Radiology: Imaging Cancer, Gary D. Luker

Original Research

Comparative Benefit-to–Radiation Risk Ratio of Molecular Breast Imaging, Two-Dimensional Full-Field Digital Mammography with and without Tomosynthesis, and Synthetic Mammography with Tomosynthesis   Benefit-to-risk ratios with molecular breast imaging are within the lower range of corresponding mammography ratios when accounting for variation in mammographic technique, compressed breast thickness, and age.     Matthew Brown, Matthew F. Covington

Commentary: Let's Get Real about Molecular Breast Imaging and Radiation Risk Carrie B. Hruska

Abbreviated Gadoxetic Acid–enhanced MRI with Second-Shot Arterial Phase Imaging for Liver Metastasis Evaluation   Compared with a full original MRI protocol, an abbreviated gadoxetic acid–enhanced MRI protocol including second-shot arterial phase imaging showed faster image acquisition without compromising diagnostic performance, demonstrated fewer motion artifacts, and preserved visual vascularity (with assistance from the subtraction image) for liver metastasis evaluation.     Jeong Woo Kim, Chang Hee Lee... Kyeong Ah Kim

A Simulation Paradigm for Evaluation of Subtle Liver Lesions at Pediatric CT: Performance and Confidence   A simulation paradigm and user interface for dose reduction research allowed assessment of performance, confidence, and other behavioral metrics that should be accounted for when clinical CT protocols are created and revised.     Jennifer S. Ngo, Justin B. Solomon... Donald P. Frush

q-Space Imaging Yields a Higher Effect Gradient to Assess Cellularity than Conventional Diffusion-weighted Imaging Methods at 3.0 T: A Pilot Study with Freshly Excised Whole-Breast Tumors   q-Space imaging yields a higher effect gradient to assess cellularity in breast cancer compared with conventional diffusion-weighted imaging methods by using a clinical 3.0-T MRI unit to image whole freshly excised breast tumors.     Nicholas Senn, Yazan Masannat... Jiabao He

Endovascular Ion Exchange Chemofiltration Device Reduces Off-Target Doxorubicin Exposure in a Hepatic Intra-arterial Chemotherapy Model   Image-guided endovascular chemofiltration with ionic endovascular devices placed nonocclusively in the hepatic venous outflow tract and inferior vena cava during hepatic artery doxorubicin infusion reduced off-target blood and tissue concentrations of doxorubicin in a translational model.     Colin Yee, David McCoy... Steven W. Hetts

Research Highlights

Hyperpolarized MRI Enhances Early Detection Treatment-induced Changes in Glycolysis Alyssa C. Cutter, Gary D. Luker

Glutamatergic Receptor NMDA PET Imaging via Specific (R) -11C-Me-NB1 Radiotracers Alex N. Frickenstein

68 Ga FAPI PET/CT: Tracer Uptake in 28 Different Kinds of Cancer Deep K. Hathi, Ella F. Jones

Repurposing PSMA PET to Image CAR T Cell Immunotherapy Gary D. Luker

Combination of Chemoembolization plus Radiofrequency Ablation May Provide Better Survival Outcomes than Monotherapy for HCC Luke R. Wilkins