Detecting and treating schizophrenia early, perhaps even before symptoms arise, could lead to better therapeutic outcomes. Studies have demonstrated differences in social function and cognition among people who later develop symptoms of schizophrenia, but less is known about pre-morbid temperament and personality.
For many people, simple sensations such as the gentle caress of a loved one or walking barefoot through the grass feel pleasant. For individuals with autism, the feeling of light pressure on the skin may be perceived as aversive or even cringe-inducing.
A new study from researchers at Max Planck Florida Institute for Neuroscience (MPFI) has shed light on the unexpected mechanism that allows calcium/calmodulin-dependent protein kinase, or CaMKII, to decode and translate calcium signaling in the brain. Using advanced imaging techniques and novel biosensors, Ryohei Yasuda, Ph.D. and his team have revealed new insights into CaMKII's activity at the single-synapse level.
Due to the increasing insulin resistance of cells, patients with type 2 diabetes suffer from increased blood sugar levels with far-reaching consequences. After many years of illness, insulin production dries up and patients have to inject insulin.
Researchers at the São Paulo State Cancer Institute (ICESP) in Brazil have used a genetically manipulated virus to destroy tumor cells upon injection into mice with prostate cancer. The virus also made tumor cells more sensitive to chemotherapy drugs, halting tumor progression and almost eliminating tumors in some cases.
Researchers at Karolinska Institutet in Sweden have studied which genes are expressed in overactive immune cells in mice with asthma-like inflammation of the airways. Their results, which are published in the journal Immunity, suggest that the synthesis and breakdown of fats plays an important part in the process.
In the past few years, thrill-seekers from Hollywood, Silicon Valley and beyond have been travelling to South America to take part in so-called Ayahuasca retreats. Their goal: to partake in a brewed concoction made from a vine plant Banisteriopsis caapi, traditionally used by indigenous people for sacred religious ceremonies. Drinkers of Ayahuasca experience short-term hallucinogenic episodes many describe as life-changing.
Several infections have been identified as possible stroke triggers, with urinary tract infections showing the strongest link with ischemic stroke, according to new research in the American Heart Association's journal Stroke.
Researchers at the University of Toronto have found a consistent cholesterol-lowering effect for soy protein, with pooled data from dozens of clinical trials that span the last two decades.
It's been called the Italian "green gold rush." Mild, barely there marijuana dubbed "cannabis light" has put Italy on the international weed map, producing hundreds of stores that sell pot by the pouch and attention from investors banking the legalization of stronger stuff will follow.
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