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Τετάρτη 13 Νοεμβρίου 2019


IJMS, Vol. 20, Pages 5695: Extracellular Vesicles—Connecting Kingdoms
IJMS, Vol. 20, Pages 5695: Extracellular Vesicles—Connecting Kingdoms International Journal of Molecular Sciences doi: 10.3390/ijms20225695 Authors: Eric Woith Gregor Fuhrmann Matthias F. Melzig It is known that extracellular vesicles (EVs) are shed from cells of almost every type of cell or organism, showing their ubiquity in all empires of life. EVs are defined as naturally released particles from cells, delimited by a lipid bilayer, and cannot replicate. These nano- to micrometer...
International Journal of Molecular Sciences
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IJMS, Vol. 20, Pages 5698: Inhibition of the Adenosinergic Pathway in Cancer Rejuvenates Innate and Adaptive Immunity
IJMS, Vol. 20, Pages 5698: Inhibition of the Adenosinergic Pathway in Cancer Rejuvenates Innate and Adaptive Immunity International Journal of Molecular Sciences doi: 10.3390/ijms20225698 Authors: Juliana Hofstätter Azambuja Nils Ludwig Elizandra Braganhol Theresa L. Whiteside The adenosine pathway plays a key role in modulating immune responses in physiological and pathological conditions. Physiologically, anti-inflammatory effects of adenosine balance pro-inflammatory adenosine...
International Journal of Molecular Sciences
02:00
IJMS, Vol. 20, Pages 5696: Antibacterial Activity and Anti-Quorum Sensing Mediated Phenotype in Response to Essential Oil from Melaleuca bracteata Leaves
IJMS, Vol. 20, Pages 5696: Antibacterial Activity and Anti-Quorum Sensing Mediated Phenotype in Response to Essential Oil from Melaleuca bracteata Leaves International Journal of Molecular Sciences doi: 10.3390/ijms20225696 Authors: Wenting Wang Xiaoqin Huang Huixiang Yang Xianqian Niu Dongxiang Li Chao Yang Liang Li Liting Zou Ziwen Qiu Shaohua Wu Yongyu Li The prominent antibacterial and quorum sensing (QS) inhibition activity of aromatic plants can be...
International Journal of Molecular Sciences
02:00
IJMS, Vol. 20, Pages 5693: Strategies to Obtain Designer Polymers Based on Cyanobacterial Extracellular Polymeric Substances (EPS)
IJMS, Vol. 20, Pages 5693: Strategies to Obtain Designer Polymers Based on Cyanobacterial Extracellular Polymeric Substances (EPS) International Journal of Molecular Sciences doi: 10.3390/ijms20225693 Authors: Sara B. Pereira Aureliana Sousa Marina Santos Marco Araújo Filipa Serôdio Pedro Granja Paula Tamagnini Biopolymers derived from polysaccharides are a sustainable and environmentally friendly alternative to the synthetic counterparts available in the market. Due...
International Journal of Molecular Sciences
02:00
IJMS, Vol. 20, Pages 5694: The Role of Vascular Smooth Muscle Cells in Arterial Remodeling: Focus on Calcification-Related Processes
IJMS, Vol. 20, Pages 5694: The Role of Vascular Smooth Muscle Cells in Arterial Remodeling: Focus on Calcification-Related Processes International Journal of Molecular Sciences doi: 10.3390/ijms20225694 Authors: Armand Jaminon Koen Reesink Abraham Kroon Leon Schurgers Arterial remodeling refers to the structural and functional changes of the vessel wall that occur in response to disease, injury, or aging. Vascular smooth muscle cells (VSMC) play a pivotal role in regulating...
International Journal of Molecular Sciences
02:00
IJMS, Vol. 20, Pages 5692: Brain Susceptibility to Methyl Donor Deficiency: from Fetal Programming to Aging Outcome in Rats
IJMS, Vol. 20, Pages 5692: Brain Susceptibility to Methyl Donor Deficiency: from Fetal Programming to Aging Outcome in Rats International Journal of Molecular Sciences doi: 10.3390/ijms20225692 Authors: Ziad Hassan David Coelho Tunay Kokten Jean-Marc Alberto Rémy Umoret Jean-Luc Daval Jean-Louis Guéant Carine Bossenmeyer-Pourié Grégory Pourié Deficiencies in methyl donors, folate, and vitamin B12 are known to lead to brain function defects. Fetal development is...
International Journal of Molecular Sciences
02:00
IJMS, Vol. 20, Pages 5690: Role of the Balance of Akt and MAPK Pathways in the Exercise-Regulated Phenotype Switching in Spontaneously Hypertensive Rats
IJMS, Vol. 20, Pages 5690: Role of the Balance of Akt and MAPK Pathways in the Exercise-Regulated Phenotype Switching in Spontaneously Hypertensive Rats International Journal of Molecular Sciences doi: 10.3390/ijms20225690 Authors: Lin Zhang Yanyan Zhang Ying Wu Jingjing Yu Yimin Zhang Fanxing Zeng Lijun Shi The mechanisms regulating vascular smooth muscle cell (VSMC) phenotype switching and the critical signal modulation affecting the VSMCs remain controversial. Physical...
International Journal of Molecular Sciences
Wed Nov 13, 2019 02:00
IJMS, Vol. 20, Pages 5691: Alpha-Lipoic Acid Ameliorates Radiation-Induced Lacrimal Gland Injury through NFAT5-Dependent Signaling
IJMS, Vol. 20, Pages 5691: Alpha-Lipoic Acid Ameliorates Radiation-Induced Lacrimal Gland Injury through NFAT5-Dependent Signaling International Journal of Molecular Sciences doi: 10.3390/ijms20225691 Authors: Hyuna Kim Woong-Sun Yoo Jung Hwa Jung Bae Kwon Jeong Seung Hoon Woo Jin Hyun Kim Seong Jae Kim Dry eye syndrome related to radiation therapy is relatively common and can severely impair a patient’s daily life. The nuclear factor of activated T cells...
International Journal of Molecular Sciences
Wed Nov 13, 2019 02:00
IJMS, Vol. 20, Pages 5689: DEK Is a Potential Biomarker Associated with Malignant Phenotype in Gastric Cancer Tissues and Plasma
IJMS, Vol. 20, Pages 5689: DEK Is a Potential Biomarker Associated with Malignant Phenotype in Gastric Cancer Tissues and Plasma International Journal of Molecular Sciences doi: 10.3390/ijms20225689 Authors: Kam-Fai Lee Ming-Ming Tsai Chung-Ying Tsai Chung-Guei Huang Yu-Hsiang Ou Ching-Chuan Hsieh Hsi-Lung Hsieh Chia-Siu Wang Kwang-Huei Lin Gastric cancer (GC) is the second most widespread cause of cancer-related mortality worldwide. The discovery of novel biomarkers...
International Journal of Molecular Sciences
Wed Nov 13, 2019 02:00
IJMS, Vol. 20, Pages 5686: Conditional Deletion of Dicer in Adult Mice Impairs Skeletal Muscle Regeneration
IJMS, Vol. 20, Pages 5686: Conditional Deletion of Dicer in Adult Mice Impairs Skeletal Muscle Regeneration International Journal of Molecular Sciences doi: 10.3390/ijms20225686 Authors: Satoshi Oikawa Minjung Lee Takayuki Akimoto Skeletal muscle has a remarkable regenerative capacity, which is orchestrated by multiple processes, including the proliferation, fusion, and differentiation of the resident stem cells in muscle. MicroRNAs (miRNAs) are small noncoding RNAs that mediate...
International Journal of Molecular Sciences
Wed Nov 13, 2019 02:00
IJMS, Vol. 20, Pages 5687: Examination of the Changes in Calcium Homeostasis in the Delayed Antiarrhythmic Effect of Sodium Nitrite
IJMS, Vol. 20, Pages 5687: Examination of the Changes in Calcium Homeostasis in the Delayed Antiarrhythmic Effect of Sodium Nitrite International Journal of Molecular Sciences doi: 10.3390/ijms20225687 Authors: Vivien Demeter-Haludka Mária Kovács János Prorok Norbert Nagy András Varró Ágnes Végh We have evidence that the intravenous infusion of sodium nitrite (NaNO2) results in an antiarrhythmic effect when given 24 h prior to an ischemia and reperfusion (I/R) insult in...
International Journal of Molecular Sciences
Wed Nov 13, 2019 02:00
IJMS, Vol. 20, Pages 5688: Neuroplasticity in Cholinergic Projections from the Basal Forebrain to the Basolateral Nucleus of the Amygdala in the Kainic Acid Model of Temporal Lobe Epilepsy
IJMS, Vol. 20, Pages 5688: Neuroplasticity in Cholinergic Projections from the Basal Forebrain to the Basolateral Nucleus of the Amygdala in the Kainic Acid Model of Temporal Lobe Epilepsy International Journal of Molecular Sciences doi: 10.3390/ijms20225688 Authors: Ítalo Rosal Lustosa Joana I. Soares Giuseppe Biagini Nikolai V. Lukoyanov The amygdala is a cerebral region whose function is compromised in temporal lobe epilepsy (TLE). Patients with TLE present cognitive and...
International Journal of Molecular Sciences
Wed Nov 13, 2019 02:00
IJMS, Vol. 20, Pages 5684: The Alteration of CTNNBIP1 in Lung Cancer
IJMS, Vol. 20, Pages 5684: The Alteration of CTNNBIP1 in Lung Cancer International Journal of Molecular Sciences doi: 10.3390/ijms20225684 Authors: Jia-Ming Chang Alexander Charng-Dar Tsai Way-Ren Huang Ruo-Chia Tseng β-catenin is a major component of the Wnt/β-catenin signaling pathway, and is known to play a role in lung tumorigenesis. β-catenin-interacting protein 1 (CTNNBIP1) is a known repressor of β-catenin transactivation. However,...
International Journal of Molecular Sciences
Wed Nov 13, 2019 02:00
IJMS, Vol. 20, Pages 5685: Recovery in the Myogenic Program of Congenital Myotonic Dystrophy Myoblasts after Excision of the Expanded (CTG)n Repeat
IJMS, Vol. 20, Pages 5685: Recovery in the Myogenic Program of Congenital Myotonic Dystrophy Myoblasts after Excision of the Expanded (CTG)n Repeat International Journal of Molecular Sciences doi: 10.3390/ijms20225685 Authors: Laurène M. André Remco T.P. van Cruchten Marieke Willemse Karel Bezstarosti Jeroen A.A. Demmers Ellen L. van Agtmaal Derick G. Wansink Bé Wieringa The congenital form of myotonic dystrophy type 1 (cDM) is caused by the large-scale expansion...
International Journal of Molecular Sciences
Wed Nov 13, 2019 02:00
IJMS, Vol. 20, Pages 5683: The Role of Obesity in Renal Cell Carcinoma Patients: Clinical-Pathological Implications
IJMS, Vol. 20, Pages 5683: The Role of Obesity in Renal Cell Carcinoma Patients: Clinical-Pathological Implications International Journal of Molecular Sciences doi: 10.3390/ijms20225683 Authors: Gaetano Aurilio Francesco Piva Matteo Santoni Alessia Cimadamore Giulia Sorgentoni Antonio Lopez-Beltran Liang Cheng Nicola Battelli Franco Nolè Rodolfo Montironi Obesity is a well-known risk factor for renal cell carcinoma (RCC) development. However, the RCC–obesity...
International Journal of Molecular Sciences
Wed Nov 13, 2019 02:00
IJMS, Vol. 20, Pages 5682: Gene Expression Profiles Induced by a Novel Selective Peroxisome Proliferator-Activated Receptor α Modulator (SPPARMα) Pemafibrate
IJMS, Vol. 20, Pages 5682: Gene Expression Profiles Induced by a Novel Selective Peroxisome Proliferator-Activated Receptor α Modulator (SPPARMα) Pemafibrate International Journal of Molecular Sciences doi: 10.3390/ijms20225682 Authors: Yusuke Sasaki Sana Raza-Iqbal Toshiya Tanaka Kentaro Murakami Motonobu Anai Tsuyoshi Osawa Yoshihiro Matsumura Juro Sakai Tatsuhiko Kodama Pemafibrate is the first clinically-available selective peroxisome proliferator-activated...
International Journal of Molecular Sciences
Wed Nov 13, 2019 02:00
IJMS, Vol. 20, Pages 5680: The Importance of HLA Assessment in “Off-the-Shelf” Allogeneic Mesenchymal Stem Cells Based-Therapies
IJMS, Vol. 20, Pages 5680: The Importance of HLA Assessment in “Off-the-Shelf” Allogeneic Mesenchymal Stem Cells Based-Therapies International Journal of Molecular Sciences doi: 10.3390/ijms20225680 Authors: Marta Kot Monika Baj-Krzyworzeka Rafał Szatanek Aleksandra Musiał-Wysocka Magdalena Suda-Szczurek Marcin Majka The need for more effective therapies of chronic and acute diseases has led to the attempts of developing more adequate and less invasive treatment methods....
International Journal of Molecular Sciences
Wed Nov 13, 2019 02:00
IJMS, Vol. 20, Pages 5679: Epigenetic Mechanisms and Posttranslational Modifications in Systemic Lupus Erythematosus
IJMS, Vol. 20, Pages 5679: Epigenetic Mechanisms and Posttranslational Modifications in Systemic Lupus Erythematosus International Journal of Molecular Sciences doi: 10.3390/ijms20225679 Authors: Elkin Navarro Quiroz Valeria Chavez-Estrada Karime Macias-Ochoa María Fernanda Ayala-Navarro Aniyensy Sarai Flores-Aguilar Francisco Morales-Navarrete Fernando de la Cruz Lopez Lorena Gomez Escorcia Carlos G. Musso Gustavo Aroca Martinez Henry Gonzales Torres Anderson...
International Journal of Molecular Sciences
Wed Nov 13, 2019 02:00
IJMS, Vol. 20, Pages 5678: Goals and Challenges in Bacterial Phosphoproteomics
IJMS, Vol. 20, Pages 5678: Goals and Challenges in Bacterial Phosphoproteomics International Journal of Molecular Sciences doi: 10.3390/ijms20225678 Authors: Paula Yagüe Nathaly Gonzalez-Quiñonez Gemma Fernánez-García Sergio Alonso-Fernández Angel Manteca Reversible protein phosphorylation at serine, threonine and tyrosine is a well-known dynamic post-translational modification with stunning regulatory and signalling functions in eukaryotes. Shotgun phosphoproteomic analyses...
International Journal of Molecular Sciences
Wed Nov 13, 2019 02:00
IJMS, Vol. 20, Pages 5681: Perinatal Use of Melatonin for Offspring Health: Focus on Cardiovascular and Neurological Diseases
IJMS, Vol. 20, Pages 5681: Perinatal Use of Melatonin for Offspring Health: Focus on Cardiovascular and Neurological Diseases International Journal of Molecular Sciences doi: 10.3390/ijms20225681 Authors: Chien-Ning Hsu Li-Tung Huang You-Lin Tain Cardiovascular and neurological diseases can originate in early life. Melatonin, a biologically active substance, acts as a pleiotropic hormone essential for pregnancy and fetal development. Maternal melatonin can easily pass the placenta...
International Journal of Molecular Sciences
Wed Nov 13, 2019 02:00
IJMS, Vol. 20, Pages 5677: Development and Characterization of a Genetic Mouse Model of KRAS Mutated Colorectal Cancer
IJMS, Vol. 20, Pages 5677: Development and Characterization of a Genetic Mouse Model of KRAS Mutated Colorectal Cancer International Journal of Molecular Sciences doi: 10.3390/ijms20225677 Authors: Radhashree Maitra Thongthai Thavornwatanayong Madhu Kumar Venkatesh Carol Chandy Dov Vachss Titto Augustine Hillary Guzik Wade Koba Qiang Liu Sanjay Goel Patients with KRAS mutated colorectal cancer (CRC) represent a cohort with unmet medical needs, with limited...
International Journal of Molecular Sciences
Wed Nov 13, 2019 02:00
IJNS, Vol. 5, Pages 42: Family Perspectives on Newborn Screening for X-Linked Adrenoleukodystrophy in California
IJNS, Vol. 5, Pages 42: Family Perspectives on Newborn Screening for X-Linked Adrenoleukodystrophy in California International Journal of Neonatal Screening doi: 10.3390/ijns5040042 Authors: Katharina Schwan Janey Youngblom Kara Weisiger Jessica Kianmahd Rebecca Waggoner Joanna Fanos X-linked adrenoleukodystrophy (ALD) is caused by gene variants in the ABCD1 gene, resulting in a varied clinical spectrum. Males with ALD present with symptoms ranging from isolated adrenal...
International Journal of Neonatal Screening
Wed Nov 13, 2019 02:00
JCM, Vol. 8, Pages 1962: The Clinicopathological Spectrum of Acromegaly
JCM, Vol. 8, Pages 1962: The Clinicopathological Spectrum of Acromegaly Journal of Clinical Medicine doi: 10.3390/jcm8111962 Authors: Amit Akirov Sylvia L. Asa Lama Amer Ilan Shimon Shereen Ezzat Background: Acromegaly results from a persistent excess in growth hormone with clinical features that may be subtle or severe. The most common cause of acromegaly is a pituitary tumor that causes excessive production of growth hormone (GH), and rare cases are due to an excess of...
Journal of Clinical Medicine
Wed Nov 13, 2019 02:00
JCM, Vol. 8, Pages 1960: Incidence and Risk Factors for Tractional Macular Detachment after Anti-Vascular Endothelial Growth Factor Agent Pretreatment before Vitrectomy for Complicated Proliferative Diabetic Retinopathy
JCM, Vol. 8, Pages 1960: Incidence and Risk Factors for Tractional Macular Detachment after Anti-Vascular Endothelial Growth Factor Agent Pretreatment before Vitrectomy for Complicated Proliferative Diabetic Retinopathy Journal of Clinical Medicine doi: 10.3390/jcm8111960 Authors: Andrea Russo Antonio Longo Teresio Avitabile Vincenza Bonfiglio Matteo Fallico Francesco Boscia Claudio Furino Salvatore Cillino Mario Toro Robert Rejdak Katarzyna Nowomiejska Michele...
Journal of Clinical Medicine
Wed Nov 13, 2019 02:00
JCM, Vol. 8, Pages 1959: The Scope for Thalassemia Gene Therapy by Disruption of Aberrant Regulatory Elements
JCM, Vol. 8, Pages 1959: The Scope for Thalassemia Gene Therapy by Disruption of Aberrant Regulatory Elements Journal of Clinical Medicine doi: 10.3390/jcm8111959 Authors: Petros Patsali Claudio Mussolino Petros Ladas Argyro Floga Annita Kolnagou Soteroula Christou Maria Sitarou Michael N. Antoniou Toni Cathomen Carsten Werner Lederer Marina Kleanthous The common IVSI-110 (G>A) β-thalassemia mutation is a paradigm for intronic disease-causing...
Journal of Clinical Medicine
Wed Nov 13, 2019 02:00
JCM, Vol. 8, Pages 1961: Association of CTLA4 Gene Polymorphism with Transfusion Reaction after Infusion of Leukoreduced Blood Component
JCM, Vol. 8, Pages 1961: Association of CTLA4 Gene Polymorphism with Transfusion Reaction after Infusion of Leukoreduced Blood Component Journal of Clinical Medicine doi: 10.3390/jcm8111961 Authors: Ying-Hao Wen Wei-Tzu Lin Wei-Ting Wang Tzong-Shi Chiueh Ding-Ping Chen Leukocytes and cytokines in blood units have been known to be involved in febrile non-hemolytic transfusion reaction (FNHTR), and these adverse reactions still occur while using pre-storage leukoreduced blood...
Journal of Clinical Medicine
Wed Nov 13, 2019 02:00
JCM, Vol. 8, Pages 1957: Recent Advances in Liquid Biopsy Based on Circulating Tumor DNA
JCM, Vol. 8, Pages 1957: Recent Advances in Liquid Biopsy Based on Circulating Tumor DNA Journal of Clinical Medicine doi: 10.3390/jcm8111957 Authors: Yu Sakuma Keita Fujii Jiayan Han Ryou-u Takahashi Many types of cells secrete DNA, RNA, and proteins through microvesicles, such as exosomes and apoptotic bodies, for the purpose of extracellular communication [...]
Journal of Clinical Medicine
Wed Nov 13, 2019 02:00
JCM, Vol. 8, Pages 1958: Salivary IL-6 mRNA is a Robust Biomarker in Oral Squamous Cell Carcinoma
JCM, Vol. 8, Pages 1958: Salivary IL-6 mRNA is a Robust Biomarker in Oral Squamous Cell Carcinoma Journal of Clinical Medicine doi: 10.3390/jcm8111958 Authors: Ildikó Judit Márton József Horváth Péter Lábiscsák Bernadett Márkus Balázs Dezső Adrienn Szabó Ildikó Tar József Piffkó Petra Jakus József Barabás Péter Barabás Lajos Olasz Zsanett Kövér József Tőzsér János Sándor Éva Csősz Beáta Scholtz Csongor Kiss Salivary IL-6 mRNA was previously...
Journal of Clinical Medicine
Wed Nov 13, 2019 02:00
JCM, Vol. 8, Pages 1954: Nuclear Factor-κB Overexpression is Correlated with Poor Outcomes after Multimodality Bladder-Preserving Therapy in Patients with Muscle-Invasive Bladder Cancer
JCM, Vol. 8, Pages 1954: Nuclear Factor-κB Overexpression is Correlated with Poor Outcomes after Multimodality Bladder-Preserving Therapy in Patients with Muscle-Invasive Bladder Cancer Journal of Clinical Medicine doi: 10.3390/jcm8111954 Authors: Yun Chiang Chung-Chieh Wang Yu-Chieh Tsai Chao-Yuan Huang Yeong-Shiau Pu Chia-Chi Lin Jason Chia-Hsien Cheng The aim of this study was to investigate prognostic molecular targets for selecting patients with muscle-invasive...
Journal of Clinical Medicine
Wed Nov 13, 2019 02:00
JCM, Vol. 8, Pages 1955: Mucins and Asthma: Are We Headed to the Revolutionary Road?
JCM, Vol. 8, Pages 1955: Mucins and Asthma: Are We Headed to the Revolutionary Road? Journal of Clinical Medicine doi: 10.3390/jcm8111955 Authors: Pierachille Santus Dejan Radovanovic Davide Alberto Chiumello Mucus represents the first line of defense of our respiratory tract and mucociliary clearance is essential for maintaining the homeostasis of airway epithelium. The latter mechanisms are altered in asthma and mucus plugging of proximal and distal airways is the main cause...
Journal of Clinical Medicine
Wed Nov 13, 2019 02:00
JCM, Vol. 8, Pages 1956: Vulnerability to Psychosis, Ideas of Reference and Evaluation with an Implicit Test
JCM, Vol. 8, Pages 1956: Vulnerability to Psychosis, Ideas of Reference and Evaluation with an Implicit Test Journal of Clinical Medicine doi: 10.3390/jcm8111956 Authors: Pedro Bendala-Rodríguez Cristina Senín-Calderón Leonardo Peluso-Crespi Juan F. Rodríguez-Testal Background: Ideas of reference (IRs) are observed in the general population on the continuum of the psychotic phenotype (as a type of psychotic-like experiences, PLE). The instruments usually used to evaluate IRs...
Journal of Clinical Medicine
Wed Nov 13, 2019 02:00
JCM, Vol. 8, Pages 1953: Oxidative Stress in COPD
JCM, Vol. 8, Pages 1953: Oxidative Stress in COPD Journal of Clinical Medicine doi: 10.3390/jcm8111953 Authors: María Magallón María Mercedes Navarro-García Francisco Dasí Numerous studies over the years have shown that oxidative stress plays a major role in the development of the disease. Oxidative stress involvement in COPD opens up the possibility of using antioxidant therapies in the treatment of the disease. However, so far, these therapies have shown no clinical benefit indicating...
Journal of Clinical Medicine
Wed Nov 13, 2019 02:00
Medicina, Vol. 55, Pages 735: Validity of Prediction Equations of Maximal Heart Rate in Physically Active Female Adolescents and the Role of Maturation
Medicina, Vol. 55, Pages 735: Validity of Prediction Equations of Maximal Heart Rate in Physically Active Female Adolescents and the Role of Maturation Medicina doi: 10.3390/medicina55110735 Authors: Papadopoulou Papadopoulou Alipasali Hatzimanouil Rosemann Knechtle Nikolaidis Background and objectives: Maximal heart rate (HRmax) is an important training and testing tool, especially in the context of evaluating intensity in exercise prescription; however, few...
Medicina
Wed Nov 13, 2019 02:00
Medicines, Vol. 6, Pages 110: Role of Dysregulated Ion Channels in Sensory Neurons in Chronic Kidney Disease-Associated Pruritus
Medicines, Vol. 6, Pages 110: Role of Dysregulated Ion Channels in Sensory Neurons in Chronic Kidney Disease-Associated Pruritus Medicines doi: 10.3390/medicines6040110 Authors: Akishi Momose Micihihiro Yabe Shigetoshi Chiba Kenjirou Kumakawa Yasuo Shiraiwa Hiroki Mizukami Background: We investigated ion channels at the skin, including peripheral nerve endings, which serve as output machines and molecular integrators of many pruritic inputs mainly received by multiple...
Medicines
Wed Nov 13, 2019 02:00
Membranes, Vol. 9, Pages 153: How Molecular Weight Cut-Offs and Physicochemical Properties of Polyether Sulfone Membranes Affect Peptide Migration and Selectivity during Electrodialysis with Filtration Membranes
Membranes, Vol. 9, Pages 153: How Molecular Weight Cut-Offs and Physicochemical Properties of Polyether Sulfone Membranes Affect Peptide Migration and Selectivity during Electrodialysis with Filtration Membranes Membranes doi: 10.3390/membranes9110153 Authors: Sabita Kadel Geneviève Pellerin Jacinthe Thibodeau Véronique Perreault Carole Lainé Laurent Bazinet Filtration membranes (FMs) are an integral part of electrodialysis with filtration membranes (EDFM), a green and...
Membranes
Wed Nov 13, 2019 02:00
Membranes, Vol. 9, Pages 152: Effect of Carbon Dioxide Loading on Removal of Heat Stable Salts from Amine Solvent by Electrodialysis
Membranes, Vol. 9, Pages 152: Effect of Carbon Dioxide Loading on Removal of Heat Stable Salts from Amine Solvent by Electrodialysis Membranes doi: 10.3390/membranes9110152 Authors: Evgeniia Grushevenko Stepan Bazhenov Vladimir Vasilevsky Eduard Novitsky Maxim Shalygin Alexey Volkov Heat stable salts (HSS) formed and continuously accumulated in the amine-based solvents due to solvent degradation and impurities in the feed gas can dramatically change the efficiency of the...
Membranes
Wed Nov 13, 2019 02:00
Metabolites, Vol. 9, Pages 279: Multi-Organ NMR Metabolomics to Assess In Vivo Overall Metabolic Impact of Cisplatin in Mice
Metabolites, Vol. 9, Pages 279: Multi-Organ NMR Metabolomics to Assess In Vivo Overall Metabolic Impact of Cisplatin in Mice Metabolites doi: 10.3390/metabo9110279 Authors: Tatiana J. Carneiro Rita Araújo Martin Vojtek Salomé Gonçalves-Monteiro Carmen Diniz Ana L.M. Batista de Carvalho Maria Paula M. Marques Ana M. Gil This work describes, to our knowledge, the first NMR metabolomics analysis of mice kidney, liver, and breast tissue in response to cisplatin exposure,...
Metabolites
Wed Nov 13, 2019 02:00
MPs, Vol. 2, Pages 85: Characterising Mutational Spectra of Carcinogens in the Tumour Suppressor Gene TP53 Using Human TP53 Knock-in (Hupki) Mouse Embryo Fibroblasts
MPs, Vol. 2, Pages 85: Characterising Mutational Spectra of Carcinogens in the Tumour Suppressor Gene TP53 Using Human TP53 Knock-in (Hupki) Mouse Embryo Fibroblasts Methods and Protocols doi: 10.3390/mps2040085 Authors: Hölzl-Armstrong Kucab Korenjak Luijten Phillips Zavadil Arlt DNA in dividing cells is prone to mutagenesis, with mutations making key contributions to human disease including cancer. The tumour suppressor gene TP53 is the most frequently mutated...
Methods and Protocols
Wed Nov 13, 2019 02:00
Microorganisms, Vol. 7, Pages 562: Perilla frutescens Leaf Alters the Rumen Microbial Community of Lactating Dairy Cows
Microorganisms, Vol. 7, Pages 562: Perilla frutescens Leaf Alters the Rumen Microbial Community of Lactating Dairy CowsMicroorganisms doi: 10.3390/microorganisms7110562Authors:Zhiqiang SunZhu YuBing WangPerilla frutescens (L.) Britt., an annual herbaceous plant, has antibacterial, anti-inflammation, and antioxidant properties. To understand the effects of P. frutescens leaf on the ruminal microbial ecology of cattle, Illumina MiSeq 16S rRNA sequencing technology was used. Fourteen cows were used...
Microorganisms
Wed Nov 13, 2019 02:00

Microorganisms, Vol. 7, Pages 561: Gut Bacteria and their Metabolites: Which One Is the Defendant for Colorectal Cancer?
Microorganisms, Vol. 7, Pages 561: Gut Bacteria and their Metabolites: Which One Is the Defendant for Colorectal Cancer?Microorganisms doi: 10.3390/microorganisms7110561Authors:Samira TarashiSeyed Davar SiadatSara Ahmadi BadiMohammadreza ZaliRoberto BiassoniMirco PonzoniArfa MoshiriColorectal cancer (CRC) is a worldwide health concern which requires efficient therapeutic strategies. The mechanisms underlying CRC remain an essential subject of investigations in the cancer biology field. The evaluation...
Microorganisms
Wed Nov 13, 2019 02:00
Microorganisms, Vol. 7, Pages 560: Analysis of the Indole Diterpene Gene Cluster for Biosynthesis of the Epoxy-Janthitrems in Epichloë Endophytes
Microorganisms, Vol. 7, Pages 560: Analysis of the Indole Diterpene Gene Cluster for Biosynthesis of the Epoxy-Janthitrems in Epichloë EndophytesMicroorganisms doi: 10.3390/microorganisms7110560Authors:Emma J. LudlowSimone VassiliadisPiyumi N. EkanayakeInoka K. HettiarachchigePriyanka ReddyTim I. SawbridgeSimone J. RochfortGerman C. SpangenbergKathryn M. GuthridgeEpoxy-janthitrems are a class of indole diterpenes with structural similarity to lolitrem B. Two taxa of asexual Epichloë endophytes...
Microorganisms
Wed Nov 13, 2019 02:00
Molecules, Vol. 24, Pages 4105: AC Electrodeposition of PEDOT Films in Protic Ionic Liquids for Long-Term Stable Organic Electrochemical Transistors
Molecules, Vol. 24, Pages 4105: AC Electrodeposition of PEDOT Films in Protic Ionic Liquids for Long-Term Stable Organic Electrochemical Transistors Molecules doi: 10.3390/molecules24224105 Authors: Jianlong Ji Xiaoxian Zhu Dan Han Mangmang Li Qiang Zhang Yang Shu Zhengdong Cheng Wendong Zhang Er Hua Shengbo Sang Poly(3,4-ethylenedioxythiophene):poly(4-styrenesulfonate) (PEDOT:PSS)-based organic electrochemical transistors (OECTs) are widely utilized to construct...
Molecules
02:00
Molecules, Vol. 24, Pages 4104: The Synergy of Ciprofloxacin and Carvedilol against Staphylococcus aureus–Prospects of a New Treatment Strategy?
Molecules, Vol. 24, Pages 4104: The Synergy of Ciprofloxacin and Carvedilol against Staphylococcus aureus–Prospects of a New Treatment Strategy? Molecules doi: 10.3390/molecules24224104 Authors: Katarzyna Zawadzka Marta Nowak Ireneusz Piwoński Katarzyna Lisowska Staphylococcus aureus infections are common and difficult to treat. The increasing number of drug-resistant staphylococcal infections has created the need to develop new strategies for the treatment of these infections....
Molecules
02:00
Molecules, Vol. 24, Pages 4103: Optimization of Scorpion Protein Extraction and Characterization of the Proteins’ Functional Properties
Molecules, Vol. 24, Pages 4103: Optimization of Scorpion Protein Extraction and Characterization of the Proteins’ Functional Properties Molecules doi: 10.3390/molecules24224103 Authors: Ahmidin Wali Atikan Wubulikasimu Sharafitdin Mirzaakhmedov Yanhua Gao Adil Omar Amina Arken Abulimiti Yili Haji Akber Aisa Scorpion has long been used in traditional Chinese medicine, because whole scorpion body extract has anti-cancer, analgesic, anti-thrombotic blood anti-coagulation,...
Molecules
Wed Nov 13, 2019 02:00
Molecules, Vol. 24, Pages 4102: Synthesis and Electrochemical and Spectroscopic Characterization of 4,7-diamino-1,10-phenanthrolines and Their Precursors
Molecules, Vol. 24, Pages 4102: Synthesis and Electrochemical and Spectroscopic Characterization of 4,7-diamino-1,10-phenanthrolines and Their Precursors Molecules doi: 10.3390/molecules24224102 Authors: Nycz Wantulok Sokolova Pajchel Stankevič Szala Malecki Swoboda New approaches to the synthesis of 4,7-dichloro-1,10-phenanthrolines and their corresponding 9H-carbazol-9-yl-, 10H-phenothiazin-10-yl- and pyrrolidin-1-yl derivatives were developed. Their properties...
Molecules
Wed Nov 13, 2019 02:00
Molecules, Vol. 24, Pages 4101: Possible Mechanisms of Biological Effects Observed in Living Systems during 2H/1H Isotope Fractionation and Deuterium Interactions with Other Biogenic Isotopes
Molecules, Vol. 24, Pages 4101: Possible Mechanisms of Biological Effects Observed in Living Systems during 2H/1H Isotope Fractionation and Deuterium Interactions with Other Biogenic Isotopes Molecules doi: 10.3390/molecules24224101 Authors: Alexander Basov Liliya Fedulova Ekaterina Vasilevskaya Stepan Dzhimak This article presents the original descriptions of some recent physics mechanisms (based on the thermodynamic, kinetic, and quantum tunnel effects) providing stable 2H/1H...
Molecules
Wed Nov 13, 2019 02:00
Molecules, Vol. 24, Pages 4099: Improving Water Permeability of Hydrophilic PVDF Membrane Prepared via Blending with Organic and Inorganic Additives for Humic Acid Separation
Molecules, Vol. 24, Pages 4099: Improving Water Permeability of Hydrophilic PVDF Membrane Prepared via Blending with Organic and Inorganic Additives for Humic Acid Separation Molecules doi: 10.3390/molecules24224099 Authors: Nasrul Arahman Sri Mulyati Afrillia Fahrina Syawaliah Muchtar Mukramah Yusuf Ryosuke Takagi Hideto Matsuyama Nik Abdul Hadi Nordin Muhammad Roil Bilad The removal of impurities from water or wastewater by the membrane filtration process has...
Molecules
Wed Nov 13, 2019 02:00
Molecules, Vol. 24, Pages 4098: Rapid Analysis of the Chemical Compositions in Semiliquidambar cathayensis Roots by Ultra High-Performance Liquid Chromatography and Quadrupole Time-of-Flight Tandem Mass Spectrometry
Molecules, Vol. 24, Pages 4098: Rapid Analysis of the Chemical Compositions in Semiliquidambar cathayensis Roots by Ultra High-Performance Liquid Chromatography and Quadrupole Time-of-Flight Tandem Mass Spectrometry Molecules doi: 10.3390/molecules24224098 Authors: Li Yang Rong-Hua Liu Jun-Wei He Semiliquidambar cathayensis Chang was a traditional medicinal plant and used to treat rheumatism arthritis and rheumatic arthritis for centuries in China with no scientific validation,...
Molecules
Wed Nov 13, 2019 02:00
Molecules, Vol. 24, Pages 4100: Dicentrine Potentiates TNF-α-Induced Apoptosis and Suppresses Invasion of A549 Lung Adenocarcinoma Cells via Modulation of NF-κB and AP-1 Activation
Molecules, Vol. 24, Pages 4100: Dicentrine Potentiates TNF-α-Induced Apoptosis and Suppresses Invasion of A549 Lung Adenocarcinoma Cells via Modulation of NF-κB and AP-1 Activation Molecules doi: 10.3390/molecules24224100 Authors: Chanatip Ooppachai Pornngarm Limtrakul (Dejkriengkraikul) Supachai Yodkeeree Numerous studies have indicated that tumor necrosis factor-alpha (TNF-α) could induce cancer cell survival and metastasis via activation of transcriptional activity...
Molecules
Wed Nov 13, 2019 02:00
Molecules, Vol. 24, Pages 4097: Synthesis and Anticancer Activity of CDDO and CDDO-Me, Two Derivatives of Natural Triterpenoids
Molecules, Vol. 24, Pages 4097: Synthesis and Anticancer Activity of CDDO and CDDO-Me, Two Derivatives of Natural Triterpenoids Molecules doi: 10.3390/molecules24224097 Authors: Rebecca Borella Luca Forti Lara Gibellini Anna De Gaetano Sara De Biasi Milena Nasi Andrea Cossarizza Marcello Pinti Triterpenoids are natural compounds synthesized by plants through cyclization of squalene, known for their weak anti-inflammatory activity. 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic...
Molecules
Wed Nov 13, 2019 02:00
Molecules, Vol. 24, Pages 4096: Grafting versus Crosslinking of Silk Fibroin-g-PNIPAM via Tyrosine-NIPAM Bridges
Molecules, Vol. 24, Pages 4096: Grafting versus Crosslinking of Silk Fibroin-g-PNIPAM via Tyrosine-NIPAM Bridges Molecules doi: 10.3390/molecules24224096 Authors: Ionut-Cristian Radu Iuliana-Elena Biru Celina-Maria Damian Andreea-Cristina Ion Horia Iovu Eugenia Tanasa Catalin Zaharia Bianca Galateanu This paper reports the synthesis and complex characterization of novel polymeric networks based on the crosslinking of Bombyx mori silk fibroin via poly(N-isopropylacrylamide)...
Molecules
Wed Nov 13, 2019 02:00
Molecules, Vol. 24, Pages 4095: The Development of Novel Compounds Against Malaria: Quinolines, Triazolpyridines, Pyrazolopyridines and Pyrazolopyrimidines
Molecules, Vol. 24, Pages 4095: The Development of Novel Compounds Against Malaria: Quinolines, Triazolpyridines, Pyrazolopyridines and Pyrazolopyrimidines Molecules doi: 10.3390/molecules24224095 Authors: Luiz C. S. Pinheiro Lívia M. Feitosa Marilia O. Gandi Flávia F. Silveira Nubia Boechat Based on medicinal chemistry tools, new compounds for malaria treatment were designed. The scaffolds of the drugs used to treat malaria, such as chloroquine, primaquine, amodiaquine,...
Molecules
Wed Nov 13, 2019 02:00
Molecules, Vol. 24, Pages 4091: Raman Spectroscopy and Chemometric Modeling to Predict Physical-Chemical Honey Properties from Campeche, Mexico
Molecules, Vol. 24, Pages 4091: Raman Spectroscopy and Chemometric Modeling to Predict Physical-Chemical Honey Properties from Campeche, Mexico Molecules doi: 10.3390/molecules24224091 Authors: F. Anguebes-Franseschi M. Abatal Lucio Pat A. Flores A. V. Córdova Quiroz M. A. Ramírez-Elias L. San Pedro O. May Tzuc A. Bassam In this work, 10 chemometric models based on Raman spectroscopy were constructed to predict the physicochemical properties of honey produced...
Molecules
Wed Nov 13, 2019 02:00
Molecules, Vol. 24, Pages 4094: Kinetic Modelling of [68Ga]Ga-DOTA-Siglec-9 in Porcine Osteomyelitis and Soft Tissue Infections
Molecules, Vol. 24, Pages 4094: Kinetic Modelling of [68Ga]Ga-DOTA-Siglec-9 in Porcine Osteomyelitis and Soft Tissue Infections Molecules doi: 10.3390/molecules24224094 Authors: Lars Jødal Anne Roivainen Vesa Oikonen Sirpa Jalkanen Søren B. Hansen Pia Afzelius Aage K. O. Alstrup Ole L. Nielsen Svend B. Jensen Background: [68Ga]Ga-DOTA-Siglec-9 is a positron emission tomography (PET) radioligand for vascular adhesion protein 1 (VAP-1), a protein involved in leukocyte...
Molecules
Wed Nov 13, 2019 02:00
MTI, Vol. 3, Pages 73: Audio Legends: Investigating Sonic Interaction in an Augmented Reality Audio Game
MTI, Vol. 3, Pages 73: Audio Legends: Investigating Sonic Interaction in an Augmented Reality Audio Game Multimodal Technologies and Interaction doi: 10.3390/mti3040073 Authors: Emmanouel Rovithis Nikolaos Moustakas Andreas Floros Kostas Vogklis Augmented Reality Audio Games (ARAG) enrich the physical world with virtual sounds to express their content and mechanics. Existing ARAG implementations have focused on exploring the surroundings and navigating to virtual sound sources...
Multimodal Technologies and Interaction
Wed Nov 13, 2019 02:00
Nanomaterials, Vol. 9, Pages 1612: Polyimide-Coated Glass Microfiber as Polysulfide Perm-Selective Separator for High-Performance Lithium-Sulphur Batteries
Nanomaterials, Vol. 9, Pages 1612: Polyimide-Coated Glass Microfiber as Polysulfide Perm-Selective Separator for High-Performance Lithium-Sulphur Batteries Nanomaterials doi: 10.3390/nano9111612 Authors: Mi-Jin Kim Kwansoo Yang Hui-Ju Kang Hyun Jin Hwang Jong Chan Won Yun Ho Kim Young-Si Jun Although numerous research efforts have been made for the last two decades, the chronic problems of lithium-sulphur batteries (LSBs), i.e., polysulfide shuttling of active sulphur...
Nanomaterials
Wed Nov 13, 2019 02:00
Nanomaterials, Vol. 9, Pages 1610: Polymerization-Induced Phase Segregation and Self-Assembly of Siloxane Additives to Provide Thermoset Coatings with a Defined Surface Topology and Biocidal and Self-Cleaning Properties
Nanomaterials, Vol. 9, Pages 1610: Polymerization-Induced Phase Segregation and Self-Assembly of Siloxane Additives to Provide Thermoset Coatings with a Defined Surface Topology and Biocidal and Self-Cleaning Properties Nanomaterials doi: 10.3390/nano9111610 Authors: Jaleh Mansouri Vi Khanh Truong Shane MacLaughlin David E. Mainwaring Graeme Moad Ian J. Dagley Elena P. Ivanova Russell J. Crawford Vicki Chen In this work, we report on the incorporation of a siloxane...
Nanomaterials
Wed Nov 13, 2019 02:00
Nanomaterials, Vol. 9, Pages 1611: Co2TiO4/Reduced Graphene Oxide Nanohybrids for Electrochemical Sensing Applications
Nanomaterials, Vol. 9, Pages 1611: Co2TiO4/Reduced Graphene Oxide Nanohybrids for Electrochemical Sensing Applications Nanomaterials doi: 10.3390/nano9111611 Authors: Constanza J. Venegas Fabiana A. Gutierrez Marcos Eguílaz José F. Marco Nik Reeves-McLaren Gustavo A. Rivas Domingo Ruiz-León Soledad Bollo For the first time, the synthesis, characterization, and analytical application for hydrogen peroxide quantification of the hybrid materials of Co2TiO4 (CTO) and...
Nanomaterials
Wed Nov 13, 2019 02:00
Nanomaterials, Vol. 9, Pages 1609: Effects of Divacancy and Extended Line Defects on the Thermal Transport Properties of Graphene Nanoribbons
Nanomaterials, Vol. 9, Pages 1609: Effects of Divacancy and Extended Line Defects on the Thermal Transport Properties of Graphene Nanoribbons Nanomaterials doi: 10.3390/nano9111609 Authors: Min Luo Bo-Lin Li Dengfeng Li The effects of divacancy, including isolated defects and extended line defects (ELD), on the thermal transport properties of graphene nanoribbons (GNRs) are investigated using the Nonequilibrium Green’s function method. Different divacancy defects can...
Nanomaterials
Wed Nov 13, 2019 02:00

Nutrients, Vol. 11, Pages 2757: Association between Iodine Nutrition Status and Thyroid Disease-Related Hormone in Korean Adults: Korean National Health and Nutrition Examination Survey VI (2013–2015)
Nutrients, Vol. 11, Pages 2757: Association between Iodine Nutrition Status and Thyroid Disease-Related Hormone in Korean Adults: Korean National Health and Nutrition Examination Survey VI (2013–2015) Nutrients doi: 10.3390/nu11112757 Authors: Kim Kwon Kim Hong Park This study aimed to observe the relationship between iodine nutrition status (dietary iodine intake and estimated iodine intake based on urinary iodine concentration (UIC)) and thyroid disease-related hormones....
Nutrients
Wed Nov 13, 2019 02:00
Nutrients, Vol. 11, Pages 2758: Natural Choline from Egg Yolk Phospholipids Is More Efficiently Absorbed Compared with Choline Bitartrate; Outcomes of A Randomized Trial in Healthy Adults
Nutrients, Vol. 11, Pages 2758: Natural Choline from Egg Yolk Phospholipids Is More Efficiently Absorbed Compared with Choline Bitartrate; Outcomes of A Randomized Trial in Healthy Adults Nutrients doi: 10.3390/nu11112758 Authors: Lotte Smolders Nicole J.W. de Wit Michiel G.J. Balvers Rima Obeid Marc M.M. Vissers Diederik Esser Choline is a vitamin-like essential nutrient, important throughout one’s lifespan. Therefore, choline salts are added to infant formula,...
Nutrients
Wed Nov 13, 2019 02:00
Nutrients, Vol. 11, Pages 2756: Effect of Micronutrient Powder (MNP) with a Low-Dose of Iron on Hemoglobin and Iron Biomarkers, and Its Effect on Morbidities in Rural Bangladeshi Children Drinking Groundwater with a High-Level of Iron: A Randomized Controlled Trial
Nutrients, Vol. 11, Pages 2756: Effect of Micronutrient Powder (MNP) with a Low-Dose of Iron on Hemoglobin and Iron Biomarkers, and Its Effect on Morbidities in Rural Bangladeshi Children Drinking Groundwater with a High-Level of Iron: A Randomized Controlled Trial Nutrients doi: 10.3390/nu11112756 Authors: Sabuktagin Rahman Patricia Lee Rubhana Raqib Anjan K. Roy Moududur R. Khan Faruk Ahmed Micronutrient Powder (MNP) is beneficial to control anemia, but some iron-related...
Nutrients
Wed Nov 13, 2019 02:00
Nutrients, Vol. 11, Pages 2755: Mumefural Ameliorates Cognitive Impairment in Chronic Cerebral Hypoperfusion via Regulating the Septohippocampal Cholinergic System and Neuroinflammation
Nutrients, Vol. 11, Pages 2755: Mumefural Ameliorates Cognitive Impairment in Chronic Cerebral Hypoperfusion via Regulating the Septohippocampal Cholinergic System and Neuroinflammation Nutrients doi: 10.3390/nu11112755 Authors: Jihye Bang Min-Soo Kim Won Kyung Jeon Chronic cerebral hypoperfusion (CCH) causes cognitive impairment and neurogenic inflammation by reducing blood flow. We previously showed that Fructus mume (F. mume) improves cognitive impairment and inhibits neuroinflammation...
Nutrients
Wed Nov 13, 2019 02:00
Nutrients, Vol. 11, Pages 2753: Dietary Patterns and the Double Burden of Malnutrition in Mexican Adolescents: Results from ENSANUT-2006
Nutrients, Vol. 11, Pages 2753: Dietary Patterns and the Double Burden of Malnutrition in Mexican Adolescents: Results from ENSANUT-2006 Nutrients doi: 10.3390/nu11112753 Authors: Arli Guadalupe Zárate-Ortiz Alida Melse-Boonstra Sonia Rodríguez-Ramírez Sonia Hernández-Cordero Edith J. M. Feskens Mexico is facing the double burden of malnutrition, and adolescents are not an exception. Diet plays an important role, both in causing overweight and undernutrition. This study aimed...
Nutrients
Wed Nov 13, 2019 02:00
Nutrients, Vol. 11, Pages 2754: New Zealand Bitter Hops Extract Reduces Hunger During a 24 h Water Only Fast
Nutrients, Vol. 11, Pages 2754: New Zealand Bitter Hops Extract Reduces Hunger During a 24 h Water Only Fast Nutrients doi: 10.3390/nu11112754 Authors: Edward Walker Kim Lo Sze Tham Malcolm Pahl Dominic Lomiwes Janine Cooney Mark Wohlers Pramod Gopal Intermittent fasting improves metabolic and cardiac health. However, increased hunger towards the end of the fasting period may affect compliance and limit its application. Our aim was to determine the effect of anorexigenic...
Nutrients
Wed Nov 13, 2019 02:00
Nutrients, Vol. 11, Pages 2752: Associations of Less Healthy Snack Food Consumption with Infant Weight-for-Length Z-Score Trajectories: Findings from the Nurture Cohort Study
Nutrients, Vol. 11, Pages 2752: Associations of Less Healthy Snack Food Consumption with Infant Weight-for-Length Z-Score Trajectories: Findings from the Nurture Cohort Study Nutrients doi: 10.3390/nu11112752 Authors: Amy M. Moore Maya Vadiveloo Alison Tovar Karen McCurdy Truls Østbye Sara E. Benjamin-Neelon Little is known about the impact of less healthy snack foods on weight trajectories during infancy. This secondary analysis of data from the Nurture cohort explored...
Nutrients
Wed Nov 13, 2019 02:00
Nutrients, Vol. 11, Pages 2751: Candidate Gene and Genome-Wide Association Studies for Circulating Leptin Levels Reveal Population and Sex-Specific Associations in High Cardiovascular Risk Mediterranean Subjects
Nutrients, Vol. 11, Pages 2751: Candidate Gene and Genome-Wide Association Studies for Circulating Leptin Levels Reveal Population and Sex-Specific Associations in High Cardiovascular Risk Mediterranean Subjects Nutrients doi: 10.3390/nu11112751 Authors: Carolina Ortega-Azorín Oscar Coltell Eva M. Asensio Jose V. Sorlí José I. González Olga Portolés Carmen Saiz Ramon Estruch Judith B Ramírez-Sabio Alejandro Pérez-Fidalgo Jose M Ordovas Dolores Corella Leptin...
Nutrients
Wed Nov 13, 2019 02:00
Pathogens, Vol. 8, Pages 235: A GntR Family Transcription Factor (VPA1701) for Swarming Motility and Colonization of Vibrio parahaemolyticus
Pathogens, Vol. 8, Pages 235: A GntR Family Transcription Factor (VPA1701) for Swarming Motility and Colonization of Vibrio parahaemolyticus Pathogens doi: 10.3390/pathogens8040235 Authors: Dan Gu Hongmei Meng Yang Li Haojie Ge Xinan Jiao Motility is important for virulence, biofilm formation, and the environmental adaptation of many bacteria. Vibrio parahaemolyticus (V. parahaemolyticus) contains two flagellar systems that are responsible for motility, and are tightly regulated...
Pathogens
Wed Nov 13, 2019 02:00
Pathogens, Vol. 8, Pages 234: Porcine Alveolar Macrophages’ Nitric Oxide Synthase-Mediated Generation of Nitric Oxide Exerts Important Defensive Effects against Glaesserella parasuis Infection
Pathogens, Vol. 8, Pages 234: Porcine Alveolar Macrophages’ Nitric Oxide Synthase-Mediated Generation of Nitric Oxide Exerts Important Defensive Effects against Glaesserella parasuis Infection Pathogens doi: 10.3390/pathogens8040234 Authors: Qi Cao Huan Wang Wenbin Wei Yujin Lv Zhao Wen Xiaojuan Xu Xuwang Cai Huanchun Chen Xiangru Wang Glaesserella parasuis is a habitual bacterium of pigs’ upper respiratory tracts. Its infection initiates with the invasion...
Pathogens
Wed Nov 13, 2019 02:00
Pharmaceutics, Vol. 11, Pages 608: An Effective Cationic Human Serum Albumin-based Gene-Delivery Carrier Containing the Nuclear Localization Signal
Pharmaceutics, Vol. 11, Pages 608: An Effective Cationic Human Serum Albumin-based Gene-Delivery Carrier Containing the Nuclear Localization Signal Pharmaceutics doi: 10.3390/pharmaceutics11110608 Authors: Guan Song Zhang Chen Hu Wang Chen Considerable effort has been devoted to the development of gene carriers over the years. However, toxicity, immunogenicity, and low transfection efficiency are still major barriers. How to overcome these obstacles has become...
Pharmaceutics
Wed Nov 13, 2019 02:00
Pharmaceutics, Vol. 11, Pages 609: Preparation and Evaluation of Atorvastatin-Loaded Nanoemulgel on Wound-Healing Efficacy
Pharmaceutics, Vol. 11, Pages 609: Preparation and Evaluation of Atorvastatin-Loaded Nanoemulgel on Wound-Healing Efficacy Pharmaceutics doi: 10.3390/pharmaceutics11110609 Authors: Morsy Abdel-Latif Nair Venugopala Ahmed Elsewedy Shehata Tissue repair and wound healing are complex processes that involve inflammation, granulation, and remodeling of the tissue. The potential of various statins including atorvastatin (ATR) to improve the wound healing effect was...
Pharmaceutics
Wed Nov 13, 2019 02:00
Pharmaceutics, Vol. 11, Pages 607: Evaluation of Skin Permeation and Retention of Topical Dapsone in Murine Cutaneous Leishmaniasis Lesions
Pharmaceutics, Vol. 11, Pages 607: Evaluation of Skin Permeation and Retention of Topical Dapsone in Murine Cutaneous Leishmaniasis Lesions Pharmaceutics doi: 10.3390/pharmaceutics11110607 Authors: Moreno Calvo Schwartz Navarro-Blasco González-Peñas Sanmartín Irache Espuelas The oral administration of dapsone (DAP) for the treatment of cutaneous leishmaniasis (CL) is effective, although serious hematological side effects limit its use. In this study, we evaluated...
Pharmaceutics
Wed Nov 13, 2019 02:00
Pharmaceutics, Vol. 11, Pages 606: Enhancement in Site-Specific Delivery of Carvacrol against Methicillin Resistant Staphylococcus aureus Induced Skin Infections Using Enzyme Responsive Nanoparticles: A Proof of Concept Study
Pharmaceutics, Vol. 11, Pages 606: Enhancement in Site-Specific Delivery of Carvacrol against Methicillin Resistant Staphylococcus aureus Induced Skin Infections Using Enzyme Responsive Nanoparticles: A Proof of Concept Study Pharmaceutics doi: 10.3390/pharmaceutics11110606 Authors: Maria Mir Naveed Ahmed Andi Dian Permana Aoife Maria Rodgers Ryan F. Donnelly Asim.ur. Rehman Methicillin resistant Staphylococcus aureus (MRSA) induced skin infections have become a challenging...
Pharmaceutics
Wed Nov 13, 2019 02:00
Pharmaceutics, Vol. 11, Pages 604: Design and Evaluation of pH-Dependent Nanosystems Based on Cellulose Acetate Phthalate, Nanoparticles Loaded with Chlorhexidine for Periodontal Treatment
Pharmaceutics, Vol. 11, Pages 604: Design and Evaluation of pH-Dependent Nanosystems Based on Cellulose Acetate Phthalate, Nanoparticles Loaded with Chlorhexidine for Periodontal Treatment Pharmaceutics doi: 10.3390/pharmaceutics11110604 Authors: Gustavo Vidal-Romero María L. Zambrano-Zaragoza Lizbeth Martínez-Acevedo Gerardo Leyva-Gómez Susana E. Mendoza-Elvira David Quintanar-Guerrero This work aimed to develop and evaluate pH-dependent systems based on nanospheres (NSphs)...
Pharmaceutics
Wed Nov 13, 2019 02:00
Pharmaceutics, Vol. 11, Pages 605: Design and Development of Liquid Drug Reservoirs for Microneedle Delivery of Poorly Soluble Drug Molecules
Pharmaceutics, Vol. 11, Pages 605: Design and Development of Liquid Drug Reservoirs for Microneedle Delivery of Poorly Soluble Drug Molecules Pharmaceutics doi: 10.3390/pharmaceutics11110605 Authors: Mary-Carmel Kearney Peter E. McKenna Helen L. Quinn Aaron J. Courtenay Eneko Larrañeta Ryan F. Donnelly The poor aqueous solubility of existing and emerging drugs is a major issue faced by the pharmaceutical industry. Water-miscible organic solvents, termed co-solvents, can...
Pharmaceutics
Wed Nov 13, 2019 02:00
Pharmacy, Vol. 7, Pages 153: Clinical Pharmacy Intervention for Persons Experiencing Homelessness: Evaluation of Patient Perspectives in Service Design and Development
Pharmacy, Vol. 7, Pages 153: Clinical Pharmacy Intervention for Persons Experiencing Homelessness: Evaluation of Patient Perspectives in Service Design and Development Pharmacy doi: 10.3390/pharmacy7040153 Authors: Parbir Jagpal Nigel Barnes Richard Lowrie Amitava Banerjee Vibhu Paudyal Persons experiencing homelessness have a high prevalence of severe mental health problems, alcohol dependence, substance misuse and infectious hepatitis C, and face up to twelve times higher...
Pharmacy
Wed Nov 13, 2019 02:00
Plants, Vol. 8, Pages 499: Glyphosate: Its Environmental Persistence and Impact on Crop Health and Nutrition
Plants, Vol. 8, Pages 499: Glyphosate: Its Environmental Persistence and Impact on Crop Health and Nutrition Plants doi: 10.3390/plants8110499 Authors: Ramdas Kanissery Biwek Gairhe Davie Kadyampakeni Ozgur Batuman Fernando Alferez Glyphosate-based herbicide products are the most widely used broad-spectrum herbicides in the world for postemergent weed control. There are ever-increasing concerns that glyphosate, if not used judiciously, may cause adverse nontarget impacts...
Plants
Wed Nov 13, 2019 02:00
Religions, Vol. 10, Pages 628: The Samaritans during the Hasmonean Period: The Affirmation of a Discrete Identity?
Religions, Vol. 10, Pages 628: The Samaritans during the Hasmonean Period: The Affirmation of a Discrete Identity? Religions doi: 10.3390/rel10110628 Authors: Jonathan Bourgel The Hasmonean period (167–63 BCE) is increasingly seen in current scholarship as formative for Samaritan identity and, in particular, as the moment when the Samaritans emerged as a self-contained group separate from the Jews. The first aim of this paper is to give an overview of the condition of the Samaritans...
Religions
02:00
Robotics, Vol. 8, Pages 96: Quantifying Age-Related Differences of Ankle Mechanical Properties Using a Robotic Device
Robotics, Vol. 8, Pages 96: Quantifying Age-Related Differences of Ankle Mechanical Properties Using a Robotic Device Robotics doi: 10.3390/robotics8040096 Authors: Martelli Taborri Del Prete Palermo Rossi A deep analysis of ankle mechanical properties is a fundamental step in the design of an exoskeleton, especially if it is to be suitable for both adults and children. This study aims at assessing age-related differences of ankle properties using pediAnklebot. To achieve...
Robotics
Wed Nov 13, 2019 02:00

Sci, Vol. 1, Pages 24: Power Laws and Elementary Particle Decays
Sci, Vol. 1, Pages 24: Power Laws and Elementary Particle Decays Sci doi: 10.3390/sci1030024 Authors: Chiatti This study analyzes the correlation between the lifetime and the rest energy of the unstableparticle states with a lifetime greater than the zeptosecond (10−21 s), using data available from theParticle Data Group. This set of states seems to be divided into three groups, in each of which the twoquantities can be correlated through a remarkably accurate power law. Although...
Sci
Wed Nov 13, 2019 02:00
Social Sciences, Vol. 8, Pages 313: Compassion Fatigue and Vicarious Trauma in Everyday Hospital Social Work: A Personal Narrative of Practitioner–Researcher Identity Transition
Social Sciences, Vol. 8, Pages 313: Compassion Fatigue and Vicarious Trauma in Everyday Hospital Social Work: A Personal Narrative of Practitioner–Researcher Identity Transition Social Sciences doi: 10.3390/socsci8110313 Authors: Fox The story of my evolution as a practice-based collaborative researcher is a story that comes full circle. Through exploring my own experiences of compassion fatigue and vicarious trauma as a hospital-based social worker, I am able to investigate the phenomenon...
Social Sciences
Wed Nov 13, 2019 02:00
Social Sciences, Vol. 8, Pages 312: Fathers’ Parental Leave Uptake in Belgium and Sweden: Self-Evident or Subject to Employment Characteristics?
Social Sciences, Vol. 8, Pages 312: Fathers’ Parental Leave Uptake in Belgium and Sweden: Self-Evident or Subject to Employment Characteristics? Social Sciences doi: 10.3390/socsci8110312 Authors: Leen Marynissen Eleonora Mussino Jonas Wood Ann-Zofie Duvander The limited increase in fathers’ involvement in childcare tasks in response to the unprecedented rise in female labour market participation illustrates the incomplete nature of the gender revolution. Available...
Social Sciences
Wed Nov 13, 2019 02:00
Toxins, Vol. 11, Pages 660: Hemolysis Derived Products Toxicity and Endothelium: Model of the Second Hit
Toxins, Vol. 11, Pages 660: Hemolysis Derived Products Toxicity and Endothelium: Model of the Second Hit Toxins doi: 10.3390/toxins11110660 Authors: Marie Frimat Idris Boudhabhay Lubka Roumenina Vascular diseases are multifactorial, often requiring multiple challenges, or ‘hits’, for their initiation. Intra-vascular hemolysis illustrates well the multiple-hit theory where a first event lyses red blood cells, releasing hemolysis-derived products, in particular cell-free heme which...
Toxins
Wed Nov 13, 2019 02:00
Vaccines, Vol. 7, Pages 181: A PBMC-Based System to Assess Human T Cell Responses to Influenza Vaccine Candidates In Vitro
Vaccines, Vol. 7, Pages 181: A PBMC-Based System to Assess Human T Cell Responses to Influenza Vaccine Candidates In Vitro Vaccines doi: 10.3390/vaccines7040181 Authors: Gabriela Tapia-Calle Philip A. Born Georgia Koutsoumpli Martin Ignacio Gonzalez-Rodriguez Wouter L. J. Hinrichs Anke L. W. Huckriede Vaccine development is an expensive and time-consuming process that heavily relies on animal models. Yet, vaccine candidates that have previously succeeded in animal experiments...
Vaccines
Wed Nov 13, 2019 02:00
Veterinary Sciences, Vol. 6, Pages 91: The Role of Phosphatidylinositol Mannosides in the Serological Diagnosis of Mycobacterial Infections
Veterinary Sciences, Vol. 6, Pages 91: The Role of Phosphatidylinositol Mannosides in the Serological Diagnosis of Mycobacterial Infections Veterinary Sciences doi: 10.3390/vetsci6040091 Authors: Ad P. Koets Marielle H. van den Esker Karel Riepema Douwe Bakker Accurate diagnosis of mycobacterial infections, such as bovine tuberculosis and paratuberculosis, remains challenging. Available direct diagnostic tests aimed at detecting the pathogen are highly specific but lack sensitivity,...
Veterinary Sciences
Wed Nov 13, 2019 02:00
Viruses, Vol. 11, Pages 1055: PCV2 Regulates Cellular Inflammatory Responses through Dysregulating Cellular miRNA-mRNA Networks
Viruses, Vol. 11, Pages 1055: PCV2 Regulates Cellular Inflammatory Responses through Dysregulating Cellular miRNA-mRNA Networks Viruses doi: 10.3390/v11111055 Authors: Chang Li Yumei Sun Jing Li Changsheng Jiang Wei Zeng Hao Zhang Shengxian Fan Qigai He Porcine circovirus type 2 (PCV2) is closely linked to postweaning multisystemic wasting syndrome (PMWS) and other PCV-associated diseases (PCVADs), which influence the global pig industry. MicroRNAs (miRNAs) are evolutionarily...
Viruses
Wed Nov 13, 2019 02:00
Viruses, Vol. 11, Pages 1054: Delmarva (DMV/1639) Infectious Bronchitis Virus (IBV) Variants Isolated in Eastern Canada Show Evidence of Recombination
Viruses, Vol. 11, Pages 1054: Delmarva (DMV/1639) Infectious Bronchitis Virus (IBV) Variants Isolated in Eastern Canada Show Evidence of Recombination Viruses doi: 10.3390/v11111054 Authors: Mohamed S. H. Hassan Davor Ojkic Carla S. Coffin Susan C. Cork Frank van der Meer Mohamed Faizal Abdul-Careem Infectious bronchitis virus (IBV) infection in chickens can lead to an economically important disease, namely, infectious bronchitis (IB). New IBV variants are continuously...
Viruses
Wed Nov 13, 2019 02:00
Viruses, Vol. 11, Pages 1053: New Insights into Parvovirus Research
Viruses, Vol. 11, Pages 1053: New Insights into Parvovirus Research Viruses doi: 10.3390/v11111053 Authors: Giorgio Gallinella The family Parvoviridae includes an ample and most diverse collection of viruses. Exploring the biological diversity and the inherent complexity in these apparently simple viruses has been a continuous commitment for the scientific community since their first discovery more than fifty years ago. The Special Issue of ‘Viruses’ dedicated to...
Viruses
Wed Nov 13, 2019 02:00
Viruses, Vol. 11, Pages 1052: Characterization of Brain Inflammation, Apoptosis, Hypoxia, Blood-Brain Barrier Integrity and Metabolism in Venezuelan Equine Encephalitis Virus (VEEV TC-83) Exposed Mice by In Vivo Positron Emission Tomography Imaging
Viruses, Vol. 11, Pages 1052: Characterization of Brain Inflammation, Apoptosis, Hypoxia, Blood-Brain Barrier Integrity and Metabolism in Venezuelan Equine Encephalitis Virus (VEEV TC-83) Exposed Mice by In Vivo Positron Emission Tomography Imaging Viruses doi: 10.3390/v11111052 Authors: Thomas M. Bocan Robert G. Stafford Jennifer L. Brown Justice Akuoku Frimpong Falguni Basuli Bradley S. Hollidge Xiang Zhang Natarajan Raju Rolf E. Swenson Darci R. Smith Traditional...
Viruses
Wed Nov 13, 2019 02:00
Water, Vol. 11, Pages 2378: Model Performance Indicator of Aging Pipes in a Domestic Water Supply Distribution Network
Water, Vol. 11, Pages 2378: Model Performance Indicator of Aging Pipes in a Domestic Water Supply Distribution Network Water doi: 10.3390/w11112378 Authors: Norzaura Abd Rahman Nur Shazwani Muhammad Jazuri Abdullah Wan Hanna Melini Wan Mohtar Aging pipes in the domestic water distribution network have the potential to decrease the quality and quantity of the treated water supplied to the consumers. Therefore, a calibrated water distribution model is helpful to monitor and understand...
Water
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Water, Vol. 11, Pages 2377: Climate Change Impact Assessment on Freshwater Inflow into the Small Aral Sea
Water, Vol. 11, Pages 2377: Climate Change Impact Assessment on Freshwater Inflow into the Small Aral Sea Water doi: 10.3390/w11112377 Authors: Georgy Ayzel Alexander Izhitskiy During the last few decades, the rapid separation of the Small Aral Sea from the isolated basin has changed its hydrological and ecological conditions tremendously. In the present study, we developed and validated the hybrid model for the Syr Darya River basin based on a combination of state-of-the-art hydrological...
Water
Wed Nov 13, 2019 02:00
Water, Vol. 11, Pages 2374: Financial Benefits of Mangroves for Surge Prone High-Value Areas
Water, Vol. 11, Pages 2374: Financial Benefits of Mangroves for Surge Prone High-Value Areas Water doi: 10.3390/w11112374 Authors: Henk Jan Verhagen In this paper, protection options for a high-value, industrial area along the coast of West Bengal (India) are investigated. The options are designed to protect against cyclone surges with a probability of 1/100 per year. Two alternatives are compared, a classical solution of a dike with a revetment and a solution with a mangrove belt in...
Water
Wed Nov 13, 2019 02:00
Water, Vol. 11, Pages 2375: Assessment of Changes in Annual Maximum Precipitations in the Iberian Peninsula under Climate Change
Water, Vol. 11, Pages 2375: Assessment of Changes in Annual Maximum Precipitations in the Iberian Peninsula under Climate Change Water doi: 10.3390/w11112375 Authors: Carlos Garijo Luis Mediero Climate model projections can be used to assess the future expected behavior of extreme precipitation due to climate change. In Europe, the EURO-CORDEX project provides precipitation projections in the future under various representative concentration pathways (RCP), through regionalized outputs...
Water
Wed Nov 13, 2019 02:00
Water, Vol. 11, Pages 2376: Principal Component Weighted Index for Wastewater Quality Monitoring
Water, Vol. 11, Pages 2376: Principal Component Weighted Index for Wastewater Quality Monitoring Water doi: 10.3390/w11112376 Authors: Petr Praus The quality of raw and treated wastewater was evaluated using the principal component weighted index (PCWI) which was defined as a sum of principal component scores weighted according to their eigenvalues. For this purpose, five principal components (PCs) explaining 88% and 83% of the total variability of raw and treated wastewater samples,...
Water
Wed Nov 13, 2019 02:00
Water, Vol. 11, Pages 2372: Effect of the Surface Charge on the Adsorption Capacity of Chromium(VI) of Iron Oxide Magnetic Nanoparticles Prepared by Microwave-Assisted Synthesis
Water, Vol. 11, Pages 2372: Effect of the Surface Charge on the Adsorption Capacity of Chromium(VI) of Iron Oxide Magnetic Nanoparticles Prepared by Microwave-Assisted Synthesis Water doi: 10.3390/w11112372 Authors: Alvaro Gallo-Cordova María del Puerto Morales Eva Mazarío Solid phase extraction using magnetic nanoparticles has represented a leap forward in terms of the improvement of water quality, preventing the contamination of industrial effluents from discharge in a more efficient...
Water
Wed Nov 13, 2019 02:00
Water, Vol. 11, Pages 2373: Long-Term Hydropower Generation Scheduling of Large-Scale Cascade Reservoirs Using Chaotic Adaptive Multi-Objective Bat Algorithm
Water, Vol. 11, Pages 2373: Long-Term Hydropower Generation Scheduling of Large-Scale Cascade Reservoirs Using Chaotic Adaptive Multi-Objective Bat Algorithm Water doi: 10.3390/w11112373 Authors: Lyuwen Su Kan Yang Hu Hu Zhe Yang With growing concerns over renewable energy, the cascade hydropower reservoirs operation (CHRO), which balances the development of economic benefits and power supply security, plays an increasingly important role in hydropower systems. Due to conflicting...
Water
Wed Nov 13, 2019 02:00
Water, Vol. 11, Pages 2371: Flood Risk Mapping Worldwide: A Flexible Methodology and Toolbox
Water, Vol. 11, Pages 2371: Flood Risk Mapping Worldwide: A Flexible Methodology and Toolbox Water doi: 10.3390/w11112371 Authors: Hanne Glas Ivan Rocabado Steven Huysentruyt Edith Maroy Danitza Salazar Cortez Kobe Coorevits Philippe De Maeyer Greet Deruyter Flood risk assessments predict the potential consequences of flooding, leading to more effective risk management and strengthening resilience. However, adequate assessments rely on large quantities of high-quality...
Water
Wed Nov 13, 2019 02:00

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