Publication date: Available online 16 September 2019Source: Academic RadiologyAuthor(s): Morikatsu Yoshida, Takeshi Nakaura, Takada Sentaro, Shota Tanoue, Hatsuki Inada, Daisuke Utsunomiya, Naritsugu Sakaino, Kazunori Harada, Yasuyuki YamashitaRationale and ObjectivesTo compare the objective and subjective image qualities between single-energy computed tomography (CT) at 70 kVp and virtual monoenergetic imaging (VMI) of dual-source dual-energy CT for CT angiography with 180 mgI/kg.Materials and MethodsTotal...
Publication date: Available online 16 September 2019Source: Academic RadiologyAuthor(s): Halit Nahit Şendur, Mahi Nur Cerit, Serap Gültekin, Emetullah Cindil, Pınar KılıçObjectivesTo compare mass size measurements between synthesized mammography (SM) and full-field digital mammography (FFDM), and to assess interobserver agreement for those measurements.Materials and MethodsOne hundred and forty-three patients who underwent FFDM and digital breast tomosynthesis acquisitions during the same compression...
Publication date: Available online 16 September 2019Source: Academic RadiologyAuthor(s): Mohammad Hadi Bagheri, Holger Roth, William Kovacs, Jianhua Yao, Faraz Farhadi, Xiaobai Li, Ronald M. SummersPurposeAccurate pancreas segmentation has application in surgical planning, assessment of diabetes, and detection and analysis of pancreatic tumors. Factors that affect pancreas segmentation accuracy have not been previously reported. The purpose of this study is to identify technical and clinical factors...
Publication date: Available online 17 September 2019Source: Academic RadiologyAuthor(s): Po-Hao ChenNatural language is ubiquitous in the workflow of medical imaging. Radiologists create and consume free text in their daily work, some of which can be amenable to enhancements through automatic processing. Recent advancements in deep learning and “artificial intelligence” have had a significant positive impact on natural language processing (NLP). This article discusses the history of how researchers...
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Constitutive activation of FGFR1, as a result of diverse chromosome translocations, is the hallmark of stem cell leukemia/lymphoma syndrome. The BCR‐FGFR1 variant is unique in that the BCR component contributes a serine‐threonine kinase (STK) to the N‐terminal end of the chimeric FGFR1 kinase. We have deleted the STK domain and mutated the critical Y177 residue and demonstrate that the transforming activity of these mutated genes is reduced compared with the BCR‐FGFR1 parental kinase. In addition,...
Chitinase‐like proteins (CLP) are chitin‐binding proteins that lack chitin hydrolyzing activity, but possess cytokine‐like and growth factor‐like properties, and play crucial role in intercellular crosstalk. Both human and mice express two members of CLP family: YKL‐40 and stabilin‐1 interacting chitinase‐like protein (SI‐CLP). Despite numerous reports indicating the role of YKL‐40 in the support of angiogenesis, tumor cell proliferation, invasion and metastasis, the role of its structurally related...
Colorectal cancer (CRC) is a complex disorder for which the majority of the underlying germline predisposition factors remain still unidentified. Here, we combined whole‐exome sequencing (WES) and linkage analysis in families with multiple relatives affected by CRC to identify candidate genes harboring rare variants with potential high‐penetrance effects. Forty‐seven affected subjects from 18 extended CRC families underwent WES. Genome‐wide linkage analysis was performed under linear and exponential...
The current study aimed to investigate the relationship between red and white meat subtypes, processed meat (divided into traditional “Khlii, Kaddid” and industrially processed meat) and colorectal cancer (CRC) risk, considering CRC sub‐sites, in Moroccan adults. A case–control study was conducted including 2,906 matched case–control pairs recruited from the five largest university hospitals in Morocco. Dietary data were collected through a validated Food Frequency Questionnaire (FFQ). Multivariable...
Previously, our lab discovered the protein Nischarin and uncovered its role in regulating cell migration and invasion via its interactions with several proteins. We subsequently described a role for Nischarin in breast cancer, in which it is frequently underexpressed. To characterize Nischarin's role in breast tumorigenesis and mammary gland development more completely, we deleted a critical region of the Nisch gene (exons 7–10) from the mouse genome and observed the effects. Mammary glands in mutant...
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116 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: ALCOHOL These pubmed results were generated on 2019/09/17PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
116 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: ALCOHOL These pubmed results were generated on 2019/09/17PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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18 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "J Drugs Dermatol"[jour] These pubmed results were generated on 2019/09/17PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
18 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "J Drugs Dermatol"[jour] These pubmed results were generated on 2019/09/17PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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4139 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2019/09/17PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
4139 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2019/09/17PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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74 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human homeostasis These pubmed results were generated on 2019/09/17PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
74 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human homeostasis These pubmed results were generated on 2019/09/17PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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32 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "Ann Plast Surg"[jour] These pubmed results were generated on 2019/09/17PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
32 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "Ann Plast Surg"[jour] These pubmed results were generated on 2019/09/17PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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103 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: upper respiratory tract infection These pubmed results were generated on 2019/09/17PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
103 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: upper respiratory tract infection These pubmed results were generated on 2019/09/17PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Background and Aim. Serum Golgi protein 73 (GP73) is a promising alternative biomarker of chronic liver diseases, but most data are from patients with HBV infection rather than HCV. Materials and Methods. Two independent cohorts of chronic hepatitis C (CHC) patients from the 5th Medical Centre of the Chinese PLA General Hospital () and Beijing Youan Hospital () with different histories of HCV infection were enrolled. The correlations between serum GP73 and other biochemical indices, as well as its...
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Cancers, Vol. 11, Pages 1384: Molecular Mechanisms Underlying Yatein-Induced Cell-Cycle Arrest and Microtubule Destabilization in Human Lung Adenocarcinoma Cells Cancers doi: 10.3390/cancers11091384 Authors: Shang-Tse Ho Chi-Chen Lin Yu-Tang Tung Jyh-Horng Wu Yatein is an antitumor agent isolated from Calocedrus formosana Florin leaves extract. In our previous study, we found that yatein inhibited the growth of human lung adenocarcinoma A549 and CL1-5 cells by inducing intrinsic...
Cancers, Vol. 11, Pages 1383: Encapsulated Carbenoxolone Reduces Lung Metastases Cancers doi: 10.3390/cancers11091383 Authors: Adi Karsch-Bluman Shimrit Avraham Miri Assayag Ouri Schwob Ofra Benny Carbenoxolone is an anti-inflammatory compound and a derivate of a natural substance from the licorice plant. We previously showed that carbenoxolone reduces the metastatic burden in the lungs of mice through its antagonistic effect on high mobility group box 1 (HMGB1). To further...
Cancers, Vol. 11, Pages 1385: XIST-Promoter Demethylation as Tissue Biomarker for Testicular Germ Cell Tumors and Spermatogenesis Quality Cancers doi: 10.3390/cancers11091385 Authors: Lobo Nunes Gillis Barros-Silva Miranda-Gonçalves Berg Cantante Guimarães Henrique Jerónimo Looijenga Background: The event of X chromosome inactivation induced by XIST, which is physiologically observed in females, is retained in testicular germ cell tumors (TGCTs),...
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Publication date: Available online 16 September 2019Source: International Journal of Radiation Oncology*Biology*PhysicsAuthor(s): Camille Hardy-Abeloos, Stanislav Lazarev, Meng Ru, Edward Kim, Aaron Fischman, Erin Moshier, Kenneth Rosenzweig, Michael BucksteinAbstract:Purpose/Objective(s)With increasing use of radiation for hepatocellular carcinoma (HCC) through trans-arterial radioembolization (TARE) and stereotactic body radiation therapy (SBRT), there is concern for increased radiation related...
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Abstract The pathologist Walter Müller is undoubtedly one of the most prominent post-war representatives of his profession. He became full professor and founding dean in Essen, and in 1983 the German Society for Pathology (DGP) awarded him the Rudolf Virchow Medal – the highest distinction of the society – for his merits to the field of pathology. But this glorious career was by no means predetermined. Rather, after the end of the Second World War there were...
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In the publication of this article [1], there are two corrections.
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Publication date: November 2019Source: Biomedicine & Pharmacotherapy, Volume 119Author(s): Zhengna Yin, Yuan Mao, Ningzhi Zhang, Yiping Su, Jin Zhu, Hua Tong, Huilin ZhangAbstractBackgroundOver-expression of Receptor-tyrosine-kinase-like Orphan Receptor 1 (ROR1) in cancer cells has been reported in the context of several tumors (including ovarian cancer) and is associated with poor prognosis. The aim of this study was to construct a fully chimeric anti-ROR1 IgG antibody (ROR1-IgG) and investigate...
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Abdominal hemangiolymphangioma (HLA) in neonates is a rare condition that demands surgical intervention after a complete preoperative diagnostic approach. The differential diagnosis and the establishment of a therapeutic algorithm is a challenge, both for the neonatologists and the pediatric surgeons, because there is no consensus in the management of HLAs in infancy according to the literature. We report a rare case of abdominal HLA in a female newborn that was admitted to our pediatric surgery...
The differential diagnosis of a congenital cutaneous vascular-appearing mass in a newborn is broad and includes both benign and malignant tumors. We report the case of a newborn who presented with an erythematous exophytic skin nodule on the right upper leg. Excision was performed due to ulceration, concern for bleeding, and for diagnosis. Pathology revealed the mass to be an infantile myofibroma. This case highlights the importance of considering a broad differential diagnosis in a newborn with...
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Stem Cells and Development, Ahead of Print.
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Abstract One of the core mechanisms involved in the control of saccade responses to selected target stimuli is the disengagement from the current fixation location, so that the next saccade can be executed. To carry out everyday visual tasks, we make multiple eye movements that can be programmed in parallel. However, the role of disengagement in the parallel programming of saccades has not been examined. It is well established that the need for disengagement slows down saccadic...
Abstract In this paper, we analyze the relationship between head and chest movements and gaze direction in both walking and non-walking conditions. In a different approach from existing studies, we aim to analyze behavior when humans intentionally gaze at a certain target from two perspectives: (1) the relationship between gaze and body movements and (2) the effects of walking on body motion. We performed three experiments: fixed target scenes (Experiment 1), moving target scenes...
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