IJERPH, Vol. 17, Pages 6939: Impact of Job Insecurity on Psychological Well- and Ill-Being among High Performance Coaches International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17196939 Authors: Marte Bentzen Göran Kenttä Anne Richter Pierre-Nicolas Lemyre Background: The evaluative nature of high performance (HP) sport fosters performance expectations that can be associated with harsh scrutiny, criticism, and job insecurity. In this context, (HP)...
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IJERPH, Vol. 17, Pages 6938: Quality of Life of Cancer Patients Treated with Chemotherapy International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17196938 Authors: Anna Lewandowska Grzegorz Rudzki Tomasz Lewandowski Michał Próchnicki Sławomir Rudzki Barbara Laskowska Joanna Brudniak Background: Life-quality tests are the basis for assessing the condition of oncological patients. They allow for obtaining valuable information from the patients...
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IJERPH, Vol. 17, Pages 6937: An Introduction to Probabilistic Record Linkage with a Focus on Linkage Processing for WTC Registries International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186937 Authors: Jana Asher Dean Resnick Jennifer Brite Robert Brackbill James Cone Since its post-World War II inception, the science of record linkage has grown exponentially and is used across industrial, governmental, and academic agencies. The academic fields...
Tue Sep 22, 2020 03:00
IJERPH, Vol. 17, Pages 6936: Are Advanced Glycation End Products in Skin Associated with Vascular Dysfunction Markers? A Meta-Analysis International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186936 Authors: Alicia Saz-Lara Celia Álvarez-Bueno Vicente Martínez-Vizcaíno Blanca Notario-Pacheco Irene Sequí-Dominguez Iván Cavero-Redondo Evidence exists regarding the association between advanced glycation end products and different cardiovascular...
Tue Sep 22, 2020 03:00
IJERPH, Vol. 17, Pages 6933: Unveiling COVID-19 from CHEST X-Ray with Deep Learning: A Hurdles Race with Small Data International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186933 Authors: Enzo Tartaglione Carlo Alberto Barbano Claudio Berzovini Marco Calandri Marco Grangetto The possibility to use widespread and simple chest X-ray (CXR) imaging for early screening of COVID-19 patients is attracting much interest from both the clinical and the...
Tue Sep 22, 2020 03:00
IJERPH, Vol. 17, Pages 6934: Personal Music Players Use and Other Noise Hazards among Children 11 to 12 Years Old International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186934 Authors: Weronika Swierniak Elzbieta Gos Piotr Henryk Skarzynski Natalia Czajka Henryk Skarzynski Exposure to loud music—due to widespread personal music players (PMPs) and noisy leisure activities—are major risk factors for noise induced hearing loss...
Tue Sep 22, 2020 03:00
IJERPH, Vol. 17, Pages 6932: Thermal Sensation in Older People with and without Dementia Living in Residential Care: New Assessment Approaches to Thermal Comfort Using Infrared Thermography International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186932 Authors: Charmaine Childs Jennifer Elliott Khaled Khatab Susan Hampshaw Sally Fowler-Davis Jon R. Willmott Ali Ali The temperature of the indoor environment is important for health and wellbeing,...
Tue Sep 22, 2020 03:00
IJERPH, Vol. 17, Pages 6935: Effectiveness of SaBang-DolGi Walking Exercise Program on Physical and Mental Health of Menopausal Women International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186935 Authors: Noh Kim Kim Yi Objective: We investigated the effectiveness of a 12-week SaBang-DolGi walking exercise program on the physical and mental health of menopausal women and aimed to provide the basic data needed to develop health promotion programs...
Tue Sep 22, 2020 03:00
IJERPH, Vol. 17, Pages 6930: The Visible Behaviour of Drowning Persons: A Pilot Observational Study Using Analytic Software and a Nominal Group Technique International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186930 Authors: Aida Carballo-Fazanes Joost J.L.M. Bierens the International Expert Group to Study Drowning Behaviour the International Expert Group to Study Drowning Behaviour Although drowning is a common phenomenon, the behaviour of drowning...
Tue Sep 22, 2020 03:00
IJERPH, Vol. 17, Pages 6929: Exploring Volatile Organic Compound Exposure and Its Association with Wheezing in Children under 36 Months: A Cross-Sectional Study in South Lisbon, Portugal International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186929 Authors: Rodrigues dos Santos Gregório Castanheira Fernandes Air quality and other environmental factors are gaining importance in public health policies. Some volatile organic compounds (VOCs)...
Tue Sep 22, 2020 03:00
IJERPH, Vol. 17, Pages 6928: Gaelic4Girls—The Effectiveness of a 10-Week Multicomponent Community Sports-Based Physical Activity Intervention for 8 to 12-Year-Old Girls International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186928 Authors: Farmer Cahill O’Brien Girls are less active than boys throughout childhood and adolescence, with limited research focusing on female community sports-based programs. This study aims to assess the effectiveness...
Tue Sep 22, 2020 03:00
IJERPH, Vol. 17, Pages 6923: Correlation of Caries Prevalence, Oral Health Behavior and Sweets Nutritional Habits among 10 to 19-Year-Old Cluj-Napoca Romanian Adolescents International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186923 Authors: Cosmin Tudoroniu Monica Popa Simona Maria Iacob Anca Lucia Pop Bogdana Adriana Năsui Background and objectives: The primary oral disease during adolescence is dental caries. Less is known about the caries...
Tue Sep 22, 2020 03:00
IJERPH, Vol. 17, Pages 6926: A Review of Maternal Nutrition during Pregnancy and Impact on the Offspring through Development: Evidence from Animal Models of Over- and Undernutrition International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186926 Authors: John F. Odhiambo Christopher L. Pankey Adel B. Ghnenis Stephen P. Ford Similarities in offspring phenotype due to maternal under- or over-nutrition during gestation have been observed in studies...
Tue Sep 22, 2020 03:00
IJERPH, Vol. 17, Pages 6931: Effects of PM2.5 on Third Grade Students’ Proficiency in Math and English Language Arts International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186931 Authors: Mullen Grineski Collins Mendoza Fine particulate air pollution is harmful to children in myriad ways. While evidence is mounting that chronic exposures are associated with reduced academic proficiency, no research has examined the frequency of peak exposures....
Tue Sep 22, 2020 03:00
IJERPH, Vol. 17, Pages 6927: A Qualitative Study of a Mindfulness-Based Intervention in Educational Contexts in Chile: An Approach Based on Adolescents’ Voices International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186927 Authors: Álvaro I. Langer Sebastián Medeiros Nelson Valdés-Sánchez Rodrigo Brito Christoph Steinebach Cristian Cid-Parra Antonella Magni Mariane Krause The application of mindfulness-based interventions in school...
Tue Sep 22, 2020 03:00
IJERPH, Vol. 17, Pages 6924: Public Awareness and Behaviour in Great Britain in the Context of Sunlight Exposure and Vitamin D: Results from the First Large-Scale and Representative Survey International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186924 Authors: Burchell Rhodes Webb In recent years, UK public health messages about the risks of sunlight exposure (skin cancer) have been increasingly balanced by messages about its benefits (vitamin...
Tue Sep 22, 2020 03:00
IJERPH, Vol. 17, Pages 6925: Prevalence of Arterial Hypertension and Characteristics of Nocturnal Blood Pressure Profile of Asthma Patients According to Therapy and Severity of the Disease: The BADA Study International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186925 Authors: Domenico Di Raimondo Gaia Musiari Alida Benfante Salvatore Battaglia Giuliana Rizzo Antonino Tuttolomondo Nicola Scichilone Antonio Pinto Background: several studies...
Tue Sep 22, 2020 03:00
IJERPH, Vol. 17, Pages 6921: “My Friends Are at the Bottom of My Schedule”: A Qualitative Study on Social Health among Nursing Students during Clinical Placement International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186921 Authors: Tam Mao Cheong Van Clinical placement is an essential component for nursing students, allowing them to transfer professional knowledge into practice. The quality of life among nursing students and nurses was reviewed...
Tue Sep 22, 2020 03:00
IJERPH, Vol. 17, Pages 6922: Leaders’ Future Orientation and Public Health Investment Intention: A Moderated Mediation Model of Self-Efficacy and Perceived Social Support International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186922 Authors: Jianming Wang Tsung Piao Chou Chia-Pin Chen Xiangzhi Bu Prior studies have investigated the issue of public health and health policy from economic, environmental, and healthcare perspectives. Research on public...
Tue Sep 22, 2020 03:00
IJERPH, Vol. 17, Pages 6919: The Analysis of the Frequency of Leukoplakia in Reference of Tobacco Smoking among Northern Polish Population International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186919 Authors: Aida Kusiak Adrian Maj Dominika Cichońska Barbara Kochańska Aleksandra Cydejko Dariusz Świetlik Objective: The aim of the study was an updated analysis of the frequency of leukoplakia in reference to tobacco smoking among the northern...
Tue Sep 22, 2020 03:00
IJERPH, Vol. 17, Pages 6920: Radiological Outcomes of Bone-Level and Tissue-Level Dental Implants: Systematic Review International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186920 Authors: Saverio Cosola Simone Marconcini Michela Boccuzzi Giovanni Battista Menchini Fabris Ugo Covani Miguel Peñarrocha-Diago David Peñarrocha-Oltra Background: to assess the radiological marginal bone loss between bone-level or tissue-level dental implants...
Tue Sep 22, 2020 03:00
IJERPH, Vol. 17, Pages 6915: Assessing 3-D Spatial Extent of Near-Road Air Pollution around a Signalized Intersection Using Drone Monitoring and WRF-CFD Modeling International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186915 Authors: Seung-Hyeop Lee Kyung-Hwan Kwak In this study, we have assessed the three-dimensional (3-D) spatial extent of near-road air pollution around a signalized intersection in a densely populated area using collaborating methodologies...
Tue Sep 22, 2020 03:00
IJERPH, Vol. 17, Pages 6917: Association between Primary Healthcare and Medical Expenditures in a Context of Hospital-Oriented Healthcare System in China: A National Panel Dataset, 2012–2016 International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186917 Authors: Mengping Zhou Jingyi Liao Nan Hu Li Kuang Total health expenditure in China has grown considerably since a new round of health system reform was enacted in 2009. Researchers have shown...
Tue Sep 22, 2020 03:00
IJERPH, Vol. 17, Pages 6918: Impact of Individual Headache Types on the Work and Work Efficiency of Headache Sufferers International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186918 Authors: Svetlana Simić Tamara Rabi-Žikić José R. Villar José Luis Calvo-Rolle Dragan Simić Svetislav D. Simić Background: Headaches have not only medical but also great socioeconomic significance, therefore, it is necessary to evaluate the overall impact of headaches...
Tue Sep 22, 2020 03:00
IJERPH, Vol. 17, Pages 6916: Clinical Application of Mindfulness-Oriented Meditation: A Preliminary Study in Children with ADHD International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186916 Authors: Ornella Santonastaso Vittoria Zaccari Cristiano Crescentini Franco Fabbro Viviana Capurso Stefano Vicari Deny Menghini Mindfulness-oriented meditation (MOM) is a self-regulatory training used for attentional and behavioral problems. With its...
Tue Sep 22, 2020 03:00
IJMS, Vol. 21, Pages 6985: Bone Microenvironment and Osteosarcoma Metastasis International Journal of Molecular Sciences doi: 10.3390/ijms21196985 Authors: Chaofei Yang Ye Tian Fan Zhao Zhihao Chen Peihong Su Yu Li Airong Qian The bone microenvironment is an ideal fertile soil for both primary and secondary tumors to seed. The occurrence and development of osteosarcoma, as a primary bone tumor, is closely related to the bone microenvironment. Especially, the metastasis...
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IJMS, Vol. 21, Pages 6984: Two Alternative Splicing Variants of AtERF73/HRE1, HRE1α and HRE1β, Have Differential Transactivation Activities in Arabidopsis International Journal of Molecular Sciences doi: 10.3390/ijms21196984 Authors: Hye-Yeon Seok Jimin Ha Sun-Young Lee Hyoungjoon Bae Yong-Hwan Moon AtERF73/HRE1 is an AP2/ERF transcription factor in Arabidopsis and has two distinct alternative splicing variants, HRE1α and HRE1β. In this study, we examined...
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IJMS, Vol. 21, Pages 6983: What Role Does COA6 Play in Cytochrome C Oxidase Biogenesis: A Metallochaperone or Thiol Oxidoreductase, or Both? International Journal of Molecular Sciences doi: 10.3390/ijms21196983 Authors: Shadi Maghool Michael T. Ryan Megan J. Maher Complex IV (cytochrome c oxidase; COX) is the terminal complex of the mitochondrial electron transport chain. Copper is essential for COX assembly, activity, and stability, and is incorporated into the dinuclear CuA and...
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IJMS, Vol. 21, Pages 6986: Cognitive Training as a Potential Activator of Hippocampal Neurogenesis in the Rat Model of Sporadic Alzheimer’s Disease International Journal of Molecular Sciences doi: 10.3390/ijms21196986 Authors: Alena O. Burnyasheva Tatiana A. Kozlova Natalia A. Stefanova Nataliya G. Kolosova Ekaterina A. Rudnitskaya There is a growing body of evidence that interventions like cognitive training or exercises prior to the manifestation of Alzheimer’s...
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IJMS, Vol. 21, Pages 6982: Interleukin-1β Alters Hebbian Synaptic Plasticity in Multiple Sclerosis International Journal of Molecular Sciences doi: 10.3390/ijms21196982 Authors: Mario Stampanoni Bassi Fabio Buttari Carolina Gabri Nicoletti Francesco Mori Luana Gilio Ilaria Simonelli Nicla De Paolis Girolama Alessandra Marfia Roberto Furlan Annamaria Finardi Diego Centonze Ennio Iezzi In multiple sclerosis (MS), inflammation alters synaptic transmission...
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IJMS, Vol. 21, Pages 6981: Lipid Composition Affects the Efficiency in the Functional Reconstitution of the Cytochrome c Oxidase International Journal of Molecular Sciences doi: 10.3390/ijms21196981 Authors: Katharina Gloria Hugentobler Dorothea Heinrich Johan Berg Joachim Heberle Peter Brzezinski Ramona Schlesinger Stephan Block The transmembrane protein cytochrome c oxidase (CcO) is the terminal oxidase in the respiratory chain of many aerobic organisms and catalyzes...
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IJMS, Vol. 21, Pages 6980: Role of miRNA-mRNA Interaction in Neural Stem Cell Differentiation of Induced Pluripotent Stem Cells International Journal of Molecular Sciences doi: 10.3390/ijms21196980 Authors: Satish Kumar Joanne E. Curran Erica DeLeon Ana C. Leandro Tom E. Howard Donna M. Lehman Sarah Williams-Blangero David C. Glahn John Blangero miRNA regulates the expression of protein coding genes and plays a regulatory role in human development and disease....
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IJMS, Vol. 21, Pages 6979: Pediatric Tuberculosis: The Impact of “Omics” on Diagnostics Development International Journal of Molecular Sciences doi: 10.3390/ijms21196979 Authors: Shailja Jakhar Alexis A. Bitzer Loreen R. Stromberg Harshini Mukundan Tuberculosis (TB) is a major public health concern for all ages. However, the disease presents a larger challenge in pediatric populations, partially owing to the lack of reliable diagnostic standards for the early identification...
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IJMS, Vol. 21, Pages 6978: Growth Differentiation Factor 15 Ameliorates Anti-Glomerular Basement Membrane Glomerulonephritis in Mice International Journal of Molecular Sciences doi: 10.3390/ijms21196978 Authors: Foteini Moschovaki-Filippidou Stefanie Steiger Georg Lorenz Christoph Schmaderer Andrea Ribeiro Ekaterina von Rauchhaupt Clemens D. Cohen Hans-Joachim Anders Maja Lindenmeyer Maciej Lech Growth differentiation factor 15 (GDF15) is a member of the transforming...
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IJMS, Vol. 21, Pages 6976: How Severe Anaemia Might Influence the Risk of Invasive Bacterial Infections in African Children International Journal of Molecular Sciences doi: 10.3390/ijms21186976 Authors: Kelvin M. Abuga John Muthii Muriuki Thomas N. Williams Sarah H. Atkinson Severe anaemia and invasive bacterial infections are common causes of childhood sickness and death in sub-Saharan Africa. Accumulating evidence suggests that severely anaemic African children may have a...
Tue Sep 22, 2020 03:00
IJMS, Vol. 21, Pages 6977: How Kinesin-1 Utilize the Energy of Nucleotide: The Conformational Changes and Mechanochemical Coupling in the Unidirectional Motion of Kinesin-1 International Journal of Molecular Sciences doi: 10.3390/ijms21186977 Authors: Jingyu Qin Hui Zhang Yizhao Geng Qing Ji Kinesin-1 is a typical motile molecular motor and the founding member of the kinesin family. The most significant feature in the unidirectional motion of kinesin-1 is its processivity. To...
Tue Sep 22, 2020 03:00
IJMS, Vol. 21, Pages 6975: Non-Coding RNAs, a Novel Paradigm for the Management of Gastrointestinal Stromal Tumors International Journal of Molecular Sciences doi: 10.3390/ijms21186975 Authors: Azadeh Amirnasr Stefan Sleijfer Erik A.C. Wiemer Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal malignancies found in the gastrointestinal tract. At a molecular level, most GISTs are characterized by gain-of-function mutations in V-Kit Hardy–Zuckerman 4...
Tue Sep 22, 2020 03:00
IJMS, Vol. 21, Pages 6974: A Novel Cis-Acting RNA Structural Element Embedded in the Core Coding Region of the Hepatitis C Virus Genome Directs Internal Translation Initiation of the Overlapping Core+1 ORF International Journal of Molecular Sciences doi: 10.3390/ijms21186974 Authors: Niki Vassilaki Efseveia Frakolaki Katerina I. Kalliampakou Panagiotis Sakellariou Ioly Kotta-Loizou Ralf Bartenschlager Penelope Mavromara Hepatitis C virus (HCV) genome translation is...
Tue Sep 22, 2020 03:00
IJMS, Vol. 21, Pages 6973: The Role of the Nrf2 Signaling in Obesity and Insulin Resistance International Journal of Molecular Sciences doi: 10.3390/ijms21186973 Authors: Shiri Li Natsuki Eguchi Hien Lau Hirohito Ichii Obesity, a metabolic disorder characterized by excessive accumulation of adipose tissue, has globally become an increasingly prevalent disease. Extensive studies have been conducted to elucidate the underlying mechanism of the development of obesity. In particular,...
Tue Sep 22, 2020 03:00
IJMS, Vol. 21, Pages 6967: Double-Stranded RNA Binding Proteins in Serum Contribute to Systemic RNAi Across Phyla—Towards Finding the Missing Link in Achelata International Journal of Molecular Sciences doi: 10.3390/ijms21186967 Authors: Thomas M. Banks Tianfang Wang Quinn P. Fitzgibbon Gregory G. Smith Tomer Ventura RNA interference (RNAi) has become a widely utilized method for studying gene function, yet despite this many of the mechanisms surrounding RNAi remain elusive....
Tue Sep 22, 2020 03:00
IJMS, Vol. 21, Pages 6962: Chondroprotective Actions of Selective COX-2 Inhibitors In Vivo: A Systematic Review International Journal of Molecular Sciences doi: 10.3390/ijms21186962 Authors: Ufuk Tan Timur Marjolein M. J. Caron Ralph M. Jeuken Yvonne M. Bastiaansen-Jenniskens Tim J. M. Welting Lodewijk W. van Rhijn Gerjo J. V. M. van Osch Pieter J. Emans Knee osteoarthritis (OA) is a condition mainly characterized by cartilage degradation. Currently, no effective...
Tue Sep 22, 2020 03:00
IJMS, Vol. 21, Pages 6968: CD8 T Cell Score as a Prognostic Biomarker for Triple Negative Breast Cancer International Journal of Molecular Sciences doi: 10.3390/ijms21186968 Authors: Masanori Oshi Mariko Asaoka Yoshihisa Tokumaru Li Yan Ryusei Matsuyama Takashi Ishikawa Itaru Endo Kazuaki Takabe CD8 T cell is an essential component of tumor-infiltrating lymphocytes (TIL) and tumor immune microenvironment (TIME). Using the xCell CD8 T cell score of whole tumor gene...
Tue Sep 22, 2020 03:00
IJMS, Vol. 21, Pages 6964: Antimicrobial Peptides as New Combination Agents in Cancer Therapeutics: A Promising Protocol against HT-29 Tumoral Spheroids International Journal of Molecular Sciences doi: 10.3390/ijms21186964 Authors: Mina Raileanu Aurel Popescu Mihaela Bacalum Antimicrobial peptides are molecules synthetized by a large variety of organisms as an innate defense against pathogens. These natural compounds have been identified as promising alternatives to widely used...
Tue Sep 22, 2020 03:00
IJMS, Vol. 21, Pages 6972: Monitoring of the Surface Charge Density Changes of Human Glioblastoma Cell Membranes upon Cinnamic and Ferulic Acids Treatment International Journal of Molecular Sciences doi: 10.3390/ijms21186972 Authors: Monika Naumowicz Magdalena Kusaczuk Marcin Zając Miroslav Gál Joanna Kotyńska Cinnamic acid (CA) and ferulic acid (FA) are naturally occurring phenolic acids claimed to exert beneficial effects against disorders related to oxidative stress, including...
Tue Sep 22, 2020 03:00
IJMS, Vol. 21, Pages 6969: Title Clinical Evidence of Antidepressant Effects of Insulin and Anti-Hyperglycemic Agents and Implications for the Pathophysiology of Depression—A Literature Review International Journal of Molecular Sciences doi: 10.3390/ijms21186969 Authors: Young Sup Woo Hyun Kook Lim Sheng-Min Wang Won-Myong Bahk Close connections between depression and type 2 diabetes (T2DM) have been suggested by many epidemiological and experimental studies. Disturbances in...
Tue Sep 22, 2020 03:00
IJMS, Vol. 21, Pages 6970: Comparison of miRNA Expression Profiles between HIV-1 and HIV-2 Infected Monocyte-Derived Macrophages (MDMs) and Peripheral Blood Mononuclear Cells (PBMCs) International Journal of Molecular Sciences doi: 10.3390/ijms21186970 Authors: Santanu Biswas Emily Chen Mohan Haleyurgirisetty Sherwin Lee Indira Hewlett Krishnakumar Devadas During the progression of HIV-1 infection, macrophage tropic HIV-1 that use the CCR5 co-receptor undergoes a change...
Tue Sep 22, 2020 03:00
IJMS, Vol. 21, Pages 6959: The Interplay between Toxic and Essential Metals for Their Uptake and Translocation Is Likely Governed by DNA Methylation and Histone Deacetylation in Maize International Journal of Molecular Sciences doi: 10.3390/ijms21186959 Authors: Sarfraz Shafiq Asim Ali Yasar Sajjad Qudsia Zeb Muhammad Shahzad Abdul Rehman Khan Rashid Nazir Emilie Widemann The persistent nature of lead (Pb) and cadmium (Cd) in the environment severely affects plant...
Tue Sep 22, 2020 03:00
IJMS, Vol. 21, Pages 6965: Semaphorin4A-Plexin D1 Axis Induces Th2 and Th17 While Represses Th1 Skewing in an Autocrine Manner International Journal of Molecular Sciences doi: 10.3390/ijms21186965 Authors: Tiago Carvalheiro Carlos Rafael-Vidal Beatriz Malvar-Fernandez Ana P. Lopes Jose M. Pego-Reigosa Timothy R. D. J. Radstake Samuel Garcia Semaphorin (Sema)4A is a transmembrane glycoprotein that is elevated in several autoimmune diseases such as systemic sclerosis,...
Tue Sep 22, 2020 03:00
IJMS, Vol. 21, Pages 6971: 4-Acetylantroquinonol B Inhibits Osteoclastogenesis by Inhibiting the Autophagy Pathway in a Simulated Microgravity Model International Journal of Molecular Sciences doi: 10.3390/ijms21186971 Authors: Chia-Hsin Wu Ching-Huei Ou I-Chuan Yen Shih-Yu Lee Astronauts suffer from 1–2% bone loss per month during space missions. Targeting osteoclast differentiation has been regarded as a promising strategy to prevent osteoporosis in microgravity...
Tue Sep 22, 2020 03:00
IJMS, Vol. 21, Pages 6963: Sudachinoid- and Ichangensin-Type Limonoids from Citrus junos Downregulate Pro-Inflammatory Cytokines International Journal of Molecular Sciences doi: 10.3390/ijms21186963 Authors: Jihun Shin Hwa Young Song Mina Lee Limonoids, a dominant group of phytochemicals in the Rutaceae family, are known to exhibit several pharmacological activities. To identify natural products having efficacy against inflammatory bowel disease (IBD), we isolated 13 limonoids...
Tue Sep 22, 2020 03:00
IJMS, Vol. 21, Pages 6966: IL-21 in Homeostasis of Resident Memory and Exhausted CD8 T Cells during Persistent Infection International Journal of Molecular Sciences doi: 10.3390/ijms21186966 Authors: Heather M. Ren Aron E. Lukacher CD4 T cells guide the development of CD8 T cells into memory by elaborating mitogenic and differentiation factors and by licensing professional antigen-presenting cells. CD4 T cells also act to stave off CD8 T cell dysfunction during repetitive antigen...
Tue Sep 22, 2020 03:00
IJMS, Vol. 21, Pages 6960: Imaging Diagnostics and Pathology in SARS-CoV-2-Related Diseases International Journal of Molecular Sciences doi: 10.3390/ijms21186960 Authors: Manuel Scimeca Nicoletta Urbano Rita Bonfiglio Manuela Montanaro Elena Bonanno Orazio Schillaci Alessandro Mauriello In December 2019, physicians reported numerous patients showing pneumonia of unknown origin in the Chinese region of Wuhan. Following the spreading of the infection over the world, The...
Tue Sep 22, 2020 03:00
IJMS, Vol. 21, Pages 6958: Functioning of the Photosynthetic Apparatus in Response to Drought Stress in Oat × Maize Addition Lines International Journal of Molecular Sciences doi: 10.3390/ijms21186958 Authors: Katarzyna Juzoń Dominika Idziak-Helmcke Magdalena Rojek-Jelonek Tomasz Warzecha Marzena Warchoł Ilona Czyczyło-Mysza Kinga Dziurka Edyta Skrzypek The oat × maize chromosome addition (OMA) lines, as hybrids between C3 and C4 plants, can potentially...
Tue Sep 22, 2020 03:00
IJMS, Vol. 21, Pages 6961: Self-Assembly of Amphiphilic Compounds as a Versatile Tool for Construction of Nanoscale Drug Carriers International Journal of Molecular Sciences doi: 10.3390/ijms21186961 Authors: Ruslan Kashapov Gulnara Gaynanova Dinar Gabdrakhmanov Denis Kuznetsov Rais Pavlov Konstantin Petrov Lucia Zakharova Oleg Sinyashin This review focuses on synthetic and natural amphiphilic systems prepared from straight-chain and macrocyclic compounds capable...
Tue Sep 22, 2020 03:00
IJMS, Vol. 21, Pages 6956: Characterization of a Topically Testable Model of Burn Injury on Human Skin Explants International Journal of Molecular Sciences doi: 10.3390/ijms21186956 Authors: Olivia Gross-Amat Marine Guillen Damien Salmon Serge Nataf Céline Auxenfans Severe burn injuries remain a major health problem due to high rates of mortality, residual morbidity, and/or aesthetic damages. To find new therapies aimed at promoting a harmonious healing of skin burns, it...
Tue Sep 22, 2020 03:00
IJMS, Vol. 21, Pages 6957: HSPA1L Enhances Cancer Stem Cell-Like Properties by Activating IGF1Rβ and Regulating β-Catenin Transcription International Journal of Molecular Sciences doi: 10.3390/ijms21186957 Authors: Soo-Im Choi Jei-Ha Lee Rae-Kwon Kim Uhee Jung Yeon-Jee Kahm Eun-Wie Cho In-Gyu Kim Studies have shown that cancer stem cells (CSCs) are involved in resistance and metastasis of cancer; thus, therapies targeting CSCs have been proposed. Here, we report that...
Tue Sep 22, 2020 03:00
IJMS, Vol. 21, Pages 6948: Are Alterations in Skeletal Muscle Mitochondria a Cause or Consequence of Insulin Resistance? International Journal of Molecular Sciences doi: 10.3390/ijms21186948 Authors: Amanda J. Genders Graham P. Holloway David J. Bishop As a major site of glucose uptake following a meal, skeletal muscle has an important role in whole-body glucose metabolism. Evidence in humans and animal models of insulin resistance and type 2 diabetes suggests that alterations...
Tue Sep 22, 2020 03:00
IJMS, Vol. 21, Pages 6955: Ribosome Pausing at Inefficient Codons at the End of the Replicase Coding Region Is Important for Hepatitis C Virus Genome Replication International Journal of Molecular Sciences doi: 10.3390/ijms21186955 Authors: Gesche K. Gerresheim Carolin S. Hess Lyudmila A. Shalamova Markus Fricke Manja Marz Dmitri E. Andreev Ivan N. Shatsky Michael Niepmann Hepatitis C virus (HCV) infects liver cells and often causes chronic infection, also leading...
Tue Sep 22, 2020 03:00
IJMS, Vol. 21, Pages 6954: Phospholipase D1 and D2 Synergistically Regulate Thrombus Formation International Journal of Molecular Sciences doi: 10.3390/ijms21186954 Authors: Li-Ming Lien Wan-Jung Lu Ting-Yu Chen Tzu-Yin Lee Hsueh-Hsiao Wang Hsien-Yu Peng Ray-Jade Chen Kuan-Hung Lin Previously, we reported that phospholipase D1 (PLD1) and PLD2 inhibition by selective PLD1 and PLD2 inhibitors could prevent platelet aggregation in humans, but not in mice. Moreover,...
Tue Sep 22, 2020 03:00
IJMS, Vol. 21, Pages 6953: Blocking of the IL-33/ST2 Signaling Axis by a Single-Chain Antibody Variable Fragment (scFv) Specific to IL-33 with a Defined Epitope International Journal of Molecular Sciences doi: 10.3390/ijms21186953 Authors: Soo Bin Park Sun-Jick Kim Sang Woo Cho Cheol Yong Choi Sangho Lee Interleukin 33 (IL-33) is an IL-1 family cytokine that plays a central role in immune system by regulating and initiating inflammatory responses. The binding of IL-33 to...
Tue Sep 22, 2020 03:00
IJMS, Vol. 21, Pages 6949: New Factors Enhancing the Reactivity of Cysteines in Molten Globule-Like Structures International Journal of Molecular Sciences doi: 10.3390/ijms21186949 Authors: Giorgia Gambardella Giada Cattani Alessio Bocedi Giorgio Ricci Protein cysteines often play crucial functional and structural roles, so they are emerging targets to design covalent thiol ligands that are able to modulate enzyme or protein functions. Some of these residues, especially those...
Tue Sep 22, 2020 03:00
IJMS, Vol. 21, Pages 6952: A Safe and Multitasking Antimicrobial Decapeptide: The Road from De Novo Design to Structural and Functional Characterization International Journal of Molecular Sciences doi: 10.3390/ijms21186952 Authors: Bruna Agrillo Yolande T. R. Proroga Marta Gogliettino Marco Balestrieri Rosarita Tatè Luigi Nicolais Gianna Palmieri Antimicrobial peptides (AMPs) are excellent candidates to fight multi-resistant pathogens worldwide and are considered promising...
Tue Sep 22, 2020 03:00
IJMS, Vol. 21, Pages 6951: Progress on Understanding Transcriptional Regulation of Chloroplast Development in Fleshy Fruit International Journal of Molecular Sciences doi: 10.3390/ijms21186951 Authors: Ting Jia Yuting Cheng Imran Khan Xuan Zhao Tongyu Gu Xueyun Hu Edible fleshy fruits are important food sources in the human diet. Their yield and nutritional quality have long been considered as breeding targets for improvement. Various developing fleshy fruits with functional...
Tue Sep 22, 2020 03:00
IJMS, Vol. 21, Pages 6950: Immunohistochemistry and Mutation Analysis of SDHx Genes in Carotid Paragangliomas International Journal of Molecular Sciences doi: 10.3390/ijms21186950 Authors: Anastasiya V. Snezhkina Dmitry V. Kalinin Vladislav S. Pavlov Elena N. Lukyanova Alexander L. Golovyuk Maria S. Fedorova Elena A. Pudova Maria V. Savvateeva Oleg A. Stepanov Andrey A. Poloznikov Tatiana B. Demidova Nataliya V. Melnikova Alexey A. Dmitriev George S....
Tue Sep 22, 2020 03:00
IJMS, Vol. 21, Pages 6947: A Complete Cross Section Data Set for Electron Scattering by Pyridine: Modelling Electron Transport in the Energy Range 0–100 eV International Journal of Molecular Sciences doi: 10.3390/ijms21186947 Authors: Filipe Costa Ali Traoré-Dubuis Lidia Álvarez Ana I. Lozano Xueguang Ren Alexander Dorn Paulo Limão-Vieira Francisco Blanco Juan C. Oller Antonio Muñoz Adrián García-Abenza Jimena D. Gorfinkiel Alessandra S. Barbosa Marcio...
Tue Sep 22, 2020 03:00
IJMS, Vol. 21, Pages 6945: Investigation of Biofilms Formed on Steelmaking Slags in Marine Environments for Water Depuration International Journal of Molecular Sciences doi: 10.3390/ijms21186945 Authors: Akiko Ogawa Reiji Tanaka Nobumitsu Hirai Tatsuki Ochiai Ruu Ohashi Karin Fujimoto Yuka Akatsuka Masanori Suzuki Steelmaking slags are a promising resource as artificial seaweed beds for the reconstitution of marine environments. To grow seaweed well, the formation...
Tue Sep 22, 2020 03:00
IJMS, Vol. 21, Pages 6946: Proteomic and Transcriptomic Patterns during Lipid Remodeling in Nannochloropsis gaditana International Journal of Molecular Sciences doi: 10.3390/ijms21186946 Authors: Chris J. Hulatt Irina Smolina Adam Dowle Martina Kopp Ghana K. Vasanth Galice G. Hoarau René H. Wijffels Viswanath Kiron Nutrient limited conditions are common in natural phytoplankton communities and are often used to increase the yield of lipids from industrial microalgae...
Tue Sep 22, 2020 03:00
IJMS, Vol. 21, Pages 6912: Plant Elongator—Protein Complex of Diverse Activities Regulates Growth, Development, and Immune Responses International Journal of Molecular Sciences doi: 10.3390/ijms21186912 Authors: Magdalena Jarosz Mieke Van Lijsebettens Magdalena Woloszynska Contrary to the conserved Elongator composition in yeast, animals, and plants, molecular functions and catalytic activities of the complex remain controversial. Elongator was identified as a component of elongating...
Tue Sep 22, 2020 03:00
IJMS, Vol. 21, Pages 6944: Alternating Electric Fields Modify the Function of Human Osteoblasts Growing on and in the Surroundings of Titanium Electrodes International Journal of Molecular Sciences doi: 10.3390/ijms21186944 Authors: Franziska Sahm Josefin Ziebart Anika Jonitz-Heincke Doris Hansmann Thomas Dauben Rainer Bader Endogenous electric fields created in bone tissue as a response to mechanical loading are known to influence the activity and differentiation of bone...
Tue Sep 22, 2020 03:00
JCM, Vol. 9, Pages 3062: Alcohol Septal Ablation versus Septal Myectomy Treatment of Obstructive Hypertrophic Cardiomyopathy: A Systematic Review and Meta-Analysis Journal of Clinical Medicine doi: 10.3390/jcm9103062 Authors: Ibadete Bytyçi Stefano Nistri Stellan Mörner Michael Y. Henein Surgical myectomy (SM) and alcohol septal ablation (ASA) are two invasive therapies for symptomatic patients with hypertrophic obstructive cardiomyopathy (HOCM), despite medical therapy. This...
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JCM, Vol. 9, Pages 3061: Effect of Instrument Design and Technique on the Precision and Accuracy of Objective Refraction Measurement Journal of Clinical Medicine doi: 10.3390/jcm9103061 Authors: Alberto Domínguez-Vicent Loujain Al-Soboh Rune Brautaset Abinaya Priya Venkataraman Background: To evaluate the precision and accuracy of objective refraction measurement obtained with combinations of instrument design and technique. We also compared the performance of the instruments...
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JCM, Vol. 9, Pages 3059: Impact of Psychological Distress and Sleep Quality on Balance Confidence, Muscle Strength, and Functional Balance in Community-Dwelling Middle-Aged and Older People Journal of Clinical Medicine doi: 10.3390/jcm9093059 Authors: Fábrega-Cuadros Aibar-Almazán Martínez-Amat Hita-Contreras The objective was to evaluate the associations of psychological distress and sleep quality with balance confidence, muscle strength, and functional balance among community-dwelling...
Tue Sep 22, 2020 03:00
JCM, Vol. 9, Pages 3060: Phosphatidylethanol for Monitoring Alcohol Use in Liver Transplant Candidates: An Observational Study Journal of Clinical Medicine doi: 10.3390/jcm9093060 Authors: Barrio Gual Lligoña Teixidor Weinmann Yegles Wurst Liver transplantation remains an essential procedure for many patients suffering from alcoholic liver disease. Alcohol use monitoring remains paramount all through the stages of this complex process. Direct alcohol biomarkers,...
Tue Sep 22, 2020 03:00
JCM, Vol. 9, Pages 3057: Contributions of Major Cell Populations to Sjögren’s Syndrome Journal of Clinical Medicine doi: 10.3390/jcm9093057 Authors: Richard Witas Shivai Gupta Cuong Q. Nguyen Sjögren’s syndrome (SS) is a female dominated autoimmune disease characterized by lymphocytic infiltration into salivary and lacrimal glands and subsequent exocrine glandular dysfunction. SS also may exhibit a broad array of extraglandular manifestations including an elevated...
Tue Sep 22, 2020 03:00
JCM, Vol. 9, Pages 3058: Motor Control Stabilisation Exercise for Patients with Non-Specific Low Back Pain: A Prospective Meta-Analysis with Multilevel Meta-Regressions on Intervention Effects Journal of Clinical Medicine doi: 10.3390/jcm9093058 Authors: Daniel Niederer Tilman Engel Lutz Vogt Adamantios Arampatzis Winfried Banzer Heidrun Beck María Moreno Catalá Michael Brenner-Fliesser Claas Güthoff Thore Haag Alexander Hönning Ann-Christin Pfeifer Petra...
Tue Sep 22, 2020 03:00
JCM, Vol. 9, Pages 3056: Characterization of Fetal Thyroid Levels at Delivery among Appalachian Infants Journal of Clinical Medicine doi: 10.3390/jcm9093056 Authors: Madison N. Crank Jesse N. Cottrell Brenda L. Mitchell Monica A. Valentovic Thyroid disorders are a frequently encountered issue during pregnancy and a cause of maternal and fetal morbidity. In regions like Appalachia that are particularly susceptible to health disparities, descriptive studies are needed to assist...
Tue Sep 22, 2020 03:00
JCM, Vol. 9, Pages 3052: Quantitative Analysis of Somatostatin and Dopamine Receptors Gene Expression Levels in Non-functioning Pituitary Tumors and Association with Clinical and Molecular Aggressiveness Features Journal of Clinical Medicine doi: 10.3390/jcm9093052 Authors: Álvaro Flores-Martinez Eva Venegas-Moreno Elena Dios Pablo Remón-Ruiz Noelia Gros-Herguido M. Carmen Vázquez-Borrego Ainara Madrazo-Atutxa Miguel A. Japón Ariel Kaen Eugenio Cárdenas-Valdepeñas...
Tue Sep 22, 2020 03:00
JCM, Vol. 9, Pages 3054: Evaluation of an Amino Acid Mix on the Secretion of Gastrointestinal Peptides, Glucometabolic Homeostasis, and Appetite in Obese Adolescents Administered with a Fixed-Dose or ad Libitum Meal Journal of Clinical Medicine doi: 10.3390/jcm9093054 Authors: Antonello E. Rigamonti Sofia Tamini Sabrina Cicolini Alessandra De Col Diana Caroli Stefania Mai Eugenia Rondinelli Antonella Saezza Silvano G. Cella Alessandro Sartorio Proteins have...
Tue Sep 22, 2020 03:00
JCM, Vol. 9, Pages 3051: Syndecan-4 as a Marker of Endothelial Dysfunction in Patients with Resistant Hypertension Journal of Clinical Medicine doi: 10.3390/jcm9093051 Authors: Mark Lipphardt Hassan Dihazi Jens-Holger Maas Ann-Kathrin Schäfer Saskia I. Amlaz Brian B. Ratliff Michael J. Koziolek Manuel Wallbach (1) Background: Arterial hypertension (HTN) is one of the most relevant cardiovascular risk factors. Nowadays multiple pharmaceutical treatment options exist...
Tue Sep 22, 2020 03:00
JCM, Vol. 9, Pages 3053: Monomeric C-Reactive Protein Aggravates Secondary Degeneration after Intracerebral Haemorrhagic Stroke and May Function as a Sensor for Systemic Inflammation Journal of Clinical Medicine doi: 10.3390/jcm9093053 Authors: Mark Slevin Elisa Garcia-Lara E Bogdan Capitanescu Coral Sanfeliu Yasmin Zeinolabediny Raid AlBaradie Peter Olah Baoqiang Guo Daniel Pirici Mario Di Napoli Aurel Popa-Wagner Background: We previously identified increased...
Tue Sep 22, 2020 03:00
JCM, Vol. 9, Pages 3055: The Frequency of, and Factors Associated with Prolonged Hospitalization: A Multicentre Study in Victoria, Australia Journal of Clinical Medicine doi: 10.3390/jcm9093055 Authors: Richard Ofori-Asenso Danny Liew Johan Mårtensson Daryl Jones Background: Limited available evidence suggests that a small proportion of inpatients undergo prolonged hospitalization and use a disproportionate number of bed days. Understanding the factors contributing to prolonged...
Tue Sep 22, 2020 03:00
JFB, Vol. 11, Pages 67: Bio-Based Electrospun Fibers for Wound Healing Journal of Functional Biomaterials doi: 10.3390/jfb11030067 Authors: Azimi Maleki Zavagna De la Ossa Linari Lazzeri Danti Being designated to protect other tissues, skin is the first and largest human body organ to be injured and for this reason, it is accredited with a high capacity for self-repairing. However, in the case of profound lesions or large surface loss, the natural wound healing...
Tue Sep 22, 2020 03:00
JoF, Vol. 6, Pages 186: Decomposition of Organic Chemical Components in Wood by Tropical Xylaria Species Journal of Fungi doi: 10.3390/jof6040186 Authors: Takashi Osono The ability of Xylaria species obtained from tropical wood and leaf litter to cause a mass loss of lignin and carbohydrates in wood was examined in vitro with pure culture decomposition tests. The mass loss of wood of four tree species caused by nine Xylaria isolates ranged from 4.5% to 28.4% of the original wood mass....
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JoF, Vol. 6, Pages 185: Echinocandins as Biotechnological Tools for Treating Candida auris Infections Journal of Fungi doi: 10.3390/jof6030185 Authors: Elizabete de Souza Cândido Flávia Affonseca Marlon Henrique Cardoso Octavio Luiz Franco Candida auris has been reported in the past few years as an invasive fungal pathogen of high interest. Its recent emergence in healthcare-associated infections triggered the efforts of researchers worldwide, seeking additional alternatives...
Tue Sep 22, 2020 03:00
JoF, Vol. 6, Pages 184: Designed Antimicrobial Peptides Against Trauma-Related Cutaneous Invasive Fungal Wound Infections Journal of Fungi doi: 10.3390/jof6030184 Authors: Kathryn W. Woodburn Jesse M. Jaynes L. Edward Clemens Cutaneous invasive fungal wound infections after life-threatening dismounted complex blast injury (DCBI) and natural disasters complicate clinical care. These wounds often require aggressive repeated surgical debridement, can result in amputations and hemipelvectomies...
Tue Sep 22, 2020 03:00
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