Biological pathways underlying severe asthma can be divided broadly into T2hi and T2low, with T2hi having a greater presence of type 2 innate lymphoid and helper T cells, the cytokines interleukin (IL)-4, IL-5, IL-13 and eosinophils, while T2low may show lack of inflammation or neutrophil predominance driven by Th1 and Th17 cells and the related cytokines IL-17 and interferon-γ.1-3 In the past few years, more targeted biologic therapies have become available which specifically block T2 pathways and...
To review the cost-effectiveness of food allergy management strategies.
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