Abstract Objective To review the clinical data on the safety and effectiveness of intravenous (IV) and intraventricular (IVT) tigecycline in healthcare-associated Acinetobacter baumannii meningitis and ventriculitis. Methods A literature search was performed in PubMed (from 2005 to December 2018). The bibliographies of the retrieved articles were searched...
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Abstract Purpose of review Dengue virus (DENV) infections are a global health emergency. Humans can experience multiple DENV infections, owing to the presence of four antigenically distinct DENV serotypes, DENV1–4. DENV infection results in a spectrum of disease, ranging from mild and self-limiting to severe and life-threatening illness. Currently, one dengue vaccine is approved, although with modest efficacy, so dengue-directed therapeutics...
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