Novel treatment for mild and moderate VPI using implantable AlloDerm for posterior pharyngeal wall augmentation: Case series and review of surgical techniques
Author links open overlay panelKunal R.ShettyaLibby M.WardaJessica R.LevibGregoryGrilloneb
a
Boston University School of Medicine, 72 East Concord St., Boston, MA 02118, USA
b
Department of Otolaryngology–Head and Neck Surgery, Boston University Medical Center, 830 Harrison Avenue, Boston, MA 02118, USA
Received 31 July 2019, Available online 5 August 2019.

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https://doi.org/10.1016/j.amjoto.2019.08.005Get rights and content
Abstract
Purpose
Mild and moderate velopharyngeal insufficiency is a relatively common structural defect of the velopharyngeal sphincter that occurs congenitally or secondarily to various medical conditions resulting in speech inadequacy. Currently, multiple surgical methods exist to treat mild and moderate velopharyngeal insufficiency; however, the revision rates are high and the outcomes are variable. This case series describes a novel technique using implantable AlloDerm to repair the posterior pharyngeal wall to treat mild and moderate velopharyngeal insufficiency.

Materials and methods
This paper presents four patients with mild or moderate velopharyngeal insufficiency who were treated with implantable AlloDerm in the posterior pharyngeal wall at a large, safety-net hospital in New England from 2000 to 2019.

Results
There were sufficient follow-up data in three of these patients. All three reported subjective improvements in symptoms after the procedure. One patient had implant extrusion one month following the procedure with subsequent removal.

Conclusion
Ultimately, implantable AlloDerm for posterior pharyngeal wall augmentation is a useful, low risk method for treating mild to moderate velopharyngeal insufficiency.

Keywords
AlloDerm implantVelopharyngeal insufficiencyVPICleft palatePharynxSurgical repair