuclear fission, is of concern due to a...
radioactive iodine
22h
Data-driven spatial filtering for improved measurement of cortical tracking of multiple representations of speech.
Related ArticlesData-driven spatial filtering for improved measurement of cortical tracking of multiple representations of speech. J Neural Eng. 2019 Aug 19;: Authors: Lesenfants D, Vanthornhout J, Verschueren E, Francart T Abstract Objective - Measurement of the cortical tracking of continuous speech from electroencephalography (EEG) recordings using a forward model is an important tool in auditory neuroscience. Usually the stimulus is represented by...
J Neural Eng
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Evaluation of methodologies for computing the deep brain stimulation volume of tissue activated.
Related ArticlesEvaluation of methodologies for computing the deep brain stimulation volume of tissue activated. J Neural Eng. 2019 Aug 19;: Authors: Duffley G, Anderson DN, Vorwerk J, Dorval AC, Butson CR Abstract OBJECTIVE: Computational models are a popular tool for predicting the effects of deep brain stimulation (DBS) on neural tissue. One commonly used model, the volume of tissue activated (VTA), is computed using multiple methodologies. We quantified...
J Neural Eng
23h
Obstructive Sleep Apnea and Airway Dimensions in COPD.
Related ArticlesObstructive Sleep Apnea and Airway Dimensions in COPD. Ann Am Thorac Soc. 2019 Aug 19;: Authors: Koch AL, Brown RH, Woo H, Brooker AC, Paulin LM, Schneider H, Schwartz AR, Diette GB, Wise RA, Hansel NN, Putcha N PMID: 31425663 [PubMed - as supplied by publisher]
pubmed: sleep apnea
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Obstructive Sleep Apnea and Perioperative Outcomes: We Should Not Confuse the Probability With the Established Diagnosis.
Related ArticlesObstructive Sleep Apnea and Perioperative Outcomes: We Should Not Confuse the Probability With the Established Diagnosis. Anesth Analg. 2019 Sep;129(3):e106-e107 Authors: Deflandre EP, Brichant JH PMID: 31425244 [PubMed - in process]
pubmed: sleep apnea
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Postoperative Respiratory Depression May Be Related to Undiagnosed Sleep-Disordered Breathing or Obstructive Sleep Apnea.
Related ArticlesPostoperative Respiratory Depression May Be Related to Undiagnosed Sleep-Disordered Breathing or Obstructive Sleep Apnea. Anesth Analg. 2019 Sep;129(3):e104-e105 Authors: Elleby LM, Sprung J, Weingarten TN PMID: 31425241 [PubMed - in process]
pubmed: sleep apnea
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Strong coincidence between slow wave sleep and low AHI is explainable by the high instability of slow wave sleep to obstructive apnea exposure.
Related ArticlesStrong coincidence between slow wave sleep and low AHI is explainable by the high instability of slow wave sleep to obstructive apnea exposure. Physiol Res. 2019 Aug 19; Authors: Peregrim I, Grešová S, Štimmelová J, Bačová I, Fulton BL, Tokárová D, Gáborová M, Brandeburová A, Doničová V, Rusnáková S, Tomori Z, Donič V Abstract It is well known that in patients with obstructive sleep apnea syndrome (OSAS) the apnea-hypopnea index (AHI)...
pubmed: sleep apnea
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The role of polysomnography in tracheostomy decannulation of children with bronchopulmonary dysplasia.
Related ArticlesThe role of polysomnography in tracheostomy decannulation of children with bronchopulmonary dysplasia. Pediatr Pulmonol. 2019 Aug 19;: Authors: Quinlan C, Piccione J, Kim JY, Beck SE, Brooks L, Chandy-Patel R, Escobar E, Afolabi-Brown O Abstract BACKGROUND: Patients with bronchopulmonary dysplasia (BPD) may require tracheostomy for long-term mechanical ventilation. Polysomnography (PSG) may predict successful decannulation in children,...
pubmed: sleep apnea
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Effects of sympathetic modulation in metabolic disease.
Related ArticlesEffects of sympathetic modulation in metabolic disease. Ann N Y Acad Sci. 2019 Aug 19;: Authors: Carnagarin R, Lambert GW, Kiuchi MG, Nolde JM, Matthews VB, Eikelis N, Lambert EA, Schlaich MP Abstract Sympathetic overdrive contributes to the derangement of glucose metabolism evident in clinical conditions, such as obesity, metabolic syndrome, type 2 diabetes, obstructive sleep apnea, and others. Targeting the sympathetic nervous system...
pubmed: sleep apnea
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The Prevalence of Sleep Apnea in Iran: a Systematic Review and Meta-Analysis.
Related ArticlesThe Prevalence of Sleep Apnea in Iran: a Systematic Review and Meta-Analysis. Tanaffos. 2019 Jan;18(1):1-10 Authors: Sarokhani M, Goli M, Salarvand S, Ghanei Gheshlagh R Abstract Background: Sleep apnea is a common sleep disorder which is associated with cardiovascular diseases, diabetes and stroke. Different studies conducted in Iran have reported different prevalence for sleep apnea. The aim of the present study was to determine the...
pubmed: sleep apnea
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Janus looks both ways: How do the upper and lower airways interact?
Related ArticlesJanus looks both ways: How do the upper and lower airways interact? Paediatr Respir Rev. 2019 Jun 26;: Authors: de Benedictis FM, Bush A Abstract Our understanding of the relationship between the upper and lower airways has greatly increased as a consequence of epidemiologic and pharmacologic studies. A consistent body of scientific evidence supports the concept that rhinitis, rhinosinusitis and asthma may be the expression of a common...
pubmed: sleep apnea
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Deep learning approaches for automatic detection of sleep apnea events from an electrocardiogram.
Related ArticlesDeep learning approaches for automatic detection of sleep apnea events from an electrocardiogram. Comput Methods Programs Biomed. 2019 Jul 30;180:105001 Authors: Erdenebayar U, Kim YJ, Park JU, Joo EY, Lee KJ Abstract BACKGROUND AND OBJECTIVE: This study demonstrates deep learning approaches with an aim to find the optimal method to automatically detect sleep apnea (SA) events from an electrocardiogram (ECG) signal. METHODS:...
pubmed: sleep apnea
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Echocardiographic screening in children with very severe obstructive sleep apnea.
Related ArticlesEchocardiographic screening in children with very severe obstructive sleep apnea. Int J Pediatr Otorhinolaryngol. 2019 Aug 08;126:109626 Authors: Teplitzky TB, Pereira KD, Isaiah A Abstract OBJECTIVE: (i) To determine the prevalence of echocardiographic abnormalities in children with very severe OSA defined by an apnea hypopnea index (AHI) ≥ 30 events/hour. (ii) To test the hypothesis that polysomnographic parameters predict echocardiographic...
pubmed: sleep apnea
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Continuous Positive Airway Pressure use for Obstructive Sleep Apnea in Acute, Traumatic Tetraplegia.
Related ArticlesContinuous Positive Airway Pressure use for Obstructive Sleep Apnea in Acute, Traumatic Tetraplegia. Arch Phys Med Rehabil. 2019 Aug 14;: Authors: Graco M, Schembri R, Ross J, Green SE, Booker L, Cistulli PA, Ayas NT, Berlowitz DJ, COSAQ investigators, Lee B, Graham A, Cross SV, McClelland M, Thumbikat P, Bennett C, Townson A, Geraghty TJ, Pieri-Davies S, Singhal R, Marshall K, Short D, Nunn A, Brown D Abstract OBJECTIVE: To describe...
pubmed: sleep apnea
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Hypoxic ventilatory response after rocuronium-induced partial neuromuscular blockade in men with obstructive sleep apnoea.
Related ArticlesHypoxic ventilatory response after rocuronium-induced partial neuromuscular blockade in men with obstructive sleep apnoea. Anaesthesia. 2019 Aug 17;: Authors: Christensson E, Ebberyd A, Hårdemark Cedborg A, Lodenius Å, Österlund Modalen Å, Franklin KA, Eriksson LI, Jonsson Fagerlund M Abstract Obstructive sleep apnoea and residual neuromuscular blockade are, independently, known to be risk factors for respiratory complications after major...
pubmed: sleep apnea
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Association between the ADAMTS proteinases and obstructive sleep apnea.
Related ArticlesAssociation between the ADAMTS proteinases and obstructive sleep apnea. Sleep Breath. 2019 Aug 16;: Authors: Sarioglu N, Erel F, Hismioğullari AA, Cevik C Abstract BACKGROUND: A disintegrin and metalloproteinase with thrombospondin type-1 motifs (ADAMTS) proteinases have important roles in degradation/repairing of extracellular matrix (ECM). They are thought to play a key role in pathogenesis of many diseases. We aimed to investigate...
pubmed: sleep apnea
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Muscarinic inhibition of hypoglossal motoneurons: possible implications for upper airway muscle hypotonia during REM sleep.
Related ArticlesMuscarinic inhibition of hypoglossal motoneurons: possible implications for upper airway muscle hypotonia during REM sleep. J Neurosci. 2019 Aug 16;: Authors: Zhu L, Chamberlin NL, Arrigoni E Abstract Proper function of pharyngeal dilator muscles, including the genioglossus muscle of the tongue, is required to maintain upper airway patency. During sleep the activity of these muscles is suppressed, and as a result individual with obstructive...
pubmed: sleep apnea
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Reducing the need for carbon dioxide monitoring in the investigation of paediatric sleep disordered breathing.
Related ArticlesReducing the need for carbon dioxide monitoring in the investigation of paediatric sleep disordered breathing. Eur Respir J. 2018 10;52(4): Authors: Trucco F, Bush A, Tan HL PMID: 30115615 [PubMed - indexed for MEDLINE]
pubmed: sleep apnea
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OSA patients: mind them in the preoperative screening!
Related ArticlesOSA patients: mind them in the preoperative screening! Minerva Anestesiol. 2018 07;84(7):874-875 Authors: Deflandre E, Degey S PMID: 29589424 [PubMed - indexed for MEDLINE]
pubmed: sleep apnea
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Proximal lateral approach to ultrasound-guided sciatic nerve block: where is the correct injection site?
Related ArticlesProximal lateral approach to ultrasound-guided sciatic nerve block: where is the correct injection site? Reg Anesth Pain Med. 2019 Aug 15;: Authors: Nielsen JK, Tranum-Jensen J, Boegevig S PMID: 31420367 [PubMed - as supplied by publisher]
anesth pain med
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Misconceptions on the injection level in the "proximal lateral approach" for sciatic nerve block.
Related ArticlesMisconceptions on the injection level in the "proximal lateral approach" for sciatic nerve block. Reg Anesth Pain Med. 2019 Aug 15;: Authors: Yoshida T, Nakamoto T PMID: 31420366 [PubMed - as supplied by publisher]
anesth pain med
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A Multi-Compartment Model Capturing the Pharmacokinetics of the Calcimimetic Cinacalcet.
Related ArticlesA Multi-Compartment Model Capturing the Pharmacokinetics of the Calcimimetic Cinacalcet. Cell Physiol Biochem. 2019;53(2):429-438 Authors: Schappacher-Tilp G, Fuertinger DH, Kotanko P Abstract BACKGROUND/AIMS: Chronic kidney disease-mineral bone disorder is a major complication affecting the vast majority of chronic kidney disease patients. A hallmark of the disorder is an altered parathyroid gland biology resulting in secondary hyperparathyroidism....
pubmed: "cell physiol bioche...
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