Antioxidants, Vol. 8, Pages 569: Comparison of the Biological Impact of UVA and UVB upon the Skin with Functional Proteomics and Immunohistochemistry Antioxidants doi: 10.3390/antiox8120569 Authors: Wang Hung Lin Fang Yang Chen Pan The skin provides protection against external stimuli; however, solar radiation, including ultraviolet A (UVA) and ultraviolet B (UVB), can result in profound influences on skin structure and function, which eventually impairs its...
Wed Nov 20, 2019 02:00
Antioxidants, Vol. 8, Pages 571: Andrographolide, a Natural Antioxidant: An Update Antioxidants doi: 10.3390/antiox8120571 Authors: Mussard Cesaro Lespessailles Legrain Berteina-Raboin Toumi Traditionally, Andrographis paniculata has been used as an herbal remedy for lung infection treatments. Its leaves contain a diterpenoid labdane called andrographolide responsible for a wide range of biological activities such as antioxidant, anti-inflammatory, and anti-cancer...
Wed Nov 20, 2019 02:00
Antioxidants, Vol. 8, Pages 570: The Important Role of CoQ10 in Aging Antioxidants doi: 10.3390/antiox8120570 Authors: López-Lluch Coenzyme Q10 (CoQ10) is an essential lipid present in all cell membranes[...]
Wed Nov 20, 2019 02:00
Antioxidants, Vol. 8, Pages 568: Bee Collected Pollen and Bee Bread: Bioactive Constituents and Health Benefits Antioxidants doi: 10.3390/antiox8120568 Authors: Mărgăoan Stranț Varadi Topal Yücel Cornea-Cipcigan Campos Vodnar Bee products were historically used as a therapheutic approach and in food consumption, while more recent data include important details that could validate them as food supplements due to their bioproperties, which support their future...
Wed Nov 20, 2019 02:00
Arts, Vol. 8, Pages 153: Gendering the Japanese Empire: Ri Kōran as ‘Transnational’ Star? Arts doi: 10.3390/arts8040153 Authors: Kirsch This paper aims to assess how Ri Kōran came to represent the gender dichotomies of the Japanese Empire. Looking at two propaganda films, Suzhou Nights (1941) and Sayon’s Bell (1943), I will work out how the roles she played are indicative of the gender roles in the Japanese Empire, taking into account her transnational star persona.
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Atmosphere, Vol. 10, Pages 727: Projecting the Most Likely Annual Urban Heat Extremes in the Central United States Atmosphere doi: 10.3390/atmos10120727 Authors: Jahn Gallus Nguyen Pan Cetin Byon Manuel Zhou Jahani Climate studies based on global climate models (GCMs) project a steady increase in annual average temperature and severe heat extremes in central North America during the mid-century and beyond. However, the agreement of observed trends with...
Wed Nov 20, 2019 02:00
Behavioral Sciences, Vol. 9, Pages 118: Social and Psychological Predictors of Youths’ Attitudes to Cryptocurrency Behavioral Sciences doi: 10.3390/bs9120118 Authors: Gagarina Nestik Drobysheva The objectives of the study were to verify the “Attitudes Toward Cryptocurrencies Questionnaire” and to identify predictors of attitudes toward Bitcoin. Sample: 262 participants aged 17 to 30, of which 45% were male. Methods: Associations, “Value Scale”,...
Wed Nov 20, 2019 02:00
Behavioral Sciences, Vol. 9, Pages 117: A Theory of Guilt Appeals: A Review Showing the Importance of Investigating Cognitive Processes as Mediators between Emotion and Behavior Behavioral Sciences doi: 10.3390/bs9120117 Authors: Graton Aurélien Mailliez Melody Guilt appeals in the field of persuasion are quite common. However, the effectiveness of these messages is sometimes ambivalent. It is widely acknowledged that guilt leads people to engage into prosocial behaviors, but the...
Wed Nov 20, 2019 02:00
Bioengineering, Vol. 6, Pages 107: Structures and Applications of Thermoresponsive Hydrogels and Nanocomposite-Hydrogels Based on Copolymers with Poly (Ethylene Glycol) and Poly (Lactide-Co-Glycolide) Blocks Bioengineering doi: 10.3390/bioengineering6040107 Authors: Maeda Thermoresponsive hydrogels showing biocompatibility and degradability have been under intense investigation for biomedical applications, especially hydrogels composed of hydrophilic poly(ethylene glycol) (PEG) and...
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Bioengineering, Vol. 6, Pages 106: Functional Characterization and Genomic Analysis of the Chlorantraniliprole-Degrading Strain Pseudomonas Sp. GW13 Bioengineering doi: 10.3390/bioengineering6040106 Authors: Gao Li You Chlorantraniliprole (CAP) is a widely used insecticide in many areas due to its excellent insecticidal ability and mammalian safety, however, the removal of CAP has not been extensively studied. In this study, a bacterial strain GW13, which is capable of co-metabolizing...
Wed Nov 20, 2019 02:00
Biomimetics, Vol. 4, Pages 74: A Case Study of Adding Proactivity in Indoor Social Robots Using Belief–Desire–Intention (BDI) Model Biomimetics doi: 10.3390/biomimetics4040074 Authors: Ujjwal K. C. Jacques Chodorowski The rise of robots and robotics has proved to be a benefaction to humankind in different aspects. Robotics evolved from a simple button, has seen massive development over the years. Consequently, it has become an integral part of human life as robots are used for a wide...
Wed Nov 20, 2019 02:00
Biomolecules, Vol. 9, Pages 755: Lobatamunsolides A–C, Norlignans from the Roots of Pueraria lobata and their Nitric Oxide Inhibitory Activities in Macrophages Biomolecules doi: 10.3390/biom9120755 Authors: Jo Yu Lee Lee Cho Park Kim Phytochemical investigation of the methanol (MeOH) extract of Pueraria lobata roots, known as “kudzu”, combined with liquid chromatography/mass spectrometry (LC/MS)-based analysis, resulted in the identification...
Wed Nov 20, 2019 02:00
Biomolecules, Vol. 9, Pages 754: Poly-(γ-glutamic acid) Production and Optimization from Agro-Industrial Bioresources as Renewable Substrates by Bacillus sp. FBL-2 through Response Surface Methodology Biomolecules doi: 10.3390/biom9120754 Authors: Song Reddy Charalampopoulos Wee We optimized culture conditions using Bacillus sp. FBL-2 as a poly-(γ-glutamic acid) (PGA) producing strain isolated from cheonggukjang. All experiments were performed under aerobic conditions...
Wed Nov 20, 2019 02:00
Biomolecules, Vol. 9, Pages 753: Genomic, Transcriptomic and Enzymatic Insight into Lignocellulolytic System of a Plant Pathogen Dickeya sp. WS52 to Digest Sweet Pepper and Tomato Stalk Biomolecules doi: 10.3390/biom9120753 Authors: Yang Lin Singh Xu Chen Yuan Zou Li Zhang Abstract: Dickeya sp., a plant pathogen, causing soft rot with strong pectin degradation capacity was taken for the comprehensive analysis of its corresponding biomass degradative system,...
Wed Nov 20, 2019 02:00
Biomolecules, Vol. 9, Pages 752: Hydrogen Sulfide Effects on the Survival of Lactobacilli with Emphasis on the Development of Inflammatory Bowel Diseases Biomolecules doi: 10.3390/biom9120752 Authors: Kushkevych Kotrsová Dordević Buňková Vítězová Amedei The gut microbiota is a complex component of humans that depends on diet, host genome, and lifestyle. The background: The study purpose is to find relations between nutrition, intestinal lactic acid bacteria (LAB)...
Wed Nov 20, 2019 02:00
Biosensors, Vol. 9, Pages 138: The Influence of the Parameters of a Gold Nanoparticle Deposition Method on Titanium Dioxide Nanotubes, Their Electrochemical Response, and Protein Adsorption Biosensors doi: 10.3390/bios9040138 Authors: Paradowska Arkusz Pijanowska The goal of this research was to find the best conditions to prepare titanium dioxide nanotubes (TNTs) modified with gold nanoparticles (AuNPs). This paper, for the first time, reports on the influence of the parameters...
Wed Nov 20, 2019 02:00
Brain Sciences, Vol. 9, Pages 332: Cannabis Influences the Putative Cytokines-Related Pathway of Epilepsy among Egyptian Epileptic Patients Brain Sciences doi: 10.3390/brainsci9120332 Authors: M.Taalab Mohammed Helmy Othman Darwish Hassan Abbas The study aims to investigate: (1) the prevalence of cannabis among epileptic patients seen at Mansoura University Hospital, (2) serum levels and gene expression of cytokines in epilepsy patients and the controls. and...
Wed Nov 20, 2019 02:00
Brain Sciences, Vol. 9, Pages 331: Behavioral Indices of Neuropsychological Processing Implicated in Moral Domain Reasoning amongst Children and Adolescents Brain Sciences doi: 10.3390/brainsci9120331 Authors: Caravita Astrologo Biancardi Antonietti Moral domain theory posits that moral knowledge is organized in separate domains related to moral and socio-conventional rules, with the latter being reliant on a statement made by authority. Domains may be contingent on different...
Wed Nov 20, 2019 02:00
Cancers, Vol. 11, Pages 1830: Does an Alternative Sunitinib Dosing Schedule Really Improve Survival Outcomes over a Conventional Dosing Schedule in Patients with Metastatic Renal Cell Carcinoma? An Updated Systematic Review and Meta-Analysis Cancers doi: 10.3390/cancers11121830 Authors: Chung Kang Kim Kim Lee Hong Cho Treatment-related adverse events (AEs) can obfuscate the maintenance of a conventional schedule of sunitinib in patients with metastatic renal...
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Cancers, Vol. 11, Pages 1829: Prospective Evaluation of the Concordance of Commercial Circulating Tumor DNA Alterations with Tumor-Based Sequencing across Multiple Soft Tissue Sarcoma Subtypes Cancers doi: 10.3390/cancers11121829 Authors: Bryce Demoret Jeff Gregg David A. Liebner Gabriel Tinoco Scott Lenobel James L. Chen Soft tissue sarcomas (STS) are diverse tumors with heterogenous alterations. Platforms to detect circulating tumor DNA (ctDNA) have rapidly increased...
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Cancers, Vol. 11, Pages 1831: The Role of 18F-FDG PET/CT in Staging and Prognostication of Mantle Cell Lymphoma: An Italian Multicentric Study Cancers doi: 10.3390/cancers11121831 Authors: Domenico Albano Riccardo Laudicella Paola Ferro Michela Allocca Elisabetta Abenavoli Ambra Buschiazzo Alessia Castellino Agostino Chiaravalloti Annarosa Cuccaro Lea Cuppari Rexhep Durmo Laura Evangelista Viviana Frantellizzi Sofya Kovalchuk Flavia Linguanti Giulia...
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Cancers, Vol. 11, Pages 1828: Synergy of Ginkgetin and Resveratrol in Suppressing VEGF-Induced Angiogenesis: A Therapy in Treating Colorectal Cancer Cancers doi: 10.3390/cancers11121828 Authors: Hu Chan Duan Wang Kong Dong Tsim Ginkgetin, a biflavone from Ginkgo biloba leaf, and resveratrol, a polyphenol found in grape and wine, are two phytochemicals being identified for its binding to vascular endothelial growth factor (VEGF): the binding, therefore, resulted...
Wed Nov 20, 2019 02:00
Cancers, Vol. 11, Pages 1827: FLT3-ITD Activates RSK1 to Enhance Proliferation and Survival of AML Cells by Activating mTORC1 and eIF4B Cooperatively with PIM or PI3K and by Inhibiting Bad and BIM Cancers doi: 10.3390/cancers11121827 Authors: Watanabe Nogami Okada Akiyama Umezawa Miura FLT3-ITD is the most frequent tyrosine kinase mutation in acute myeloid leukemia (AML) associated with poor prognosis. We previously found that FLT3-ITD activates the mTORC1/S6K/4EBP1...
Wed Nov 20, 2019 02:00
Cancers, Vol. 11, Pages 1824: High Somatic Mutation and Neoantigen Burden Do Not Correlate with Decreased Progression-Free Survival in HCC Patients not Undergoing Immunotherapy Cancers doi: 10.3390/cancers11121824 Authors: Mauriello Zeuli Cavalluzzo Petrizzo Tornesello Buonaguro Ceccarelli Tagliamonte Buonaguro Cancer genome instability leads to accumulation of mutations which may result into tumor-specific mutated “neoantigens”, not...
Wed Nov 20, 2019 02:00
Cancers, Vol. 11, Pages 1822: Immunotherapy: A Challenge of Breast Cancer Treatment Cancers doi: 10.3390/cancers11121822 Authors: García-Aranda Redondo Breast cancer is the most commonly diagnosed cancer in women and is a leading cause of cancer death in women worldwide. Despite the significant benefit of the use of conventional chemotherapy and monoclonal antibodies in the prognosis of breast cancer patients and although the recent approval of the anti-PD-L1 antibody atezolizumab...
Wed Nov 20, 2019 02:00
Cancers, Vol. 11, Pages 1825: MicroRNA-Mediated Metabolic Reprograming in Renal Cancer Cancers doi: 10.3390/cancers11121825 Authors: Bogusławska Popławski Alseekh Koblowska Iwanicka-Nowicka Rybicka Kędzierska Głuchowska Hanusek Tański Fernie Piekiełko-Witkowska Metabolic reprogramming is one of the hallmarks of renal cell cancer (RCC). We hypothesized that altered metabolism of RCC cells results from dysregulation of microRNAs targeting metabolically...
Wed Nov 20, 2019 02:00
Cancers, Vol. 11, Pages 1823: The Transfer of Sphingomyelinase Contributes to Drug Resistance in Multiple Myeloma Cancers doi: 10.3390/cancers11121823 Authors: Faict Oudaert D’Auria Dehairs Maes Vlummens Veirman Bruyne Fostier Broek Schots Vanderkerken Swinnen Menu Multiple myeloma (MM) is well-known for the development of drug resistance, leading to relapse. Therefore, finding novel treatment strategies remains necessary. By performing...
Wed Nov 20, 2019 02:00
Cancers, Vol. 11, Pages 1821: LSD1/KDM1A, a Gate-Keeper of Cancer Stemness and a Promising Therapeutic Target Cancers doi: 10.3390/cancers11121821 Authors: Karakaidos Verigos Magklara A new exciting area in cancer research is the study of cancer stem cells (CSCs) and the translational implications for putative epigenetic therapies targeted against them. Accumulating evidence of the effects of epigenetic modulating agents has revealed their dramatic consequences on cellular reprogramming...
Wed Nov 20, 2019 02:00
Cancers, Vol. 11, Pages 1826: Molecular Targeting Therapy against EGFR Family in Breast Cancer: Progress and Future Potentials Cancers doi: 10.3390/cancers11121826 Authors: Maennling Tur Niebert Klockenbring Zeppernick Gattenlöhner Meinhold-Heerlein Hussain ：The epidermal growth factor receptor (EGFR) family contains four transmembrane tyrosine kinases (EGFR1/ErbB1, Her2/ErbB2, Her3/ErbB3 and Her4/ErbB4) and 13 secreted polypeptide ligands. EGFRs are overexpressed...
Wed Nov 20, 2019 02:00
Cells, Vol. 8, Pages 1475: Mitochondrial MiRNA in Cardiovascular Function and Disease Cells doi: 10.3390/cells8121475 Authors: Song Hu Zhang MicroRNAs (miRNAs) are small noncoding RNAs functioning as crucial post-transcriptional regulators of gene expression involved in cardiovascular development and health. Recently, mitochondrial miRNAs (mitomiRs) have been shown to modulate the translational activity of the mitochondrial genome and regulating mitochondrial protein expression...
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Cells, Vol. 8, Pages 1476: Upregulation of Mitochondrial Redox Sensitive Proteins in LPS-Treated Stefin B-Deficient Macrophages Cells doi: 10.3390/cells8121476 Authors: Trstenjak Prebanda Završnik Turk Kopitar Jerala Stefin B (cystatin B) is an intracellular inhibitor of cysteine cathepsins and mutations in the stefin B gene, resulting in the development of Unverricht–Lundborg disease, which is a form of myoclonic epilepsy. It was suggested that a key mechanism...
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Cells, Vol. 8, Pages 1474: CD271+ Human Mesenchymal Stem Cells Show Antiarrhythmic Effects in a Novel Murine Infarction Model Cells doi: 10.3390/cells8121474 Authors: Sadraddin Gaebel Skorska Lux Sasse Ahmad Vasudevan Steinhoff David Background: Ventricular arrhythmias (VA) are a common cause of sudden death after myocardial infarction (MI). Therefore, developing new therapeutic methods for the prevention and treatment of VA is of prime importance. Methods:...
Wed Nov 20, 2019 02:00
Cells, Vol. 8, Pages 1473: An EPAC1/PDE1C-Signaling Axis Regulates Formation of Leading-Edge Protrusion in Polarized Human Arterial Vascular Smooth Muscle Cells Cells doi: 10.3390/cells8121473 Authors: Paulina Brzezinska Donald H. Maurice Pharmacological activation of protein kinase A (PKA) reduces migration of arterial smooth muscle cells (ASMCs), including those isolated from human arteries (HASMCs). However, when individual migration-associated cellular events, including the polarization...
Wed Nov 20, 2019 02:00
Cells, Vol. 8, Pages 1472: Enhanced Host Neovascularization of Prevascularized Engineered Muscle Following Transplantation into Immunocompetent versus Immunocompromised Mice Cells doi: 10.3390/cells8121472 Authors: Perry Merdler Elishaev Levenberg : Engineering of functional tissue, by combining either autologous or allogeneic cells with biomaterials, holds promise for the treatment of various diseases and injuries. Prevascularization of the engineered tissue was shown to...
Wed Nov 20, 2019 02:00
Cells, Vol. 8, Pages 1471: Tauroursodeoxycholate—Bile Acid with Chaperoning Activity: Molecular and Cellular Effects and Therapeutic Perspectives Cells doi: 10.3390/cells8121471 Authors: Kusaczuk Tauroursodeoxycholic acid (TUDCA) is a naturally occurring hydrophilic bile acid that has been used for centuries in Chinese medicine. Chemically, TUDCA is a taurine conjugate of ursodeoxycholic acid (UDCA), which in contemporary pharmacology is approved by Food and Drug Administration (FDA)...
Wed Nov 20, 2019 02:00
Diagnostics, Vol. 9, Pages 198: Evaluation of Hepatic Steatosis in Rodents by Time-Domain Nuclear Magnetic Resonance Diagnostics doi: 10.3390/diagnostics9040198 Authors: João A.B. Pedroso João Paulo Camporez Luciana T. Belpiede Rafaela S. Pinto José Cipolla-Neto Donato Jose Devices that analyze body composition of rodents by time-domain nuclear magnetic resonance (TD-NMR) are becoming popular in research centers that study metabolism. Theoretically, TD-NMR devices can...
Wed Nov 20, 2019 02:00
Diversity, Vol. 11, Pages 220: Chloroplast Genome-Based Hypervariable Markers for Rapid Authentication of Six KoreanPyropia Species Diversity doi: 10.3390/d11120220 Authors: Choi Kim Choi We previously established that polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) analysis using partial plastid rbcL and mitochondrial trnC–trnP gene sequences can be used to distinguish the six representative Pyropia species produced via mariculture in...
Wed Nov 20, 2019 02:00
Diversity, Vol. 11, Pages 221: Morphometric Evaluation of Phenotypic Groups of Creole Cattle of Southern Ecuador Diversity doi: 10.3390/d11120221 Authors: Edgar Lenin Aguirre-Riofrio Rodrigo Medardo Abad-Guamán Melania de Lourdes Uchuari-Pauta The breeding of creole cattle from the southern region of Ecuador, also known as Criollo Lojano, is a source of economic support and work for the communities located in the remote areas of the Andes mountains in this region. These cattle...
Wed Nov 20, 2019 02:00
Environments, Vol. 6, Pages 121: Seasonal Emergence and Historical Contaminant Exposure of Cave Myotis (Myotis velifer) in Central Texas and Current Status of the Population Environments doi: 10.3390/environments6120121 Authors: Land Clark Pekins Lacher We examined the emergence patterns of Myotis velifer in central Texas in 2000 and assessed exposure to pesticide residues. We collected and analyzed guano from three caves for pesticide residues. In addition, bat carcasses...
Wed Nov 20, 2019 02:00
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