Conditions: PTEN Gene Mutation; PTEN Hamartoma Tumor Syndrome; PTEN Hamartoma Syndrome; Cowden Syndrome; Bannayan Syndrome; Bannayan Zonana Syndrome; PolyposisIntervention: Drug: SirolimusSponsors: Ohio State University; PTEN ResearchRecruiting
Thu Sep 19, 2019 15:19
Related ArticlesGlutamine synthetase facilitates cancer cells to recover from irradiation-induced G2/M arrest. Cancer Biol Ther. 2019 Sep 17;:1-9 Authors: Peng Y, Fu S, Hu W, Qiu Y, Zhang L, Tan R, Sun LQ Abstract Resistance to radiation of cancer cells can be either intrinsic or acquired, leading to treatment failure. In response to DNA damage caused by IR, cancer cells are arrested in cell cycle showing limited proliferation and increased apoptosis....
Thu Sep 19, 2019 15:21
Related ArticlesCombination treatment in metastatic castration-resistant prostate cancer: can we safely boost efficacy by adding radium-223? Cancer Biol Ther. 2019 Sep 18;:1-3 Authors: Knechel MA, Schmidt KT, Figg WD Abstract ERA 223, a phase III, international, multicenter, double-blind study published in Lancet Oncology, was the first randomized controlled trial to investigate combined radium-223 (Ra-223) and abiraterone acetate plus prednisone or...
Thu Sep 19, 2019 15:21
82 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: upper respiratory tract infection These pubmed results were generated on 2019/09/19PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Thu Sep 19, 2019 13:31
82 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: upper respiratory tract infection These pubmed results were generated on 2019/09/19PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Thu Sep 19, 2019 15:31
199 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: ALCOHOL These pubmed results were generated on 2019/09/19PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Thu Sep 19, 2019 13:29
199 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: ALCOHOL These pubmed results were generated on 2019/09/19PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Thu Sep 19, 2019 15:34
Publication date: Available online 18 September 2019Source: Journal of the American College of SurgeonsAuthor(s): Anthony D. Yang, Christopher M. Quinn, D Brock Hewitt, Jeanette W. Chung, Teresa R. Zembower, Andrew Jones, Jo Buyske, David B. Hoyt, Thomas J. Nasca, Karl Y. BilimoriaAbstractBackgroundNeedlestick injuries pose significant health hazards; however, the nationwide frequency of needlesticks and reporting practices among surgical residents is unknown. The objectives of this study were to:...
Thu Sep 19, 2019 15:37
Related ArticlesComparison of UVB effects on growth and induction of UVB screening compounds in isolates of metaphytic algae from temperate zone streams and ponds. J Phycol. 2018 12;54(6):818-828 Authors: O'Neal SW, Hoover AM Abstract Filaments in the surface layers of metaphytic mats are exposed to high photon flux densities of PAR and UVBR. We investigated the effect of UVBR exposure on growth of eight isolates of common metaphytic algae (Cladophora,...
Thu Sep 19, 2019 15:40
Related ArticlesOptimization of Oxygen Dynamics, UV-A Delivery, and Drug Formulation for Accelerated Epi-On Corneal Crosslinking. Curr Eye Res. 2019 Sep 18;: Authors: Hill J, Liu C, Deardorff P, Tavakol B, Eddington W, Thompson V, Gore D, Raizman M, Adler DC Abstract Purpose: Corneal collagen crosslinking (CXL) through an intact epithelium (epi-on) at high irradiance could potentially improve patient comfort, visual recovery, and clinical workflow compared...
Thu Sep 19, 2019 15:40
Related ArticlesBiochemical and biological validations of a faecal glucocorticoid metabolite assay in mandrills (Mandrillus sphinx). Conserv Physiol. 2019;7(1):coz032 Authors: Lavin SR, Woodruff MC, Atencia R, Cox D, Woodruff GT, Setchell JM, Wheaton CJ Abstract Stress is a major factor in determining success when releasing endangered species into the wild but is often overlooked. Mandrills (Mandrills sphinx) are vulnerable to extinction due to habitat...
Thu Sep 19, 2019 15:45
Related ArticlesPerformance in a variable world: using Jensen's inequality to scale up from individuals to populations. Conserv Physiol. 2019;7(1):coz053 Authors: Denny M Abstract Body temperature affects plants' and animals' performance, but these effects are complicated by thermal variation through time within an individual and variation through space among individuals in a population. This review and synthesis describes how the effects of thermal...
Thu Sep 19, 2019 15:45
Related ArticlesEffects of traffic noise exposure on corticosterone, glutathione and tonic immobility in chicks of a precocial bird. Conserv Physiol. 2019;7(1):coz061 Authors: Flores R, Penna M, Wingfield JC, Cuevas E, Vásquez RA, Quirici V Abstract Repeated exposure to traffic noise may be perceived as a succession of stressors, and therefore, noisy urban environments could lead to a state of chronic stress. In developing animals, glucocorticoids can...
Thu Sep 19, 2019 15:45
Related ArticlesRevisit Rates for Pediatric Tonsillectomy: An Analysis of Admit and Discharge Times. Ann Otol Rhinol Laryngol. 2019 Sep 16;:3489419875758 Authors: Gilani S, Bhattacharyya N Abstract OBJECTIVE: To determine the association between intraday timing of outpatient pediatric tonsillectomy and revisit outcomes and complications. STUDY DESIGN: Cross-sectional analysis of New York databases. SETTING: Ambulatory surgery, emergency...
Thu Sep 19, 2019 15:49
Related ArticlesAssessment of Tracheostomy and Laryngectomy Knowledge among Non-Otolaryngology Physicians. Ann Otol Rhinol Laryngol. 2019 Sep 16;:3489419877198 Authors: Hsieh TY, Timbang L, Kuhn M, Brodie H, Squires L Abstract OBJECTIVE: Identify knowledge deficits about alternate airways (AAs) (tracheostomy and laryngectomy) among physicians across multiple specialties a tertiary institution and to assess the impact of an educational lecture on improving...
Thu Sep 19, 2019 15:49
Publication date: Available online 18 September 2019Source: Annals of Anatomy - Anatomischer AnzeigerAuthor(s): Seda Sertel Meyvaci, Belgin Bamaç, Bülent Duran, Tuncay Çolak, Kaya MemişoğluAbstractThe purpose of this study is to determine whether there are differences in proximal femur parameters of women subjected to menopause surgically or naturally. In this study, 10 parameters belonging to proximal femur of a total of 60 women cases of whom 30 had a mean age of 55.53 ± 4.57 years; body mass index,...
Thu Sep 19, 2019 15:51
Related Articles"The Prevalence of Hepatitis C Virus Among Blood Donors Attending Samarra's General Hospital ". Infect Disord Drug Targets. 2019 Sep 15;: Authors: Al-Mahmood A, Al-Jubori A Abstract AIM: To measure the prevalence of hepatitis C virus (HCV) among blood donors attending Samarra'a General Hospital. PATIENTS AND METHODS: A questionnaire was developed in line with the study objectives. It was administered to blood donors visiting...
Thu Sep 19, 2019 15:53
Publication date: Available online 18 September 2019Source: Allergology InternationalAuthor(s): Hisako Okuhira, Yumi Nakatani, Fukumi Furukawa, Nobuo Kanazawa
Thu Sep 19, 2019 15:56
5047 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2019/09/19PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Thu Sep 19, 2019 14:03
5047 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2019/09/19PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Thu Sep 19, 2019 15:58
60 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human homeostasis These pubmed results were generated on 2019/09/19PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Thu Sep 19, 2019 13:59
60 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human homeostasis These pubmed results were generated on 2019/09/19PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Thu Sep 19, 2019 15:59
Related ArticlesYoung-onset dementia: scoping review of key pointers to diagnostic accuracy. BJPsych Open. 2019 Jun 04;5(3):e48 Authors: O'Malley M, Parkes J, Stamou V, LaFontaine J, Oyebode J, Carter J Abstract BACKGROUND: Routine psychiatric assessments tailored to older patients are often insufficient to identify the complexity of presentation in younger patients with dementia. Significant overlap between psychiatric disorders and neurodegenerative...
Thu Sep 19, 2019 16:02
63 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "Proc Natl Acad Sci U S A"[jour] These pubmed results were generated on 2019/09/19PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Thu Sep 19, 2019 14:02
63 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "Proc Natl Acad Sci U S A"[jour] These pubmed results were generated on 2019/09/19PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Thu Sep 19, 2019 16:02
Publication date: Available online 18 September 2019Source: European Journal of Vascular and Endovascular SurgeryAuthor(s): Anders Wanhainen, Kevin Mani
Thu Sep 19, 2019 16:08
Background. Diabetic patients are more susceptible to urinary tract infection compared to nondiabetic patients, Escherichia coli being the most common uropathogen causing UTI. Unreasonable and incorrect antibiotic prescription for UTI in these patients may induce the development of antibiotic-resistant urinary pathogens resulting in delayed recovery and longer hospitalization. In addition to these, biofilm forming capacity of the pathogen may worsen the problem. The main aim of this cross-sectional...
Thu Sep 19, 2019 11:05
Autosomal dominant polycystic kidney disease (ADPKD) is associated with a number of cellular defects such as hyperproliferation, apoptosis, and dedifferentiation. Mutations in polycystin-1 (PC1) account for ∼85% of ADPKD. Here, we showed that wild-type (WT) or mutant PC1 composed of the last five transmembrane (TM) domains and the C-terminus (termed PC1-5TMC) inhibits cell proliferation and protein translation, as well as the downstream effectors of mTOR, consistent with previous reports. Knockdown...
Thu Sep 19, 2019 11:05
Cardiotonic drugs mainly include digitalis, catecholamines, phosphodiesterase inhibitors, and calcium sensitizers, which have been successively discovered and applied in clinical practice. However, there are only a few new drugs available in this field, and the selection is very limited. Digitalis, catecholamines, and phosphodiesterase inhibitors increase myocardial contractility by increasing intracellular concentrations of cyclic adenosine monophosphate (cAMP) and Ca2+, and this increase in intracellular...
Thu Sep 19, 2019 16:05
Related ArticlesResveratrol protects BV2 mouse microglial cells against LPS-induced inflammatory injury by altering the miR-146a-5p/TRAF6/NF-κB axis. Immunopharmacol Immunotoxicol. 2019 Sep 18;:1-9 Authors: Ge YT, Zhong AQ, Xu GF, Lu Y Abstract Objective: To investigate the role of miR-146a-5p in the effects of resveratrol (RSV) on inflammatory response in BV2 mouse microglial cells. Materials and methods: BV2 cells were pretreated by RSV and stimulated...
Thu Sep 19, 2019 16:38
Related ArticlesERGIC3 silencing additively enhances the growth inhibition of BFA on lung adenocarcinoma cells. Curr Cancer Drug Targets. 2019 Sep 17;: Authors: Zhao Q, Wu M, Zheng X, Yang L, Zhang Z, Li X, Chen J Abstract BACKGROUND: Brefeldin A (BFA) has been known to induce endoplasmic reticulum stress (ERS) and Golgi body stress in cancer cells. ERGIC3 (endoplasmic reticulum-Golgi intermediate compartment 3) is a type II transmembrane protein located...
Thu Sep 19, 2019 16:46
Background: Magnetic resonance imaging (MRI) has been widely used for visualizing trigeminal nerves in trigeminal neuralgia. Objective: To assess atrophy and diffusion abnormalities of affected trigeminal nerves in trigeminal neuralgia with 7-T MRI. Methods: In this prospective study, 14 patients (mean age 49 years; range 31–64 years) with trigeminal neuralgia underwent 7-T MRI. We measured trigeminal nerve volumes along their course through the pontocerebellar cistern. We also evaluated fractional...
Thu Sep 19, 2019 16:42
Related ArticlesImpact of hypertension on cerebral microvascular structure in CPAP-treated obstructive sleep apnoea patients: a diffusion magnetic resonance imaging study. Neuroradiology. 2019 Sep 16;: Authors: Thiel S, Gaisl T, Lettau F, Boss A, Winklhofer S, Kohler M, Rossi C Abstract PURPOSE: Obstructive sleep apnoea (OSA) is a highly prevalent sleep-related breathing disorder associated with hypertension, impaired peripheral vascular function and...
Thu Sep 19, 2019 16:50
Related ArticlesComparison of Positive Screening for Obstructive Sleep Apnea in Patients With and Without Cleft Lip and Palate. Cleft Palate Craniofac J. 2019 Sep 17;:1055665619875321 Authors: Gorucu-Coskuner H, Saglam-Aydinatay B, Aksu M, Ozgur FF, Taner T Abstract OBJECTIVE: To compare the prevalence of increased risk of obstructive sleep apnea (OSA) in children with and without cleft lip and/or palate using a previously validated questionnaire and...
Thu Sep 19, 2019 16:50
The United Nations’ International Year of Indigenous Languages is likely to reproduce the colonial logics that underlie dominant narratives of language disappearance and loss. It doesn’t have to be that way. Indigenous Languages matter for development, peacebuilding, and reconciliation. Languages play a crucial role in the daily lives of people, not only as a tool for communication, education, social integration, and development, but also as a repository for each person’s unique identity, cultural...
Thu Sep 19, 2019 16:25
A documentary film shows the challenges faced by Soli children as they learn in a language that is not their own. But does the future have to be in English? “What if the children learned in Soli ? You mean only in Soli? …Without learning through these other languages? Could it happen? Is it possible? We would love that, but can it be?” This is how Stanford, an elder in the Soli speaking village of Lwimba, Zambia, responded to the idea that his grandchildren could be taught in their mother tongue,...
Thu Sep 19, 2019 16:26
The “Going Native” cartoon for this issue of Anthropology News was an exercise in celebration of the International Year of Indigenous Languages, personal discovery, and reverse linguistic imperialism. It is also an opportunity to highlight the discoveries that come from the collaborative aspect of much of my work in indigenous language vitality. I learned Maliseet as my first language but the American school system offered neither support for Maliseet language instruction nor accommodation. By...
Thu Sep 19, 2019 16:27
What a froggy mystery in Papua New Guinea can teach us about the pleasure and power of language diversity. Polopuak—frog. Since 2010, I have been working with Kala speakers in six coastal villages in the Morobe province of Papua New Guinea to document and revitalize their language. In 2010, I’d learned this word, polopuak, as the word for frog in the most northerly of the four Kala dialects, spoken in Manindala village. This struck me as unusual because the four dialects of Kala transition between...
Thu Sep 19, 2019 16:28
In Yakutsk, hip hop can be poetic, nostalgic, and even subversive. What can this inventive genre say about language relocalization and maintenance? A crowd gathers at Muus Khaia (Ice Mountain), a popular restaurant and bar in Yakutsk, the capital of the Sakha Republic. Inside, the stage is backed by a banner reading “Sakha Underground Poetry” in graffiti-style English text. A cartoon graphic of a man wearing a parka, holding a boom box, and smoking a pipe accompanies a list of musical and literary...
Thu Sep 19, 2019 16:29
Ecuador’s Indigenous languages are varied and contested. What can poetry and curing chants tell us about the experience of language change and the people working to reclaim them? Ñukanchik shimipi hatun yachaykuna allichishkakanahun. Chaymanta ñukanchik shimita katichinkapa munanchik, ñukanchik wawakunawan katachinakunchikmi (Great knowledge is saved in our language. For that reason we want to make sure our language continues, and it continues with our children). —Willak, a Kichwa healer. Agato,...
Thu Sep 19, 2019 16:30
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