Polydioxanone (PDS) Sheet as a Rigid Framework in Skull‐Base Repair: Our experience in Thirteen patients
Mohd Afiq Mohd Slim  Hussain Jasem  Louise Melia  Gerald McGarry
First published: 19 June 2019 https://doi.org/10.1111/coa.13391
This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1111/coa.13391
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Abstract
1.Polydiaxanone (PDS) sheet is a viable and safe option as a rigid reinforcement material with nasoseptal flap (NSF) for skull‐base defect following Transsphenoidal Hypophysectomy (TH).

2.PDS sheet is flexible and can be contoured into shape, making it ideal for endoscopic endonasal skull‐base repair using single‐hand instrumentation.

3.PDS's osteoconductive properties could rebuild the natural mucosa‐bone barrier of the defect created following TH.

4.PDS sheet is absorbable and does not incur foreign body inflammatory process from the surrounding area.

5.The perforated PDS sheet could promote healing process by avoiding microvascular compromise secondary to pressure induce micro‐ischaemia.