Publication date: February 2020Source: Oral and Maxillofacial Surgery Clinics of North America, Volume 32, Issue 1Author(s): Michael R. Markiewicz, Veerasathpurush Allareddy, Michael Miloro
Sun Nov 17, 2019 17:29
Publication date: Available online 16 November 2019Source: Sleep MedicineAuthor(s): Min Meng, Yanrui Jiang, Lixia Zhu, Guanghai Wang, Qingmin Lin, Wanqi Sun, Yuanjin Song, Shumei Dong, Yujiao Deng, Tingyu Rong, Qi Zhu, Hao Mei, Fan JiangAbstractObjectivesTo study the impact of maternal sleep in late pregnancy on birth weight (BW) and leptin and lipid levels in umbilical cord blood.Study DesignA total of 277 healthy and singleton pregnancy women were recruited for participation in the Shanghai Sleep...
Sun Nov 17, 2019 17:12
790 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2019/11/17PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sun Nov 17, 2019 17:03
Publication date: Available online 17 November 2019Source: Behavioural Brain ResearchAuthor(s): David C. Jewett, Anica Klockars, Travis R. Smith, Chloe Brunton, Mitchell A. Head, Rachel L. Tham, Andrew J. Kwilasz, Thomas W. Hahn, Jason M. Wiebelhaus, Eric E. Ewan, Regina M. Carroll, Martha K. Grace, Allen S. Levine, Pawel K. OlszewskiAbstractIt is well accepted that opioids promote feeding for reward. Some studies suggest a potential involvement in hunger-driven intake, but they suffer from the scarcity...
Sun Nov 17, 2019 16:55
Publication date: Available online 16 November 2019Source: Behavioural Brain ResearchAuthor(s): J.L. Peterman, J.D. White, A. Calcagno, C. Hagen, M. Quiring, K. Paulhus, T. Gurney, M.J. Eimerbrink, M. Curtis, G.W. Boehm, M.J. ChumleyAbstractResearch has demonstrated that stress can exacerbate AD pathology in transgenic mouse models of AD. The purpose of the present studies was to extend this work by determining whether a social stressor, isolation stress, would increase the number of Aβ plaques in...
Sun Nov 17, 2019 16:55
Publication date: Available online 16 November 2019Source: Behavioural Brain ResearchAuthor(s): Sayali GoreAbstractSynthetic cathinones share potent sympathomimetic properties with amphetamines due to their shared phenethylamine backbone. Despite recent work focused on understanding the behavioral effects of synthetic cathinones, a systematic comparison of neuropharmacology, behavior, and physiological effects with other stimulants, has remained elusive. In the present study, we explore the behavioral...
Sun Nov 17, 2019 16:55
Publication date: Available online 16 November 2019Source: Journal of Neuroscience MethodsAuthor(s): Christopher E. Larson, Ellis MengAbstractInformational density and relative accessibility of the peripheral nervous system make it an attractive site for therapeutic intervention. Electrode-based electrophysiological interfaces with peripheral nerves have been under development since the 1960s and, for several applications, have seen widespread clinical implementation. However, many applications require...
Sun Nov 17, 2019 16:52
Publication date: Available online 16 November 2019Source: Allergology InternationalAuthor(s): Maeve M. Kelleher, Lien Tran, Robert J. BoyleAbstractThe relationship between infant skin health and food allergy pathogenesis is the focus of intense research activity, on the basis that interventions to improve infant skin health may potentially lead to the prevention of food allergy. Current evidence does not provide conclusive findings on the mechanisms of food allergy development but does support the...
Sun Nov 17, 2019 16:13
Publication date: March 2020Source: Journal of Environmental Radioactivity, Volume 213Author(s): S. Akyil Erenturk, S. Haciyakupoglu, B.F. SenkalAbstractThis study deals with performance of removal of cesium (Cs+) and strontium (Sr2+) ions from synthetic aqueous solution using amino pyridine sulfone amid resin as a barrier material for nuclear waste storage areas to reduce environmental risk. The effects of adsorbate concentration, temperature and contact time on the efficiencies of the engineering...
Sun Nov 17, 2019 16:09
Publication date: February 2020Source: Cognitive Psychology, Volume 116Author(s): Agata Bochynska, Mila Vulchanova, Valentin Vulchanov, Barbara LandauAbstractPrevious studies have shown that the basic properties of the visual representation of space are reflected in spatial language. This close relationship between linguistic and non-linguistic spatial systems has been observed both in typical development and in some developmental disorders. Here we provide novel evidence for structural parallels...
Sun Nov 17, 2019 16:06
Publication date: Available online 16 November 2019Source: Journal of Acupuncture and Meridian StudiesAuthor(s): Chae Jeong Lim, Yeo Sung Yoon, Pan Dong RyuAbstractThe primo vascular system (PVS) is reported to have a periductium composed of cells with spherical or spindle-shaped nuclei and abundant cytoplasm. However, little is known about these periductium cells. In this study, we examined the morphological features of cells covering the PVS tissue isolated from the surface of abdominal organs...
Sun Nov 17, 2019 16:04
Publication date: Available online 16 November 2019Source: Journal of Acupuncture and Meridian StudiesAuthor(s): Ahmad Rastgarian, Hassanali Abedi, Hossein Kargar Jahromi, Safar Zarei, Arash Nematollahi, Esrafil Mansoori, Hadi SameniAbstractMelissa officinalis is one of the oldest herbal medicines commonly used in traditional medicine, which some studies have investigated its analgesic effect. This study is an attempt to investigate the effects of intrathecal administration of Melissa officinalis...
Sun Nov 17, 2019 16:04
Publication date: Available online 16 November 2019Source: Brain Research BulletinAuthor(s): Afzal Misrani, Sidra Tabassum, Meng Wang, Jian Chen, Li Yang, Cheng LongAbstractCurtailment of sleep in modern society leads to a spectrum of neuropsychiatric disorders. However, the molecular mechanisms underlying the effects of sleep deprivation (SD) remain elusive and currently there is no effective therapy to alleviate these effects. Here, we aimed to examine SD-induced cellular and molecular alterations...
Sun Nov 17, 2019 15:53
Publication date: Available online 16 November 2019Source: Additive ManufacturingAuthor(s): Lei Yan, Yitao Chen, Frank LiouAbstractFunctionally graded materials (FGMs) have attracted much research interest in the industry due to their graded material properties, which result from gradually distributed compositions or structures. In recent years, metallic FGMs have been widely studied, and additive manufacturing (AM) has become an important approach to build metallic FGMs. This paper aims to provide...
Sun Nov 17, 2019 15:51
Publication date: Available online 16 November 2019Source: Brazilian Journal of OtorhinolaryngologyAuthor(s): Thaís de Carvalho Pontes-Madruga, Francisco Bazilio Nogueira Neto, Fla'via Alencar de Barros Suzuki, Jose' Ricardo Gurgel Testa, Ektor Tsuneo OnishiAbstractIntroductionTympanoplasty is the surgical procedure aimed at the reconstruction of the tympanic membrane and restoration of the sound conducting mechanism. It can be performed with several types of access and grafts and is considered successful...
Sun Nov 17, 2019 15:48
38 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: ALCOHOL These pubmed results were generated on 2019/11/17PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sun Nov 17, 2019 15:41
Related ArticlesThe Relationship of Candida albicans with the Oral Bacterial Microbiome in Health and Disease. Adv Exp Med Biol. 2019;1197:69-78 Authors: Bertolini M, Dongari-Bagtzoglou A Abstract Candida albicans is an opportunistic pathogen colonizing the oropharyngeal, esophageal, and gastrointestinal mucosa in most healthy humans. In immunocompromised hosts, this fungal organism can cause mucosal candidiasis in these sites. C. albicans also causes...
Sun Nov 17, 2019 15:40
Related ArticlesInhibition of CD44 induces apoptosis, inflammation and matrix metalloproteinase expression in tendinopathy. J Biol Chem. 2019 Nov 15;: Authors: Wu PT, Su WR, Li CL, Hsieh JL, Ma CH, Wu CL, Kuo LC, Jou IM, Chen SY Abstract Apoptosis has emerged as a primary cause of tendinopathy. CD44 signaling pathways exert anti-apoptotic and -inflammatory effects on tumor cells, chondrocytes, and fibroblast-like synoviocytes. The aim of this study was...
Sun Nov 17, 2019 15:40
Related ArticlesMycoredoxins Are Required for Redox Homeostasis and Intracellular Survival in the Actinobacterial Pathogen Rhodococcus equi. Antioxidants (Basel). 2019 Nov 15;8(11): Authors: Mourenza Á, Bravo-Santano N, Pradal I, Gil JA, Mateos LM, Letek M Abstract Rhodococcus equi is a facultative intracellular pathogen that can survive within macrophages of a wide variety of hosts, including immunosuppressed humans. Current antibiotherapy is often...
Sun Nov 17, 2019 15:40
Cells, Vol. 8, Pages 1450: HIF1α-Dependent Metabolic Signals Control the Differentiation of Follicular Helper T Cells Cells doi: 10.3390/cells8111450 Authors: Dong He Zhou Cao Li Bi Liu Follicular helper T (TFH) cells are critical for germinal center (GC) formation and are responsible for effective B cell-mediated immunity; metabolic signaling is an important regulatory mechanism for the differentiation of TFH cells. However, the precise roles of hypoxia inducible...
Sun Nov 17, 2019 02:00
Cells, Vol. 8, Pages 1452: Let-7 miRNA’s Expression Profile and Its Potential Prognostic Role in Uterine Leiomyosarcoma Cells doi: 10.3390/cells8111452 Authors: de Almeida dos Anjos Uno Cunha Soares Baiocchi Baracat Carvalho The lethal-7 (let-7) family is an important microRNA (miRNA) group that usually exerts functions as a tumor suppressor. We aimed to evaluate the expression profile of let-7a, let-7b, let-7c, let-7d, let-7e, let-7f, let-7g, and let-7i...
Sun Nov 17, 2019 02:00
Cells, Vol. 8, Pages 1451: Functional Ultrastructure of the Excretory Gland Cell in Zoonotic Anisakids (Anisakidae, Nematoda) Cells doi: 10.3390/cells8111451 Authors: Mladineo Hrabar Smodlaka Palmer Sakamaki Keklikoglou Katharios Excretory and secretory products are crucial for parasite infectivity and host immunomodulation, but the functioning and ultrastructure of the excretory gland cell (EC) that produces these products are still scarcely understood and described....
Sun Nov 17, 2019 02:00
Cells, Vol. 8, Pages 1453: Targeting the Stress-Induced Protein NUPR1 to Treat Pancreatic Adenocarcinoma Cells doi: 10.3390/cells8111453 Authors: Santofimia-Castaño Xia Peng Velázquez-Campoy Abián Lan Lomberk Urrutia Rizzuti Soubeyran Neira Iovanna Cancer cells activate stress-response mechanisms to adapt themselves to a variety of stressful conditions. Among these protective mechanisms, those controlled by the stress-induced nuclear protein...
Sun Nov 17, 2019 02:00
Related ArticlesAndrogens and Androgen Receptor Actions on Bone Health and Disease: From Androgen Deficiency to Androgen Therapy. Cells. 2019 Oct 25;8(11): Authors: Chen JF, Lin PW, Tsai YR, Yang YC, Kang HY Abstract Androgens are not only essential for bone development but for the maintenance of bone mass. Therefore, conditions with androgen deficiency, such as male hypogonadism, androgen-insensitive syndromes, and prostate cancer with androgen deprivation...
Sun Nov 17, 2019 15:40
Related ArticlesDisease Associated Mutations in KIR Proteins Linked to Aberrant Inward Rectifier Channel Trafficking. Biomolecules. 2019 Oct 25;9(11): Authors: Zangerl-Plessl EM, Qile M, Bloothooft M, Stary-Weinzinger A, van der Heyden MAG Abstract The ubiquitously expressed family of inward rectifier potassium (KIR) channels, encoded by KCNJ genes, is primarily involved in cell excitability and potassium homeostasis. Channel mutations associate with...
Sun Nov 17, 2019 15:40
Publication date: April 2020Source: New Ideas in Psychology, Volume 57Author(s): Eleonora Florio, Letizia Caso, Ilaria CastelliAbstractThe term “adultcentrism” refers to a paradigm of thought that leads adults to provide inadequate or distorted responses to children’s needs (Furioso, 2000), despite the belief of acting in children’s best interest. Our understanding of adult-child relationship could be subjected to such adultcentric bias, thus preventing the acknowledgement of the deeply reciprocal...
Sun Nov 17, 2019 15:40
19 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human physiology These pubmed results were generated on 2019/11/17PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sun Nov 17, 2019 15:40
Publication date: Available online 17 November 2019Source: Artificial Intelligence in MedicineAuthor(s): Marta Fernandes, Susana M. Vieira, Francisca Leite, Carlos Palos, Stan Finkelstein, João M.C. SousaAbstractMotivationEmergency Departments’ (ED) modern triage systems implemented worldwide are solely based upon medical knowledge and experience. This is a limitation of these systems, since there might be hidden patterns that can be explored in big volumes of clinical historical data. Intelligent...
Sun Nov 17, 2019 15:29
Publication date: Available online 17 November 2019Source: Artificial Intelligence in MedicineAuthor(s): Gabriela Ochoa, Lee A. Christie, Alexander E. Brownlee, Andrew HoyleAbstractAntibiotic resistance is one of the major challenges we face in modern times. Antibiotic use, especially their overuse, is the single most important driver of antibiotic resistance. Efforts have been made to reduce unnecessary drug prescriptions, but limited work is devoted to optimising dosage regimes when they are prescribed....
Sun Nov 17, 2019 15:29
Publication date: Available online 17 November 2019Source: Artificial Intelligence in MedicineAuthor(s): Yu Lu, Xianghua Fu, Fangxiong Chen, Kelvin K.L. WongAbstractObstetric ultrasound examination of physiological parameters has been mainly used to estimate the fetal weight during pregnancy and baby weight before labour to monitor fetal growth and reduce prenatal morbidity and mortality. However, the problem is that ultrasound estimation of fetal weight is subject to populations’ difference, strict...
Sun Nov 17, 2019 15:29
Publication date: Available online 16 November 2019Source: Artificial Intelligence in MedicineAuthor(s): Yu Sun, Li Wang, Zhongliang Jiang, Bing Li, Ying Hu, Wei TianAbstractThe decompressive laminectomy is a common operation for treatment of lumbar spinal stenosis. The tools for grinding and drilling are used for fenestration and internal fixation, respectively. The state recognition is one of the main technologies in robot-assisted surgery, especially in tele-surgery, because surgeons have limited...
Sun Nov 17, 2019 15:29
Publication date: Available online 16 November 2019Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Shaghayegh Omidvar, Zahra Jeddi, Afsaneh Doosti, Seyed Basir HashemiAbstractObjectivesThe coincidence of attention-deficit/hyperactivity disorder (ADHD) and hearing loss in the children has adverse effects in speech, cognition, communication and motor development. This can influence cochlear implant (CI) outcomes negatively. The aim of this study was to compare auditory, language,...
Sun Nov 17, 2019 15:28
Publication date: Available online 17 November 2019Source: Journal of Clinical VirologyAuthor(s): Sacha Stelzer-Braid, Matthew Wynn, Richard Chatoor, Matthew Scotch, Vidiya Ramachandran, Hooi-Ling Teoh, Michelle A. Farrar, Hugo Sampaio, Peter Ian Andrews, Maria E. Craig, C. Raina MacIntyre, Hemalatha Varadhan, Alison Kesson, Philip N. Britton, James Newcombe, William D. RawlinsonAbstractBackgroundThe most recent documented Australian outbreak of enterovirus A71 (EV-A71) occurred in Sydney from 2012...
Sun Nov 17, 2019 15:28
Related ArticlesRole of Mechanistic Target of Rapamycin and Autophagy in Alcohol-Induced Adipose Atrophy and Liver Injury. Am J Pathol. 2019 Nov 13;: Authors: Li Y, Chao X, Wang S, Williams JA, Ni HM, Ding WX Abstract Chronic alcohol consumption induces adipose tissue atrophy. However, the mechanisms for how alcohol induces lipodystrophy and its impact on liver steatosis and injury are not fully elucidated. Autophagy is a highly conserved lysosomal degradation...
Sun Nov 17, 2019 15:26
Publication date: January 2020Source: Molecular Immunology, Volume 117Author(s): Tang Li, Ru-ru Chen, Hong-peng Gong, Bin-feng Wang, Xi-xi Wu, Yue-qiu Chen, Zhi-ming HuangAbstractInflammatory bowel disease (IBD) is an autoimmune disease characterized by an abnormal immune response. Fibrinogen-like protein 2 (FGL2) is known to have immunoregulatory and anti-inflammatory activity. The level of FGL2 is elevated in patients with IBD; however, its comprehensive function in IBD is almost unknown. In our...
Sun Nov 17, 2019 15:08
Publication date: December 2019Source: Data in Brief, Volume 27Author(s): Alex Asabre, Janine Pfetzing-Micklich, Oleg Stryzhyboroda, Aleksander Kostka, Ulrike Hecht, Guillaume LaplancheAbstractThis brief paper contains raw data of X-ray diffraction (XRD) measurements, microstructural characterization, chemical compositions, and mechanical properties describing the influence of Al, Ti, and C on as-cast Al0.6CoCrFeNi compositionally complex alloys (CCAs). The presented data are related to the research...
Sun Nov 17, 2019 15:07
Publication date: December 2019Source: Data in Brief, Volume 27Author(s): Andrea Paulillo, Alberto Striolo, Paola LettieriAbstractThis data article is related to the research article “The environmental impacts and the carbon intensity of geothermal energy: A case study on the Hellisheiði plant”. The article reports numerical values of the results of the Life Cycle Assessment (LCA) study, which are reported only graphically and in an aggregated form in the main article. Data include normalised impacts,...
Sun Nov 17, 2019 15:07
Publication date: December 2019Source: Data in Brief, Volume 27Author(s): Paola Pierleoni, Marco Mercuri, Alberto Belli, Massimo Pieri, Alessandro Marroni, Lorenzo PalmaAbstractThe article describes a dataset of doppler ultrasound audio tracks taken on a sample of 30 divers according to the acquisition protocol defined by the Divers Alert Network. The audio tracks are accompanied by a medical evaluation for the decompression sickness risk according to the Spencer's scale levels.During the acquisition...
Sun Nov 17, 2019 15:07
Publication date: Available online 16 November 2019Source: European Journal of Vascular and Endovascular SurgeryAuthor(s): Thea Kreutzburg, Frederik Peters, Henrik C. Rieß, Sandra Hischke, Ursula Marschall, Levente Kriston, Helmut L'Hoest, Art Sedrakyan, Eike S. Debus, Christian-Alexander BehrendtObjectivesPatients suffering from peripheral arterial occlusive disease (PAOD) are a central target population for multidisciplinary vascular medicine. This study aimed to highlight trends in treatment patterns...
Sun Nov 17, 2019 14:56
Publication date: Available online 16 November 2019Source: European Journal of Vascular and Endovascular SurgeryAuthor(s): Guang-Hui Shen, Ye Song, Ye Yao, Qing-Feng Sun, Bao Jing, Jia Wu, Shi-Yong Li, Si-Qi Liu, Hao-Cheng Li, Chao Yuan, Gao-Yan Liu, Jing-Bo Li, Xin-Yu Liu, Hai-Yang WangObjectiveThis study aimed to investigate the effect of long non-coding RNA (lncRNA) DLGAP1 antisense RNA 1 (DLGAP1-AS1) on vascular endothelial cell (VEC) injury via the phosphoinositide 3-kinase (PI3K)/Akt pathway...
Sun Nov 17, 2019 14:56
Abstract Diffuse optical tomography (DOT) is an emerging imaging technique which uses light for diagnostic purposes in non‐invasive and non‐ionizing way. In this paper, we focus on DOT application to female breast screening, where the surface of the breast is illuminated by light sources and the outgoing light is collected on the surface. The comparison of measured light data with the equivalent field obtained from a relevant mathematical model yields the DOT inverse problem whose solution provides...
Sat Nov 16, 2019 12:18
Dentistry Journal, Vol. 7, Pages 107: Biological Effects of Anodic Oxidation on Titanium Miniscrews: An In Vitro Study on Human Cells Dentistry Journal doi: 10.3390/dj7040107 Authors: Iodice Perinetti Ludwig Polishchuk Polishchuk This controlled in vitro study compared the effects of varying the thickness of a TiO2 layer on cellular activity using commercially available miniscrew samples with identical surface features to derive information with direct clinical impact....
Sun Nov 17, 2019 02:00
Publication date: Available online 17 November 2019Source: Actas Dermo-SifiliográficasAuthor(s): J. Magdaleno-Tapial, P. Hernández-Bel, C. Valenzuela-Oñate, J.M. Ortiz-Salvador, M. García-Legaz-Martínez, Á. Martínez-Domenech, G. Pérez-Pastor, A. Esteve-Martínez, V. Zaragoza-Ninet, J.L. Sánchez-Carazo, V. Alegre-de Miquel, A. Pérez-FerriolsResumenIntroducción y objetivoSe ha constatado un cambio en la epidemiología del herpes genital en los últimos años con un aumento de la incidencia del virus herpes...
Sun Nov 17, 2019 14:05
JCM, Vol. 8, Pages 2009: Geographic Differences in Phenotype and Treatment of Children with Sickle Cell Anemia from the Multinational DOVE Study Journal of Clinical Medicine doi: 10.3390/jcm8112009 Authors: Inusa Colombatti Rees Heeney Hoppe Ogutu Hassab Zhou Yao Brown Heath Jakubowski Abboud Background: DOVE (Determining Effects of Platelet Inhibition on Vaso-Occlusive Events) was a Phase 3, randomized, double-blind, placebo-controlled...
Sun Nov 17, 2019 02:00
JCM, Vol. 8, Pages 2007: Advanced MRI Assessment during Dendritic Cell Immunotherapy Added to Standard Treatment Against Glioblastoma Journal of Clinical Medicine doi: 10.3390/jcm8112007 Authors: Cuccarini Aquino Gioppo Anghileri Pellegatta Schettino Mazzi Finocchiaro Bruzzone Eoli Evaluating changes induced by immunotherapies (IT) on conventional magnetic resonance imaging (MRI) is difficult because those treatments may produce inflammatory responses....
Sun Nov 17, 2019 02:00
JCM, Vol. 8, Pages 2008: Pulsed Electromagnetic Field Therapy Improves Osseous Consolidation after High Tibial Osteotomy in Elderly Patients—A Randomized, Placebo-Controlled, Double-Blind Trial Journal of Clinical Medicine doi: 10.3390/jcm8112008 Authors: Patrick Ziegler Andreas K. Nussler Benjamin Wilbrand Karsten Falldorf Fabian Springer Anne-Kristin Fentz Georg Eschenburg Andreas Ziegler Ulrich Stöckle Elke Maurer Atesch Ateschrang Steffen Schröter Sabrina...
Sun Nov 17, 2019 02:00
Abstract Clemens Peter Freiherr (= Baron) von Pirquet (Figure 1) was born in Hirschstetten near Vienna on 12 May 1847 into a patrician family originally from Liège. His father Peter Zeno was a member of parliament. His mother Flora Freiin (= Baroness) von Pereira‐Arnstein came from an assimilated Jewish banking family but had been brought up Catholic.
Sat Nov 16, 2019 17:24
Abstract Food allergies have become a significant heath burden as prevalence continues to rise, affecting 6‐13% of the global population. In the absence of drugs approved by regulatory agencies, the current standard of care remains avoidance of allergenic foods and management of acute allergic reactions with antihistamines and epinephrine auto‐injectors. Allergen immunotherapy has been shown to increase the threshold of reactivity in the majority of food‐allergic individuals. However, challenges...
Sat Nov 16, 2019 17:09
Pathogens, Vol. 8, Pages 241: LmxM.22.0250-Encoded Dual Specificity Protein/Lipid Phosphatase Impairs Leishmania mexicana Virulence In Vitro Pathogens doi: 10.3390/pathogens8040241 Authors: Natalya Kraeva Tereza Leštinová Aygul Ishemgulova Karolina Majerová Anzhelika Butenko Slavica Vaselek Julia Bespyatykh Arzuv Charyyeva Tatiana Spitzová Alexei Yu. Kostygov Julius Lukeš Petr Volf Jan Votýpka Vyacheslav Yurchenko Protein phosphorylation/dephosphorylation...
Sun Nov 17, 2019 02:00
Brain Sciences, Vol. 9, Pages 328: Antinociceptive and Abuse Potential Effects of Cannabinoid/Opioid Combinations in a Chronic Pain Model in Rats Brain Sciences doi: 10.3390/brainsci9110328 Authors: Alsalem Altarifi Haddad Aldossary Kalbouneh Aldaoud Saleh El-Salem Chronic pain is a persistent and debilitating health problem. Although the use of analgesics such as opioids is useful in mitigating pain, their prolonged use is associated with unwanted effects...
Sun Nov 17, 2019 02:00
Abstract CCR9+ T helper (Th) cells can induce Sjögren‐like symptoms in mice and both CCR9+ Th‐cells and their ligand CCL25 are increased in the salivary glands of primary Sjögren's syndrome (pSS) patients. Increased circulating CCR9+ Th cells are present in pSS patients. CCR9+ Th cells are hyperresponsive to IL‐7, secrete high levels of IFN‐γ, IL‐21, IL‐17 and IL‐4 and potently stimulate B cells in both patients and healthy individuals. Our aim was to study co‐expression of chemokine receptors on...
Sat Nov 16, 2019 16:45
Abstract Acute liver injury is a common pathological basis for a variety of acute liver diseases in the clinic, which can eventually lead to liver fibrosis and even liver failure. In this study, we found that T cell Ig and mucin domain protein 3 (Tim‐3) and TLR4 receptors play important roles in CCl4‐induced acute liver injury. Tim‐3 is a negative regulator that is expressed by T cells and macrophages. Using antibodies against Tim‐3 (anti‐Tim‐3 Ab), we studied the Tim‐3 signal in an animal model...
Sat Nov 16, 2019 16:14
Abstract Cervical Cancer incidence worldwide exceeds half a million new cases per year. The papilloma virus (HPV) being the major causative agent of CC uses a variety of strategies to evade immune surveillance, where the immune status varies amongst individuals. This immune evasion altered by HPV is reflected in persistent infections, causing the evolution of cervical neoplasia. The role of the immune system in viral recognition and elimination is of extreme relevance in the development of CC. The...
Sat Nov 16, 2019 16:03
Cancer is an important cause of morbidity and mortality worldwide. In Africa, studies focusing on childhood cancer showed a constant increase in the annual number of new cases and a very low overall survival rate.1 Cancer treatment is often associated with pain management. The World Health Organization's guidelines recommend oral morphine (hydrochloride or sulfate) for severe chronic pain treatment in children. A previous work evidenced the good feasibility of oral morphine solution in Uganda.2 However,...
Thu Oct 24, 2019 00:00
Patients with decompensated cirrhosis have high rates of health care utilization at end of life (EOL). However, the impact of transplant candidacy on intensity of EOL care is currently unknown. (Source: Journal of Pain and Symptom Management)
Wed Oct 23, 2019 00:00
Video games like The Outer Worlds are beginning to match the imagination and flexibility of tabletop RPGs. Just add bigger data sets and computing power, says Jacob Aron in his latest column
Wed Nov 13, 2019 20:00
Publication date: Available online 16 November 2019Source: Revue de MicropaléontologieAuthor(s): Abdel-Mohsen M. Morsi, Abdel-Galil A. Hewaidy, Ahmed SamirAbstractEighteen new ostracod species are recorded from the Maastrichtian-lower Eocene stratigraphic succession exposed at the Kharga Oasis in the Western Desert of Egypt. The new findings include eleven newly erected species, besides seven species recorded for the first time but left in open nomenclature. They have been taxonomically described...
Sun Nov 17, 2019 13:12
Abstract Arsenic (As) accumulation in rice is a principal route of As exposure for rice based population. We have tested physiochemical and molecular parameters together to identify low As accumulating rice cultivars with normal growth and vigor. The present study examined potential toxicity caused by arsenate (AsV) among four rice cultivars tested that varied with respect to accumulation of total arsenic, arsenite (AsIII) and their differential translocation rate which had deleterious...
Sun Nov 17, 2019 02:00
Pharmaceuticals, Vol. 12, Pages 169: Biological Evaluation of Arylsemicarbazone Derivatives as Potential Anticancer Agents Pharmaceuticals doi: 10.3390/ph12040169 Authors: Nascimento da Cruz Brondani I´talo de Santana Oliveira da Silva da Oliveira Borba de Faria Ferreira Cavalcanti de Albuquerque Piessard Matos Ximenes Baratte Bach Ruchaud Bezerra Mendonça Junior Bazin Montenegro Rabello Hernandes Marchand Gonçalves da...
Sun Nov 17, 2019 02:00
Abstract The relationship of evolution with diet and environment can provide insights into modern disease. Fossil evidence shows apes and early human ancestors were fruit‐eaters living in environments with strongly seasonal climates. Rapid cooling at the end of the middle Miocene (15‐12Ma: millions of years ago) increased seasonality in Africa and Europe, and ape survival may be linked with a mutation in uric acid metabolism. Climate stabilized in the later Miocene and Pliocene (12‐5Ma),...
Sat Nov 16, 2019 18:38
Abstract In 2007, human papillomavirus (HPV) type 16 was finally recognized as a risk factor, besides smoking and alcohol, for oropharyngeal squamous cell carcinoma (OPSCC), including tonsillar squamous cell carcinoma (TSCC), by the International Agency for Research against Cancer. Just before, in 2006, the Food and Drug Administration had approved Gardasil, the first vaccine against HPV16, 18, 6 and 11, for preventive vaccination women against cervical cancer. Concurrently, some Western...
Sat Nov 16, 2019 16:00
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