Related Articles Efficiency of Bacillus subtilis metabolism of sugar alcohols governs its probiotic effect against cariogenic Streptococcus mutans. Artif Cells Nanomed Biotechnol. 2020 Dec;48(1):1222-1230 Authors: Duanis-Assaf D, Steinberg D, Shemesh M Abstract Bacillus subtilis is a Gram-positive probiotic bacterium that successfully colonises plant roots due to its ability to utilise various sugars. The vast probiotic potential of B....
Tue Sep 22, 2020 14:05
Abstract Background Gnotobiotic mice colonized with microbiota from patients with irritable bowel syndrome (IBS) and comorbid anxiety (IBS+A) display gut dysfunction and anxiety‐like behavior compared to mice colonized with microbiota from healthy volunteers. Using this model, we tested the therapeutic potential of the probiotic yeast Saccharomyces boulardii strain CNCM I‐745 (S. bou) and investigated underlying mechanisms. Methods Germ‐free Swiss Webster mice were colonized with fecal...
Mon Sep 21, 2020 13:35
Related Articles Development of a Pediatric Fertility Preservation Program: A Report From the Pediatric Initiative Network of the Oncofertility Consortium. J Adolesc Health. 2019 05;64(5):563-573 Authors: Moravek MB, Appiah LC, Anazodo A, Burns KC, Gomez-Lobo V, Hoefgen HR, Jaworek Frias O, Laronda MM, Levine J, Meacham LR, Pavone ME, Quinn GP, Rowell EE, Strine AC, Woodruff TK, Nahata L Abstract Infertility is known to decrease quality of...
Tue Sep 22, 2020 14:15
Related Articles Sequential Versus Concurrent Thoracic Radiotherapy in Combination With Cisplatin and Etoposide for N3 Limited-Stage Small-Cell Lung Cancer. Cancer Control. 2020 Jan-Dec;27(1):1073274820956619 Authors: Wang Z, Wan J, Liu C, Li L, Dong X, Geng H Abstract At present, concurrent chemoradiotherapy (CRT) is considered the standard treatment of limited-stage small cell lung cancer (LS-SCLC). However, LS-SCLC is highly heterogeneous...
Tue Sep 22, 2020 14:15
Related Articles Development, implementation, and outcomes of a simulation-based medical education (SBME) prostate brachytherapy workshop for radiation oncology residents. Brachytherapy. 2020 Sep 17;: Authors: Mesko S, Chapman BV, Tang C, Kudchadker RJ, Bruno TL, Sanders J, Das P, Pinnix CC, Thaker NG, Frank SJ Abstract PURPOSE: Despite a preponderance of data demonstrating strong clinical outcomes and cost-effectiveness, prostate brachytherapy...
Tue Sep 22, 2020 14:15
Related Articles Organoids as Complex In Vitro Models for Studying Radiation-Induced Cell Recruitment. Cell Mol Bioeng. 2020 Aug;13(4):341-357 Authors: Hacker BC, Rafat M Abstract Patients with triple negative breast cancer (TNBC) typically receive chemotherapy, surgery, and radiation therapy. Although this treatment improves prognosis for most patients, some patients continue to experience recurrence within 5 years. Preclinical studies have...
Tue Sep 22, 2020 14:15
Related Articles Predicting combinations of immunomodulators to enhance dendritic cell-based vaccination based on a hybrid experimental and computational platform. Comput Struct Biotechnol J. 2020;18:2217-2227 Authors: Ahmed R, Crespo I, Tuyaerts S, Bekkar A, Graciotti M, Xenarios I, Kandalaft LE Abstract Dendritic cell (DC)-based vaccines have been largely used in the adjuvant setting for the treatment of cancer, however, despite their proven...
Tue Sep 22, 2020 14:15
Related Articles Impact of immunotherapy use in patients with stage IV pancreatic carcinoma. J Gastrointest Oncol. 2020 Aug;11(4):654-662 Authors: Guddati AK, Komiya T, Patel SJ, Sharma N, Powell E Abstract Background: Most patients with pancreatic cancer have non-resectable disease at the time of diagnosis and usually die within 6-12 months. Despite indications in other solid tumors, the role of immunotherapy (IO) is unknown for late stage,...
Tue Sep 22, 2020 14:15
Related Articles Predictive and prognostic significance of M descriptors of the 8th TNM classification for advanced NSCLC patients treated with immune checkpoint inhibitors. Transl Lung Cancer Res. 2020 Aug;9(4):1053-1066 Authors: Liu S, Zhou F, Liu Z, Xiong A, Jia Y, Zhao S, Zhao C, Li X, Jiang T, Han R, Qiao M, Liu Y, He Y, Li J, Li W, Gao G, Ren S, Su C, Zhou C Abstract Background: A strong association between M descriptors and prognosis...
Tue Sep 22, 2020 14:15
Related Articles Impact of time-to-treatment on overall survival of non-small cell lung cancer patients-an analysis of the national cancer database. Transl Lung Cancer Res. 2020 Aug;9(4):1202-1211 Authors: Anggondowati T, Ganti AK, Islam KMM Abstract Background: The association between time-to-treatment and outcomes for lung cancer has not been conclusively established. In this study, we evaluated the effect of time-to-treatment on the overall...
Tue Sep 22, 2020 14:15
Related Articles PD-L1 as a prognostic biomarker in surgically resectable non-small cell lung cancer: a meta-analysis. Transl Lung Cancer Res. 2020 Aug;9(4):1343-1360 Authors: Tuminello S, Sikavi D, Veluswamy R, Gamarra C, Lieberman-Cribbin W, Flores R, Taioli E Abstract Background: PD-L1 tumor expression has been associated with poor prognosis in a variety of solid tumors, including lung cancer, and represents a validated target for immune...
Tue Sep 22, 2020 14:15
Related Articles Physician treatment of metastatic triple-negative breast cancer in the immuno-oncology era: a discrete choice experiment. Future Oncol. 2020 Sep 21;: Authors: Feinberg B, Hime S, Wojtynek J, Dokubo I, Gajra A, Smith Y, Kish J Abstract Aim: Guidelines list atezolizumab with nab-paclitaxel (ANP) as the preferred first-line (1L) therapy for metastatic triple-negative breast cancer (mTNBC) with PD-L1 expression ≥1%, but which clinical...
Tue Sep 22, 2020 14:15
Related Articles Polatuzumab vedotin, an anti-CD79b antibody-drug conjugate for the treatment of relapsed/refractory diffuse large B-cell lymphoma. Future Oncol. 2020 Sep 21;: Authors: Camus V, Tilly H Abstract Refractory/relapsed diffuse large B-cell lymphoma remains a major unmet medical need with poor outcome, especially for patients considered ineligible for stem cell transplant. Polatuzumab vedotin (PV) is a first-in-class anti-CD79b antibody-drug...
Tue Sep 22, 2020 14:15
Related Articles REVIVE study: a prospective observational study in chemotherapy after nivolumab therapy for advanced gastric cancer. Future Oncol. 2020 Sep 21;: Authors: Narita Y, Shoji H, Kawai S, Mizukami T, Nakamura M, Moriwaki T, Yamanaka T, Sunakawa Y, Kawakami H, Nishina T, Misumi T, Muro K Abstract Nivolumab is an increasingly used standard care treatment for heavily pretreated patients with advanced gastric cancer, with increasing clinical...
Tue Sep 22, 2020 14:15
Related Articles Socioeconomic Status and Melanoma in Canada: A Systematic Review. J Cutan Med Surg. 2020 Sep 21;:1203475420960426 Authors: Li HO, Bailey AJ, Grose E, McDonald JT, Quimby A, Johnson-Obaseki S, Nessim C Abstract As melanoma is one of the leading cancers in average years of life lost per death from disease, screening and early diagnosis are imperative to decrease morbidity and mortality. Socioeconomic status (SES) has been shown...
Tue Sep 22, 2020 14:15
Related Articles Optimizing Health Information Technologies for Symptom Management in Cancer Patients and Survivors: Usability Evaluation. JMIR Form Res. 2020 Sep 21;4(9):e18412 Authors: Lattie EG, Bass M, Garcia SF, Phillips SM, Moreno PI, Flores AM, Smith JD, Scholtens D, Barnard C, Penedo FJ, Cella D, Yanez B Abstract BACKGROUND: Unmanaged cancer symptoms and treatment-related side effects can compromise long-term clinical outcomes and health-related...
Tue Sep 22, 2020 14:15
Related Articles 'I don't talk about my distress to others; I feel that I have to suffer my problems...' Voices of Indian women with breast cancer: a qualitative interview study. Support Care Cancer. 2020 Sep 21;: Authors: Daniel S, Venkateswaran C, Hutchinson A, Johnson MJ Abstract BACKGROUND: Breast cancer is the commonest form of cancer among women globally, including in India. The rising incidence in the developing world is thought to be...
Tue Sep 22, 2020 14:15
Related Articles In the future all accredited radiotherapy physicists should have a PhD. Phys Eng Sci Med. 2020 Sep 21;: Authors: Booth J, Whitaker M, Baldock C PMID: 32955685 [PubMed - as supplied by publisher]
Tue Sep 22, 2020 14:15
Follow-Up Care for Breast and Colorectal Cancer Across the Globe: Survey Findings From 27 Countries.
Related Articles Follow-Up Care for Breast and Colorectal Cancer Across the Globe: Survey Findings From 27 Countries. JCO Glob Oncol. 2020 Sep;6:1394-1411 Authors: Mollica MA, Mayer DK, Oeffinger KC, Kim Y, Buckenmaier SS, Sivaram S, Muha C, Taib NA, Andritsch E, Asuzu CC, Bochis OV, Diaz S, Trill MD, Garcia PJ, Grassi L, Uchitomi Y, Shaikh AJ, Jefford M, Lee HJ, Johansen C, Luyirika E, Maher EJ, Mallillin MMB, Maniragaba T, Mehnert-Theuerkauf A, Pramesh CS,...
Tue Sep 22, 2020 14:15
Related Articles Safety and Evidence of Off-Label Use of Approved Drugs at the National Cancer Center Hospital in Japan. JCO Oncol Pract. 2020 Sep 21;:OP2000131 Authors: Bun S, Yonemori K, Sunadoi H, Nishigaki R, Noguchi E, Okusaka T, Nishida T, Fujiwara Y Abstract PURPOSE: In Japan, for pharmaceutical products to be covered by public medical insurance, their efficacy and safety must first be confirmed in clinical trials. To our knowledge, this...
Tue Sep 22, 2020 15:50
Crystal Bone: Predicting Short-Term Fracture Risk From Electronic Health Records With Deep Learning.
Related Articles Crystal Bone: Predicting Short-Term Fracture Risk From Electronic Health Records With Deep Learning. J Med Internet Res. 2020 Sep 12;: Authors: Almog YA, Rai A, Zhang P, Moulaison A, Powell R, Mishra A, Weinberg K, Hamilton C, Oates M, McCloskey E, Cummings SR Abstract BACKGROUND: Fractures due to osteoporosis and low bone mass are common and give rise to significant clinical, personal, and economic burden. Even after a fracture...
Tue Sep 22, 2020 14:15
Related Articles HRI depletion cooperates with pharmacologic inducers to elevate fetal hemoglobin and reduce sickle cell formation. Blood Adv. 2020 Sep 22;4(18):4560-4572 Authors: Peslak SA, Khandros E, Huang P, Lan X, Geronimo CL, Grevet JD, Abdulmalik O, Zhang Z, Giardine BM, Keller CA, Shi J, Hardison RC, Blobel GA Abstract Increasing fetal hemoglobin (HbF) provides clinical benefit in patients with sickle cell disease (SCD). We recently...
Tue Sep 22, 2020 14:15
Related Articles USP44 hypermethylation promotes cell proliferation and metastasis in breast cancer. Future Oncol. 2020 Sep 21;: Authors: Chen X, Wu X, Lei W Abstract Aim: The methylation and expression levels of USP44 in breast cancer were investigated and their effects on tumor cells were researched. Materials & Methods: Bioinformatics was employed to identify the target gene from TCGA database. Sodium bisulfite and decitabine were used...
Tue Sep 22, 2020 15:50
Related Articles Impact of reduced-intensity conditioning regimens on outcomes in diffuse large B-cell lymphoma undergoing allogeneic transplantation. Biol Blood Marrow Transplant. 2020 Sep 18;: Authors: Epperla N, Ahn KW, Khanal M, Litovich C, Ahmed S, Ghosh N, Fenske TS, Kharfan-Dabaja MA, Sureda A, Hamadani M Abstract BACKGROUND: Reduced-intensity conditioning (RIC) regimens are frequently used for allogeneic hematopoietic cell transplantation...
Tue Sep 22, 2020 15:50
Related Articles Maternal altitude and risk of low birthweight: A systematic review and meta-analyses. Placenta. 2020 Sep 15;101:124-131 Authors: Yang L, Helbich-Poschacher V, Cao C, Klebermass-Schrehof K, Waldhoer T Abstract BACKGROUND: Previous studies conducted in high altitude regions showed that maternal altitude was associated with low birth weight. The effect size of birth weight reduction is inclusive with unknown effects due to preterm...
Tue Sep 22, 2020 15:50
Related Articles Peptide-functionalized metal-organic framework nanocomposite for ultrasensitive detection of secreted protein acidic and rich in cysteine with practical application. Biosens Bioelectron. 2020 Sep 15;169:112613 Authors: Wu S, Sun Z, Peng Y, Han Y, Li J, Zhu S, Yin Y, Li G Abstract In this work, we have prepared peptide-functionalized metal-organic frameworks (MOFs) as signal-amplifying tags for the detection of secreted protein...
Tue Sep 22, 2020 15:50
Related Articles Tobacco-related cancers in Europe: The scale of the epidemic in 2018. Eur J Cancer. 2020 Sep 18;139:27-36 Authors: Kulhánová I, Forman D, Vignat J, Espina C, Brenner H, Storm HH, Bauld L, Soerjomataram I Abstract BACKGROUND: Tobacco smoking is the major preventable cause of cancer. Despite the longstanding decline in smoking prevalence, lung cancer remains one of the most frequently diagnosed cancers in both sexes. We aimed...
Tue Sep 22, 2020 15:50
Related Articles [The role of the traditional surgical procedures for gastroesophageal reflux disease cannot be ignored]. Zhonghua Wai Ke Za Zhi. 2020 Sep 01;58(9):672-676 Authors: Zhou JH, Tan QY Abstract Gastroesophageal reflux disease (GERD) is a common digestive disease with characteristics of a multitude of pathogenesis, a variety of clinical manifestations and a strong negative impact on physical and mental health of the patients. GERD...
Tue Sep 22, 2020 14:19
Related Articles [The evolution and expectation of surgical options for gastroesophageal reflux disease]. Zhonghua Wai Ke Za Zhi. 2020 Sep 01;58(9):677-682 Authors: Wu JM, Chen D Abstract It has been nearly 70 years since the first attempt of surgical treatment for gastroesophageal reflux disease in Western countries, while in China, it is still in initial stage. Allison first attempted to control gastroesophageal reflux through surgical approach...
Tue Sep 22, 2020 14:19
We aimed to explore the efficacy of orbital radiotherapy (RT) in patients with moderate-to-severe active Graves’ orbitopathy (GO), including long-lasting disease, and to determine the predictive factors associ...
Mon Sep 21, 2020 03:00
Related Articles Comprehensive three-dimensional analysis (CUBIC-kidney) visualizes abnormal renal sympathetic nerves after ischemia/reperfusion injury. Kidney Int. 2019 07;96(1):129-138 Authors: Hasegawa S, Susaki EA, Tanaka T, Komaba H, Wada T, Fukagawa M, Ueda HR, Nangaku M Abstract The sympathetic nervous system is critical in maintaining the homeostasis of renal functions. However, its three-dimensional (3D) structures in the kidney have...
Tue Sep 22, 2020 14:30
Related Articles The impact of EGFR gene polymorphisms on the response and toxicity derived from neoadjuvant chemotherapy for breast cancer. Gland Surg. 2020 Aug;9(4):925-935 Authors: Wang Y, Wu Z, Zhou L, Lu J, Wang Y, Lin Y, Xu S, Ye Y, Peng J, Zhang J, Yin W, Lu J Abstract Background: Neoadjuvant chemotherapy is usually used for treating locally advanced breast cancer. However, not all patients achieve pathologic complete response (pCR)....
Tue Sep 22, 2020 14:30
Related Articles Association of higher axillary pathologic complete response rate with breast pathologic complete response after neoadjuvant chemotherapy. Ann Transl Med. 2020 Aug;8(16):992 Authors: Zhu J, Li J, Fan Z, Wang H, Zhang J, Yin Y, Fu P, Geng C, Jin F, Jiang Z, Liu Z Abstract Background: To investigate the association of axillary pathologic complete response (pCR) rate among breast cancer patients with pCR after neoadjuvant chemotherapy...
Tue Sep 22, 2020 14:30
Related Articles Tripartite motif-containing 35 (TRIM35) is up-regulated in UUO-induced renal fibrosis animal model. Histol Histopathol. 2020 Sep 21;:18255 Authors: Chen Y, Ding Y, Wang LM Abstract Renal fibrosis has been recognized as a serious health threat in the world because of the high cost of treatment and poor prognosis. However, the molecular mechanism of renal fibrosis is still largely unknown. In this study, we aimed at illustrating...
Tue Sep 22, 2020 14:50
Related Articles Association of Autofluorescence-Based Detection of the Parathyroid Glands During Total Thyroidectomy With Postoperative Hypocalcemia Risk: Results of the PARAFLUO Multicenter Randomized Clinical Trial. JAMA Surg. 2020 02 01;155(2):106-112 Authors: Benmiloud F, Godiris-Petit G, Gras R, Gillot JC, Turrin N, Penaranda G, Noullet S, Chéreau N, Gaudart J, Chiche L, Rebaudet S Abstract Importance: Because inadvertent damage of parathyroid...
Tue Sep 22, 2020 14:53
Related Articles Direct Functional Protein Delivery with a Peptide into Neonatal and Adult Mammalian Inner Ear In Vivo. Mol Ther Methods Clin Dev. 2020 Sep 11;18:511-519 Authors: Zhang K, Cheng X, Zhao L, Huang M, Tao Y, Zhang H, Rosenholm JM, Zhuang M, Chen ZY, Chen B, Shu Y Abstract The aim of this study was to study an antimicrobial peptide (AMP), aurein 1.2, which substantially increased protein delivery directly into multiple mammalian...
Tue Sep 22, 2020 14:53
Related Articles Antibody-Based Receptor Targeting Using an Fc-Binding Peptide-Dodecaborate Conjugate and Macropinocytosis Induction for Boron Neutron Capture Therapy. ACS Omega. 2020 Sep 15;5(36):22731-22738 Authors: Nakase I, Aoki A, Sakai Y, Hirase S, Ishimura M, Takatani-Nakase T, Hattori Y, Kirihata M Abstract Boron neutron capture therapy (BNCT) is a radiation method used for cancer therapy. Cellular uptake of boron-10 (10B) atoms induces...
Tue Sep 22, 2020 14:53
Related Articles Synergistic effects of combined treatment with ultrasound-mediated cisplatin-loaded microbubbles and atorvastatin on head and neck cancer. Head Neck. 2020 Sep 21;: Authors: Liao AH, Lin WT, Chen HK, Shih CP, Wang CH, Chu YH Abstract BACKGROUND: Previously, we used ultrasound (US)-mediated cisplatin (CDDP)-loaded microbubbles (CDDP-MBs) to increase intratumoral CDDP level while decreasing systemic cytotoxicity. Statins have shown...
Tue Sep 22, 2020 14:53
Abstract Drugs of abuse, including cocaine, alter the mechanisms underpinning synaptic plasticity, including long‐term potentiation of glutamatergic synapses in the mesolimbic system. These effects are thought to underlie addictive behaviors. In the ventral tegmental area (VTA), glutamatergic synapses also exhibit long‐term depression (LTD), a type of plasticity that weakens synaptic strength. This form of synaptic plasticity is induced by low‐frequency stimulation and mediated by endocannabinoid...
Mon Sep 21, 2020 20:32
The year 2019 was considered to be the first year of cancer genome medicine in Japan, with three gene‐panel tests using next‐generation sequencing (NGS) techniques being introduced into clinical practice. Among the three tests, the Oncomine CDx Target test was approved under the category of regular molecular testing for lung cancer, which meant that this test could be used to select patients for molecularly targeted drugs. Conversely, the other two tests, NCC OncoPanel and FoundationOne CDx, were...
Mon Sep 21, 2020 20:23
Parvovirus B19 infection in pediatrics most commonly causes fifth disease, a mild viral illness. Hematologic manifestations include severe anemia, especially in patients with chronic hemolytic anemias or who are immunocompromised. Because of the shortened life span of erythrocytes in patients with sickle cell disease, parvovirus infection can cause transient aplastic crisis which can be life-threatening. However, leukocytosis and thrombocytosis are rarely seen. We report leukoerythroblastosis as...
Tue Sep 22, 2020 08:50
Related Articles Identification and Analyses of Extra-Cranial and Cranial Rhabdoid Tumor Molecular Subgroups Reveal Tumors with Cytotoxic T Cell Infiltration. Cell Rep. 2019 11 19;29(8):2338-2354.e7 Authors: Chun HE, Johann PD, Milne K, Zapatka M, Buellesbach A, Ishaque N, Iskar M, Erkek S, Wei L, Tessier-Cloutier B, Lever J, Titmuss E, Topham JT, Bowlby R, Chuah E, Mungall KL, Ma Y, Mungall AJ, Moore RA, Taylor MD, Gerhard DS, Jones SJM, Korshunov A, Gessler...
Tue Sep 22, 2020 15:27
Related Articles Utility of copy number variants in the classification of intracranial ependymoma. Cancer Genet. 2020 01;240:66-72 Authors: Evenson M, Cai C, Hucthagowder V, McNulty S, Neidich J, Kulkarni S, Dahiya S Abstract Ependymomas are neuroepithelial tumors that differentiate along the ependymal cell lineage, a lining of the ventricles of the brain and the central canal of the spinal cord. They are rare in adults, but account for around...
Tue Sep 22, 2020 15:27
Related Articles Treatment of Sinonasal Teratocarcinosarcoma: A Systematic Review and Survival Analysis. Am J Rhinol Allergy. 2020 Sep 20;:1945892420959585 Authors: Chapurin N, Totten DJ, Morse JC, Khurram MS, Louis PC, Sinard RJ, Chowdhury NI Abstract BACKGROUND: Sinonasal teratocarcinosarcoma (SNTCS) is a rare malignancy of the anterior skull base with only 127 cases described in the English literature. Given the rarity of this tumor, new...
Tue Sep 22, 2020 15:27
Related Articles Can young vascular neurosurgeons become proficient in microsurgical clip reconstruction in the endovascular era? A Rotterdam cohort spanning two decades with propensity-score matching for complexity. World Neurosurg. 2020 Sep 18;: Authors: Volovici V, Verploegh ISC, Vos JC, Delwel EJ, Bijvoet HWC, van Putten HP, Schouten JW, Avezaat CJJ, Dirven CMF, Dammers R Abstract BACKGROUND: Little is known about the results of young vascular...
Tue Sep 22, 2020 15:27
Related Articles Chasing the rainbow: pleasure, sex-based sociality and consumerism in navigating and exiting the Irish Chemsex scene. Cult Health Sex. 2019 09;21(9):1074-1086 Authors: Van Hout MC, Crowley D, O'Dea S, Clarke S Abstract Club drug use among gay, bisexual and other men who have sex with men is increasingly normalised within sexual contexts and is associated with increased sexual risk behaviours. The term Chemsex is used to describe...
Tue Sep 22, 2020 15:28
Related Articles Weight Loss and Serum Lipids in Overweight and Obese Adults: A Systematic Review and Meta-analysis. J Clin Endocrinol Metab. 2020 Sep 21;: Authors: Hasan B, Nayfeh T, Alzuabi M, Wang Z, Kuchkuntla AR, Prokop LJ, Newman CB, Murad MH, Rajjo TI Abstract BACKGROUND: Excess adipose tissue is associated with an abnormal lipid profile that may improve with weight reduction. In this meta-analysis, we aimed to estimate the magnitude...
Tue Sep 22, 2020 15:29
Related Articles Treatment of Thyroid Dysfunction and Serum Lipids: A Systematic Review and Meta-Analysis. J Clin Endocrinol Metab. 2020 Sep 21;: Authors: Kotwal A, Cortes T, Genere N, Hamidi O, Jasim S, Newman CB, Prokop LJ, Murad MH, Alahdab F Abstract CONTEXT: Hyperthyroidism is associated with low levels of cholesterol and triglycerides, and hypothyroidism is associated with hypercholesterolemia and hypertriglyceridemia. OBJECTIVE:...
Tue Sep 22, 2020 15:29
Related Articles Olfactory Function After Surgical Treatment of CRS: A Comparison of CRS Patients to Healthy Controls. Am J Rhinol Allergy. 2020 Sep 20;:1945892420960671 Authors: Mattos JL, Soler ZM, Schlosser RJ, Mace JC, Alt JA, Ramakrishnan VR, Payne SC, Smith TL, Beswick DM Abstract BACKGROUND: Many patients with chronic rhinosinusitis (CRS) have persistent olfactory dysfunction (OD) following endoscopic sinus surgery (ESS). Few studies...
Tue Sep 22, 2020 15:30
Related Articles Diagnostic Criteria of Recurrent Acute Rhinosinusitis: A Systematic Review. Am J Rhinol Allergy. 2020 Sep 20;:1945892420956871 Authors: Saltagi MZ, Comer BT, Hughes S, Ting JY, Higgins TS Abstract BACKGROUND: RARS is a challenging clinical phenomenon that affects many patients, and diagnostic criteria for this condition are not fully characterized in the literature. OBJECTIVE: To examine diagnostic criteria for...
Tue Sep 22, 2020 15:30
38 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2020/09/22PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Tue Sep 22, 2020 13:36
Related Articles Photogrammetric Three-dimensional Modeling and Printing of Cetacean Skeleton using an Omura's Whale Stranded in Hong Kong Waters as an Example. J Vis Exp. 2020 Sep 03;(163): Authors: Kot BCW, Tsui HCL, Chung TYT, Cheng WW, Mui T, Lo MYL, Yamada TK, Mori K, Brown RAL Abstract The preparation of cetacean, in particular baleen whale, skeletons presents a great challenge due to their high lipid content and uncommon size. Documentation...
Tue Sep 22, 2020 15:41
Related Articles Cryogenic Sample Loading into a Magic Angle Spinning Nuclear Magnetic Resonance Spectrometer that Preserves Cellular Viability. J Vis Exp. 2020 Sep 01;(163): Authors: Ghosh R, Kragelj J, Xiao Y, Frederick KK Abstract Dynamic nuclear polarization (DNP) can dramatically increase the sensitivity of magic angle spinning (MAS) nuclear magnetic resonance (NMR) spectroscopy. These sensitivity gains increase as temperatures decrease...
Tue Sep 22, 2020 15:41
Related Articles Whole Animal Imaging of Drosophila melanogaster using Microcomputed Tomography. J Vis Exp. 2020 Sep 02;(163): Authors: Schoborg TA Abstract Biomedical imaging tools permit investigation of molecular mechanisms across spatial scales, from genes to organisms. Drosophila melanogaster, a well-characterized model organism, has benefited from the use of light and electron microscopy to understand gene function at the level of...
Tue Sep 22, 2020 15:41
Related Articles Two-Dimensional Visualization and Quantification of Labile, Inorganic Plant Nutrients and Contaminants in Soil. J Vis Exp. 2020 Sep 01;(163): Authors: Wagner S, Hoefer C, Prohaska T, Santner J Abstract We describe a method for two-dimensional (2D) visualization and quantification of the distribution of labile (i.e., reversibly adsorbed) inorganic nutrient (e.g., P, Fe, Mn) and contaminant (e.g., As, Cd, Pb) solute species...
Tue Sep 22, 2020 15:41
Related Articles Intracerebroventricular Treatment with Resiniferatoxin and Pain Tests in Mice. J Vis Exp. 2020 Sep 02;(163): Authors: Fukushima A, Fujii M, Ono H Abstract The transient receptor potential vanilloid type 1 (TRPV1), a thermosensitive cation channel, is known to trigger pain in the peripheral nerves. In addition to its peripheral function, its involvement in brain functions has also been suggested. Resiniferatoxin (RTX), an...
Tue Sep 22, 2020 15:41
Related Articles Sheath-Preserving Optic Nerve Transection in Rats to Assess Axon Regeneration and Interventions Targeting the Retinal Ganglion Cell Axon. J Vis Exp. 2020 Sep 06;(163): Authors: Do JL, Allahwerdy S, David RC, Weinreb RN, Welsbie DS Abstract Retinal ganglion cell (RGC) axons converge at the optic nerve head to convey visual information from the retina to the brain. Pathologies such as glaucoma, trauma, and ischemic optic...
Tue Sep 22, 2020 15:41
Related Articles Unraveling the Role of Discrete Areas of the Rat Brain in the Regulation of Ovulation through Reversible Inactivation by Tetrodotoxin Microinjections. J Vis Exp. 2020 Sep 03;(163): Authors: Silva CC, Bolaños-Hurtado M, Juárez-Tapia C, Flores A, Arrieta-Cruz I, Cruz ME, Domínguez R Abstract Many experimental approaches have been used for studying the role of the brain in the regulation of ovulation. Examples include the...
Tue Sep 22, 2020 15:41
Related Articles Electroretinogram Recording for Infants and Children under Anesthesia to Achieve Optimal Dark Adaptation and International Standards. J Vis Exp. 2020 Sep 03;(163): Authors: Lam BL, Mendoza-Santiestaban C, Gonzalez A, Rowaan C, Liu M, Martin J, Gayer S, Figueredo OG, Parel JM Abstract Electroretinogram (ERG) is the only clinical objective test available to assess retinal function. Full-field ERG (ffERG) measures the panretinal...
Tue Sep 22, 2020 15:41
Related Articles A Model Membrane Platform for Reconstituting Mitochondrial Membrane Dynamics. J Vis Exp. 2020 Sep 02;(163): Authors: Ge Y, Boopathy S, Smith A, Chao LH Abstract Mitochondrial dynamics is essential for the organelle's diverse functions and cellular responses. The crowded, spatially complex, mitochondrial membrane is a challenging environment to distinguish regulatory factors. Experimental control of protein and lipid components...
Tue Sep 22, 2020 15:41
Related Articles Chromatographic Fingerprinting by Template Matching for Data Collected by Comprehensive Two-Dimensional Gas Chromatography. J Vis Exp. 2020 Sep 02;(163): Authors: Stilo F, Cordero C, Bicchi C, Peroni D, Tao Q, Reichenbach SE Abstract Data processing and evaluation are critical steps of comprehensive two-dimensional gas chromatography (GCxGC), particularly when coupled to mass spectrometry. The rich information encrypted...
Tue Sep 22, 2020 15:41
Related Articles Delayed Intramyocardial Delivery of Stem Cells after Ischemia Reperfusion Injury in a Murine Model. J Vis Exp. 2020 Sep 03;(163): Authors: Olthoff M, Franchi F, Peterson KM, Paulmurugan R, Rodriguez-Porcel M Abstract There is significant interest in the use of stem cells (SCs) for the recovery of cardiac function in individuals with myocardial injuries. Most commonly, cardiac stem cell therapy is studied by delivering SCs...
Tue Sep 22, 2020 15:41
Related Articles Detergent-Free Decellularization of the Human Pancreas for Soluble Extracellular Matrix (ECM) Production. J Vis Exp. 2020 Sep 04;(163): Authors: Tamburrini R, Chaimov D, Asthana A, Enck K, Muir SM, Aziz JM, Lablanche S, Tubbs E, Tomei AA, Van Dyke M, Soker S, Opara EC, Orlando G Abstract Islet transplantation (ITx) has the potential to become the standard of care in beta cell replacement medicine but its results remain...
Tue Sep 22, 2020 15:41
Related Articles Enabling Real-Time Compensation in Fast Photochemical Oxidations of Proteins for the Determination of Protein Topography Changes. J Vis Exp. 2020 Sep 01;(163): Authors: Misra SK, Sharp JS Abstract Fast photochemical oxidation of proteins (FPOP) is a mass spectrometry-based structural biology technique that probes the solvent-accessible surface area of proteins. This technique relies on the reaction of amino acid side chains...
Tue Sep 22, 2020 15:41
Related Articles Characterizing Exon Skipping Efficiency in DMD Patient Samples in Clinical Trials of Antisense Oligonucleotides. J Vis Exp. 2020 May 07;(159): Authors: Nordin JZ, Mizobe Y, Nakamura H, Komaki H, Takeda S, Aoki Y Abstract Duchenne muscular dystrophy (DMD) is a degenerative muscle disease that causes progressive loss of muscle mass, leading to premature death. The mutations often cause a distorted reading frame and premature...
Tue Sep 22, 2020 15:41
Related Articles Imaging and Quantification of the Area of Fast-Moving Microbubbles Using a High-Speed Camera and Image Analysis. J Vis Exp. 2020 Sep 05;(163): Authors: Vyas N, Mahmud M, Wang QX, Walmsley AD Abstract An experimental and image analysis technique is presented for imaging cavitation bubbles and calculating their area. The high-speed imaging experimental technique and image analysis protocol presented here can also be applied...
Tue Sep 22, 2020 15:41
Related Articles PhysioArt: a teaching tool to motivate students to learn physiology. Adv Physiol Educ. 2020 Dec 01;44(4):564-569 Authors: Flôr AFL, Fernandes Costa F, Lima Garcia JM, Braga VA, Cruz JC Abstract Learning physiology is challenging for students. The nature of the discipline, which includes many complex mechanisms, makes the subject complicated. Furthermore, the length of the textbooks and the usual multiple-choice tests, which...
Tue Sep 22, 2020 15:42
Related Articles Smartphone-assisted experimentation as a didactic strategy to maintain practical lessons in remote education: alternatives for physiology education during the COVID-19 pandemic. Adv Physiol Educ. 2020 Dec 01;44(4):579-586 Authors: Lellis-Santos C, Abdulkader F Abstract Online and distance education may be dismissed by educators who argue that these methods are not equivalent to traditional face-to-face education due to the lack...
Tue Sep 22, 2020 15:42
Related Articles Redesign and process of reforming an existing undergraduate Nutritional Sciences program. Adv Physiol Educ. 2020 Dec 01;44(4):570-578 Authors: Becker TB, Lucas J, Li W, Fenton JI Abstract Due to current and upcoming needs in the discipline and accreditation, the Nutritional Sciences faculty at a major university reformed their curriculum using backward design. As part of this process, they developed new learning outcomes that...
Tue Sep 22, 2020 15:42
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου