Delayed hypersensitivity reactions to contrast media

Question 1

Delayed hypersensitivity reactions to iodinated contrast media will most likely present as which of the following?

1. Stevens–Johnson syndrome/toxic epidermal necrolysis.
2. Maculopapular exanthem.
3. Fixed drug eruption.
4. Acute generalized exanthematous pustulosis.
5. Drug‐related eosinophilia and systemic symptoms.

Question 2

Which of the following statements is correct concerning the recurrence of delayed hypersensitivity reactions, such as fixed drug eruption and Stevens–Johnson syndrome/toxic epidermal necrolysis, following subsequent exposure to iodinated contrast media?

1. There is a shorter latency period before recurrence.
2. There is a longer latency period before recurrence.
3. Recurrence usually appears on the trunk.
4. Recurrence usually appears on the abdomen.
5. Recurrence usually appears on the scalp.

Question 3

Of the six cases reported in the literature on drug‐related eosinophilia and systemic symptoms (DRESS) caused by iodinated contrast media how many of them were exposed to contrast media multiple times before manifesting symptoms and signs of DRESS?

1. 0.
2. 2.
3. 4.
4. 5.
5. 6.

Question 4

Which of the following conditions can rarely occur as a delayed hypersensitivity reaction to iodinated contrast media?

1. Behçet disease.
2. Graft‐versus‐host disease.
3. Acanthosis nigrans.
4. Folliculitis.
5. Keratoacanthoma.

Question 5

Iododerma is associated with which of the following extracutaneous manifestations?

1. Conjunctivitis.
2. Swelling of the glands.
3. Swelling of the extremities.
4. Cardiovascular compromise.
5. Abdominal pain.

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