The Milk Allergy in Primary (MAP) Care guideline was first published in 2013 in this journal. MAP aimed to provide simple and accessible algorithms for UK clinicians in primary care, detailing all the steps be...
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Related ArticlesThe impact of oral appliance therapy with moderate mandibular advancement on obstructive sleep apnea and upper airway volume. Sleep Breath. 2019 Aug 10;: Authors: Pahkala R, Seppä J, Myllykangas R, Tervaniemi J, Vartiainen VM, Suominen AL, Muraja-Murro A Abstract PURPOSE: To find out if a moderate protrusion with a mandibular advancement device (MAD) can significantly increase the upper airway volume and, further, what signs and symptoms...
Related ArticlesValidation of noncontact cardiorespiratory monitoring using impulse-radio ultra-wideband radar against nocturnal polysomnography. Sleep Breath. 2019 Aug 10;: Authors: Kang S, Lee Y, Lim YH, Park HK, Cho SH, Cho SH Abstract PURPOSE: Polysomnography (PSG) is a standard diagnostic test for obstructive sleep apnea (OSA). However, PSG requires many skin-contacted sensors to monitor vital signs of patients, which may also hamper patients' sleep....
Related ArticlesFrequency and characteristic features of REM sleep without atonia. Clin Neurophysiol. 2019 Jul 27;130(10):1825-1832 Authors: Dijkstra F, Viaene M, Crosiers D, De Volder I, Cras P Abstract OBJECTIVES: Isolated REM sleep without atonia (iRSWA) is regarded as prodromal phase of REM sleep behavior disorder (RBD) and synucleinopathies. Other factors, however, have also been described to cause RSWA, including sleep apnea, antidepressants use...
Related ArticlesThe relationship between risk of obstructive sleep apnea and other sleep problems, depression, and anxiety in adolescents from a community sample. Psychiatry Res. 2019 Jul 31;280:112504 Authors: Park KM, Kim SY, Sung D, Kim H, Kim BN, Park S, Jung KI, Park MH Abstract Obstructive sleep apnea (OSA) is highly related to mental health problems, such as depression and anxiety. However, previous studies on OSA and depression and anxiety have...
Related ArticlesEducating Stroke/TIA Patients about Obstructive Sleep Apnea after Stroke: A Randomized Feasibility Study. J Stroke Cerebrovasc Dis. 2019 Aug 07;:104317 Authors: Dharmakulaseelan L, Kirolos N, Kamra M, Armesto-Heys A, Bouthillier C, Runions S, Linkewich E, Murray BJ, Boulos MI Abstract BACKGROUND: Obstructive sleep apnea (OSA) occurs in about 70% of stroke and transient ischemic attack (TIA) patients and is associated with poor function...
Related ArticlesAccuracy and utility of a pacemaker respiratory monitoring algorithm for the detection of obstructive sleep apnea in patients with atrial fibrillation. Sleep Med. 2019 Mar 07;: Authors: Gonçalves IS, Agostinho JR, Silva G, Guimarães T, Bernardes A, Santos I, Pinto P, Bárbara C, de Sousa J, Pinto FJ, Marques P Abstract INTRODUCTION: The usefulness and diagnostic value of new-generation pacemakers (PM) with enhanced monitoring capabilities...
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Related ArticlesA Novel Pyrazolopyrimidine Ligand of Human PGK1 and Stress Sensor DJ1 Modulates the Shelterin Complex and Telomere Length Regulation. Neoplasia. 2019 Aug 08;21(9):893-907 Authors: Bilsland AE, Liu Y, Turnbull A, Sumpton D, Stevenson K, Cairney CJ, Boyd SM, Roffey J, Jenkinson D, Keith WN Abstract Telomere signaling and metabolic dysfunction are hallmarks of cell aging. New agents targeting these processes might provide therapeutic opportunities,...
Related ArticlesEndocrine disrupters and possible contribution to pubertal changes. Best Pract Res Clin Endocrinol Metab. 2019 Jul 27;:101300 Authors: Fudvoye J, Lopez-Rodriguez D, Franssen D, Parent AS Abstract The onset of puberty strongly depends on organizational processes taking place during the fetal and early postnatal life. Therefore, exposure to environmental pollutants such as Endocrine disrupting chemicals (EDCs) during critical periods of...
Related ArticlesOrganophosphorus pesticide triazophos: A new endocrine disruptor chemical of hypothalamus-pituitary-adrenal axis. Pestic Biochem Physiol. 2019 Sep;159:91-97 Authors: Yang FW, Fang B, Pang GF, Ren FZ Abstract The organophosphorus pesticide, triazophos (TAP) was banned to use in agriculture in several countries due to its high toxicity. However, TAP was still widely used and frequently detected in foods. Recently, many studies reported...
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Related ArticlesDiagnosis of anterior cruciate ligament injury. Int J Surg. 2019 Aug 08;: Authors: Noordin S PMID: 31401325 [PubMed - as supplied by publisher]
Related ArticlesInvited Commentary "Short-term efficacy of transvaginal specimen extraction for right colon cancer based on propensity score matching: a retrospective cohort study". Int J Surg. 2019 Aug 08;: Authors: Asti E, Bonavina L PMID: 31401324 [PubMed - as supplied by publisher]
Related ArticlesInvited Commentary: 'Albumin-to-alkaline phosphatase ratio as a novel prognostic indicator for patients undergoing minimally invasive lung cancer surgery: A prospective propensity score matching study'. Int J Surg. 2019 Aug 08;: Authors: Abu-Talib M, Brown LR PMID: 31401323 [PubMed - as supplied by publisher]
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Related ArticlesSurgical approaches and results of treatment for hereditary paragangliomas. Best Pract Res Clin Endocrinol Metab. 2019 Jul 27;:101298 Authors: Iacobone M, Belluzzi A, Torresan F Abstract Paragangliomas (PGL) are rare neuroendocrine tumours; parasympathetic PGL are predominantly non-secreting and located at the skull base and neck, while sympathetic PGL are typically catecholamine-secreting and located at abdomino-pelvic level. Approximately...
Related ArticlesImaging characteristics of nasopharyngeal carcinoma for predicting distant metastasis. Clin Radiol. 2019 Aug 07;: Authors: Dumrongpisutikul N, Luangcharuthorn K Abstract AIM: To determine the imaging characteristics of nasopharyngeal carcinoma (NPC) that may be associated with increased risk of distant metastasis. MATERIALS AND METHODS: A total 164 patients with NPC were reviewed retrospectively. Patients were divided into the...
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Related ArticlesPlasmacytoid cells in salivary pleomorphic adenoma: an alternative interpretation of their immunohistochemical characteristics highlights function and capability for epithelial-mesenchymal transition. Oral Surg Oral Med Oral Pathol Oral Radiol. 2019 Feb 07;: Authors: Koutlas IG, Dolan M, Lingen MW, Argyris PP Abstract OBJECTIVES: Plasmacytoid cells (PLCs) in salivary pleomorphic adenoma (SPA) are regarded as modified neoplastic myoepithelia...
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Related ArticlesDirect electrophysiological mapping of human pitch-related processing in auditory cortex. Neuroimage. 2019 Aug 08;:116076 Authors: Gander PE, Kumar S, Sedley W, Nourski KV, Oya H, Kovach CK, Kawasaki H, Kikuchi Y, Patterson RD, Howard MA, Griffiths TD Abstract This work sought correlates of pitch perception, defined by neural activity above the lower limit of pitch (LLP), in auditory cortical neural ensembles, and examined their topographical...
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Related ArticlesVestibular testing in children with severe-to-profound hearing loss. Int J Pediatr Otorhinolaryngol. 2019 Jul 29;125:201-205 Authors: Kotait MA, Moaty AS, Gabr TA Abstract Many studies showed that children with sensorineural hearing loss (SNHL) have possible vestibular affection which is related to the severity of cochlear pathology. OBJECTIVES: this work is designed to evaluate vestibular function in children with congenital...
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Related ArticlesLong-term treatment outcomes of patients with primary optic nerve sheath meningioma treated with stereotactic radiotherapy. J Clin Neurosci. 2019 Aug 07;: Authors: Ratnayake G, Oh T, Mehta R, Hardy T, Woodford K, Haward R, Ruben JD, Dally MJ Abstract We analysed the long-term outcomes of patients with primary optic nerve sheath meningioma (ONSM) treated with stereotactic radiotherapy (SRT). 26 patients with primary ONSM were treated with...
Related ArticlesPain control after aneurysmal subarachnoid hemorrhage: A contemporary literature review. J Clin Neurosci. 2019 Aug 07;: Authors: Rasouli J, Watson C, Yaeger K, Ladner T, Kellner C, Dangayach NS PMID: 31401000 [PubMed - as supplied by publisher]
Related ArticlesIntrathecal baclofen trial using a temporary indwelling intrathecal catheter - A single institution experience. J Clin Neurosci. 2019 Aug 07;: Authors: Vats A, Amit A, Cossar M, Bhatt P, Cozens A Abstract Intrathecal baclofen infusion trial is a sophisticated tool for selecting patients for permanent intra thecal baclofen infusion therapy We report our clinical experience of fifteen patients with refractory spasticity who underwent a...
Related ArticlesDeterioration of postural deformity in Parkinson's disease patients with punding and hobbyism. J Clin Neurosci. 2019 Aug 07;: Authors: Aoki R, Shiraishi M, Mikami K, Kamo T Abstract This study aimed to examine whether worsening of postural deformities is seen in Parkinson's disease (PD) patients who exhibit the behavioral disorders punding or hobbyism (P-H), which involve maintaining the same poor posture. The subjects were 80 patients...
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Related ArticlesLong-Term Radiotherapy-Induced Cardiac Complications: A Case Report. Am J Case Rep. 2019 Aug 11;20:1182-1188 Authors: Báez-Ferrer N, Izquierdo-Gómez MM, Beyello-Belkasem C, Jorge-Pérez P, García-González MJ, Ferrer-Hita JJ, De la Rosa-Hernández A, García-Niebla J, Lacalzada-Almeida J Abstract BACKGROUND Tumor disease has improved survival due to therapeutic advances and early diagnosis. However, anti-neoplastic treatment involves generating...
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Related ArticlesNovel anticancer PdII complexes: The effect of the conjugation of transferrin binding peptide and the nature of halogen coordinated on antitumor activity. J Inorg Biochem. 2019 Jun 27;199:110754 Authors: Teles CM, Lammoglia LC, Juliano MA, Ruiz ALTG, Candido TZ, de Carvalho JE, Lima CSP, Abbehausen C Abstract A series of PdII complexes with bis-(2-pyridylmethyl)glycine as a ligand of formula [PdX(bis-(2-pyridylmethyl)glycine)] where X = Cl,...
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Related ArticlesIdarubicin, cytarabine, and nivolumab in patients with newly diagnosed acute myeloid leukaemia or high-risk myelodysplastic syndrome: a single-arm, phase 2 study. Lancet Haematol. 2019 Aug 07;: Authors: Ravandi F, Assi R, Daver N, Benton CB, Kadia T, Thompson PA, Borthakur G, Alvarado Y, Jabbour EJ, Konopleva M, Takahashi K, Kornblau S, DiNardo CD, Estrov Z, Flores W, Basu S, Allison J, Sharma P, Pierce S, Pike A, Cortes JE, Garcia-Manero G, Kantarjian...
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Related ArticlesThyroid Surgery: Whose Domain Is It? Adv Ther. 2019 Aug 10;: Authors: Zbären P, Shah JP, Randolph GW, Silver CE, Olsen KD, Shaha AR, Zafereo M, Kowalski LP, Suarez C, Sanabria A, Vander Poorten V, Nixon I, Rinaldo A, Ferlito A Abstract In the United States of America (US), most departments of otorhinolaryngology head and neck surgery have been performing thyroid surgery for many years. In contrast to the US, thyroid surgery is still dominated...
Related ArticlesThe impact of oral appliance therapy with moderate mandibular advancement on obstructive sleep apnea and upper airway volume. Sleep Breath. 2019 Aug 10;: Authors: Pahkala R, Seppä J, Myllykangas R, Tervaniemi J, Vartiainen VM, Suominen AL, Muraja-Murro A Abstract PURPOSE: To find out if a moderate protrusion with a mandibular advancement device (MAD) can significantly increase the upper airway volume and, further, what signs and symptoms...
Related ArticlesValidation of noncontact cardiorespiratory monitoring using impulse-radio ultra-wideband radar against nocturnal polysomnography. Sleep Breath. 2019 Aug 10;: Authors: Kang S, Lee Y, Lim YH, Park HK, Cho SH, Cho SH Abstract PURPOSE: Polysomnography (PSG) is a standard diagnostic test for obstructive sleep apnea (OSA). However, PSG requires many skin-contacted sensors to monitor vital signs of patients, which may also hamper patients' sleep....
Related ArticlesA modified protocol of mandibular osteoradionecrosis induction in rats with external beam radiation therapy. Clin Oral Investig. 2019 Aug 10;: Authors: Yamasaki MC, Roque-Torres GD, Peroni LV, Nascimento EHL, Salmon B, Oliveira ML, Freitas DQ, Correr-Sobrinho L Abstract OBJECTIVE: To propose a modified protocol of mandibular osteoradionecrosis induction in rats with external beam radiation therapy. MATERIAL AND METHODS: A total...
Related ArticlesRemoval of an inhaled stoma button distal to a reactionary tracheal stenosis: a difficult airway case. BMJ Case Rep. 2019 Aug 10;12(8): Authors: Gray G, Adams M, Black M, Sidhu P Abstract We present the complex and rare case of an inhaled stoma button causing proximal tracheal stenosis in a laryngectomy patient. The patient was unaware he had inhaled his button and presented with increasing shortness of breath and noisy breathing. In...
Related ArticlesVestibular testing in children with severe-to-profound hearing loss. Int J Pediatr Otorhinolaryngol. 2019 Jul 29;125:201-205 Authors: Kotait MA, Moaty AS, Gabr TA Abstract Many studies showed that children with sensorineural hearing loss (SNHL) have possible vestibular affection which is related to the severity of cochlear pathology. OBJECTIVES: this work is designed to evaluate vestibular function in children with congenital...
Related ArticlesMultidisciplinary management of giant cervicothoracic cutaneous squamous cell carcinoma. Int J Surg Case Rep. 2019 Aug 01;61:294-297 Authors: López PA, Pedraza M, Moreno A, García O, Buitrago R, Mogollon G, Fory L, Conrado H Abstract INTRODUCTION: Cutaneus squamous cell carcinoma (SCC) is the second most common type of nonmelanoma skin cancer. SCC is a malignant neoplasm of the skin characterized by aberrant proliferation of keratinocytes....
Related ArticlesComparison of methods to isolate proteins from extracellular vesicles for mass spectrometry-based proteomic analyses. Anal Biochem. 2019 Aug 08;:113390 Authors: Subedi P, Schneider M, Philipp J, Azimzadeh O, Metzger F, Moertl S, Atkinson MJ, Tapio S Abstract Extracellular vesicles (EVs) are cell-derived membrane-bound organelles that have generated interest as they reflect the physiological condition of their source. Mass spectrometric...
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Related ArticlesEmergence of Fungal-Like Organisms: Prototheca. Mycopathologia. 2019 Aug 10;: Authors: Kano R Abstract The genus Prototheca consists of achlorophyllic algae that are ubiquitous in the environment and animal intestines. However, this organism has forfeited its photosynthetic ability and switched to parasitism. In 1894, Krüger described two microorganisms isolated in Germany from mucous flux of Tilia and Ulmus spp., namely Prototheca moriformis...
Related ArticlesA 1-Year Prospective French Nationwide Study of Emergency Hospital Admissions in Children and Adults with Primary Immunodeficiency. J Clin Immunol. 2019 Aug 10;: Authors: Coignard-Biehler H, Mahlaoui N, Pilmis B, Barlogis V, Brosselin P, De Vergnes N, Debré M, Malphettes M, Frange P, Catherinot E, Pellier I, Durieu I, Perlat A, Royer B, Le Quellec A, Jeziorski E, Fischer A, Lortholary O, CEREDIH French PID study group, Aaron L, Adoue D, Aguilar C, Aladjidi...
Related ArticlesSensitivity of point-of-care testing C reactive protein and procalcitonin to diagnose urinary tract infections in Dutch nursing homes: PROGRESS study protocol. BMJ Open. 2019 Aug 10;9(8):e031269 Authors: Kuil SD, Hidad S, Fischer JC, Harting J, Hertogh CM, Prins JM, van Leth F, de Jong MD, Schneeberger C Abstract INTRODUCTION: Suspected urinary tract infection (UTI) ranks among the most common reasons for antibiotic use in nursing homes....
Related ArticlesPathways to optimising antibiotic use in rural China: identifying key determinants in community and clinical settings, a mixed methods study protocol. BMJ Open. 2019 Aug 10;9(8):e027819 Authors: Zhao L, Kwiatkowska RM, Chai J, Cabral C, Chen M, Bowker K, Coope C, Shen J, Shen X, Cheng J, Feng R, Kadetz P, MacGowan A, Oliver I, Hickman M, Wang D, Lambert H Abstract INTRODUCTION: This study aims to investigate patterns of antibiotic treatment-seeking,...
Related ArticlesThe high genetic similarity between rhinoviruses and enteroviruses remains as a pitfall for molecular diagnostic tools: A three-year overview. Infect Genet Evol. 2019 Aug 08;: Authors: Andrés C, Piñana M, Vila J, Esperalba J, Trejo-Zahínos J, Codina MG, Martín MC, Fuentes F, Rubio S, Pumarola T, Antón A Abstract BACKGROUND: Enteroviruses (EVs) and rhinoviruses (RVs) belong to the Enterovirus genus within the Picornaviridae family, and...
Related ArticlesTesting for viral infections in severe lower respiratory tract infections; the unpredictable effects of diagnostic certainty. Clin Microbiol Infect. 2019 Aug 08;: Authors: Vos L, Oosterheert JJ Abstract Testing for viral infections in severe lower respiratory tract infections; the unpredictable effects of diagnostic certainty.PMID: 31401176 [PubMed - as supplied by publisher]
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Related ArticlesOverexpression of SNORA21 suppresses tumorgenesis of gallbladder cancer in vitro and in vivo. Biomed Pharmacother. 2019 Aug 08;118:109266 Authors: Qin Y, Zhou Y, Ge A, Chang L, Shi H, Fu Y, Luo Q Abstract BACKGROUND: Gallbladder cancer (GBC) ranks fifth in the most common malignancy of the gastrointestinal tract worldwide. It is reported many small nucleolar RNAs (SNORNs) could regulate the progression of GBC. To identify potential therapeutic...
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Related ArticlesSleep quality assessment in chronic rhinosinusitis patients submitted to endoscopic sinus surgery: a meta-analysis. Braz J Otorhinolaryngol. 2019 Jul 29;: Authors: Guttemberg MDA, Mata FAFD, Nakanishi M, de Andrade KRC, Pereira MG Abstract INTRODUCTION: Chronic rhinosinusitis can lead to poor sleep quality in affected individuals. Endoscopic nasal surgery has been indicated for patients with chronic rhinosinusitis, resulting in improved...
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Related ArticlesDuodenal GI stromal tumors: Is radical resection necessary? J Surg Oncol. 2019 Aug 10;: Authors: Uppal A, Wang M, Fischer T, Goldfarb M Abstract BACKGROUND AND OBJECTIVES: Duodenal gastrointestinal stromal tumors (GISTs) are rare tumors that pose a surgical challenge, and long-term outcomes after resection have not been detailed outside of small case series. This study uses the National Cancer Database (NCDB) to examine the determinants...
Related ArticlesThe grandfather's fever. Clin Rheumatol. 2019 Aug 10;: Authors: Ricci P, Stella A, Settimo E, Passerini F, Minerva F, Belfiore A, Palmieri VO, Pugliese S, Scaccianoce G, Portincasa P Abstract An 86-year-old Caucasian man had prior episodes of fever (up to 38 °C), mild abdominal pain, tachycardia, and malaise in the last 3 months, lasting 2-3 days. He never suffered from abdominal or chest pain, rash, or arthralgia. Major causes of fever...
Related ArticlesRare cause of pulmonary hypertension - pulmonary tumour thrombotic microangiopathy. BMJ Case Rep. 2019 Aug 09;12(8): Authors: O'Brien J, Jones N, Horrigan M, Al-Kaisey AM Abstract Pulmonary tumour thrombotic microangiopathy (PTTA) is a rare but lethal cause of pulmonary hypertension (PHT). Its underlying mechanism is believed to be fibrocellular intimal proliferation and microthrombosis. It has been reported in association with gastric...
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Related ArticlesIdarubicin, cytarabine, and nivolumab in patients with newly diagnosed acute myeloid leukaemia or high-risk myelodysplastic syndrome: a single-arm, phase 2 study. Lancet Haematol. 2019 Aug 07;: Authors: Ravandi F, Assi R, Daver N, Benton CB, Kadia T, Thompson PA, Borthakur G, Alvarado Y, Jabbour EJ, Konopleva M, Takahashi K, Kornblau S, DiNardo CD, Estrov Z, Flores W, Basu S, Allison J, Sharma P, Pierce S, Pike A, Cortes JE, Garcia-Manero G, Kantarjian...
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Publication date: Available online 11 August 2019Source: Pathology - Research and PracticeAuthor(s): Wen-Xiao Chai, Li-Guo Sun, Fu-Hong Dai, Hong-Sheng Shao, Ning-Gang Zheng, Hong-Yi CaiAbstractThe aim of this study was to investigate whether PRRX2 may regulate the liver metastasis of colon cancer via the Wnt/β-catenin signaling pathway. PRRX2 and β-catenin in patients with the liver metastases of colon cancer was detected by immunochemistry. Colon cancer cells (CT-26 and CMT93) were divided into...
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Related ArticlesPretreatment low prognostic nutritional index and low albumin-globulin ratio are predictive for overall survival in nasopharyngeal cancer. Eur Arch Otorhinolaryngol. 2019 Aug 10;: Authors: Gundog M, Basaran H Abstract PURPOSE: We designed this retrospective study to identify predictive value of prognostic nutritional index (PNI) and albumin-globulin ratio (AGR) in nasopharyngeal cancer patients (NPC). METHODS: 95 non-metastatic...
19h
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Related ArticlesMorphometric development of the tongue in fetal cadavers. Surg Radiol Anat. 2019 Aug 10;: Authors: Dursun A, Kastamonı Y, Kacaroglu D, Yuzbasıoglu N, Ertekın T Abstract PURPOSE: The tongue is a specific organ for the sense of taste. It consists of the striated muscle and mucous membrane. Furthermore, it helps the functions of speech, chewing, and swallowing. In this study, we aimed to reveal some morphometric properties of the tongue...
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Related Articlesα-Arbutin Protects Against Parkinson's Disease-Associated Mitochondrial Dysfunction In Vitro and In Vivo. Neuromolecular Med. 2019 Aug 10;: Authors: Ding Y, Kong D, Zhou T, Yang ND, Xin C, Xu J, Wang Q, Zhang H, Wu Q, Lu X, Lim K, Ma B, Zhang C, Li L, Huang W Abstract Parkinson's disease (PD), the most common neurodegenerative movement disorder, is characterized by the progressive loss of dopaminergic neurons in substantia nigra. The...
Related ArticlesTargeting TRPV1 on cellular plasticity regulated by Ovol 2 and Zeb 1 in hepatocellular carcinoma. Biomed Pharmacother. 2019 Aug 08;118:109270 Authors: Xie C, Liu G, Li M, Fang Y, Qian K, Tang Y, Wu X, Lei X, Li X, Liu Q, Liu G, Liu J, Zhang Y, Huang Z, Hu Z, Cao Z, Hu J, Huang S, Zhong D, Huang J, Wu F, Wang J, Mori M, Yamamoto H, Wang J, Xu X Abstract The landscape of cellular plasticity and sources with relevant niche signals in hepatocellular...
Related ArticlesDirect electrophysiological mapping of human pitch-related processing in auditory cortex. Neuroimage. 2019 Aug 08;:116076 Authors: Gander PE, Kumar S, Sedley W, Nourski KV, Oya H, Kovach CK, Kawasaki H, Kikuchi Y, Patterson RD, Howard MA, Griffiths TD Abstract This work sought correlates of pitch perception, defined by neural activity above the lower limit of pitch (LLP), in auditory cortical neural ensembles, and examined their topographical...
Related ArticlesNMDA receptor modulation of glutamate release in activated neutrophils. EBioMedicine. 2019 Aug 08;: Authors: Del Arroyo AG, Hadjihambi A, Sanchez J, Turovsky E, Kasymov V, Cain D, Nightingale TD, Lambden S, Grant SGN, Gourine AV, Ackland GL Abstract BACKGROUND: Neutrophil depletion improves neurologic outcomes in experimental sepsis/brain injury. We hypothesized that neutrophils may exacerbate neuronal injury through the release of neurotoxic...
Related ArticlesReinserting Physiology into Cardiac Mapping Using Omnipolar Electrograms. Card Electrophysiol Clin. 2019 Sep;11(3):525-536 Authors: Magtibay K, Porta-Sánchez A, Haldar SK, Deno DC, Massé S, Nanthakumar K Abstract Omnipolar electrograms (EGMs) make use of biophysical electric fields that accompany activation along the surface of the myocardium. A grid-like electrode array provides bipolar signals in orthogonal directions to deliver catheter-orientation-independent...
Related ArticlesAn Anesthesiologist in the Space Race: The Life and Career of Dr. Cloid D. Green. J Anesth Hist. 2019 Apr;5(2):44-48 Authors: Coleman ML Abstract The space race began in the summer of 1955 when the United States and the Soviet Union pledged to launch artificial satellites. The race culminated in 1969 when the United States landed the first humans on the moon. After completing his training in anesthesiology, Dr. Cloid Green forged his...
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Publication date: Available online 11 August 2019Source: Photodiagnosis and Photodynamic TherapyAuthor(s): Thaila Quatrini Corrêa, Kate Cristina Blanco, Jennifer Machado Soares, Natalia Mayumi Inada, Cristina Kurachi, Marjorie de Assis Golim, Elenice Deffune, Vanderlei Salvador BagnatoAbstractBackgroundBlood can be the target of bacterial, fungal, viral and parasitic contamination. Blood bags used in hemotherapy for transfusion of erythrocytes, platelets, and plasma are targets of contamination,...
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Abstract To retrospectively characterize the molecular features of Non-Small Cell Lung Carcinomas (NSCLC) with peritoneal carcinomatosis (PC), clinicopathological data of 12 patients diagnosed with NSCLC and PC between 2007 and 2016 were collected. Immunohistochemistry and Next Generation Sequencing (NGS) were performed on cases with available material. PC was the initial presentation of NSCLC in 17% of the cases. Overall, patients with PC displayed a poor median survival of 12 weeks....
Abstract Carbohydrate response element binding protein (ChREBP) is a glucose-sensing transcription factor that mediates the induction of glycolytic and lipogenic genes in response to glucose. We investigated the expression patterns of ChREBP and glucose transporters (GLUTs) in human hepatocellular carcinoma (HCC) and their association with HCC progression. ChREBP, GLUT2 and GLUT1 immunohistochemistry were performed on liver tissue array containing normal liver tissue, HCC adjacent...
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Abstract Background Progressive telomere shortening with age or chronic inflammation may lead to genomic instability that characterizes the early stage of carcinogenesis. Certain risk factors, such as drinking alcoholic beverages, or smoking, predispose the oral mucosa to squamous cell carcinoma. The ADH1B and ALDH2 genotypes can influence the risk of cancer due to alcohol drinking. In the present study, we analyzed chromosomal instability due to telomere shortening in the oral mucosa in relation...
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Abstract Purpose Graves’ disease (GD) can present as an isolated disease (iGD) or in association with other autoimmune diseases (aGD). The aim of this study, performed in two Endocrine referral centers settled in different geographical areas of Italy, was to compare the anthropometric, clinical, and biochemical phenotype of iGD patients with that of the aGD ones. Methods ...
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Abstract In 1997, deShazo et al.1, 2 conducted a literature review and proposed a novel classification of fungal rhinosinusitis. The authors divided fungal rhinosinusitis into invasive and noninvasive forms. The classification included acute and chronic invasive fungal rhinosinusitis (AIFRS and CIFRS), chronic granulomatous fungal rhinosinusitis, fungus ball, and allergic fungal rhinosinusitis (AFRS). Nowadays, the classification proposed by deShazo et al. is widely accepted and is frequently cited...
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Abstract Purpose To gain insight into the patient characteristics of surgically treated hydrocephalus in the Netherlands, we report the first data from the Dutch Quality Registry NeuroSurgery (QNRS) database for infants with hydrocephalus requiring surgical intervention. Methods We used the prospectively gathered database concerning infants ≤ 2 years of age...
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Publication date: Available online 12 August 2019Source: Academic RadiologyAuthor(s): Ramkumar Krishnamurthy, Benjamin L. Thompson, Anand Shankar, Cheryl E. Gariepy, Carol J. Potter, Bonita R. Fung, Houchun H. HuRationale and ObjectivesWe describe our experience in measuring parenchyma stiffness across the liver Couinaud segments in lieu of the conventional practice of using a single slice-wise “global” region-of-interest. We hypothesize that the heterogeneous nature of fibrosis can lead to regional...
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Phospholipase D1 (PLD1) is dominantly demonstrated in immature GCT cells characterized by electron‐lucent granules in the mouse submandibular gland. PLD1 is greater in females and is suppressed by testosterone. It is suggested that PLD1 is involved in the signaling for secretion of immature GCT cells and influences differentiation of these cells, probably through their own secretory substances. Abstract To clarify the signal transduction mechanism in the differentiation and secretion of salivary...
The numbering of the pharyngeal arches in humans, and other amniotes, should simply be from anterior to posterior, 1, 2, 3, 4 and 5. Abstract The pharyngeal arches are a prominent and significant feature of vertebrate embryos. These are visible as a series of bulges on the lateral surface of the embryonic head. In humans, and other amniotes, there are five pharyngeal arches numbered 1, 2, 3, 4 and 6; note the missing ‘5’. This is the standard scheme for the numbering of these structures, and it...
Theoretical models of fascia layers. (A) The Stecco human model. (B) Horse model. (C) Dog model. DAT, deep adipose tissue; DE, dermis; DF+EM, deep fascia inclusive epimysium; ED, epidermis; HY, hypodermis; MU, muscle; PL, papillary layer of dermis; RL, reticular layer of dermis; SAT, superficial adipose tissue; SF, superficial fascia; SF+CT,superficial fascia inclusive m. cutaneus trunci; SH, superficial compartment of hypodermis; TL, third layer of dermis. Abstract Fascia in the veterinary sciences...
Enamel rods in rodent incisors are arranged as stacked rows with alternating tilt angles across the transverse plane of the tooth. This study quantifies row patterns to determine if the layering of the rows and the alternating tilt angles are uniform or more irregular and complex in arrangement. The results indicated considerable diversity in row lengths, row tilts and 2D spatial row arrangements both within and between rows. Abstract The 2D arrangement of rows of enamel rods with alternating (decussating)...
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Giant cell arteritis is a granulomatous inflammation of large and medium‐sized arteries, occurring predominantly in older women. In this case, a 76‐year‐old woman was hospitalized for examination because of a high C‐reactive protein (CRP) level, but nothing remarkable was found on thoracicoabdominal computed tomography (CT) or head magnetic resonanse imaging (MRI). On the 46th day from the first visit, she died suddenly due to cardiac tamponade. On pathological autopsy, we found the cause of death...
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Abstract In 1997, deShazo et al.1, 2 conducted a literature review and proposed a novel classification of fungal rhinosinusitis. The authors divided fungal rhinosinusitis into invasive and noninvasive forms. The classification included acute and chronic invasive fungal rhinosinusitis (AIFRS and CIFRS), chronic granulomatous fungal rhinosinusitis, fungus ball, and allergic fungal rhinosinusitis (AFRS). Nowadays, the classification proposed by deShazo et al. is widely accepted and is frequently cited...
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Abstract Purpose Central sleep apnea (CSA) is a highly common comorbidity in heart failure (HF) patients and is known to deteriorate quality of life and prognosis. Effective treatment options are scarce. Transvenous phrenic nerve stimulation (PNS) has been shown to be effective and safe in CSA treatment in HF. However, lead implantation may be difficult or fail due to anatomical or technical challenges. We report novel and innovative approaches...
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Abstract Tyrosine kinase inhibitor (TKI) administration after allogeneic hematopoietic stem cell transplantation (HSCT) may carry a survival benefit in Philadelphia chromosome positive acute lymphoblastic leukemia (Ph+ ALL). Therefore, we investigated whether TKI prophylaxis for negative‐minimal residual disease (MRD) after HSCT would improve their outcomes in this nationwide retrospective cohort study. We included patients with Ph+ ALL who underwent their first allogeneic HSCT between 2001 and...
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Abstract Introduction Gastrostomy insertion either via radiological (radiologically inserted gastrostomy, RIG) or endoscopic (percutaneous endoscopic gastrostomy, PEG) approaches are widely practiced throughout Australia. The purpose of this study was to compare outcomes of inserted tubes and cost evaluation by both methods. Methods A retrospective cohort study conducted on all‐cause gastrostomy insertions at a quaternary Australian Hospital, Royal Brisbane and Womens' Hospital (RBWH) between...
Abstract Introduction/Purpose To assist radiation oncologists in determining the elective nodal CTV for biliary tract cancer, we aimed to provide the rules for selection of the CTV for each subsite of biliary tract with respect to the pT stage, based on the analysis of the incidence and location of metastatic lymph nodes. Methods Systematic review and meta‐analysis was performed to determine the rate of pathological nodal involvement of each individual lymph node station (LNS) as a function...
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Background Erectile dysfunction is a major complication of diabetes mellitus. Adipose-derived stem cells (ADSCs) have attracted much attention as a promising tool for the treatment of diabetes mellitus-induced erectile dysfunction (DMED). Inducible nitric oxide synthase (iNOS) plays an important role in protecting penile tissues from fibrosis. The aim of this study was to determine the efficacy of ADSCs overexpressing iNOS on DMED in rats. Methods ADSCs were isolated and infected with...
Systemic insecticides such as neonicotinoids and sulfoximines can be present in the nectar and pollen of treated crops, through which foraging bees can become acutely exposed. Research has shown that acute, field realistic dosages of neonicotinoids can negatively influence bee learning and memory, with potential consequences for bee behaviour. As legislative reassessment of neonicotinoid use occurs globally, there is an urgent need to understand the potential risk of other systemic insecticides....
To ease nutritional stress on managed as well as native bee populations in agricultural habitats, agro-environmental protection schemes aim to provide alternative nutritional resources for bee populations during times of need. However, such efforts have so far focused on quantity (supply of flowering plants) and timing (flower-scarce periods) while ignoring the quality of the two main bee relevant flower-derived resources (pollen and nectar). As a first step to address this issue we have compiled...
Background Some genera of the family Symbiodiniaceae establish mutualistic endosymbioses with various marine invertebrates, with coral being the most important ecologically. Little is known about the biochemical communication of this association and the perception and translation of signals from the environment in the symbiont. However, specific phosphorylation/dephosphorylation processes are fundamental for the transmission of external signals to activate physiological responses....
We describe a new species of terrestrial frog of the genus Noblella from the eastern versants of the Ecuadorian Andes in the upper Pastaza watershed. Noblella naturetrekii sp. n. differs from its Ecuadorian congeners by the presence of a differentiated tympanic membrane and a weakly defined tympanic annulus, and eyelids with rounded tubercles. In addition, the new species is characterized by its blackish–dark brown ventral coloration scattered with little white dots and the absence of papillae at...
Background Hibiscus hamabo Sieb. et Zucc. is a semi-mangrove plant used for the ecological restoration of saline-alkali land, coastal afforestation and urban landscaping. The genetic transformation H. hamabo is currently inefficient and laborious, restricting gene functional studies on this species. In plants, virus-induced gene silencing provides a pathway to rapidly and effectively create targeted gene knockouts for gene functional studies. ...
Ocean warming threatens the functioning of coral reef ecosystems by inducing mass coral bleaching and mortality events. The link between temperature and coral bleaching is now well-established based on observations that mass bleaching events usually occur when seawater temperatures are anomalously high. However, times of high heat stress but without coral bleaching are equally important because they can inform an understanding of factors that regulate temperature-induced bleaching. Here, we investigate...
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