Publication date: Available online 10 September 2019Source: Archives of Physical Medicine and RehabilitationAuthor(s): Abhishek Jaywant, Joan Toglia, Faith M. Gunning, Michael W. O’DellAbstractObjectiveTo validate subgroups of cognitive impairment on the Montreal Cognitive Assessment (MoCA)—defined as Normal (score of 25-30), Mildly Impaired (score of 20-24), and Moderately Impaired (score less than 19)—by determining whether they differ in rehabilitation gain during inpatient stroke rehabilitation.DesignObservational...
Wed Sep 11, 2019 16:53
Publication date: Available online 10 September 2019Source: Archives of Physical Medicine and RehabilitationAuthor(s): Arun Jayaraman, Megan K. O’Brien, Sangeetha Madhavan, Kiyoshi Oikawa, Yosuke Endo, Shailesh Kantak, James Stinear, T. George Hornby, William Zev RymerAbstractObjectiveTo examine the immediate effects of a hip-assistive wearable robotic exoskeleton on clinical walking performance, walking energetics, gait kinematics, and corticomotor excitability in individuals with stroke.DesignRandomized...
Wed Sep 11, 2019 16:53
Publication date: Available online 10 September 2019Source: Medical Image AnalysisAuthor(s): Rongjun Ge, Guanyu Yang, Yang Chen, Limin Luo, Cheng Feng, Heye Zhang, Shuo LiAbstractAccurate direct estimation of the left ventricle (LV) multitype indices from two-dimensional (2D) echocardiograms of paired apical views, i.e., paired apical four-chamber (A4C) and two-chamber (A2C), is of great significance to clinically evaluate cardiac function. It enables a comprehensive assessment from multiple dimensions...
Wed Sep 11, 2019 16:57
Abstract Good posture means spine is neutral. Posture is dictated by the existing occlusion, especially the relation between the maxillary and mandibular permanent first molars. Overloading the spine due to bad posture is the precursor of many ailments. Obstructive Sleep Apnea Syndrome is one of them. Compromised airway is found to be a major contributory factor in sleep apnea cases. Restoring the dental anatomy to its normal has been found to reduce the load on the spine, improving...
Wed Sep 11, 2019 03:00
Related ArticlesPatterns of recurrence after open partial horizontal laryngectomy types II and III: univariate and logistic regression analysis of risk factors. Acta Otorhinolaryngol Ital. 2019 Aug;39(4):235-243 Authors: Crosetti E, Bertolin A, Molteni G, Bertotto I, Balmativola D, Carraro M, Sprio AE, Berta GN, Presutti L, Rizzotto G, Succo G PMID: 31501615 [PubMed - in process]
Wed Sep 11, 2019 17:00
Related ArticlesTime as a factor during endoscopic assessment of swallowing: relevance in defining the score and severity of swallowing disorders. Acta Otorhinolaryngol Ital. 2019 Aug;39(4):244-249 Authors: Farneti D, Fattori B, Bastiani L PMID: 31501616 [PubMed - in process]
Wed Sep 11, 2019 17:00
Related ArticlesHearing loss in very preterm infants: should we wait or treat? Acta Otorhinolaryngol Ital. 2019 Aug;39(4):257-262 Authors: Frezza S, Catenazzi P, Gallus R, Gallini F, Fioretti M, Anzivino R, Corsello M, Cota F, Vento G, Conti G PMID: 31501617 [PubMed - in process]
Wed Sep 11, 2019 17:00
Related ArticlesHeight intolerance between physiological mechanisms and psychological distress: a review of literature and our experience. Acta Otorhinolaryngol Ital. 2019 Aug;39(4):263-268 Authors: Teggi R, Comacchio F, Fornasari F, Mira E PMID: 31501618 [PubMed - in process]
Wed Sep 11, 2019 17:00
Related Articles3T MRI-based estimation of scalar cochlear implant electrode position. Acta Otorhinolaryngol Ital. 2019 Aug;39(4):269-273 Authors: Tek F, MüLler S, Boga E, Gehl HB, Seitz D, Scholtz LU, Sudhoff H, Todt I PMID: 31501619 [PubMed - in process]
Wed Sep 11, 2019 17:00
Publication date: Available online 10 September 2019Source: Archives of Oral BiologyAuthor(s): Nezahat Arzu Kayar, İlhami Çeli, Nilgün Özlem AlptekinAbstractObjectivePreterm Low-Birth-Weight (PLBW) is frequently associated with periodontal disease. However, the mechanism is still unknown. The present study was performed to examine the possible link between periodontal infections and PLBW in post-partum women utilizing clinical parameters and CD4+ and CD8 + T lymphocytes ratio in gingival granulation...
Wed Sep 11, 2019 17:02
Publication date: November 2019Source: Biomedicine & Pharmacotherapy, Volume 119Author(s): Rong Li, Yan Liu, Tiying Wang, Jiadai Tang, Lin Xie, Zhihong Yao, Kechen Li, Yedan Liao, Ling Zhou, Zhenqin Geng, Zeyong Huang, Zuozhang Yang, Lei HanAbstractThe occurrence of lung cancers is the highest in Xuanwei County, Yunnan province, China, especially among nonsmoking women. Domestic combustion of smoky coal induces serious indoor air pollution and is considered to be the main cause of human lung...
Wed Sep 11, 2019 17:05
Publication date: November 2019Source: Biomedicine & Pharmacotherapy, Volume 119Author(s): Zelin Tian, Jianing Tang, Qian Yang, Xin Li, Jian Zhu, Gaosong WuAbstractBreast cancer ranks first among female malignancies worldwide, and estrogen receptor-positive (ER+) breast cancer is the leading cause of cancer death in women. Abnormal oncogenic signaling has important effects on the development of breast cancer, such as ERα/ ESR1 (estrogen receptor alpha), PTEN (gene of phosphate and tension homology...
Wed Sep 11, 2019 17:05
Publication date: November 2019Source: Biomedicine & Pharmacotherapy, Volume 119Author(s): Jie Fu, Lilei Peng, Tao Tao, Yangmei Chen, Zuoxiao Li, Jinglun LiAbstractNeurodegenerative diseases are chronic and progressive disorders which are not effectively treated through adopting conventional therapies. For this unmet medical need, alternative therapeutic methods including gene-based therapies are emphasized. MicroRNAs (miRNAs) are small non-coding RNAs which can regulate gene expression at the...
Wed Sep 11, 2019 17:05
Publication date: November 2019Source: Biomedicine & Pharmacotherapy, Volume 119Author(s): Qiong-Qiong Xing, Li-Wei Liu, Xia Zhao, Yuan Lu, Ying-Mei Dong, Zhong-Qing LiangAbstractGubenfangxiao decoction (GBFXD) is a traditional Chinese medicine formula derived from Yupingfengsan, an ancient formula widely used to treat respiratory diseases. In recent years, GBFXD has been applied to efficaciously and safely treat asthma. However, the mechanism of GBFXD is still not fully elucidated. The aim of...
Wed Sep 11, 2019 17:05
A novel human anti-BAFF neutralizing monoclonal antibody derived from <em>in vitro</em> immunization
Publication date: November 2019Source: Biomedicine & Pharmacotherapy, Volume 119Author(s): Yue Tong, Shengwei Zhong, Zhenzhen Shan, Wenbing Yao, Hong TianAbstractB-cell activating factor (BAFF) plays a key role in the normal regulation of B cell development and immune response. Its abnormal expression level is accompanied by the occurrence of various autoimmune diseases. Therefore, BAFF is an effective target for the treatment of such diseases. Here, we report a new anti-BAFF monoclonal antibody....
Wed Sep 11, 2019 17:05
Publication date: November 2019Source: Biomedicine & Pharmacotherapy, Volume 119Author(s): Size Li, Yiqun Yu, Zhiping Jin, Yu Dai, Haishu Lin, Zheng Jiao, Guo Ma, Weimin Cai, Bing Han, Xiaoqiang XiangAbstractAtorvastatin and its lactone form metabolite are reported to be associated with statin-induced myopathy (SIM) such as myalgia and life-threatening rhabdomyolysis. Though the statin-induced rhabdomyolysis is not common during statin therapy, its incidence will significantly increase due to...
Wed Sep 11, 2019 17:05
Publication date: November 2019Source: Biomedicine & Pharmacotherapy, Volume 119Author(s): Ge Tang, Fengqi Duan, Weixuan Li, Yiqin Wang, Cheng Zeng, Jia Hu, Hongyu Li, Xuanhong Zhang, Yanming Chen, Hongmei TanAbstractAimsThe present study aimed to investigate the effect of metformin on diabetes-accelerated atherosclerosis and whether Nod-like receptor protein 3 (NLRP3) inflammasome is a target for metformin.Materials and methodsApoE−/− male mice were divided randomly into control, streptozocin-induced...
Wed Sep 11, 2019 17:05
Publication date: November 2019Source: Biomedicine & Pharmacotherapy, Volume 119Author(s): Tao Huang, Yue Fu, Siqi Wang, Man Xu, Xiaolin Yin, Minran Zhou, Xiaoming Wang, Chunyan ChenAbstractMicroRNA-mediated posttranscriptional regulation is an important epigenetic regulatory mechanism of gene expression, and its dysregulation is involved in the development and progression of a variety of malignancies, including chronic myeloid leukemia (CML). The BCR-ABL1 fusion gene is not only the initiating...
Wed Sep 11, 2019 17:05
Key points There is a close relationship between skeletal muscle physiology and Ca2+/CaM signalling. Despite the effects of Ca2+/CaM signalling on immune and inflammatory responses have been extensively explored, few studies have investigated the role of CaM pathway activation on the post‐injury muscle inflammatory response. In this study, we investigated the role of CaM‐dependent signalling in muscle inflammation in cardiotoxin induced myoinjuries in mice. The CaMKII, CaMKIV and NFAT pathways...
Wed Sep 11, 2019 17:05
DETERMINING THE DOSE RATE DEPENDENCE OF DIFFERENT ACTIVE PERSONAL DOSEMETERS IN STANDARDIZED PULSED AND CONTINUOUS RADIATION FIELDS. Radiat Prot Dosimetry. 2019 Sep 03;: Authors: Hupe O, Friedrich S, Vanhavere F, Brodecki M Abstract In 2016, the EURADOS working group 12 started a project to gather reliable data concerning the behavior of active personal dosemeters (APDs) used by European hospitals in standardized pulsed and hospital fields. This paper...
Wed Sep 11, 2019 17:06
Abstract Introduction With expanding scope of interventions it becomes mandatory to have correct and evidence-based knowledge of surface anatomy of internal abdominal structures. Information available in text books is derived from work done on cadaveric studies. Current study was designed to provide data of key abdominal surface anatomical landmarks and their variations in living subjects using CT imaging of adult population. ...
Wed Sep 11, 2019 03:00
Related ArticlesLong noncoding RNA MALAT1 knockdown inhibits progression of anaplastic thyroid carcinoma by regulating miR-200a-3p/FOXA1. Cancer Biol Ther. 2019 Sep 10;:1-11 Authors: Gou L, Zou H, Li B Abstract Long noncoding RNAs (lncRNAs) have been reported to play essential roles in progression of thyroid carcinoma. However, the roles of lncRNA metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) in anaplastic thyroid carcinoma (ATC) process...
Wed Sep 11, 2019 17:13
Background Many patients with human papillomavirus (HPV)–related head and neck squamous cell carcinoma (HPV‐HNSCC) initially present with cervical lymph node metastases. Although p16 immunohistochemistry (IHC) is the most commonly used surrogate marker for HPV, however criteria in cytologic material are not well established. The objective of this study was to better characterize p16 IHC in cell blocks of metastatic HPV‐HNSCC, and to evaluate the performance of HPV RNA in situ hybridization (RNA...
Wed Sep 11, 2019 15:59
Publication date: Available online 10 September 2019Source: Behavioural Brain ResearchAuthor(s): Sabrina Salberg, Himanthri Weerwardhena, Reid Collins, Raylene A. Reimer, Richelle MychasiukABSTRACTMild traumatic brain injury (mTBI), caused by an insult to the head, results in a cascade of molecular imbalance that includes altered glucose metabolism, mitochondrial dysfunction, and increases in reactive oxygen species. Although glucose is the primary energy source for the brain, it becomes an inefficient...
Wed Sep 11, 2019 17:32
Publication date: Available online 10 September 2019Source: Behavioural Brain ResearchAuthor(s): Maarten van den Buuse, Laetitia Buret, Rachel HillAbstractBrain-derived neurotrophic factor (BDNF) has been implicated in cognition and the effects of chronic stress. We have previously shown in mice that chronic adolescent treatment with corticosterone (CORT), to simulate stress, resulted in spatial memory deficits and markedly elevated levels of the N-methyl-D-aspartate (NMDA) receptor subunit NR2B...
Wed Sep 11, 2019 17:32
Publication date: Available online 10 September 2019Source: Behavioural Brain ResearchAuthor(s): Ewa SiucinskaAbstractThis review assesses the parallel literature on the role of gamma - aminobutyric acid (GABA) in brain plasticity and GABA elements dysfunction related disorders. I review historical and new data from both animal and human sources which have helped define the key role for this transmitter synthesis, release and reuptake, GABA receptors subtype regulation, and GABAergic neurons function...
Wed Sep 11, 2019 17:32
Publication date: Available online 11 September 2019Source: Behavioural Brain ResearchAuthor(s): Kyosuke Uno, Hajime Miyanishi, Kengo Sodeyama, Toshiyuki Fujiwara, Toh Miyazaki, Shi-ichi Muramatsu, Atsumi NittaAbstractThe number of patients with depressive disorders is increasing. However, the mechanism of depression onsets has not been completely revealed. We previously identified Shati/Nat8l, an N-acetyltransferase, in the brain using an animal model of psychosis. In this study, we revealed the...
Wed Sep 11, 2019 17:32
Bangladesh Fistula Mission Partnership: Leveraging Assets from the United States Agency for International Development and the Department of Defense to Address a Health Care Crisis in a Developing Nation. Mil Med. 2019 Sep 10;: Authors: Gehrich AP, Dietrich C, Licina D, Satin M, Ahmed S, Huda N Abstract INTRODUCTION: Obstetric fistulae are a leading scourge for women in developing countries resulting, in severe individual suffering and devastating socio-economic...
Wed Sep 11, 2019 17:40
Horner's Syndrome with Unilateral Brachial Plexus Blockade Mimicking Cerebrovascular Accident Following Lumbar Combined Spinal Epidural Analgesia for Labor. Mil Med. 2019 Aug 29;: Authors: Bennett RJ, Wooten A, Babbel L, Reel BA Abstract Horner's Syndrome (HS) with brachial plexus involvement following lumbar epidural anesthesia may be a startling event for the patient and providers. We present a case of Horner's Syndrome and complete brachial plexus...
Wed Sep 11, 2019 17:40
Relationship Between Spiritual Well-being and Post-traumatic Stress Disorder Symptoms in United States Air Force Remotely Piloted Aircraft and Intelligence Personnel. Mil Med. 2018 Sep 01;183(9-10):e489-e493 Authors: Wood JD, Ware CM, Correll T, Heaton JE, McBride T, Haynes JT Abstract BACKGROUND: Remotely piloted aircraft (RPA) are in frequent use by the U.S. Air Force to engage in combat operations from remote locations. RPA operations involve remote...
Wed Sep 11, 2019 17:40
Thyroid, Ahead of Print.
Wed Sep 11, 2019 10:00
Publication date: Available online 10 September 2019Source: Dental MaterialsAuthor(s): Marilia M.A.C. Velo, Tatiana R.L. Nascimento, Cassiana K. Scotti, Juliana F.S. Bombonatti, Adilson Y. Furuse, Vinícius D. Silva, Thiago A. Simões, Eliton S. Medeiros, Jonny J. Blaker, Nikolaos Silikas, Rafael F.L. MondelliAbstractObjectivesIn this study hybrid nanofibers embedded with niobium pentoxide (Nb2O5) were synthesized, incorporated in self-adhesive resin cement, and their influence on physical-properties...
Wed Sep 11, 2019 17:46
Publication date: Available online 10 September 2019Source: World NeurosurgeryAuthor(s): Nader Delavari, Ndi Geh, Shawn L. Hervey-Jumper, Erin L. McKean, Stephen E. SullivanAbstractBackgroundSynovial cysts are cystic masses lined with pseudostratified columnar cells and contain clear or xanthochromic fluid. Though commonly encountered in the lumbar spine, synovial cysts infrequently occur in the cervical spine and rarely involve the odontoid process. The etiology of synovial cysts of the odontoid...
Wed Sep 11, 2019 17:59
Publication date: Available online 10 September 2019Source: World NeurosurgeryAuthor(s): G. Muscas, F. Battista, G. Lastrucci, A. Della PuppaAbstractBackgroundLesions arising or abutting in the posterior half of the III ventricle are approached through established routes to avoid damage of essential brain structures. Occasionally, the features of the lesion require rethinking these traditional routes and tailoring the surgical approach to cause fewer debilitating sequelae to the patient. We introduce...
Wed Sep 11, 2019 17:59
Publication date: November 2019Source: World Neurosurgery, Volume 131Author(s): Eiji Higashi, Taketo Hatano, Mitsushige Ando, Hideo Chihara, Takenori Ogura, Keita Suzuki, Keitaro Yamagami, Daisuke Kondo, Takahiko Kamata, Shota Sakai, Hiroki Sakamoto, Izumi NagataBackgroundAntiplatelet agents are typically administered before and after treatment using flow-diverter stents (FDS) to prevent thrombotic complications, but the effects of anticoagulants are unclear. We present a patient with a giant aneurysm...
Wed Sep 11, 2019 17:59
Zusammenfassung Hintergrund Die Studienlage zu Kautabak und Zigarettenrauch ist eindeutig und zeigt karzinogenes Potenzial. Über Schnupftabak ist hingegen wenig bekannt, v. a. auf zellulärer Ebene gibt es keine ausreichenden wissenschaftlichen Publikationen. Somit lässt sich die eventuell mutagene Wirkung von Schnupftabak nur schwer einschätzen. In Konsequenz stützt sich die WHO in ihrer Einstufung des Schnupftabaks als nicht karzinogen...
Wed Sep 11, 2019 03:00
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