Publication date: Available online 26 June 2019Source: Advanced Drug Delivery ReviewsAuthor(s): Yi Lu, Yongjiu Lv, Tonglei LiAbstractNanocrystals show promise to deliver poorly water-soluble drugs to yield systemic exposure. However, our knowledge regarding the in vivo fate of nanocrystals is in its infancy, as nanocrystallization is simply viewed as an approach to enhance the dissolution of drug crystals. The dying crystal phenomenon inspired the development of hybrid nanocrystals by physically...
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