Biochimie,

Increasing evidence of pathogenic role of the Mediator (MED) complex in the development of cardiovascular diseases

Publication date: Available online 27 June 2019Source: BiochimieAuthor(s): C. Napoli, C. Schiano, A. SoricelliAbstractCardiovascular diseases (CVDs) are the first cause of death in the World. Mediator (MED) is an evolutionarily conserved protein complex, which mediates distinct protein-protein interactions. Pathogenic events in MED subunit have been associated with human diseases. Novel increasing evidence showed that missense mutations in MED13L gene are associated with transposition of great arteries...

ScienceDirect Publication: Biochimie

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