The Scientific World Journal

The HLA-Cw12 Allele Is an Important Susceptibility Allele for Psoriasis and Is Associated with Resistant Psoriasis in the Turkish Population

Background. Psoriasis is a multifactorial immune-mediated inflammatory disease triggered by both genetic and environmental factors. The strong association between psoriasis and HLA-C06 allele has been demonstrated in various races. The HLA-C12 allele is closely related to the HLA-C06 family of alleles and shares identical sequences. To the best of our knowledge, there is no information about the relationship between HLA-C12 and psoriasis in the Turkish population. The present study aims to determine...

The Scientific World Journal

15h