SBRT for pulmonary lesions was a feasible and tolerable option for oligometastatic NSCLC patients. Delivery of SBRT for pulmonary lesions improved outcomes of oligometastatic NSCLC patients. Finally, SBRT combined with first line target therapy might have optimal outcomes. Abstract Purpose The aim of the study was to evaluate the efficacy and safety of stereotactic body radiotherapy (SBRT) for pulmonary lesions in oligometastatic non‐small cell lung cancer (NSCLC) patients, to explore prognostic...
As the first attempt to systemically elucidate N6‐methyladenosine (m6A)'s clinicopathological role in gastric cancer, our work provides insights into the tumor suppressive function of m6A through its negative regulation on Wnt and PI3K/Akt. Abstract Background As the most abundant epigenetic modification on mRNAs and long non‐coding RNAs, N6‐methyladenosine (m6A) modification extensively exists in mammalian cells. Controlled by writers (methyltransferases), readers (signal transducers), and...
A positive peritoneal washing cytology (PWC) during interval debulking surgery was observed to predict earlier disease recurrence in patients with pelvic high‐grade serous carcinoma (HGSC) achieving R0 status. PWC was a simple and effective method to detect clinically significant microscopic residual disease in patients with pelvic HGSC. Abstract Background and Objectives The aim of this study was to determine whether peritoneal washing cytology (PWC) during interval debulking surgery (IDS)...
Abstract Background Although high‐risk human papillomavirus (HR‐HPV) infection is recognized as the main cause of cervical cancer, only a minority of HPV‐infected women develop this malignancy. Increasing evidence suggests that alterations of telomere length might be implicated in carcinogenesis. However, the association between cervical cancer and telomere length remains unknown. Methods This case‐control study included 591 cervical cancer patients and 373 cancer‐free controls, all of...
Consumption of Canton‐style herbal tea was revealed as an independent risk factor associated with elevated antibody levels of VCA‐IgA and EA‐IgA. Smoking was not found only associated with higher antibody levels of EBV DNase‐specific neutralizing antibody but also an apparent risk for advanced NPC diagnosis. Abstract Epstein‐Barr virus (EBV) reactivation, reflected by aberrantly increased levels of various serological antibodies, has been suggested to be an early indicator of nasopharyngeal carcinoma...
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