Related Articles Stromal categorization in early oral tongue cancer. Virchows Arch. 2020 Sep 21;: Authors: Almangush A, Bello IO, Heikkinen I, Hagström J, Haglund C, Kowalski LP, Nieminen P, Coletta RD, Mäkitie AA, Salo T, Leivo I Abstract Stromal categorization has been used to classify many epithelial cancer types. We assessed the desmoplastic reaction and compared its significance with other stromal characteristics in early (cT1-2N0)...
Related Articles A Meta-Analysis of the Association Between the Voice Handicap Index and Objective Voice Analysis. J Speech Lang Hear Res. 2020 Sep 21;:1-11 Authors: Zhao EE, Nguyen SA, Salvador CD, O'Rourke AK Abstract Purpose Dysphonia can be evaluated by both patient-reported quality of life instruments and objective acoustic and aerodynamic analyses. However, less is known about the association between the two metrics. The goal of this...
Related Articles 18F-FDG PET/CT in Osteoradionecrosis of the Hyoid. Clin Nucl Med. 2020 Sep 15;: Authors: Antippa SH, Du L, Price N, Hsu CC Abstract Osteoradionecrosis (ORN) is a well-documented complication following radiation treatment for head and neck malignancy. Facial bones, mainly the mandible, laryngeal cartilage, and skull, are frequently involved sites for ORN. A rare site for ORN is the hyoid, with very limited cases described...
Related Articles Pupil-Sparing Third Nerve Palsy and Papilledema Due to Granulomatosis With Polyangiitis. J Neuroophthalmol. 2020 Sep 11;: Authors: Vosoughi AR, Streutker CJ, Yang SP, Lee JM, Micieli JA PMID: 32956224 [PubMed - as supplied by publisher]
Related Articles Outpatient Posttraumatic Auricle Reconstruction Under Local Anesthesia. J Craniofac Surg. 2020 Sep 08;: Authors: Barbieri D, Familiari M, Indelicato P, Bussi M Abstract We described an outpatient auricle reconstruction in an elderly patient after an accidental facial trauma. The procedure was carried out under local anesthesia given patient's comorbidities and acetylsalicylic acid (ASA) therapy. The patient subsequently...
Related Articles Transseptal Suturing With Turbinate Coblation in Nasal Septoturbinoplasty. J Craniofac Surg. 2020 Sep 08;: Authors: Lee YC, Hsin LJ, Chang CC, Tsai YT, Fang TJ Abstract OBJECTIVE: Transseptal suture-assisted septoplasty and coblation are two techniques that can effectively treat septal deviation and inferior turbinate hypertrophy without the need for post-operative packing. In the existing literature, however, the early...
Related Articles Columellar Wound Immediately After Open Rhinoseptoplasty Treated With Application of DuoDERM Extra Thin. J Craniofac Surg. 2020 Sep 08;: Authors: In SM, An HG, Kim JY, Lee KI Abstract Most patients who undergo open rhinoseptoplasty do not develop any wound at the transcolumellar incision site. However, some patients require wound care immediately post-operation. Dressing is difficult to perform in the columellar region...
Related Articles [Reducing the impact of COVID-19 on radiation oncology units of developing countries: A rapid review and expert consensus]. Medwave. 2020 Sep 07;20(8):e8012 Authors: Montero-Oleas N, Puente-Vallejo R, León-Micheli B, Imbaquingo-Cabrera A, Silva M, Gamarra E, Álvarez-Rodas B, Segovia N, Aldaz-Roldan P, Nuñez-Silva C, Zurita-Vivero K, Carrión A, Molina-Jaramillo J, Rodríguez-Balarezo A, Betancourt Y, De Los Reyes L Abstract ...
Related Articles Lessons learned from open laryngotracheal airway resection and primary anastomosis in high risk patients. PLoS One. 2020;15(9):e0238426 Authors: Dewan K, Berke GS, Chhetri DK Abstract OBJECTIVE: Laryngotracheal stenosis is one of the most difficult conditions treated by the Otolaryngologist. Open resection of stenosis with primary airway anastomosis is the definitive treatment for this condition. However, some patients...
Related Articles Simultaneous maxillary and mandibular reconstruction with a single Osteocutaneous fibula free flap: A description of three cases. Microsurgery. 2020 Sep 21;: Authors: Krane NA, Fagin A, Ghanem TA, Cannady SB, Petrisor D, Wax MK Abstract Large defects that comprise both the maxilla and mandible prove to be difficult reconstructive endeavors and commonly require two free tissue transfers. Three cases are presented to discuss...
Related Articles Management of Zygomaticomaxillary Complex Fractures Utilizing Intraoperative 3-Dimensional Imaging: The ZYGOMAS Protocol. J Oral Maxillofac Surg. 2020 Aug 27;: Authors: Cuddy K, Dierks EJ, Cheng A, Patel A, Amundson M, Bell RB Abstract PURPOSE: Utilization of technology to aid in the assessment, planning, and management of complex craniomaxillofacial injuries is increasingly common. Limited data exist regarding the implication...
Related Articles Silencing circular RNA hsa_circ_009755 promotes growth and metastasis of oral squamous cell carcinoma. Genomics. 2020 Sep 18;: Authors: Zhang B, Wang Z, Shen Y, Yang H Abstract OBJECTIVE: Oral squamous cell carcinoma (OSCC) is a common and rampant malignancy of the head and neck. However, its pathogenesis remains unclear. In this study, we have investigated the effects of circular RNA hsa_circ_009755 on proliferation, migration,...
Related Articles Carotid blowout syndrome after reirradiation for head and neck malignancies: a comprehensive systematic review for a pragmatic multidisciplinary approach. Crit Rev Oncol Hematol. 2020 Aug 25;155:103088 Authors: Alterio D, Turturici I, Volpe S, Ferrari A, Russell-Edu SW, Vischioni B, Mardighian D, Preda L, Gandini S, Marvaso G, Augugliaro M, Durante S, Arculeo S, Patti F, Boccuzzi D, Casbarra A, Starzynska A, Santoni R, Jereczek-Fossa BA ...
Related Articles Concurrent use of aspirin with osimertinib is associated with improved survival in advanced EGFR-mutant non-small cell lung cancer. Lung Cancer. 2020 Sep 09;149:33-40 Authors: Liu X, Hong L, Nilsson M, Hubert SM, Wu S, Rinsurongkawong W, Lewis J, Spelman A, Roth J, Swisher S, He Y, Jack Lee J, Fang B, Heymach JV, Zhang J, Le X Abstract BACKGROUND: Osimertinib is the treatment of choice for advanced EGFR-mutant non-small...
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Related Articles Role of periostin in ECRS. Eur Arch Otorhinolaryngol. 2020 Sep 21;: Authors: Yu L, Wang J, Liu K Abstract Periostin, an extracelluar matrix protein belonging to the fasciclin family, has been reported to play a key role in the process of Th2-inflammation disease. As eoshinophilic chronic rhinosinusitis has a higher incident rate, studies show that periostin has participated in the process of inflammation and remodeling. This...
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Related Articles The impact of liver transplant recipient and donor genetic variability on tacrolimus exposure and transplant outcome. Br J Clin Pharmacol. 2019 09;85(9):2170-2175 Authors: Coller JK, Ramachandran J, John L, Tuke J, Wigg A, Doogue M Abstract This study investigated the effect of recipient and donor genetic variability on dose-adjusted steady-state tacrolimus concentrations (Css ) and clinical outcomes 3 and 6 months after liver...
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Related Articles Peri-orbital surgical emphysema following endoscopic dacryocystorhinostomy. J Laryngol Otol. 2020 Sep 21;:1-3 Authors: Bladen JC, Siah WF, Tan P, Litwin AS, Ali S, Malhotra R Abstract BACKGROUND: Peri-orbital surgical emphysema is a rare complication that can occur after lacrimal surgery. It has only been described in isolated cases, following external dacryocystorhinostomy (n = 2) and Lester Jones tube insertion (n = 1). ...
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Related Articles Tripartite motif-containing 35 (TRIM35) is up-regulated in UUO-induced renal fibrosis animal model. Histol Histopathol. 2020 Sep 21;:18255 Authors: Chen Y, Ding Y, Wang LM Abstract Renal fibrosis has been recognized as a serious health threat in the world because of the high cost of treatment and poor prognosis. However, the molecular mechanism of renal fibrosis is still largely unknown. In this study, we aimed at illustrating...
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Related Articles Age-specific colorectal cancer incidence rate in the world. Jpn J Clin Oncol. 2020 Sep 21;: Authors: Saito E, Hori M PMID: 32954417 [PubMed - as supplied by publisher]
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Related Articles Artery of Percheron pseudoaneurysm. J Clin Neurosci. 2020 Sep 17;: Authors: Ikeda DS, Miller CA PMID: 32951951 [PubMed - as supplied by publisher]
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Related Articles The PROCLIPI international registry of early-stage mycosis fungoides identifies substantial diagnostic delay in most patients. Br J Dermatol. 2019 08;181(2):350-357 Authors: Scarisbrick JJ, Quaglino P, Prince HM, Papadavid E, Hodak E, Bagot M, Servitje O, Berti E, Ortiz-Romero P, Stadler R, Patsatsi A, Knobler R, Guenova E, Child F, Whittaker S, Nikolaou V, Tomasini C, Amitay I, Prag Naveh H, Ram-Wolff C, Battistella M, Alberti-Violetti S, Stranzenbach...
Related Articles Rare Presentation of Herpes Virus Lesions in a Case of Acute Pre-B Lymphoblastic Leukemia Turk J Haematol. 2020 Feb 20;37(1):75-76 Authors: Kaymaz E, Güzelküçük Z, Işık M, Yaralı N PMID: 30468433 [PubMed - indexed for MEDLINE]
Related Articles Neuroma (schwannoma). A rare pancreatic tumor. Pol Przegl Chir. 2019 Feb 07;92(1):48-51 Authors: Witkowski G, Kołos M, Nasierowska-Guttmejer A, Durlik M Abstract INTRODUCTION: Neuroma (Schwannoma in Latin) is an encapsulated, mesenchymal tumor arising from Schwann cells surrounded by nerves. Hence it can be located in any area in the body with passing peripheral nerves. The most common location is the head, neck, and extremities....
Related Articles The effect of oral contraceptive pill cessation on hepatocellular adenoma diameter: A retrospective cohort study. Liver Int. 2019 05;39(5):905-913 Authors: Haring MPD, Gouw ASH, de Haas RJ, Cuperus FJC, de Jong KP, de Meijer VE Abstract BACKGROUND & AIMS: Hepatocellular adenomas (HCA) are rare, hormone-driven, benign liver tumours. HCA >50 mm are associated with haemorrhage and malignant transformation. Guidelines recommend...
Related Articles Clinical management of localized undifferentiated sinonasal carcinoma: our experience and review of the literature. Anticancer Drugs. 2019 03;30(3):308-312 Authors: Perri F, Della Vittoria Scarpati G, Ionna F, Longo F, Montano M, Muto P, Ravo V, Giuliano M, Caponigro F Abstract Undifferentiated sinonasal carcinoma (SNUC) is defined as a small round blue cell tumor that is immunohistochemically distinct from other sinonasal...
Related Articles Intensity-modulated radiation therapy with simultaneous integrated boost for locally advanced breast cancer: a prospective study on toxicity and quality of life. Sci Rep. 2019 02 26;9(1):2759 Authors: Pasquier D, Le Tinier F, Bennadji R, Jouin A, Horn S, Escande A, Tresch E, Chauvet MP, Mailliez A, Crop F, Mirabel X, Lartigau E Abstract Radiotherapy after breast conserving surgery and mastectomy with node positive disease...
Related Articles A rare cause of acute epigastric pain during late pregnancy. Liver Int. 2019 07;39(7):1372 Authors: Zhang YM, Luo YF, Liu GM PMID: 31033113 [PubMed - indexed for MEDLINE]
Related Articles Whole Genome Sequencing of Single Circulating Tumor Cells Isolated by Applying a Pulsed Laser to Cell-Capturing Microstructures. Small. 2019 09;15(37):e1902607 Authors: Kim O, Lee D, Chungwon Lee A, Lee Y, Bae HJ, Lee HB, Kim RN, Han W, Kwon S Abstract Single cell analysis of heterogeneous circulating tumor cells (CTCs), by which the genomic profiles of rare single CTCs are connected to the clinical status of cancer patients,...
Related Articles Precise Size-Based Cell Separation via the Coupling of Inertial Microfluidics and Deterministic Lateral Displacement. Anal Chem. 2019 08 06;91(15):10328-10334 Authors: Xiang N, Wang J, Li Q, Han Y, Huang D, Ni Z Abstract We report here a novel two-stage i-DLD sorter through coupling inertial microfluidics with deterministic lateral displacement (DLD), allowing for precise, continuous, and size-based cell separation. The first...
Related Articles Impact of AAV2 and Hepatitis B Virus Integration Into Genome on Development of Hepatocellular Carcinoma in Patients with Prior Hepatitis B Virus Infection. Clin Cancer Res. 2019 10 15;25(20):6217-6227 Authors: Tatsuno K, Midorikawa Y, Takayama T, Yamamoto S, Nagae G, Moriyama M, Nakagawa H, Koike K, Moriya K, Aburatani H Abstract PURPOSE: Hepatitis B viral (HBV) DNA is frequently integrated into the genomes of hepatocellular...
Detection of a novel CBFB-MYH11 fusion transcript in acute myeloid leukemia M1 with inv(16)(p13q22).
Related Articles Detection of a novel CBFB-MYH11 fusion transcript in acute myeloid leukemia M1 with inv(16)(p13q22). Cancer Genet. 2020 02;241:72-76 Authors: Kurata K, Yamamoto K, Okazaki Y, Noguchi Y, Matsui K, Matsumoto H, Inui Y, Yakushijin K, Ito M, Nakamachi Y, Matsuoka H, Saegusa J, Minami H Abstract Acute myeloid leukemia (AML) with an inv(16)(p13q22) or t(16;16)(p13;q22) chromosomal abnormality represents one of the most common subtypes...
Related Articles Early patterns of functional brain development associated with autism spectrum disorder in tuberous sclerosis complex. Autism Res. 2019 12;12(12):1758-1773 Authors: Dickinson A, Varcin KJ, Sahin M, Nelson CA, Jeste SS Abstract Tuberous sclerosis complex (TSC) is a rare genetic disorder that confers a high risk for autism spectrum disorders (ASD), with behavioral predictors of ASD emerging early in life. Deviations in structural...
Related Articles Noninvasive Detection of Microsatellite Instability and High Tumor Mutation Burden in Cancer Patients Treated with PD-1 Blockade. Clin Cancer Res. 2019 12 01;25(23):7024-7034 Authors: Georgiadis A, Durham JN, Keefer LA, Bartlett BR, Zielonka M, Murphy D, White JR, Lu S, Verner EL, Ruan F, Riley D, Anders RA, Gedvilaite E, Angiuoli S, Jones S, Velculescu VE, Le DT, Diaz LA, Sausen M Abstract PURPOSE: Microsatellite instability...
Related Articles Response to Anti-EGFR Therapy in Patients with BRAF non-V600-Mutant Metastatic Colorectal Cancer. Clin Cancer Res. 2019 12 01;25(23):7089-7097 Authors: Yaeger R, Kotani D, Mondaca S, Parikh AR, Bando H, Van Seventer EE, Taniguchi H, Zhao H, Thant CN, de Stanchina E, Rosen N, Corcoran RB, Yoshino T, Yao Z, Ebi H Abstract PURPOSE: While mutations in BRAF in metastatic colorectal cancer (mCRC) most commonly occur at the V600...
Related Articles The clinical characteristics and molecular mechanism of pituitary adenoma associated with meningioma. J Transl Med. 2019 10 29;17(1):354 Authors: Zhu H, Miao Y, Shen Y, Guo J, Xie W, Zhao S, Dong W, Zhang Y, Li C Abstract BACKGROUND: Pituitary adenoma and meningioma are the most common benign tumors in the central nervous system. Pituitary adenoma associated with meningioma (PAM) is a rare disease and the clinical features...
Related Articles Prognostic Factors of Acinar Cell Carcinomas: A Study of 44 Patients. Pancreas. 2019 Nov/Dec;48(10):1393-1396 Authors: Egal A, Cros J, Svrcek M, Chiche L, Belleannee G, Poizat F, Jouffret L, Maire F, de Mestier L, Hammel P Abstract OBJECTIVES: Acinar cell carcinoma is a rare tumor of the pancreas. Our current series aimed to assess the clinical and morphological features of pancreatic acinar cell carcinoma and to evaluate the...
A new indole glycoside from Kitasatospora sp. MG372-hF19 carrying a 6-deoxy-α-L-talopyranose moiety.
Related Articles A new indole glycoside from Kitasatospora sp. MG372-hF19 carrying a 6-deoxy-α-L-talopyranose moiety. J Antibiot (Tokyo). 2020 03;73(3):167-170 Authors: Kohda Y, Sakamoto S, Otsuka Y, Sawa R, Kubota Y, Igarashi M, Muramatsu H, Iijima M, Kawada M Abstract Small cell lung cancer (SCLC) is a severe malignancy with early and widespread metastasis, and novel therapeutic drugs are needed. To identify cytotoxic natural compounds against...
Related Articles Intravascular Leiomyomatosis Extending to Right Atrium: A Rare Caused Syncope. Ann Vasc Surg. 2020 May;65:287.e7-287.e10 Authors: Xu Y, Gao X, Yang C, Liu J, Jin B, Shang D Abstract Intravascular leiomyomatosis (IVL) is a variant of leiomyoma characterized by intravascular proliferation of a histologically benign smooth muscle tumor extending beyond the uterus into distant great vessels or the heart. It is a rare disease and...
Related Articles Longitudinal whole-genome sequencing reveals the evolution of MPAL. Cancer Genet. 2020 01;240:59-65 Authors: Zhang Y, Kang Z, Lv D, Zhang X, Liao Y, Li Y, Liu R, Li P, Tong M, Tian J, Shao Y, Huang C, Ge D, Zhang J, Bai W, Wang Y, Liu Q, Li Z, Yan J Abstract PURPOSE: Mixed phenotype acute leukemia (MPAL) is a rare subtype of acute leukemia and its progressive genomic basis over time remains unclear. We aimed to investigate...
Related Articles Utility of copy number variants in the classification of intracranial ependymoma. Cancer Genet. 2020 01;240:66-72 Authors: Evenson M, Cai C, Hucthagowder V, McNulty S, Neidich J, Kulkarni S, Dahiya S Abstract Ependymomas are neuroepithelial tumors that differentiate along the ependymal cell lineage, a lining of the ventricles of the brain and the central canal of the spinal cord. They are rare in adults, but account for around...
Related Articles Pediatric gastrointestinal stromal tumor: Report of two novel patients harboring germline variants in SDHB and SDHC genes. Cancer Genet. 2020 02;241:61-65 Authors: Rinelli M, Agolini E, Milano GM, Russo I, Crocoli A, De Vito R, Di Giannatale A, Di Paolo PL, Novelli A Abstract Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract and rarely occur in pediatric patients. 85%...
Related Articles Widely metastatic glioblastoma with BRCA1 and ARID1A mutations: a case report. BMC Cancer. 2020 Jan 20;20(1):47 Authors: Umphlett M, Shea S, Tome-Garcia J, Zhang Y, Hormigo A, Fowkes M, Tsankova NM, Yong RL Abstract BACKGROUND: Glioblastoma (GBM) is a highly malignant brain neoplasm with poor survival. Despite its aggressive nature, metastatic spread of GBM is identified only rarely. While the molecular alterations associated...
Related Articles Outcomes of rare patients with a primary cutaneous CD30+ lymphoproliferative disorder developing extracutaneous disease. Blood. 2020 03 05;135(10):769-773 Authors: Melchers RC, Willemze R, Vermaat JSP, Jansen PM, Daniëls LA, Putter H, Bekkenk MW, de Haas ERM, Horvath B, van Rossum MM, Sanders CJG, Veraart JCJM, Vermeer MH, Quint KD PMID: 31977038 [PubMed - indexed for MEDLINE]
Related Articles Prophylactic ligation of the thoracic duct branch prevents chylothorax after pulmonary resection for right lung cancer. Surg Today. 2020 Aug;50(8):881-888 Authors: Liu Z, Du M, Liang Y, Ju S, Li X, Gao Y Abstract PURPOSE: Chylothorax is a rare and challenging complication of thoracic surgery. Whereas most current studies focus on postoperative treatment and preventative measures for esophageal cancer surgery, the current study...
Related Articles [A Rare Case of Pulmonary Epithelial-myoepithelial Carcinoma: Case Report and Literature Review]. Zhongguo Fei Ai Za Zhi. 2020 Feb 20;23(2):127-132 Authors: Chen L, Li Q, Fu G, Ge M Abstract BACKGROUND: Pulmonary epithelial-myoepithelial carcinoma is a very rare type of salivary gland lung tumor. No standard treatment plan yet. This article intends to analyze the clinical characteristics of pulmonary epithelial-myoepithelial...
Related Articles Haemocholecyst related to gallbladder malignancy. Trop Doct. 2020 Jul;50(3):243-245 Authors: Ray S, Ghosh R, Khamrui S, Kumar Das A, Saha S, Kumar D Abstract A haemocholecyst is a clot-filled gallbladder caused by bleeding into its lumen. It is a rare entity with fewer than 50 cases reported in the English literature. Preoperative diagnosis is often not possible even with good quality cross-sectional imaging. Here, we present...
Related Articles Cervical thyroid remnant consistent with papillary carcinoma as an incidental finding in a patient with benign total thyroidectomy ten years prior. Pol Przegl Chir. 2019 Jul 16;92(1):52-54 Authors: Ruano Campos A, Rivera Alonso D, Ochagavía Cámara S Abstract BACKGROUND: Differential diagnosis of a cervical lesion corresponding with papillary thyroid carcinoma (PTC) after benign total thyroidectomy can be a real challenge. ...
Related Articles Gallbladder GIST: A review of literature. Pol Przegl Chir. 2019 Nov 05;92(1):34-37 Authors: Gupta A Abstract Mesenchymal tumors of the gallbladder are rarely encountered in clinical practice. The Gastrointestinal Stromal Tumor (GIST) of the gallbladder is rarely encountered. These tumors most commonly arise from the interstitial cells of Cajal (ICC), the pacemakers of the intestinal system. There can be benign as well as malignant...
Related Articles Transcatheter arterial infusion of anti-programmed cell death 1 antibody pembrolizumab combined with temozolomide or nab-paclitaxel in patient with primary anorectal malignant melanoma: Four case reports. J Cancer Res Ther. 2020;16(2):387-392 Authors: Chen S, Zhang X, Shen L, Qi H, Ma W, Cao F, Xie L, Song Z, Wu Y, Li D, Wen X, Fan W Abstract Primary anorectal malignant melanoma (ARMM) is an extremely rare but aggressive tumor....
Related Articles A novel serum miRNA-pair classifier for diagnosis of sarcoma. PLoS One. 2020;15(7):e0236097 Authors: Jin Z, Liu S, Zhu P, Tang M, Wang Y, Tian Y, Li D, Zhu X, Yan D, Zhu Z Abstract Soft tissue sarcomas (STS) is a set of rare malignant tumor originated from mesoderm. For the prognosis of sarcoma, early diagnosis is important, however, currently no mature and non-invasive method for diagnosis exists. MicroRNAs (miRNAs) are a...
Related Articles Clear Cell Carcinoma of the Hard Palate in an Adolescent Patient: A Case Report. Tokai J Exp Clin Med. 2020 Sep 20;45(3):121-125 Authors: Karakida K, Aoki T, Tajiri T, Takahashi M, Nakanishi Y, Tamura M, Naito H Abstract Clear cell carcinoma is an extremely rare low-grade malignancies occurring in less than 1% of salivary gland tumors. We report a case of clear cell carcinoma of the hard palate in a 15-year-old adolescent patient....
Related Articles Role of Transoral Robotic Surgery in the Work-up of the Unknown Primary. Otolaryngol Clin North Am. 2020 Sep 18;: Authors: de Almeida JR Abstract Unknown primary squamous cell carcinoma metastatic to cervical lymph nodes is a relatively rare tumor presentation, although the incidence may be increasing along with the rising incidence of human papilloma virus-mediated oropharyngeal cancers. Traditional diagnostic methods with...
Related Articles Pinna high grade trichoblastic carcinoma, a report. Clin Pract. 2020 Sep 04;10(3):1204 Authors: Yaacoub E, El Borgi J, Challita R, Sleiman Z, Ghanime G Abstract Trichoblastic carcinoma is a rare malignant hair follicle tumor. It resembles basal cell carcinoma clinically, but different studies emphasize on the importance of differentiating between these two cancers since they have different clinical course which may affect treatment...
Related Articles Primary pancreatic tuberculosis mimicking pancreatic body cancer. A case report and review of the literature. Ann Med Surg (Lond). 2020 Oct;58:80-83 Authors: Ben Hammouda S, Chaka A, Njima M, Korbi I, Zenati H, Zakhama A, Hadhri R, Zouari K Abstract Isolated pancreatic tuberculosis (PT) is an extremely rare disease, with non-specific clinical characteristics, making the diagnosis often challenging with pancreatic cancers. Here...
Related Articles A Patient's Journey With Rare Biphenotypic Hepatocellular Carcinoma and Cholangiocarcinoma. Cureus. 2020 Aug 18;12(8):e9838 Authors: Gersowsky DB, Mohiuddin K, Deasey C, Cipollini J, Gilani M Abstract Combined hepatocellular-cholangiocarcinoma (cHCC-CC) is a rare neoplastic primary liver cancer that is also known as mixed HCC-CC since it portrays characteristics of both hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC). It...
Related Articles Case report: Trapezius Fibromatosis in the Elderly - An Extremely Rare Tumor. J Orthop Case Rep. 2020;10(2):92-96 Authors: Ravi P, Suriyakumar SS Abstract Introduction: Musculoskeletal fibromatoses represent a wide spectrum of fibroblastic and myofibroblastic neoplasms with similar pathologic appearances and variable clinical behavior. These lesions are categorized by location (superficial or deep). Deep fibromatosis in adults...
Related Articles Somatostatin receptor scintigraphy in the follow up of neuroendocrine neoplasms of appendix. World J Clin Cases. 2020 Sep 06;8(17):3697-3707 Authors: Saponjski J, Macut D, Sobic-Saranovic D, Ognjanovic S, Bozic Antic I, Pavlovic D, Artiko V Abstract BACKGROUND: Neuroendocrine tumors of appendix (ANETs) known as carcinoids, are rare endocrine neoplasms originated from enterochromaffin cells of gastrointestinal tract. ANETs are...
Related Articles Viral Integration Analysis Reveals Likely Common Clonal Origin of Bilateral HPV16-Positive, p16-Positive Tonsil Tumors. Arch Clin Med Case Rep. 2020;4(4):680-696 Authors: Pinatti LM, Walline HM, Carey TE, Klussmann JP, Huebbers CU Abstract Infections with high-risk human papilloma viruses (HPV) are responsible for a significant number of oropharyngeal squamous cell carcinoma (OPSCC), with infection rates currently rising at...
Related Articles An adult case of diffuse midline glioma with H3 K27M mutation. Neuropathology. 2020 Sep 20;: Authors: Tu JH, Piao YS, Lu DH, Wang LM, Liu L, Bai DY, Han HW, Lin YK, Zhong S Abstract Cartilaginous metaplasia is rare in primary central nervous system (CNS) neoplasms and has not been described in the histone 3 (H3) gene (H3) with a substitution of lysine to methionine (H3 K27M mutant) diffuse midline glioma before. Here, we report...
Related Articles Safety and Evidence of Off-Label Use of Approved Drugs at the National Cancer Center Hospital in Japan. JCO Oncol Pract. 2020 Sep 21;:OP2000131 Authors: Bun S, Yonemori K, Sunadoi H, Nishigaki R, Noguchi E, Okusaka T, Nishida T, Fujiwara Y Abstract PURPOSE: In Japan, for pharmaceutical products to be covered by public medical insurance, their efficacy and safety must first be confirmed in clinical trials. To our knowledge, this...
Related Articles Natural Killer (NK)//T-Cell Lymphoma, Nasal Type, with Periorbital Involvement: A Case Report and Literature Review. Am J Case Rep. 2020 Sep 21;21:e926599 Authors: Lisowska G, Zięba N, Stryjewska-Makuch G, Ścierski W, Miśkiewicz-Orczyk K, Misiołek M Abstract BACKGROUND Extranodal natural killer (NK)/T-cell lymphomas are rare neoplasms that result in the destruction of mid-facial tissues. Infrequently seen in ear, nose, and throat...
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Related Articles Atypical Chest Computed Tomography Finding of Predominant Interstitial Thickening in a Patient with Coronavirus Disease 2019 (COVID-19) Pneumonia. Am J Case Rep. 2020 Sep 21;21:e926781 Authors: Lau JYC, Khoo HW, Hui TCH, Kaw GJL, Tan CH Abstract BACKGROUND Coronavirus disease 2019 (COVID-19) is caused by a novel coronavirus, SARS-CoV-2, and is associated with severe respiratory disease. There are extensive publications on the...
Related Articles Autoimmune Myelofibrosis in Sjögren's Syndrome: Report of a Case. Am J Case Rep. 2020 Sep 10;21:e924983 Authors: Kakiuchi S, Takagi I, Akiyama H, Matsuba H, Rikitake J, Kajimoto K, Hayashi Y, Iwata N Abstract BACKGROUND Autoimmune myelofibrosis (AMF) is a rare clinicopathologic entity of bone marrow fibrosis that occurs in association with autoimmune disorders. Steroids are very effective for treatment of AMF and the disease...
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Related Articles Inhibition of Tropomyosin Receptor Kinase A Signaling Negatively Regulates Megakaryopoiesis and induces Thrombopoiesis. Sci Rep. 2019 02 26;9(1):2781 Authors: Kizilyer A, Singh MV, Singh VB, Suwunnakorn S, Palis J, Maggirwar SB Abstract Neurotrophin signaling modulates the differentiation and function of mature blood cells. The expression of neurotrophin receptors and ligands by hematopoietic and stromal cells of the bone...
Related Articles SOX6 blocks the proliferation of BCR-ABL1+ and JAK2V617F+ leukemic cells. Sci Rep. 2019 03 04;9(1):3388 Authors: Barbarani G, Fugazza C, Barabino SML, Ronchi AE Abstract SOX6 is a HMG-box transcription factor expressed in a wide range of tissues. Recent data show that SOX6 expression is altered in different cancers, in the majority of cases being downregulated. To date, no data are available about SOX6 role in hematological...
Related Articles hsa_circ_0062389 promotes the progression of non-small cell lung cancer by sponging miR-103a-3p to mediate CCNE1 expression. Cancer Genet. 2020 02;241:12-19 Authors: She Y, Han Y, Zhou G, Jia F, Yang T, Shen Z Abstract Recently, increasing evidence showed that circular RNAs (circRNAs) play critical roles in tumor progression. However, the roles of hsa_circ_0062389 in non-small cell lung cancer (NSCLC) development remain unclear....
Related Articles CpG Oligodeoxynucleotides Induces Apoptosis of Human Bladder Cancer Cells via Caspase-3-Bax/Bcl-2-p53 Axis. Arch Med Res. 2020 04;51(3):233-244 Authors: Luo Y, Fu X, Ru R, Han B, Zhang F, Yuan L, Men H, Zhang S, Tian S, Dong B, Meng M Abstract OBJECTIVE: To evaluate the anti-cancer effect of unmethylated cytosine-phosphorothioate-guanine (CpG)-containing oligodeoxynucleotides (ODNs) on human bladder cancer UM-UC-3 cells, our...
Related Articles Clb3-centered regulations are recurrent across distinct parameter regions in minimal autonomous cell cycle oscillator designs. NPJ Syst Biol Appl. 2020 04 03;6(1):8 Authors: Mondeel TDGA, Ivanov O, Westerhoff HV, Liebermeister W, Barberis M Abstract Some biological networks exhibit oscillations in their components to convert stimuli to time-dependent responses. The eukaryotic cell cycle is such a case, being governed by waves...
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