Allergology International,

Cysteinyl leukotriene metabolism of human eosinophils in allergic disease

Publication date: Available online 24 June 2019Source: Allergology InternationalAuthor(s): Jun Miyata, Koichi Fukunaga, Yusuke Kawashima, Osamu Ohara, Makoto AritaAbstractEosinophils are multifaceted immune cells with diverse functions that enhance allergic inflammation. Cysteinyl leukotrienes (cys-LTs), mainly synthesized in eosinophils, are a class of inflammatory lipid mediators produced via multiple enzymatic reactions from arachidonic acid. Multiple clinical studies have reported dysregulated...

Allergology International

14h

Is asthma a protective factor for dengue fever? <em>In vitro</em> experiment and nationwide population-based cohort analysis

Publication date: Available online 24 June 2019Source: Allergology InternationalAuthor(s): Hong-Ren Yu, Jui-Hsiu Tsai, Chun-Hung Richard Lin, Jiu-Yao Wang, Yen-Hsia Wen, Shihn-Sheng Wu, Yuan Hou, Ing-Kit Lee, Hung-Pin Tu, Yi-Chen LeeAbstractBackgroundDengue fever (DF) is the most rapidly spreading mosquito-borne viral disease. Practical vaccines or specific therapeutics are still expected. Environmental factors and genetic factors affect the susceptibility of Dengue virus (DV) infection. Asthma is...

Allergology International

14h