Related ArticlesLower doses to hippocampi and other brain structures for skull-base meningiomas with intensity modulated proton therapy compared to photon therapy. Radiother Oncol. 2019 Sep 12;: Authors: Florijn MA, Sharfo AWM, Wiggenraad RGJ, van Santvoort JPC, Petoukhova AL, Hoogeman MS, Mast ME, Dirkx MLP Abstract BACKGROUND AND PURPOSE: Radiotherapy of skull-base meningiomas is challenging due to the close proximity of multiple sensitive organs at...
Related ArticlesRBE-weighted doses in target volumes of chordoma and chondrosarcoma patients treated with carbon ion radiotherapy: Comparison of local effect models I and IV. Radiother Oncol. 2019 Sep 12;: Authors: Gillmann C, Jäkel O, Karger CP Abstract BACKGROUND AND PURPOSE: To compare the relative biological effectiveness (RBE)-weighted dose distributions in the target volume of chordoma and chondrosarcoma patients when using two different versions...
Related ArticlesProton therapy following induction chemotherapy for pediatric and adolescent nasopharyngeal carcinoma. Pediatr Blood Cancer. 2019 Sep 16;:e27990 Authors: Uezono H, Indelicato DJ, Rotondo RL, Sandler ES, Katzenstein HM, Dagan R, Mendenhall WM, Mailhot Vega R, Brennan BM, Bradley JA Abstract PURPOSE: In children treated for nasopharyngeal carcinoma, proton therapy and postchemotherapy target volumes can reduce the radiation dose to developing...
Related ArticlesIntravascular Papillary Endothelial Hyperplasia of the Pineal Region: A Case Report and Review of the Literature. World Neurosurg. 2019 Sep 13;: Authors: Retzlaff AA, Arispe K, Cochran EJ, Zwagerman NT Abstract Intravascular papillary endothelial hyperplasia (IPEH) is a benign vascular lesion that is uncommon in the central nervous system. Reports of central nervous system involvement include intraparenchymal, sellar, cerebellar, brainstem,...
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Related ArticlesUndernutrition at PICU Admission Is Predictor of 60-Day Mortality and PICU Length of Stay in Critically Ill Children. J Acad Nutr Diet. 2019 Sep 12;: Authors: Ventura JC, Hauschild DB, Barbosa E, Bresolin NL, Kawai K, Mehta NM, Moreno YMF Abstract BACKGROUND: There are few studies that assess the role of different nutritional assessment variables at pediatric intensive care unit (PICU) admission in predicting clinical outcomes. ...
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Related ArticlesPediatric Clival Chordoma: A Curable Disease that Conforms to Collins' Law. Neurosurgery. 2018 05 01;82(5):652-660 Authors: Rassi MS, Hulou MM, Almefty K, Bi WL, Pravdenkova S, Dunn IF, Smith TR, Al-Mefty O Abstract BACKGROUND: Skull base chordomas in children are extremely rare. Their course, management, and outcome have not been defined. OBJECTIVE: To describe the preeminent clinical and radiological features in a series of...
Related ArticlesClinical Characteristics of Intravenous PEG-Asparaginase Hypersensitivity Reactions in Patients Undergoing Treatment for Acute Lymphoblastic Leukemia [Formula: see text]. J Pediatr Oncol Nurs. 2018 Mar/Apr;35(2):103-109 Authors: Browne EK, Moore C, Sykes A, Lu Z, Jeha S, Mandrell BN Abstract BACKGROUND: Asparaginase poses a substantial risk for hypersensitivity reactions during and after administration; however, these reactions vary...
Related ArticlesTreating malignant melanoma when a rare BRAF V600M mutation is present: case report and literature review. Rom J Intern Med. 2018 Jun 01;56(2):122-126 Authors: Popescu A, Haidar A, Anghel RM Abstract Recent years have brought major advances in the treatment of malignant melanoma. One such an advance is the treatment with BRAF tyrosine-kinase inhibitors in metastatic malignant melanomas that harbor mutations in the BRAF gene. The trials...
Related ArticlesMetastases from distant primary tumours on the head and neck: clinical manifestation and diagnostics of 91 cases. Oral Maxillofac Surg. 2018 Jun;22(2):119-128 Authors: Baum SH, Mohr C Abstract PURPOSE: The aim of this study was to evaluate which primary tumours metastasize on the head and neck region, identify the kind of clinical manifestation, the types of diagnostics that should be performed, and prove that the therapy appears possible...
Related ArticlesThe Robust Potential of Mesenchymal Stem Cell-Loaded Constructs for Hard Tissue Regeneration After Cancer Removal. Adv Exp Med Biol. 2019;1084:17-43 Authors: Hosseini S, Shamekhi MA, Jahangir S, Bagheri F, Eslaminejad MB Abstract Malignant bone tumors, although quite rare, are one of the causes of death in children and adolescents. Surgery as a common and primary treatment for removal of virtually bone cancer cause large bone defects....
Characterization of liver injury induced by cancer immunotherapy using immune checkpoint inhibitors.
Related ArticlesCharacterization of liver injury induced by cancer immunotherapy using immune checkpoint inhibitors. J Hepatol. 2018 06;68(6):1181-1190 Authors: De Martin E, Michot JM, Papouin B, Champiat S, Mateus C, Lambotte O, Roche B, Antonini TM, Coilly A, Laghouati S, Robert C, Marabelle A, Guettier C, Samuel D Abstract BACKGROUND & AIMS: Immunotherapy for metastatic cancer can be complicated by the onset of hepatic immune-related adverse...
Related ArticlesComprehensive analysis of the MLH1 promoter region in 480 patients with colorectal cancer and 1150 controls reveals new variants including one with a heritable constitutional MLH1 epimutation. J Med Genet. 2018 04;55(4):240-248 Authors: Morak M, Ibisler A, Keller G, Jessen E, Laner A, Gonzales-Fassrainer D, Locher M, Massdorf T, Nissen AM, Benet-Pagès A, Holinski-Feder E Abstract BACKGROUND: Germline defects in MLH1, MSH2, MSH6 and PMS2...
Related ArticlesTenosynovial Giant Cell Tumors in Children: A Similar Entity Compared With Adults. Clin Orthop Relat Res. 2018 09;476(9):1803-1812 Authors: Mastboom MJL, Verspoor FGM, Uittenbogaard D, Schaap GR, Jutte PC, Schreuder HWB, van de Sande MAJ Abstract BACKGROUND: Tenosynovial giant cell tumor (TGCT) is a rare, benign, monoarticular entity. Many case-series in adults are described, whereas TGCT is only incidentally reported in children. Therefore,...
Related ArticlesPleural myopericytoma: A rare neoplasm in a difficult location. J Thorac Cardiovasc Surg. 2018 08;156(2):e129-e131 Authors: Hodges K, Zou Y, Everett A, Murthy S, Ahmad U PMID: 29510931 [PubMed - indexed for MEDLINE]
Related ArticlesAn Uncommon Cutaneous Lesion. JAMA Otolaryngol Head Neck Surg. 2018 Apr 01;144(4):377-378 Authors: Clark CM, Muro-Cacho C, Ridley MB PMID: 29522143 [PubMed - indexed for MEDLINE]
Related ArticlesPatterns of care and survival outcomes in patients with an extraventricular neurocytoma: An individual patient data analysis of 201 cases. Neurol India. 2018 Mar-Apr;66(2):362-367 Authors: Mallick S, Benson R, Rath GK Abstract Introduction:: Extraventricular neurocytoma is a rare neuronal tumor arising outside the ventricles. However, because of its rarity, its optimum treatment remains undefined. Materials and Methods: We intended...
Related ArticlesEarly brain metastasis of advanced gastric cancer with a pathological complete response to neoadjuvant chemotherapy followed by surgery: A case report and literature review. Cancer Biol Ther. 2018;19(10):875-878 Authors: Luo H, Peng L, Wang N, Zhang J, Zheng X, Sun Y, Fan C, Ge H Abstract Advanced gastric cancer with a pathological complete response to neoadjuvant chemotherapy and surgery followed by early brain metastasis is rare....
Related ArticlesA rare association of Gorlin-Goltz syndrome. Neurol India. 2018 May-Jun;66(3):847-849 Authors: Kumar S, Eshanth R, Indiran V, Mariappan K, Maduraimuthu P PMID: 29766957 [PubMed - indexed for MEDLINE]
Related ArticlesAnaplastic astrocytoma and pituitary macroadenoma within the same patient: A rare case of intracranial collision tumor. Neurol India. 2018 May-Jun;66(3):857-860 Authors: Naik H, Vernon V, Gade P, Bhople L, Guha A PMID: 29766961 [PubMed - indexed for MEDLINE]
Related ArticlesFlow cytometric analysis of extracellular vesicle subsets in plasma: impact of swarm by particles of non-interest. J Thromb Haemost. 2018 07;16(7):1423-1436 Authors: Libregts SFWM, Arkesteijn GJA, Németh A, Nolte-'t Hoen ENM, Wauben MHM Abstract Essentials Extracellular vesicles (EVs) in biological fluids are promising biomarkers for disease. Fluorescence-based flow cytometric analysis is suitable to detect low abundant EV subsets. Particles...
Related ArticlesSafety Analysis of Brentuximab Vedotin from the Phase III AETHERA Trial in Hodgkin Lymphoma in the Post-Transplant Consolidation Setting. Biol Blood Marrow Transplant. 2018 11;24(11):2354-2359 Authors: Nademanee A, Sureda A, Stiff P, Holowiecki J, Abidi M, Hunder N, Pecsok M, Uttarwar M, Purevjal I, Sweetenham J Abstract The phase III AETHERA trial demonstrated the efficacy of brentuximab vedotin (BV) as consolidation therapy in patients...
Related ArticlesHemophagocytic Lymphohistiocytosis in Cutaneous T-Cell Lymphoma. JAMA Dermatol. 2018 07 01;154(7):828-831 Authors: Lee DE, Martinez-Escala ME, Serrano LM, Zhou XA, Kaplan JB, Pro B, Choi J, Guitart J Abstract Importance: Hemophagocytic lymphohistiocytosis (HLH) has been reported as a serious complication of cutaneous T-cell lymphoma (CTCL). Despite available diagnostic guidelines, it remains a diagnostic and therapeutic challenge in...
Related ArticlesImpact of fluoroquinolone prophylaxis during neutropenia on bloodstream infection: Data from a surveillance program in 8755 patients receiving high-dose chemotherapy for haematologic malignancies between 2009 and 2014. J Infect. 2018 07;77(1):68-74 Authors: Kern WV, Weber S, Dettenkofer M, Kaier K, Bertz H, Behnke M, Weisser M, Götting T, Widmer AF, Theilacker C, Hospital Infection Surveillance System for Patients with Haematologic/Oncologic Malignancies...
Related ArticlesInterpretation Difficulties of Serum Immunofixation Test in Immunoglobulin D Multiple Myeloma with Hidden Lambda Light Chains. Clin Lab. 2018 Jun 01;64(6):1065-1069 Authors: Biaz A, Uwingabiye J, Rachid A, Dami A, Bouhsain S, Ouzzif Z, Idrissi SEM Abstract BACKGROUND: We report a case of immunoglobulin (Ig) D myeloma with hidden lambda light chains in a patient whose immunofixation test was very difficult to interpret: the IgD reacts...
Related ArticlesMutational landscape and clonal diversity of pulmonary adenoid cystic carcinoma. Cancer Biol Ther. 2018;19(10):898-903 Authors: Li M, Zhao BR, Liu SQ, An J, Deng PB, Han-Zhang H, Ye JY, Mao XR, Chuai SK, Hu CP Abstract Pulmonary adenoid cystic carcinoma is a rare and indolent lung malignancy, characterized by a protracted but unpredictable growth behavior. Currently, the treatment of PACC relies on surgery and local radiotherapy. However,...
Related ArticlesBreast Implant-Associated Anaplastic Large Cell Lymphoma: Immediate or Delayed Implant Replacement? Aesthetic Plast Surg. 2018 Dec;42(6):1492-1498 Authors: Shine JJ, Boghossian E, Beauchemin G, Papanastasiou VW, Borsuk DE Abstract INTRODUCTION: Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a rare and recently described type of peripheral T-cell lymphoma. Fewer than 550 cases have been reported worldwide. Although...
Related ArticlesPrevalence Estimates of Polycystic Kidney and Liver Disease by Population Sequencing. J Am Soc Nephrol. 2018 10;29(10):2593-2600 Authors: Lanktree MB, Haghighi A, Guiard E, Iliuta IA, Song X, Harris PC, Paterson AD, Pei Y Abstract BACKGROUND: Estimating the prevalence of autosomal dominant polycystic kidney disease (ADPKD) is challenging because of age-dependent penetrance and incomplete clinical ascertainment. Early studies estimated...
Related ArticlesThe In Situ Sulfidation of Cu2 O by Endogenous H2 S for Colon Cancer Theranostics. Angew Chem Int Ed Engl. 2018 11 26;57(48):15782-15786 Authors: An L, Wang X, Rui X, Lin J, Yang H, Tian Q, Tao C, Yang S Abstract Expression of a high concentration of H2 S is closely related to the formation of colon cancer tumors. However, only a few H2 S-triggered theranostics agents for colon cancer have been reported to date. Now, a turn-on theranostics...
Related ArticlesInappropriate Laughter and Behaviours: How, What, and Why? Case of an Adult with Undiagnosed Gelastic Seizure with Hypothalamic Hamartoma. Hawaii J Med Public Health. 2018 12;77(12):319-324 Authors: Beckwith NL, Khil JC, Teng J, Liow KK, Smith A, Luna J Abstract Gelastic seizures (GS) are a rare form of epilepsy characterized by inappropriate, uncontrolled laughter. They are highly associated with abnormal cognitive development and behavioral...
Related ArticlesTemporal-occipital glioblastoma presenting with Alice in Wonderland Syndrome in a patient with a long-time history of migraine without aura. Neurocase. 2018 Oct - Dec;24(5-6):242-244 Authors: Mastria G, Mancini V, Viganò A, De Sanctis R, Letteri F, Toscano M, Di Piero V Abstract Alice in Wonderland Syndrome (AIWS) is a rare perceptual disorder characterized by an erroneous perception of the body or the surrounding space. AIWS may be caused...
Related ArticlesPrimary Hepatic Neuroendocrine Carcinoma Treated with Doxorubicin and Cyclophosphamide in a Dog. J Am Anim Hosp Assoc. 2019 May/Jun;55(3):e55305 Authors: Morgan E, O'Connell K, Thomson M, Boyd S, Sandy J Abstract A 7 yr, 6 mo old male neutered Australian cattle dog cross presented to a referral hospital with a large abdominal mass. An abdominal ultrasound revealed multifocal lesions throughout the liver, which were suspicious for intrahepatic...
Related ArticlesAcromegaly. Nat Rev Dis Primers. 2019 03 21;5(1):20 Authors: Colao A, Grasso LFS, Giustina A, Melmed S, Chanson P, Pereira AM, Pivonello R Abstract Acromegaly is characterized by increased release of growth hormone and, consequently, insulin-like growth factor I (IGF1), most often by a pituitary adenoma. Prolonged exposure to excess hormone leads to progressive somatic disfigurement and a wide range of systemic manifestations that are...
Related Articles[Other specific types of diabetes and exocrine pancreatic insufficiency (Update 2019)]. Wien Klin Wochenschr. 2019 May;131(Suppl 1):16-26 Authors: Kaser S, Winhofer-Stöckl Y, Kazemi-Shirazi L, Hofer SE, Brath H, Sourij H, Vila G, Abrahamian H, Riedl M, Weitgasser R, Resl M, Clodi M, Luger A Abstract The heterogenous catagory "specific types of diabetes due to other causes" encompasses disturbances in glucose metabolism due to other endocrine...
Related ArticlesMetastatic SMARCB1 (INI-1)-Deficient Sinonasal Carcinoma Diagnosed by Endobronchial Ultrasound-Guided Fine-Needle Aspiration (EBUS-FNA): A Potential Diagnostic Pitfall and Review of the Literature. Acta Cytol. 2019;63(5):431-437 Authors: McHugh KE, Policarpio-Nicolas MLC Abstract SMARCB1 (INI-1)-deficient sinonasal carcinoma is a rare entity within the subgroup of poorly differentiated sinonasal tract carcinomas. As there are only two...
Related Articles[Surgical treatment of pulmonary trunk malignancy]. Khirurgiia (Mosk). 2019;(7):10-14 Authors: Parshin VD, Komarov RN, Chernyavskiy SV, Simonyan AO Abstract Surgical treatment of a patient with primary sarcoma of pulmonary trunk is presented in the article. This rare disease is characterized by poor prognosis if early diagnosis and adequate surgical treatment are absent.PMID: 31355808 [PubMed - indexed for MEDLINE]
Related Articles[Mediastinal pancreatic cysts: review and own clinical observations]. Khirurgiia (Mosk). 2019;(7):80-86 Authors: Kotelnikova LP, Plaksin SA, Farshatova LI Abstract OBJECTIVE: To present the results of surgical treatment of patients with mediastinalpancreatogeniccysts (MPC). MATERIAL AND METHODS: There were 5 patients with MPC. RESULTS: Laboratory tests revealed increased blood amylase level by 1.5-2 times in 3 cases,...
Related ArticlesEpithelioid hemangioendothelioma arising from the kidney: A rare case report. Medicine (Baltimore). 2019 Aug;98(34):e16537 Authors: Liu Y, Liu A, Wu J, Liu T Abstract RATIONALE: Primary renal epithelioid hemangioendothelioma (EH) is a rare vascular tumor with intermediate biologic behavior and metastatic potential, and it is extremely rare and has only 4 cases in the current literatures. PATIENT CONCERNS: We reported a 30-year-old...
Related ArticlesPineal region metastasis with intraventricular seeding: A case report and literature review. Medicine (Baltimore). 2019 Aug;98(34):e16652 Authors: Ji J, Gu C, Zhang M, Zhang H, Wang H, Qu Y, Ren M, Ning W, Yu C Abstract INTRODUCTION: Tumors of the pineal region are rare, and metastatic carcinoma occurring in the pineal region is extremely rare. No previous reports have described pineal region metastasis with intraventricular seeding....
Related ArticlesBrain metastases from esophageal cancer: A retrospective analysis of the outcome after surgical resection followed by radiotherapy. Medicine (Baltimore). 2019 Aug;98(34):e16653 Authors: Stavrinou P, Plambeck L, Proescholdt M, Ghadimi M, Goldbrunner R, Grau S Abstract Brain metastases deriving from esophageal cancer are very rare with scarce data available concerning these patients' outcome. We, therefore, evaluated outcome after surgical...
Related ArticlesExtranodal natural killer/T-cell lymphoma nasal type with central nervous system involvement mimicked tuberculous meningitis: A case report. Medicine (Baltimore). 2019 Aug;98(34):e16747 Authors: Yang Y, Li Z, Zhiyang C, Liang H Abstract RATIONALE: Neurologic deficits are rare in patients with extranodal natural killer/T-cell lymphoma (NKTL), nasal type. We present a case that was initially suspected as tuberculous meningitis, but later...
Related ArticlesManagement of tumor rupture and abdominal compartment syndrome in an infant with bilateral high risk stage 4 neuroblastoma: A case report. Medicine (Baltimore). 2019 Aug;98(34):e16752 Authors: Lode HN, Henze G, Siebert N, Ehlert K, Barthlen W Abstract RATIONALE: Tumor rupture and bleeding at initial presentation of infants with neuroblastoma (NBL) is a rare, but life threatening condition and challenge in pediatric oncology. Here, we...
Related ArticlesTargeting CSC in a Most Aggressive Subtype of Breast Cancer TNBC. Adv Exp Med Biol. 2019;1152:311-334 Authors: Bao B, Prasad AS Abstract Triple negative breast cancer (TNBC) is a more aggressive subtype of breast cancer and is characteristic of the absence of the expressions of estrogen receptor, progesterone receptor, and human epithelial growth factor receptor 2 in breast tumor tissues. This subtype of breast cancer has the poorest...
Related ArticlesBleeding with negative coagulation screening test as initial presentation of chronic myelogenous leukemia managed by fresh frozen plasma: A case report. Medicine (Baltimore). 2019 Aug;98(35):e16984 Authors: Wang Y, Wang L, Xi Y, Li Z Abstract INTRODUCTION: Chronic myelogenous leukemia (CML), a clonal disorder of pluripotent stem cell, rarely presents with bleeding in chronic phase due to the function preservation of the platelets. Factor...
Related ArticlesSurgical treatment of giant chordoma in the thoracic spine combining thoracoscopic and posterior spinal surgery: A case report. Medicine (Baltimore). 2019 Aug;98(35):e16990 Authors: Liu S, Zhou X, Song A, Huo Z, Yao S, Wang Y, Liu Y Abstract RATIONALE: Giant thoracic chordoma is a highly unusual disease with no standard curative managements yet. The objective of this study is to report a very rare case of giant thoracic chordoma successfully...
Related ArticlesDown syndrome with primary thyroid diffuse large B-cell lymphoma and Hashimoto thyroiditis: A CARE compliant case report. Medicine (Baltimore). 2019 Aug;98(35):e16994 Authors: Wei L, Zhao N, Li Y, Zheng X, Zhang H, Zhang Z Abstract RATIONALE: Adult patients with Down syndrome (DS) commonly develop Hashimoto thyroiditis (HT). However, primary diffuse large B-cell lymphoma (DLBCL) of the thyroid is uncommon, and its simultaneous occurrence...
Related ArticlesTreatment of syncope in tongue cancer with palliative chemotherapy in the intensive care unit: A case report. Medicine (Baltimore). 2019 Aug;98(35):e16998 Authors: Fang C, Yang L, Zeng G, Huang R, Fang W, Chen Y, Guan J, Li P, Huang X, Lin L Abstract RATIONALE: Syncope caused by head and neck cancer (HNC) is rare. However, syncope caused by tongue cancer (TC) is even rarer. In TC, syncope is caused by tumor-mediated compression of the...
Related ArticlesA series of 10 malignant triton tumors in one institution. Medicine (Baltimore). 2019 Sep;98(36):e16797 Authors: Bian Y, Yongbo X, Xi Z, Zhao D, Wu H, Liu Y Abstract Malignant triton tumor (MTT) is an extraordinarily uncommon and aggressive tumor which have poor prognosis. Malignant peripheral nerve sheath tumors with additional rhabdomyoblasts are found in MTT histologically. The prognosis of patients is poor. The goal of our study...
Related ArticlesClinical features and prognostic analysis of patients with chest wall chondrosarcoma. Medicine (Baltimore). 2019 Sep;98(36):e17025 Authors: Gao H, Zhou Y, Wang Z, Zhao R, Qian S Abstract Chest wall chondrosarcoma is a rare malignant tumor of the bone. This study is aimed to identify the prognostic determinants of chest wall chondrosarcoma. We used the Surveillance, Epidemiology, and End Results (SEER) database to identify patients with...
Related ArticlesOrbital neuroblastoma metastasis: A case report and literature review. Medicine (Baltimore). 2019 Sep;98(36):e17038 Authors: Yang WJ, Zhou YY, Zhao F, Mei ZM, Li S, Xiang Y Abstract RATIONALE: Neuroblastoma is one of the most common tumors found in children, and mostly arises in the adrenal gland and paravertebral regions. Orbital neuroblastoma metastasis is relatively rare, and is associated with poor prognosis. Since the symptoms and...
Related ArticlesMucosa-associated lymphoid tissue lymphoma of the accessory parotid gland presenting as a simple cheek mass: A case report. Medicine (Baltimore). 2019 Sep;98(36):e17042 Authors: Hwang JH, Kim DW, Kim KS, Lee SY Abstract RATIONALE: Mucosa-associated lymphoid tissue (MALT) lymphoma, also known as extranodal marginal zone B-cell lymphoma, usually occurs in the gastric mucosa, lung, lacrimal glands, and salivary glands. MALT lymphoma arising...
Related ArticlesColorectal Cancer Outcomes in a Large Negative Computed Tomography Colonography Screening Cohort. Can Assoc Radiol J. 2019 Sep 12;: Authors: McComiskey DA, Barrett B, Flemming J, McKay K, Sala E Abstract INTRODUCTION: At our institution, the most common cohort of individuals having computed tomography colonography (CTC) are those that require primary screening for colorectal cancer and were unable to tolerate or failed optical colonoscopy...
Related ArticlesPrimary Pulmonary Involvement in Mucosa-associated Lymphoid Tissue Lymphoma. Cureus. 2019 Jul 09;11(7):e5110 Authors: Jhaveri K, Dimas DJ, Vakil A, Surani S Abstract Pulmonary nodules have a broad differential diagnosis with primary lung cancer, lung metastases, benign tumors, carcinoid tumors, and infectious granulomas as their common cause. While relatively rare, pulmonary lymphoproliferative disorders such as primary pulmonary lymphomas,...
Related ArticlesNational Trends and Hospitalizations Related to Pancreatic Cancer in Acute Pancreatitis Patients: A Nationwide Inpatient Sample Study. Cureus. 2019 Jul 17;11(7):e5155 Authors: Gayam V, Sidhu JS, Mandal A, Garlapati P, Adapa S, Konala VM, Naramala S, Then EO, Maddika S, Gaduputi V Abstract Background Pancreatic cancer (PC) is one of the common cancers in the United States (U.S.) and is associated with high mortality and morbidity. In spite...
Related ArticlesMalignant peripheral nerve sheath tumors: Analysis of the national cancer database. Oral Oncol. 2019 Sep 13;98:13-19 Authors: Mowery A, Clayburgh D Abstract OBJECTIVES: Malignant peripheral nerve sheath tumor (MPNST) is a rare type of soft tissue sarcoma (STS) that carries significant mortality. Given the rarity of MPNST, current knowledge on the disease is limited. We aim to characterize patient, tumor, and treatment factors, and determine...
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Related ArticlesBrain metastases. Nat Rev Dis Primers. 2019 01 17;5(1):5 Authors: Achrol AS, Rennert RC, Anders C, Soffietti R, Ahluwalia MS, Nayak L, Peters S, Arvold ND, Harsh GR, Steeg PS, Chang SD Abstract An estimated 20% of all patients with cancer will develop brain metastases, with the majority of brain metastases occurring in those with lung, breast and colorectal cancers, melanoma or renal cell carcinoma. Brain metastases are thought to occur...
Related ArticlesEvolving Role of Systemic Therapies in Non-melanoma Skin Cancer. Clin Oncol (R Coll Radiol). 2019 Sep 12;: Authors: Conforti C, Corneli P, Harwood C, Zalaudek I Abstract Keratinocyte cancers - basal and cutaneous squamous cell carcinoma (BCC, cSCC) - are the most common forms of non-melanoma skin cancer (NMSC) and there has been a significant increase in their incidence globally in recent decades. Although the majority of BCC and cSCC...
Related ArticlesMulti-omic approaches to improve outcome for T-cell acute lymphoblastic leukemia patients. Adv Biol Regul. 2019 Aug 26;:100647 Authors: van der Zwet JCG, Cordo' V, Canté-Barrett K, Meijerink JPP Abstract In the last decade, tremendous progress in curative treatment has been made for T-ALL patients using high-intensive, risk-adapted multi-agent chemotherapy. Further treatment intensification to improve the cure rate is not feasible as...
Related ArticlesDevelopment of c‑MET‑specific chimeric antigen receptor‑engineered natural killer cells with cytotoxic effects on human liver cancer HepG2 cells. Mol Med Rep. 2019 Jul 25;: Authors: Liu B, Liu ZZ, Zhou ML, Lin JW, Chen XM, Li Z, Gao WB, Yu ZD, Liu T Abstract In recent years, cellular immunotherapy has served an important role in the combined treatment of hepatocellular carcinoma. The possibility of specific cell therapies for the treatment...
Related ArticlesClinical features of neuroendocrine prostate cancer. Eur J Cancer. 2019 Sep 13;121:7-18 Authors: Conteduca V, Oromendia C, Eng KW, Bareja R, Sigouros M, Molina A, Faltas BM, Sboner A, Mosquera JM, Elemento O, Nanus DM, Tagawa ST, Ballman KV, Beltran H Abstract BACKGROUND: Neuroendocrine prostate cancer (NEPC) is an aggressive variant of prostate cancer that may arise de novo or in patients previously treated with hormonal therapies for...
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