Pinitol attenuates LPS-induced pneumonia in experimental animals: Possible role via inhibition of the TLR-4 and NF-κB/IκBα signaling cascade pathway. J Biochem Mol Toxicol. 2020 Sep 14;:e22622 Authors: Fan Y, Wang J, Feng Z, Cao K, Xu H, Liu J Abstract Pneumonia is a chronic disorder of the respiratory system associated with worsening quality of life and a significant economic burden. Pinitol, a plant cyclic polyol, has been documented for...
Tue Sep 15, 2020 15:16
COVID-19: Review of a 21st Century Pandemic from Etiology to Neuro-psychiatric Implications. J Alzheimers Dis. 2020;77(2):459-504 Authors: Yamamoto V, Bolanos JF, Fiallos J, Strand SE, Morris K, Shahrokhinia S, Cushing TR, Hopp L, Tiwari A, Hariri R, Sokolov R, Wheeler C, Kaushik A, Elsayegh A, Eliashiv D, Hedrick R, Jafari B, Johnson JP, Khorsandi M, Gonzalez N, Balakhani G, Lahiri S, Ghavidel K, Amaya M, Kloor H, Hussain N, Huang E, Cormier J, Wesson Ashford...
Tue Sep 15, 2020 15:16
Pilomatrix carcinoma of the male breast: a case report. Int J Clin Exp Pathol. 2020;13(8):2153-2157 Authors: Weng G, Li F, Xu M Abstract Pilomatrix carcinoma (PC) is a rare skin adnexal neoplasm derived from piliferous follicles, usually occurring in the head and neck region. An optimal treatment for PC has not yet been established, while surgery with wide margins is recommended, with radiation therapy (RT) and chemotherapy improving the curative...
Tue Sep 15, 2020 15:16
Management of Cerebrospinal Fluid Rhinorrhea in the Sphenoid Sinus Lateral Recess Through an Endoscopic Endonasal Transpterygoid Approach With Obliteration of the Lateral Recess. Ear Nose Throat J. 2020 Sep 13;:145561320955140 Authors: He C, Zhen HT Abstract BACKGROUND: Cerebrospinal fluid rhinorrhea in the sphenoid sinus lateral recess is a rare occurrence and poses unique challenges due to limited surgical access for surgical repair. ...
Tue Sep 15, 2020 15:16
Related Articles The TLR-4/NF-κB signaling pathway activation in cochlear inflammation of rats with noise-induced hearing loss. Hear Res. 2019 08;379:59-68 Authors: Zhang G, Zheng H, Pyykko I, Zou J Abstract The TLR-4/NF-κB signaling pathway is involved in innate immunity and inflammation induced by trauma. The present study aimed to investigate possible TLR-4/NF-κB signaling pathway activation in the cochlea associated with acoustic trauma...
Tue Sep 15, 2020 15:16
Analytical ChemistryDOI: 10.1021/acs.analchem.0c03571
Mon Sep 14, 2020 07:00
[Epidemic characteristics of hand, foot and mouth disease (HFMD) and the lag effect of average daily temperature on the epidemic of HFMD in Beijing]. Zhonghua Yi Xue Za Zhi. 2020 Sep 15;100(34):2696-2700 Authors: Li K, Wu ZH, Liu GT, Li HT, Wang HZ, Peng YG Abstract Objective: To analyze the epidemic characteristics of hand, foot and mouth disease (HFMD) in Beijing and explore the short-term lag effect of daily average temperature on HFMD....
Tue Sep 15, 2020 15:13
[The effects and immunologic mechanisms of Helicobacter pylori infection on AOM/DSS induced colitis-associated cancer in mice]. Zhonghua Yi Xue Za Zhi. 2020 Sep 15;100(34):2689-2695 Authors: Li LN, Liu Y, Zhang HC, Wu T, Dai Y, Wang WH Abstract Objective: To investigate the effects and potential mechanisms of Helicobacter pylori (H.pylori) infection on azoxymethane (AOM)/dextran sulfate sulphate (DSS) induced colitis-associated cancer (CAC)...
Tue Sep 15, 2020 15:13
[Influence of genetic variation of programmed death-ligand 1 (PD-L1) on the prognosis of patients with non-small cell lung cancer who received platinum-based adjuvant chemotherapy]. Zhonghua Yi Xue Za Zhi. 2020 Sep 15;100(34):2682-2688 Authors: Zhang GW, Cheng RR, Zhang FR, Li P, Chu HY, Song XJ, Zhang GJ Abstract Objective: The aim of present study was to investigate the influence of genetic variation of programmed death-ligand 1 (PD-L1) on...
Tue Sep 15, 2020 15:13
[Relationship between insomnia phenotype and mild cognitive impairment in young and middle-aged patients with obstructive sleep apnea hypopnea syndrome]. Zhonghua Yi Xue Za Zhi. 2020 Sep 15;100(34):2675-2681 Authors: Guo KD, Wang J, Wang QJ, Shen JC, Chen R Abstract Objective: To explore the relationship between insomnia phenotype and mild cognitive impairment (MCI) in young and middle-aged patients with obstructive sleep apnea hypopnea syndrome...
Tue Sep 15, 2020 15:13
[Increased Notch receptors induces CD8(+) T cell exhaustion in patients with prostate cancer]. Zhonghua Yi Xue Za Zhi. 2020 Sep 15;100(34):2669-2674 Authors: Wang RX, Li YF, Hao CH, Fang W Abstract Objective: To investigate Notch receptor expression in CD8(+) T cells in patients with prostate cancer, and to assess the influence of Notch signaling pathway on the function of CD8(+)T cells inpatients with prostate cancer. Methods: Forty-five patients...
Tue Sep 15, 2020 15:13
[Correlation analysis between prostate imaging report and data system score and pathological results of prostate cancer]. Zhonghua Yi Xue Za Zhi. 2020 Sep 15;100(34):2663-2668 Authors: Zhu LY, Ding XF, Huang TB, Luan Y, Guo CH, Xu YZ, Wang F Abstract Objective: To explore the correlation between prostate imaging report and data system (PI-RADS) score and international society of uological pathology (ISUP) grade of prostate cancer (PCa) and...
Tue Sep 15, 2020 15:13
[The preliminary clinical study on radical prostatectomy without preoperative prostate biopsy]. Zhonghua Yi Xue Za Zhi. 2020 Sep 15;100(34):2658-2662 Authors: Yang FY, Li YJ, Han SJ, Chen D, Wu LY, Xiao ZJ, Li CL, Xing NZ Abstract Objective: To investigate the feasibility and safety of minimally invasive radical prostatectomy for prostate cancer patients without preoperative prostate biopsy in the new era of the continuous development of comprehensive...
Tue Sep 15, 2020 15:13
[Risk factors for postoperative intestinal obstruction in patients undergoing robot-assisted laparoscopic radical prostatectomy]. Zhonghua Yi Xue Za Zhi. 2020 Sep 15;100(34):2652-2657 Authors: Cui SH, Zhu HJ, Ma ZL Abstract Objective: To analyze the risk factors of postoperative intestinal obstruction (POI) in patients undergoing robot-assisted laparoscopic radical prostatectomy (RARP). Methods: The clinical data of 573 patients receiving RARP...
Tue Sep 15, 2020 15:13
[Complications and treatment strategies of androgen deprivation therapy for prostate cancer]. Zhonghua Yi Xue Za Zhi. 2020 Sep 15;100(34):2641-2644 Authors: Zhou ZY, Han BM, Yang BY PMID: 32921011 [PubMed - in process]
Tue Sep 15, 2020 15:13
Detrusor Underactivity Model in Rats by Conus Medullaris Transection. J Vis Exp. 2020 Aug 28;(162): Authors: Zheng X, Wu M, Song J, Zhao J Abstract The goal of the presented protocol was to establish a detrusor underactivity (DU) model in the rat through conus medullaris transection. Laminectomy was performed in a total of 40 female Wistar rats (control group: 10 rats; test group: 30 rats) weighing 200-220 g, and the conus medullaris was...
Tue Sep 15, 2020 15:13
Obtaining Human Microglia from Adult Human Brain Tissue. J Vis Exp. 2020 Aug 30;(162): Authors: Agrawal I, Saxena S, Nair P, Jha D, Jha S Abstract Microglia are resident innate immune cells of the central nervous system (CNS). Microglia play a critical role during development, in maintaining homeostasis, and during infection or injury. Several independent research groups have highlighted the central role that microglia play in autoimmune...
Tue Sep 15, 2020 15:13
Histological-Based Stainings using Free-Floating Tissue Sections. J Vis Exp. 2020 Aug 25;(162): Authors: Potts EM, Coppotelli G, Ross JM Abstract Immunohistochemistry is a widely used technique to visualize specific tissue structures as well as protein expression and localization. Two alternative approaches are widely used to handle the tissue sections during the staining procedure, one approach consists of mounting the sections directly...
Tue Sep 15, 2020 15:13
An Emerging Target Paradigm to Evoke Fast Visuomotor Responses on Human Upper Limb Muscles. J Vis Exp. 2020 Aug 25;(162): Authors: Kozak RA, Cecala AL, Corneil BD Abstract To reach towards a seen object, visual information has to be transformed into motor commands. Visual information such as the object's color, shape, and size are processed and integrated within numerous brain areas, then ultimately relayed to the motor periphery. In some...
Tue Sep 15, 2020 15:13
FLIM-FRET Measurements of Protein-Protein Interactions in Live Bacteria. J Vis Exp. 2020 Aug 25;(162): Authors: Manko H, Normant V, Perraud Q, Steffan T, Gasser V, Boutant E, Réal É, Schalk IJ, Mély Y, Godet J Abstract Protein-protein interactions (PPIs) control various key processes in cells. Fluorescence lifetime imaging microscopy (FLIM) combined with Förster resonance energy transfer (FRET) provide accurate information about PPIs in...
Tue Sep 15, 2020 15:13
Imaging and Analysis of Neurofilament Transport in Excised Mouse Tibial Nerve. J Vis Exp. 2020 Aug 31;(162): Authors: Boyer NP, Azcorra M, Jung P, Brown A Abstract Neurofilament protein polymers move along axons in the slow component of axonal transport at average speeds of ~0.35-3.5 mm/day. Until recently the study of this movement in situ was only possible using radioisotopic pulse-labeling, which permits analysis of axonal transport...
Tue Sep 15, 2020 15:13
A Two-Step Strategy that Combines Epigenetic Modification and Biomechanical Cues to Generate Mammalian Pluripotent Cells. J Vis Exp. 2020 Aug 29;(162): Authors: Pennarossa G, Ledda S, Arcuri S, Gandolfi F, Brevini TAL Abstract Cell phenotype can be reversed or modified with different methods, with advantages and limitations that are specific for each technique. Here we describe a new strategy that combines the use of chemical epigenetic...
Tue Sep 15, 2020 15:13
Erratum: A Semiautomated ChIP-Seq Procedure for Large-scale Epigenetic Studies. J Vis Exp. 2020 Sep 14;(163): Authors: Abstract An erratum was issued for: A Semiautomated ChIP-Seq Procedure for Large-scale Epigenetic Studies. An author's name was updated. The name was corrected from: Pandurangan Vijayanad to: Pandurangan Vijayanand. PMID: 32925889 [PubMed - as supplied by publisher]
Tue Sep 15, 2020 15:13
Taking the Next Step: a Neural Coaptation Orthotopic Hind Limb Transplant Model to Maximize Functional Recovery in Rat. J Vis Exp. 2020 Aug 30;(162): Authors: Zheng F, Tully A, Koss KM, Zhang X, Qiu L, Wang JJ, Naved BA, Ivancic DZ, Mathew JM, Wertheim JA, Zhang ZJ Abstract Limb transplant in particular and vascularized composite allotransplant (VCA) in general have wide therapeutic promise that have been stymied by current limitations...
Tue Sep 15, 2020 15:13
Successful In vivo Calcium Imaging with a Head-Mount Miniaturized Microscope in the Amygdala of Freely Behaving Mouse. J Vis Exp. 2020 Aug 26;(162): Authors: Lee HS, Han JH Abstract In vivo real-time monitoring of neuronal activities in freely moving animals is one of key approaches to link neuronal activity to behavior. For this purpose, an in vivo imaging technique that detects calcium transients in neurons using genetically encoded...
Tue Sep 15, 2020 15:13
Induction of Accelerated Atherosclerosis in Mice: The "Wire-Injury" Model. J Vis Exp. 2020 Aug 25;(162): Authors: Curaj A, Zhoujun W, Staudt M, Liehn EA Abstract Atherosclerosis is a proliferative fibro-inflammatory disease developing in the arterial wall, inducing a deficient blood flow or a lack of blood flow. Moreover, by rupture of the defective vascular wall, atherosclerosis induces occlusive thrombus formation, which represents the...
Tue Sep 15, 2020 15:13
Genetic Variant Detection in the CALR gene using High Resolution Melting Analysis. J Vis Exp. 2020 Aug 26;(162): Authors: Pajič T, Belčič Mikič T, Podgornik H, Klun J, Šućurović S, Zver S, Sever M Abstract High resolution melting analysis (HRM) is a powerful method for genotyping and genetic variation scanning. Most HRM applications depend on saturating DNA dyes that detect sequence differences, and heteroduplexes that change the shape...
Tue Sep 15, 2020 15:13
Preparation of Adipose Progenitor Cells from Mouse Epididymal Adipose Tissues. J Vis Exp. 2020 Aug 25;(162): Authors: Cho DS, Doles JD Abstract Obesity and metabolic disorders such as diabetes, heart disease, and cancer, are all associated with dramatic adipose tissue remodeling. Tissue-resident adipose progenitor cells (APCs) play a key role in adipose tissue homeostasis and can contribute to the tissue pathology. The growing use of single...
Tue Sep 15, 2020 15:13
Acute Mouse Brain Slicing to Investigate Spontaneous Hippocampal Network Activity. J Vis Exp. 2020 Aug 28;(162): Authors: Whitebirch AC Abstract Acute rodent brain slicing offers a tractable experimental approach to gain insight into the organization and function of neural circuits with single-cell resolution using electrophysiology, microscopy, and pharmacology. However, a major consideration in the design of in vitro experiments is the...
Tue Sep 15, 2020 15:13
Nuclei Isolation from Fresh Frozen Brain Tumors for Single-Nucleus RNA-seq and ATAC-seq. J Vis Exp. 2020 Aug 25;(162): Authors: Narayanan A, Blanco-Carmona E, Demirdizen E, Sun X, Herold-Mende C, Schlesner M, Turcan S Abstract Adult diffuse gliomas exhibit inter- and intra-tumor heterogeneity. Until recently, the majority of large-scale molecular profiling efforts have focused on bulk approaches that led to the molecular classification...
Tue Sep 15, 2020 15:13
Double Direct Injection of Blood into the Cisterna Magna as a Model of Subarachnoid Hemorrhage. J Vis Exp. 2020 Aug 30;(162): Authors: Pedard M, El Amki M, Lefevre-Scelles A, Compère V, Castel H Abstract Among strokes, subarachnoid hemorrhage (SAH) consecutive to the rupture of a cerebral arterial aneurysm represents 5-9% but is responsible for about 30% of the total stroke-related mortality with an important morbidity in terms of neurological...
Tue Sep 15, 2020 15:13
Quantitative Real-Time PCR Evaluation of microRNA Expressions in Mouse Kidney with Unilateral Ureteral Obstruction. J Vis Exp. 2020 Aug 27;(162): Authors: Yanai K, Kaneko S, Ishii H, Aomatsu A, Ito K, Hirai K, Ookawara S, Ishibashi K, Morishita Y Abstract MicroRNAs (miRNAs) are single stranded, non-coding RNA molecules that typically regulate gene expression at the post-transcriptional level by binding to partially complementary target...
Tue Sep 15, 2020 15:13
Development of a Selective Aortic Arch Perfusion System in a Porcine Model of Exsanguination Cardiac Arrest. J Vis Exp. 2020 Aug 25;(162): Authors: Madurska MJ, Abdou H, Richmond MJ, Elansary NN, Wong PF, Rasmussen TE, Scalea TM, Morrison JJ Abstract Hemorrhage constitutes the majority of potentially preventable deaths from trauma. There is growing interest in endovascular resuscitation techniques such as selective aortic arch perfusion...
Tue Sep 15, 2020 15:13
Isolation and Cultivation of Mandibular Bone Marrow Mesenchymal Stem Cells in Rats. J Vis Exp. 2020 Aug 25;(162): Authors: Hong Y, Xu H, Yang Y, Zhou S, Jin A, Huang X, Dai Q, Jiang L Abstract Here we present an efficient method for isolating and culturing mandibular bone marrow mesenchymal stem cells (mBMSCs) in vitro to rapidly obtain numerous high-quality cells for experimental requirements. mBMSCs could be widely used in therapeutic...
Tue Sep 15, 2020 15:13
Lower-Limb Biomechanical Characteristics Associated with Unplanned Gait Termination Under Different Walking Speeds. J Vis Exp. 2020 Aug 25;(162): Authors: Zhou H, Cen X, Song Y, Ugbolue UC, Gu Y Abstract Gait termination caused by unexpected stimulus is a common occurrence in everyday life. This study presents a protocol to investigate the lower-limb biomechanical changes that occur during unplanned gait termination (UGT) under different...
Tue Sep 15, 2020 15:13
Acupuncture in a Rat Model of Asthma. J Vis Exp. 2020 Aug 25;(162): Authors: Zhou DD, Zhang GQ, Zhao QY, Cheng M, Lu J, Wang Y, Xu YD, Chen YJ, Yang YQ, Yin LM Abstract A high platform can fix rats without restriction and completely expose the acupoints on the back during acupuncture manipulation. This article describes methods for the fabrication of the high platform, establishes a rat model of asthma and measures changes in respiratory...
Tue Sep 15, 2020 15:13
Establishment of Acute Pontine Infarction in Rats by Electrical Stimulation. J Vis Exp. 2020 Aug 27;(162): Authors: Luo M, Tang X, Zhu J, Qiu Z, Jiang Y Abstract Pontine infarction is the most common stroke subtype in the posterior circulation, while there lacks a rodent model mimicking pontine infarction. Provided here is a protocol for successfully establishing a rat model of acute pontine infarction. Rats weighing about 250 g are used,...
Tue Sep 15, 2020 15:13
Preparation of Virus-Enriched Inoculum for Oral Infection of Honey Bees (Apis Mellifera). J Vis Exp. 2020 Aug 26;(162): Authors: Hsieh EM, Carrillo-Tripp J, Dolezal AG Abstract Honey bees are of great ecological and agricultural importance around the world but are also subject to a variety of pressures that negatively affect bee health, including exposure to viral pathogens. Such viruses can cause a wide variety of devastating effects...
Tue Sep 15, 2020 15:13
Immunostaining of Whole-Mount Drosophila Testes for 3D Confocal Analysis of Large Spermatocytes. J Vis Exp. 2020 Aug 27;(162): Authors: Raich N, Contremoulins V, Karess RE Abstract Drosophila testes are a powerful model system for studying biological processes including stem cell biology, nuclear architecture, meiosis and sperm development. However, immunolabeling of the whole Drosophila testis is often associated with significant non-uniformity...
Tue Sep 15, 2020 15:13
Publication date: November 2020Source: International Immunopharmacology, Volume 88Author(s): Xiujing Feng, Wen Yu, Lingsen Cao, Fanda Meng, Mulin Cong
Tue Sep 15, 2020 15:11
The ranging of amino acids substitution matrices of various types in accordance with the alignment accuracy criterion. BMC Bioinformatics. 2020 Sep 14;21(Suppl 11):294 Authors: Polyanovsky V, Lifanov A, Esipova N, Tumanyan V Abstract BACKGROUND: The alignment of character sequences is important in bioinformatics. The quality of this procedure is determined by the substitution matrix and parameters of the insertion-deletion penalty function....
Tue Sep 15, 2020 15:09
Limit cycles in models of circular gene networks regulated by negative feedback loops. BMC Bioinformatics. 2020 Sep 14;21(Suppl 11):255 Authors: Likhoshvai VA, Golubyatnikov VP, Khlebodarova TM Abstract BACKGROUND: The regulatory feedback loops that present in structural and functional organization of molecular-genetic systems and the phenomenon of the regulatory signal delay, a time period between the moment of signal reception and its implementation,...
Tue Sep 15, 2020 15:09
A novel approach for predicting protein S-glutathionylation. BMC Bioinformatics. 2020 Sep 14;21(Suppl 11):282 Authors: Anashkina AA, Poluektov YM, Dmitriev VA, Kuznetsov EN, Mitkevich VA, Makarov AA, Petrushanko IY Abstract BACKGROUND: S-glutathionylation is the formation of disulfide bonds between the tripeptide glutathione and cysteine residues of the protein, protecting them from irreversible oxidation and in some cases causing change in...
Tue Sep 15, 2020 15:09
Review of medical image recognition technologies to detect melanomas using neural networks. BMC Bioinformatics. 2020 Sep 14;21(Suppl 11):270 Authors: Efimenko M, Ignatev A, Koshechkin K Abstract BACKGROUND: Melanoma is one of the most aggressive types of cancer that has become a world-class problem. According to the World Health Organization estimates, 132,000 cases of the disease and 66,000 deaths from malignant melanoma and other forms of...
Tue Sep 15, 2020 15:09
ANDDigest: a new web-based module of ANDSystem for the search of knowledge in the scientific literature. BMC Bioinformatics. 2020 Sep 14;21(Suppl 11):228 Authors: Ivanisenko TV, Saik OV, Demenkov PS, Ivanisenko NV, Savostianov AN, Ivanisenko VA Abstract BACKGROUND: The rapid growth of scientific literature has rendered the task of finding relevant information one of the critical problems in almost any research. Search engines, like Google Scholar,...
Tue Sep 15, 2020 15:09
Bioinformatics research at SBB-2019. BMC Bioinformatics. 2020 Sep 14;21(Suppl 11):366 Authors: Orlov YL, Galieva ER, Tatarinova TV PMID: 32921301 [PubMed - in process]
Tue Sep 15, 2020 15:09
On the dynamical aspects of local translation at the activated synapse. BMC Bioinformatics. 2020 Sep 14;21(Suppl 11):258 Authors: Khlebodarova TM, Kogai VV, Likhoshvai VA Abstract BACKGROUND: The key role in the dynamic regulation of synaptic protein turnover belongs to the Fragile X Mental Retardation Protein, which regulates the efficiency of dendritic mRNA translation in response to stimulation of metabotropic glutamate receptors at excitatory...
Tue Sep 15, 2020 15:09
Publication date: Available online 15 September 2020Source: Sleep MedicineAuthor(s): Yulia Roitblat, Jacob Burger, Michael Vaiman, Liliia Nehuliaieva, Noa Buchris, Michael Shterenshis, Orit Rome, Leor Sinai, Rachelle Sevitt, Ayela Meroody, Marnie Nadolne, D. Psy, Philip Shilco, Geoffrey P. Jacobs, Michael Shterenshis, Abby Sosnow, Maya Foonberg, Elijah Faridnia, Ariel Emrani, Liana Hiekali
Tue Sep 15, 2020 15:09
Publication date: Available online 15 September 2020Source: Sleep MedicineAuthor(s): Li Zhou, Xiaoxiao Shan, Yating Peng, Guiqian Liu, Wenbin Guo, Hong Luo, Huabing Li, Dandan Zong, Ruoyun Ouyang
Tue Sep 15, 2020 15:09
Abstract Purpose The primary aim of this systematic review and meta-analysis was to determine the association between gestational diabetes mellitus (GDM) and metabolic syndrome (MetS) in women and children. Our secondary aim was to assess the development of MetS with respect to the elapsed time postpartum at which MetS was diagnosed. Methods This review...
Tue Sep 15, 2020 03:00
Abstract The philosophical investigation of perceptual illusions can generate fruitful insights in the study of subjective time consciousness. However, the way illusions are interpreted is often controversial. Recently, proponents of the so-called dynamic snapshot theory have appealed to the Waterfall Illusion, a kind of motion aftereffect, to support a particular view of temporal consciousness according to which experience is structured as a series of instantaneous snapshots with...
Tue Sep 15, 2020 03:00
62 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human homeostasis These pubmed results were generated on 2020/09/15PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Tue Sep 15, 2020 15:03
23 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "Front Oncol"[jour] These pubmed results were generated on 2020/09/15PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Tue Sep 15, 2020 15:01
Trial Design Challenges and Approaches for Precision Oncology in Rare Tumors: Experiences of the Children's Oncology Group. JCO Precis Oncol. 2019;3: Authors: Renfro LA, Ji L, Piao J, Onar-Thomas A, Kairalla JA, Alonzo TA Abstract In the United States, cancer remains the leading cause of disease-related death in children. Although survival from any pediatric cancer has improved dramatically during past decades, a number of cancers continue...
Tue Sep 15, 2020 15:00
Precision Oncology and the Universal Health Coverage System in Japan. JCO Precis Oncol. 2019;3: Authors: Ebi H, Bando H Abstract Although precision oncology is transforming clinical management of patients with cancer, many hospitals face challenges to effectively implement precision oncology. In addition, the cost and time exerted for genomic profiling needs to be balanced with expectations of benefit for each patient. This article summarizes...
Tue Sep 15, 2020 15:00
Phyllodes Tumors of the Breast: A Literature Review. Cureus. 2020 Sep 07;12(9):e10288 Authors: Rayzah M Abstract Phyllodes tumors (PTs) of the breast are considered a rare fibroepithelial neoplasms of the breast and are considered a challenging for both pathologists and surgeons. The World Health Organization (WHO) has classified PTs histologically as benign, borderline, and malignant. PTs can be detected in all ages; however, the median age of...
Tue Sep 15, 2020 15:00
Desmoplastic Trichoepithelioma: Histopathologic and Immunohistochemical Criteria for Differentiation of a Rare Benign Hair Follicle Tumor From Other Cutaneous Adnexal Tumors. Cureus. 2020 Aug 12;12(8):e9703 Authors: Rahman J, Tahir M, Arekemase H, Murtazaliev S, Sonawane S Abstract Desmoplastic trichoepitheliomas (DTEs) are benign cutaneous neoplasms that originate from the hair follicle and exhibit a preference for the facial region. This...
Tue Sep 15, 2020 15:00
Nodular Spindle Cell Vascular Transformation in Pelvic Lymph Nodes With Discovered on GIST1 (DOG1) Positivity Mimicking Metastatic Gastrointestinal Stromal Tumor. Cureus. 2020 Aug 09;12(8):e9632 Authors: Chai J, Hamilton T, Han-Lee C, Feng X Abstract We present a case report of vascular transformation of lymph node sinuses (VTS) of nodular spindle cell variant. This variation is a rare, benign entity previously described with histopathologic...
Tue Sep 15, 2020 15:00
A Rare Case of Choroid Plexus Papilloma of the Third Ventricle in an Adult. Cureus. 2020 Aug 06;12(8):e9582 Authors: Shah MH, Abdelhady M, Own A, Elsotouhy A Abstract Colloid cysts are the commonest masses of the third ventricle. Third ventricle neoplasms are uncommon. They include tumors arising from the choroid plexus (papillomas, carcinomas), tumors arising from other than the choroid plexus (ependymomas, meningiomas), metastases, and lymphoma....
Tue Sep 15, 2020 15:00
Specific immune landscapes and immune checkpoint expressions in histotypes and molecular subtypes of sarcoma. Oncoimmunology. 2020 Jul 12;9(1):1792036 Authors: Dufresne A, Lesluyes T, Ménétrier-Caux C, Brahmi M, Darbo E, Toulmonde M, Italiano A, Mir O, Le Cesne A, Le Guellec S, Valentin T, Chevreau C, Bonvalot S, Robin YM, Coindre JM, Caux C, Blay JY, Chibon F Abstract Soft tissue sarcomas are a group of rare and aggressive connective tissue...
Tue Sep 15, 2020 15:00
Secretory carcinoma around Stensen's duct misdiagnosed as salivary duct cyst. Int J Clin Exp Pathol. 2020;13(8):2211-2217 Authors: Shibata E, Morita KI, Kayamori K, Maruiwa M, Michi Y, Sato Y, Takeuchi K, Ikeda T, Harada H, Yoda T Abstract Secretory carcinoma (SC) of the salivary gland was identified in 2010, and it is characterized by a specific ETV6 gene arrangement. The most common primary site for SC is the parotid gland; however, SC around...
Tue Sep 15, 2020 15:00
283 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human physiology These pubmed results were generated on 2020/09/15PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Tue Sep 15, 2020 14:58
Liver metastasis from typical meningioma: case report. World Neurosurg. 2020 Sep 11;: Authors: Sheng B, Liu Y, Liu C Abstract BACKGROUND: Extracranial metastases from atypical meningioma are not usual found, sometime found in lung, bone or scalp, but found in the liver were extremely rare. CASE DESCRIPTION: We report a case of 55-years old patient with atypical meningioma, treated with surgical resection in 2005 year, and accepted...
Tue Sep 15, 2020 14:52
Corrigendum to 'Relationship Between Arterial Blood Pressure During Trigeminal Nerve Combing and Surgical Outcome in Patients with Trigeminal Neuralgia' [World Neurosurgery 137 (2020) e98-e105]. World Neurosurg. 2020 Aug 30;: Authors: Liu J, Wu G, Jiang Y, Li L, Wang D, Liu R PMID: 32921624 [PubMed - as supplied by publisher]
Tue Sep 15, 2020 14:52
Azithromycin for chronic eosinophilic rhinosinusitis with nasal polyp: a placebo-controlled trial. Rhinology. 2020 Sep 14;: Authors: de Oliveira IS, Guimaraes AF, Arantes Pêgas GF, Machado CJ, Cassali GD, Barbosa Nunes F, Gonçalves Becker HM, Santos Guimarães RE Abstract BACKGROUND: Chronic eosinophilic rhinosinusitis with nasal polyps (CRSwNP eosinophilic) is characterised by the formation of benign and bilateral nasal polyps. We aimed to...
Tue Sep 15, 2020 14:51
Individual importance of olfaction decreases with duration of smell loss. Rhinology. 2020 Sep 14;: Authors: Liu DT, Besser G, Prem B, Speth MM, Sedaghat AR, Mueller C Abstract BACKGROUND: The personal importance of a lost neurologic - motor or sensory - function in several conditions has been shown to decrease as the afflicted patient becomes accustomed to not having that function. It is unknown how the importance of olfaction changes with...
Tue Sep 15, 2020 14:51
Comparing nasal physiology after superior ethmoidal and traditional endoscopic anterior cranial base approaches. Rhinology. 2020 Sep 14;: Authors: Patel V, Viswanathan R, Ruffner R, Peris-Celda M, Pinheiro-Neto CD Abstract To the Editor: Endoscopic endonasal approaches can be effective for treating a wide variety of skull base pathologies with reduced complica- tions compared with open approaches(1). The traditional endo- scopic endonasal anterior...
Tue Sep 15, 2020 14:51
Cervical cystic lymphangiomas are rare benign tumors that pose a formidable challenge to surgeons confronted with managing this uncommon entity. Due to the intimacy with which these cystic lesions blend with critical cervical structures, a considerable number of patients who undergo surgical management are often plagued with recurrence and morbidity. As a result, doxycycline sclerotherapy has become an attractive, safe, and effective alternative as a primary treatment modality in a select group of...
Tue Sep 15, 2020 06:20
Severe acute pancreatitis concurrent with lethal rupture of cerebral aneurysm: A case report and review of the literature. Int J Surg Case Rep. 2020 Aug 18;75:89-93 Authors: Xu Y, Wang J, Zhang Z Abstract INTRODUCTION: With high incidence and mortality, severe acute pancreatitis (SAP) is an inflammatory disease of pancreas. When concurrent with systemic inflammatory response syndrome (SIRS), multiple organ failure syndrome (MODS) or pancreatic...
Tue Sep 15, 2020 14:43
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