• pubmed: epilepsy treatment
• Pharmacoresistance - Epidemiology, Mechanisms, And Impact On Epilepsy Treatment.

  Pharmacoresistance - Epidemiology, Mechanisms, And Impact On Epilepsy Treatment. Neuropharmacology. 2019 Sep 24;:107790 Authors: Janmohamed M, Brodie MJ, Kwan P Abstract Understanding the natural history of and factors associated with pharmacoresistant epilepsy provides the foundation for formulating mechanistic hypotheses that can be evaluated to drive the development of novel treatments. This artic

  pubmed: epilepsy treatment

  Sat Sep 28, 2019 13:12
• Levetiracetam treatment ameliorates LRRK2 pathological mutant phenotype.

  Levetiracetam treatment ameliorates LRRK2 pathological mutant phenotype. J Cell Mol Med. 2019 Sep 27;: Authors: Rassu M, Biosa A, Galioto M, Fais M, Sini P, Greggio E, Piccoli G, Crosio C, Iaccarino C Abstract Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common genetic cause of Parkinson's disease (PD). The LRRK2 physiological and pathological function is still debated. However, dif

  pubmed: epilepsy treatment

  Sat Sep 28, 2019 13:12
• Forced Physical Training Increases Neuronal Proliferation and Maturation with Their Integration into Normal Circuits in Pilocarpine Induced Status Epilepticus Mice.

  Forced Physical Training Increases Neuronal Proliferation and Maturation with Their Integration into Normal Circuits in Pilocarpine Induced Status Epilepticus Mice. Neurochem Res. 2019 Sep 27;: Authors: Iqbal M, Xiao XL, Zafar S, Yang PB, Si KW, Han H, Liu JX, Liu Y Abstract Increased number of newly-born neurons produced at latent stage after status epilepticus (SE) contribute to aberrant rewiring o

  pubmed: epilepsy treatment

  Sat Sep 28, 2019 13:12
• Deep Brain Stimulation for Epilepsy: Biomarkers for Optimization.

  Related ArticlesDeep Brain Stimulation for Epilepsy: Biomarkers for Optimization. Curr Treat Options Neurol. 2019 Sep 26;21(10):47 Authors: Dell KL, Cook MJ, Maturana MI Abstract PURPOSE OF REVIEW: Two large-scale controlled clinical trials have provided Class I evidence for the benefit of deep brain stimulation (DBS) as a therapy for refractory epilepsy. However, the efficacy has been variable, with

  pubmed: epilepsy treatment

  Sat Sep 28, 2019 13:12
• The first-line antiepileptic drug carbamazepine: Reaction with biologically relevant free radicals.

  Related ArticlesThe first-line antiepileptic drug carbamazepine: Reaction with biologically relevant free radicals. Free Radic Biol Med. 2018 12;129:559-568 Authors: Martins IL, Nunes J, Charneira C, Morello J, Pereira SA, Telo JP, Marques MM, Antunes AMM Abstract Carbamazepine (CBZ) is one of the most widely used antiepileptic drugs by both adults and children. Despite its widespread use, CBZ is ass

  pubmed: epilepsy treatment

  Sat Sep 28, 2019 13:12
• Genetics, genomics, and genotype-phenotype correlations of TSC: Insights for clinical practice.

  Related ArticlesGenetics, genomics, and genotype-phenotype correlations of TSC: Insights for clinical practice. Am J Med Genet C Semin Med Genet. 2018 09;178(3):281-290 Authors: Peron A, Au KS, Northrup H Abstract Tuberous Sclerosis Complex (TSC) is a multisystem autosomal dominant condition caused by inactivating pathogenic variants in either the TSC1 or the TSC2 gene, leading to hyperactivation of

  pubmed: epilepsy treatment

  Sat Sep 28, 2019 13:12
• Current concepts on epilepsy management in tuberous sclerosis complex.

  Related ArticlesCurrent concepts on epilepsy management in tuberous sclerosis complex. Am J Med Genet C Semin Med Genet. 2018 09;178(3):299-308 Authors: Canevini MP, Kotulska-Jozwiak K, Curatolo P, La Briola F, Peron A, Słowińska M, Strzelecka J, Vignoli A, Jóźwiak S Abstract Tuberous sclerosis complex (TSC) is an autosomal dominant neurocutaneous disease affecting approximately 1 in 6,000 people, an

  pubmed: epilepsy treatment

  Sat Sep 28, 2019 13:12
• Healthcare transition from childhood to adulthood in Tuberous Sclerosis Complex.

  Related ArticlesHealthcare transition from childhood to adulthood in Tuberous Sclerosis Complex. Am J Med Genet C Semin Med Genet. 2018 09;178(3):355-364 Authors: Peron A, Canevini MP, Ghelma F, Di Marco F, Vignoli A Abstract Healthcare transition from childhood to adulthood is required to ensure continuity of care of an increasing number of individuals with chronic conditions surviving into adulthoo

  pubmed: epilepsy treatment

  Sat Sep 28, 2019 13:12
• Complete heart block by lacosamide.

  Related ArticlesComplete heart block by lacosamide. Med Clin (Barc). 2018 08 22;151(4):166-167 Authors: Recena Pérez P, Leizaola Irigoyen O, Antuña Braña MT PMID: 29496248 [PubMed - indexed for MEDLINE]

  pubmed: epilepsy treatment

  Sat Sep 28, 2019 13:12
• Normocytic Normochromic Anaemia and Asymptomatic Neutropenia in a 40-Day-Old Infant Breastfed by an Epileptic Mother Treated With Lamotrigine: Infant's Adverse Drug Reaction.

  Related ArticlesNormocytic Normochromic Anaemia and Asymptomatic Neutropenia in a 40-Day-Old Infant Breastfed by an Epileptic Mother Treated With Lamotrigine: Infant's Adverse Drug Reaction. J Paediatr Child Health. 2018 01;54(1):104-105 Authors: Bedussi F, Relli V, Faraoni L, Eleftheriou G, Giampreti A, Gallo M, Lorenzi F, Sangiovanni A, Chiara F, Maccioni R, Pilloni PP, Falchi G, Scanu M, Butera R, Bacis G

  pubmed: epilepsy treatment

  Sat Sep 28, 2019 13:12
• Cannabidiol for drug-resistant seizures in the Dravet syndrome.

  Related ArticlesCannabidiol for drug-resistant seizures in the Dravet syndrome. J Paediatr Child Health. 2018 01;54(1):101-102 Authors: Mellis C PMID: 29314377 [PubMed - indexed for MEDLINE]

  pubmed: epilepsy treatment

  Sat Sep 28, 2019 13:12
• Targeted nanoparticles for precise cancer therapy.

  Related ArticlesTargeted nanoparticles for precise cancer therapy. Sci China Life Sci. 2019 Sep 16;: Authors: Wang J, Wang Y, Wang R, Zhang S, Liu X, Liang XJ PMID: 31555962 [PubMed - as supplied by publisher]

  pubmed: epilepsy treatment

  Fri Sep 27, 2019 03:23
• Anatomic and Thermometric Analysis of Cranial Nerve Palsy after Laser Amygdalohippocampotomy for Mesial Temporal Lobe Epilepsy.

  Related ArticlesAnatomic and Thermometric Analysis of Cranial Nerve Palsy after Laser Amygdalohippocampotomy for Mesial Temporal Lobe Epilepsy. Oper Neurosurg (Hagerstown). 2019 Sep 25;: Authors: Huang Y, Leung SA, Parker JJ, Ho AL, Wintermark M, Patel SH, Pauly KB, Kakusa BW, Beres SJ, Henderson JM, Grant GA, Halpern CH Abstract BACKGROUND: Laser interstitial thermal therapy (LITT) is a minimally in

  pubmed: epilepsy treatment

  Fri Sep 27, 2019 03:23
• Brain arteriovenous malformation with transdural blood supply: Current status.

  Related ArticlesBrain arteriovenous malformation with transdural blood supply: Current status. Exp Ther Med. 2019 Oct;18(4):2363-2368 Authors: Piao J, Ji T, Guo Y, Xu K, Yu J Abstract Arterial blood supply to a brain arteriovenous malformation (BAVM) is mainly derived from the internal carotid artery (ICA) and vertebral basilar artery (VBA) system. However, in certain cases, arteries supplying the me

  pubmed: epilepsy treatment

  Fri Sep 27, 2019 03:23
• Transient Epileptic Amnesia: A Treatable Cause of Spells Associated With Persistent Cognitive Symptoms.

  Related ArticlesTransient Epileptic Amnesia: A Treatable Cause of Spells Associated With Persistent Cognitive Symptoms. Front Neurol. 2019;10:939 Authors: Ramanan VK, Morris KA, Graff-Radford J, Jones DT, Burkholder DB, Britton JW, Josephs KA, Boeve BF, Savica R Abstract Objective: To characterize the clinical, EEG, and neuroimaging profiles of transient epileptic amnesia (TEA). Methods: We performed

  pubmed: epilepsy treatment

  Fri Sep 27, 2019 03:23
• Cell-Free Expression of Sodium Channel Domains for Pharmacology Studies. Noncanonical Spider Toxin Binding Site in the Second Voltage-Sensing Domain of Human Nav1.4 Channel.

  Related ArticlesCell-Free Expression of Sodium Channel Domains for Pharmacology Studies. Noncanonical Spider Toxin Binding Site in the Second Voltage-Sensing Domain of Human Nav1.4 Channel. Front Pharmacol. 2019;10:953 Authors: Myshkin MY, Männikkö R, Krumkacheva OA, Kulbatskii DS, Chugunov AO, Berkut AA, Paramonov AS, Shulepko MA, Fedin MV, Hanna MG, Kullmann DM, Bagryanskaya EG, Arseniev AS, Kirpichnikov MP, Lyukman

  pubmed: epilepsy treatment

  Fri Sep 27, 2019 03:23
• Behavioural changes in dogs with idiopathic epilepsy.

  Related ArticlesBehavioural changes in dogs with idiopathic epilepsy. Vet Rec. 2019 Sep 25;: Authors: Watson F, Packer RMA, Rusbridge C, Volk HA Abstract BACKGROUND: Breed-specific and broader cohort studies have shown behavioural changes in dogs following the onset of idiopathic epilepsy (IE). METHODS: A cross-sectional, case-control questionnaire study was carried out to strengthen this bo

  pubmed: epilepsy treatment

  Fri Sep 27, 2019 03:23
• Associations between neutering and idiopathic epilepsy in Labrador retrievers and Border collies under primary veterinary care in the UK.

  Related ArticlesAssociations between neutering and idiopathic epilepsy in Labrador retrievers and Border collies under primary veterinary care in the UK. Vet J. 2019 Oct;252:105354 Authors: Van Meervenne S, Volk HA, Verhoeven PS, Van Ham L, O'Neill DG Abstract There are sparse published scientific data on associations between neutering and the severity and survival of dogs with idiopathic epilepsy. T

  pubmed: epilepsy treatment

  Fri Sep 27, 2019 03:23
• Impact on Clinical Decision Making of Next-Generation Sequencing in Pediatric Epilepsy in a Tertiary Epilepsy Referral Center.

  Related ArticlesImpact on Clinical Decision Making of Next-Generation Sequencing in Pediatric Epilepsy in a Tertiary Epilepsy Referral Center. Clin EEG Neurosci. 2019 Sep 25;:1550059419876518 Authors: Hoelz H, Herdl C, Gerstl L, Tacke M, Vill K, von Stuelpnagel C, Rost I, Hoertnagel K, Abicht A, Hollizeck S, Larsen LHG, Borggraefe I Abstract Background. Next-generation sequencing (NGS) describes new

  pubmed: epilepsy treatment

  Fri Sep 27, 2019 03:23
• Providing Surgery for Medically Intractable Epilepsy in Low- and Middle-Income Countries: Shifting the Focus From If to How.

  Related ArticlesProviding Surgery for Medically Intractable Epilepsy in Low- and Middle-Income Countries: Shifting the Focus From If to How. JAMA Neurol. 2018 09 01;75(9):1041-1042 Authors: Mansouri A, Ibrahim GM PMID: 29868801 [PubMed - indexed for MEDLINE]

  pubmed: epilepsy treatment

  Fri Sep 27, 2019 03:23
• Using high-amplitude and focused transcranial alternating current stimulation to entrain physiological tremor.

  Related ArticlesUsing high-amplitude and focused transcranial alternating current stimulation to entrain physiological tremor. Sci Rep. 2018 03 21;8(1):4927 Authors: Khatoun A, Breukers J, Op de Beeck S, Nica IG, Aerts JM, Seynaeve L, Haeck T, Asamoah B, Mc Laughlin M Abstract Transcranial alternating current stimulation (tACS) is a noninvasive neuromodulation method that can entrain physiological tr

  pubmed: epilepsy treatment

  Fri Sep 27, 2019 03:23
• Ambiguous Genitalia Associated with an Extremely Rare Syndrome: A Case Report of XLAG Syndrome and Review of the Literature.

  Related ArticlesAmbiguous Genitalia Associated with an Extremely Rare Syndrome: A Case Report of XLAG Syndrome and Review of the Literature. Turk Patoloji Derg. 2019;35(2):162-165 Authors: Gupta B, Ramteke P, Paul VK, Kumar T, DAS P Abstract X-linked lissencephaly, absent corpus callosum, and epilepsy of neonatal onset with ambiguous genitalia comprises the XLAG syndrome and only 15 cases have been r

  pubmed: epilepsy treatment

  Fri Sep 27, 2019 03:23
• GeneReviews®

  Related ArticlesGeneReviews® Book. 1993 Authors: Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Stephens K, Amemiya A Abstract CLINICAL CHARACTERISTICS: BCL11A-related intellectual disability (BCL11A-ID) is characterized by developmental delay / intellectual disability of variable degree, neonatal hypotonia, microcephaly, distinctive but variable facial characteristics, behavior problems, and asymptomatic persi

  pubmed: epilepsy treatment

  Fri Sep 27, 2019 04:41
• pubmed: her2-positive breast...
• Evaluating the preoperative breast cancer characteristics affecting the accuracy of axillary ultrasound staging.

  Evaluating the preoperative breast cancer characteristics affecting the accuracy of axillary ultrasound staging. Breast J. 2019 Sep 27;: Authors: Upadhyaya VS, Lim GH, Chan EYK, Fook-Chong SMC, Leong LCH Abstract We evaluate the preoperative breast cancer (BC) characteristics that affect the diagnostic accuracy of axillary ultrasound (US) and determine the reliability of US in the different subgroups

  pubmed: her2-positive breast...

  Sun Sep 29, 2019 03:28
• A novel 3'-tRNAGlu-derived fragment acts as a tumor-suppressor in breast cancer by targeting nucleolin.

  Related ArticlesA novel 3'-tRNAGlu-derived fragment acts as a tumor-suppressor in breast cancer by targeting nucleolin. FASEB J. 2019 Sep 27;:fj201900382RR Authors: Falconi M, Giangrossi M, Zabaleta ME, Wang J, Gambini V, Tilio M, Bencardino D, Occhipinti S, Belletti B, Laudadio E, Galeazzi R, Marchini C, Amici A Abstract tRNA-derived fragments (tRFs) have been defined as a novel class of small nonco

  pubmed: her2-positive breast...

  Sun Sep 29, 2019 03:28
• Comparative anti-proliferative effects of potential HER2 inhibitors on a panel of breast cancer cell lines.

  Related ArticlesComparative anti-proliferative effects of potential HER2 inhibitors on a panel of breast cancer cell lines. Breast Cancer. 2019 Sep 26;: Authors: Zalloum H, AbuThiab T, Hameduh T, AlBayyari S, Zalloum W, Abu-Irmaileh B, Mubarak MS, Zihlif M Abstract BACKGROUND: Breast cancer is one of the most lethal types of cancer in women worldwide. The human epidermal growth factor receptor 2 (HER

  pubmed: her2-positive breast...

  Sat Sep 28, 2019 13:08
• Pre- and Postoperative Neratinib for HER2-Positive Breast Cancer Brain Metastases: Translational Breast Cancer Research Consortium 022.

  Related ArticlesPre- and Postoperative Neratinib for HER2-Positive Breast Cancer Brain Metastases: Translational Breast Cancer Research Consortium 022. Clin Breast Cancer. 2019 Aug 22;: Authors: Freedman RA, Gelman RS, Agar NYR, Santagata S, Randall EC, Gimenez-Cassina Lopez B, Connolly RM, Dunn IF, Van Poznak CH, Anders CK, Melisko ME, Silvestri K, Cotter CM, Componeschi KP, Marte JM, Moy B, Blackwell KL, Puhalla SL,

  pubmed: her2-positive breast...

  Sat Sep 28, 2019 13:08
• Cost-Effectiveness Analysis of Adjuvant Neratinib Following Trastuzumab in Early-Stage HER2-Positive Breast Cancer.

  Related ArticlesCost-Effectiveness Analysis of Adjuvant Neratinib Following Trastuzumab in Early-Stage HER2-Positive Breast Cancer. J Manag Care Spec Pharm. 2019 Oct;25(10):1133-1139 Authors: Schwartz NRM, Flanagan MR, Babigumira JB, Steuten LM, Roth JA Abstract BACKGROUND: Disease-free survival (DFS) in early-stage human epidermal growth factor receptor 2 (HER2)-positive breast cancer is significant

  pubmed: her2-positive breast...

  Fri Sep 27, 2019 04:14
• Outcome of Omani Women with Breast Cancer-associated Brain Metastases Experience from a University Hospital.

  Related ArticlesOutcome of Omani Women with Breast Cancer-associated Brain Metastases Experience from a University Hospital. Oman Med J. 2019 Sep;34(5):412-419 Authors: Zahid KF, Kumar S, Al-Bimani K, Ahmed T, Al-Ajmi A, Burney IA, Al-Moundhri M Abstract Objectives: Breast cancer (BC) is the leading cancer among women. Almost 20% of patients develop brain metastases (BM) and die shortly afterward. Th

  pubmed: her2-positive breast...

  Fri Sep 27, 2019 04:14
• pubmed: basal ganglia stroke...
• Endovascular Therapy for Concurrent Cardio-Cerebral Infarction in a Patient With Trousseau Syndrome.

  Related ArticlesEndovascular Therapy for Concurrent Cardio-Cerebral Infarction in a Patient With Trousseau Syndrome. Front Neurol. 2019;10:965 Authors: Sakuta K, Mukai T, Fujii A, Makita K, Yaguchi H Abstract Only a few patients have been reported to undergo endovascular therapy for Trousseau syndrome. This is the first report of a patient with Trousseau syndrome who developed synchronous cardiocereb

  pubmed: basal ganglia stroke...

  Fri Sep 27, 2019 03:39