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Κυριακή 9 Ιουνίου 2019

Prognostic value of endopredict for invasive lobular carcinomas in the combined ABCSG-6/8 and TransATAC trials
I Sestak; M Filipits; R Buus; M Rudas; M Knauer ...
Annals of Oncology, Volume 30, Issue Supplement_3, May 2019, mdz095.001, https://doi.org/10.1093/annonc/mdz095.001
Extract
Background: Invasive lobular carcinoma (ILC) accounts for approximately 15% of all breast cancer cases. Most of the correlations between multigene assays and patient outcome were derived from studies based on mixed cohorts with IDC and ILC. Here, we specifically investigate the prognostic value of Endopredict (EPclin) in a large cohort of ILCs pooled from large phase III randomised trials.

Methods: A total of 2630 breast cancer patients with ER-positive, HER2-negative disease were included in this analysis. The primary objective of this analysis was to determine the prognostic value of EPclin for distant recurrence (DR) in years 0-10 in women with...

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