Background: Although mechanical thrombectomy has become the standard of care for large-vessel occlusion, the role of conscious sedation versus general anesthesia (GA) with intubation during thrombectomy remains controversial. Aphasia may increase patient agitation or apparent uncooperativeness/confusion and thereby lead to higher use of GA. The purpose of this study was to identify risk factors for GA and determine if the side of vessel occlusion potentially impacts GA rates. Materials and Methods:...
Tue Sep 17, 2019 03:00
No abstract available
Tue Sep 17, 2019 03:00
Abstract Background This study evaluates the efficacy of osimertinib for the treatment of previously epidermal growth factor receptor tyrosine kinase inhibitors (EFGR-TKI) treated non-small cell lung cancer (NSCLC) patients. Method Research articles reporting the efficacy of osimertinib for NSCLC patients were identified from literature databases (Embase,...
Thu Sep 19, 2019 03:00
A novel application of the liquid chromatography method combined with the triple quadrupole tandem mass spectrometry method was developed for the quantification of vitamin K1 and two forms of vitamin K2 (menaquinone-4, menaquinone-7) in human serum. Total chromatography time for each run was 9 min. Time required for the sample pretreatment procedures was approximately 4 h. The coefficients of variation (CVs) of intra-assay were 10.4%, 3.2 % and 2.3% for vitamin K1 in three levels of quality control...
Thu Sep 19, 2019 03:00
Background Recent studies showed that circRNAs are involved in the biological process of some human cancers. However, little is known about their functions in colorectal cancer (CRC). Methods Here we first revealed the expression profiles of circRNAs in the CRC tissues and the adjacent non-tumorous tissues using high-throughput sequencing. The sequence feature, chromosome location, alternative splicing and other characteristics...
Thu Sep 19, 2019 03:00
The rumen microbiota of ruminants plays a vital role in fiber digestion, and environmental factors affect its community structure. The yak (Bos grunniens) is the main livestock species that inhabits the Qinghai-Tibet Plateau (QTP) at regions located at high-altitude of 3,000–5,000 m. This work investigated the rumen bacterial community of yak that grazed on the QTP during the whole year to evaluate the relationship between the rumen bacterial community and the nutrient composition of forage plant...
Thu Sep 19, 2019 03:00
Microphthalminae Hartmann-Schröder, 1971 was proposed in Hesionidae to include Microphthalmus and Hesionides; however, the affinities of these genera to other members of Hesionidae have been debated, and some authors have concluded they do not belong in Hesionidae. Herein, based on morphological characters, a phylogenetic analysis of the subfamily and some other similar poorly-known genera, with an uncertain position in Hesionidae was performed to clarify their affinities. Our results indicate that...
Thu Sep 19, 2019 03:00
The Katalalixar National Reserve (KNR) lies in an isolated marine protected area of Magellan Sub-Antarctic channels, which represent an important area for marine biodiversity and macroalgal conservation. The present study is the first report of the species Lessonia spicata, “huiro negro”, in the Magellan Sub-Antarctic channels. This finding has implications for macroalgal biogeography and conservation concerns in the Chilean coast. In the ecological assessments of the KNR in 2018 we found populations...
Thu Sep 19, 2019 03:00
A new istiodactylid pterosaur, Nurhachius luei sp. nov., is here reported based on a complete skull with mandible and some cervical vertebrae from the lower part of the Jiufotang Formation of western Liaoning (China). This is the second species of Nurhachius, the type-species being N. ignaciobritoi from the upper part of the Jiufotang Formation. A revised diagnosis of the genus Nurhachius is provided, being this taxon characterized by the presence of a slight dorsal deflection of the palatal anterior...
Thu Sep 19, 2019 03:00
Background Athletic performance is affected by emotional state. Athletes may underperform in competition due to poor emotion regulation. Movement speed plays an important role in many competition events. Flexible control of movement speed is critical for effective athletic performance. Although behavioral evidence showed that negative emotion can influence movement speed, the nature of the relationship remains controversial. Thus, the present study investigated how negative emotion...
Thu Sep 19, 2019 03:00
Examination of how the ankle and midtarsal joints modulate stiffness in response to increased force demand will aid understanding of overall limb function and inform the development of bio-inspired assistive and robotic devices. The purpose of this study is to identify how ankle and midtarsal joint quasi-stiffness are affected by added body mass during over-ground walking. Healthy participants walked barefoot over-ground at 1.25 m/s wearing a weighted vest with 0%, 15% and 30% additional body mass....
Thu Sep 19, 2019 03:00
Background To identify pivotal lncRNAs in papillary thyroid cancer (PTC) using lncRNA–mRNA–miRNA ceRNA network analysis. Methods We obtained gene expression profiles from the gene expression omnibus database. Cancer specific lncRNA, cancer specific miRNA and cancer specific mRNA were identified. An integrated analysis was conducted to detect potential lncRNA–miRNA–mRNA ceRNA in regulating disease transformation. The lncRNA regulated gene ontology (GO) terms and regulated pathways were...
Thu Sep 19, 2019 03:00
Langerhans cell histiocytosis (LCH) is characterised by tissue destruction caused by the abnormal proliferation of pathogenic dendritic cells. We report a rare case of multi-system LCH with local invasion of the orbital apex.A 56-year-old woman suffered from a decrease of visual acuity in the left eye caused by central scotoma and the limitation of eye movement in all directions. Magnetic resonance imaging revealed an enhanced lesion in the left orbital apex, suggesting optic nerve compression. She...
Thu Sep 19, 2019 11:17
We present a rare case of prostatic endobronchial metastases that was successfully treated with total androgen blockade (TAB). This case demonstrates prolonged remission on continuous TAB and continued remission employing intermittent therapy.Case Rep Oncol 2019;12:715–720
Thu Sep 19, 2019 11:18
Cutaneous metastasis from anal cancer is rare at the initial diagnosis. There is a dearth of information on definitive treatment for anal cancer with cutaneous metastasis. We report the case of a 63-year-old female with locally advanced anal cancer and solitary cutaneous nodular metastasis in the right labia majora identified at the initial diagnosis that was successfully treated with definitive chemoradiotherapy. She arrived at our hospital with complaints of an enlarging perineal itching nodule....
Thu Sep 19, 2019 11:18
Publication date: 15 January 2020Source: Talanta, Volume 207Author(s): Flavio Della Pelle, Lucas Blandón-Naranjo, Manuela Alzate, Michele Del Carlo, Dario CompagnoneAbstractIn this work, for the first time, the direct usability of natural products, catechins (CT) and cocoa powder (CO), as electrochemical mediators able to modify a carbon black modified screen-printed electrode (SPE-CB) is proved, and, as proof of applicability, free (GSH) and total glutathione (GSH + GSSG) in blood samples is successfully...
Thu Sep 19, 2019 12:23
Publication date: 15 January 2020Source: Talanta, Volume 207Author(s): Arzu Yay, Mustafa Serdar Onses, Ertugrul Sahmetlioglu, Ayse Ceyhan, Sami Pekdemir, Gozde Ozge Onder, Gulay Sezer, Zeynep Soyer Sarica, Funda AydinAbstractThe aim of this work is to clarify the effect of curcumin and beta-carotene on cisplatin-induced tissue damage and to demonstrate the potential of Raman spectroscopy to detect tissue changes consistent with liver and kidney histopathology as a potential diagnostic adjunct. İn...
Thu Sep 19, 2019 12:23
Publication date: 15 January 2020Source: Talanta, Volume 207Author(s): Olga Domínguez-Renedo, A. Marta Navarro-Cuñado, Victor Arnáiz-Lozano, M. Asunción Alonso-LomilloAbstractThis work describes the development of an electrochemical sensor based on a molecularly imprinted polymer (MIP) for sensitive and selective determination of 4-ethylphenol in wine. The sensor has been built by means of the electrosynthesis of the MIP on a glassy carbon electrode surface using cyclic voltammetry. The electropolymerization...
Thu Sep 19, 2019 12:23
New England Journal of Medicine, Volume 381, Issue 12, Page 1185-1185, September 2019.
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Publication date: Available online 18 September 2019Source: BrachytherapyAuthor(s): Mahdieh Afkhami Ardekani, Hamed GhaffariAbstractPurposeThe objective of this overview was to critically evaluate the effect of polyethylene glycol (PEG)-based hydrogel spacers during prostate brachytherapy with regard to dosimetric and clinical benefits, as well as procedure-related toxicity.Methods and MaterialsA systematic search in the PubMed database was performed.ResultsA total of 12 studies, involving 615 patients...
Thu Sep 19, 2019 13:01
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