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Δευτέρα 24 Ιουνίου 2019

ORL


Rapamycin Protects Spiral Ganglion Neurons from Gentamicin-Induced Degeneration In Vitro
Abstract Gentamicin, one of the most widely used aminoglycoside antibiotics, is known to have toxic effects on the inner ear. Taken up by cochlear hair cells and spiral ganglion neurons (SGNs), gentamicin induces the accumulation of reactive oxygen species (ROS) and initiates apoptosis or programmed cell death, resulting in a permanent and irreversible hearing loss. Since the survival of SGNs is specially required for cochlear implant, new procedures that prevent SGN cell loss...
Latest Results for Journal of the Association for Research in Otolaryngology
12h
The Size of Internal Auditory Canal Diverticula Is Unrelated to Degree of Hearing Loss
Objectives To explore the relationship between hearing loss and the internal auditory canal (IAC) diverticula. To determine whether diverticula exist within or medial to the otic capsule and the prevalence in a control population. Methods Retrospective review of adult patients with radiologic evidence of an IAC diverticulum, no evidence of otosclerosis, and audiometric testing. Analyzed degree of hearing loss and width, length, height, and volume of diverticulum. Hounsfield unit (HU) measurements...
The Laryngoscope
15h
Rapamycin Protects Spiral Ganglion Neurons from Gentamicin-Induced Degeneration In Vitro
Abstract Gentamicin, one of the most widely used aminoglycoside antibiotics, is known to have toxic effects on the inner ear. Taken up by cochlear hair cells and spiral ganglion neurons (SGNs), gentamicin induces the accumulation of reactive oxygen species (ROS) and initiates apoptosis or programmed cell death, resulting in a permanent and irreversible hearing loss. Since the survival of SGNs is specially required for cochlear implant, new procedures that prevent SGN cell loss...
Journal of the Association for Research in Otolaryngology
11h
The usefulness of abscess tonsillectomy followed by intraoral drainage for parapharyngeal abscess concomitant with peritonsillar abscess in the elderly
Publication date: Available online 23 June 2019Source: Auris Nasus LarynxAuthor(s): Junichiro Ohori, Hiroyuki Iuchi, Hiromi Nagano, Mizuo Umakoshi, Hirohisa Matsuzaki, Yuichi KuronoAbstractParapharyngeal abscess (PPA) may cause life-threatening complications and peritonsillar abscess (PTA) and tonsillitis frequently precede PPA. The optimal management of PPA caused by PTA has been the subject of debate with respect to the surgical approach. We present three cases of PPA concomitant with PTA in elderly...
Auris Nasus Larynx
16h
Opioid prescribing practices following elective surgery in Otolaryngology-Head & Neck Surgery
Prescription opioid abuse has become a major issue across the world and especially in North America. Canada has the second highest number of opioid prescriptions per capita in the world, second only to the Uni...
Journal of Otolaryngology - Head & Neck Surgery
3h
Segmental tracheal resection (nine rings) and reconstruction for carcinoma showing thymus‐like differentiation (CASTLE) of the thyroid
Abstract Background Tumors invading the trachea are rare, and although literature often suggests five tracheal rings as the maximum limit of tracheal resection with primary closure, longer tracheal resections and primary closure are possible in many patients. One such locally invasive tumor with propensity for tracheal invasion is carcinoma showing thymic‐like differentiation (CASTLE) of the thyroid. Methods A 53‐year‐old woman presents with a 2‐year history of hoarseness, newly diagnosed...
Head & Neck
14h

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