IJNS, Vol. 5, Pages 36: Editorial for Special Issue “Newborn Screening for Sickle Cell Disease and other Haemoglobinopathies” International Journal of Neonatal Screening doi: 10.3390/ijns5040036 Authors: Colombatti Cela Elion Lobitz Sickle cell disease (SCD) is among the most common genetic disorders in the world, affectingover 300,000 newborns annually, with estimates for further increases to over 400,000 annual birthswithin the next generation and with a wider geographical...
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JCM, Vol. 8, Pages 1502: Trajectories of Biological Values and Vital Parameters: An Observational Cohort Study of Adult Patients with Sickle Cell Disease Hospitalized for a Non-Complicated Vaso-Occlusive Crisis Journal of Clinical Medicine doi: 10.3390/jcm8091502 Authors: Veil Bussy Looten Arlet Pouchot Jannot Ranque Hospital admission of patients with sickle-cell disease (SCD) presenting with a vaso-occlusive crisis (VOC) can be justified by pain refractory...
Thu Sep 19, 2019 03:00
JCM, Vol. 8, Pages 1500: Subtyping Lung Cancer Using DNA Methylation in Liquid Biopsies Journal of Clinical Medicine doi: 10.3390/jcm8091500 Authors: Nunes Diniz Moreira-Barbosa Constâncio Silva Oliveira Soares Paulino Cunha Rodrigues Antunes Henrique Jerónimo Background: Lung cancer (LCa) is the most frequently diagnosed and lethal cancer worldwide. Histopathological subtyping, which has important therapeutic and prognostic implications,...
Thu Sep 19, 2019 03:00
JCM, Vol. 8, Pages 1501: Are Oral Implants the Same As Teeth? Journal of Clinical Medicine doi: 10.3390/jcm8091501 Authors: Albrektsson Osseointegration of oral implants was initially discovered by Brånemark [...]
Thu Sep 19, 2019 03:00
JCM, Vol. 8, Pages 1497: Efficacy of Different Energy Levels Used in Focused and Radial Extracorporeal Shockwave Therapy in the Treatment of Plantar Fasciitis: A Meta-Analysis of Randomized Placebo-Controlled Trials Journal of Clinical Medicine doi: 10.3390/jcm8091497 Authors: Wang Chen Huang Huang Cheng Shih The objective of this study was to assess the efficacy of different energy levels used in extracorporeal shockwave therapy (ESWT) in the treatment of plantar...
Thu Sep 19, 2019 03:00
JCM, Vol. 8, Pages 1498: Efficiency of the Inclusion of Rebamipide in the Eradication Therapy for Helicobacter pylori Infection: Meta-Analysis of Randomized Controlled Studies Journal of Clinical Medicine doi: 10.3390/jcm8091498 Authors: Dmitrii N. Andreev Igor V. Maev Diana T. Dicheva Background: There has been a negative trend in the effectiveness of classic eradication therapy regimens for Helicobacter pylori (H. pylori), which has largely been determined from the emergence...
Thu Sep 19, 2019 03:00
JCM, Vol. 8, Pages 1496: Metoclopramide and Levosulpiride Use and Subsequent Levodopa Prescription in the Korean Elderly: The Prescribing Cascade Journal of Clinical Medicine doi: 10.3390/jcm8091496 Authors: Youn Huh Do-Hoon Kim Moonyoung Choi Joo-Hyun Park Do-Young Kwon Jin-Hyung Jung Kyungdo Han Yong-Gyu Park The aim of this study was to investigate the prescribing cascade phenomenon of dopaminergic drugs such as levodopa in the management of gastroprokinetic drugs...
Thu Sep 19, 2019 03:00
JCM, Vol. 8, Pages 1499: An Early, Universal Mediterranean Diet-Based Intervention in Pregnancy Reduces Cardiovascular Risk Factors in the “Fourth Trimester” Journal of Clinical Medicine doi: 10.3390/jcm8091499 Authors: Carla Assaf-Balut Nuria Garcia de la Torre Alejandra Durán Elena Bordiu Laura del Valle Cristina Familiar Johanna Valerio Inés Jimenez Miguel Angel Herraiz Nuria Izquierdo Isabelle Runkle María Paz de Miguel Carmen Montañez Ana Barabash...
Thu Sep 19, 2019 03:00
JCM, Vol. 8, Pages 1493: A New Management Technique for Symptomatic Haematomas Following Therapeutic Vacuum-Assisted Biopsy Journal of Clinical Medicine doi: 10.3390/jcm8091493 Authors: Florentina Guzmán-Aroca Juan de Dios Berná-Serna Ana Azahara García-Ortega Dolores Hernández-Gómez Juan de Dios Berná-Mestre The aim of this study was to investigate the efficacy of the vacuum-assisted biopsy (VAB) system in evacuating symptomatic haematomas after VAB excision of benign breast...
Thu Sep 19, 2019 03:00
JCM, Vol. 8, Pages 1494: Positron Emission Tomography Can Support the Diagnosis of Dialysis-Related Amyloidosis Journal of Clinical Medicine doi: 10.3390/jcm8091494 Authors: Giulia Santagati Emanuela Cataldo Valeria Columbano Antoine Chatrenet Daniele Penna Ettore Pelosi Mammar Hachemi Lurlinys Gendrot Louise Nielsen Francesco Cinquantini Patrick Saulnier Vincenzo Arena Charles Boursot Giorgina Barbara Piccoli Background: The improvements in dialysis...
Thu Sep 19, 2019 03:00
JCM, Vol. 8, Pages 1495: Follow-Up and Management of Chronic Rhinosinusitis in Adults with Primary Ciliary Dyskinesia: Review and Experience of Our Reference Centers Journal of Clinical Medicine doi: 10.3390/jcm8091495 Authors: Emilie Bequignon Laurence Dupuy Virginie Escabasse Francoise Zerah-Lancner Laurence Bassinet Isabelle Honoré Marie Legendre Marie Devars du Mayne Bruno Crestani Estelle Escudier André Coste Jean-François Papon Bernard Maître Chronic...
Thu Sep 19, 2019 03:00
JCM, Vol. 8, Pages 1492: NK Cell Plasticity in Cancer Journal of Clinical Medicine doi: 10.3390/jcm8091492 Authors: Sizhe Liu Payal Dhar Jennifer D. Wu Natural killer (NK) cells are critical immune components in controlling tumor growth and dissemination. Given their innate capacity to eliminate tumor cells without prior sensitization, NK-based therapies for cancer are actively pursued pre-clinically and clinically. However, recent data suggest that tumors could induce functional...
Thu Sep 19, 2019 03:00
Medicina, Vol. 55, Pages 608: Surgical Treatment of Infective Endocarditis in Pulmonary Position—15 Years Single Centre Experience Medicina doi: 10.3390/medicina55090608 Authors: Liekiene Bezuska Semeniene Cypiene Lebetkevicius Tarutis Barysiene Rucinskas Sirvydis Background and Objectives: Infective endocarditis in the pulmonary position is a rare disease. Isolated pulmonary valve endocarditis is extremely rare. The aim of our study was to assess patients...
Thu Sep 19, 2019 03:00
Medicina, Vol. 55, Pages 607: DNA Methylation and Micro-RNAs: The Most Recent and Relevant Biomarkers in the Early Diagnosis of Hepatocellular Carcinoma Medicina doi: 10.3390/medicina55090607 Authors: Angela Cozma Adriana Fodor Romana Vulturar Adela-Viviana Sitar-Tăut Olga Hilda Orăşan Flaviu Mureşan Cezar Login Ramona Suharoschi Hepatocellular carcinoma (HCC) is a frequently encountered cancer type, and its alarming incidence is explained by genetic and epigenetic...
Thu Sep 19, 2019 03:00
Medicina, Vol. 55, Pages 606: Lung Cryobiopsy for the Diagnosis of Interstitial Lung Diseases: A Series Contribution to a Debated Procedure Medicina doi: 10.3390/medicina55090606 Authors: Sergio Harari Francesca Cereda Federico Pane Alberto Cavazza Nikolaos Papanikolaou Giuseppe Pelosi Monica Scarioni Elisabetta Uslenghi Maurizio Zompatori Antonella Caminati Introduction: Transbronchial cryobiopsy is an alternative to surgical biopsy for the diagnosis of fibrosing...
Thu Sep 19, 2019 03:00
Membranes, Vol. 9, Pages 122: Fabrication and Characterization of Modified Graphene Oxide/PAN Hybrid Nanofiber Membrane Membranes doi: 10.3390/membranes9090122 Authors: Jian Hou Jaehan Yun Hongsik Byun In this study, a series of novel modified graphene oxide (MGO)/polyacrylonitrile (PAN) hybrid nanofiber membranes were fabricated by electrospinning a PAN solution containing up to 1.0 wt.% MGO. The GO was initially prepared by a time-saving improved Hummer’s method. Subsequently,...
Thu Sep 19, 2019 03:00
Metabolites, Vol. 9, Pages 192: Involvement of Spermidine in the Reduced Lifespan of Caenorhabditis elegans During Vitamin B12 Deficiency Metabolites doi: 10.3390/metabo9090192 Authors: Bito Okamoto Otsuka Yabuta Arima Kawano Watanabe Vitamin B12 deficiency leads to various symptoms such as neuropathy, growth retardation, and infertility. Vitamin B12 functions as a coenzyme for two enzymes involved in amino acid metabolisms. However, there is limited information...
Thu Sep 19, 2019 03:00
Metabolites, Vol. 9, Pages 191: Associations between Blood Metabolic Profile at 7 Years Old and Eating Disorders in Adolescence: Findings from Avon Longitudinal Study of Parents and Children Metabolites doi: 10.3390/metabo9090191 Authors: Santos Ferreira Hübel Herle Abdulkadir Loos Bryant-Waugh Bulik De Stavola Lawlor Micali Eating disorders are severe illnesses characterized by both psychiatric and metabolic factors. We explored the prospective...
Thu Sep 19, 2019 03:00
Microorganisms, Vol. 7, Pages 370: Bioactive Compounds of Nigella sativa Essential Oil as Antibacterial Agents against Chlamydia trachomatis D Microorganisms doi: 10.3390/microorganisms7090370 Authors: Mosolygó Mouwakeh Hussein Ali Kincses Mohácsi-Farkas Kiskó Spengler Urogenital tract infection caused by obligate intracellular bacterium Chlamydia trachomatis D (CtrD) is a leading cause of sexually transmitted diseases. Essential oil (EO) of Nigella sativa has...
Thu Sep 19, 2019 03:00
Microorganisms, Vol. 7, Pages 369: Emergence of a Novel Ehrlichia minasensis Strain, Harboring the Major Immunogenic Glycoprotein trp36 with Unique Tandem Repeat and C-Terminal Region Sequences, in Haemaphysalis hystricis Ticks Removed from Free-Ranging Sheep in Hainan Province, China Microorganisms doi: 10.3390/microorganisms7090369 Authors: Li Liu Mu Yu Fei Chang Bi Zhou Ding Yin Ehrlichia minasensis, a recently described Ehrlichia species that...
Thu Sep 19, 2019 03:00
Microorganisms, Vol. 7, Pages 371: Dynamic Changes in the Bacterial Community During the Fermentation of Traditional Chinese Fish Sauce (TCFS) and their Correlation with TCFS Quality Microorganisms doi: 10.3390/microorganisms7090371 Authors: Du Zhang Gu Song This study revealed for the first time the dynamic changes of the bacterial community during the fermentation of traditional Chinese fish sauce (TCFS) using high-throughput sequencing. In the early phase of TCFS fermentation,...
Thu Sep 19, 2019 03:00
Microorganisms, Vol. 7, Pages 368: Characterization of CRISPR-Cas Systems in Serratia marcescens Isolated from Rhynchophorus ferrugineus (Olivier, 1790) (Coleoptera: Curculionidae) Microorganisms doi: 10.3390/microorganisms7090368 Authors: Maria Scrascia Pietro D’Addabbo Roberta Roberto Francesco Porcelli Marta Oliva Carla Calia Anna Maria Dionisi Carlo Pazzani The CRISPR-Cas adaptive immune system has been attracting increasing scientific interest for biological...
Thu Sep 19, 2019 03:00
Microorganisms, Vol. 7, Pages 367: Sample Preservation and Storage Significantly Impact Taxonomic and Functional Profiles in Metaproteomics Studies of the Human Gut Microbiome Microorganisms doi: 10.3390/microorganisms7090367 Authors: Oskar Hickl Anna Heintz-Buschart Anke Trautwein-Schult Rajna Hercog Peer Bork Paul Wilmes Dörte Becher With the technological advances of the last decade, it is now feasible to analyze microbiome samples, such as human stool specimens,...
Thu Sep 19, 2019 03:00
Molecules, Vol. 24, Pages 3416: Exploring the Synergy Between HPTLC and HPLC-DAD for the Investigation of Wine-Making By-Products Molecules doi: 10.3390/molecules24193416 Authors: Tatiana Bernardi Olga Bortolini Alessandro Massi Gianni Sacchetti Massimo Tacchini Carmela De Risi Both environmental and economic issues are increasingly pushing for the revalorization of agri-food by-products, including those arising from wine industry. Wastes produced from wine-making processes...
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Molecules, Vol. 24, Pages 3415: Preparation and Application of Bioshell Calcium Oxide (BiSCaO) Nanoparticle-Dispersions with Bactericidal Activity Molecules doi: 10.3390/molecules24183415 Authors: Sato Ishihara Nakamura Fukuda Takayama Hiruma Murakami Fujita Yokoe Scallop-shell powder (SSP) heated at high temperature exhibits high pH and broad antimicrobial activity. Bioshell calcium oxide (BiSCaO) is an SSP composed mainly of calcium oxide. It is poorly...
Thu Sep 19, 2019 03:00
Molecules, Vol. 24, Pages 3413: Design of Peptidomimetic Functionalized Cholesterol Based Lipid Nanoparticles for Efficient Delivery of Therapeutic Nucleic Acids Molecules doi: 10.3390/molecules24183413 Authors: Ehexige Ehexige Tsogzolmaa Ganbold Xiang Yu Shuqin Han Huricha Baigude Lipid nanoparticles (LNP) are the most potent carriers for the delivery of nucleic acid-based therapeutics. The first FDA approved a short interfering RNA (siRNA) drug that uses a cationic LNP...
Thu Sep 19, 2019 03:00
Molecules, Vol. 24, Pages 3414: Selectively Charged and Zwitterionic Analogues of the Smallest Immunogenic Structure of Streptococcus Pneumoniae Type 14 Molecules doi: 10.3390/molecules24183414 Authors: Tiziana Gragnani Doretta Cuffaro Silvia Fallarini Grazia Lombardi Felicia D’Andrea Lorenzo Guazzelli Zwitterionic polysaccharides (ZPs) have been shown in recent years to display peculiar immunological properties, thus attracting the interest of the carbohydrate research...
Thu Sep 19, 2019 03:00
Molecules, Vol. 24, Pages 3411: Non-Enzymatic Electrochemical Sensor Based on Sliver Nanoparticle-Decorated Carbon Nanotubes Molecules doi: 10.3390/molecules24183411 Authors: Dongqing Xu Bingbing Hou Lisheng Qian Xueji Zhang Guodong Liu The authors report a non-enzymatic electrochemical sensor based on a sliver nanoparticle-decorated carbon nanotube (AgNPs-MWCNT). Highly-dispersed AgNPs were loaded on the MWCNT surface though a simple and facile two-step method. The morphology,...
Thu Sep 19, 2019 03:00
Molecules, Vol. 24, Pages 3401: Castanea sativa Mill. Shells Aqueous Extract Exhibits Anticancer Properties Inducing Cytotoxic and Pro-Apoptotic Effects Molecules doi: 10.3390/molecules24183401 Authors: Nunzio Antonio Cacciola Giuseppe Squillaci Mariella D’Apolito Orsolina Petillo Francesco Veraldi Francesco La Cara Gianfranco Peluso Sabrina Margarucci Alessandra Morana In this study, chestnut shells (CS) were used in order to obtain bioactive compounds through...
Thu Sep 19, 2019 03:00
Molecules, Vol. 24, Pages 3404: Synthesis, Characterization and Solubility Determination of 6-Phenyl-pyridazin-3(2H)-one in Different Pharmaceutical Solvents Molecules doi: 10.3390/molecules24183404 Authors: Faiyaz Shakeel Mohd Imran Nazrul Haq Sultan Alshehri Md. Khalid Anwer The current research work proposed the solubility data and solution thermodynamic properties of the cardiovascular agent 6-phenylpyridazin-3(2H)-one [PPD] in twelve pharmaceutical solvents at “T...
Thu Sep 19, 2019 03:00
Molecules, Vol. 24, Pages 3412: Advances in the Asymmetric Total Synthesis of Natural Products Using Chiral Secondary Amine Catalyzed Reactions of α,β-Unsaturated Aldehydes Molecules doi: 10.3390/molecules24183412 Authors: Zhonglei Wang Chirality is one of the most important attributes for its presence in a vast majority of bioactive natural products and pharmaceuticals. Asymmetric organocatalysis methods have emerged as a powerful methodology for the construction of highly enantioenriched...
Thu Sep 19, 2019 03:00
Molecules, Vol. 24, Pages 3407: Targeted Delivery of Plasminogen Activators for Thrombolytic Therapy: An Integrative Evaluation Molecules doi: 10.3390/molecules24183407 Authors: Yunn-Hwa Ma Chih-Hsin Liu Yueh Liang Jyh-Ping Chen Tony Wu In thrombolytic therapy, plasminogen activators (PAs) are still the only group of drug approved to induce thrombolysis, and therefore, critical for treatment of arterial thromboembolism, such as stroke, in the acute phase. Functionalized nanocomposites...
Thu Sep 19, 2019 03:00
Molecules, Vol. 24, Pages 3409: Drug Repurposing as an Antitumor Agent: Disulfiram-Mediated Carbonic Anhydrase 12 and Anion Exchanger 2 Modulation to Inhibit Cancer Cell Migration Molecules doi: 10.3390/molecules24183409 Authors: Soyoung Hwang Dong Min Shin Jeong Hee Hong Disulfiram has been used in the treatment of alcoholism and exhibits an anti-tumor effect. However, the intracellular mechanism of anti-tumor activity of Disulfiram remains unclear. In this study, we focused on...
Thu Sep 19, 2019 03:00
Molecules, Vol. 24, Pages 3408: Water Extraction Kinetics of Bioactive Compounds of Fucus vesiculosus Molecules doi: 10.3390/molecules24183408 Authors: Ricardo M. Ferreira Ana Ramalho Ribeiro Carla Patinha Artur M. S. Silva Susana M. Cardoso Rui Costa Brown macroalgae, particularly those from Fucus genus, are a rich and balanced source of bioactive nutrients and phytochemicals, such as dietary fibres (fucoidans, laminarins, and/or alginates), phlorotannins, and fucoxanthin,...
Thu Sep 19, 2019 03:00
Molecules, Vol. 24, Pages 3410: Nano-and Micromotors Designed for Cancer Therapy Molecules doi: 10.3390/molecules24183410 Authors: Luisa Sonntag Juliane Simmchen Veronika Magdanz Research on nano- and micromotors has evolved into a frequently cited research area with innovative technology envisioned for one of current humanities’ most deadly problems: cancer. The development of cancer targeting drug delivery strategies involving nano-and micromotors has been a vibrant...
Thu Sep 19, 2019 03:00
Molecules, Vol. 24, Pages 3405: Michaelis-Arbuzov-Type Reaction of 1-Imidoalkyltriarylphosphonium Salts with Selected Phosphorus Nucleophiles Molecules doi: 10.3390/molecules24183405 Authors: Jakub Adamek Anna Węgrzyk-Schlieter Klaudia Steć Krzysztof Walczak Karol Erfurt In this study, Michaelis-Arbuzov-type reaction of 1-imidoalkyltriarylphosphonium salts with phosphites, phosphonites, and phosphinites was used in the synthesis of a wide range of phosphorus analogs of α-amino...
Thu Sep 19, 2019 03:00
Molecules, Vol. 24, Pages 3403: Deepening Inside the Pictorial Layers of Etruscan Sarcophagus of Hasti Afunei: An Innovative Micro-Sampling Technique for Raman/SERS Analyses Molecules doi: 10.3390/molecules24183403 Authors: Rossella Gagliano Candela Livia Lombardi Alessandro Ciccola Ilaria Serafini Armandodoriano Bianco Paolo Postorino Lorella Pellegrino Maurizio Bruno The Hasti Afunei sarcophagus is a large Etruscan urn, made up of two chalky alabaster monoliths....
Thu Sep 19, 2019 03:00
Molecules, Vol. 24, Pages 3406: E-Beam Irradiation and Ozonation as an Alternative to the Sulphuric Method of Wine Preservation Molecules doi: 10.3390/molecules24183406 Authors: Magdalena Błaszak Agata Nowak Sabina Lachowicz Wojciech Migdał Ireneusz Ochmian Potassium metabisulphite is usually used for microbial stabilization in the process of vinification and wine preservation, but it is considered to be allergenic. The objective of the present study was to assess the efficiency...
Thu Sep 19, 2019 03:00
Molecules, Vol. 24, Pages 3402: Fractionated Antioxidant and Anti-inflammatory Kernel Oil from Torreya fargesii Molecules doi: 10.3390/molecules24183402 Authors: Xianrong Zhou Jin Shang Mingyi Qin Jianhua Wang Bo Jiang Hui Yang Yan Zhang Polymethylene-interrupted polyunsaturated fatty acids (PMI-PUFAs) are emerging functional lipids with proven antioxidant and anti-inflammatory effects. In this study, a typical PMI-PUFA, sciadonic acid (C20:3, 5c 11c 14c), was enriched...
Thu Sep 19, 2019 03:00
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