JPM, Vol. 10, Pages 140: A Data-Driven Approach to Carrier Screening for Common Recessive Diseases Journal of Personalized Medicine doi: 10.3390/jpm10030140 Authors: Anna V. Kiseleva Marina V. Klimushina Evgeniia A. Sotnikova Mikhail G. Divashuk Alexandra I. Ershova Olga P. Skirko Olga V. Kurilova Anastasia A. Zharikova Eleonora Yu. Khlebus Irina A. Efimova Maria S. Pokrovskaya Petr A. Slominsky Svetlana A. Shalnova Alexey N. Meshkov Oxana M. Drapkina...
JPM, Vol. 10, Pages 139: Needs of Families with Children with Cerebral Palsy in Latvia and Factors Affecting These Needs Journal of Personalized Medicine doi: 10.3390/jpm10030139 Authors: Dace Bertule Anita Vetra In order to provide targeted support to families who are raising children with developmental disorders, it is important to study the family needs and to understand circumstances that may affect them. The aim of this study was to identify the needs of the families with preschool...
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Life, Vol. 10, Pages 216: Correlation between Expression Profiles of Key Signaling Genes in Colorectal Cancer Samples from Type 2 Diabetic and Non-Diabetic Patients Life doi: 10.3390/life10090216 Authors: Zsuzsanna Elek Zsolt Rónai Gergely Keszler László Harsányi Endre Kontsek Zoltán Herold Magdolna Herold Anikó Somogyi Zsófia Bánlaki Several lines of epidemiological and biochemical evidence support the association of type 2 diabetes mellitus (T2DM) and colorectal...
Life, Vol. 10, Pages 215: Case Report: Identification of a Novel Variant (m.8909T>C) of Human Mitochondrial ATP6 Gene and Its Functional Consequences on Yeast ATP Synthase Life doi: 10.3390/life10090215 Authors: Qiuju Ding Róża Kucharczyk Weiwei Zhao Alain Dautant Shutian Xu Katarzyna Niedzwiecka Xin Su Marie-France Giraud Kewin Gombeau Mingchao Zhang Honglang Xie Caihong Zeng Marine Bouhier Jean-Paul di Rago Zhihong Liu Déborah Tribouillard-Tanvier...
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Medicina, Vol. 56, Pages 486: Exertional Heat Illness Preparedness Strategies: Environmental Monitoring Policies in United States High Schools Medicina doi: 10.3390/medicina56100486 Authors: Samantha E. Scarneo-Miller Luke N. Belval Susan W. Yeargin Yuri Hosokawa Zachary Y. Kerr Douglas J. Casa Background and objectives: Environmental monitoring allows for an analysis of the ambient conditions affecting a physically active person’s ability to thermoregulate and...
Medicina, Vol. 56, Pages 485: Novel Splice Site Mutation in the PROS1 Gene in a Polish Patient with Venous Thromboembolism: c.602-2delA, Splice Acceptor Site of Exon 7 Medicina doi: 10.3390/medicina56090485 Authors: Magdalena Mrożek Ewa Wypasek Martine Alhenc-Gelas Daniel P. Potaczek Anetta Undas We identified a novel splice site mutation of the PROS1 gene in a Polish family with protein S (PS) deficiency and explored the molecular pathogenesis of this previously undescribed...
Medicina, Vol. 56, Pages 483: Effects of Chewing Exerciser on the Recovery of Masticatory Function Recovery after Orthognathic Surgery: A Single-Center Randomized Clinical Trial, a Preliminary Study Medicina doi: 10.3390/medicina56090483 Authors: Hoon Joo Yang Ik Jae Kwon Akram Abdo Almansoori Yoojung Son Bongju Kim Soung-Min Kim Jong-Ho Lee Background and Objectives: The aim of this study was to evaluate the effects of the chewing exerciser (CE) on the functional recovery...
Medicina, Vol. 56, Pages 484: Complement Properdin Regulates the Metabolo-Inflammatory Response to a High Fat Diet Medicina doi: 10.3390/medicina56090484 Authors: Rόisín C. Thomas Ramiar Kheder Hasanain Alaridhee Naomi Martin Cordula M. Stover Background and objectives: Overnutrition leads to a metabolic and inflammatory response that includes the activation of Complement. Properdin is the only amplifier of complement activation and increases the provision of complement activation...
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Medicines, Vol. 7, Pages 59: Composition and Antibacterial Activity of the Essential Oil from Pimenta dioica (L.) Merr. from Guatemala Medicines doi: 10.3390/medicines7100059 Authors: Max Samuel Mérida-Reyes Manuel Alejandro Muñoz-Wug Bessie Evelyn Oliva-Hernández Isabel Cristina Gaitán-Fernández Daniel Luiz Reis Simas Antonio Jorge Ribeiro da Silva Juan Francisco Pérez-Sabino Background: Pimenta dioica is a native tree of Central America, Southern Mexico, and the Caribbean...
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Membranes, Vol. 10, Pages 249: Effect of Pretreatment on Hydraulic Performance of the Integrated Membrane Process for Concentrating Nutrient in Biogas Digestate from Swine Manure Membranes doi: 10.3390/membranes10100249 Authors: Yuanhang Zhan Fubin Yin Caide Yue Jun Zhu Zhiping Zhu Mengyuan Zou Hongmin Dong Nanofiltration (NF) or reverse osmosis (RO) process has been widely applied for concentrating nutrient in biogas digestate. However, efficient pretreatment is key...
Membranes, Vol. 10, Pages 248: Ceramic Microfiltration Membranes in Wastewater Treatment: Filtration Behavior, Fouling and Prevention Membranes doi: 10.3390/membranes10090248 Authors: Mohammed Wali Hakami Abdullah Alkhudhiri Sirhan Al-Batty Myrto-Panagiota Zacharof Jon Maddy Nidal Hilal Nowadays, integrated microfiltration (MF) membrane systems treatment is becoming widely popular due to its feasibility, process reliability, commercial availability, modularity, relative...
Membranes, Vol. 10, Pages 247: Simultaneous Quantification of Protein Binding Kinetics in Whole Cells with Surface Plasmon Resonance Imaging and Edge Deformation Tracking Membranes doi: 10.3390/membranes10090247 Authors: Wenwen Jing Ashley Hunt Nongjian Tao Fenni Zhang Shaopeng Wang Most drugs work by binding to receptors on the cell surface. Quantification of binding kinetics between drug and membrane protein is an essential step in drug discovery. Current methods for measuring...
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Metabolites, Vol. 10, Pages 379: Evaluation of Sample Preparation Methods for Inter‑Laboratory Metabolomics Investigation of Streptomyces lividans TK24 Metabolites doi: 10.3390/metabo10090379 Authors: Howbeer Muhamadali Kenneth Simoens Yun Xu Bart Nicolai Kristel Bernaerts Royston Goodacre In the past two decades, metabolomics has proved to be a valuable tool with many potential applications in different areas of science. However, there are still some challenges that need...
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Microorganisms, Vol. 8, Pages 1455: Three New Reports of Trichoderma in Algeria: T. atrobrunneum, (South) T. longibrachiatum (South), and T. afroharzianum (Northwest) Microorganisms doi: 10.3390/microorganisms8101455 Authors: Sadika Haouhach Noureddine Karkachi Bouchra Oguiba Abouamama Sidaoui Isabel Chamorro Mebrouk Kihal Enrique Monte The genus Trichoderma (Hypocreaceae, Ascomycota) consists of globally distributed fungi. In Algeria, few studies have explored the...
Microorganisms, Vol. 8, Pages 1454: Influence of Culture Conditions and Medium Compositions on the Production of Bacteriocin-Like Inhibitory Substances by Lactococcus lactis Gh1 Microorganisms doi: 10.3390/microorganisms8101454 Authors: Roslina Jawan Sahar Abbasiliasi Joo Shun Tan Shuhaimi Mustafa Murni Halim Arbakariya B. Ariff Antibacterial peptides or bacteriocins produced by many strains of lactic acid bacteria have been used as food preservatives for many years without...
Microorganisms, Vol. 8, Pages 1451: Syngas as Electron Donor for Sulfate and Thiosulfate Reducing Haloalkaliphilic Microorganisms in a Gas-Lift Bioreactor Microorganisms doi: 10.3390/microorganisms8091451 Authors: Caroline M. Plugge João A. B. Sousa Stephan Christel Mark Dopson Martijn F. M. Bijmans Alfons J. M. Stams Martijn Diender Biodesulfurization processes remove toxic and corrosive hydrogen sulfide from gas streams (e.g., natural gas, biogas, or syngas). To improve...
Microorganisms, Vol. 8, Pages 1452: Chlorine Disinfection of Legionella spp., L. pneumophila, and Acanthamoeba under Warm Water Premise Plumbing Conditions Microorganisms doi: 10.3390/microorganisms8091452 Authors: Rebekah L. Martin Kara Harrison Caitlin R. Proctor Amanda Martin Krista Williams Amy Pruden Marc A. Edwards Premise plumbing conditions can contribute to low chlorine or chloramine disinfectant residuals and reactions that encourage opportunistic pathogen...
Microorganisms, Vol. 8, Pages 1450: Multicenter Comparative Study of Six Cryptosporidium parvum DNA Extraction Protocols Including Mechanical Pretreatment from Stool Samples Microorganisms doi: 10.3390/microorganisms8091450 Authors: Nicolas Valeix Damien Costa Louise Basmaciyan Stéphane Valot Anne Vincent Romy Razakandrainibe Florence Robert-Gangneux Céline Nourrisson Bruno Pereira Emilie Fréalle Philippe Poirier Loic Favennec Frederic Dalle Background:...
Microorganisms, Vol. 8, Pages 1453: Enhancing the Rice Seedlings Growth Promotion Abilities of Azoarcus sp. CIB by Heterologous Expression of ACC Deaminase to Improve Performance of Plants Exposed to Cadmium Stress Microorganisms doi: 10.3390/microorganisms8091453 Authors: Helga Fernández-Llamosas Juan Ibero Sofie Thijs Valeria Imperato Jaco Vangronsveld Eduardo Díaz Manuel Carmona Environmental pollutants can generate stress in plants causing increased ethylene production...
Microorganisms, Vol. 8, Pages 1449: Population Dynamics between Erwinia amylovora, Pantoea agglomerans and Bacteriophages: Exploiting Synergy and Competition to Improve Phage Cocktail Efficacy Microorganisms doi: 10.3390/microorganisms8091449 Authors: Steven Gayder Michael Parcey Darlene Nesbitt Alan J. Castle Antonet M. Svircev Bacteriophages are viruses capable of recognizing with high specificity, propagating inside of, and destroying their bacterial hosts. The phage lytic...
Microorganisms, Vol. 8, Pages 1448: Francisella tularensis Subspecies holarctica and Tularemia in Germany Microorganisms doi: 10.3390/microorganisms8091448 Authors: Sandra Appelt Mirko Faber Kristin Köppen Daniela Jacob Roland Grunow Klaus Heuner Tularemia is a zoonotic disease caused by Francisella tularensis a small, pleomorphic, facultative intracellular bacterium. In Europe, infections in animals and humans are caused mainly by Francisella tularensis subspecies holarctica....
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Molecules, Vol. 25, Pages 4360: Hair Growth Activity of Three Plants of the Polynesian Cosmetopoeia and Their Regulatory Effect on Dermal Papilla Cells Molecules doi: 10.3390/molecules25194360 Authors: Kristelle Hughes Raimana Ho Stéphane Greff Edith Filaire Edwige Ranouille Claire Chazaud Gaëtan Herbette Jean-François Butaud Jean-Yves Berthon Phila Raharivelomanana Hair loss is becoming increasingly prevalent as dietary and living habits change. The search...
Molecules, Vol. 25, Pages 4361: Neoglycosylated Collagen: Effect on Neuroblastoma F-11 Cell Lines Molecules doi: 10.3390/molecules25194361 Authors: Antonella Sgambato Valentina Pastori Laura Russo Simone Vesentini Marzia Lecchi Laura Cipolla The regeneration of the nervous system is a challenging task. Currently, regenerative medicine approaches that exploit nature-inspired cues are being studied and hold great promise. The possibility to use protein-based matrices functionalized...
Molecules, Vol. 25, Pages 4358: Homology Modeling and Optimized Expression of Truncated IK Protein, tIK, as an Anti-Inflammatory Peptide Molecules doi: 10.3390/molecules25194358 Authors: Yuyoung Song Minseon Kim Yongae Kim Rheumatoid arthritis, caused by abnormalities in the autoimmune system, affects about 1% of the population. Rheumatoid arthritis does not yet have a proper treatment, and current treatment has various side effects. Therefore, there is a need for a therapeutic...
Molecules, Vol. 25, Pages 4359: Pyrroloquinoline Quinone Inhibits Rotenone-Induced Microglia Inflammation by Enhancing Autophagy Molecules doi: 10.3390/molecules25194359 Authors: Qi Zhang Jing Zhou Mi Shen Hui Xu Shu Yu Qiong Cheng Fei Ding Neuroinflammation is a feature common to neurodegenerative diseases, such as Parkinson’s disease (PD), which might be responsive to therapeutic intervention. Rotenone has been widely used to establish PD models by inducing...
Molecules, Vol. 25, Pages 4357: Genome-Based Insights into the Production of Carotenoids by Antarctic Bacteria, Planococcus sp. ANT_H30 and Rhodococcus sp. ANT_H53B Molecules doi: 10.3390/molecules25194357 Authors: Michal Styczynski Agata Rogowska Katarzyna Gieczewska Maciej Garstka Anna Szakiel Lukasz Dziewit Antarctic regions are characterized by low temperatures and strong UV radiation. This harsh environment is inhabited by psychrophilic and psychrotolerant organisms,...
Molecules, Vol. 25, Pages 4356: The Effect of Modified Porcine Surfactant Alone or in Combination with Polymyxin B on Lung Homeostasis in LPS-Challenged and Mechanically Ventilated Adult Rats Molecules doi: 10.3390/molecules25194356 Authors: Maros Kolomaznik Jana Kopincova Zuzana Nova Juliana Topercerova Ivan Zila Pavol Mikolka Petra Kosutova Katarina Matasova Henrieta Skovierova Marian Grendar Daniela Mokra Andrea Calkovska The study aimed to prove the...
Molecules, Vol. 25, Pages 4355: Synthesis of Hydrotalcites from Waste Steel Slag with [Bmim]OH Intercalated for the Transesterification of Glycerol Carbonate Molecules doi: 10.3390/molecules25194355 Authors: Guanhao Liu Jingyi Yang Xinru Xu Ca-Mg-Al hydrotalcites were prepared by coprecipitation from Type S95 steel slag of Shanghai Baosteel Group as supports of ionic liquid in this paper. Five basic ionic liquids [Bmim][CH3COO], [Bmim][HCOO], [Bmim]OH, [Bmim]Br and ChOH were prepared...
Molecules, Vol. 25, Pages 4353: A Two-Layer SVM Ensemble-Classifier to Predict Interface Residue Pairs of Protein Trimers Molecules doi: 10.3390/molecules25194353 Authors: Yanfen Lyu Xinqi Gong Study of interface residue pairs is important for understanding the interactions between monomers inside a trimer protein–protein complex. We developed a two-layer support vector machine (SVM) ensemble-classifier that considers physicochemical and geometric properties of amino acids...
Molecules, Vol. 25, Pages 4354: In Vitro Digestion and Fermentation by Human Fecal Microbiota of Polysaccharides from Flaxseed Molecules doi: 10.3390/molecules25194354 Authors: Xin Zhou Zhao Zhang Fenghong Huang Chen Yang Qingde Huang The digestion of flaxseed polysaccharides (FSP) in simulated saliva, gastric and small intestine conditions was assessed, as well as in vitro fermentation of FSP by human gut microbiota. FSP was not degraded in the simulated digestive systems...
Molecules, Vol. 25, Pages 4352: Inhibitory Activity of Quercetin 3-O-Arabinofuranoside and 2-Oxopomolic Acid Derived from Malus domestica on Soluble Epoxide Hydrolase Molecules doi: 10.3390/molecules25184352 Authors: In Sook Cho Jang Hoon Kim Yunjia Lin Xiang Dong Su Jong Seong Kang Seo Young Yang Young Ho Kim Flavonoids and triterpenoids were revealed to be the potential inhibitors on soluble epoxide hydrolase (sEH). The aim of this study is to reveal sEH inhibitors...
Molecules, Vol. 25, Pages 4351: Oxazolochlorins 21. Most Efficient Access to meso-Tetraphenyl- and meso-Tetrakis(pentafluorophenyl)porpholactones, and Their Zinc(II) and Platinum(II) Complexes Molecules doi: 10.3390/molecules25184351 Authors: Damaris Thuita Dinusha Damunupola Christian Brückner meso-Phenyl- and meso-pentafluorophenyl-porpholactones, their metal complexes, as well as porphyrinoids directly derived from them are useful in a number of technical and biomedical applications,...
Molecules, Vol. 25, Pages 4350: Comprehensive Evaluation of Metal Pollution in Urban Soils of a Post-Industrial City—a Case of Łódź, Poland Molecules doi: 10.3390/molecules25184350 Authors: Kinga Wieczorek Anna Turek Małgorzata Szczesio Wojciech M. Wolf The pollution of urban soils by metals is a global problem. Prolonged exposure of habitants who are in contact with metals retained in soil poses a health risk. This particularly applies to industrialized cities with developed...
Molecules, Vol. 25, Pages 4349: Volatile Profile Characterization of Croatian Commercial Sparkling Wines Molecules doi: 10.3390/molecules25184349 Authors: Ana-Marija Jagatić Korenika Darko Preiner Ivana Tomaz Ana Jeromel Commercial sparkling wine production represents a relatively low but important part of the Croatian wine production, especially in the Zagreb county. This study presents the results of volatile aroma compounds profile and organic acid composition of commercial...
Molecules, Vol. 25, Pages 4345: Comparison of the Partial Structure and Antioxidant Activity of Polysaccharides from Two Species of Chinese Truffles Molecules doi: 10.3390/molecules25184345 Authors: Xiaolin Li Zhongkai Zhu Lei Ye Zongjing Kang Xiaoping Zhang Yue Huang Bo Zhang Yuanfeng Zou Truffles are world-renowned premium commodities. Due to their unique aroma and rarity, the price of truffles has always been very high. In this study, Diethylaminoethyl anion exchange...
Molecules, Vol. 25, Pages 4347: Development of an Optimized MALDI-TOF-MS Method for High-Throughput Identification of High-Molecular-Weight Glutenin Subunits in Wheat Molecules doi: 10.3390/molecules25184347 Authors: You-Ran Jang Kyoungwon Cho Se Won Kim Susan B. Altenbach Sun-Hyung Lim Jae-Ryeong Sim Jong-Yeol Lee Because high-molecular-weight glutenin subunits (HMW-GS) are important contributors to wheat end-use quality, there is a need for high-throughput identification...
Molecules, Vol. 25, Pages 4348: Thymol Encapsulated into HP-β-Cyclodextrin as an Alternative to Synthetic Fungicides to Induce Lemon Resistance Against Sour Rot Decay Molecules doi: 10.3390/molecules25184348 Authors: Vicente Serna-Escolano María Serrano Daniel Valero María Isabel Rodríguez-López José Antonio Gabaldón Salvador Castillo Juan Miguel Valverde Pedro Javier Zapata Fabián Guillén Domingo Martínez-Romero Consumers demand the use of eco-friendly fungicides...
Molecules, Vol. 25, Pages 4346: Structure and Performance of Benzoxazine Composites for Space Radiation Shielding Molecules doi: 10.3390/molecules25184346 Authors: Scott Winroth Chris Scott Hatsuo Ishida Innovative multifunctional materials that combine structural functionality with other spacecraft subsystem functions have been identified as a key enabling technology for future deep space missions. In this work, we report the structure and performance of multifunctional polymer...
Molecules, Vol. 25, Pages 4344: Biocatalytic Potential of Native Basidiomycetes from Colombia for Flavour/Aroma Production Molecules doi: 10.3390/molecules25184344 Authors: David A. Jaramillo María J. Méndez Gabriela Vargas Elena E. Stashenko Aída-M. Vasco-Palacios Andrés Ceballos Nelson H. Caicedo Aromas and flavours can be produced from fungi by either de novo synthesis or biotransformation processes. Herein, the biocatalytic potential of seven basidiomycete species...
Molecules, Vol. 25, Pages 4343: The Lipidome Fingerprint of Longevity Molecules doi: 10.3390/molecules25184343 Authors: Mariona Jové Natàlia Mota-Martorell Irene Pradas José Daniel Galo-Licona Meritxell Martín-Gari Èlia Obis Joaquim Sol Reinald Pamplona Lipids were determinants in the appearance and evolution of life. Recent studies disclose the existence of a link between lipids and animal longevity. Findings from both comparative studies and genetics and nutritional...
Molecules, Vol. 25, Pages 4340: Urinary Resveratrol Metabolites Output: Differential Associations with Cardiometabolic Markers and Liver Enzymes in House-Dwelling Subjects Featuring Metabolic Syndrome Molecules doi: 10.3390/molecules25184340 Authors: Vanessa Bullón-Vela Itziar Abete Maria Angeles Zulet Yifan Xu Miguel A. Martínez-González Carmen Sayón-Orea Miguel Ruiz-Canela Estefanía Toledo Vicente Martín Sánchez Ramon Estruch Rosa María Lamuela-Raventós Enrique...
Molecules, Vol. 25, Pages 4342: Design, Synthesis, In Vitro and In Silico Studies of New Thiazolylhydrazine-Piperazine Derivatives as Selective MAO-A Inhibitors Molecules doi: 10.3390/molecules25184342 Authors: Begüm Nurpelin Sağlık Osman Cebeci Ulviye Acar Çevik Derya Osmaniye Serkan Levent Betül Kaya Çavuşoğlu Sinem Ilgın Yusuf Özkay Zafer Asım Kaplancıklı Monoamine oxidase (MAO) isoenzymes are very important drug targets among neurological disorders. Herein,...
Molecules, Vol. 25, Pages 4341: Novel Bis-Ammonium Salts of Pyridoxine: Synthesis and Antimicrobial Properties Molecules doi: 10.3390/molecules25184341 Authors: Nikita V. Shtyrlin Mikhail V. Pugachev Sergey V. Sapozhnikov Marsel R. Garipov Rusalia M. Vafina Denis Yu. Grishaev Roman S. Pavelyev Renata R. Kazakova Mariya N. Agafonova Alfiya G. Iksanova Svetlana A. Lisovskaya Marina I. Zeldi Elena S. Krylova Elena V. Nikitina Alina E. Sabirova Airat...
Molecules, Vol. 25, Pages 4338: Autophagy, One of the Main Steps in Periodontitis Pathogenesis and Evolution Molecules doi: 10.3390/molecules25184338 Authors: Maria Greabu Francesca Giampieri Marina Melescanu Imre Maria Mohora Alexandra Totan Silviu Mirel Pituru Ecaterina Ionescu Periodontitis represents a complex inflammatory disease that compromises the integrity of the tooth-supporting tissue through the interaction of specific periodontal pathogens and the host’s...
Molecules, Vol. 25, Pages 4339: Conformation of G-quadruplex Controlled by Click Reaction Molecules doi: 10.3390/molecules25184339 Authors: Chao-Da Xiao Zhi-Yong He Chuan-Xin Guo Xiang-Chun Shen Yan Xu G-quadruplexes are non-canonical four stranded secondary structures possessing great biological importance. Controlling G-quadruplex conformation for further regulating biological processes is both exciting and challenging. In this study, we described a method for regulating...
Molecules, Vol. 25, Pages 4336: Antioxidant Extracts of Three Russula Genus Species Express Diverse Biological Activity Molecules doi: 10.3390/molecules25184336 Authors: Marina Kostić Marija Ivanov Ângela Fernandes José Pinela Ricardo C. Calhelha Jasmina Glamočlija Lillian Barros Isabel C. F. R. Ferreira Marina Soković Ana Ćirić This study explored the biological properties of three wild growing Russula species (R. integra, R. rosea, R. nigricans) from Serbia....
Molecules, Vol. 25, Pages 4334: N-Benzyl Residues as the P1′ Substituents in Phosphorus-Containing Extended Transition State Analog Inhibitors of Metalloaminopeptidases Molecules doi: 10.3390/molecules25184334 Authors: Kamila Janiszewska Michał Talma Bartosz Oszywa Małgorzata Pawełczak Paweł Kafarski Artur Mucha Peptidyl enzyme inhibitors containing an internal aminomethylphosphinic bond system (P(O)(OH)-CH2-NH) can be termed extended transition state analogs by similarity...
Molecules, Vol. 25, Pages 4337: Sulphamoylated Estradiol Analogue Induces Reactive Oxygen Species Generation to Exert Its Antiproliferative Activity in Breast Cancer Cell Lines Molecules doi: 10.3390/molecules25184337 Authors: Maphuti T. Lebelo Anna M. Joubert Michelle H. Visagie 2-Methoxyestradiol (2ME), a 17β-estradiol metabolite, exerts anticancer properties in vitro and in vivo. To address 2ME’s low bioavailability, research led to the in silico design of...
Molecules, Vol. 25, Pages 4335: Isolation and FTIR-ATR and 1H NMR Characterization of Alginates from the Main Alginophyte Species of the Atlantic Coast of Morocco Molecules doi: 10.3390/molecules25184335 Authors: Zahira Belattmania Soukaina Kaidi Samir El Atouani Chaimaa Katif Fouad Bentiss Charafeddine Jama Abdeltif Reani Brahim Sabour Vitor Vasconcelos Alginates are widely used as gelling agents in textile print pastes, medical industries, impression material...
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Nanomaterials, Vol. 10, Pages 1895: Metal Organic Framework Derived MnO2-Carbon Nanotubes for Efficient Oxygen Reduction Reaction and Arsenic Removal from Contaminated Water Nanomaterials doi: 10.3390/nano10091895 Authors: Vadahanambi Sridhar Inwon Lee Kwang Hyo Jung Hyun Park Even though manganese oxides are attractive materials for batteries, super-capacitors and electro-catalysts for oxygen reduction reactions, in most practical applications MnO2 needs to be hybridized with...
Nanomaterials, Vol. 10, Pages 1894: Ferritin Nanocage: A Versatile Nanocarrier Utilized in the Field of Food, Nutrition, and Medicine Nanomaterials doi: 10.3390/nano10091894 Authors: Chenxi Zhang Xiaorong Zhang Guanghua Zhao Compared with other nanocarriers such as liposomes, mesoporous silica, and cyclodextrin, ferritin as a typical protein nanocage has received considerable attention in the field of food, nutrition, and medicine owing to its inherent cavity size, excellent water...
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Nutrients, Vol. 12, Pages 2902: An Exploratory Analysis of Changes in Mental Wellbeing Following Curcumin and Fish Oil Supplementation in Middle-Aged and Older Adults Nutrients doi: 10.3390/nu12102902 Authors: Julia C. Kuszewski Peter R. C. Howe Rachel H. X. Wong Curcumin has previously been shown to enhance mood in non-depressed older adults. However, observed benefits were limited to short-term supplementation (4 weeks). In a 16 week randomized, double-blind, placebo-controlled,...
Nutrients, Vol. 12, Pages 2903: Association of Serum Fatty Acids at Admission with the Age of Onset of Intracerebral Hemorrhage Nutrients doi: 10.3390/nu12102903 Authors: Takahisa Mori Kazuhiro Yoshioka Yuhei Tanno Shigen Kasakura Dietary triglycerides influence the serum concentrations of fatty acids (FA) and their weight percentages (wt%), which might be associated with the age of onset of intracerebral hemorrhage (ICH). We investigated the correlation between serum FA levels...
Nutrients, Vol. 12, Pages 2901: Physiologic Effects of Exogenous Dextrose in Murine Klebsiella pneumoniae Sepsis Vary by Route of Provision Nutrients doi: 10.3390/nu12102901 Authors: Byron Chuan Lanping Guo Bryce Cooper Sagar Rawal Teresa Gallego-Martin Yingze Zhang Bryan J. McVerry Christopher P. O’Donnell Faraaz Ali Shah Sepsis is characterized by a dysregulated immune response to infection. Nutrition is important in the care of septic patients, but the effects...
Nutrients, Vol. 12, Pages 2900: Urine Untargeted Metabolomic Profiling Is Associated with the Dietary Pattern of Successful Aging among Malaysian Elderly Nutrients doi: 10.3390/nu12102900 Authors: Nik Nur Izzati Nik Mohd Fakhruddin Suzana Shahar Intan Safinar Ismail Amalina Ahmad Azam Nor Fadilah Rajab Food intake biomarkers (FIBs) can reflect the intake of specific foods or dietary patterns (DP). DP for successful aging (SA) has been widely studied. However, the relationship...
Nutrients, Vol. 12, Pages 2899: Extended Reality Technologies in Nutrition Education and Behavior: Comprehensive Scoping Review and Future Directions Nutrients doi: 10.3390/nu12092899 Authors: Jared T. McGuirt Natalie K. Cooke Marissa Burgermaster Basheerah Enahora Grace Huebner Yu Meng Gina Tripicchio Omari Dyson Virginia C. Stage Siew Sun Wong The use of Extended Reality (XR) (i.e. Virtual and Augmented Reality) for nutrition education and behavior change...
Nutrients, Vol. 12, Pages 2898: KiwiC for Vitality: Results of a Randomized Placebo-Controlled Trial Testing the Effects of Kiwifruit or Vitamin C Tablets on Vitality in Adults with Low Vitamin C Levels Nutrients doi: 10.3390/nu12092898 Authors: Tamlin S. Conner Benjamin D. Fletcher Juliet M. Pullar Emma Spencer Louise A. Mainvil Margreet C. M. Vissers Consumption of vitamin C-rich fruit and vegetables has been associated with greater feelings of vitality. However, these...
Nutrients, Vol. 12, Pages 2896: Micronutrient Deficiencies in Laparoscopic Sleeve Gastrectomy Nutrients doi: 10.3390/nu12092896 Authors: Omar Jamil Raquel Gonzalez-Heredia Pablo Quadri Chandra Hassan Mario Masrur Reed Berger Karen Bernstein Lisa Sanchez-Johnsen The purpose of this study was to conduct a literature review to examine micronutrient deficiencies in laparoscopic sleeve gastrectomy. We conducted a literature review using PubMed and Cochrane databases to...
Nutrients, Vol. 12, Pages 2897: Omega-3 Fatty Acid and Iron Supplementation Alone, but Not in Combination, Lower Inflammation and Anemia of Infection in Mycobacterium tuberculosis-Infected Mice Nutrients doi: 10.3390/nu12092897 Authors: Arista Nienaber Jeannine Baumgartner Robin C Dolman Mumin Ozturk Lizelle Zandberg Frank E.A Hayford Frank Brombacher Renee Blaauw Suraj P Parihar Cornelius M Smuts Linda Malan Progressive inflammation and anemia are common...
Nutrients, Vol. 12, Pages 2895: Interplay of Enzyme Therapy and Dietary Management of Murine Homocystinuria Nutrients doi: 10.3390/nu12092895 Authors: Insun Park Erez M. Bublil Frank Glavin Tomas Majtan Albeit effective, methionine/protein restriction in the management of classical homocystinuria (HCU) is suboptimal and hard to follow. To address unmet need, we developed an enzyme therapy (OT-58), which effectively corrected disease symptoms in various mouse models of HCU in...
Nutrients, Vol. 12, Pages 2893: Dietary Polyphenols and Human Health Nutrients doi: 10.3390/nu12092893 Authors: Anna Tresserra-Rimbau Plant-based foods are the main source of phytochemicals, including polyphenols, a large family of compounds with highly diverse chemical structures [...]
Nutrients, Vol. 12, Pages 2894: Promoting Healthy Eating among Young People—A Review of the Evidence of the Impact of School-Based Interventions Nutrients doi: 10.3390/nu12092894 Authors: Abina Chaudhary František Sudzina Bent Egberg Mikkelsen Intro: Globally, the prevalence of overweight and obesity is increasing among children and younger adults and is associated with unhealthy dietary habits and lack of physical activity. School food is increasingly brought forward as a policy...
Nutrients, Vol. 12, Pages 2890: Impact of a Scalable, Multi-Campus “Foodprint” Seminar on College Students’ Dietary Intake and Dietary Carbon Footprint Nutrients doi: 10.3390/nu12092890 Authors: Hannah Malan Ghislaine Amsler Challamel Dara Silverstein Charlie Hoffs Edward Spang Sara A. Pace Benji Lee Reade Malagueño Christopher D. Gardner May C. Wang Wendelin Slusser Jennifer A. Jay Background: Dietary patterns affect both human health and environmental...
Nutrients, Vol. 12, Pages 2891: Associations between Genotype–Diet Interactions and Weight Loss—A Systematic Review Nutrients doi: 10.3390/nu12092891 Authors: Sandra Bayer Vincent Winkler Hans Hauner Christina Holzapfel Studies on the interactions between single nucleotide polymorphisms (SNPs) and macronutrient consumption on weight loss are rare and heterogeneous. This review aimed to conduct a systematic literature search to investigate genotype–diet interactions...
Nutrients, Vol. 12, Pages 2892: DGLA from the Microalga Lobosphaera Incsa P127 Modulates Inflammatory Response, Inhibits iNOS Expression and Alleviates NO Secretion in RAW264.7 Murine Macrophages Nutrients doi: 10.3390/nu12092892 Authors: Ekaterina Novichkova Katya Chumin Noy Eretz-Kdosha Sammy Boussiba Jacob Gopas Guy Cohen Inna Khozin-Goldberg Microalgae have been considered as a renewable source of nutritional, cosmetic and pharmaceutical compounds. The ability to...
Nutrients, Vol. 12, Pages 2888: Pre-Sleep Low Glycemic Index Modified Starch Does Not Improve Next-Morning Fuel Selection or Running Performance in Male and Female Endurance Athletes Nutrients doi: 10.3390/nu12092888 Authors: Monique D. Dudar Emilie D. Bode Karly R. Fishkin Rochelle A. Brown Madeleine M. Carre Noa R. Mills Michael J. Ormsbee Stephen J. Ives To determine the effects of pre-sleep supplementation with a novel low glycemic index (LGI) carbohydrate (CHO)...
Nutrients, Vol. 12, Pages 2889: Effect of Dietary Magnesium Content on Intestinal Microbiota of Rats
Nutrients, Vol. 12, Pages 2889: Effect of Dietary Magnesium Content on Intestinal Microbiota of Rats Nutrients doi: 10.3390/nu12092889 Authors: Arantxa García-Legorreta Luis Alfonso Soriano-Pérez Aline Mariana Flores-Buendía Omar Noel Medina-Campos Lilia G. Noriega Omar Granados-Portillo Rafael Nambo-Venegas Armando R. Tovar Alfredo Mendoza-Vargas Diana Barrera-Oviedo José Pedraza-Chaverri Berenice Palacios-González Background: Magnesium is a mineral...
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Pathogens, Vol. 9, Pages 775: Orthohantaviruses, Emerging Zoonotic Pathogens Pathogens doi: 10.3390/pathogens9090775 Authors: Emmanuel Kabwe Yuriy Davidyuk Anton Shamsutdinov Ekaterina Garanina Ekaterina Martynova Kristina Kitaeva Moffat Malisheni Guzel Isaeva Tatiana Savitskaya Richard A. Urbanowicz Sergey Morzunov Cyprian Katongo Albert Rizvanov Svetlana Khaiboullina Orthohantaviruses give rise to the emerging infections such as of hemorrhagic...
Pathogens, Vol. 9, Pages 774: Transposon Insertion in the purL Gene Induces Biofilm Depletion in Escherichia coli ATCC 25922 Pathogens doi: 10.3390/pathogens9090774 Authors: Virginio Cepas Victoria Ballén Yaiza Gabasa Miriam Ramírez Yuly López Sara Mª Soto Current Escherichia coli antibiofilm treatments comprise a combination of antibiotics commonly used against planktonic cells, leading to treatment failure. A better understanding of the genes involved in biofilm formation...
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Pharmaceuticals, Vol. 13, Pages 264: Current Pharmacological Treatment Options for Central Serous Chorioretinopathy: A Review Pharmaceuticals doi: 10.3390/ph13100264 Authors: Massimo Nicolò Lorenzo Ferro Desideri Aldo Vagge Carlo Enrico Traverso Central serous chorioretinopathy (CSC) is a common cause of visual impairment in patients generally aged 20 to 60 and it is characterized by acute or chronic neurosensory detachments of the retina. Although CSC resolves spontaneously...
Pharmaceuticals, Vol. 13, Pages 263: Screening of Bacterial Quorum Sensing Inhibitors in a Vibrio fischeri LuxR-Based Synthetic Fluorescent E. coli Biosensor Pharmaceuticals doi: 10.3390/ph13090263 Authors: Xiaofei Qin Celina Vila-Sanjurjo Ratna Singh Bodo Philipp Francisco M. Goycoolea A library of 23 pure compounds of varying structural and chemical characteristics was screened for their quorum sensing (QS) inhibition activity using a synthetic fluorescent Escherichia coli...
Pharmaceuticals, Vol. 13, Pages 262: Fragaria viridis Fruit Metabolites: Variation of LC-MS Profile and Antioxidant Potential during Ripening and Storage Pharmaceuticals doi: 10.3390/ph13090262 Authors: Daniil N. Olennikov Aina G. Vasilieva Nadezhda K. Chirikova Fragaria viridis Weston or creamy strawberry is one of the less-known species of the Fragaria genus (Rosaceae family) with a wide distribution in Eurasia and is still in the shadow of more popular relatives F. ananassa...
Pharmaceuticals, Vol. 13, Pages 261: Vascular α1A Adrenergic Receptors as a Potential Therapeutic Target for IPAD in Alzheimer’s Disease Pharmaceuticals doi: 10.3390/ph13090261 Authors: Miles Frost Abby Keable Dan Baseley Amber Sealy Diana Andreea Zbarcea Maureen Gatherer Ho Ming Yuen Matt MacGregor Sharp Roy O. Weller Johannes Attems Colin Smith Paul R. Chiarot Roxana O. Carare Drainage of interstitial fluid from the brain occurs via the intramural...
Pharmaceuticals, Vol. 13, Pages 260: Adenosine Signaling in Autoimmune Disorders Pharmaceuticals doi: 10.3390/ph13090260 Authors: Giulia Magni Stefania Ceruti The molecular components of the purinergic system (i.e., receptors, metabolizing enzymes and membrane transporters) are widely expressed in the cells of the immune system. Additionally, high concentrations of adenosine are generated from the hydrolysis of ATP in any “danger” condition, when oxygen and energy...
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Pharmaceutics, Vol. 12, Pages 904: Conformal Coating of Powder by Initiated Chemical Vapor Deposition on Vibrating Substrate Pharmaceutics doi: 10.3390/pharmaceutics12090904 Authors: Katrin Unger Anna Maria Coclite Encapsulation of pharmaceutical powders within thin functional polymer films is a powerful and versatile method to modify drug release properties. Conformal coating over the complete surface of the particle via chemical vapor deposition techniques is a challenging task...
Pharmaceutics, Vol. 12, Pages 902: Composite Hydrogel of Methacrylated Hyaluronic Acid and Fragmented Polycaprolactone Nanofiber for Osteogenic Differentiation of Adipose-Derived Stem Cells Pharmaceutics doi: 10.3390/pharmaceutics12090902 Authors: Madhumita Patel Won-Gun Koh Composite hydrogels with electrospun nanofibers (NFs) have recently been used to mimic the native extracellular matrix. In this study, composite hydrogels of methacrylated hyaluronic acid containing fragmented...
Pharmaceutics, Vol. 12, Pages 903: PLGA Based Drug Carrier and Pharmaceutical Applications: The Most Recent Advances Pharmaceutics doi: 10.3390/pharmaceutics12090903 Authors: Joana Angélica Loureiro Maria Carmo Pereira Poly(lactic-co-glycolic acid) (PLGA) is one of the most successful polymers that has been used to produce medicines, such as drug carriers (DC) [...]
Pharmaceutics, Vol. 12, Pages 901: Development of 3D Printed Drug-Eluting Scaffolds for Preventing Piercing Infection Pharmaceutics doi: 10.3390/pharmaceutics12090901 Authors: Emad Naseri Christopher Cartmell Matthew Saab Russell G. Kerr Ali Ahmadi Herein, novel drug-eluting, bio-absorbable scaffold intended to cover piercing studs is introduced. This “biopierce” will stay in human tissue following piercing, and will slowly release an antimicrobial agent...
Pharmaceutics, Vol. 12, Pages 899: Photostability Testing of a Third-Generation Retinoid—Tazarotene in the Presence of UV Absorbers Pharmaceutics doi: 10.3390/pharmaceutics12090899 Authors: Agata Kryczyk-Poprawa István Zupkó Péter Bérdi Paweł Żmudzki Justyna Popiół Bożena Muszyńska Włodzimierz Opoka Exposure of a drug to UV irradiation could affect its physicochemical properties. Hence, photostability testing is essential for topically administered drugs. Tazarotene,...
Pharmaceutics, Vol. 12, Pages 900: Optimisation of Mycobacterium bovis BCG Fermentation and Storage Survival Pharmaceutics doi: 10.3390/pharmaceutics12090900 Authors: Jordan Pascoe Charlotte L. Hendon-Dunn Colin P.D. Birch Gareth A. Williams Mark A. Chambers Joanna Bacon Mycobacterium bovis Bacillus Calmette–Guérin (M. bovis BCG) was generated over a century ago for protection against Mycobacterium tuberculosis (Mtb) and is one the oldest vaccines...
Pharmaceutics, Vol. 12, Pages 898: Frequency of CYP3A5 Genetic Polymorphisms and Tacrolimus Pharmacokinetics in Pediatric Liver Transplantation Pharmaceutics doi: 10.3390/pharmaceutics12090898 Authors: Jefferson Antonio Buendía Esteban Halac Andrea Bosaleh María T. Garcia de Davila Oscar Imvertasa Guillermo Bramuglia The evidence available in the pediatric population is limited for making clinical decisions regarding the optimization of tacrolimus (TAC) in pharmacotherapy....
Pharmaceutics, Vol. 12, Pages 897: Liposomes Co-Encapsulating Cisplatin/Mifepristone Improve the Effect on Cervical Cancer: In Vitro and In Vivo Assessment Pharmaceutics doi: 10.3390/pharmaceutics12090897 Authors: Fabricio Ledezma-Gallegos Rafael Jurado Roser Mir Luis Alberto Medina Laura Mondragon-Fuentes Patricia Garcia-Lopez Cervical cancer is usually diagnosed in the later stages despite many campaigns for early detection and continues to be a major public health problem....
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Plants, Vol. 9, Pages 1250: Phenolic Compounds Content and Genetic Diversity at Population Level across the Natural Distribution Range of Bearberry (Arctostaphylos uva-ursi, Ericaceae) in the Iberian Peninsula Plants doi: 10.3390/plants9091250 Authors: Esther Asensio Daniel Vitales Iván Pérez Laia Peralba Juan Viruel Celia Montaner Joan Vallès Teresa Garnatje Ester Sales Bearberry (Arctostaphylos uva-ursi) is a medicinal plant traditionally employed for the treatment...
Plants, Vol. 9, Pages 1249: Cytotoxicity, Phytochemical, Antiparasitic Screening, and Antioxidant Activities of Mucuna pruriens (Fabaceae) Plants doi: 10.3390/plants9091249 Authors: Mahboob Adekilekun Jimoh Oladayo Amed Idris Muhali Olaide Jimoh This study aimed at assessing the biological activities of Mucuna pruriens seeds using cytotoxicity, phytochemical, antiparasitic screening, and antioxidant assays. Mature fruits of M. pruriens were harvested from Fort Hare University’s...
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Proteomes, Vol. 8, Pages 26: Glycoproteomic Analysis Reveals Aberrant Expression of Complement C9 and Fibronectin in the Plasma of Patients with Colorectal Cancer Proteomes doi: 10.3390/proteomes8030026 Authors: Juthamard Chantaraamporn Voraratt Champattanachai Amnart Khongmanee Chris Verathamjamras Naiyarat Prasongsook Kanokwan Mingkwan Virat Luevisadpibul Somchai Chutipongtanate Jisnuson Svasti Colorectal cancer (CRC) is a major cause of cancer mortality. Currently...
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Social Sciences, Vol. 9, Pages 166: Democracy, Biodiversity and More than Human Justice Imperatives: Institutional Responses to Crisis Social Sciences doi: 10.3390/socsci9090166 Authors: Tracey Skillington In terms of a human responsibility for the wrongful expulsion of non-human nature from natural habitats through wildfires, global warming, the over-exploitation of lands, seas and biological life, humanity is forced to revisit some fundamental issues of late with regard to the ongoing...
Social Sciences, Vol. 9, Pages 165: The “New Normal” and “Pandemic Populism”: The COVID-19 Crisis and Anti-Hygienic Mobilisation of the Far-Right Social Sciences doi: 10.3390/socsci9090165 Authors: Ulrike M. Vieten The paper is meant as a timely intervention into current debates on the impact of the global pandemic on the rise of global far-right populism and contributes to scholarly thinking about the normalisation of the global far-right. While approaching the tension between national...
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Stats, Vol. 3, Pages 412-426: On the Use of the Cumulative Distribution Function for Large-Scale Tolerance Analyses Applied to Electric Machine Design Stats doi: 10.3390/stats3030026 Authors: Edmund Marth Gerd Bramerdorfer In the field of electrical machine design, excellent performance for multiple objectives, like efficiency or torque density, can be reached by using contemporary optimization techniques. Unfortunately, highly optimized designs are prone to be rather sensitive regarding...
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Toxics, Vol. 8, Pages 77: Spatial Distribution and Ecological Risks of the Potentially-Toxic Elements in the Surface Sediments of Lake Bosten, China Toxics doi: 10.3390/toxics8030077 Authors: Long Ma Jilili Abuduwaili Wen Liu Aiming at the pollution and ecological hazards of the lake sediments of Bosten Lake, once China’s largest inland lake, the spatial distribution and influencing factors of the potentially-toxic elements in its surface sediments were studied with the...
Toxics, Vol. 8, Pages 76: In Vitro and In Vivo Evaluation of the Toxic Effects of Dodecylguanidine Hydrochloride Toxics doi: 10.3390/toxics8030076 Authors: Yeon-Mi Lim Haewon Kim Seong Kwang Lim Jean Yoo Ji-Young Lee Ig-Chun Eom Byung-Il Yoon Pilje Kim Seung-Do Yu Ilseob Shim The toxicity profiles of the widely used guanidine-based chemicals have not been fully elucidated. Herein, we evaluated the in vitro and in vivo toxicity of eight guanidine-based chemicals,...
Toxics, Vol. 8, Pages 75: Environmental Health and Ecological Risk Assessment of Soil Heavy Metal Pollution in the Coastal Cities of Estuarine Bay—A Case Study of Hangzhou Bay, China Toxics doi: 10.3390/toxics8030075 Authors: Rongxi Li Yuan Yuan Chengwei Li Wei Sun Meng Yang Xiangrong Wang Shanghai is the major city on the north shore of Hangzhou Bay, and the administrative regions adjacent to Hangzhou Bay are the Jinshan district, Fengxian district, and Pudong new area...
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Toxins, Vol. 12, Pages 608: The Parotoid Gland Secretion from Peruvian Toad Rhinella horribilis (Wiegmann, 1833): Chemical Composition and Effect on the Proliferation and Migration of Lung Cancer Cells Toxins doi: 10.3390/toxins12090608 Authors: Guillermo Schmeda-Hirschmann Jean Paulo de Andrade Marilú Roxana Soto-Vasquez Paul Alan Arkin Alvarado-García Charlotte Palominos Sebastián Fuentes-Retamal Mathias Mellado Pablo Correa Félix A. Urra Since Rhinella sp....
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Vaccines, Vol. 8, Pages 556: Impact of COVID-19 on Immunization Services for Maternal and Infant Vaccines: Results of a Survey Conducted by Imprint—The Immunising Pregnant Women and Infants Network Vaccines doi: 10.3390/vaccines8030556 Authors: Anja Saso Helen Skirrow Beate Kampmann The COVID-19 pandemic response has caused disruption to healthcare services globally, including to routine immunizations. To understand immunization service interruptions specifically for maternal,...
Vaccines, Vol. 8, Pages 554: Inflammasome-Mediated Immunogenicity of Clinical and Experimental Vaccine Adjuvants Vaccines doi: 10.3390/vaccines8030554 Authors: Sören Reinke Aneesh Thakur Cillian Gartlan Jelena S. Bezbradica Anita Milicic In modern vaccines, adjuvants can be sophisticated immunological tools to promote robust and long-lasting protection against prevalent diseases. However, there is an urgent need to improve immunogenicity of vaccines in order to protect mankind...
Vaccines, Vol. 8, Pages 555: Advances in the Development of Anti-Haemonchus contortus Vaccines: Challenges, Opportunities, and Perspectives Vaccines doi: 10.3390/vaccines8030555 Authors: Muhammad Ehsan Rui-Si Hu Qin-Li Liang Jun-Ling Hou Xiaokai Song Ruofeng Yan Xing-Quan Zhu Xiangrui Li The gastrointestinal nematode parasite Haemonchus contortus (H. contortus) is a resident of tropical and subtropical regions worldwide that imposes significant production losses,...
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Veterinary Sciences, Vol. 7, Pages 142: Overt Infection with Chronic Bee Paralysis Virus (CBPV) in Two Honey Bee Colonies Veterinary Sciences doi: 10.3390/vetsci7030142 Authors: Julia Dittes Marc O. Schäfer Heike Aupperle-Lellbach Christoph K. W. Mülling Ilka U. Emmerich Chronic Bee Paralysis Virus (CBPV), a widespread honey bee RNA virus, causes massive worker bee losses, mostly in strong colonies. Two different syndromes, with paralysis, ataxia and flight incapacity on...
Veterinary Sciences, Vol. 7, Pages 141: Neutrophil-to-Lymphocyte Ratio (NLR) in Canine Inflammatory Bowel Disease (IBD) Veterinary Sciences doi: 10.3390/vetsci7030141 Authors: Elena Benvenuti Alessio Pierini Eleonora Gori Claudia Lucarelli George Lubas Veronica Marchetti Inflammatory bowel disease (IBD) is a multifactorial chronic inflammatory disorder leading to structural changes in the intestinal wall. In humans, the neutrophil-to-lymphocyte ratio (NLR) has been proposed...
Veterinary Sciences, Vol. 7, Pages 140: Identifying Sources of Potential Bias When Using Online Survey Data to Explore Horse Training, Management, and Behaviour: A Systematic Literature Review Veterinary Sciences doi: 10.3390/vetsci7030140 Authors: Kate Fenner Michelle Hyde Angela Crean Paul McGreevy Owner-reported behavioural observations form an essential part of the veterinarians’ diagnosis and treatment plan. The way we train and manage horses affects their behaviour...
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Viruses, Vol. 12, Pages 1059: Tick-Borne Flaviviruses Depress AKT Activity during Acute Infection by Modulating AKT1/2 Viruses doi: 10.3390/v12101059 Authors: Joshua M. Kirsch Luwanika Mlera Danielle K. Offerdahl Marthe VanSickle Marshall E. Bloom Tick-borne flaviviruses (TBFVs) are reemerging public health threats. To develop therapeutics against these pathogens, increased understanding of their interactions with the mammalian host is required. The PI3K-AKT pathway has been...
Viruses, Vol. 12, Pages 1055: The Epidemiological Signature of Pathogen Populations That Vary in the Relationship between Free-Living Parasite Survival and Virulence Viruses doi: 10.3390/v12091055 Authors: Lourdes M. Gomez Victor A. Meszaros Wendy C. Turner C. Brandon Ogbunugafor The relationship between parasite virulence and transmission is a pillar of evolutionary theory that has implications for public health. Part of this canon involves the idea that virulence and free-living...
Viruses, Vol. 12, Pages 1057: An Unconventional Flavivirus and Other RNA Viruses in the Sea Cucumber (Holothuroidea; Echinodermata) Virome Viruses doi: 10.3390/v12091057 Authors: Ian Hewson Mitchell R. Johnson Ian R. Tibbetts Sea cucumbers (Holothuroidea; Echinodermata) are ecologically significant constituents of benthic marine habitats. We surveilled RNA viruses inhabiting eight species (representing four families) of holothurian collected from four geographically distinct locations...
Viruses, Vol. 12, Pages 1058: Drug Repositioning: New Approaches and Future Prospects for Life-Debilitating Diseases and the COVID-19 Pandemic Outbreak Viruses doi: 10.3390/v12091058 Authors: Zheng Yao Low Isra Ahmad Farouk Sunil Kumar Lal Traditionally, drug discovery utilises a de novo design approach, which requires high cost and many years of drug development before it reaches the market. Novel drug development does not always account for orphan diseases, which have low demand...
Viruses, Vol. 12, Pages 1056: A Unique Relative of Rotifer Birnavirus Isolated from Australian Mosquitoes Viruses doi: 10.3390/v12091056 Authors: Caitlin A. O’Brien Cassandra L. Pegg Amanda S. Nouwens Helle Bielefeldt-Ohmann Bixing Huang David Warrilow Jessica J. Harrison John Haniotis Benjamin L. Schulz Devina Paramitha Agathe M. G. Colmant Natalee D. Newton Stephen L. Doggett Daniel Watterson Jody Hobson-Peters Roy A. Hall The family Birnaviridae...
Viruses, Vol. 12, Pages 1054: Identification of a Membrane Binding Peptide in the Envelope Protein of MHV Coronavirus Viruses doi: 10.3390/v12091054 Authors: Entedar A. J. Alsaadi Benjamin W. Neuman Ian M. Jones Coronaviruses (CoVs) are enveloped, positive sense, single strand RNA viruses that cause respiratory, intestinal and neurological diseases in mammals and birds. Following replication, CoVs assemble on intracellular membranes including the endoplasmic reticulum Golgi intermediate...
Viruses, Vol. 12, Pages 1053: Structural Biology of Influenza Hemagglutinin: An Amaranthine Adventure Viruses doi: 10.3390/v12091053 Authors: Nicholas C. Wu Ian A. Wilson Hemagglutinin (HA) glycoprotein is an important focus of influenza research due to its role in antigenic drift and shift, as well as its receptor binding and membrane fusion functions, which are indispensable for viral entry. Over the past four decades, X-ray crystallography has greatly facilitated our understanding...
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Water, Vol. 12, Pages 2653: Investigating the Status of Cadmium, Chromium and Lead in the Drinking Water Supply Chain to Ensure Drinking Water Quality in Malaysia Water doi: 10.3390/w12102653 Authors: Minhaz Farid Ahmed Mazlin Bin Mokhtar Lubna Alam Che Abd Rahim Mohamed Goh Choo Ta Prolonged persistence of toxic cadmium (Cd), chromium (Cr) and lead (Pb) in the aquatic environment are due to its nonbiodegradable characteristic. A few studies have reported higher concentrations...
Water, Vol. 12, Pages 2652: Climatic and Anthropogenic Impacts on Environmental Conditions and Phytoplankton Community in the Gulf of Trieste (Northern Adriatic Sea) Water doi: 10.3390/w12092652 Authors: Stefano Cozzi Marina Cabrini Martina Kralj Cinzia De Vittor Massimo Celio Michele Giani During the last century, human activities have exerted an increasing pressure on coastal ecosystems, primarily inducing their eutrophication, with a more recent partial mitigation...
Water, Vol. 12, Pages 2651: New Geomorphological and Historical Elements on Morpho-Evolutive Trends and Relative Sea-Level Changes of Naples Coast in the Last 6000 Years Water doi: 10.3390/w12092651 Authors: Gaia Mattei Pietro P. C. Aucelli Claudia Caporizzo Angela Rizzo Gerardo Pappone This research aims to present new data regarding the relative sea-level variations and related morpho-evolutive trends of Naples coast since the mid-Holocene, by interpreting several geomorphological...
Water, Vol. 12, Pages 2650: Lake Phytoplankton Assemblage Altered by Irregularly Shaped PLA Body Wash Microplastics but not by PS Calibration Beads Water doi: 10.3390/w12092650 Authors: Kiyoko Yokota Marissa Mehlrose Microplastics are an emerging environmental pollutant, whose global ubiquity is becoming increasingly evident. Conventional wastewater treatment does not completely remove them, and there are growing concerns about microplastics in source water and post-treatment drinking...
Water, Vol. 12, Pages 2649: An Interval Fuzzy, Double-Sided, Chance-Constrained Stochastic Programming Model for Planning the Ecological Service Value of Interconnected River Systems Water doi: 10.3390/w12092649 Authors: Luze Yang Weiyi Cong Chong Meng Baofeng Cai Miao Liu The western region of Jilin Province is an ecologically fragile area with scarce water resources. The effective allocation of the limited water resources in order to obtain a higher ecological service value...
Water, Vol. 12, Pages 2648: Mountain Lake Evaporation: A Comparative Study between Hourly Estimations Models and In Situ Measurements Water doi: 10.3390/w12092648 Authors: Andrés Pérez Octavio Lagos Mario Lillo-Saavedra Camilo Souto Jerónimo Paredes José Luis Arumí The quantification of evaporation is very important for water resource management, determination of water availability and environmental modeling. Evaporation (E) is a key component of the hydrological cycle,...
Water, Vol. 12, Pages 2646: Rainwater Harvesting Techniques to Face Water Scarcity in African Drylands: Hydrological Efficiency Assessment Water doi: 10.3390/w12092646 Authors: Paolo Tamagnone Luis Cea Elena Comino Maurizio Rosso The sub-Saharan climate is experiencing a marked increase in temperature and intensification of precipitation intensity and variability. Besides, longer dry spells are compromising the reliability of local agricultural practices. The present study provides...
Water, Vol. 12, Pages 2647: Modelling Pluvial Flooding in Urban Areas Coupling the Models Iber and SWMM Water doi: 10.3390/w12092647 Authors: Esteban Sañudo Luis Cea Jerónimo Puertas Dual urban drainage models allow users to simulate pluvial urban flooding by analysing the interaction between the sewer network (minor drainage system) and the overland flow (major drainage system). This work presents a free distribution dual drainage model linking the models Iber and Storm Water...
Water, Vol. 12, Pages 2644: The Influence of Grain Size Distribution on the Hydraulic Gradient for Initiating Backward Erosion Water doi: 10.3390/w12092644 Authors: Willem-Jan Dirkx Rens van Beek Marc Bierkens Backward erosion by piping is one of the processes that threaten the stability of river embankments in the Netherlands. During high river stages, groundwater flow velocities underneath the embankment increase as a result of the steepened hydraulic gradient. If a single outflow...
Water, Vol. 12, Pages 2645: Effect of Climate Change on a Monolithic Desulphurized Tailings Cover Water doi: 10.3390/w12092645 Authors: Rashid Bashir Fiaz Ahmad Ryley Beddoe A soil cover system can be viewed as a thin interface placed between the atmosphere and the underlying waste. Climate is a primary design variable in soil cover design; therefore, climate change poses a number of challenges to design, operation and long-term performance of covers. In this research climate change...
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