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Τετάρτη 23 Σεπτεμβρίου 2020

 

Stromal categorization in early oral tongue cancer.
Related Articles Stromal categorization in early oral tongue cancer. Virchows Arch. 2020 Sep 21;: Authors: Almangush A, Bello IO, Heikkinen I, Hagström J, Haglund C, Kowalski LP, Nieminen P, Coletta RD, Mäkitie AA, Salo T, Leivo I Abstract Stromal categorization has been used to classify many epithelial cancer types. We assessed the desmoplastic reaction and compared its significance with other stromal characteristics in early (cT1-2N0)...
Head and Neck
Tue Sep 22, 2020 13:21
A Meta-Analysis of the Association Between the Voice Handicap Index and Objective Voice Analysis.
Related Articles A Meta-Analysis of the Association Between the Voice Handicap Index and Objective Voice Analysis. J Speech Lang Hear Res. 2020 Sep 21;:1-11 Authors: Zhao EE, Nguyen SA, Salvador CD, O'Rourke AK Abstract Purpose Dysphonia can be evaluated by both patient-reported quality of life instruments and objective acoustic and aerodynamic analyses. However, less is known about the association between the two metrics. The goal of this...
Head and Neck
Tue Sep 22, 2020 15:19
18F-FDG PET/CT in Osteoradionecrosis of the Hyoid.
Related Articles 18F-FDG PET/CT in Osteoradionecrosis of the Hyoid. Clin Nucl Med. 2020 Sep 15;: Authors: Antippa SH, Du L, Price N, Hsu CC Abstract Osteoradionecrosis (ORN) is a well-documented complication following radiation treatment for head and neck malignancy. Facial bones, mainly the mandible, laryngeal cartilage, and skull, are frequently involved sites for ORN. A rare site for ORN is the hyoid, with very limited cases described...
Head and Neck
Tue Sep 22, 2020 13:21
Pupil-Sparing Third Nerve Palsy and Papilledema Due to Granulomatosis With Polyangiitis.
Related Articles Pupil-Sparing Third Nerve Palsy and Papilledema Due to Granulomatosis With Polyangiitis. J Neuroophthalmol. 2020 Sep 11;: Authors: Vosoughi AR, Streutker CJ, Yang SP, Lee JM, Micieli JA PMID: 32956224 [PubMed - as supplied by publisher]
Head and Neck
Tue Sep 22, 2020 13:21
Outpatient Posttraumatic Auricle Reconstruction Under Local Anesthesia.
Related Articles Outpatient Posttraumatic Auricle Reconstruction Under Local Anesthesia. J Craniofac Surg. 2020 Sep 08;: Authors: Barbieri D, Familiari M, Indelicato P, Bussi M Abstract We described an outpatient auricle reconstruction in an elderly patient after an accidental facial trauma. The procedure was carried out under local anesthesia given patient's comorbidities and acetylsalicylic acid (ASA) therapy. The patient subsequently...
Head and Neck
Tue Sep 22, 2020 13:21
Transseptal Suturing With Turbinate Coblation in Nasal Septoturbinoplasty.
Related Articles Transseptal Suturing With Turbinate Coblation in Nasal Septoturbinoplasty. J Craniofac Surg. 2020 Sep 08;: Authors: Lee YC, Hsin LJ, Chang CC, Tsai YT, Fang TJ Abstract OBJECTIVE: Transseptal suture-assisted septoplasty and coblation are two techniques that can effectively treat septal deviation and inferior turbinate hypertrophy without the need for post-operative packing. In the existing literature, however, the early...
Head and Neck
Tue Sep 22, 2020 13:21
Columellar Wound Immediately After Open Rhinoseptoplasty Treated With Application of DuoDERM Extra Thin.
Related Articles Columellar Wound Immediately After Open Rhinoseptoplasty Treated With Application of DuoDERM Extra Thin. J Craniofac Surg. 2020 Sep 08;: Authors: In SM, An HG, Kim JY, Lee KI Abstract Most patients who undergo open rhinoseptoplasty do not develop any wound at the transcolumellar incision site. However, some patients require wound care immediately post-operation. Dressing is difficult to perform in the columellar region...
Head and Neck
Tue Sep 22, 2020 13:21
[Reducing the impact of COVID-19 on radiation oncology units of developing countries: A rapid review and expert consensus].
Related Articles [Reducing the impact of COVID-19 on radiation oncology units of developing countries: A rapid review and expert consensus]. Medwave. 2020 Sep 07;20(8):e8012 Authors: Montero-Oleas N, Puente-Vallejo R, León-Micheli B, Imbaquingo-Cabrera A, Silva M, Gamarra E, Álvarez-Rodas B, Segovia N, Aldaz-Roldan P, Nuñez-Silva C, Zurita-Vivero K, Carrión A, Molina-Jaramillo J, Rodríguez-Balarezo A, Betancourt Y, De Los Reyes L Abstract ...
Head and Neck
Tue Sep 22, 2020 13:21
Lessons learned from open laryngotracheal airway resection and primary anastomosis in high risk patients.
Related Articles Lessons learned from open laryngotracheal airway resection and primary anastomosis in high risk patients. PLoS One. 2020;15(9):e0238426 Authors: Dewan K, Berke GS, Chhetri DK Abstract OBJECTIVE: Laryngotracheal stenosis is one of the most difficult conditions treated by the Otolaryngologist. Open resection of stenosis with primary airway anastomosis is the definitive treatment for this condition. However, some patients...
Head and Neck
Tue Sep 22, 2020 13:21
Simultaneous maxillary and mandibular reconstruction with a single Osteocutaneous fibula free flap: A description of three cases.
Related Articles Simultaneous maxillary and mandibular reconstruction with a single Osteocutaneous fibula free flap: A description of three cases. Microsurgery. 2020 Sep 21;: Authors: Krane NA, Fagin A, Ghanem TA, Cannady SB, Petrisor D, Wax MK Abstract Large defects that comprise both the maxilla and mandible prove to be difficult reconstructive endeavors and commonly require two free tissue transfers. Three cases are presented to discuss...
Head and Neck
Tue Sep 22, 2020 13:21
Management of Zygomaticomaxillary Complex Fractures Utilizing Intraoperative 3-Dimensional Imaging: The ZYGOMAS Protocol.
Related Articles Management of Zygomaticomaxillary Complex Fractures Utilizing Intraoperative 3-Dimensional Imaging: The ZYGOMAS Protocol. J Oral Maxillofac Surg. 2020 Aug 27;: Authors: Cuddy K, Dierks EJ, Cheng A, Patel A, Amundson M, Bell RB Abstract PURPOSE: Utilization of technology to aid in the assessment, planning, and management of complex craniomaxillofacial injuries is increasingly common. Limited data exist regarding the implication...
Head and Neck
Tue Sep 22, 2020 15:19
Silencing circular RNA hsa_circ_009755 promotes growth and metastasis of oral squamous cell carcinoma.
Related Articles Silencing circular RNA hsa_circ_009755 promotes growth and metastasis of oral squamous cell carcinoma. Genomics. 2020 Sep 18;: Authors: Zhang B, Wang Z, Shen Y, Yang H Abstract OBJECTIVE: Oral squamous cell carcinoma (OSCC) is a common and rampant malignancy of the head and neck. However, its pathogenesis remains unclear. In this study, we have investigated the effects of circular RNA hsa_circ_009755 on proliferation, migration,...
Head and Neck
Tue Sep 22, 2020 15:19
Carotid blowout syndrome after reirradiation for head and neck malignancies: a comprehensive systematic review for a pragmatic multidisciplinary approach.
Related Articles Carotid blowout syndrome after reirradiation for head and neck malignancies: a comprehensive systematic review for a pragmatic multidisciplinary approach. Crit Rev Oncol Hematol. 2020 Aug 25;155:103088 Authors: Alterio D, Turturici I, Volpe S, Ferrari A, Russell-Edu SW, Vischioni B, Mardighian D, Preda L, Gandini S, Marvaso G, Augugliaro M, Durante S, Arculeo S, Patti F, Boccuzzi D, Casbarra A, Starzynska A, Santoni R, Jereczek-Fossa BA ...
Head and Neck
Tue Sep 22, 2020 15:19
Concurrent use of aspirin with osimertinib is associated with improved survival in advanced EGFR-mutant non-small cell lung cancer.
Related Articles Concurrent use of aspirin with osimertinib is associated with improved survival in advanced EGFR-mutant non-small cell lung cancer. Lung Cancer. 2020 Sep 09;149:33-40 Authors: Liu X, Hong L, Nilsson M, Hubert SM, Wu S, Rinsurongkawong W, Lewis J, Spelman A, Roth J, Swisher S, He Y, Jack Lee J, Fang B, Heymach JV, Zhang J, Le X Abstract BACKGROUND: Osimertinib is the treatment of choice for advanced EGFR-mutant non-small...
Head and Neck
Tue Sep 22, 2020 15:19
Role of periostin in ECRS.
Related Articles Role of periostin in ECRS. Eur Arch Otorhinolaryngol. 2020 Sep 21;: Authors: Yu L, Wang J, Liu K Abstract Periostin, an extracelluar matrix protein belonging to the fasciclin family, has been reported to play a key role in the process of Th2-inflammation disease. As eoshinophilic chronic rhinosinusitis has a higher incident rate, studies show that periostin has participated in the process of inflammation and remodeling. This...
http://link.springer.com/journal/405,European archives of oto-rhino-laryngology,The European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino
Tue Sep 22, 2020 13:23
The impact of liver transplant recipient and donor genetic variability on tacrolimus exposure and transplant outcome.
Related Articles The impact of liver transplant recipient and donor genetic variability on tacrolimus exposure and transplant outcome. Br J Clin Pharmacol. 2019 09;85(9):2170-2175 Authors: Coller JK, Ramachandran J, John L, Tuke J, Wigg A, Doogue M Abstract This study investigated the effect of recipient and donor genetic variability on dose-adjusted steady-state tacrolimus concentrations (Css ) and clinical outcomes 3 and 6 months after liver...
pubmed: frontiers immunology
Tue Sep 22, 2020 13:23
Peri-orbital surgical emphysema following endoscopic dacryocystorhinostomy.
Related Articles Peri-orbital surgical emphysema following endoscopic dacryocystorhinostomy. J Laryngol Otol. 2020 Sep 21;:1-3 Authors: Bladen JC, Siah WF, Tan P, Litwin AS, Ali S, Malhotra R Abstract BACKGROUND: Peri-orbital surgical emphysema is a rare complication that can occur after lacrimal surgery. It has only been described in isolated cases, following external dacryocystorhinostomy (n = 2) and Lester Jones tube insertion (n = 1). ...
The Journal of laryngology and otology http://goo.gl/Tl02xD
Tue Sep 22, 2020 13:26
Tripartite motif-containing 35 (TRIM35) is up-regulated in UUO-induced renal fibrosis animal model.
Related Articles Tripartite motif-containing 35 (TRIM35) is up-regulated in UUO-induced renal fibrosis animal model. Histol Histopathol. 2020 Sep 21;:18255 Authors: Chen Y, Ding Y, Wang LM Abstract Renal fibrosis has been recognized as a serious health threat in the world because of the high cost of treatment and poor prognosis. However, the molecular mechanism of renal fibrosis is still largely unknown. In this study, we aimed at illustrating...
Cellular and Molecular Biology
Tue Sep 22, 2020 13:30
Age-specific colorectal cancer incidence rate in the world.
Related Articles Age-specific colorectal cancer incidence rate in the world. Jpn J Clin Oncol. 2020 Sep 21;: Authors: Saito E, Hori M PMID: 32954417 [PubMed - as supplied by publisher]
pubmed: "jpn j clin oncol"[j...
Tue Sep 22, 2020 13:35
Artery of Percheron pseudoaneurysm.
Related Articles Artery of Percheron pseudoaneurysm. J Clin Neurosci. 2020 Sep 17;: Authors: Ikeda DS, Miller CA PMID: 32951951 [PubMed - as supplied by publisher]
J Clin Neurosci
Tue Sep 22, 2020 13:36
The PROCLIPI international registry of early-stage mycosis fungoides identifies substantial diagnostic delay in most patients.
Related Articles The PROCLIPI international registry of early-stage mycosis fungoides identifies substantial diagnostic delay in most patients. Br J Dermatol. 2019 08;181(2):350-357 Authors: Scarisbrick JJ, Quaglino P, Prince HM, Papadavid E, Hodak E, Bagot M, Servitje O, Berti E, Ortiz-Romero P, Stadler R, Patsatsi A, Knobler R, Guenova E, Child F, Whittaker S, Nikolaou V, Tomasini C, Amitay I, Prag Naveh H, Ram-Wolff C, Battistella M, Alberti-Violetti S, Stranzenbach...
Rare Cancers
Tue Sep 22, 2020 13:38
Rare Presentation of Herpes Virus Lesions in a Case of Acute Pre-B Lymphoblastic Leukemia
Related Articles Rare Presentation of Herpes Virus Lesions in a Case of Acute Pre-B Lymphoblastic Leukemia Turk J Haematol. 2020 Feb 20;37(1):75-76 Authors: Kaymaz E, Güzelküçük Z, Işık M, Yaralı N PMID: 30468433 [PubMed - indexed for MEDLINE]
Rare Cancers
Tue Sep 22, 2020 13:38
Neuroma (schwannoma). A rare pancreatic tumor.
Related Articles Neuroma (schwannoma). A rare pancreatic tumor. Pol Przegl Chir. 2019 Feb 07;92(1):48-51 Authors: Witkowski G, Kołos M, Nasierowska-Guttmejer A, Durlik M Abstract INTRODUCTION: Neuroma (Schwannoma in Latin) is an encapsulated, mesenchymal tumor arising from Schwann cells surrounded by nerves. Hence it can be located in any area in the body with passing peripheral nerves. The most common location is the head, neck, and extremities....
Rare Cancers
Tue Sep 22, 2020 13:38
The effect of oral contraceptive pill cessation on hepatocellular adenoma diameter: A retrospective cohort study.
Related Articles The effect of oral contraceptive pill cessation on hepatocellular adenoma diameter: A retrospective cohort study. Liver Int. 2019 05;39(5):905-913 Authors: Haring MPD, Gouw ASH, de Haas RJ, Cuperus FJC, de Jong KP, de Meijer VE Abstract BACKGROUND & AIMS: Hepatocellular adenomas (HCA) are rare, hormone-driven, benign liver tumours. HCA >50 mm are associated with haemorrhage and malignant transformation. Guidelines recommend...
Rare Cancers
Tue Sep 22, 2020 13:38
Clinical management of localized undifferentiated sinonasal carcinoma: our experience and review of the literature.
Related Articles Clinical management of localized undifferentiated sinonasal carcinoma: our experience and review of the literature. Anticancer Drugs. 2019 03;30(3):308-312 Authors: Perri F, Della Vittoria Scarpati G, Ionna F, Longo F, Montano M, Muto P, Ravo V, Giuliano M, Caponigro F Abstract Undifferentiated sinonasal carcinoma (SNUC) is defined as a small round blue cell tumor that is immunohistochemically distinct from other sinonasal...
Rare Cancers
Tue Sep 22, 2020 13:38
Intensity-modulated radiation therapy with simultaneous integrated boost for locally advanced breast cancer: a prospective study on toxicity and quality of life.
Related Articles Intensity-modulated radiation therapy with simultaneous integrated boost for locally advanced breast cancer: a prospective study on toxicity and quality of life. Sci Rep. 2019 02 26;9(1):2759 Authors: Pasquier D, Le Tinier F, Bennadji R, Jouin A, Horn S, Escande A, Tresch E, Chauvet MP, Mailliez A, Crop F, Mirabel X, Lartigau E Abstract Radiotherapy after breast conserving surgery and mastectomy with node positive disease...
Rare Cancers
Tue Sep 22, 2020 13:38
A rare cause of acute epigastric pain during late pregnancy.
Related Articles A rare cause of acute epigastric pain during late pregnancy. Liver Int. 2019 07;39(7):1372 Authors: Zhang YM, Luo YF, Liu GM PMID: 31033113 [PubMed - indexed for MEDLINE]
Rare Cancers
Tue Sep 22, 2020 13:38
Whole Genome Sequencing of Single Circulating Tumor Cells Isolated by Applying a Pulsed Laser to Cell-Capturing Microstructures.
Related Articles Whole Genome Sequencing of Single Circulating Tumor Cells Isolated by Applying a Pulsed Laser to Cell-Capturing Microstructures. Small. 2019 09;15(37):e1902607 Authors: Kim O, Lee D, Chungwon Lee A, Lee Y, Bae HJ, Lee HB, Kim RN, Han W, Kwon S Abstract Single cell analysis of heterogeneous circulating tumor cells (CTCs), by which the genomic profiles of rare single CTCs are connected to the clinical status of cancer patients,...
Rare Cancers
Tue Sep 22, 2020 13:38
Precise Size-Based Cell Separation via the Coupling of Inertial Microfluidics and Deterministic Lateral Displacement.
Related Articles Precise Size-Based Cell Separation via the Coupling of Inertial Microfluidics and Deterministic Lateral Displacement. Anal Chem. 2019 08 06;91(15):10328-10334 Authors: Xiang N, Wang J, Li Q, Han Y, Huang D, Ni Z Abstract We report here a novel two-stage i-DLD sorter through coupling inertial microfluidics with deterministic lateral displacement (DLD), allowing for precise, continuous, and size-based cell separation. The first...
Rare Cancers
Tue Sep 22, 2020 13:38
Impact of AAV2 and Hepatitis B Virus Integration Into Genome on Development of Hepatocellular Carcinoma in Patients with Prior Hepatitis B Virus Infection.
Related Articles Impact of AAV2 and Hepatitis B Virus Integration Into Genome on Development of Hepatocellular Carcinoma in Patients with Prior Hepatitis B Virus Infection. Clin Cancer Res. 2019 10 15;25(20):6217-6227 Authors: Tatsuno K, Midorikawa Y, Takayama T, Yamamoto S, Nagae G, Moriyama M, Nakagawa H, Koike K, Moriya K, Aburatani H Abstract PURPOSE: Hepatitis B viral (HBV) DNA is frequently integrated into the genomes of hepatocellular...
Rare Cancers
Tue Sep 22, 2020 13:38
Detection of a novel CBFB-MYH11 fusion transcript in acute myeloid leukemia M1 with inv(16)(p13q22).
Related Articles Detection of a novel CBFB-MYH11 fusion transcript in acute myeloid leukemia M1 with inv(16)(p13q22). Cancer Genet. 2020 02;241:72-76 Authors: Kurata K, Yamamoto K, Okazaki Y, Noguchi Y, Matsui K, Matsumoto H, Inui Y, Yakushijin K, Ito M, Nakamachi Y, Matsuoka H, Saegusa J, Minami H Abstract Acute myeloid leukemia (AML) with an inv(16)(p13q22) or t(16;16)(p13;q22) chromosomal abnormality represents one of the most common subtypes...
Rare Cancers
Tue Sep 22, 2020 13:38
Early patterns of functional brain development associated with autism spectrum disorder in tuberous sclerosis complex.
Related Articles Early patterns of functional brain development associated with autism spectrum disorder in tuberous sclerosis complex. Autism Res. 2019 12;12(12):1758-1773 Authors: Dickinson A, Varcin KJ, Sahin M, Nelson CA, Jeste SS Abstract Tuberous sclerosis complex (TSC) is a rare genetic disorder that confers a high risk for autism spectrum disorders (ASD), with behavioral predictors of ASD emerging early in life. Deviations in structural...
Rare Cancers
Tue Sep 22, 2020 13:38
Noninvasive Detection of Microsatellite Instability and High Tumor Mutation Burden in Cancer Patients Treated with PD-1 Blockade.
Related Articles Noninvasive Detection of Microsatellite Instability and High Tumor Mutation Burden in Cancer Patients Treated with PD-1 Blockade. Clin Cancer Res. 2019 12 01;25(23):7024-7034 Authors: Georgiadis A, Durham JN, Keefer LA, Bartlett BR, Zielonka M, Murphy D, White JR, Lu S, Verner EL, Ruan F, Riley D, Anders RA, Gedvilaite E, Angiuoli S, Jones S, Velculescu VE, Le DT, Diaz LA, Sausen M Abstract PURPOSE: Microsatellite instability...
Rare Cancers
Tue Sep 22, 2020 13:38
Response to Anti-EGFR Therapy in Patients with BRAF non-V600-Mutant Metastatic Colorectal Cancer.
Related Articles Response to Anti-EGFR Therapy in Patients with BRAF non-V600-Mutant Metastatic Colorectal Cancer. Clin Cancer Res. 2019 12 01;25(23):7089-7097 Authors: Yaeger R, Kotani D, Mondaca S, Parikh AR, Bando H, Van Seventer EE, Taniguchi H, Zhao H, Thant CN, de Stanchina E, Rosen N, Corcoran RB, Yoshino T, Yao Z, Ebi H Abstract PURPOSE: While mutations in BRAF in metastatic colorectal cancer (mCRC) most commonly occur at the V600...
Rare Cancers
Tue Sep 22, 2020 13:38
The clinical characteristics and molecular mechanism of pituitary adenoma associated with meningioma.
Related Articles The clinical characteristics and molecular mechanism of pituitary adenoma associated with meningioma. J Transl Med. 2019 10 29;17(1):354 Authors: Zhu H, Miao Y, Shen Y, Guo J, Xie W, Zhao S, Dong W, Zhang Y, Li C Abstract BACKGROUND: Pituitary adenoma and meningioma are the most common benign tumors in the central nervous system. Pituitary adenoma associated with meningioma (PAM) is a rare disease and the clinical features...
Rare Cancers
Tue Sep 22, 2020 13:38
Prognostic Factors of Acinar Cell Carcinomas: A Study of 44 Patients.
Related Articles Prognostic Factors of Acinar Cell Carcinomas: A Study of 44 Patients. Pancreas. 2019 Nov/Dec;48(10):1393-1396 Authors: Egal A, Cros J, Svrcek M, Chiche L, Belleannee G, Poizat F, Jouffret L, Maire F, de Mestier L, Hammel P Abstract OBJECTIVES: Acinar cell carcinoma is a rare tumor of the pancreas. Our current series aimed to assess the clinical and morphological features of pancreatic acinar cell carcinoma and to evaluate the...
Rare Cancers
Tue Sep 22, 2020 13:38
A new indole glycoside from Kitasatospora sp. MG372-hF19 carrying a 6-deoxy-α-L-talopyranose moiety.
Related Articles A new indole glycoside from Kitasatospora sp. MG372-hF19 carrying a 6-deoxy-α-L-talopyranose moiety. J Antibiot (Tokyo). 2020 03;73(3):167-170 Authors: Kohda Y, Sakamoto S, Otsuka Y, Sawa R, Kubota Y, Igarashi M, Muramatsu H, Iijima M, Kawada M Abstract Small cell lung cancer (SCLC) is a severe malignancy with early and widespread metastasis, and novel therapeutic drugs are needed. To identify cytotoxic natural compounds against...
Rare Cancers
Tue Sep 22, 2020 13:38
Intravascular Leiomyomatosis Extending to Right Atrium: A Rare Caused Syncope.
Related Articles Intravascular Leiomyomatosis Extending to Right Atrium: A Rare Caused Syncope. Ann Vasc Surg. 2020 May;65:287.e7-287.e10 Authors: Xu Y, Gao X, Yang C, Liu J, Jin B, Shang D Abstract Intravascular leiomyomatosis (IVL) is a variant of leiomyoma characterized by intravascular proliferation of a histologically benign smooth muscle tumor extending beyond the uterus into distant great vessels or the heart. It is a rare disease and...
Rare Cancers
Tue Sep 22, 2020 13:38
Longitudinal whole-genome sequencing reveals the evolution of MPAL.
Related Articles Longitudinal whole-genome sequencing reveals the evolution of MPAL. Cancer Genet. 2020 01;240:59-65 Authors: Zhang Y, Kang Z, Lv D, Zhang X, Liao Y, Li Y, Liu R, Li P, Tong M, Tian J, Shao Y, Huang C, Ge D, Zhang J, Bai W, Wang Y, Liu Q, Li Z, Yan J Abstract PURPOSE: Mixed phenotype acute leukemia (MPAL) is a rare subtype of acute leukemia and its progressive genomic basis over time remains unclear. We aimed to investigate...
Rare Cancers
Tue Sep 22, 2020 13:38
Utility of copy number variants in the classification of intracranial ependymoma.
Related Articles Utility of copy number variants in the classification of intracranial ependymoma. Cancer Genet. 2020 01;240:66-72 Authors: Evenson M, Cai C, Hucthagowder V, McNulty S, Neidich J, Kulkarni S, Dahiya S Abstract Ependymomas are neuroepithelial tumors that differentiate along the ependymal cell lineage, a lining of the ventricles of the brain and the central canal of the spinal cord. They are rare in adults, but account for around...
Rare Cancers
Tue Sep 22, 2020 13:38
Pediatric gastrointestinal stromal tumor: Report of two novel patients harboring germline variants in SDHB and SDHC genes.
Related Articles Pediatric gastrointestinal stromal tumor: Report of two novel patients harboring germline variants in SDHB and SDHC genes. Cancer Genet. 2020 02;241:61-65 Authors: Rinelli M, Agolini E, Milano GM, Russo I, Crocoli A, De Vito R, Di Giannatale A, Di Paolo PL, Novelli A Abstract Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract and rarely occur in pediatric patients. 85%...
Rare Cancers
Tue Sep 22, 2020 13:38
Widely metastatic glioblastoma with BRCA1 and ARID1A mutations: a case report.
Related Articles Widely metastatic glioblastoma with BRCA1 and ARID1A mutations: a case report. BMC Cancer. 2020 Jan 20;20(1):47 Authors: Umphlett M, Shea S, Tome-Garcia J, Zhang Y, Hormigo A, Fowkes M, Tsankova NM, Yong RL Abstract BACKGROUND: Glioblastoma (GBM) is a highly malignant brain neoplasm with poor survival. Despite its aggressive nature, metastatic spread of GBM is identified only rarely. While the molecular alterations associated...
Rare Cancers
Tue Sep 22, 2020 13:38
Outcomes of rare patients with a primary cutaneous CD30+ lymphoproliferative disorder developing extracutaneous disease.
Related Articles Outcomes of rare patients with a primary cutaneous CD30+ lymphoproliferative disorder developing extracutaneous disease. Blood. 2020 03 05;135(10):769-773 Authors: Melchers RC, Willemze R, Vermaat JSP, Jansen PM, Daniëls LA, Putter H, Bekkenk MW, de Haas ERM, Horvath B, van Rossum MM, Sanders CJG, Veraart JCJM, Vermeer MH, Quint KD PMID: 31977038 [PubMed - indexed for MEDLINE]
Rare Cancers
Tue Sep 22, 2020 13:38
Prophylactic ligation of the thoracic duct branch prevents chylothorax after pulmonary resection for right lung cancer.
Related Articles Prophylactic ligation of the thoracic duct branch prevents chylothorax after pulmonary resection for right lung cancer. Surg Today. 2020 Aug;50(8):881-888 Authors: Liu Z, Du M, Liang Y, Ju S, Li X, Gao Y Abstract PURPOSE: Chylothorax is a rare and challenging complication of thoracic surgery. Whereas most current studies focus on postoperative treatment and preventative measures for esophageal cancer surgery, the current study...
Rare Cancers
Tue Sep 22, 2020 13:38
[A Rare Case of Pulmonary Epithelial-myoepithelial Carcinoma: Case Report and Literature Review].
Related Articles [A Rare Case of Pulmonary Epithelial-myoepithelial Carcinoma: Case Report and Literature Review]. Zhongguo Fei Ai Za Zhi. 2020 Feb 20;23(2):127-132 Authors: Chen L, Li Q, Fu G, Ge M Abstract BACKGROUND: Pulmonary epithelial-myoepithelial carcinoma is a very rare type of salivary gland lung tumor. No standard treatment plan yet. This article intends to analyze the clinical characteristics of pulmonary epithelial-myoepithelial...
Rare Cancers
Tue Sep 22, 2020 13:38
Haemocholecyst related to gallbladder malignancy.
Related Articles Haemocholecyst related to gallbladder malignancy. Trop Doct. 2020 Jul;50(3):243-245 Authors: Ray S, Ghosh R, Khamrui S, Kumar Das A, Saha S, Kumar D Abstract A haemocholecyst is a clot-filled gallbladder caused by bleeding into its lumen. It is a rare entity with fewer than 50 cases reported in the English literature. Preoperative diagnosis is often not possible even with good quality cross-sectional imaging. Here, we present...
Rare Cancers
Tue Sep 22, 2020 13:38
Cervical thyroid remnant consistent with papillary carcinoma as an incidental finding in a patient with benign total thyroidectomy ten years prior.
Related Articles Cervical thyroid remnant consistent with papillary carcinoma as an incidental finding in a patient with benign total thyroidectomy ten years prior. Pol Przegl Chir. 2019 Jul 16;92(1):52-54 Authors: Ruano Campos A, Rivera Alonso D, Ochagavía Cámara S Abstract BACKGROUND: Differential diagnosis of a cervical lesion corresponding with papillary thyroid carcinoma (PTC) after benign total thyroidectomy can be a real challenge. ...
Rare Cancers
Tue Sep 22, 2020 13:38
Gallbladder GIST: A review of literature.
Related Articles Gallbladder GIST: A review of literature. Pol Przegl Chir. 2019 Nov 05;92(1):34-37 Authors: Gupta A Abstract Mesenchymal tumors of the gallbladder are rarely encountered in clinical practice. The Gastrointestinal Stromal Tumor (GIST) of the gallbladder is rarely encountered. These tumors most commonly arise from the interstitial cells of Cajal (ICC), the pacemakers of the intestinal system. There can be benign as well as malignant...
Rare Cancers
Tue Sep 22, 2020 13:38
Transcatheter arterial infusion of anti-programmed cell death 1 antibody pembrolizumab combined with temozolomide or nab-paclitaxel in patient with primary anorectal malignant melanoma: Four case reports.
Related Articles Transcatheter arterial infusion of anti-programmed cell death 1 antibody pembrolizumab combined with temozolomide or nab-paclitaxel in patient with primary anorectal malignant melanoma: Four case reports. J Cancer Res Ther. 2020;16(2):387-392 Authors: Chen S, Zhang X, Shen L, Qi H, Ma W, Cao F, Xie L, Song Z, Wu Y, Li D, Wen X, Fan W Abstract Primary anorectal malignant melanoma (ARMM) is an extremely rare but aggressive tumor....
Rare Cancers
Tue Sep 22, 2020 13:38
A novel serum miRNA-pair classifier for diagnosis of sarcoma.
Related Articles A novel serum miRNA-pair classifier for diagnosis of sarcoma. PLoS One. 2020;15(7):e0236097 Authors: Jin Z, Liu S, Zhu P, Tang M, Wang Y, Tian Y, Li D, Zhu X, Yan D, Zhu Z Abstract Soft tissue sarcomas (STS) is a set of rare malignant tumor originated from mesoderm. For the prognosis of sarcoma, early diagnosis is important, however, currently no mature and non-invasive method for diagnosis exists. MicroRNAs (miRNAs) are a...
Rare Cancers
Tue Sep 22, 2020 13:38
Clear Cell Carcinoma of the Hard Palate in an Adolescent Patient: A Case Report.
Related Articles Clear Cell Carcinoma of the Hard Palate in an Adolescent Patient: A Case Report. Tokai J Exp Clin Med. 2020 Sep 20;45(3):121-125 Authors: Karakida K, Aoki T, Tajiri T, Takahashi M, Nakanishi Y, Tamura M, Naito H Abstract Clear cell carcinoma is an extremely rare low-grade malignancies occurring in less than 1% of salivary gland tumors. We report a case of clear cell carcinoma of the hard palate in a 15-year-old adolescent patient....
Rare Cancers
Tue Sep 22, 2020 13:38
Role of Transoral Robotic Surgery in the Work-up of the Unknown Primary.
Related Articles Role of Transoral Robotic Surgery in the Work-up of the Unknown Primary. Otolaryngol Clin North Am. 2020 Sep 18;: Authors: de Almeida JR Abstract Unknown primary squamous cell carcinoma metastatic to cervical lymph nodes is a relatively rare tumor presentation, although the incidence may be increasing along with the rising incidence of human papilloma virus-mediated oropharyngeal cancers. Traditional diagnostic methods with...
Rare Cancers
Tue Sep 22, 2020 13:38
Pinna high grade trichoblastic carcinoma, a report.
Related Articles Pinna high grade trichoblastic carcinoma, a report. Clin Pract. 2020 Sep 04;10(3):1204 Authors: Yaacoub E, El Borgi J, Challita R, Sleiman Z, Ghanime G Abstract Trichoblastic carcinoma is a rare malignant hair follicle tumor. It resembles basal cell carcinoma clinically, but different studies emphasize on the importance of differentiating between these two cancers since they have different clinical course which may affect treatment...
Rare Cancers
Tue Sep 22, 2020 13:38
Primary pancreatic tuberculosis mimicking pancreatic body cancer. A case report and review of the literature.
Related Articles Primary pancreatic tuberculosis mimicking pancreatic body cancer. A case report and review of the literature. Ann Med Surg (Lond). 2020 Oct;58:80-83 Authors: Ben Hammouda S, Chaka A, Njima M, Korbi I, Zenati H, Zakhama A, Hadhri R, Zouari K Abstract Isolated pancreatic tuberculosis (PT) is an extremely rare disease, with non-specific clinical characteristics, making the diagnosis often challenging with pancreatic cancers. Here...
Rare Cancers
Tue Sep 22, 2020 13:38
A Patient's Journey With Rare Biphenotypic Hepatocellular Carcinoma and Cholangiocarcinoma.
Related Articles A Patient's Journey With Rare Biphenotypic Hepatocellular Carcinoma and Cholangiocarcinoma. Cureus. 2020 Aug 18;12(8):e9838 Authors: Gersowsky DB, Mohiuddin K, Deasey C, Cipollini J, Gilani M Abstract Combined hepatocellular-cholangiocarcinoma (cHCC-CC) is a rare neoplastic primary liver cancer that is also known as mixed HCC-CC since it portrays characteristics of both hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC). It...
Rare Cancers
Tue Sep 22, 2020 13:38
Case report: Trapezius Fibromatosis in the Elderly - An Extremely Rare Tumor.
Related Articles Case report: Trapezius Fibromatosis in the Elderly - An Extremely Rare Tumor. J Orthop Case Rep. 2020;10(2):92-96 Authors: Ravi P, Suriyakumar SS Abstract Introduction: Musculoskeletal fibromatoses represent a wide spectrum of fibroblastic and myofibroblastic neoplasms with similar pathologic appearances and variable clinical behavior. These lesions are categorized by location (superficial or deep). Deep fibromatosis in adults...
Rare Cancers
Tue Sep 22, 2020 13:38
Somatostatin receptor scintigraphy in the follow up of neuroendocrine neoplasms of appendix.
Related Articles Somatostatin receptor scintigraphy in the follow up of neuroendocrine neoplasms of appendix. World J Clin Cases. 2020 Sep 06;8(17):3697-3707 Authors: Saponjski J, Macut D, Sobic-Saranovic D, Ognjanovic S, Bozic Antic I, Pavlovic D, Artiko V Abstract BACKGROUND: Neuroendocrine tumors of appendix (ANETs) known as carcinoids, are rare endocrine neoplasms originated from enterochromaffin cells of gastrointestinal tract. ANETs are...
Rare Cancers
Tue Sep 22, 2020 13:38
Viral Integration Analysis Reveals Likely Common Clonal Origin of Bilateral HPV16-Positive, p16-Positive Tonsil Tumors.
Related Articles Viral Integration Analysis Reveals Likely Common Clonal Origin of Bilateral HPV16-Positive, p16-Positive Tonsil Tumors. Arch Clin Med Case Rep. 2020;4(4):680-696 Authors: Pinatti LM, Walline HM, Carey TE, Klussmann JP, Huebbers CU Abstract Infections with high-risk human papilloma viruses (HPV) are responsible for a significant number of oropharyngeal squamous cell carcinoma (OPSCC), with infection rates currently rising at...
Rare Cancers
Tue Sep 22, 2020 13:38
An adult case of diffuse midline glioma with H3 K27M mutation.
Related Articles An adult case of diffuse midline glioma with H3 K27M mutation. Neuropathology. 2020 Sep 20;: Authors: Tu JH, Piao YS, Lu DH, Wang LM, Liu L, Bai DY, Han HW, Lin YK, Zhong S Abstract Cartilaginous metaplasia is rare in primary central nervous system (CNS) neoplasms and has not been described in the histone 3 (H3) gene (H3) with a substitution of lysine to methionine (H3 K27M mutant) diffuse midline glioma before. Here, we report...
Rare Cancers
Tue Sep 22, 2020 13:38
Safety and Evidence of Off-Label Use of Approved Drugs at the National Cancer Center Hospital in Japan.
Related Articles Safety and Evidence of Off-Label Use of Approved Drugs at the National Cancer Center Hospital in Japan. JCO Oncol Pract. 2020 Sep 21;:OP2000131 Authors: Bun S, Yonemori K, Sunadoi H, Nishigaki R, Noguchi E, Okusaka T, Nishida T, Fujiwara Y Abstract PURPOSE: In Japan, for pharmaceutical products to be covered by public medical insurance, their efficacy and safety must first be confirmed in clinical trials. To our knowledge, this...
Rare Cancers
Tue Sep 22, 2020 15:39
Natural Killer (NK)//T-Cell Lymphoma, Nasal Type, with Periorbital Involvement: A Case Report and Literature Review.
Related Articles Natural Killer (NK)//T-Cell Lymphoma, Nasal Type, with Periorbital Involvement: A Case Report and Literature Review. Am J Case Rep. 2020 Sep 21;21:e926599 Authors: Lisowska G, Zięba N, Stryjewska-Makuch G, Ścierski W, Miśkiewicz-Orczyk K, Misiołek M Abstract BACKGROUND Extranodal natural killer (NK)/T-cell lymphomas are rare neoplasms that result in the destruction of mid-facial tissues. Infrequently seen in ear, nose, and throat...
Rare Cancers
Tue Sep 22, 2020 13:38
Atypical Chest Computed Tomography Finding of Predominant Interstitial Thickening in a Patient with Coronavirus Disease 2019 (COVID-19) Pneumonia.
Related Articles Atypical Chest Computed Tomography Finding of Predominant Interstitial Thickening in a Patient with Coronavirus Disease 2019 (COVID-19) Pneumonia. Am J Case Rep. 2020 Sep 21;21:e926781 Authors: Lau JYC, Khoo HW, Hui TCH, Kaw GJL, Tan CH Abstract BACKGROUND Coronavirus disease 2019 (COVID-19) is caused by a novel coronavirus, SARS-CoV-2, and is associated with severe respiratory disease. There are extensive publications on the...
pubmed: "am j case rep"[jour...
Tue Sep 22, 2020 13:40
Autoimmune Myelofibrosis in Sjögren's Syndrome: Report of a Case.
Related Articles Autoimmune Myelofibrosis in Sjögren's Syndrome: Report of a Case. Am J Case Rep. 2020 Sep 10;21:e924983 Authors: Kakiuchi S, Takagi I, Akiyama H, Matsuba H, Rikitake J, Kajimoto K, Hayashi Y, Iwata N Abstract BACKGROUND Autoimmune myelofibrosis (AMF) is a rare clinicopathologic entity of bone marrow fibrosis that occurs in association with autoimmune disorders. Steroids are very effective for treatment of AMF and the disease...
pubmed: "am j case rep"[jour...
Tue Sep 22, 2020 13:40
Inhibition of Tropomyosin Receptor Kinase A Signaling Negatively Regulates Megakaryopoiesis and induces Thrombopoiesis.
Related Articles Inhibition of Tropomyosin Receptor Kinase A Signaling Negatively Regulates Megakaryopoiesis and induces Thrombopoiesis. Sci Rep. 2019 02 26;9(1):2781 Authors: Kizilyer A, Singh MV, Singh VB, Suwunnakorn S, Palis J, Maggirwar SB Abstract Neurotrophin signaling modulates the differentiation and function of mature blood cells. The expression of neurotrophin receptors and ligands by hematopoietic and stromal cells of the bone...
pubmed: cell cycle arrest
Tue Sep 22, 2020 13:43
SOX6 blocks the proliferation of BCR-ABL1+ and JAK2V617F+ leukemic cells.
Related Articles SOX6 blocks the proliferation of BCR-ABL1+ and JAK2V617F+ leukemic cells. Sci Rep. 2019 03 04;9(1):3388 Authors: Barbarani G, Fugazza C, Barabino SML, Ronchi AE Abstract SOX6 is a HMG-box transcription factor expressed in a wide range of tissues. Recent data show that SOX6 expression is altered in different cancers, in the majority of cases being downregulated. To date, no data are available about SOX6 role in hematological...
pubmed: cell cycle arrest
Tue Sep 22, 2020 13:43
hsa_circ_0062389 promotes the progression of non-small cell lung cancer by sponging miR-103a-3p to mediate CCNE1 expression.
Related Articles hsa_circ_0062389 promotes the progression of non-small cell lung cancer by sponging miR-103a-3p to mediate CCNE1 expression. Cancer Genet. 2020 02;241:12-19 Authors: She Y, Han Y, Zhou G, Jia F, Yang T, Shen Z Abstract Recently, increasing evidence showed that circular RNAs (circRNAs) play critical roles in tumor progression. However, the roles of hsa_circ_0062389 in non-small cell lung cancer (NSCLC) development remain unclear....
pubmed: cell cycle arrest
Tue Sep 22, 2020 13:43
CpG Oligodeoxynucleotides Induces Apoptosis of Human Bladder Cancer Cells via Caspase-3-Bax/Bcl-2-p53 Axis.
Related Articles CpG Oligodeoxynucleotides Induces Apoptosis of Human Bladder Cancer Cells via Caspase-3-Bax/Bcl-2-p53 Axis. Arch Med Res. 2020 04;51(3):233-244 Authors: Luo Y, Fu X, Ru R, Han B, Zhang F, Yuan L, Men H, Zhang S, Tian S, Dong B, Meng M Abstract OBJECTIVE: To evaluate the anti-cancer effect of unmethylated cytosine-phosphorothioate-guanine (CpG)-containing oligodeoxynucleotides (ODNs) on human bladder cancer UM-UC-3 cells, our...
pubmed: cell cycle arrest
Tue Sep 22, 2020 13:43
Clb3-centered regulations are recurrent across distinct parameter regions in minimal autonomous cell cycle oscillator designs.
Related Articles Clb3-centered regulations are recurrent across distinct parameter regions in minimal autonomous cell cycle oscillator designs. NPJ Syst Biol Appl. 2020 04 03;6(1):8 Authors: Mondeel TDGA, Ivanov O, Westerhoff HV, Liebermeister W, Barberis M Abstract Some biological networks exhibit oscillations in their components to convert stimuli to time-dependent responses. The eukaryotic cell cycle is such a case, being governed by waves...
pubmed: cell cycle arrest
Tue Sep 22, 2020 13:43
Lower Levels of Adiponectin and Its Receptor Adipor1 in the Uveal Melanomas With Monosomy-3.
Related Articles Lower Levels of Adiponectin and Its Receptor Adipor1 in the Uveal Melanomas With Monosomy-3. Invest Ophthalmol Vis Sci. 2020 05 11;61(5):12 Authors: Tura A, Thieme C, Brosig A, Merz H, Ranjbar M, Vardanyan S, Zuo H, Maassen T, Kakkassery V, Grisanti S Abstract Purpose: Adiponectin is an insulin-sensitizing and anticarcinogenic hormone that is encoded by a gene on chromosome 3. Here, we analyzed the expression of adiponectin...
pubmed: cell cycle arrest
Tue Sep 22, 2020 13:43
CDKN1A Gene Expression in Two Multiple Myeloma Cell Lines With Different P53 Functionality.
Related Articles CDKN1A Gene Expression in Two Multiple Myeloma Cell Lines With Different P53 Functionality. Anticancer Res. 2020 Sep;40(9):4979-4987 Authors: Drozdkova DH, Gursky J, Minarik J, Überall I, Kolar Z, Trtkova KS Abstract BACKGROUND/AIM: Multiple myeloma is a highly heterogeneous disease of clonal plasma cells. Histone deacetylase (HDAC) inhibitors are promising anticancer drugs but their precise mechanisms of actions are not well...
pubmed: cell cycle arrest
Tue Sep 22, 2020 13:43
Anti-Cancer Activity of Curcumin on Multiple Myeloma.
Related Articles Anti-Cancer Activity of Curcumin on Multiple Myeloma. Anticancer Agents Med Chem. 2020 Sep 18;: Authors: Mirzaei H, Bagheri H, Ghasemi F, Khoi JM, Pourhanifeh MH, Heyden YV, Mortezapour E, Nikdast A, Jeandet P, Khan H, Sahebkar A Abstract Multiple Myeloma (MM) is the third most common and deadly hematological malignancy, which is characterized by a progressive monoclonal proliferation within the bone marrow. MM is cytogenetically...
pubmed: cell cycle arrest
Tue Sep 22, 2020 13:43
Chloroform Fraction of Methanolic Extract of Seeds of Annona muricata Induce S Phase Arrest and ROS Dependent Caspase Activated Mitochondria Mediated Apoptosis in Triple Negative Breast Cancer.
Related Articles Chloroform Fraction of Methanolic Extract of Seeds of Annona muricata Induce S Phase Arrest and ROS Dependent Caspase Activated Mitochondria Mediated Apoptosis in Triple Negative Breast Cancer. Anticancer Agents Med Chem. 2020 Sep 17;: Authors: George AJ, Kariyil BJ, Ayyappan UPT, Gopalakrishnan A Abstract BACKGROUND: Triple negative breast cancers (TNBCs) are having high morbidity and shorter survival rate in the population....
pubmed: cell cycle arrest
Tue Sep 22, 2020 13:43
Function and transcriptomic dynamics of Sertoli cells during prospermatogonia development in mouse testis.
Related Articles Function and transcriptomic dynamics of Sertoli cells during prospermatogonia development in mouse testis. Reprod Biol. 2020 Sep 17;: Authors: Yan RG, Li BY, Yang QE Abstract In mammals, spermatogonial stem cells (SSCs) arise from a subpopulation of prospermatogonia during neonatal testis development. Currently, molecular mechanisms directing the prospermatogonia to spermatogonial transition are not well understood. In...
pubmed: cell cycle arrest
Tue Sep 22, 2020 13:43
IGF-1 induces cellular senescence in rat articular chondrocytes via Akt pathway activation.
Related Articles IGF-1 induces cellular senescence in rat articular chondrocytes via Akt pathway activation. Exp Ther Med. 2020 Nov;20(5):49 Authors: Zhao LD, Bie LY, Hu L, Zhu ZH, Meng XH, Cong LL, Zhang S, Ma N, Xiao JH Abstract Cellular senescence decreases cell proliferation over time and is characterized by typical markers, including larger cell volume, a flattened morphology, irreversible cell cycle arrest, augmentation of senescence-associated...
pubmed: cell cycle arrest
Tue Sep 22, 2020 13:43
Enhanced fatty acid oxidation mediated by CPT1C promotes gastric cancer progression.
Related Articles Enhanced fatty acid oxidation mediated by CPT1C promotes gastric cancer progression. J Gastrointest Oncol. 2020 Aug;11(4):695-707 Authors: Chen T, Wu G, Hu H, Wu C Abstract Background: Carnitine palmitoyltransferase 1C (CPT1C) is a critical enzyme that catalyzes carnitinylation of fatty acids for transport into mitochondria for β-oxidation. No previous studies have been conducted to explore the prognostic and oncogenic...
pubmed: cell cycle arrest
Tue Sep 22, 2020 13:43
Exosomal Formulation Escalates Cellular Uptake of Honokiol Leading to the Enhancement of Its Antitumor Efficacy.
Related Articles Exosomal Formulation Escalates Cellular Uptake of Honokiol Leading to the Enhancement of Its Antitumor Efficacy. ACS Omega. 2020 Sep 15;5(36):23299-23307 Authors: Kanchanapally R, Khan MA, Deshmukh SK, Srivastava SK, Khushman M, Singh S, Singh AP Abstract Honokiol is a phytochemical isolated from the Magnolia plant. It exhibits significant antitumor activity against a variety of cancer cell types via targeting of critical...
pubmed: cell cycle arrest
Tue Sep 22, 2020 13:43
Bta-miR-34b inhibits proliferation and promotes apoptosis via MEK/ERK pathway by targeting MAP2K1 in bovine primary Sertoli cells.
Related Articles Bta-miR-34b inhibits proliferation and promotes apoptosis via MEK/ERK pathway by targeting MAP2K1 in bovine primary Sertoli cells. J Anim Sci. 2020 Sep 21;: Authors: Zhang L, Ma T, Tao Q, Tan W, Chen H, Liu W, Lin P, Zhou D, Wang A, Jin Y, Tang K Abstract Immature Sertoli cell proliferation determines the final number of mature Sertoli cells and further regulates spermatogenesis. Accumulating evidence demonstrated that...
pubmed: cell cycle arrest
Tue Sep 22, 2020 13:43
Inhibition of BRD4 triggers cellular senescence through suppressing aurora kinases in oesophageal cancer cells.
Related Articles Inhibition of BRD4 triggers cellular senescence through suppressing aurora kinases in oesophageal cancer cells. J Cell Mol Med. 2020 Sep 20;: Authors: Xu JL, Yuan YJ, Lv J, Qi D, Wu MD, Lan J, Liu SN, Yang Y, Zhai J, Jiang HM Abstract Oesophageal cancer is one of the most frequent solid malignancies and the leading cause of cancer-related death around the world. It is urgent to develop novel therapy strategies to improve...
pubmed: cell cycle arrest
Tue Sep 22, 2020 13:43
A novel indenone derivative selectively induces senescence in MDA-MB-231 (breast adenocarcinoma) cells.
Related Articles A novel indenone derivative selectively induces senescence in MDA-MB-231 (breast adenocarcinoma) cells. Chem Biol Interact. 2020 Sep 18;:109250 Authors: Priyanga J, Kumar BS, Mahalakshmi R, Nirekshana K, Vinoth P, Sridharan V, Bhakta-Guha D, Guha G Abstract Triple-negative breast cancer is the most aggressive form of breast cancer with limited intervention options. Moreover, a number of belligerent therapeutic strategies...
pubmed: cell cycle arrest
Tue Sep 22, 2020 15:43
RAI14 silencing suppresses progression of esophageal cancer via the STAT3 pathway.
Related Articles RAI14 silencing suppresses progression of esophageal cancer via the STAT3 pathway. Aging (Albany NY). 2020 Sep 14;12: Authors: Wang J, Cai Y, Luo J, Sun Z, Yu J, Yan F, He X Abstract Esophageal cancer (EC) is an aggressive malignancy that has an unclear molecular pathogenesis. Although retinoic acid induced 14 (RAI14) is involved in various cancer processes, the relationship between EC and RAI14 has not been elucidated....
pubmed: cell cycle arrest
Tue Sep 22, 2020 15:43
Can young vascular neurosurgeons become proficient in microsurgical clip reconstruction in the endovascular era? A Rotterdam cohort spanning two decades with propensity-score matching for complexity.
Related Articles Can young vascular neurosurgeons become proficient in microsurgical clip reconstruction in the endovascular era? A Rotterdam cohort spanning two decades with propensity-score matching for complexity. World Neurosurg. 2020 Sep 18;: Authors: Volovici V, Verploegh ISC, Vos JC, Delwel EJ, Bijvoet HWC, van Putten HP, Schouten JW, Avezaat CJJ, Dirven CMF, Dammers R Abstract BACKGROUND: Little is known about the results of young vascular...
pubmed: "world neurosurg"[jo...
Tue Sep 22, 2020 17:46
Endovascular treatment versus best medical therapy in acute ischemic stroke patients with mild symptoms.
Related Articles Endovascular treatment versus best medical therapy in acute ischemic stroke patients with mild symptoms. World Neurosurg. 2020 Sep 18;: Authors: Nicholson P, Byun JS, Lu H, Hilditch CA, Brinjikji W, Agid R, Casaubon LK, Krings T, Schaafsma JD, Mendes-Pereira V PMID: 32956880 [PubMed - as supplied by publisher]
pubmed: "world neurosurg"[jo...
Tue Sep 22, 2020 17:46
Impact of Systemic Therapy Type and Timing on Intracranial Tumor Control in Patients with Brain Metastasis from Non-Small Cell Lung Cancer Treated With Stereotactic Radiosurgery.
Related Articles Impact of Systemic Therapy Type and Timing on Intracranial Tumor Control in Patients with Brain Metastasis from Non-Small Cell Lung Cancer Treated With Stereotactic Radiosurgery. World Neurosurg. 2020 Sep 18;: Authors: Singh SA, McDermott DM, Mattes MD Abstract OBJECTIVE: Stereotactic radiosurgery (SRS) can effectively control brain metastasis (BRM) from non-small cell lung cancer (NSCLC), though intracranial recurrence from...
pubmed: "world neurosurg"[jo...
Tue Sep 22, 2020 17:46
Rapid evolution and rupture of an incidental aneurysm during hyperdynamic therapy for cerebral vasospasm.
Related Articles Rapid evolution and rupture of an incidental aneurysm during hyperdynamic therapy for cerebral vasospasm. World Neurosurg. 2020 Sep 18;: Authors: Chagoya G, Salehani A, Tabibian BE, Laskay NMB, Fox BM, Omar NB, Thaci B, Bernstock JD, Elsayed GA, Harrigan MR Abstract BACKGROUND: Aneurysmal subarachnoid hemorrhage (aSAH) is associated with high morbidity and mortality. Amongst the most common sequelae of aSAH is delayed cerebral...
pubmed: "world neurosurg"[jo...
Tue Sep 22, 2020 17:46
Evaluating the Impact of Spinal Osteotomy on Surgical Outcomes of Thoracolumbar Deformity Correction.
Related Articles Evaluating the Impact of Spinal Osteotomy on Surgical Outcomes of Thoracolumbar Deformity Correction. World Neurosurg. 2020 Sep 18;: Authors: Varshneya K, Stienen MN, Ho AL, Medress ZA, Fatemi P, Pendharkar AV, Ratliff JK, Veeravagu A Abstract BACKGROUND: In cases of adult spinal deformity (ASD) with severe sagittal malalignment, the use of osteotomies may be necessary in addition to posterior fusion. However, little data exists...
pubmed: "world neurosurg"[jo...
Tue Sep 22, 2020 17:46
Stereotactic Brain Biopsy Hemorrhage Risk Factors and Implications for Post-Operative Care at a Single Institution: An Argument For Post Operative Imaging.
Related Articles Stereotactic Brain Biopsy Hemorrhage Risk Factors and Implications for Post-Operative Care at a Single Institution: An Argument For Post Operative Imaging. World Neurosurg. 2020 Sep 18;: Authors: Barkley AS, Sullivan LT, Gibson AW, Camacho D, Barber JK, Ko AL, Silbergeld DL, Ravanpay AC Abstract OBJECTIVE: To determine pre-operative factors contributing to post-operative hemorrhage after stereotactic biopsy (STB), clinical implications...
pubmed: "world neurosurg"[jo...
Tue Sep 22, 2020 17:46
The History of Anterior and Lateral Approaches to the Lumbar Spine.
Related Articles The History of Anterior and Lateral Approaches to the Lumbar Spine. World Neurosurg. 2020 Sep 18;: Authors: Matur AV, Mejia-Munne JC, Plummer ZJ, Cheng JS, Prestigiacomo CJ Abstract Anterior and lateral approaches to the lumbar spine are commonly used today for a variety of indications. These approaches can ultimately be traced back to early attempts to treat Pott's disease. Evidence of Mycobacterium tuberculosis infection of...
pubmed: "world neurosurg"[jo...
Tue Sep 22, 2020 17:46
Emergency Department Visits Following Suboccipital Decompression for Adult Chiari Malformation Type I.
Related Articles Emergency Department Visits Following Suboccipital Decompression for Adult Chiari Malformation Type I. World Neurosurg. 2020 Sep 18;: Authors: Feghali J, Marinaro E, Xie Y, Chen Y, Li S, Huang J Abstract BACKGROUND: Post-operative Emergency Department (ED) visits following suboccipital decompression in CM-1 patients are not well described. We sought to evaluate the magnitude, etiology, and significance of post-operative ED service...
pubmed: "world neurosurg"[jo...
Tue Sep 22, 2020 17:46
Effect of changes in postoperative intervertebral space height on clinical and radiological outcomes after cervical disc replacement.
Related Articles Effect of changes in postoperative intervertebral space height on clinical and radiological outcomes after cervical disc replacement. World Neurosurg. 2020 Sep 18;: Authors: Abudouaini H, Liu H, Huang C, Wang B, Ding C, Meng Y, Yang Y, Wu T Abstract OBJECTIVES: Narrowing of intervertebral space height (ISH) is an important pathological change in degenerative spinal disease, and ideal intraoperative distraction and postoperative...
pubmed: "world neurosurg"[jo...
Tue Sep 22, 2020 17:46
Telemedicine via Smart Glasses in Critical Care of the Neurosurgical Patient - A COVID-19 Pandemic Preparedness and Response in Neurosurgery.
Related Articles Telemedicine via Smart Glasses in Critical Care of the Neurosurgical Patient - A COVID-19 Pandemic Preparedness and Response in Neurosurgery. World Neurosurg. 2020 Sep 18;: Authors: Munusamy T, Karuppiah R, Faizal A Bahuri N, Sockalingam S, Cham CY, Waran V Abstract OBJECTIVE: The COVID-19 pandemic poses major risks to healthcare workers in neurocritical care. Recommendations are in place to limit medical personnel attending...
pubmed: "world neurosurg"[jo...
Tue Sep 22, 2020 17:46
Neurosurgical Interactive Teaching Series: A Multidisciplinary Educational Approach.
Related Articles Neurosurgical Interactive Teaching Series: A Multidisciplinary Educational Approach. World Neurosurg. 2020 Sep 18;: Authors: Ramos-Fresnedo A, Domingo RA, ReFaey K, Gassie K, Clifton W, Grewal SS, Chen SG, Chaichana KL, Quiñones-Hinojosa A Abstract OBJECTIVE: The goal of this manuscript is to investigate the effects of a multidisciplinary multinational web-based teaching conference on trainee education, research and patient...
pubmed: "world neurosurg"[jo...
Tue Sep 22, 2020 17:46
Ultrasound-Guided Erector Spinae Plane Block vs. modified-Thoracolumbar Interfascial Plane Block for Lumbar Discectomy Surgery: A Randomized, Controlled Study.
Related Articles Ultrasound-Guided Erector Spinae Plane Block vs. modified-Thoracolumbar Interfascial Plane Block for Lumbar Discectomy Surgery: A Randomized, Controlled Study. World Neurosurg. 2020 Sep 18;: Authors: Ciftci B, Ekinci M, Celik EC, Yayik AM, Aydin ME, Ahiskalioglu A Abstract OBJECTIVES: This study aimed to compare the ultrasound (US)-guided erector spinae plane block (ESPB) and modified-thoracolumbar interfascial plane (mTLIP)...
pubmed: "world neurosurg"[jo...
Tue Sep 22, 2020 17:46

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