Multiphase Contrast-Enhanced CT Imaging Features of Salivary Duct Carcinoma: Differentiation from Other Salivary Gland Malignancies Publication date: Available online 6 June 2019 Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Author(s): Wen-li Wu, Cheng-long Wang, Dan Li, Jin Luo, Jun-yong Ye, Sheng-sheng Xu Abstract Objective To investigate the CT imaging features of salivary duct carcinoma (SDC) with multiphase contrast-enhanced CT (CECT) scanning and to compare them to mucoepidermoid carcinoma (MEC), adenoid cystic carcinoma (ACC), and acinic cell carcinoma (AcCC). Study design A total of 63 patients with histologically diagnosed salivary gland malignancies underwent preoperative multiphase CECT. Clinical information, location, size, mass pattern, enhancement pattern, borders, invasion of adjacent tissues, and lymph node metastasis were evaluated. CT number attenuation patterns were calculated. Results SDCs were significantly more common in males and in the parotid gland (p≤0.018). They were more likely to invade into adjacent tissues and metastasize to lymph nodes (p≤0.032). Six SDCs (66.7%) had comedonecrosis as detected on histopathological examination, and 3 lesions presented cribriform necrosis on CECT. CT numbers during delayed-phase scanning were significantly higher in SDC than ACC (p=0.031). Significant differences were discovered between MEC and ACC for CT numbers during arterial-phase scanning (p=0.047) and in the ratio of CT numbers (p=0.018). Conclusion SDC exhibits some specific CT features, and multiphase CECT imaging is useful in the differential diagnosis of salivary gland malignancies.