Analytical Chemistry
- [ASAP] Development of a Physiologically Relevant Online Chemical Assay To Quantify Aerosol Oxidative PotentialAnalytical ChemistryDOI: 10.1021/acs.analchem.9b03282
- [ASAP] Separation and Detection of Trace Fentanyl from Complex Mixtures Using Gradient Elution Moving Boundary ElectrophoresisAnalytical ChemistryDOI: 10.1021/acs.analchem.9b03083
- [ASAP] High Resolution Nanoscale Probing of Bacteriophages in an Inhalable Dry Powder Formulation for Pulmonary InfectionsAnalytical ChemistryDOI: 10.1021/acs.analchem.9b02282
Royal Society of Chemistry (Great Britain) Society for Analytical Chemistry Society of Public Analysts (Great Britain)
- Competitive Adsorption on Gold Nanoparticle for Human Papillomavirus 16 L1 Protein Detection by LDI-MSAnalyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN01612K, PaperLi Zhu, Jing Han, Zhihua Wang, Lihui Yin, Wei Zhang, You Peng, Zongxiu NieThe detection of the HPV L1 protein provides information about the infection status of the virus, enables prediction of the development of cervical disease, reflects the replication status of the...The content of this RSS Feed (c) The Royal Society of Chemistry
- Dual-ligand functionalized carbon nanodots as green fluorescent nanosensors for cellular dual receptor-mediated targeting imagingAnalyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN01530B, PaperFangfang Du, xuewei zhao, Wenjing Lu, Zhonghui Guo, Shaomin Shuang, Chuan DongConjugation of ligands to nanoparticle as drug delivery systems targeting specific cells is a promising approach for delivery of therapeutic agents to tumor cells. Herein, we prepared green-emission fluorescent carbon...The content of this RSS Feed (c) The Royal Society of Chemistry
- Carbon Dots-Based Fluorescent Nanoprobe for Associated Detection of Iron Ion and Determination the Fluctuation of Ascorbic Acid Induced by Hypoxia in Cells and in VivoAnalyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN01694E, PaperYan Huang, Na He, Qi Kang, Dazhong Shen, Xiaoyan Wang, Yunqing Wang, Lingxin ChenMaintain the redox balance of biological system is a key point to keep the healthy physiological environment. Excessive iron ion (Fe3+) can cause apoptosis, tissue damage and death. Fortunately, ascorbic...The content of this RSS Feed (c) The Royal Society of Chemistry
- Discriminative potential of ion mobility spectrometry for the detection of fentanyl and fentanyl analogues relative to confounding environmental interferentsAnalyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN01771B, PaperThomas P Forbes, Jeffrey Lawrence, Jennifer R. Verkouteren, Robert Michael VerkouterenThe opioid crisis and emergence of fentanyl, fentanyl analogues, and other synthetic opioids has highlighted the need for sensitive and robust detection for interdiction at screening points, notably vehicles at...The content of this RSS Feed (c) The Royal Society of Chemistry
- Semi-automatic Instrumentation for the nucleic acid extraction and purification to quantify pathogen on the surfaceAnalyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN00896A, PaperWon-Nyoung Lee, Hyun Jin Yoo, Nguyen Kim Huyen, Changyoon Baek, Junhong MinThe public lavatories may be a cause of the spread of infectious pathogen because it is an enclosed space that normal people and patients can use. Surface analysis for microbial...The content of this RSS Feed (c) The Royal Society of Chemistry
- Potentiometric analysis of sialic acid with flexible carbon cloth based on boronate affinity and molecularly imprinted polymersAnalyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN01600G, PaperYanli Zhou, Huijie Huangfu, Jie Yang, Hui Dong, Lantao Liu, Maotian XuAn electrochemical platform was proposed for highly sensitive and selective analysis of sialic acid based on molecularly imprinted polymers (MIPs), which was electropolymerized with monomer molecules of 3-aminophenylboronic acid (ABA)...The content of this RSS Feed (c) The Royal Society of Chemistry
- A Dual-responsive Colorimetric Probe for Detection of Cu2+ and Ni2+ Species in Real Water Samples and Human SerumAnalyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN01451A, PaperGuoxing Yin, Jingfeng Yao, Sai Hong, Yinuo Zhang, Zhaohua Xiao, Ting Yu, Haitao Li, Peng YinThe monitor of heavy transition metals has increasingly attracted great attention for their pollution in the environment and their unique physiological functions. Chemosensors are useful tools for monitoring heavy transition...The content of this RSS Feed (c) The Royal Society of Chemistry
- Cascaded multiple recycling amplifications for aptamer-based ultrasensitive fluorescent detection of protein biomarkersAnalyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN01674K, PaperYao Qin, Daxiu Li, Ruo Yuan, Yun XiangHighly sensitive detection of molecular biomarkers plays a significant role in diagnosing various types of diseases at the early stages. We demonstrated in this paper an ultrasensitive aptamer-based fluorescent method...The content of this RSS Feed (c) The Royal Society of Chemistry
- A Fluorescent Probe Based on Aggregation-Induced Emission for Hydrogen Sulfide-Specific Assaying in Food and Biological SystemAnalyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN01582E, PaperLingfeng Xu, Ling Ni, Lihe Sun, Fang Zeng, Shuizhu WuA fluorescent probe based on a triphenylamine benzopyridine platform for hydrogen sulfide (H2S) assaying has been designed and synthesized. As a result of H2S-triggered cleavage reaction, the disappearance of quenching...The content of this RSS Feed (c) The Royal Society of Chemistry
- Establishment of an immunofiltration strip for the detection of 17β-estradiol based on the photothermal effect of black phosphorescenceAnalyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN01495K, PaperLixia Lu, Minglu Wang, Dan Zhang, Hongyan ZhangRecently, the photothermal effect of nanomaterials has opened the door for new appealing strategy, which would generate a promising and powerful tool when combined with immunoassay. As a new kind...The content of this RSS Feed (c) The Royal Society of Chemistry
- Miniaturized electrochemical platform with integrated PDMS reservoir for label-free DNA hybridization detection using nanostructured Au electrodesAnalyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN01076A, PaperSuryasnata Tripathy, Jose Joseph, Saketh Pothuneedi, Dhruv Das, Siva Rama Krishna Vanjari, Narayana A. V. S. S. Rao, Shiv Govind SinghWe report the fabrication and characterization of a miniaturized electrochemical platform for label-free detection of DNA hybridization. The proposed platform is fabricated by inculcating microfabrication and electrodeposition techniques. Comprising of
BioMed Research International
- Extracorporeal Life Support: The Next Step in Moderate to Severe ARDS—A Review and Meta-Analysis of the LiteratureDespite the use of lung protective ventilation (LPV) strategies, a severe form of acute respiratory distress syndrome (ARDS) is unfortunately associated with high mortality rates, which sometimes exceed 60%. Recently, major technical improvements have been applied in extracorporeal life support (ECLS) systems, but as these techniques are costly and associated with very serious adverse events, high-quality evidence is needed before these technique
- Cell Chromatography-Based Screening of the Active Components in Buyang Huanwu Decoction Promoting Axonal RegenerationBuyang Huanwu decoction (BHD), a popular formulation prescribed in traditional Chinese medicine (TCM) for the treatment of ischemic stroke, has been reported to have a potential role in promoting axonal regeneration. The purpose of the study was to screen and identify bioactive compounds from BHD using live PC12 cells coupled with high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). Using this approach, we successfully id
- Preliminary Investigation of the Diagnosis of Neonatal Congenital Small Bowel Atresia by UltrasoundPurpose. To assess the diagnostic value of ultrasonography (US) for congenital small bowel atresia (SBA) in neonates and their sonographic characteristics. Methods. A retrospective analysis was performed of 20 neonates who were confirmed with SBA by operation from March 2014 to January 2019. All the neonates have been scanned by US before surgery, and no one underwent barium enema or upper gastrointestinal imaging prior to US. Preoperation ultras
- Elevated Preoperative Serum CA125 Predicts Larger Tumor Diameter in Patients with Hepatocellular Carcinoma and Low AFP LevelsAim. Little is known about the association between cancer antigen 125 (MUC16/CA125) concentrations and tumor diameter of patients with hepatocellular carcinoma (HCC) and low AFP levels. To fill this gap in our knowledge, we conducted a retrospective study of 427 patients with HCC with AFP ≤200 ng/mL who underwent R0 resection at our center. Methods. The associations between CA125 concentrations and patients’ clinicopathological characteristics we
- Vascular Endothelial Growth Factor Is Regulated by the Canonical and Noncanonical Transforming Growth Factor-β Pathway in Synovial Fibroblasts Derived from Osteoarthritis PatientsBackground. Previous studies suggest the presence of an association of vascular endothelial growth factor (VEGF) with osteoarthritis (OA) severity and pain in patients with knee OA. VEGF expression in human synovial fibroblasts (SFs) is induced by transforming growth factor-beta (TGFβ). However, the signaling pathway governing TGFβ-mediated regulation of VEGF in SFs has not been identified. Methods. OA patients who underwent total knee arthroplas
- Comparison of Whole-Body Electromyostimulation versus Recognized Back-Strengthening Exercise Training on Chronic Nonspecific Low Back Pain: A Randomized Controlled StudyBackground. Low back pain (LBP) affects almost everyone at least once in their lifetime. Various meta-analyses show promising effects on pain reduction for conventional exercise. However, the lack of time and, especially for pain patients, a fear of movement (“kinesiophobia”) as well as functional limitations often oppose participation in such activities. In contrast, the advantage of novel training technologies like whole-body electromyostimulat
- Observational Study on the Preparation of the Implant Site with Piezosurgery vs. Drill: Comparison between the Two Methods in terms of Postoperative Pain, Surgical Times, and Operational AdvantagesPurpose. Recent advances show that ultrasonic implant site osteotomy is related to a decreased trauma and a better postoperative healing of the surgical site when compared to traditional drilling techniques. The micrometric bone cutting control and the operative advantages related to the piezoelectric approach are also characterized by a learning curve for the clinician in surgical practice and an increased operative duration of the procedure. Th
- A Study of the Change in Sodium and Potassium Ion Concentrations in Stored Donor Blood and Their Effect on Electrolyte Balance of RecipientsBackground. Preserved blood cells undergo progressive structural and functional changes that may affect their function, integrity, and viability after transfusion. The impact of transfusion of stored blood on potassium, sodium, or acid-base balance in the recipient may be complex, but information on it is inconsistent. This study therefore sought to determine the changes in the potassium and sodium levels in whole blood stored at 4°C for 28 days
- Epithelial Mesenchymal and Endothelial Mesenchymal Transitions in Hepatocellular Carcinoma: A ReviewPurpose. To present a comprehensive review of the literature data, published between 2000 and 2019 on the PubMed and Web of Science databases, in the field of the tumor microenvironment in hepatocellular carcinoma (HCC). All the data were combined with the personal experiences of the authors. Design. From 1002 representative papers, we selected 86 representative publications which included data on epithelial-to-mesenchymal transition (EMT), angio
- Drugs and Clinical Approaches Targeting the Antiapoptotic Protein: A ReviewB-cell lymphoma 2 (Bcl-2) is a regulator protein involved in apoptosis. In the past few decades, this protein has been demonstrated to have high efficacy in cancer therapy, and several approaches targeting Bcl-2 have been tested clinically (e.g., oblimersen, ABT-737, ABT-263, obatoclax mesylate, and AT-101). This review reports potential Bcl-2 inhibitors according to current information on their underlying mechanism and the results of clinical tr
PeerJ Computer Science
- FoxO1 is a critical regulator of hepatocyte lipid deposition in chronic stress miceForkhead box O1 (FoxO1) is involved in lipid metabolisms. However, its role in chronic stress-related nonalcoholic fatty liver disease (NAFLD) is unclear. The scientific premise of our study was based on the finding that FoxO1 expression is increased in the liver of mice after chronic stress. It is important to understand the mechanisms involved in the activation of FoxO1 and how its function affects the liver lipid deposition. We employed a muri
- The host range of Aphis gossypii is dependent on aphid genetic background and feeding experienceBackground A polyphagous insect herbivore has a wide range of host plants. However, it has been found that many polyphagous herbivores commonly exhibit a strong preference for a subset of species in their broad host range, and various host biotypes exist in herbivore populations. Nutrition and secondary metabolites in plants affect herbivore preference and performance, but it is still not clear which factors determine the host ra
- Comparison of injury pattern and clinical outcomes between young adults and elderly patients with alcohol-related injury in South Korea 2011–2016Background Alcohol is an important factor that contributes to emergency department (ED) visits due to injury. However, the role of alcohol in elderly patients visiting ED due to injury has not been clearly defined. This study aims to examine age and alcohol as risk factors of injury severity and clinical outcomes. Methods This study included patients who visited EDs
- Long-term studies reveal major environmental factors driving zooplankton dynamics and periodicities in the Black Sea coastal zooplanktonBackground The development and management of shelf-sea ecosystems require a holistic understanding of the factors that influence the zooplankton structure and ecosystem functions. The Black Sea is an example of such areas influenced by eutrophication, overfishing, climate variability, invasions of the ctenophores Mnemiopsis leidyi followed by Beroe ovata. Thus, there is a set of principal factors which may influence and explain periodicities in
- Cytotoxic activity of IMMUNEPOTENT CRP against non-small cell lung cancer cell linesBackground IMMUNEPOTENT-CRP® (I-CRP) is a bovine dialyzable leukocyte extract containing transfer factor. It is a cost-effective, unspecific active immunotherapy that has been used in patients with non-small cell lung cancer (NSCLC) as an adjuvant to reduce the side-effects of chemotherapy and radiotherapy, and has shown cytotoxic activity in vitro on different cancer cell lines. However, its mechanism of action against lung canc
- Warm seawater temperature promotes substrate colonization by the blue coral, Heliopora coeruleaBackground Heliopora coerulea, the blue coral, is a reef building octocoral that is reported to have a higher optimum temperature for growth compared to most scleractinian corals. This octocoral has been observed to grow over both live and dead scleractinians and to dominate certain reefs in the Indo-Pacific region. The molecular mechanisms underlying the ability of H. coerulea to tolerate warmer seawater temperatures and to effectively compete
- Dinosaur paleohistology: review, trends and new avenues of investigationIn the mid-19th century, the discovery that bone microstructure in fossils could be preserved with fidelity provided a new avenue for understanding the evolution, function, and physiology of long extinct organisms. This resulted in the establishment of paleohistology as a subdiscipline of vertebrate paleontology, which has contributed greatly to our current understanding of dinosaurs as living organisms. Dinosaurs are part of a larger group of re
- An update on anatomy and function of the teleost olfactory systemAbout half of all extant vertebrates are teleost fishes. Although our knowledge about anatomy and function of their olfactory systems still lags behind that of mammals, recent advances in cellular and molecular biology have provided us with a wealth of novel information about the sense of smell in this important animal group. Its paired olfactory organs contain up to five types of olfactory receptor neurons expressing OR, TAAR, VR1- and VR2-class
Radiation Molecular Biology.
- The Prevalence and Determinants of Return to Work in Nasopharyngeal Carcinoma SurvivorsPublication date: Available online 27 September 2019Source: International Journal of Radiation Oncology*Biology*PhysicsAuthor(s): Nathaniel So, Lachlan J. McDowell, Lin Lu, Wei Xu, Kathy Rock, John Waldron, Lori J. Bernstein, Hon Biu Chan, Shao Hui Huang, Meredith Giuliani, Andrew Hope, Brian O’Sullivan, Scott V. Bratman, John Cho, John Kim, Raymond Jang, Andrew Bayley, Jolie RingashAbstractPurposeTo assess the employment status in working-age na
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