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Brain SciencesBrain Sciences, Vol. 10, Pages 68... Transplantation of a 3D Bioprinted Patch in a Mur... Economic evaluation of adjuvant trastuzumab thera... Small bowel obstruction after caesarean section: ... Progression of Fetal Brain Lesions in Tuberous Sc... Development of a Tongue Immobilization Device Usi... A phase I/II study of docetaxel in combination w... Description of a giant hypothalamic hamartoma as... Effect of increasing occlusal vertical dimension ... Clinical effect of an active transcutaneous bone-... Prognostic and Predictive Value of Tumor-Infiltra... Rare High level MYC amplification in B-cell lymphomas: ... Rare benign and malignant testicular lesions: hist... Acute abdominal pain in an adolescent girl with an... Conservative treatment in early stage endometrial ... Risk factors and molecular characterization of pen... Extrinsic compression of the heart consequent to i... Anesthetic Management of an Adult Patient With Hya... Epistaxis as an initial symptom of brown tumor in ... Space-Making Particle Therapy with Surgical Spacer... classification of amyloid deposits. Serrated polyposis syndrome (SPS) is a complex dis... Management of sporadic vestibular schwannoma with ... Novel therapeutic targets in salivary duct carcino... Mitomycin and 5-fluorouracil for second-line treat... Ossifying fibroma arising from the zygomatic arch:... Tumor pH-Responsive Albumin/Polyaniline Assemblies... MYCN amplification drives an aggressive form of sp... Surgical Intervention for Refractory Donor-Site Se... Suspected Familial or Sporadic Nasopharyngeal Carc... regnancy epulis with aggressive bone loss mimickin... Xeroderma pigmentosum: sensorineural deafness, men... Oncology Genes Biology CA Chaperone‐mediated autophagy receptor modulates tu... Prognostic impact of CRTC1/3‐MAML2 fusions in sali... Peripheral chemoresponsiveness during exercise in ... TMS over the posterior cerebellum modulates motor ... Iatrogenic Laryngotracheal Stenosis and Type II Di... DNA mismatch repair protein deficiency in ampullar... Decline in circulating viral and human tumor marke... Spectrum and frequencies of non GJB2 gene mutation... Premature ageing disorders Full‐Crown Versus Endocrown Approach Expanding the allergen repertoire of salmon and ca... Bartter syndrome is characterized by extreme hypok... OSA skipped-level lumbar disc herniation.....IntraSPIN... changes in the levels of catecholamines and blood ... Sleep Disordered Breathing ... supplemental O2 red... cardiometabolic contributors to brain health. Slow-wave sleep is associated with incident hypert... Regular use of ibuprofen reduces rat penile prosta... Identifying Three Otopathologies in Humans....: 1)... Changes in audiometric threshold and frequency sel... Positional Installation of Intranasal Corticostero... Bilateral Hearing Loss and Unilateral Cochlear Oss... Endoscopic Cricopharyngeal Myotomy With Primary Cl... recurrent respiratory papillomatosis (RRP) and ben... First case of Ethmoid Metastasis From an Induced O... microRNA-216b enhances cisplatin-induced apoptosis... Congenital Adrenal Hyperplasia Due to 21-Hydroxyla... Dapagliflozin in Patients with Chronic Kidney Dise... Association Between Prescribed Ibuprofen and Sever... Food Immunotherapy: Choosing Wisely Pediatric Intracapsular Tonsillectomy Solitary ulcero‐necrotic papule on the eyelid Adjuvant treatment with secukinumab induced long t... The neuropharmacology of cannabinoid receptor liga... Ascending aorta pseudoaneurysm simulating mediasti... Autophagy regulates levels of tumor suppressor enz... SCTR hypermethylation is a diagnostic biomarker in... NutrientsNutrients, Vol. 12, Pages 2961: The Ef... MoleculesMolecules, Vol. 25, Pages 4437: The Pot... Journal of Clinical MedicineJCM, Vol. 9, Pages ... International Journal of Environmental Research... DiagnosticsDiagnostics, Vol. 10, Pages 751: Myoc... AntibioticsAntibiotics, Vol. 9, Pages 647: A Co...
High level MYC amplification in B-cell lymphomas: is it a marker of aggressive disease?: Related ArticlesHigh level MYC amplification in B-cell lymphomas: is it a marker of aggressive disease?Blood Cancer J. 2020 01 13;10(1):5Authors: Pophali PA, Marinelli LM, Ketterling RP, Meyer RG, McPhail ED, Kurtin PJ, Mwangi R, Maurer MJ, Habermann T, King RLAbstract While MYC translocations in B-cell lymphoma (BCL) have been extensively studied, the significance of MYC amplification (MYC amp) is...
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Rare benign and malignant testicular lesions: histopathology and management.: Related ArticlesRare benign and malignant testicular lesions: histopathology and management.Curr Opin Urol. 2020 03;30(2):235-244Authors: Kern SQ, Speir RW, Akgul M, Cary CAbstract PURPOSE OF REVIEW: The presence of vascular solid tumors within the testicle is considered to be malignant until proven otherwise. However, it is prudent for clinicians to be aware of rare benign and malignant intratesticular lesions...
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Acute abdominal pain in an adolescent girl with an ovarian yolk sac tumor.: Related ArticlesAcute abdominal pain in an adolescent girl with an ovarian yolk sac tumor.Acta Biomed. 2019 12 23;90(4):599-602Authors: Stefanelli E, Talarico V, Scavone M, Carboni E, Stranieri G, Galati MC, Salerno D, Raiola GAbstract Yolk sac tumor (YST) is a rare tumor that usually occurs in the first two decades of life. It is considered the second most common malignant germ cell tumor of the ovary, characterized...
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Conservative treatment in early stage endometrial cancer: a review.: Related ArticlesConservative treatment in early stage endometrial cancer: a review.Acta Biomed. 2019 12 23;90(4):405-410Authors: Trojano G, Olivieri C, Tinelli R, Damiani GR, Pellegrino A, Cicinelli EAbstract Endometrial Cancer (EC) is the commonest gynecological cancer and its incidence is increasing. The diagnosis of endometrial carcinoma in young women of childbearing age is rare. Indeed, only 4% of patients with endometrial...
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Risk factors and molecular characterization of penile cancer: impact on prognosis and potential targets for systemic therapy.: Related ArticlesRisk factors and molecular characterization of penile cancer: impact on prognosis and potential targets for systemic therapy.Curr Opin Urol. 2020 03;30(2):202-207Authors: Thomas A, Vanthoor J, Vos G, Tsaur I, Albersen M, collaboration with the European Reference Network for rare urogenital diseases and complex conditions (eUROGEN)Abstract PURPOSE...
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An Unusual Cause of Intraoperative Hemodynamic Instability Complicating Elective Mastectomy With Immediate Free Flap Reconstruction: A Case Report.: Related ArticlesAn Unusual Cause of Intraoperative Hemodynamic Instability Complicating Elective Mastectomy With Immediate Free Flap Reconstruction: A Case Report.A A Pract. 2020 Feb 15;14(4):102-105Authors: Young B, Chamos C, Fitzwilliams B, Desai NAbstract Extrinsic compression of the heart consequent to intrapleural fluid is a rare cause...
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Anesthetic Management of an Adult Patient With Hyaline Fibromatosis Syndrome Undergoing Laparoscopic Colectomy: A Case Report.: Related ArticlesAnesthetic Management of an Adult Patient With Hyaline Fibromatosis Syndrome Undergoing Laparoscopic Colectomy: A Case Report.A A Pract. 2020 Feb 01;14(3):87-89Authors: Yoshikawa M, Shinomura T, Kishimoto K, Uga HAbstract Hyaline fibromatosis syndrome (HFS) is a rare autosomal recessive disorder characterized by hyaline fibrous depositions in the...
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Epistaxis as an initial symptom of brown tumor in hard palate: a rare case report and review.: Related ArticlesEpistaxis as an initial symptom of brown tumor in hard palate: a rare case report and review.Laryngorhinootologie. 2020 03;99(3):168-172Authors: Chen X, Yan X, Zhao H, Zhang XY, Liu P, Jiang Y, Ju JPMID: 31779031 [PubMed - indexed for MEDLINE]
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Space-Making Particle Therapy with Surgical Spacer Placement in Patients with Sacral Chordoma.: Related ArticlesSpace-Making Particle Therapy with Surgical Spacer Placement in Patients with Sacral Chordoma.J Am Coll Surg. 2020 02;230(2):207-215Authors: Tsugawa D, Komatsu S, Demizu Y, Sulaiman NS, Suga M, Kido M, Toyama H, Okimoto T, Sasaki R, Fukumoto TAbstract BACKGROUND: Sacral chordomas are rare malignant bone tumors and are often very large for complete resection. Particle therapy for...
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Immunoelectron microscopy and mass spectrometry for classification of amyloid deposits.: Related ArticlesImmunoelectron microscopy and mass spectrometry for classification of amyloid deposits.Amyloid. 2020 Mar;27(1):59-66Authors: Abildgaard N, Rojek AM, Møller HE, Palstrøm NB, Nyvold CG, Rasmussen LM, Hansen CT, Beck HC, Marcussen NAbstract Amyloidosis is a shared name for several rare, complex and serious diseases caused by extra-cellular deposits of different misfolded proteins. Accurate...
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Identification of a Novel Candidate Gene for Serrated Polyposis Syndrome Germline Predisposition by Performing Linkage Analysis Combined With Whole-Exome Sequencing.: Related ArticlesIdentification of a Novel Candidate Gene for Serrated Polyposis Syndrome Germline Predisposition by Performing Linkage Analysis Combined With Whole-Exome Sequencing.Clin Transl Gastroenterol. 2019 10;10(10):e00100Authors: Toma C, Díaz-Gay M, Soares de Lima Y, Arnau-Collell C, Franch-Expósito S, Muñoz J, Overs B, Bonjoch...
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Management of sporadic vestibular schwannoma with contralateral nonserviceable hearing.: Related ArticlesManagement of sporadic vestibular schwannoma with contralateral nonserviceable hearing.Laryngoscope. 2020 06;130(6):E407-E415Authors: Jia H, Nguyen Y, De Seta D, Hochet B, Smail M, Bernardeschi D, Wu H, Mosnier I, Kalamarides M, Sterkers OAbstract OBJECTIVES/HYPOTHESIS: To outline a possible decision-making process for sporadic vestibular schwannoma (VS) with contralateral nonserviceable...
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Novel therapeutic targets in salivary duct carcinoma uncovered by comprehensive molecular profiling.
Novel therapeutic targets in salivary duct carcinoma uncovered by comprehensive molecular profiling.: Related ArticlesNovel therapeutic targets in salivary duct carcinoma uncovered by comprehensive molecular profiling.Cancer Med. 2019 12;8(17):7322-7329Authors: Gargano SM, Senarathne W, Feldman R, Florento E, Stafford P, Swensen J, Vranic S, Gatalica ZAbstract Salivary duct carcinoma (SDC) is a rare, aggressive salivary gland malignancy, which often presents at an advanced stage. A proportion...
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Mitomycin and 5-fluorouracil for second-line treatment of metastatic squamous cell carcinomas of the anal canal.: Related ArticlesMitomycin and 5-fluorouracil for second-line treatment of metastatic squamous cell carcinomas of the anal canal.Cancer Med. 2019 11;8(16):6853-6859Authors: Saint A, Evesque L, Falk AT, Cavaglione G, Montagne L, Benezery K, Francois EAbstract BACKGROUND: Metastatic squamous cell carcinomas (SCC) of the anal canal are rare and there is no international consensus...
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Ossifying fibroma arising from the zygomatic arch: A case report.: Related ArticlesOssifying fibroma arising from the zygomatic arch: A case report.J Stomatol Oral Maxillofac Surg. 2020 Jun;121(3):288-291Authors: Uesugi A, Mochida K, Harada H, Imai HAbstract INTRODUCTION: Ossifying fibroma (OF) is a rare type of tumor characterized by fibrous tissue proliferation with cementum- or bone-like hard tissue formation. Since its first report by Montgomery in 1927, several cases of OF have been...
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Tumor pH-Responsive Albumin/Polyaniline Assemblies for Amplified Photoacoustic Imaging and Augmented Photothermal Therapy.: Related ArticlesTumor pH-Responsive Albumin/Polyaniline Assemblies for Amplified Photoacoustic Imaging and Augmented Photothermal Therapy.Small. 2019 10;15(42):e1902926Authors: Tian Q, Li Y, Jiang S, An L, Lin J, Wu H, Huang P, Yang SAbstract Tumor-microenvironment-responsive theranostics have great potential for precision diagnosis and effective treatment of cancer....
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MYCN amplification drives an aggressive form of spinal ependymoma.: Related ArticlesMYCN amplification drives an aggressive form of spinal ependymoma.Acta Neuropathol. 2019 12;138(6):1075-1089Authors: Ghasemi DR, Sill M, Okonechnikov K, Korshunov A, Yip S, Schutz PW, Scheie D, Kruse A, Harter PN, Kastelan M, Wagner M, Hartmann C, Benzel J, Maass KK, Khasraw M, Sträter R, Thomas C, Paulus W, Kratz CP, Witt H, Kawauchi D, Herold-Mende C, Sahm F, Brandner S, Kool M, Jones DTW, von Deimling A, Pfister...
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Surgical Intervention for Refractory Donor-Site Seroma After Immediate Breast Reconstruction with Latissimus Dorsi Flap.: Related ArticlesSurgical Intervention for Refractory Donor-Site Seroma After Immediate Breast Reconstruction with Latissimus Dorsi Flap.Aesthetic Plast Surg. 2019 12;43(6):1515-1522Authors: Lee JS, Hong HK, Kim JS, Choi DH, Lee JW, Lee J, Park HY, Yang JDAbstract Donor-site seroma persisting for > 3 weeks is the most common complication of latissimus dorsi (LD) flaps...
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Evaluation of Rare and Common Variants from Suspected Familial or Sporadic Nasopharyngeal Carcinoma (NPC) Susceptibility Genes in Sporadic NPC.: Related ArticlesEvaluation of Rare and Common Variants from Suspected Familial or Sporadic Nasopharyngeal Carcinoma (NPC) Susceptibility Genes in Sporadic NPC.Cancer Epidemiol Biomarkers Prev. 2019 10;28(10):1682-1686Authors: Liu Z, Goldstein AM, Hsu WL, Yu KJ, Chien YC, Ko JY, Jian JJ, Tsou YA, Leu YS, Liao LJ, Chang YL, Wang CP, Wu JS, Hua CH, Lee JC,...
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A puzzling pregnancy epulis with aggressive bone loss mimicking malignant neoplasm: A case report.: Related ArticlesA puzzling pregnancy epulis with aggressive bone loss mimicking malignant neoplasm: A case report.J Stomatol Oral Maxillofac Surg. 2020 Jun;121(3):312-316Authors: Ye C, You M, Cheng G, Zhao L, Huang P, Tang J, Chen Y, Wang XAbstract Epulis is a benign tumor, rarely involves aggressive alveolar bone resorption. This study reported a rare case of rapid growth of pregnancy epulis...
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Xeroderma pigmentosum: overview of pharmacology and novel therapeutic strategies for neurological symptoms.: Related ArticlesXeroderma pigmentosum: overview of pharmacology and novel therapeutic strategies for neurological symptoms.Br J Pharmacol. 2019 11;176(22):4293-4301Authors: Abeti R, Zeitlberger A, Peelo C, Fassihi H, Sarkany RPE, Lehmann AR, Giunti PAbstract Xeroderma pigmentosum (XP) encompasses a group of rare diseases characterized in most cases by malfunction of nucleotide excision...
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Review Cancer Epidemiol Biomarkers Prev. 2019 Oct;28(10):1563-1579. doi: 10.1158/1055-9965.EPI-19-0221.Cancer Progress and Priorities: Lung CancerMatthew B Schabath 1 2, Michele L Cote 3 4Affiliations expandPMID: 31575553 PMCID: PMC6777859 DOI: 10.1158/1055-9965.EPI-19-0221Free PMC articleAbstractIn the United States, lung cancer is the second most common diagnosed cancer and the leading cause of cancer-related death. Though tobacco smoking is the major risk factor accounting for 80 to 90% of all...
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Patient with an autosomal‐recessive MBTPS1‐linked phenotype and clinical features of Silver–Russell syndromeAbstract Pathogenic variants in the MBTPS1 gene encoding the Site 1 protease have been described so far only in one growth retarded patients with skeletal deformities, large ears, a triangular face reminiscent to Silver–Russell syndrome (SRS), and elevated blood lysosomal enzymes. We now report on the identification of a second adult patient homozygous for one of the two published pathogenic...
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Highly replicated evolution of parapatric ecotypes [NEW RESULTS]Parallel evolution of ecotypes occurs when selection independently drives the evolution of similar traits across similar environments. The multiple origin of ecotypes is often inferred on the basis of a phylogeny which clusters populations according to geographic location and not by the environment they occupy. However, the use of phylogenies to infer parallel evolution in closely related populations is problematic due to the potential...
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Prognostic impact of CRTC1/3‐MAML2 fusions in salivary gland mucoepidermoid carcinoma: A multiinstitutional retrospective studyDebate exists as to whether CRTC1/3‐MAML2 fusions have a prognostic significance in salivary mucoepidermoid carcinoma (MEC). We undertook a multiinstitutional study including 153 MEC cases, and found that the fusions were an excellent biomarker for better overall survival in the total and advanced‐stage MEC cohorts. Abstract Mucoepidermoid carcinoma (MEC) is rare, but the...
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Chaperone‐mediated autophagy receptor modulates tumor growth and chemoresistance in non–small cell lung cancer: Lysosome‐associated membrane protein type 2a (LAMP2A) is the key receptor protein of chaperone‐mediated autophagy (CMA). Downregulation of LAMP2A leads to CMA blockade. Our discoveries suggest that LAMP2A is involved in the regulation of cancer malignant phenotypes through CMA modulation and represents a promising new target against chemoresistant non–small cell lung cancer (NSCLC).AbstractChaperone‐mediated...
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Prognostic impact of CRTC1/3‐MAML2 fusions in salivary gland mucoepidermoid carcinoma: A multiinstitutional retrospective study: Debate exists as to whether CRTC1/3‐MAML2 fusions have a prognostic significance in salivary mucoepidermoid carcinoma (MEC). We undertook a multiinstitutional study including 153 MEC cases, and found that the fusions were an excellent biomarker for better overall survival in the total and advanced‐stage MEC cohorts.AbstractMucoepidermoid carcinoma (MEC) is rare, but the...
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Peripheral chemoresponsiveness during exercise in male athletes with exercise‐induced arterial hypoxaemia: New FindingsWhat is the central question of this study?Do highly trained male endurance athletes who develop exercise‐induced arterial hypoxaemia (EIAH) demonstrate reduced peripheral chemoresponsiveness during exercise?What is the main finding and its importance?Those with the lowest arterial saturation during exercise have a smaller ventilatory response to hypercapnia during exercise. There...
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TMS over the posterior cerebellum modulates motor cortical excitability in response to facial emotional expressions: Evidence suggests that the posterior cerebellum is involved in emotional processing. We assessed whether the activity of the posterior cerebellum influences the modulation of motor cortical excitability in response to emotional stimuli. We found that inhibiting activity in the left posterior cerebellum via 1 Hz rTMS led to a reduction in the amplitude of MEPs recorded from the contralateral...
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Characterization of Fibroblasts in Latrogenic Laryngotracheal Stenosis and Type II Diabetes Mellitus: ObjectivesIatrogenic laryngotracheal stenosis (iLTS) is the pathological narrowing of the glottis, subglottis, and/or trachea due to scar tissue. Patients with type 2 diabetes mellitus (T2DM) are over 8 times more likely to develop iLTS and represent 26% to 53% of all iLTS patients. In this investigation, we compared iLTS scar‐derived fibroblasts in patients with and without T2DM.Study DesignControlled...
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Frequency and clinicopathologic associations of DNA mismatch repair protein deficiency in ampullary carcinoma: Routine testing is indicated: BackgroundThe significance of DNA mismatch repair (MMR) deficiency in ampullary cancers (ACs) has not been established.MethodsIn total, 127 ACs with invasive carcinomas measuring ≥3 mmthat had adequate tissue were analyzed immunohistochemically.ResultsMMR loss was detected in 18% of ACs (higher than in colorectal cancers). Twelve tumors with MLH1‐PMS2 loss were...
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Decline in circulating viral and human tumor markers after resection of head and neck carcinoma: AbstractBackgroundDNA sequencing panels can simultaneously quantify human and viral tumor markers in blood. We explored changes in levels of plasma tumor markers following surgical resection of head and neck carcinoma.MethodsIn preresection and postresection plasmas, targeted DNA sequencing quantified variants in 28 human cancer genes and levels of oncogenic pathogens (human papillomavirus [HPV], Epstein‐Barr...
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Spectrum and frequencies of non GJB2 gene mutations in Czech patients with early non‐syndromic hearing loss detected by NGS gene panel and WES: AbstractNon‐syndromic autosomal recessive hearing loss is an extremely heterogeneous disease caused by mutations in more than 80 genes. We examined Czech patients with early/prelingual non‐syndromic, presumably genetic hearing loss (NSHL) without known cause after GJB2 gene testing. Four hundred and twenty one unrelated patients were examined for STRC gene...
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Premature ageing disorders – a clinical and genetic compendium: AbstractProgeroid disorders make up a heterogeneous group of very rare hereditary diseases characterized by clinical signs that often mimic physiological ageing in a premature manner. Apart from Hutchinson‐Gilford progeria syndrome, one of the best‐investigated progeroid disorders, a wide spectrum of other premature ageing phenotypes exist, which differ significantly in their clinical presentation and molecular pathogenesis. NGS‐based...
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Full‐Crown Versus Endocrown Approach: A 3D‐Analysis of Both Restorations and the Effect of Ferrule and Restoration Material: AbstractPurposeTo assess stress distribution in full‐crowns with a composite buildup and endocrowns under axial or oblique loads, both with different ferrules (1 or 2 mm) and ceramic materials (glass ceramic or hybrid ceramic).Materials and MethodsSixteen models were analyzed with finite element analysis. No‐separation contacts were considered between restoration/resin cement...
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Expanding the allergen repertoire of salmon and catfish: AbstractBackgroundDiagnostic tests for fish allergy are hampered by the large number of under‐investigated fish species. Four salmon allergens are well‐characterized and registered with the WHO/IUIS while no catfish allergens have been described so far. In 2008, freshwater‐cultured catfish production surpassed that of salmon, the globally most‐cultured marine species. We aimed to identify, quantify and compare all IgE‐binding proteins in salmon...
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Bartter syndrome with long-term follow-up: a case report: Journal of International Medical Research, Volume 48, Issue 8, August 2020. Bartter syndrome is a rare inherited disease caused by CLCNKB mutation, which results in inactivation of the chloride channel Kb protein. Bartter syndrome is characterized by extreme hypokalemia, hypochloremia, metabolic alkalosis, hyperrenin-induced angiotensinemia, hyperaldosteronemia, and normal blood pressure. We herein report a case of Bartter syndrome that manifested...
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Modified reposition pharyngoplasty for OSAS treatment: How we do it and our results.Related Articles Modified reposition pharyngoplasty for OSAS treatment: How we do it and our results. Acta Otorrinolaringol Esp. 2020 Aug 24;: Authors: Carrasco Llatas M, Valenzuela Gras M, Martínez Ruiz de Apodaca P, Dalmau Galofre J Abstract INTRODUCTION AND PURPOSES: The relevance of the lateral pharyngeal walls in the collapse of the upper airway in obstructive sleep apnea patients has been revealed in the last...
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New combination of IntraSPINE device and posterior lumbar interbody fusion for rare skipped-level lumbar disc herniation: a case report and literature review: Journal of International Medical Research, Volume 48, Issue 8, August 2020. Posterior lumbar interbody fusion is an open surgical technique that has been widely used for the treatment of degenerative lumbar disease. However, traditional lumbar spinal fusion, especially long-segment fusion surgery, is associated with several complications. The...
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Meta-analysis of changes in the levels of catecholamines and blood pressure with continuous positive airway pressure therapy in obstructive sleep apnea.: Related ArticlesMeta-analysis of changes in the levels of catecholamines and blood pressure with continuous positive airway pressure therapy in obstructive sleep apnea.J Clin Hypertens (Greenwich). 2020 Sep 24;:Authors: Green M, Ken-Dror G, Fluck D, Sada C, Sharma P, Fry CH, Han TSAbstract Stress from obstructive sleep apnea (OSA) stimulates...
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Amelioration of Sleep Disordered Breathing with Supplemental Oxygen in Older Adults.: Related ArticlesAmelioration of Sleep Disordered Breathing with Supplemental Oxygen in Older Adults.J Appl Physiol (1985). 2020 Sep 24;:Authors: Rastogi R, Badr MS, Ahmed A, Chowdhuri SAbstract Elderly adults demonstrate increased propensity for breathing instability during sleep compared with younger adults and this may contribute to increased prevalence of sleep disordered breathing (SDB) in this population....
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Insomnia with objective short sleep duration is associated with cognitive impairment: a first look at cardiometabolic contributors to brain health.: Related ArticlesInsomnia with objective short sleep duration is associated with cognitive impairment: a first look at cardiometabolic contributors to brain health.Sleep. 2020 Sep 24;:Authors: Fernandez-Mendoza J, He F, Puzino K, Amatrudo G, Calhoun S, Liao D, Vgontzas AN, Bixler EAbstract STUDY OBJECTIVES: Insomnia with objective short sleep...
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Slow-wave sleep is associated with incident hypertension in patients with obstructive sleep apnea: a cross-sectional study.: Related ArticlesSlow-wave sleep is associated with incident hypertension in patients with obstructive sleep apnea: a cross-sectional study.J Int Med Res. 2020 Sep;48(9):300060520954682Authors: Zhang J, Zhuang Y, Wan NS, Tang X, Zhou W, Si L, Wang Y, Chen BY, Cao JAbstract OBJECTIVE: This study aimed to examine the association between slow-wave sleep ([SWS] N3 stage)...
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Regular use of ibuprofen reduces rat penile prostaglandins and induces cavernosal fibrosis.: Related ArticlesRegular use of ibuprofen reduces rat penile prostaglandins and induces cavernosal fibrosis.Drug Chem Toxicol. 2020 Sep 23;:1-6Authors: Elkamshoushi AA, Hassaan P, Nabil I, Ossama H, Omar SSAbstract Ibuprofen is a commonly used non-steroidal anti-inflammatory drug that is noted for its favorable safety profile. It exerts its therapeutic effect through inhibition of prostaglandin (PG)...
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Identifying Three Otopathologies in Humans: Publication date: Available online 24 September 2020Source: Hearing ResearchAuthor(s): Mark A ParkerHighlights•Persons with thresholds within normal limits may exhibit OHC dysfunction or auditory nerve dysfunction•Operationally defined cochlear synaptopathy is relatively common in adults•Persons with mild or greater hearing loss may exhibit cochlear untuningAbstractObjectives: Hearing-in-noise (HIN) is a primary complaint of both the hearing impaired and...
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Changes in audiometric threshold and frequency selectivity correlate with cochlear histopathology in macaque monkeys with permanent noise-induced hearing loss: Publication date: Available online 24 September 2020Source: Hearing ResearchAuthor(s): Jane A. Burton, Chase A. Mackey, Kaitlyn S. MacDonald, Troy A. Hackett, Ramnarayan RamachandranAuthor links open overlay panelJane A.BurtonaChase A.MackeyaKaitlyn S.MacDonaldbTroy A.HackettbRamnarayanRamachandranbaNeuroscience Graduate Program, Vanderbilt...
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Positional Installation of Intranasal Corticosteroids in the Treatment of Chronic Rhinosinusitis: A Systematic Review of the Literature.: Related ArticlesPositional Installation of Intranasal Corticosteroids in the Treatment of Chronic Rhinosinusitis: A Systematic Review of the Literature.Ear Nose Throat J. 2020 Sep 24;:145561320961004Authors: Cummings EL, Fassas SN, Sykes KJ, Sisson A, Chiu AG, Fox MGAbstract OBJECTIVES: First-line treatment of chronic rhinosinusitis includes topical corticosteroids...
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Bilateral Hearing Loss and Unilateral Cochlear Ossification in a Patient With Chronic Myelogenous Leukemia.: Related ArticlesBilateral Hearing Loss and Unilateral Cochlear Ossification in a Patient With Chronic Myelogenous Leukemia.Ear Nose Throat J. 2020 Sep 24;:145561320961073Authors: Zeng X, Lin Z, Han X, Li J, Zhang P, Gou L, Xu JAbstract Bilateral sensorineural deafness and unilateral cochlear ossification have rarely been described in patients with chronic myeloid leukemia (CML)....
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Swallowing Outcomes in 7 Patients Following Endoscopic Cricopharyngeal Myotomy With Primary Closure.: Related ArticlesSwallowing Outcomes in 7 Patients Following Endoscopic Cricopharyngeal Myotomy With Primary Closure.Ear Nose Throat J. 2020 Sep 24;:145561320959569Authors: Williamson A, Scholfield D, Awad ZAbstract Cricopharyngeal spasm and pharyngeal pouch can result in severe dysphagia symptoms that can have a significant impact on a patient's quality of life. Several surgical interventions...
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Applications of Office-Based 445 nm Blue Laser Transnasal Flexible Laser Surgery: A Case Series and Review of Practice.: Related ArticlesApplications of Office-Based 445 nm Blue Laser Transnasal Flexible Laser Surgery: A Case Series and Review of Practice.Ear Nose Throat J. 2020 Sep 24;:145561320960544Authors: Miller BJ, Abdelhamid A, Karagama YAbstract BACKGROUND: The recent introduction of 445 nm blue laser to office-based laryngology presents potential advantages. These include a desirable...
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First case of Ethmoid Metastasis From an Induced Oropharyngeal Squamous Cell Carcinoma HPV, Interest of the P16 as a Diagnosis Aid.: Related ArticlesFirst case of Ethmoid Metastasis From an Induced Oropharyngeal Squamous Cell Carcinoma HPV, Interest of the P16 as a Diagnosis Aid.Ear Nose Throat J. 2020 Sep 24;:145561320955121Authors: Steffens Y, Mat Q, Beatse V, Meert N, Nagy N, Ichou JA, Duterme JPAbstract We describe the first case of ethmoid metastasis from an oropharyngeal human papillomavirus-induced...
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microRNA-216b enhances cisplatin-induced apoptosis in osteosarcoma MG63 and SaOS-2 cells by binding to JMJD2C and regulating the HIF1α/HES1 signaling axis: Although cisplatin-based chemotherapy represents the standard regimen for osteosarcoma (OS), OS patients often exhibit treatment failure and poor prognosis due to chemoresistance to cisplatin. Emerging researc...
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Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency: Congenital adrenal hyperplasia (CAH) — one of the most common autosomal recessive disorders — is potentially life-threatening in its classic (severe) form and may be asymptomatic or cause female infertility in its nonclassic (mild) form. The most common type of CAH is 21-hydroxylase deficiency; for…
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Dapagliflozin in Patients with Chronic Kidney Disease: Hiddo J.L. Heerspink, Ph.D., Bergur V. Stefánsson, M.D., Ricardo Correa-Rotter, M.D., Glenn M. Chertow, M.D., Tom Greene, Ph.D., Fan-Fan Hou, M.D., Johannes F.E. Mann, M.D., John J.V. McMurray, M.D., Magnus Lindberg, M.Sc., Peter Rossing, M.D., C. David Sjöström, M.D., Roberto D. Toto, M.D., et al., for the DAPA-CKD Trial Committees and Investigators*AbstractBACKGROUNDPatients with chronic kidney disease have a high risk of adverse kidney...
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Association Between Prescribed Ibuprofen and Severe COVID‐19 Infection: A Nationwide Register‐Based Cohort Study: AbstractRecommendations regarding ibuprofen use in relation to coronavirus disease 2019 (COVID‐19) have been conflicting. We examined risk of severe COVID‐19 between ibuprofen‐prescribed and non‐ibuprofen COVID‐19 patients in a nationwide register‐based study of COVID‐19 patients in Denmark between end of February 2020 and May 16, 2020. Patients with heart failure (n=208), <30 years...
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Food Immunotherapy: Choosing Wisely: AbstractFood allergies are common 1,2 and as practicing physicians, we regularly see food‐allergy sufferers in our clinics. We also find them in schools and classrooms, sometimes within our close family and friends' environment. The effect that food allergies have on the individual and their family is significant. All aspects of daily life can be affected, including physical, psychological and social interactions, ultimately impacting on quality of life 3 4 5....
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Current Status and Future Trends: Pediatric Intracapsular Tonsillectomy in the United States: Objectives1) To assess the current status of pediatric intracapsular tonsillectomy in the United States, and 2) To apply lessons from the scientific literature and adoption of surgical innovation to predict future trends in pediatric intracapsular tonsillectomy.MethodsThis was a cross‐sectional survey study and literature review. An anonymous survey was sent to all members of the American Society of Pediatric...
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Adjuvant treatment with secukinumab induced long term remission in a patient with severe bullous pemphigoid:
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The neuropharmacology of cannabinoid receptor ligands in central signaling pathways: AbstractThe endocannabinoid system is a complex neuronal system involved in a number of biological functions, like attention, anxiety, mood, memory, appetite, reward and immune responses. It is at the centre of scientific interest, which is driven by therapeutic promise of certain cannabinoid ligands and the changing legalization of herbal cannabis in many countries. The endocannabinoid system is a modulatory system,...
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Ascending aorta pseudoaneurysm simulating mediastinal lymphoma in computed tomography, a possible diagnostic error: a case report: An ascending aortic pseudoaneurysm is a severe and rare complication following cardiothoracic surgery. This case report demonstrates its possible misinterpretation and the consequent importance of multidiscipl...
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SCTR hypermethylation is a diagnostic biomarker in colorectal cancer: AbstractDiagnostic markers for both colorectal cancer (CRC) and its precursor lesions are lacking. Although aberrant methylation of SCTR gene was observed in CRC, the diagnostic performance has not been evaluated. Therefore, this study aimed to assess and verify the diagnostic value of SCTR methylation of CRC and its precursor lesions through integrating the largest methylation data. The diagnostic performance of SCTR methylation...
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NutrientsNutrients, Vol. 12, Pages 2961: The Effects of Long-Term Magnesium Creatine Chelate Supplementation on Repeated Sprint Ability (RAST) in Elite Soccer PlayersNutrients, Vol. 12, Pages 2961: The Effects of Long-Term Magnesium Creatine Chelate Supplementation on Repeated Sprint Ability (RAST) in Elite Soccer Players Nutrients doi: 10.3390/nu12102961 Authors: Adam Zajac Artur Golas Jakub Chycki Mateusz Halz Małgorzata Magdalena Michalczyk Aim: The aim of the study was to evaluate the effects...
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MoleculesMolecules, Vol. 25, Pages 4437: The Potential Role and Regulatory Mechanisms of MUC5AC in Chronic Obstructive Pulmonary DiseaseMolecules, Vol. 25, Pages 4437: The Potential Role and Regulatory Mechanisms of MUC5AC in Chronic Obstructive Pulmonary Disease Molecules doi: 10.3390/molecules25194437 Authors: Jingyuan Li Zuguang Ye Chronic obstructive pulmonary disease (COPD) is associated with high morbidity and mortality globally. Studies show that airway mucus hypersecretion strongly compromises...
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Journal of Clinical MedicineJCM, Vol. 9, Pages 3129: The Long-Term Outcomes of Intensive Combined Therapy of Adult Patients with Localised Synovial SarcomaJCM, Vol. 9, Pages 3129: The Long-Term Outcomes of Intensive Combined Therapy of Adult Patients with Localised Synovial Sarcoma Journal of Clinical Medicine doi: 10.3390/jcm9103129 Authors: Katarzyna Kozak Paweł Teterycz Tomasz Świtaj Hanna Koseła-Paterczyk Sławomir Falkowski Tadeusz Morysiński Ewa Bartnik Anna M. Czarnecka Michał Wągrodzki Iwona...
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International Journal of Environmental Research and Public HealthIJERPH, Vol. 17, Pages 7014: Is a View of Green Spaces from Home Associated with a Lower Risk of Anxiety and Depression?IJERPH, Vol. 17, Pages 7014: Is a View of Green Spaces from Home Associated with a Lower Risk of Anxiety and Depression? International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17197014 Authors: Olta Braçe Marco Garrido-Cumbrera Ronan Foley José Correa-Fernández Gina Suárez-Cáceres Raffaele...
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DiagnosticsDiagnostics, Vol. 10, Pages 751: Myocardial Function, Heart Failure and Arrhythmia in Marfan Syndrome: A Systematic Literature ReviewDiagnostics, Vol. 10, Pages 751: Myocardial Function, Heart Failure and Arrhythmia in Marfan Syndrome: A Systematic Literature Review Diagnostics doi: 10.3390/diagnostics10100751 Authors: Anthony Demolder Yskert von Kodolitsch Laura Muiño-Mosquera Julie De Backer Marfan syndrome (MFS) is a heritable systemic connective tissue disease with important cardiovascular...
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AntibioticsAntibiotics, Vol. 9, Pages 647: A Comparison of Colistin versus Colistin Plus Meropenem for the Treatment of Carbapenem-Resistant Acinetobacter baumannii in Critically Ill Patients: A Propensity Score-Matched AnalysisAntibiotics, Vol. 9, Pages 647: A Comparison of Colistin versus Colistin Plus Meropenem for the Treatment of Carbapenem-Resistant Acinetobacter baumannii in Critically Ill Patients: A Propensity Score-Matched Analysis Antibiotics doi: 10.3390/antibiotics9100647 Authors:...
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Brain SciencesBrain Sciences, Vol. 10, Pages 68...
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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
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